TOSHIMA Kazunobu 戸嶋一敦

… Alternative Names

戸嶋一敦トシマカズノブ

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Researcher Number	60217502
Other IDs
External Links
Affiliation (Current)	2025: 慶應義塾大学, 理工学部(矢上), 教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 慶應義塾大学, 理工学部(矢上), 教授 2016 – 2017: 慶應義塾大学, 理工学部(矢上), 教授 2003 – 2016: 慶應義塾大学, 理工学部, 教授 1998 – 2001: 慶應義塾大学, 理工学部, 助教授 1996: 慶應義塾大学, 理工学部, 助教授
Review Section/Research Field	Principal Investigator Science and Engineering / Living organism molecular science / Bioorganic chemistry / Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / Biomolecular chemistry / Science and Engineering Except Principal Investigator Environmental chemistry / Chemical pharmacy
Keywords	Principal Investigator 光分解 / 糖 / DNA / 有機合成 / タンパク / 生体機能分子 / ハイブリッド / 糖鎖 / アントラキノン / 細胞 … More / がん細胞 / 光感受性分子 / 分子デザイン / ボロン酸 / 抗細胞活性 / 分子設計 / DNA切断 / アントラセン / 光制御 / タンパク質 / 天然物 / フラーレン / アルツハイマー病 / 合成 / 生物活性分子 / ハイブリッド分子 / インターカレーター / エンジイン / アクリロイル基 / L-システイン / ヒポクレリンB / 光細胞毒性 / リン酸基 / アルカリホスファターゼ / アントラノール / 刺激応答型光感受性分子 / 光線力学療法 / 生体高分子 / 生体機能 / メイラード反応 / 最終糖化生成物 / 還元糖 / ヒドラジド / 複合化 / 中分子 / セラノスティクス / 活性酸素 / レゾルフィン / ANTICANCER AGENT / ETHIDUIM BROMIDE / TELOMERASE / CARBOHYDRATE / BULGE DNA / ANTHRACENE / PHOTOCLEAVAGE / DNA融解温度 / 核酸塩基 / DNA点変異 / フェナントリジン / 誘導体 / 抗ガン剤 / 阻害剤 / G-カルテット / 抗癌剤 / 臭化エチジウム / テロメラーゼ / バルジDNA / 光切断 / Cytotoxicity / Hybrid / Carbohydrate / Intercalator / Light / DNA Cleavage / Post-Genome / ネオカルチノスタチン / ハイブリット / 光 / ポストゲノム / 細胞毒性 / 糖タンパク / レクチン / ノロウイルス / ガラクトース / キノリン / 糖転移酵素 / 抗体 / シアリルルイスA / 生体機能光制御分子 / 標的同定 / 脱炭酸酵素 / 酸化 / イリジウム / 有機金属錯体 / PQQ / セロトニン / ハルミン / シアル酸 / HIV-1プロテア / ノイラミニダーゼ / インフルエンザ / アミロイド / エイズ / ポルフィリン / ベロ毒素 / マクロファージ / LPS / KDO / 化学合成 / HIV-1プロテアーゼ / 結核菌 / 糖鎖光分解 / マンノシド / サクラシメジレクチン / タンパク光分解 / アミロイドβ / 分子標的薬 / リゾチーム / 糖加水分解酵素 / イオン液体 / デオキシ糖 / 不飽和糖 / バイオミメティック / 配糖体 / 抗生物質 / グリコシル化反応 / グリコシル化 / 遺伝子機能制御 / 2-フェニルキノリン / 超分子 / ヘテロ原子 / 人工制限酵素 … More Except Principal Investigator Biopolyester / Solid acid / Polymerizable oligomer / Lipase / Poly(lactic acid) / Cyclic oligomer / Chemical recycling / Enzyme / バイオポリエステル / 固体酸 / 重合性オリゴマー / リパーゼ / ポリ乳酸 / 環状オリゴマー / ケミカルリサイクル / 酵素 / プロセス化学 / 不斉触媒反応 / 有機酸触媒 / 有機塩基触媒 / バイオミメティック / 有機求核触媒 / 酸・塩基複合型触媒 / 有機触媒 Less

天然物を基本骨格とする刺激応答型光感受性分子の創製と次世代型光線力学療法への応用Principal Investigator
- Principal Investigator
  
  戸嶋一敦
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Keio University
機能複合化による生体機能光制御中分子の創製Principal Investigator
- Principal Investigator
  
  戸嶋一敦
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Keio University
生体機能光制御分子の創製とケミカルバイオロジーへの応用Principal Investigator
- Principal Investigator
  
  戸嶋一敦
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Keio University
Creation of agents that selectively photo-degrade certain proteins and oligosaccharides and its application to control of cell functionsPrincipal Investigator
- Principal Investigator
  
  TOSHIMA KAZUNOBU
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Keio University
生体機能光制御分子の創製とケミカルバイオロジーへの応用Principal Investigator
- Principal Investigator
  
  戸嶋一敦
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Keio University
Creation of Novel Biofunctional Molecules for Target-Selective Photodegradation of Proteins and CarbohydratesPrincipal Investigator
- Principal Investigator
  
  KAZUNOBU Toshima
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Keio University
Development of designed agents that selectively photo-degrade certain proteins and oligosaccharidesPrincipal Investigator
- Principal Investigator
  
  TOSHIMA Kazunobu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Keio University
糖を有する生体機能分子のための新合成方法論と実践的合成法の開発Principal Investigator
- Principal Investigator
  
  戸嶋一敦
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Keio University
酸・塩基複合型有機触媒の精密設計
- Principal Investigator
  
  竹本佳司
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto University
Novel Sustainable chemical recycling of green polymers using environmentally benign catalytic process
- Principal Investigator
  
  MATSUMURA Shuichi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental chemistry
- Research Institution
  KEIO UNIVERSITY
THE DEVELOPMENT OF ARTIFICIAL GENE REGULATION MOLECULES BASED ON CHEMICAL BIOLOGYPrincipal Investigator
- Principal Investigator
  
  TOSHIMA Kazunobu
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  KEIO UNIVERSITY
Molecular Design and Evaluation of Artificial Gene Function-Regulating Agents in the Post-Genome EraPrincipal Investigator
- Principal Investigator
  
  TOSHIMA Kazunobu
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Keio University
人工設計分子とDNAの超分子形成に基いた遺伝子機能制御Principal Investigator
- Principal Investigator
  
  戸嶋一敦
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Keio University
エンジイン系人工DNA制限酵素の分子設計と機能発現制御技術の開発Principal Investigator
- Principal Investigator
  
  戸嶋一敦
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Keio University

[Book] 糖鎖の新機能開発・応用ハンドブック2015
- Author(s)
  高橋大介、戸嶋一敦
- Total Pages
  3
- Publisher
  エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-26282212
[Book] 糖鎖の新機能開発・応用ハンドブック2015
- Author(s)
  高橋大介、戸嶋一敦
- Total Pages
  3
- Publisher
  エヌ・ティー・エス
- Data Source
  KAKENHI-PUBLICLY-26102738
[Book] Comprehensive Glycosdence2007
- Author(s)
  K. Toshima
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-18032068
[Book] 有機分子触媒の新展開(柴崎正勝監修)2006
- Author(s)
  戸嶋一敦
- Total Pages
  337
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-18032068
[Book] Enzymatic Synthesis and Chemical Recycling of Green Polymers, Biodegradable Polymeric Materials and their Applications (edited by S.Mallapragada and B.Narasimhan) Volume 12005
- Author(s)
  S.Matsumura, Y.Osanai, Y.Soeda, Y.Suzuki, K.Toshima
- Publisher
  American Scientific Publishers, California, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350095
[Journal Article] Boronic-Acid-Catalyzed Regioselective and 1,2-cis-Stereoselective Glycosylation of Unprotected Sugar Acceptors via SNi-Type Mechanism2018
- Author(s)
  Tanaka Masamichi、Nakagawa Akira、Nishi Nobuya、Iijima Kiyoko、Sawa Ryuichi、Takahashi Daisuke、Toshima Kazunobu
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 140 Issue: 10 Pages: 3644-3651
- DOI
  10.1021/jacs.7b12108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K05781, KAKENHI-PUBLICLY-16H01161
[Journal Article] Systematic and Stereoselective Total Synthesis of Mannosylerythritol Lipids and Evaluation of Their Antibacterial Activity2018
- Author(s)
  Nashida Junki、Nishi Nobuya、Takahashi Yoshiaki、Hayashi Chigusa、Igarashi Masayuki、Takahashi Daisuke、Toshima Kazunobu
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: - Issue: 13 Pages: 7281-7289
- DOI
  10.1021/acs.joc.8b00032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K05781, KAKENHI-PUBLICLY-16H01161
[Journal Article] Novel 1,2-cis-Stereoselective Glycosylations Utilizing Organoboron Reagents and Their Application to Natural Products and Complex Oligosaccharide Synthesis2017
- Author(s)
  Takahashi Daisuke、Tanaka Masamichi、Nishi Nobuya、Toshima Kazunobu
- Journal Title
  
  Carbohydrate Research
  
  Volume: 452 Pages: 64-77
- DOI
  10.1016/j.carres.2017.10.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K05781, KAKENHI-PUBLICLY-16H01161
[Journal Article] Regio- and Stereoselective β-Mannosylation Using a Boronic Acid Catalyst and Its Application to the Synthesis of a Tetrasaccharide Repeating Unit of Lipopolysaccharide Derived from E. Coli O752017
- Author(s)
  N. Nishi, J. Nashida, E. Kaji, D. Takahashi, K. Toshima
- Journal Title
  
  Chemical Communications
  
  Volume: 53 Issue: 21 Pages: 3018-3021
- DOI
  10.1039/c7cc00269f
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-16H01161, KAKENHI-PROJECT-16K05781
[Journal Article] Target-Selective Fluorescence Imaging and Photocytotoxicity against H2O2 High-Expressing Cancer Cells Using a Photoactivatable Theranostic Agent2017
- Author(s)
  Takagi Ryoma、Takeda Ayano、Takahashi Daisuke、Toshima Kazunobu
- Journal Title
  
  Chemistry An Asian Journal
  
  Volume: 12 Issue: 20 Pages: 2656-2659
- DOI
  10.1002/asia.201701004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K05781, KAKENHI-PUBLICLY-16H01161
[Journal Article] Electrochemical Preparation of Platinum Nanoparticles from Bis(acetylacetonato)platinum(II) in Some Aprotic Amide-type Ionic Liquids2017
- Author(s)
  Sultana Sharmin、Tachikawa Naoki、Yoshii Kazuki、Toshima Kazunobu、Magagnin Luca、Katayama Yasushi
- Journal Title
  
  Electrochimica Acta
  
  Volume: 249 Pages: 263-270
- DOI
  10.1016/j.electacta.2017.08.021
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Journal Article] Glycosyl-Acceptor-Derived Boronic Ester-Promoted Direct and β-Stereoselective Mannosylation with a 1,2-Anhydromannose Donor2016
- Author(s)
  M. Tanaka, J. Nashida, D. Takahashi, K. Toshima
- Journal Title
  
  Organic Letters
  
  Volume: 18 Issue: 9 Pages: 2288-2291
- DOI
  10.1021/acs.orglett.6b00926
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01161, KAKENHI-PROJECT-16K05781
[Journal Article] Total Synthesis of Aquayamycin2016
- Author(s)
  S. Kusumi, H. Nakayama, T. Kobayashi, H. Kuriki, Y. Matsumoto, D. Takahashi, K. Toshima
- Journal Title
  
  Chemistry - A European Journal
  
  Volume: 22 Issue: 52 Pages: 18733-18736
- DOI
  10.1002/chem.201604697
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-16H01161, KAKENHI-PROJECT-26282212
[Journal Article] Stereocontrolled Photoinduced Glycosylation Using an Aryl Thiourea as an Organo photoacid2016
- Author(s)
  T. Kimura, T. Eto, D. Takahashi, K. Toshima
- Journal Title
  
  Organic Letters
  
  Volume: 18 Issue: 13 Pages: 3190-3193
- DOI
  10.1021/acs.orglett.6b01404
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-16H01161, KAKENHI-PROJECT-16J00784
[Journal Article] Target-selective photo-degradation of AFP-L3 and selective photo-cytotoxicity against HuH-7 hepatocarcinoma cells using an anthraquinone-PhoSL hybrid2016
- Author(s)
  M. Okuyama, H. Ueno, Y. Kobayashi, H. Kawagishi, D. Takahashi, K. Toshima
- Journal Title
  
  Chemical Communications
  
  Volume: 52 Issue: 10 Pages: 2169-2172
- DOI
  10.1039/c5cc09542e
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26102738, KAKENHI-PROJECT-26282212
[Journal Article] 1,2-cis-α-Stereoselective Glycosylation Utilizing a Glycosyl-Acceptor-Derived Boronic Ester and Its Application to the Total Synthesis of Natural Glycosphingolipids2016
- Author(s)
  M. Tanaka, D. Takahashi, K. Toshima
- Journal Title
  
  Organic Letters
  
  Volume: 18 Issue: 19 Pages: 5030-5033
- DOI
  10.1021/acs.orglett.6b02488
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-16H01161, KAKENHI-PROJECT-16K05781
[Journal Article] Target-selective Photo-degradation of a Sialyl Lewis a (sLea) Conjugate and Photo-cytotoxicity Against sLea Positive Cancer Cells Using an Anthraquinone-antibody Hybrid2016
- Author(s)
  D. Takahashi, T. Nagao, S. Sotokawa, K. Toshima
- Journal Title
  
  Medicinal Chemistry Communications
  
  Volume: 7 Issue: 6 Pages: 1224-1228
- DOI
  10.1039/c6md00167j
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01161, KAKENHI-PROJECT-26282212
[Journal Article] One-pot transformation of N-succinyl chitosan to nitrogen-containing alkyl glycosides using an ionic liquid containing a protic acid2015
- Author(s)
  M. Aoyagi, T. Kimura, A. Ohba, Y. Katayama, D. Takahashi, K. Toshima
- Journal Title
  
  Chemistry Letters
  
  Volume: 44 Issue: 11 Pages: 1467-1469
- DOI
  10.1246/cl.150623
- NAID
  130005108114
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26102738, KAKENHI-PROJECT-26282212
[Journal Article] Glycosylation of glycals using N-iodosuccinimide (NIS) and phosphorus compounds for syntheses of 2-iodo- and 2-deoxyglycosides2015
- Author(s)
  T. Kimura, D. Takahashi, K. Toshima
- Journal Title
  
  Journal of Organic Chemistry
  
  Volume: 80 Issue: 19 Pages: 9552-9562
- DOI
  10.1021/acs.joc.5b01542
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26102738, KAKENHI-PROJECT-26282212
[Journal Article] Systematic synthesis of low-molecular weight fucoidan derivatives and their effect on cancer cells2015
- Author(s)
  A. Kasai, S. Arafuka, N. Koshiba, D. Takahashi, K. Toshima
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 13 Issue: 42 Pages: 10556-10568
- DOI
  10.1039/c5ob01634g
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26102738, KAKENHI-PROJECT-26282212
[Journal Article] Chemical approach for target-selective degradation of oligosaccharides using photoactivatable organic molecules2015
- Author(s)
  K. Toshima, D. Takahashi
- Journal Title
  
  Glycoconjugate Journal
  
  Volume: 34 Issue: 7 Pages: 475-482
- DOI
  10.1007/s10719-015-9591-9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26102738, KAKENHI-PROJECT-26282212
[Journal Article] Regioselective and 1,2-cis-α-stereoselective glycosylation utilizing glycosyl-acceptor-derived boronic ester catalyst2015
- Author(s)
  A. Nakagawa, M. Tanaka, S. Hanamura, D. Takahashi, K. Toshima
- Journal Title
  
  Angewandte Chemie, International Edition
  
  Volume: 54 Issue: 37 Pages: 10935-10939
- DOI
  10.1002/anie.201504182
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26102738, KAKENHI-PROJECT-26282212
[Journal Article] Hierarchical CaCO3 Chromatography: A Stationary Phase Based on Biominerals2015
- Author(s)
  Kosuke Sato, Yuya Oaki, Daisuke Takahashi, Kazunobu Toshima, Hiroaki Imai
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 21 Issue: 13 Pages: 5034-5040
- DOI
  10.1002/chem.201405724
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22107010, KAKENHI-PROJECT-26282212
[Journal Article] Photodegradation of amyloid β and reduction of its cytotoxicity to PC12 cells using porphyrin derivatives2014
- Author(s)
  A. Hirabayashi, Y. Shindo, K. Oka, D. Takahashi, K. Toshima
- Journal Title
  
  Chemical Communications
  
  Volume: 50 Issue: 67 Pages: 9543-9546
- DOI
  10.1039/c4cc03791j
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26102738, KAKENHI-PROJECT-26282212
[Journal Article] アルツハイマー病原因物質アミロイドβを光分解する生体機能光制御分子の創製と応用2014
- Author(s)
  平林歩、石田康則、高橋大介、戸嶋一敦
- Journal Title
  
  ケミカルバイオロジー
  
  Volume: 7 Pages: 2-5
- Data Source
  KAKENHI-PUBLICLY-26102738
[Journal Article] アルツハイマー病原因物質アミロイドβを光分解する生体機能光制御分子の創製と応用2014
- Author(s)
  平林歩、石田康則、高橋大介、戸嶋一敦
- Journal Title
  
  ケミカルバイオロジー
  
  Volume: 7 Pages: 2-5
- Data Source
  KAKENHI-PROJECT-26282212
[Journal Article] A Solid-phase Affinity Labeling Method for Target-selective Isolation and Modification of Proteins2014
- Author(s)
  Kuwahara, D.; Hasumi, T.; Kaneko, H.; Takahashi, D.; Toshima, K.
- Journal Title
  
  Chemical Communications
  
  Volume: 50 Issue: 98 Pages: 15601-15604
- DOI
  10.1039/c4cc06783e
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25750387, KAKENHI-PUBLICLY-26102738, KAKENHI-PROJECT-26282212
[Journal Article] Photo-induced glycosylation using reusable organophotoacids2014
- Author(s)
  R. Iwata, K. Uda, D. Takahashi, K. Toshima
- Journal Title
  
  Chemical Communications
  
  Volume: 50 Issue: 73 Pages: 10695-10698
- DOI
  10.1039/c4cc04753b
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-26102738, KAKENHI-PROJECT-26282212
[Journal Article] Chemical and biological evaluation of unusual sugars, alpha-aculosides, as novel Michael acceptor2014
- Author(s)
  H. Ikeda, E. Kaneko, S. Okuzawa, D. Takahashi, K. Toshima
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 12 Issue: 44 Pages: 8832-8835
- DOI
  10.1039/c4ob01877j
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26102738, KAKENHI-PROJECT-26282212
[Journal Article] Systematic synthesis of sulfated oligofucosides and their effect on breast cancer MCF-7 cells2014
- Author(s)
  S. Arafuka, N. Koshiba, D. Takahashi, K. Toshima
- Journal Title
  
  Chemical Communications
  
  Volume: 50 Issue: 69 Pages: 9831-9834
- DOI
  10.1039/c4cc03544e
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-26102738, KAKENHI-PROJECT-26282212
[Journal Article] Light-induced O-glycosylation of unprotected deoxythioglycosyl donors2013
- Author(s)
  M. Nakanishi, D. Takahashi, K. Toshima
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 11 Issue: 31 Pages: 5079-5082
- DOI
  10.1039/c3ob41143e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310153, KAKENHI-PUBLICLY-24102528
[Journal Article] Chiral Bronsted acid-mediated glycosylation with recognition of alcohol chirality2013
- Author(s)
  T. Kimura, M. Sekine, D. Takahashi, K. Toshima
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 52 Issue: 46 Pages: 12131-12134
- DOI
  10.1002/anie.201304830
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310153, KAKENHI-PUBLICLY-24102528
[Journal Article] Chemical biology based on target-selective degradation of proteins and carbohydarates using light-activable organic molecules2013
- Author(s)
  K. Toshima
- Journal Title
  
  Molecular BioSystems
  
  Volume: 9 Issue: 5 Pages: 834-854
- DOI
  10.1039/c2mb25416f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310153, KAKENHI-PUBLICLY-24102528
[Journal Article] Photodegradation and inhibition of drug-resistant influenza virus neuraminidase using anthraquinone-sialic acid hybrids2013
- Author(s)
  青木優介、谷本周穂、高橋大介、戸嶋一敦
- Journal Title
  
  Chemical Communications
  
  Volume: 49 Issue: 12 Pages: 1169-1171
- DOI
  10.1039/c2cc38742e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J05423, KAKENHI-PROJECT-23310153, KAKENHI-PUBLICLY-24102528
[Journal Article] Design, synthesis and evaluation of a boronic acid based artificial receptor for L-DOPA in aqueous media2013
- Author(s)
  H. Ueno, T. Iwata, N. Koshiba, D. Takahashi, K. Toshima
- Journal Title
  
  Chemical Communications
  
  Volume: 49 Issue: 88 Pages: 10403-10405
- DOI
  10.1039/c3cc45275a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310153, KAKENHI-PUBLICLY-24102528
[Journal Article] Total synthesis of vineomycin B22013
- Author(s)
  S. Kusumi, S. Tomono, S. Okuzawa, E. Kaneko, T. Ueda, K. Sasaki, D. Takahashi, K. Toshima
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 135 Issue: 42 Pages: 15909-15912
- DOI
  10.1021/ja407827n
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310153, KAKENHI-PUBLICLY-24102528, KAKENHI-PROJECT-24750154
[Journal Article] Improved total synthesis of incednam2013
- Author(s)
  A. Takada, K. Uda, T. Ohtani, S. Tsukamoto, D. Takahashi, K. Toshima
- Journal Title
  
  The Journal of Antibiotics
  
  Volume: 66 Issue: 3 Pages: 155-159
- DOI
  10.1038/ja.2013.4
- NAID
  10031163115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310153, KAKENHI-PUBLICLY-24102528
[Journal Article] Target-selective photodegradation of verotoxin-1 and reduction of its cytotoxicity to Vero cells using porphyrin-globotriose hybrids2013
- Author(s)
  A. Okochi, S. Tanimoto, D. Takahashi, K. Toshima
- Journal Title
  
  Chemical Communications
  
  Volume: 49 Issue: 54 Pages: 6027-6029
- DOI
  10.1039/c3cc42957a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310153, KAKENHI-PUBLICLY-24102528
[Journal Article] Creation of novel biofunctional molecules for target-selective photodegradation of proteins and carbohydrates: a synthetic and chemical, biological study for the post-genome era2012
- Author(s)
  K. Toshima, D.Takahashi, S. Tanimoto
- Journal Title
  
  Journal of Synthetic Organic Chemistry
  
  Volume: 70 Pages: 1187-1195
- NAID
  10031131198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310153
[Journal Article] Chemical methods for degradation of target oligosaccharides using designed light-activatable organic molecules2012
- Author(s)
  高橋大介
- Journal Title
  
  Chemical Communications
  
  Volume: 48 Issue: 37 Pages: 4397-4407
- DOI
  10.1039/c2cc17384k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710220, KAKENHI-PROJECT-23310153, KAKENHI-PUBLICLY-24102528
[Journal Article] Creation of novel biofunctional molecules for target-selective photodegradation of proteins and carbohydrates: a synthetic and chemical, biological study for the post-genome era2012
- Author(s)
  K. Toshima, D.Takahashi, S. Tanimoto
- Journal Title
  
  Journal of Synthetic Organic Chemistry
  
  Volume: 70 Pages: 1187-1195
- NAID
  10031131198
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24102528
[Journal Article] Chemical methods for degradation of target proteins using designed light-activatable organic molecules2012
- Author(s)
  谷本周穂、高橋大介、戸崎一敦
- Journal Title
  
  Chemical Communications
  
  Volume: 48 Issue: 62 Pages: 7569-7671
- DOI
  10.1039/c2cc30831b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J05423, KAKENHI-PROJECT-23310153, KAKENHI-PUBLICLY-24102528
[Journal Article] エイズの原因物質を光で狙い撃ち2012
- Author(s)
  谷本周穂、高橋大介、戸嶋一敦
- Journal Title
  
  光アライアンス
  
  Volume: 23 Pages: 50-53
- Data Source
  KAKENHI-PROJECT-23310153
[Journal Article] Creation of novel biofunctional molecules for target-selective photodegradation of proteins and carbohydrates : a synthetic and chemical, biological study for the post-genome era2012
- Author(s)
  K. Toshima, D.Takahashi, S. Tanimoto
- Journal Title
  
  Journal of Synthetic Organic Chemistry
  
  Volume: 70 Pages: 1187-1195
- NAID
  10031131198
- URL
  https://www.jstage.jst.go.jp/article/yukigoseikyokaishi/70/11/70_1187/_pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310153
[Journal Article] Carbohydrate recognition and photodegradation by an anthracene-Kemp's acid hybrid2012
- Author(s)
  M. Nishibu, D. Takahashi, K. Toshima
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 10 Issue: 42 Pages: 8393-8395
- DOI
  10.1039/c2ob26417j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310153, KAKENHI-PUBLICLY-24102528
[Journal Article] エイズの原因物質を光で狙い撃ち2012
- Author(s)
  谷本周穂、高橋大介、戸嶋一敦
- Journal Title
  
  光アライアンス
  
  Volume: 23 Pages: 50-53
- Data Source
  KAKENHI-PUBLICLY-24102528
[Journal Article] Degradation of target oligosaccharides by anthraquinone-lectin hybrids with light switching2012
- Author(s)
  Y. Imai, S. Hirono, H. Matsuba, T. Suzuki, Y. Kobayashi, H. Kawagishi, D. Takahashi, K. Toshima
- Journal Title
  
  Chemistry-An Asian Journal
  
  Volume: 7 Issue: 1 Pages: 97-104
- DOI
  10.1002/asia.201100586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310153, KAKENHI-PUBLICLY-24102513
[Journal Article] Target-selective photodegradation of HIV-1 protease and inhibition of HIV-1 replication in living cells by designed fullerene-sugar hybrids2012
- Author(s)
  谷本周穂
- Journal Title
  
  Chemistry-An Asian Journal
  
  Volume: (掲載確定) Issue: 5 Pages: 911-914
- DOI
  10.1002/asia.201101043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J05423, KAKENHI-PROJECT-23310153, KAKENHI-PUBLICLY-24102528
[Journal Article] Photodegradation of lipopolysaccharides and the inhibition of macrophage activation by anthraquinone-boronic acid hybrids2012
- Author(s)
  D. Takahashi, T. Miura, K. Toshima
- Journal Title
  
  Chemical Communications
  
  Volume: 48 Issue: 61 Pages: 7595-7597
- DOI
  10.1039/c2cc33559j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310153, KAKENHI-PUBLICLY-24102528
[Journal Article] Design, synthesis and evaluation of light-activatable organic molecules that target-selectively degrade DNA, proteins and carbohydrates; an interdisciplinary challenge for a synthetic organic chemist2012
- Author(s)
  K. Toshima
- Journal Title
  
  Synlett
  
  Volume: 23 Issue: 14 Pages: 2025-2052
- DOI
  10.1055/s-0032-1316639
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310153, KAKENHI-PUBLICLY-24102528
[Journal Article] Chemistry Based Approach for Degradation of Target-Oligosaccharides Using Photo-Activatable Organic Small Molecules2012
- Author(s)
  D. Takahashi, K. Toshima
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 24 Issue: 140 Pages: 258-276
- DOI
  10.4052/tigg.24.258
- NAID
  10031146678
- ISSN
  0915-7352, 1883-2113
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310153, KAKENHI-PUBLICLY-24102528
[Journal Article] Target-selective photodegradation of oligosaccharides by a fullerene-boronic acid hybrid upon visible light irradiation2011
- Author(s)
  高橋大介
- Journal Title
  
  Chemical Communications
  
  Volume: 47 Issue: 42 Pages: 11712-11714
- DOI
  10.1039/c1cc15646b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710220, KAKENHI-PROJECT-23310153
[Journal Article] フラーレンのアルツハイマー病治療薬といての可能性2011
- Author(s)
  戸嶋一敦
- Journal Title
  
  バイオインダストリー
  
  Volume: 29 Pages: 7-12
- Data Source
  KAKENHI-PROJECT-23310153
[Journal Article] Molecular design, chemical synthesis, and biological evaluation of agents that selectively photo-degrade the transcription factor estrogen receptor-α2011
- Author(s)
  津村加奈
- Journal Title
  
  Organic & biomolecular Chemistry
  
  Volume: 9 Issue: 18 Pages: 6537-6366
- DOI
  10.1039/c1ob05629h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J05423, KAKENHI-PROJECT-23310153
[Journal Article] Inhibition of amyloid ・aggregation and cytotoxicity by photodegradation using a designed fullerene derivative2011
- Author(s)
  Y. Ishida, T. Fujii, K. Oka, D. Takahashi, K. Toshima
- Journal Title
  
  Chemistry-An Asian Journal
  
  Volume: 6 Issue: 9 Pages: 2312-2315
- DOI
  10.1002/asia.201100421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310153
[Journal Article] フラーレン誘導体を用いたアルツハイマー病原因物質の光分解2011
- Author(s)
  戸嶋一敦
- Journal Title
  
  NEW DIAMOND
  
  Volume: 27 Pages: 24-26
- NAID
  40019173394
- Data Source
  KAKENHI-PROJECT-23310153
[Journal Article] アルツハイマー病の原因物質を光で狙い撃ち2011
- Author(s)
  戸嶋一敦
- Journal Title
  
  光アライアンス
  
  Volume: 22 Pages: 22-25
- Data Source
  KAKENHI-PROJECT-23310153
[Journal Article] Photodegradation of target oligosaccharides by light-activated small molecules2010
- Author(s)
  D.Takahashi, S.Hirono, C.Hayashi, M.Igarashi, Y.Nishimura, K.Toshima
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 49 Pages: 10096-10100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310140
[Journal Article] 標的糖鎖を光分解する生体機能分子の創製2010
- Author(s)
  戸嶋一敦
- Journal Title
  
  バイオインダストリー 27(2)
  
  Pages: 43-48
- Data Source
  KAKENHI-PROJECT-20310140
[Journal Article] 光感受性分子標的薬の創製研究2010
- Author(s)
  戸嶋一敦
- Journal Title
  
  日本発ブロックバスターを目指して-創薬研究の最前線-
  
  Pages: 118-125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310140
[Journal Article] 標的糖鎖を光分解する生体機能分子の創製2010
- Author(s)
  戸嶋一敦
- Journal Title
  
  バイオインダストリー 27
  
  Pages: 43-48
- Data Source
  KAKENHI-PROJECT-20310140
[Journal Article] Photodegradation of target oligosaccharides by light-activated small molecules2010
- Author(s)
  D.Takahashi, S.Hirono, C.Hayashi, M.Igarashi, Y.Nishimura, K.Toshima
- Journal Title
  
  Angew.Chem.Int.Ed. 49
  
  Pages: 10096-10100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310140
[Journal Article] Photo-degradation of amyloid β by a designed fullerene-sugar hybrid2010
- Author(s)
  Y.Ishida, S.Tanimoto, D.Takahashi, K.Toshima
- Journal Title
  
  Medicinal Chemistry Communications
  
  Volume: 1 Pages: 212-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310140
[Journal Article] 新しい分子標的薬とその設計:光感受性分子標的薬2010
- Author(s)
  戸嶋一敦
- Journal Title
  
  腎と透析 67
  
  Pages: 577-582
- Data Source
  KAKENHI-PROJECT-20310140
[Journal Article] 糖鎖を認識する超分子2010
- Author(s)
  高橋大介, 戸嶋一敦
- Journal Title
  
  バイオインダストリー 27
  
  Pages: 12-17
- Data Source
  KAKENHI-PROJECT-20310140
[Journal Article] Photo-degradation of amyloid β by a designed fullerene-sugar hybrid2010
- Author(s)
  Y.Ishida, S.Tanimoto, D.Takahashi, K.Toshima
- Journal Title
  
  Med.Chem.Commun. 1
  
  Pages: 212-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310140
[Journal Article] 糖鎖を認識する超分子2010
- Author(s)
  高橋大介、戸嶋一敦
- Journal Title
  
  バイオインダストリー 27(2)
  
  Pages: 12-17
- Data Source
  KAKENHI-PROJECT-20310140
[Journal Article] 2-フェニルキノリン-ステロイドホルモンハイブリツド分子による標的タンパク選択的光分解と抗細胞活性2009
- Author(s)
  津村加奈, 鈴木あかね, 続木武男, 松村秀一, 梅澤一夫, 戸嶋一敦
- Journal Title
  
  Chemical Biology 2
  
  Pages: 1-4
- Data Source
  KAKENHI-PROJECT-20310140
[Journal Article] Target-selective degradation of cancer-related proteins by novel photo-sensitizers for molecular-targeted photodynamic therapy2009
- Author(s)
  K.Toshima, S.Tanimoto, K.Tsumura, K.Umezawa, D.Takahashi
- Journal Title
  
  Cancer Sci. 100
  
  Pages: 1581-1584
- NAID
  10027194039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310140
[Journal Article] 新しい分子標的薬とその設計 : 光感受性分子標的薬2009
- Author(s)
  戸嶋一敦
- Journal Title
  
  腎と透析 67(5)
  
  Pages: 577-582
- Data Source
  KAKENHI-PROJECT-20310140
[Journal Article] Target-selective degradation of proteins and oligosaccharides by light-activated hybrid molecules for molecular-targeted photodynamic therapy2009
- Author(s)
  戸嶋一敦
- Journal Title
  
  Future Medicinal Chemistry 1
  
  Pages: 1113-1124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310140
[Journal Article] Target-selective degradation of cancer-related proteins by novel photo-sensitizers for molecular-targeted photodynamic therapy2009
- Author(s)
  K.Toshima, S.Tanimoto, K.Tsumura, K.Umezawa, D.Takahashi
- Journal Title
  
  Cancer Science 100
  
  Pages: 1581-1584
- NAID
  10027194039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310140
[Journal Article] 2-フェニルキノリン-ステロイドホルモンハイブリッド分子による標的タンパク選択的光分解と抗細胞活性2009
- Author(s)
  津村加奈、鈴木あかね、続木武男、松村秀一、梅澤一夫、戸嶋一敦
- Journal Title
  
  Chemical Biology 2
  
  Pages: 1-4
- Data Source
  KAKENHI-PROJECT-20310140
[Journal Article] Target-selective degradation of proteins and oligosaccharides by light-activated hybrid molecules for molecular-targeted photodynamic therapy2009
- Author(s)
  戸嶋一敦
- Journal Title
  
  Future Med.Chem. 1
  
  Pages: 1113-1124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310140
[Journal Article] Target-selective photo-degradation of HIV-1 protease by a fullerene-sugar hybrid2008
- Author(s)
  S.Tanimoto, S.Sakai, S.Matsumura, D.Takahashi, K.Toshima
- Journal Title
  
  Chem.Commun.
  
  Pages: 5767-5769
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310140
[Journal Article] Target-selective degradation of proteins by porphyrins upon visible photo-irradiation2008
- Author(s)
  S.Tanimoto, S.Matsumura, K.Toshima
- Journal Title
  
  Chem.Commun.
  
  Pages: 3678-3680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310140
[Journal Article] Target-selective photo-degradation of HIV-1 protease by a fullerene-sugar hybrid2008
- Author(s)
  S. Tanimoto, S. Sakai, S. Matsumura, D. Takahashi, K. Toshima
- Journal Title
  
  Chemical Communications なし
  
  Pages: 5767-5769
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310140
[Journal Article] Target-selective degradation of proteins by porphyrins upon visible photo-irradiation2008
- Author(s)
  S. Tanimoto, S. Matsumura, K. Toshima
- Journal Title
  
  Chemical Communications なし
  
  Pages: 3678-3680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310140
[Journal Article] イオン液体の環境調和型グリコシル化反応への活用2006
- Author(s)
  戸嶋一敦
- Journal Title
  
  ファインケミカル 35・9
  
  Pages: 55-63
- Data Source
  KAKENHI-PROJECT-18032068
[Journal Article] Perspectives for Synthesis and Production of Polyurethanes and Related Polymers by Enzymes Directed Towards Green and Sustainable Chemistry2006
- Author(s)
  S.Matsumura, Y.Soeda, K.Toshima
- Journal Title
  
  Applied Microbiology and Biotechnology 70
  
  Pages: 12-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350095
[Journal Article] New Strategy for Enzymatic Synthesis of High-Molecular-Weight Poly(butylene succinate) via Cyclic Oligomers2006
- Author(s)
  S.Sugihara, K.Toshima, S.Matsumura
- Journal Title
  
  Macromolecular Rapid Communications 27
  
  Pages: 203-207
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350095
[Journal Article] An efficient glycosidation method using 2, 3-unsaturated glycosyl donors2006
- Author(s)
  Sasaki K, Matsumura S, Toshima K
- Journal Title
  
  TETRAHEDRON LETTERS 47(51)
  
  Pages: 9039-9043
- Data Source
  KAKENHI-PROJECT-18639001
[Journal Article] Novel glycosylation methods and their application to natural products synthesis2006
- Author(s)
  Kazunobu Toshima
- Journal Title
  
  Carbohydrate Research 341・10
  
  Pages: 1282-1297
- Data Source
  KAKENHI-PROJECT-18032068
[Journal Article] 糖-インターカレーター複合型人工DNA光切断分子の分子デザインと機能発現制御2005
- Author(s)
  戸嶋一敦
- Journal Title
  
  有機合成化学協会誌 63・4
  
  Pages: 325-338
- NAID
  10015506272
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510180
[Journal Article] Degradation of Poly(lactic acid) into Repolymerizable Oligomer using Montmorillonite K10 for Chemical Recycling2005
- Author(s)
  K.Okambto, K.Toshima, S.Matsumura
- Journal Title
  
  Macromolecular Bioscience 5(9)
  
  Pages: 813-820
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350095
[Journal Article] Preparation of Aliphatic Poly(thioester) by the Lipase-Catalyzed Direct Polycondensation of 11-Mercaptoundecanoic Acid2005
- Author(s)
  M, Kato, K.Toshima, S.Matsumura
- Journal Title
  
  Biomacromolecules 6(4)
  
  Pages: 2275-2280
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350095
[Journal Article] Enzymatic Transformation of Bacterial Polyhydroxyalkanoates into Repolymerizable Oligomers Directed towards Chemical Recycling2005
- Author(s)
  S.Kaihara, Y.Osanai, K.Nishikawa, K.Toshima, Y.Doi, S.Matsumura
- Journal Title
  
  Macromolecular Bioscience 5(7)
  
  Pages: 644-652
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350095
[Journal Article] Enzymatic Synthesis and Chemical Recycling of Poly(ester-urethane)2005
- Author(s)
  Y.Soeda, K.Toshima, S.Matsumura
- Journal Title
  
  Macromolecular Bioscience 5(4)
  
  Pages: 277-288
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350095
[Journal Article] Chemical recycling of Poly(lactic acid) Using Solid Acid (Japanese)2005
- Author(s)
  S.Matsumura, K.Okamoto, K.Toshima
- Journal Title
  
  Fine Chemicals 34(8)
  
  Pages: 20-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350095
[Journal Article] Molecular design, chemical synthesis and biological activity of artificial and DNA photocleaving carbohydrate-Intercalator hybrids.2005
- Author(s)
  K.Toshima
- Journal Title
  
  Journal of Synthetic Organic Chemistry, Japan 63
  
  Pages: 325-338
- NAID
  10015506272
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15510180
[Journal Article] Next Generation-type Green Polyurethane : Enzymatic Synthesis and Chemical Recycling of Poly(ester-urethane) and Poly(ester-urethane)(Japanese)2005
- Author(s)
  Y.Soeda, K.Toshima, S.Matsumura
- Journal Title
  
  Polymer Applications 54(3)
  
  Pages: 29-35
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350095
[Journal Article] Environmentally Benign β-Stereoselective Glycosidations of Glycosyl Phosphites Using a Reusable Heterogeneous Solid Acid, Montmorillonite K-102005
- Author(s)
  H.Nagai, K.Sasaki, S.Matsumura, K.Toshima
- Journal Title
  
  Carbohydrate Research 430
  
  Pages: 337-353
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350095
[Journal Article] Transformation of Biodegradable Polyesters into Cyclic Oligomers under Continuous Flow Using an Enzyme-Packed Column2004
- Author(s)
  Y.Osanai, K.Toshima, S.Matsumura
- Journal Title
  
  Macromolecular Bioscience 4(10)
  
  Pages: 936-942
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350095
[Journal Article] 副作用の少ない新規抗癌剤-DNAをターゲットとした新たな光線力学療法剤-2004
- Author(s)
  戸嶋一敦
- Journal Title
  
  ファインケミカル 33・10
  
  Pages: 28-38
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510180
[Journal Article] The significant effect on the carbohydrate structure on the DNA photocleaving of the quinoxaline-carbohydrate hybrids2004
- Author(s)
  K.Toshima
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 14・11
  
  Pages: 2777-2779
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510180
[Journal Article] Stereocontrolled glycosidations using a heterogeneous solid acid, sulfated zirconia, for the direct syntheses of α- and β-manno- and 2-deoxyglucopyranosides2004
- Author(s)
  K.Toshima, H.Nagai, K.Kasumi, K.Kawahara, S.Matsumura
- Journal Title
  
  Tetrahedron 60(6)
  
  Pages: 5331-5339
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350095
[Journal Article] Molecular design, chemical synthesis and biological evaluation of anthracene-carbohydrate hybrids as novel photocleaving and photoselective cytotoxic agents.2004
- Author(s)
  K.Toshima
- Journal Title
  
  ARKIVOC (13)
  
  Pages: 28-35
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15510180
[Journal Article] Enzymatic Synthesis and Chemical Recycling of Poly(carbonate- urethane)2004
- Author(s)
  Y.Soeda, K.Toshima, S.Matsumura
- Journal Title
  
  Macromolecular Bioscience 4(8)
  
  Pages: 721-728
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350095
[Journal Article] Development of selective antitumor agents : DNA targeted drugs for photodynamic therapy.2004
- Author(s)
  K.Toshima
- Journal Title
  
  Fine Chemicals 33
  
  Pages: 28-38
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15510180
[Journal Article] Molecular design, chemical synthesis and biological evaluation of anthracene-carbohydrate hybrids as novel photocleaving and photoselective cytotoxic agents2004
- Author(s)
  K.Toshima
- Journal Title
  
  ARKIVOC 13
  
  Pages: 28-35
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510180
[Journal Article] The significant effect on the carbohydrate structure on the DNA photocleaving of the quinoxaline-carbohydrate hybrids.2004
- Author(s)
  K.Toshima
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 14
  
  Pages: 2777-2779
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15510180
[Journal Article] Stereocontrolled glycosidations using a heterogeneous solid acid, sulfated zirconia, for the direct syntheses of α-nad β-manno- and 2-deoxyglucopyranosides2004
- Author(s)
  K.Toshima
- Journal Title
  
  Tetrahedron 60(6)
  
  Pages: 5331-5339
- Data Source
  KAKENHI-PROJECT-15350095
[Journal Article] Stereocontrolled glycosidations using a heterogeneous solid acid, sulfated zirconia, for the direct syntheses of α-nad β-manno-and 2-deoxyglucopyranosides2004
- Author(s)
  K.Toshima
- Journal Title
  
  Tetrahedron 60・6
  
  Pages: 5331-5339
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350095
[Journal Article] Novel anthraquinone-carbohydrate hybrids : The significant improvement of the DNA photocleaving activity and the cytotoxic selectivity2004
- Author(s)
  K.Toshima
- Journal Title
  
  Letters in Organic Chemistry 1・1
  
  Pages: 31-34
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510180
[Journal Article] A novel glycosidation of glycosyl fluoride using a designed ionic liquid and its effect on the stereoselectivity2004
- Author(s)
  K.Sasaki, S.Matsumura, K.Toshima
- Journal Title
  
  Tetrahedron Letters 45
  
  Pages: 7043-7047
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350095
[Journal Article] Lipase-Catalyzed Transformation of Poly(lactic acid) into Cyclic Oligomer2004
- Author(s)
  Y.Takahashi, S.Okajima, K.Toshima, S.Matsumura
- Journal Title
  
  Macromolecular Bioscience 4(3)
  
  Pages: 346-353
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350095
[Journal Article] Novel anthraquinone-carbohydrate hybrids : The significant improvement of the DNA photocleaving activity and the cytotoxic selectivity.2004
- Author(s)
  K.Toshima
- Journal Title
  
  Letters in Organic Chemistry 1
  
  Pages: 31-34
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15510180
[Journal Article] Glycidol-carbohydrate hybrids : A new family of DNA alkylating agents2003
- Author(s)
  K.Toshima
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 13・19
  
  Pages: 3281-3283
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510180
[Journal Article] A novel greener glycosidation using an acid-ionic liquid containing a protic acid2003
- Author(s)
  K.Sasaki, H.Nagai, S.Matsumura, K.Toshima
- Journal Title
  
  Tetrahedron Letters 44(30)
  
  Pages: 5605-5608
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350095
[Journal Article] Molecular design, chemical synthesis and biological evaluation of quinaxaline-carbohydrate hybrids as novel and selective photo-induced DNA cleaving and cytotoxic agents.2003
- Author(s)
  K.Toshima
- Journal Title
  
  Tetrahedron 59
  
  Pages: 7057-7066
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15510180
[Journal Article] Glycidol-carbonydrate Hybrids : A new family of DNA alkylating agents.2003
- Author(s)
  K.Toshima
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 13
  
  Pages: 3281-3283
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15510180
[Journal Article] Molecular design, chemical synthesis, and biological evaluation of novel anthraquinone-carbohydrate hybrids as photo-induced DNA cleaving and cytotoxic agents.2003
- Author(s)
  K.Toshima
- Journal Title
  
  Trends in Organic Chemistry (10)
  
  Pages: 113-117
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15510180
[Journal Article] Environmentally benign and stereoselective formation of β-mannosidic linkages utilizing 2,3-di-O-benzyl-4,6-O-benzylidene-protected mannopyranosyl phosphite and montmorillonite K-102003
- Author(s)
  H.Nagai, S.Matsumura, K.Toshima
- Journal Title
  
  Carbohydrate Research 338(15)
  
  Pages: 1531-1534
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350095
[Journal Article] Lipase- Catalyzed Transformation of Poly(butylene adipate) and Poly(butylene succinate) into Repolymerizable Cyclic Oligomers2003
- Author(s)
  S.Okajima, R.Kondo, K.Toshima, S.Matsumura
- Journal Title
  
  Biomacromolecules 4(6)
  
  Pages: 1514-1519
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350095
[Journal Article] Enzyme-Catalyzed Preparation of Aliphatic Polyesters Containing Thioester Linkages2003
- Author(s)
  S.Iwata, K.Toshima, S.Matsumura
- Journal Title
  
  Macromolecular Rapid Communications 24(7)
  
  Pages: 467-471
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350095
[Journal Article] Molecular design, chemical synthesis, and biological evaluation of quinaxaline-carbohydrate hybrids as novel and selective photo-induced DNA cleaving and cytotoxic agents2003
- Author(s)
  K.Toshima
- Journal Title
  
  Tetrahedron 59・35
  
  Pages: 7057-7066
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510180
[Journal Article] Enzymatic Degradation of Poly(3-hydroxybutyrate) to Cyclic Oligomers under Continuous Flow2003
- Author(s)
  Y.Osanai, K.Toshima, S.Matsumura
- Journal Title
  
  Green Chemistry 5(5)
  
  Pages: 567-570
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350095
[Journal Article] Molecular design, chemical synthesis, and biological evaluation of novel anthraquinone-carbohydrate hybrids as photo-induced DNA cleaving and cytotoxic agents2003
- Author(s)
  K.Toshima
- Journal Title
  
  Trends in Organic Chemistry 10
  
  Pages: 113-117
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510180
[Journal Article] 糖-インターカレーター複合型人工DNA光切断分子の分子デザインと機能発現制御
- Author(s)
  戸嶋一敦
- Journal Title
  
  有機合成化学協会誌 (印刷中)
- NAID
  10015506272
- Data Source
  KAKENHI-PROJECT-15510180
[Patent] 光増感剤,タンパク質切断剤,タンパク質切断方法,糖分子切断剤,糖分子切断方法,及び光線力学的治療剤2012
- Inventor(s)
  戸嶋一敦
- Industrial Property Rights Holder
  学校法人慶應義塾
- Industrial Property Rights Type
  特許
- Acquisition Date
  2012-07-27
- Data Source
  KAKENHI-PROJECT-23310153
[Patent] ノイラミダーゼに対する酵素阻害剤2010
- Inventor(s)
  戸嶋一敦、高橋大介、青木優介
- Industrial Property Rights Holder
  清家篤
- Filing Date
  2010-02-03
- Data Source
  KAKENHI-PROJECT-20310140
[Patent] ノイラミニダーゼに対する酵素阻害剤2010
- Inventor(s)
  戸嶋一敦, 高橋大介, 青木優
- Industrial Property Rights Holder
  清家篤
- Industrial Property Number
  2010-022168
- Filing Date
  2010-02-03
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] エンジイン系抗生物質N1999A2を基本骨格としたがん細胞応答型光感受性分子の創製2024
- Author(s)
  加賀谷つぐみ、高橋南美、松永ことの、高橋大介、戸嶋一敦
- Organizer
  日本化学会第104春季年会
- Data Source
  KAKENHI-PROJECT-23K23479
[Presentation] セラノスティクスを指向したがん細胞応答型光感受性分子―蛍光分子ハイブリッドの創製2024
- Author(s)
  松永ことの、髙橋南美、加賀谷つぐみ、高橋大介、戸嶋一敦
- Organizer
  日本化学会第104春季年会
- Data Source
  KAKENHI-PROJECT-23K23479
[Presentation] ヒポクレリンBを基本骨格としたがん細胞応答型光感受性分子の創製2023
- Author(s)
  石田文久、大西陸人、高橋大介、戸嶋一敦
- Organizer
  第 1７回ケミカルバイオロジー学会
- Data Source
  KAKENHI-PROJECT-23K23479
[Presentation] アントラノールを基本骨格とする刺激応答型光感受性分子の発見とがん細胞応答型光感受性分子の創製2023
- Author(s)
  李瑜莎、増田侑希、高橋大介、戸嶋一敦
- Organizer
  第 1７回ケミカルバイオロジー学会
- Data Source
  KAKENHI-PROJECT-23K23479
[Presentation] エンジイン系抗生物質N1999A2のナフトール構造を基本骨格とした新規光感受性分子の創製2023
- Author(s)
  髙橋南美、松永ことの、加賀谷つぐみ、高橋大介、戸嶋一敦
- Organizer
  日本化学会第103春季年会
- Data Source
  KAKENHI-PROJECT-23K23479
[Presentation] エンジイン系抗生物質のナフトール誘導体によるタンパク質光分解および光細胞毒性に関する研究2022
- Author(s)
  髙橋南美、松永ことの、北村貴士、高橋大介、戸嶋一敦
- Organizer
  第 16 回ケミカルバイオロジー学会
- Data Source
  KAKENHI-PROJECT-23K23479
[Presentation] 無保護の天然配糖体に対するボロン酸触媒を用いた直接的な位置及び1,2-cis-立体選択的グリコシル化反応の開発2018
- Author(s)
  吉田亮毅、田中将道、高橋大介、戸嶋一敦
- Organizer
  日本化学会第９８春季年会
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Presentation] 抗生物質ビネオマイシンA1の全合成2018
- Author(s)
  栗木甫、松本優香、舩越桃子、菅野優子、小林巧、高橋大介、戸嶋一敦
- Organizer
  日本化学会第９８春季年会
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Presentation] 光感受性分子―糖ハイブリッドによるα―グルコシダーゼの選択的光分解と酵素阻害活性2018
- Author(s)
  高橋大介、奥山真衣、北村貴士、戸嶋一敦
- Organizer
  新学術領域研究「反応集積化が導く中分子戦略：高次生物機能分子の創製」第5回公開成果報告会
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Presentation] マンノシルエリスリトールリピッド類(MELs)の系統的合成とベシクル形成に与える効果2018
- Author(s)
  梨子田淳希、西信哉、伴野太祐、朝倉浩一、高橋大介、戸嶋一敦
- Organizer
  日本化学会第９８春季年会
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Presentation] フコイダン類縁体の系統的合成とがん関連酵素ヘパラナーゼ選択的阻害活性2018
- Author(s)
  小薗脩平、駒場澄香、高橋大介、戸嶋一敦
- Organizer
  日本化学会第９８春季年会
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Presentation] 芳香族ジスルフィドを光触媒に用いた環境調和型光グリコシル化反応の開発2018
- Author(s)
  江藤貴宏、栗波怜史、青柳学、高橋大介、戸嶋一敦
- Organizer
  日本化学会第９８春季年会
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Presentation] ネオカルチノスタチン・クロモフォアの芳香環部位によるタンパク質の光分解2018
- Author(s)
  北村貴士、高橋大介、戸嶋一敦
- Organizer
  日本化学会第９８春季年会
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Presentation] ボリン酸―糖受容体エステルを用いた立体選択的β-ラムノシル化反応の開発2018
- Author(s)
  末岡和博、西信哉、高橋大介、戸嶋一敦
- Organizer
  日本化学会第９８春季年会
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Presentation] 還元糖を選択的に光分解するアントラキノン-ヒドラジドハイブリッドの創製とAGEs生成阻害への応用2017
- Author(s)
  高城美智、高橋大介、戸嶋一敦
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  慶應義塾大学（神奈川県、横浜市）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-26282212
[Presentation] 還元糖を選択的に光分解するアントラキノン-ヒドラジドハイブリッドの創製とAGEs生成阻害への応用2017
- Author(s)
  高城美智、高橋大介、戸嶋一敦
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  慶應義塾大学（神奈川県、横浜市）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Presentation] Synthetic Studies on an Antibiotic, Vineomycin A12017
- Author(s)
  Hajime Kuriki, Yuka Matsumoto, Takumi Kobayashi, Harunobu Nakayama, Shunichi Kusumi, Daisuke Takahashi, Kazunobu Toshima
- Organizer
  5th National Tsing Hua University / Keio University Bilateral Symposium of Advanced Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Presentation] 光感受性分子-糖ハイブリッドによるグリコシダーゼの選択的光分解2017
- Author(s)
  奥山真衣、高橋大介、戸嶋一敦
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  慶應義塾大学（神奈川県、横浜市）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Presentation] 光感受性分子-糖ハイブリッドによるグリコシダーゼの選択的光分解2017
- Author(s)
  奥山真衣、高橋大介、戸嶋一敦
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  應義塾大学（神奈川県、横浜市）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-26282212
[Presentation] 機能複合化による生体機能光制御中分子の創製2017
- Author(s)
  戸嶋一敦
- Organizer
  新学術領域研究「反応集積化が導く中分子戦略高次生物機能分子の創製」第3回公開成果報告会
- Place of Presentation
  早稲田大学（東京都、新宿区）
- Year and Date
  2017-01-28
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Presentation] 機能複合化による生体機能光制御中分子の創製　～セラノスティクスを指向したH2O2応答型蛍光分子―光感受性分子ハイブリッドの創製～2017
- Author(s)
  高橋大介、戸嶋一敦
- Organizer
  新学術領域研究「反応集積化が導く中分子戦略：高次生物機能分子の創製」第4回公開成果報告会
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Presentation] 硫酸化オリゴフコシドの系統的合成とインフルエンザウイルス感染に対する効果2017
- Author(s)
  高橋大介、笠井章弘、小薗脩平、松原輝彦、佐藤智典、戸嶋一敦
- Organizer
  第３６回日本糖質学会年会
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Presentation] Development and Application of Boronic Acid Catalyzed Regio- and 1,2-cis-Stereoselective Glycosylation of Unprotected Sugar Acceptors2017
- Author(s)
  Daisuke Takahashi, Masamichi Tanaka, Akira Nakagawa, Nobuya Nishi, Kazunobu Toshima
- Organizer
  9th Asian Community of Glycoscience and Glycotechnology Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Presentation] ボロン酸触媒を用いた位置及び立体選択的1,2-cis-β-グリコシル化反応の開発2017
- Author(s)
  西信哉、梨子田淳希、梶英輔、高橋大介、戸嶋一敦
- Organizer
  第３６回日本糖質学会年会
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Presentation] セラノスティクスを指向したROS応答型蛍光分子-光感受性分子ハイブリッドの合成と機能評価2017
- Author(s)
  高木亮馬、高橋大介、戸嶋一敦
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  慶應義塾大学（神奈川県、横浜市）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Presentation] Development and Application of Boronic Acid Catalyzed Regio- and Stereoselective β-Mannosylation2017
- Author(s)
  Nobuya Nishi, Junki Nashida, Eisuke Kaji, Daisuke Takahashi, Kazunobu Toshima
- Organizer
  The 11th International Symposium on Integrated Synthesis (ISONIS-11) & The 3rd International Symposium on Middle Molecular Strategy (ISMMS-3)
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Presentation] Boronic Acid Catalyzed Regio- and 1,2-cis-α-Stereoselective Glycosylation of Unprotected Sugar BAcceptors and Its Application to the Synthesis of Biologically Active Glycosides2017
- Author(s)
  Daisuke Takahashi, Masamichi Tanaka, Akira Nakagawa, Kazunobu Toshima
- Organizer
  The 13th Yonsei CBMH - Keio LCC Joint Symposium 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Presentation] セラノスティクスを指向したROS応答型蛍光分子-光感受性分子ハイブリッドの合成と機能評価2017
- Author(s)
  高木亮馬、高橋大介、戸嶋一敦
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  應義塾大学（神奈川県、横浜市）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-26282212
[Presentation] Target-selective Photo-Degradation of AFP-L3 and Selective Photo-Cytotoxicity Against HuH-7 Hepatocarcinoma Cells Using An Anthraquinone-PhoSL Hybrid2016
- Author(s)
  M. Okuyama, H. Ueno, Y. Kobayashi, H. Kawagishi, D. Takahashi, K. Toshima
- Organizer
  4th National Tsing Hua University / Keio University Bilateral Symposium of Advanced Chemistry
- Place of Presentation
  慶應義塾大学（神奈川県、横浜市）
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Presentation] アントラキノン-ヒドラジドハイブリッドによる還元糖の選択的光分解とAGEs 生成阻害への応用2016
- Author(s)
  高城美智、高橋大介、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第11 回年会
- Place of Presentation
  京都テルサ（京都府、京都市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Presentation] 光制御型酵素を指向したアントラキノン-酵素-ペプチドハイブリッド分子の創製2016
- Author(s)
  外川翔太、高橋大介、戸嶋一敦
- Organizer
  日本化学会第96 春季年会
- Place of Presentation
  同志社大学京田辺キャンパス(京都府・京田辺市)
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-26282212
[Presentation] 硫酸化オリゴフコシドの系統的合成とインフルエンザウイルスヘマグルチニンに対する結合能2016
- Author(s)
  笠井章弘、荒深慎介、松原輝彦、佐藤智典、高橋大介、戸嶋一敦
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  同志社大学京田辺キャンパス(京都府・京田辺市)
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PUBLICLY-26102738
[Presentation] Target-selective Photo-Degradation of AFP-L3 and Selective Photo-Cytotoxicity Against HuH-7 Hepatocarcinoma Cells Using An Anthraquinone-PhoSL Hybrid2016
- Author(s)
  M. Okuyama, H. Ueno, Y. Kobayashi, H. Kawagishi, D. Takahashi, K. Toshima
- Organizer
  4th National Tsing Hua University / Keio University Bilateral Symposium of Advanced Chemistry
- Place of Presentation
  慶應義塾大学（神奈川県、横浜市）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26282212
[Presentation] 光制御型酵素を指向したアントラキノン-酵素-ペプチドベクターハイブリッド分子の創製2016
- Author(s)
  外川翔太、高橋大介、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第11 回年会
- Place of Presentation
  京都テルサ（京都府、京都市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-26282212
[Presentation] 光制御型酵素を指向したアントラキノン-酵素-ペプチドベクターハイブリッド分子の創製2016
- Author(s)
  外川翔太、高橋大介、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第11 回年会
- Place of Presentation
  京都テルサ（京都府、京都市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Presentation] 光制御型酵素を指向したアントラキノン-酵素-ペプチドハイブリッド分子の創製2016
- Author(s)
  外川翔太、高橋大介、戸嶋一敦
- Organizer
  日本化学会第96 春季年会
- Place of Presentation
  同志社大学京田辺キャンパス(京都府・京田辺市)
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PUBLICLY-26102738
[Presentation] New Glycosylation Method Using Glycosyl-Acceptor-Derived Boronic Ester Catalyst and lts Application to Total Synthesis of a Natural Product2016
- Author(s)
  D. Takahashi, M. Tanaka, K. Toshima
- Organizer
  The 12th Keio LCC - Yonsei CBMH Joint Symposium
- Place of Presentation
  慶應義塾大学（神奈川県、横浜市）
- Year and Date
  2016-10-21
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01161
[Presentation] アントラキノン-ヒドラジドハイブリッドによる還元糖の選択的光分解とAGEs 生成阻害への応用2016
- Author(s)
  高城美智、高橋大介、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第11 回年会
- Place of Presentation
  京都テルサ（京都府、京都市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-26282212
[Presentation] アントラキノン-PhoSLハイブリッド分子による肝がん関連糖タンパクAFP-L3の光分解及びヒト肝がん細胞HuH-7に対する効果2015
- Author(s)
  上野晴菜、小林夕香、河岸洋和、高橋大介、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第10 回年会
- Place of Presentation
  東北大学川内キャンパス(宮城県・仙台市)
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PUBLICLY-26102738
[Presentation] 天然フコイダンの主鎖を基本構造とした硫酸化オリゴフコシドの系統的合成と構造活性相関研究2015
- Author(s)
  笠井章弘、荒深慎介、小柴望実、高橋大介、戸嶋一敦
- Organizer
  GlycoTOKYO 2015シンポジウム
- Place of Presentation
  慶應義塾大学矢上キャンパス(神奈川県・横浜市)
- Year and Date
  2015-12-15
- Data Source
  KAKENHI-PUBLICLY-26102738
[Presentation] アントラキノン-糖ヌクレオチドハイブリッドによる糖転移酵素の光分解2015
- Author(s)
  増田奏衣、高橋大介、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第10 回年会
- Place of Presentation
  東北大学川内キャンパス(宮城県・仙台市)
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-26282212
[Presentation] Target-selective photodegradation of oilgosaccharides in health and disease2015
- Author(s)
  K. Toshima
- Organizer
  The 2015 International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu, ( USA)
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102738
[Presentation] Target-selective photodegradation of oilgosaccharides in health and disease2015
- Author(s)
  K. Toshima
- Organizer
  The 2015 International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu, ( USA)
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26282212
[Presentation] アントラキノン-糖ヌクレオチドハイブリッドによる糖転移酵素の光分解2015
- Author(s)
  増田奏衣、高橋大介、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第10 回年会
- Place of Presentation
  東北大学川内キャンパス(宮城県・仙台市)
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PUBLICLY-26102738
[Presentation] Target-selective photodegradation of proteins in chemical biology2015
- Author(s)
  K. Toshima
- Organizer
  The 2015 International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu, ( USA)
- Year and Date
  2015-12-15
- Data Source
  KAKENHI-PUBLICLY-26102738
[Presentation] 肝がん関連糖タンパクAFP-L3を選択的に光分解するアントラキノン-PhoSL ハイブリッドの創製と肝がん細胞に対する効果2015
- Author(s)
  奥山真衣、上野晴菜、小林夕香、河岸洋和、高橋大介、戸嶋一敦
- Organizer
  GlycoTOKYO 2015シンポジウム
- Place of Presentation
  慶應義塾大学矢上キャンパス(神奈川県・横浜市)
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PROJECT-26282212
[Presentation] 肝がん関連糖タンパクAFP-L3を選択的に光分解するアントラキノン-PhoSLハイブリッドの創製と肝がん細胞に対する効果2015
- Author(s)
  奥山真衣、上野晴菜、小林夕香、河岸洋和、高橋大介、戸嶋一敦
- Organizer
  GlycoTOKYO 2015シンポジウム
- Place of Presentation
  慶應義塾大学矢上キャンパス(神奈川県・横浜市)
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PUBLICLY-26102738
[Presentation] Target-selective photodegradation of proteins in chemical biology, The 2015 International Chemical Congress of Pacific Basin Societies2015
- Author(s)
  K. Toshima
- Organizer
  Target-selective photodegradation of proteins in chemical biology, The 2015 International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu, ( USA)
- Year and Date
  2015-12-15
- Data Source
  KAKENHI-PROJECT-26282212
[Presentation] アントラキノン-PhoSLハイブリッド分子による肝がん関連糖タンパクAFP-L3の光分解及びヒト肝がん細胞HuH-7に対する効果2015
- Author(s)
  上野晴菜、小林夕香、河岸洋和、高橋大介、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第10 回年会
- Place of Presentation
  東北大学川内キャンパス(宮城県・仙台市)
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-26282212
[Presentation] インドールアルカロイド系天然物セロトニンおよびハルミンによるタンパクの光分解2014
- Author(s)
  村田誠治, 増田奏衣, 高橋大介, 戸嶋一敦
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学東山キャンパス
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Recent topics on synthetic and chemical biological studies of biofunctional molecules2014
- Author(s)
  K. Toshima
- Organizer
  The 2nd Mini-Symposium on Cutting-Edge Chemistry between Keio University and National Tsing Hua University
- Place of Presentation
  MXIC Building, Hsinchu, Taiwan
- Year and Date
  2014-03-13
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] インドールアルカロイド系天然物セロトニンおよびハルミンによるタンパクの光分解2014
- Author(s)
  村田誠治、増田奏衣、高橋大介、戸嶋一敦
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Recent topics on synthetic and chemical biological studies of biofunctional molecules2014
- Author(s)
  K. Toshima
- Organizer
  The 2nd Mini-Symposium on Cutting-Edge Chemistry between Keio University and National Tsing Hua University
- Place of Presentation
  国立精華大学（台湾）
- Data Source
  KAKENHI-PUBLICLY-24102528
[Presentation] 神経伝達物質L-DOPAを選択的に認識するボロン酸含有人工低分子レセプターの創製2014
- Author(s)
  上野晴菜、岩田崇志、小柴望実、高橋大介、戸嶋一敦
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学
- Data Source
  KAKENHI-PUBLICLY-24102528
[Presentation] Recent topics on synthetic and chemical biological studies of biofunctional molecules2014
- Author(s)
  K. Toshima
- Organizer
  The 2nd Mini-Symposium on Cutting-Edge Chemistry between Keio University and National Tsing Hua University
- Place of Presentation
  国立精華大学（台湾）
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] インドールアルカロイド系天然物セロトニンおよびハルミンによるタンパクの光分解2014
- Author(s)
  村田誠治、増田奏衣、高橋大介、戸嶋一敦
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学
- Data Source
  KAKENHI-PUBLICLY-24102528
[Presentation] 神経伝達物質L-DOPA を選択的に認識するボロン酸含有人工低分子レセプターの創製2014
- Author(s)
  上野晴菜, 岩田崇志, 小柴望実, 高橋大介, 戸嶋一敦
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学東山キャンパス
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] アントラセン-シクロデキストリンハイブリッドによる単糖の選択的光分解2014
- Author(s)
  宮崎友紀恵、西部美幸希、高橋大介、戸嶋一敦
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] アントラセン-シクロデキストリンハイブリッドによる単糖の選択的光分解2014
- Author(s)
  宮崎友紀恵、西部美幸希、高橋大介、戸嶋一敦
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学
- Data Source
  KAKENHI-PUBLICLY-24102528
[Presentation] アントラセン-シクロデキストリンハイブリッドによる単糖の選択的光分解2014
- Author(s)
  宮崎友紀恵, 西部美幸希, 高橋大介, 戸嶋一敦
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学東山キャンパス
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] 神経伝達物質L-DOPAを選択的に認識するボロン酸含有人工低分子レセプターの創製2014
- Author(s)
  上野晴菜、岩田崇志、小柴望実、高橋大介、戸嶋一敦
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] ポルフィリン誘導体によるアミロイドβの光分解と神経様細胞PC12に対する効果2013
- Author(s)
  平林歩、高橋大介、戸嶋一敦
- Organizer
  日本化学会第93春季年会
- Place of Presentation
  立命館大学
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Chemical glycosylation with recognition of alcohol chirality2013
- Author(s)
  K. Toshima
- Organizer
  International Symposium on Organic Reaction - 11
- Place of Presentation
  台北（台湾）
- Invited
- Data Source
  KAKENHI-PUBLICLY-24102528
[Presentation] Target-selective photo-degradation of verotoxin-1 and reduction of its cytotoxicity to Vero cells using porphyrin-globotriose hybrids2013
- Author(s)
  K. Toshima
- Organizer
  The 2nd International Symposium on Chemical Biology of Natural Products : Target ID and Regulation of Bioactivity
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PUBLICLY-24102528
[Presentation] Target-selective photo-degradation of verotoxin-1 and reduction of its cytotoxicity to Vero cells using porphyrin-globotriose hybrids2013
- Author(s)
  K. Toshima
- Organizer
  The 2nd International Symposium on Chemical Biology of Natural Products : Target ID and Regulation of Bioactivity
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] ポルフィリン-グロボトリオース(Gb3)ハイブリッドによる大腸菌O‐157ベロ毒素の選択的光分解2013
- Author(s)
  大河内敦, 谷本周穂 ,高橋大介, 戸嶋一敦
- Organizer
  日本化学会第93春季年会
- Place of Presentation
  立命館大学びわこ・くさつキャンパス
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] ポルフィリン－グロボトリオース(Gb3)ハイブリッドによる大腸菌O‐157ベロ毒素の選択的光分解2013
- Author(s)
  大河内敦、谷本周穂、高橋大介、戸嶋一敦
- Organizer
  日本化学会第93春季年会
- Place of Presentation
  立命館大学
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-PUBLICLY-24102528
[Presentation] Chemical glycosylation with recognition of alcohol chirality and its application to natural product synthesis2013
- Author(s)
  K. Toshima
- Organizer
  The 9th Yonsei CBMH - Keio LCC Joint Symposium
- Place of Presentation
  延世大学（韓国）
- Data Source
  KAKENHI-PUBLICLY-24102528
[Presentation] 神経伝達物質L-DOPAを選択的に認識する人工低分子レセプターの創製2013
- Author(s)
  上野晴菜, 岩田崇志, 高橋大介, 戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第8回年会
- Place of Presentation
  東京医科歯科大学M&Dタワー
- Year and Date
  2013-06-20
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Photodegradation and inhibition of drug-resistant influenza virus neuraminidase using anthraquinone-sialic acid hybrids2013
- Author(s)
  K. Toshima
- Organizer
  The 15th Asian Chemical Congress
- Place of Presentation
  Resorts World Sentosa Singapore, Singapore
- Year and Date
  2013-08-22
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Chemical glycosylation with recognition of alcohol chirality2013
- Author(s)
  K. Toshima
- Organizer
  International Symposium on Organic Reaction - 11
- Place of Presentation
  台北（台湾）
- Invited
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] ピロロキノリンキノンによるDNA光分解及びA431細胞に対する効果2013
- Author(s)
  蓮見貴大、高橋大介、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第8回年会
- Place of Presentation
  東京医科歯科大学
- Data Source
  KAKENHI-PUBLICLY-24102528
[Presentation] ピロロキノリンキノンによるDNA 光分解及びA431 細胞に対する効果2013
- Author(s)
  蓮見貴大, 高橋大介, 戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第8回年会
- Place of Presentation
  東京医科歯科大学M&Dタワー
- Year and Date
  2013-06-20
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] 神経伝達物質L-DOPAを選択的に認識する人工低分子レセプターの創製2013
- Author(s)
  上野晴菜、岩田崇志、高橋大介、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第8回年会
- Place of Presentation
  東京医科歯科大学
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] グリコシル化反応の新たな可能性と配糖型天然物の全合成2013
- Author(s)
  戸嶋一敦
- Organizer
  第32回日本糖質学会年会
- Place of Presentation
  大阪国際交流センター
- Invited
- Data Source
  KAKENHI-PUBLICLY-24102528
[Presentation] Photodegradation and inhibition of drug-resistant influenza virus neuraminidase using anthraquinone-sialic acid hybrids2013
- Author(s)
  K. Toshima
- Organizer
  The 15th Asian Chemical Congress
- Place of Presentation
  セントーサ島（シンガポール）
- Invited
- Data Source
  KAKENHI-PUBLICLY-24102528
[Presentation] Chemical glycosylation with recognition of alcohol chirality and its application to natural product synthesis2013
- Author(s)
  K. Toshima
- Organizer
  The 9th Yonsei CBMH - Keio LCC Joint Symposium, Yonsei University
- Place of Presentation
  延世大学（韓国）
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] ピロロキノリンキノンによるDNA光分解及びA431細胞に対する効果2013
- Author(s)
  蓮見貴大、高橋大介、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第8回年会
- Place of Presentation
  東京医科歯科大学
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] アントラキノン－シアル酸ハイブリッドによる薬剤耐性型インフルエンザ・ノイラミニダーゼの光分解と酵素活性阻害2013
- Author(s)
  戸嶋一敦
- Organizer
  新学術領域研究(研究領域提案型)天然物ケミカルバイオロジー～分子標的と活性制御～第4回公開シンポジウム
- Place of Presentation
  つくば国際会議場
- Data Source
  KAKENHI-PUBLICLY-24102528
[Presentation] Photodegradation and inhibition of drug-resistant influenza virus neuraminidase using anthraquinone-sialic acid hybrids2013
- Author(s)
  K. Toshima
- Organizer
  The 15th Asian Chemical Congress
- Place of Presentation
  セントーサ島（シンガポール）
- Invited
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] ポルフィリン－グロボトリオース(Gb3)ハイブリッドによる大腸菌O‐157ベロ毒素の選択的光分解2013
- Author(s)
  大河内敦、谷本周穂、高橋大介、戸嶋一敦
- Organizer
  日本化学会第93春季年会
- Place of Presentation
  立命館大学
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] ポルフィリン誘導体によるアミロイドβの光分解と神経様細胞PC12 に対する効果2013
- Author(s)
  平林歩, 高橋大介, 戸嶋一敦
- Organizer
  日本化学会第93春季年会
- Place of Presentation
  立命館大学びわこ・くさつキャンパス
- Year and Date
  2013-03-25
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] 神経伝達物質L-DOPAを選択的に認識する人工低分子レセプターの創製2013
- Author(s)
  上野晴菜、岩田崇志、高橋大介、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第8回年会
- Place of Presentation
  東京医科歯科大学
- Data Source
  KAKENHI-PUBLICLY-24102528
[Presentation] ポルフィリン誘導体によるアミロイドβの光分解と神経様細胞PC12に対する効果2013
- Author(s)
  平林歩、高橋大介、戸嶋一敦
- Organizer
  日本化学会第93春季年会
- Place of Presentation
  立命館大学
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-PUBLICLY-24102528
[Presentation] アントラキノン-ボロン酸ハイブリッド分子によるLPS の光分解とマクロファージ活性化抑制2012
- Author(s)
  三浦拓也, 高橋大介, 戸嶋一敦
- Organizer
  日本化学会第92 春季年会
- Place of Presentation
  慶應義塾大学
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Photodegradation of target glycolipid LPS and inhibition of macrophage activation by anthraquinone-boronic acid hybrids2012
- Author(s)
  D. Takahashi, T. Miura, K. Toshima
- Organizer
  26 International Carbohydrate Symposium
- Place of Presentation
  マドリード(スペイン)
- Year and Date
  2012-07-22
- Data Source
  KAKENHI-PUBLICLY-24102528
[Presentation] フラーレン誘導体によるHIV-1 プロテアーゼの選択的光分解とHIV 感染細胞におけるウィルス増殖抑制効果2012
- Author(s)
  谷本周穂, 工藤恵理子 ,岡田誠治, 高橋大介, 戸嶋一敦
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶應義塾大学
- Year and Date
  2012-03-26
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] フラーレン誘導体によるHIV-1プロテアーゼの選択的光分解とHIV感染細胞におけるウィルス増殖抑制効果2012
- Author(s)
  谷本周穂、工藤恵理子、岡田誠治、高橋大介、戸嶋一敦
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶應義塾大学
- Year and Date
  2012-03-26
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Photodegradation of drug-resistant influenza virus neuraminidase using designed anthraquinone-sialic acid hybrids2012
- Author(s)
  K. Toshima, Y. Aoki, D. Takahashi
- Organizer
  The 12th International Kyoto Conference on New Aspects of Organic Chemistry
- Place of Presentation
  リーガロイヤルホテル京都
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] リガンドタンパク-アントラキノンハイブリッドによるレセプタータンパクの選択的光分解2012
- Author(s)
  小沼雄介, 高橋大介, 戸嶋一敦
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶應義塾大学
- Year and Date
  2012-03-26
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] アントラセン-ケンプ酸ハイブリッドによる単糖の認識と光分解2012
- Author(s)
  西部美幸希, 高橋大介, 戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第7回年会
- Place of Presentation
  京都大学百周年時計台記念館
- Year and Date
  2012-06-07
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Photodegradation of target glycolipid LPS and inhibition of macrophage activation by anthraquinone-boronic acid hybrids2012
- Author(s)
  D. Takahashi, T. Miura, K. Toshima
- Organizer
  26 International Carbohydrate Symposium
- Place of Presentation
  マドリード(スペイン)
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] アントラキノン-ボロン酸ハイブリッド分子によるLPSの光分解とマクロファージ活性化抑制2012
- Author(s)
  三浦拓也、高橋大介、戸嶋一敦
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶應義塾大学
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Light-activable and molecular-targeted (LAMTA) molecules for control of biomacromolecule functions2012
- Author(s)
  K. Toshima
- Organizer
  The 1st International Symposium on Chemical Biology of Natural Products : Target ID and Regulation of Bioactivity
- Place of Presentation
  京都センチュリーホテル
- Year and Date
  2012-10-31
- Data Source
  KAKENHI-PUBLICLY-24102528
[Presentation] ポルフィリン誘導体によるアミロイドβの光分解2012
- Author(s)
  平林歩、高橋大介、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第7回年会
- Place of Presentation
  京都大学
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Target-selective photo-degradation of HIV-1 protease and inhibition of HIV-1 replication in living cells by a fullerene-sugar hybrid2012
- Author(s)
  S. Tanimoto, D. Takahashi, K. Toshima
- Organizer
  26 International Carbohydrate Symposium
- Place of Presentation
  マドリード(スペイン)
- Year and Date
  2012-07-22
- Data Source
  KAKENHI-PUBLICLY-24102528
[Presentation] Photodegradation of glycolipid LPS and inhibition of macrophage activation using designed anthraquinone-boronic acid hybrids2012
- Author(s)
  K. Toshima
- Organizer
  17th Malaysian Chemical Congress 2012
- Place of Presentation
  クアラルンプール(マレーシア)
- Invited
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Photodegradation of glycolipid LPS and inhibition of macrophage activation using designed anthraquinone-boronic acid hybrids2012
- Author(s)
  K. Toshima
- Organizer
  17th Malaysian Chemical Congress 2012
- Place of Presentation
  クアラルンプール(マレーシア)
- Year and Date
  2012-10-15
- Invited
- Data Source
  KAKENHI-PUBLICLY-24102528
[Presentation] Photodegradation of drug-resistant influenza virus neuraminidase using designed anthraquinone-sialic acid hybrids2012
- Author(s)
  K. Toshima, Y. Aoki, D. Takahashi
- Organizer
  The 12th International Kyoto Conference on New Aspects of Organic Chemistry
- Place of Presentation
  Rihga Royal Hotel KYOTO, Kyoto
- Year and Date
  2012-11-15
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Target-selective photo-degradation of HIV-1 protease and inhibition of HIV-1 replication in living cells by a fullerene-sugar hybrid2012
- Author(s)
  S. Tanimoto, D. Takahashi, K. Toshima
- Organizer
  26 International Carbohydrate Symposium
- Place of Presentation
  Madrid, Spain
- Year and Date
  2012-07-26
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] ポルフィリン誘導体によるアミロイドβ の光分解2012
- Author(s)
  平林歩 ,高橋大介, 戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第7回年会
- Place of Presentation
  京都大学百周年時計台記念館
- Year and Date
  2012-06-07
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] 生体機能光制御分子の創製とケミカルバイオロジーへの展開2012
- Author(s)
  戸嶋一敦
- Organizer
  文部科学省科学研究費補助金新学術領域研究(研究領域提案型) 天然物ケミカルバイオロジー～分子標的と活性制御～第2回公開シンポジウム
- Place of Presentation
  東京大学
- Year and Date
  2012-06-17
- Data Source
  KAKENHI-PUBLICLY-24102528
[Presentation] インフルエンザウィルスのノイラミニダーゼを光分解するアントラキノンーシアル酸ハイブリッド分子の創製2012
- Author(s)
  青木優介、高橋大介、戸嶋一敦
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶應義塾大学
- Year and Date
  2012-03-26
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Target-selective photodegradation of glycolipid LPS and inhibition of macrophage activation by designed anthraquinone-boronic acid hybrids2012
- Author(s)
  K. Toshima
- Organizer
  8th Keio LCC - Yonsei CBMH Joint Symposium 2012
- Place of Presentation
  札幌全日空ホテル
- Year and Date
  2012-10-26
- Invited
- Data Source
  KAKENHI-PUBLICLY-24102528
[Presentation] Photodegradation of drug-resistant influenza virus neuraminidase using designed anthraquinone-sialic acid hybrids2012
- Author(s)
  K. Toshima, Y. Aoki, D. Takahashi
- Organizer
  The 12th International Kyoto Conference on New Aspects of Organic Chemistry
- Place of Presentation
  リーガロイヤルホテル京都
- Year and Date
  2012-11-12
- Data Source
  KAKENHI-PUBLICLY-24102528
[Presentation] Target-selective photo-degradation of HIV-1 protease and inhibition of HIV-1 replication in living cells by a fullerene-sugar hybrid2012
- Author(s)
  S. Tanimoto, D. Takahashi, K. Toshima
- Organizer
  26 International Carbohydrate Symposium
- Place of Presentation
  マドリード(スペイン)
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Target-selective photodegradation of glycolipid LPS and inhibition of macrophage activation by designed anthraquinone-boronic acid hybrids2012
- Author(s)
  K. Toshima
- Organizer
  8th Keio LCC - Yonsei CBMH Joint Symposium 2012
- Place of Presentation
  札幌全日空ホテル
- Invited
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] インフルエンザウィルスのノイラミニダーゼを光分解するアントラキノン-シアル酸ハイブリッド分子の創製2012
- Author(s)
  青木優介, 高橋大介, 戸嶋一敦
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶應義塾大学
- Year and Date
  2012-03-26
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] アントラセン－ケンプ酸ハイブリッドによる単糖の認識と光分解2012
- Author(s)
  西部美幸希、高橋大介、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第7回年会
- Place of Presentation
  京都大学
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] ポルフィリン誘導体によるアミロイドβの光分解2012
- Author(s)
  平林歩、高橋大介、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第7回年会
- Place of Presentation
  京都大学
- Year and Date
  2012-06-07
- Data Source
  KAKENHI-PUBLICLY-24102528
[Presentation] アントラセン－ケンプ酸ハイブリッドによる単糖の認識と光分解2012
- Author(s)
  西部美幸希、高橋大介、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第7回年会
- Place of Presentation
  京都大学
- Year and Date
  2012-06-07
- Data Source
  KAKENHI-PUBLICLY-24102528
[Presentation] Target-selective photodegradation of glycolipid LPS and inhibition of macrophage activation by designed anthraquinone-boronic acid hybrids2012
- Author(s)
  K. Toshima
- Organizer
  8th Keio LCC - Yonsei CBMH Joint Symposium 2012
- Place of Presentation
  Sapporo, Hokkaido
- Year and Date
  2012-10-26
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Photodegradation of target glycolipid LPS and inhibition of macrophage activation by anthraquinone-boronic acid hybrids2012
- Author(s)
  D. Takahashi, T. Miura, K. Toshima
- Organizer
  26 International Carbohydrate Symposium
- Place of Presentation
  Madrid, Spain
- Year and Date
  2012-07-23
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Photodegradation of glycolipid LPS and inhibition of macrophage activation using designed anthraquinoneboronic acid hybrids2012
- Author(s)
  K. Toshima
- Organizer
  17th Malaysian Chemical Congress (17MCC) 2012
- Place of Presentation
  Putra World Trade Centre, Kuala Lumpur, Malaysia
- Year and Date
  2012-10-15
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] HIV-1プロテアーゼを選択的に光分解する人工生体機能分子の創製2011
- Author(s)
  谷本周穂、高橋大介、戸嶋一敦
- Organizer
  日本化学会第91春季年会
- Place of Presentation
  神奈川大学
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] Inhibition of amyloid ・aggregation and cytotoxicity by photo-degradation using designed fullerene derivatives2011
- Author(s)
  K. Toshima
- Organizer
  The 7th Yonsei CBMH-Keio LCC Joint Symposium
- Place of Presentation
  Jeju, Korea
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Photo-degradation of proteins by fullerene derivatives2011
- Author(s)
  S.Tanimoto, Y.Ishida, D.Takahashi, K.Toshima
- Organizer
  8th AFMC International Medicinal Chemistry Symposium-Frontier of Medicinal Science-
- Place of Presentation
  京王プラザホテル
- Year and Date
  2011-12-01
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Inhibition of amyloid β aggregation and cytotoxicity by photo-degradation using designed fullerene derivatives2011
- Author(s)
  K.Toshima
- Organizer
  The 7^<th> Yonsei CBMH-Keio LCC Joint Symposium
- Place of Presentation
  チェジュ(韓国)
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Target-selective degradation of oligosaccharides by photo-activated organic molecules2011
- Author(s)
  K. Toshima
- Organizer
  14th Asian Chemical Congress
- Place of Presentation
  Bangkok, Thailand
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] 標的糖鎖を選択的に光分解する化学的手法の開発と生物学的応用2011
- Author(s)
  戸嶋一敦
- Organizer
  GlycoTOKYO 2011 シンポジウム
- Place of Presentation
  理化学研究所
- Year and Date
  2011-12-09
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Target-selective photodegradation of oligosaccharides by light-activated small molecules2011
- Author(s)
  D.Takahashi, S.Hirono, K.Toshima
- Organizer
  MDF International Workshop : Open-shell Organic Molecules-Synthesis and Electronic Structure Freedom-
- Place of Presentation
  梅田スカイビル
- Year and Date
  2011-10-07
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] 標的糖鎖を選択的に光分解する化学的手法の開発と生物学的応用2011
- Author(s)
  戸嶋一敦
- Organizer
  GlycoTOKYO 2011シンポジウム
- Place of Presentation
  理化学研究所(招待講演)
- Year and Date
  2011-12-09
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] フラーレン誘導体によるアミロイドβの光分解と神経様細胞に対する効果2011
- Author(s)
  石田泰則、藤井智彦、岡浩太郎、高橋大介、戸嶋一敦
- Organizer
  日本化学会第91春季年会
- Place of Presentation
  神奈川大学
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] アントラキノン-ボロン酸ハイブリッド分子による敗血症関連糖脂質LPSの光分解2011
- Author(s)
  三浦拓也、高橋大介、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第6回年会
- Place of Presentation
  東京工業大学
- Year and Date
  2011-05-25
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Target-selective photodegradation of oligosaccharides by light-activated small molecules2011
- Author(s)
  D. Takahashi, S. Hirono, K. Toshima
- Organizer
  MDF International Workshop : Open-shell Organic Molecules -Synthesis and Electronic Structure Freedom-
- Place of Presentation
  Umeda Sky Building, Osaka
- Year and Date
  2011-10-07
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Target-selective photodegradation of oligosaccharides by designed small organic molecules2011
- Author(s)
  K. Toshima
- Organizer
  21st International Symposium on Glycoconjugates
- Place of Presentation
  Vienna, Austria
- Year and Date
  2011-08-24
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] フラーレン-ボロン酸ハイブリッドによる標的糖鎖の選択的光分解2011
- Author(s)
  廣野信悟、高橋大介、戸嶋一敦
- Organizer
  日本化学会第91春季年会
- Place of Presentation
  神奈川大学
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] フラーレン誘導体によるHIV-1 プロテアーゼの選択的光分解とHIV-1 増殖抑制効果2011
- Author(s)
  谷本周穂, 工藤恵理子, 岡田誠治, 高橋大介, 戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第6回年会
- Place of Presentation
  東京工業大学
- Year and Date
  2011-05-23
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] 糖尿病関連タンパクα-グルコシダーゼを選択的に光分解する生体機能分子の創製2011
- Author(s)
  奥澤俊介, 青木優介, 高橋大介, 戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第6回年会
- Place of Presentation
  東京工業大学
- Year and Date
  2011-05-25
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] アントラキノン-ボロン酸ハイブリッド分子による敗血症関連糖脂質LPS の光分解2011
- Author(s)
  三浦拓也, 高橋大, 戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第6回年会
- Place of Presentation
  東京工業大学
- Year and Date
  2011-05-25
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Development of an innovative method for target-selective photodegradation of oligosaccharides by light-activated small molecules2011
- Author(s)
  D. Takahashi, S. Hirono, C. Hayashi, M. Igarashi, Y. Nishimura, K. Toshima
- Organizer
  The 31th Naito Conference on Glycan Expression and Regulation [II]
- Place of Presentation
  Chateraise Gateaux Kingdom Sapporo, Hokkaido, Japan
- Year and Date
  2011-09-14
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] アントラキノン-レクチンハイブリッドの創製と標的糖鎖選択的光分解2011
- Author(s)
  今井ゆかり、廣野信悟、松葉悠、小林夕香、河岸洋和、高橋大介、戸嶋一敦
- Organizer
  日本化学会第91春季年会
- Place of Presentation
  神奈川大学
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] フラーレン誘導体によるHIV-1プロテアーゼの選択的光分解とHIV-1増殖抑制効果2011
- Author(s)
  谷本周穂、工藤恵理子、岡田誠治、高橋大介、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第6回年会
- Place of Presentation
  東京工業大学
- Year and Date
  2011-05-23
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Target-selective photodegradation of oligosaccharides by designed small organic molecules2011
- Author(s)
  K.Toshima
- Organizer
  21^<st> International Symposium on Glycoocnjugates
- Place of Presentation
  ウィーン(オーストリア)(招待講演)
- Year and Date
  2011-08-24
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Target-selective degradation of oligosaccharides by photo-activated organic molecules2011
- Author(s)
  K.Toshima
- Organizer
  14^<th> Asian Chemical Congress
- Place of Presentation
  バンコク(タイ)(招待講演)
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Photo-degradation of proteins by fullerene derivatives2011
- Author(s)
  S. Tanimoto, Y. Ishida, D. Takahashi, K. Toshima
- Organizer
  8th AFMC International Medicinal Chemistry Symposium-Frontier of Medicinal Science
- Place of Presentation
  Keio Plaza Hotel, Tokyo, Japan
- Year and Date
  2011-12-01
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] Development of an innovative method for target-selective photodegradation of oligosaccharides by light-activated small molecules2011
- Author(s)
  D.Takahashi, S.Hirono, C.Hayashi, M.Igarashi, Y.Nishimura, K.Toshima
- Organizer
  The 31th Naito Conference on Glycan Expression and Regulation [II]
- Place of Presentation
  ガトーキングダムサッポロ
- Year and Date
  2011-09-14
- Data Source
  KAKENHI-PROJECT-23310153
[Presentation] エストロゲンレセプターαを選択的に光分解する小分子の創製と乳がん細胞の増殖抑制2010
- Author(s)
  津村加奈、梅澤一夫、高橋大介、戸嶋一敦
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  近畿大学
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] 結核菌の構成糖鎖を選択的に光分解する光感受性入工生体機能分子の創製2010
- Author(s)
  高橋大介、廣野信吾、林千草、五十嵐雅之、西村吉雄、戸嶋一敦
- Organizer
  GlycoTOKYO 2010 シンポジウム
- Place of Presentation
  東京大学薬学部
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] フラーレン-糖ハイブリッド分子によるアミロイドβの光分解2010
- Author(s)
  石田泰則、高橋大介、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第5回年会
- Place of Presentation
  慶應義塾大学日吉キャンパス
- Year and Date
  2010-05-18
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] エストロゲンレセプターαを選択的に光分解する小分子の創製と乳がん細胞の増殖抑制2010
- Author(s)
  津村加奈, 梅澤一夫, 高橋大介, 戸嶋一敦
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  近畿大学(大阪)
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] 標的糖鎖を選択的に分解する生体機能分子の有機合成化学的創製-アントラキノン-ボロン酸ハイブリッドによる結核菌糖鎖の光分解2010
- Author(s)
  高橋大介、廣野信吾、戸嶋一敦
- Organizer
  第97回有機合成シンポジウム
- Place of Presentation
  慶應義塾大学薬学部芝共立キャンパス
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] Synthetic and chemical biological studies in Toshima's group at Keio University, Workshop on Organic Chemistry and Synthetic Biology2010
- Author(s)
  K.Toshima
- Organizer
  Japan-Netherlands Joint Symposium on Organic Chemistry and Chemical Biology
- Place of Presentation
  オランダ日本大使館(東京)
- Year and Date
  2010-10-04
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] Target-selective photodegradation of oligosaccharides by light-activated small molecules2010
- Author(s)
  D.Takahashi, S.Hirono, C.Hayashi, M.Igarashi, Y.Nishimura, K.Toshima
- Organizer
  25th International Carbohydrate Symposium
- Place of Presentation
  Tokyo, Makuhari
- Year and Date
  2010-08-02
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] Development of HIV-1 protease-selective photo-degrading molecules2010
- Author(s)
  S.Tanimoto, S.Sakai, Y.Ishida, D.Takahashi, K.Toshima
- Organizer
  2010 International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  ホノルル(アメリカ)
- Year and Date
  2010-12-19
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] アントラキノン-ボロン酸ハイブリッドによる標的糖鎖の選択的光分解と抗結核菌作用2010
- Author(s)
  廣野信吾、林千草、五十嵐雅之、西村吉雄、高橋大介、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第5回年会
- Place of Presentation
  慶應義塾大学日吉キャンパス
- Year and Date
  2010-05-18
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] アントラキノン-ボロン酸ハイブリッド分子による標的糖鎖の選択的光分解2010
- Author(s)
  廣野信吾、高橋大介、戸嶋一敦
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  近畿大学
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] Synthetic and chemical biological studies in Toshima's group at Keio University2010
- Author(s)
  戸嶋一敦
- Organizer
  Workshop on Organic Chemistry and Synthetic Biology, Japan-Netherlands
- Place of Presentation
  Netherlands Embassy Tokyo
- Year and Date
  2010-10-04
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] Development of HIV-1 protease-selective photo-degrading molecules2010
- Author(s)
  S.Tanimoto, S.Sakai, Y.Ishida, D.Takahashi, K.Toshima
- Organizer
  2010 International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu, Hawaii
- Year and Date
  2010-12-19
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] Target-selective photodegradation of oligosaccharides by light-activated anthraquinone-boronic acid hybrid2010
- Author(s)
  K.Toshima, S.Hirono, D.Takahashi
- Organizer
  6^<th> Keio LCC-Yonsei CBMH Joint Symposium
- Place of Presentation
  Kinugawa
- Year and Date
  2010-10-22
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] Target-selective photo-degradation of oligosaccharides by designed organic molecules2010
- Author(s)
  戸嶋一敦
- Organizer
  2010 International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu, Hawaii
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] HIV-1プロテアーゼを選択的に光分解するフラーレンー糖ハイブリッド分子の有機合成化学的創製2010
- Author(s)
  谷本周穂、酒井聡史、石田泰則、高橋大介、戸嶋一敦
- Organizer
  第59回有機合成化学協会関東支部シンポジウム
- Place of Presentation
  東京農工大小金井キャンパス
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] アントラキノンーボロン酸ハイブリッド分子による標的糖鎖の選択的光分解2010
- Author(s)
  廣野信吾, 高橋大介, 戸嶋一敦
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  近畿大学(大阪)
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] 標的糖鎖を選択的に分解する生体機能分子の有機合成化学的創製-アントラキノンーボロン酸ハイブリッドによる結核菌糖鎖の光分解2010
- Author(s)
  高橋大介、廣野信吾、戸嶋一敦
- Organizer
  第97回有機合成シンポジウム
- Place of Presentation
  慶應義塾大学薬学部芝共立キャンパス
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] Target-selective photodegradation of oligosaccharides by designed organic molecules2010
- Author(s)
  K.Toshima
- Organizer
  2010 International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  ホノルル(アメリカ)
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] 標的糖鎖を光分解する生体機能分子の創製、理研シンポジウム2010
- Author(s)
  戸嶋一敦
- Organizer
  第13回「生体分子の化学」
- Place of Presentation
  理化学研究所
- Year and Date
  2010-01-29
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] 結核菌の構成糖鎖を選択的に光分解する光感受性人工生体機能分子の創製2010
- Author(s)
  高橋大介、廣野信吾、林千草、五十嵐雅之、西村吉雄、戸嶋一敦
- Organizer
  GlycoTOKYO 2010シンポジウム
- Place of Presentation
  東京大学薬学部
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] Target-selective photodegradation of oligosaccharides by light-activated small molecules2010
- Author(s)
  D.Takahashi, S.Hirono, C.Hayashi, M.Igarashi, Y.Nishimura, K.Toshima
- Organizer
  25^<th> International Carbohydrate Symposium
- Place of Presentation
  幕張メッセ国際会議場
- Year and Date
  2010-08-02
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] フラーレン-糖ハイブリッド分子によるアミロイドβの光分解2010
- Author(s)
  石田泰則, 高橋大介, 戸嶋一敦
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  近畿大学(大阪)
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] HIV-1プロテアーゼを選択的に光分解するフラーレン-糖ハイブリッド分子の有機合成化学的創製2010
- Author(s)
  谷本周穂、酒井聡史、石田泰則、高橋大介、戸嶋一敦
- Organizer
  第59回有機合成化学協会関東支部シンポジウム
- Place of Presentation
  東京農工大小金井キャンパス
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] フラーレン-糖ハイブリッド分子によるアミロイドβの光分解2010
- Author(s)
  石田泰則、高橋大介、戸嶋一敦
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  近畿大学
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] Target-selective photo-degradation of HIV1-protease by fullerene derivatives2009
- Author(s)
  高橋大介, 谷本周穂, 酒井聡史, 戸嶋一敦
- Organizer
  The 25^<th> Naito Conference on Chemical Biology [II]
- Place of Presentation
  シャトレーゼガトーキングダムサッポロ(札幌)
- Year and Date
  2009-09-09
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] 疾患関連タンパクを選択的に光分解する生体機能分子の創製と応用2009
- Author(s)
  戸嶋一敦
- Organizer
  第3回慶應義塾大学理工学部ハイテクリサーチセンターシンポジウム-機能性分子その医療への応用-
- Place of Presentation
  横浜情報文化センター
- Year and Date
  2009-07-14
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] フラーレン-誘導体によるHIV-1プロテアーゼ選択的光分解2009
- Author(s)
  谷本周穂、酒井聡史、石田泰則、高橋大介、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第4回年会
- Place of Presentation
  神戸
- Year and Date
  2009-05-18
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] ポルフィリン誘導体によるエストロゲン受容体タンパクの選択的光分解2009
- Author(s)
  谷本周穂、松村秀一、戸嶋一敦
- Organizer
  日本化学会第89春季年会
- Place of Presentation
  日本大学
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] フラーレン-誘導体によるHIV-1プロテアーゼ選択的光分解2009
- Author(s)
  谷本周穂, 酒井聡史, 石田泰則, 高橋大介, 戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第4回年会
- Place of Presentation
  神戸市産業振興センター(神戸)
- Year and Date
  2009-05-18
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] フラーレン-糖ハイブリツドによるHIV-1プロテアーゼの選択的光分解2009
- Author(s)
  高橋大介, 酒井聡史, 谷本周穂, 戸嶋一敦
- Organizer
  日本化学会第89春季年会
- Place of Presentation
  日本大学
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation]2009
- Author(s)
  D.Takahashi, S.Tanimoto, S.Sakai, K.Toshima
- Organizer
  The 25^<th> Naito Conference on Chemical Biology [II]
- Place of Presentation
  Sapporo
- Year and Date
  2009-09-09
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] 疾患関連タンパクを選択的に光分解する生体機能分子の創製と応用2009
- Author(s)
  戸嶋一敦
- Organizer
  第3回慶應義塾大学理工学部ハイテクリサーチセンターシンポジウム―機能性分子その疾療への応用―
- Place of Presentation
  横浜情報文化センター(横浜)
- Year and Date
  2009-07-14
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] フラーレン-糖ハイブリッドによるHIV-1プロテアーゼの選択的光分解2009
- Author(s)
  高橋大介、酒井聡史、谷本周穂、戸嶋一敦
- Organizer
  日本化学会第89春季年会
- Place of Presentation
  日本大学
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] Target-selective degradation of proteins by designed and light-activated small molecules2008
- Author(s)
  K. Toshima
- Organizer
  2008 RIKEN Conference on Chemical Biology
- Place of Presentation
  ラディソンホテル成田
- Year and Date
  2008-11-13
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] Target-selective degradation of oligosaccharides by a light-activated small molecule-lection hybrid2008
- Author(s)
  戸嶋一敦
- Organizer
  The 4th Keio LCC-Yonsei CBMH Joint Symposium
- Place of Presentation
  Keio University
- Year and Date
  2008-09-16
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] 2-フェニルキノリン-ステロイドホルモンハイブリツド分子による標的タンパク選択的光分解と抗細胞活性2008
- Author(s)
  津村加奈, 鈴木あかね, 続木武男, 松村秀一, 梅渾一夫, 戸嶋一敦
- Organizer
  日本ケミカルバイオロジー研究会第3回年会
- Place of Presentation
  学術総合センター(東京)
- Year and Date
  2008-05-19
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] Target-selective degradation of proteins by designed and light-activated small molecules2008
- Author(s)
  戸嶋一敦
- Organizer
  2008 RIKEN Conference on Chemical Biology
- Place of Presentation
  Narita
- Year and Date
  2008-11-13
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] フラーレン誘導体による標的タンパク選択的光分解2008
- Author(s)
  酒井聡史、谷本周穂、松村秀一、戸嶋一敦
- Organizer
  第12回がん分子標的治療研究会総会
- Place of Presentation
  学術総合センター(東京)
- Year and Date
  2008-06-27
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] 2-フェニルキノリン-エストラジオールハイブリッド人工分子による細胞内標的タンパク光分解と細胞増殖抑制2008
- Author(s)
  津村加奈, 続木武男, 松村秀一, 梅澤一夫, 戸嶋一敦
- Organizer
  第3回バイオ関連化学合同シンポジウム
- Place of Presentation
  東京工業大学
- Year and Date
  2008-09-18
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] ポルフィリン誘導体によるエストロゲン受容体タンパク選択的光分解2008
- Author(s)
  谷本周穂、松村秀一、戸嶋一敦
- Organizer
  第3回バイオ関連化学合同シンポジウム
- Place of Presentation
  東京工業大学
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] 標的タンパクを選択的に光分解する光感受性分子の創製と応用2008
- Author(s)
  戸嶋一敦
- Organizer
  第12回がん分子標的治療研究会総会
- Place of Presentation
  学術総合センター(東京)
- Year and Date
  2008-06-26
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] Target-selective degradation of oligosaccharides by a light-activated small anthraquinone-lection hybrid2008
- Author(s)
  K. Toshima
- Organizer
  24^<th> International Carbohydrate Symposium
- Place of Presentation
  オスロ(ノルウェー)
- Year and Date
  2008-07-29
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] Target-selective degradation of oligosaccharides by a light-activated small anthraquinone-lection hybrid2008
- Author(s)
  戸嶋一敦
- Organizer
  24th International Carbohydrate Symposium
- Place of Presentation
  Oslo
- Year and Date
  2008-07-29
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] フラーレン-糖鎖ハイブリッド分子によるHIV-1 プロテアーゼ選択的光分解2008
- Author(s)
  酒井聡史, 谷本周穂, 松村秀一, 高橋大介, 戸嶋一敦
- Organizer
  第3回バイオ関連化学合同シンポジウム
- Place of Presentation
  東京工業大学
- Year and Date
  2008-09-18
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] Target-selective degradation of oligosaccharides by a light-activated small molecule-lection hybrid2008
- Author(s)
  K. Toshima
- Organizer
  The 4^<th> Keio LCC-Yonsei CBMH Joint Symposium
- Place of Presentation
  慶應義塾大学理工学部
- Year and Date
  2008-09-16
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] 2-フェニルキノリン-ステロイドホルモンハイブリッド分子による標的タンパク選択的光分解と抗細胞活性2008
- Author(s)
  津村加奈、鈴木あかね、続木武男、松村秀一、梅澤一夫、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー研究会第3回年会
- Place of Presentation
  学術総合センター(東京)
- Year and Date
  2008-05-19
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] ポルフィリン系化合物による標的タンパク選択的光分解2008
- Author(s)
  谷本周穂、松村秀一、戸嶋一敦
- Organizer
  第12回がん分子標的治療研究会総会
- Place of Presentation
  学術総合センター(東京)
- Year and Date
  2008-06-27
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] フラーレンー糖鎖ハイブリッド分子によるHIV-1プロテアーゼ選択的光分解2008
- Author(s)
  酒井聡史、谷本周穂、松村秀一、高橋大介、戸嶋一敦
- Organizer
  第3回バイオ関連化学合同シンポジウム
- Place of Presentation
  東京工業大学
- Year and Date
  2008-09-18
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] 2-フェニルキノリンーエストラジオールハイブリッド人工分子による細胞内標的タンパク光分解と細胞増殖抑制2008
- Author(s)
  津村加奈、続木武男、松村秀一、梅澤一夫、戸嶋一敦
- Organizer
  第3回バイオ関連化学合同シンポジウム
- Place of Presentation
  東京工業大学
- Year and Date
  2008-09-18
- Data Source
  KAKENHI-PROJECT-20310140
[Presentation] Chemical glycosylation methods inspired by new biomimetic concepts and their application to antural products synthesis2007
- Author(s)
  K. Toshima
- Organizer
  The 234th ACS National Meeting
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-18032068
[Presentation] 糖質および抗生物質の合成と生体機能光制御分子の創製に関する研究
- Author(s)
  戸嶋一敦
- Organizer
  日本化学会第95春季年会
- Place of Presentation
  日本大学(千葉県船橋市）
- Year and Date
  2015-03-26 – 2015-03-29
- Invited
- Data Source
  KAKENHI-PROJECT-26282212
[Presentation] 標的生体高分子を選択的に光分解する化学的手法の開発と生物学的応用
- Author(s)
  戸嶋一敦
- Organizer
  国際高等研究所研究プロジェクト「分子基盤に基づく生体機能への揺らぎとダイナミックネットワークの解明」2014年度第1回研究プログラム
- Place of Presentation
  国際高等研究所(京都府木津川市）
- Year and Date
  2014-12-14 – 2014-12-15
- Invited
- Data Source
  KAKENHI-PUBLICLY-26102738
[Presentation] 糖アクロシドのマイケルアクセプターとしての化学及び生物学的機能
- Author(s)
  池田裕政、金子英利香、奥澤俊介、高橋大介、戸嶋一敦
- Organizer
  第33回日本糖質学会年会
- Place of Presentation
  名古屋大学(名古屋市千種区）
- Year and Date
  2014-08-10 – 2014-08-12
- Data Source
  KAKENHI-PUBLICLY-26102738
[Presentation] Total synthesis of vineomycin B2 : Application of glycosylation method using 2,3-unsaturated sugars to natural products synthesis
- Author(s)
  K. Toshima
- Organizer
  Vietnam Malaysia International Chemical Congress (VMICC2014)
- Place of Presentation
  ハノイ(ベトナム）
- Year and Date
  2014-11-07 – 2014-11-09
- Invited
- Data Source
  KAKENHI-PUBLICLY-26102738
[Presentation] アントラキノン-ハルミンハイブリッドによるアルツハイマー病関連タンパクDYRK1Aの選択的光分解
- Author(s)
  奥山真衣、増田奏衣、高橋大介、戸嶋一敦
- Organizer
  日本化学会第95春季年会
- Place of Presentation
  日本大学(千葉県船橋市）
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PUBLICLY-26102738
[Presentation] ノロウイルス関連タンパクVP1を光分解するアントラキノン‐H抗原糖鎖ハイブリッドの創製
- Author(s)
  志村拓海、大久保聡太、上野晴菜、高橋大介、戸嶋一敦
- Organizer
  日本化学会第95春季年会
- Place of Presentation
  日本大学(千葉県船橋市）
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PUBLICLY-26102738
[Presentation] ノロウイルス関連タンパクVP1を光分解するアントラキノン‐H抗原糖鎖ハイブリッドの創製
- Author(s)
  志村拓海、大久保聡太、上野晴菜、高橋大介、戸嶋一敦
- Organizer
  日本化学会第95春季年会
- Place of Presentation
  日本大学(千葉県船橋市）
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-26282212
[Presentation] アントラキノン－抗体ハイブリッドの創製とシアリルルイスA糖鎖選択的光分解
- Author(s)
  戸嶋一敦
- Organizer
  新学術領域研究(研究領域提案型)天然物ケミカルバイオロジー～分子標的と活性制御～第6回シンポジウム
- Place of Presentation
  名古屋大学(名古屋市千種区）
- Year and Date
  2014-05-28 – 2014-05-29
- Data Source
  KAKENHI-PUBLICLY-26102738
[Presentation] 糖質および抗生物質の合成と生体機能光制御分子の創製に関する研究
- Author(s)
  戸嶋一敦
- Organizer
  日本化学会第95春季年会
- Place of Presentation
  日本大学(千葉県船橋市）
- Year and Date
  2015-03-26 – 2015-03-29
- Invited
- Data Source
  KAKENHI-PUBLICLY-26102738
[Presentation] Total synthesis of vineomycin B2 : Application of glycosylation method using 2,3-unsaturated sugars to natural products synthesis
- Author(s)
  K. Toshima
- Organizer
  Vietnam Malaysia International Chemical Congress (VMICC2014)
- Place of Presentation
  ハノイ(ベトナム）
- Year and Date
  2014-11-07 – 2014-11-09
- Invited
- Data Source
  KAKENHI-PROJECT-26282212
[Presentation] アントラキノン-ハルミンハイブリッドによるアルツハイマー病関連タンパクDYRK1Aの選択的光分解
- Author(s)
  奥山真衣、増田奏衣、高橋大介、戸嶋一敦
- Organizer
  日本化学会第95春季年会
- Place of Presentation
  日本大学(千葉県船橋市）
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-26282212
[Presentation] アントラキノン－抗体ハイブリッドによるシアリルルイスA糖鎖の選択的光分解
- Author(s)
  長尾高志、高橋大介、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第9回年会
- Place of Presentation
  大阪大学(大阪府豊中市）
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PUBLICLY-26102738
[Presentation] Taeget-selective photodegradation of proteins and oligosaccharides
- Author(s)
  K. Toshima
- Organizer
  The 3rd International Symposium on Chemical Biology of Natural products : Target ID and Regulation of Bioactivity
- Place of Presentation
  千里ライフサイエンスセンター(大阪府豊中市）
- Year and Date
  2014-10-28 – 2014-10-29
- Data Source
  KAKENHI-PUBLICLY-26102738
[Presentation] 標的生体高分子を選択的に光分解する化学的手法の開発と生物学的応用
- Author(s)
  戸嶋一敦
- Organizer
  国際高等研究所研究プロジェクト「分子基盤に基づく生体機能への揺らぎとダイナミックネットワークの解明」2014年度第1回研究プログラム
- Place of Presentation
  国際高等研究所(京都府木津川市）
- Year and Date
  2014-12-14 – 2014-12-15
- Invited
- Data Source
  KAKENHI-PROJECT-26282212
[Presentation] アントラキノン－抗体ハイブリッドによるシアリルルイスA糖鎖の選択的光分解
- Author(s)
  長尾高志、高橋大介、戸嶋一敦
- Organizer
  日本ケミカルバイオロジー学会第9回年会
- Place of Presentation
  大阪大学(大阪府豊中市）
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-26282212

1. MATSUMURA Shuichi (30051874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
2. 竹本佳司 (20227060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 秋山隆彦 (60202553)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 石原一彰 (40221759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 川端猛夫 (50214680)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 笹井宏明 (90205831)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TAKAHASHI Daisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
8. 谷本周穂

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
9. 今井宏明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 緒明佑哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TOSHIMA Kazunobu 戸嶋 一敦

戸嶋 一敦 トシマ カズノブ

Research Projects

Research Products

Co-Researchers

天然物を基本骨格とする刺激応答型光感受性分子の創製と次世代型光線力学療法への応用Principal Investigator

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機能複合化による生体機能光制御中分子の創製Principal Investigator

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生体機能光制御分子の創製とケミカルバイオロジーへの応用Principal Investigator

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Creation of agents that selectively photo-degrade certain proteins and oligosaccharides and its application to control of cell functionsPrincipal Investigator

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生体機能光制御分子の創製とケミカルバイオロジーへの応用Principal Investigator

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Creation of Novel Biofunctional Molecules for Target-Selective Photodegradation of Proteins and CarbohydratesPrincipal Investigator

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Development of designed agents that selectively photo-degrade certain proteins and oligosaccharidesPrincipal Investigator

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糖を有する生体機能分子のための新合成方法論と実践的合成法の開発Principal Investigator

Principal Investigator

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酸・塩基複合型有機触媒の精密設計

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Novel Sustainable chemical recycling of green polymers using environmentally benign catalytic process

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THE DEVELOPMENT OF ARTIFICIAL GENE REGULATION MOLECULES BASED ON CHEMICAL BIOLOGYPrincipal Investigator

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Molecular Design and Evaluation of Artificial Gene Function-Regulating Agents in the Post-Genome EraPrincipal Investigator

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人工設計分子とDNAの超分子形成に基いた遺伝子機能制御Principal Investigator

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TOSHIMA Kazunobu 戸嶋一敦

戸嶋一敦トシマカズノブ

[Book] 有機分子触媒の新展開(柴崎正勝監修)2006