Oguchi Takeshi 小口健史

… Alternative Names

OGUCHI Takeshi 小口健史

小口健史オグチタケシ

Less

Researcher Number	60201399
Other IDs
Affiliation (Current)	2022: 山梨大学, 大学院総合研究部, 准教授
Affiliation (based on the past Project Information) *help	2017 – 2022: 山梨大学, 大学院総合研究部, 准教授 2015 – 2016: 山梨大学, 総合研究部, 准教授 2011 – 2013: 山梨大学, 医学工学総合研究部, 准教授 2010 – 2012: 山梨大学, 大学院・医学工学総合研究部, 准教授 2003 – 2004: UNIVERSITY OF YAMANASHI, HOSPITAL, ASSISTANT PROFESSOR, 医学部附属病院, 講師 … More 2002: UNIVERSITY OF YAMANASHI, FACULTY OF MEDICINE, ASSISTANT PROFESSOR, 医学部, 講師 1998 – 2001: 山梨医科大学, 医学部, 講師 1991: 山梨医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Anesthesiology / Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies / Basic Section 55050:Anesthesiology-related Except Principal Investigator Anesthesiology/Resuscitation studies / 麻酔学 / Anesthesiology/Resuscitation studies / Basic Section 55050:Anesthesiology-related / Basic Section 55030:Cardiovascular surgery-related
Keywords	Principal Investigator 心筋虚血 / 心筋保護 / 虚血再灌流障害 / 周術期管理学 / ウリナスタチン / TNF-α / 摘出心筋 / 摘出心臓 / 虚血再灌流 / 虚血再灌流不整脈 … More / インスリン / プレコンディショニング / 高血糖 / プロタミン / ヘパリン / 摘出心臓標本 / 筋小胞体機能 / 心機能 / 心筋代謝 / 蛍光色素法 / PROTAMINE / HEPARIN / ISOLATED HEART / CALCIUM / MYOCARDIAL FUNCTION / MYOCARDIAL METABOLISM / FURA-2 / アミノ酸 / 循環器・高血圧 / 薬理学 / フラボノイド / PI3K/Akt経路 … More Except Principal Investigator c-fos / 神経因性疼痛 / 麻酔薬 / 摘出心臓標本 / 筋小胞体機能 / 心機能 / 蛍光色素法 / ISOLATED HEART / CALCIUM / MYOCARDIAL FUNCTION / FURA-2 / allodynia / astrocyte / プレコンディショニング / 硬膜外大量フェンタニール麻酔 / 血中カテコラミン / 硬膜外フェンタニ-ル / 腹部手術 / インスリン / 虚血再灌流障害 / 心筋保護 / Insulin / preconditioning effect / rat heart / ischemia / 吸入麻酔薬 / 虚血-再灌流障害 / 細胞内pH / Na^+ / H^+交換系 / Na+ / H+交換系 / MYOCYTES / PH ACTIVITY / VOLATILE ANESTHETICS / REPERFUSION INJURY / 部分神経損傷モデル / CCIモデル / c-Fos / Neuropathic Pain / partial nerveinjury model / プロポフォール / 心筋代謝 / 静脈麻酔薬 / ANESTHETICCS / PROPOFOL / MYOCARDIAL METABOLISM / fractalkine / neurosphere / astroyte / 加齢 / 虚血心筋 / AGING / ISCHEMIC HEART / PRECONDITIONING / ANESTHETICS / ラクトフェリン / 心筋虚血再灌流障害 / 気絶心筋 / 人工心肺 / 経鼻インスリン / 脳内炎症 Less

Effects of intranasal insulin administration for acute cerebral inflammation induced by cardiopulmonary bypass
- Principal Investigator
  
  川上亜希子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  University of Yamanashi
Cardioprotective effect of lactoferrin via PI3K/Akt pathway against stunned myocardium
- Principal Investigator
  
  松川隆
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  University of Yamanashi
Role of PI3K / Akt pathway on cardioprotective effects of flavonoids against ischemia-reperfusion injuryPrincipal Investigator
- Principal Investigator
  
  小口健史
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  University of Yamanashi
Myocardial preconditioning effects of amino acids and PI3K/Akt signaling pathwayPrincipal Investigator
- Principal Investigator
  
  OGUCHI Takeshi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  University of Yamanashi
Myocardial preconditioning effects of high-dose insulin and PI3K/Akt signaling pathwayPrincipal Investigator
- Principal Investigator
  
  OGUCHI Takeshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  University of Yamanashi
Insulin preconditioning elevates p-Akt and cardiac contractility after reperfusion in the isolated ischemic rat heart
- Principal Investigator
  
  SATO Hiroaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Yamanashi
Cardio-protective effects of ulinastatin in isolated rat heartsPrincipal Investigator
- Principal Investigator
  
  OGUCHI Takeshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Yamanashi
ROLE OF AGING ON PRECONDITIONING AND INTRACELLULAR CA2+ DYNAMICS IN THE ISOLATED RAT HEART.
- Principal Investigator
  
  YAMAGUCHI Toshiaki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Yamanashi
  山梨医科大学
THE ROLE OF c-fos IN INDUCING NEUROPATHIC PAIN
- Principal Investigator
  
  KASHIMOTO Satoshi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Yamanashi
  山梨医科大学
EFFECTS OF VOLATILE ANESTHETICS ON PH ACTIVITY AND ISCHEMIC-REPERFUSION INJURY IN MYOCARDIAL CELLS
- Principal Investigator
  
  KUMAZAWA Teruo
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  UNIVERSITY OF YAMANASHI (FACULTY OF MEDICINE)
The Role of c-fos gene in Neuropathic Pain
- Principal Investigator
  
  KASHIMOTO Satoshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamanashi Medical University
AGE-RELATED ANESTHETICS EFFECTS ON MYOCARDIAL CONTRACTION AND INTRACELLULAR CA2+ DYNAMICS OF ISOLATED RAT HEARTS
- Principal Investigator
  
  YAMAGUCHI Toshiaki
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  YAMANASHI MEDICAL UNIVERSITY
EFFECTS OF PROTAMINE ON MYOCARDIAL FUNCTION AND INIRACELLULAR Ca2+ DYNAMICS IN THE ISOLATED RAT HEARTSPrincipal Investigator
- Principal Investigator
  
  OGUCHI Takeshi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  YAMANASHI MEDICAL UNIVERSITY
硬膜外へのフェンタニールを始めとするオピオイド投与による新しい麻酔法の検討
- Principal Investigator
  
  KUMAZAWA Teruo
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  麻酔学
- Research Institution
  山梨医科大学

All 2019 2013 2011 2010 2004 2003

All Journal Article Presentation

[Journal Article] Age-related changes in the cardioprotective effect of ischemic preconditioning in the isolated rat hearts : Role of intracellular calcium dynamics and oxygen free radical production2004
- Author(s)
  Takeshi Oguchi
- Journal Title
  
  American Society of Anesthesiologists Annual Meeting
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571425
[Journal Article] Age-related changes in the cardioprotective effect of ischemic preconditioning in the isolated rat hearts : Role of intracellular calcium dynamics and oxygen free radical production2004
- Author(s)
  TAKESHI OGUCHI
- Journal Title
  
  ANESTHESIOLOGY A630
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571425
[Journal Article] Aging reduces the cardioprotective effect of isoflurane-Induced preconditioning in the isolated rat hearts2003
- Author(s)
  Takeshi Oguchi
- Journal Title
  
  American Society of Anesthesiologists Annual Meeting
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571425
[Journal Article] Aging reduces the cardioprotective effect of isoflurane-Induced preconditioning in the isolated rat hearts2003
- Author(s)
  TAKESHI OGUCHI
- Journal Title
  
  ANESTHESIOLOGY A688
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571425
[Presentation] Which amino acids are cardioprotective against ischemia reperfusion injury ?2019
- Author(s)
  Keisuke Omiya, Yosuke Nakadate, Toru Matsuoka, Akiko Kawakami, Hiroaki Sato, Takeshi Oguchi, Takashi Matsukawa
- Organizer
  New Zealand Anaesthesia Annual Scientific Meeting +Annual Queenstown Update in Anaesthesia 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10955
[Presentation] 心臓虚血再灌流モデルにおける高用量インスリン先行投与の心筋保護効果2013
- Author(s)
  福島久史、佐藤宏明、佐藤環、小口健史、中楯陽介、松川隆
- Organizer
  日本麻酔科学会第60回学術集会
- Place of Presentation
  ロイトン札幌（北海道札幌市）
- Data Source
  KAKENHI-PROJECT-23592280
[Presentation] Ulinastatin, a protease inhibitor, attenuates protamine- induced cardiotoxicity in rats by inhibiting tumor necrosis factor alpha.2011
- Author(s)
  Hisashi Fukushima, Takeshi Oguchi,, Hiroaki Sato, Tamaki Sato, Takashi Matsukawa.
- Organizer
  2011 Annual Meeting of American Society of Anesthesiologists
- Place of Presentation
  McCormick Place (アメリカ合衆国シカゴ)
- Year and Date
  2011-10-16
- Data Source
  KAKENHI-PROJECT-22591724
[Presentation] Ulinastatin attenuates ischemia- reperfusion injury in the isolated rat heart2010
- Author(s)
  Hisashi Fukushima, Takeshi Oguchi,, Tadahiki Ishiyama, Hiroaki Sato, Takashi Matsukawa.
- Organizer
  2011 Annual Meeting of American Society of Anesthesiologists
- Place of Presentation
  アメリカ合衆国サンディエゴ
- Year and Date
  2010-10-17
- Data Source
  KAKENHI-PROJECT-22591724

1. KUMAZAWA Teruo (10092404)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. MATSUKAWA Takashi (80209519)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
3. ISHIYAMA Tadahiko (90293448)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. KASHIMOTO Satoshi (60152633)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 中楯陽介 (50597002)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. IIJIMA Tetuya (70324209)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. YAMAGUCHI Toshiaki (80242650)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 野中明彦 (90228338)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. SATO Hiroaki (20402026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. SUGAWARA Takeshi (50303417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 久米正記 (50205176)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 田中行夫 (40155180)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 川上亜希子 (70597004)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Oguchi Takeshi 小口 健史

OGUCHI Takeshi 小口 健史

小口 健史 オグチ タケシ

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of PI3K / Akt pathway on cardioprotective effects of flavonoids against ischemia-reperfusion injuryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Myocardial preconditioning effects of amino acids and PI3K/Akt signaling pathwayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Myocardial preconditioning effects of high-dose insulin and PI3K/Akt signaling pathwayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cardio-protective effects of ulinastatin in isolated rat heartsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

EFFECTS OF PROTAMINE ON MYOCARDIAL FUNCTION AND INIRACELLULAR Ca2+ DYNAMICS IN THE ISOLATED RAT HEARTSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Oguchi Takeshi 小口健史

OGUCHI Takeshi 小口健史

小口健史オグチタケシ