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TOYAMA Akira  外山 聡

ORCIDConnect your ORCID iD *help
Researcher Number 60217560
Other IDs
Affiliation (Current) 2022: 新潟大学, 医歯学総合病院, 教授
Affiliation (based on the past Project Information) *help 2005 – 2006: 新潟大学, 医歯学総合病院, 助教授
1999 – 2004: 東北大学, 大学院・薬学研究科, 助手
1995 – 1996: 東北大学, 薬学部, 助手
1991: Tohoku Univ., Pharm. Inst., Assistant, 薬学部, 助手
1989 – 1990: 東北大学, 薬学部, 教務職員
Review Section/Research Field
Principal Investigator
Physical pharmacy / Physical chemistry / Physical pharmacy
Except Principal Investigator
構造化学 / Physical chemistry / Physical chemistry
Keywords
Principal Investigator
紫外共鳴ラマン分光 / DNA-薬物相互作用 / 選択的重水素化DNA / 共鳴ラマン分光 / 核酸構造 / 核酸-薬物相互作用 / アデニンヌクレオチド / 蛋白-核酸相互作用 / 紫外共鳴ラマン分光法 / 選択的重水素ラベル … More / アデニン残基 / アクチノマイシンD / 共鳴ラマン分光法 / 重水素ラベルDNA / site-selective deuterated DNA / resonance Raman spectroscopy / nucleic acid structure / nucleic acid-drug interaction / 薬物-核酸相互作用 / UV resonance Raman spectroscopy / Drug-nucleic acid interaction / Site-selective deuterated DNA / Nucleic acid structure … More
Except Principal Investigator
紫外共鳴ラマン分光 / CCD / タンパク質 / Protein / ラマン分光法 / 前置プリズム分光器 / 紫外分光器 / 迷光 / マルチチャンネルディテクタ- / 紫外共鳴ラマン / CCD検出器 / 紫外ラマン分光装置 / UVRR spectroscopy / Raman spectroscopy / Fore-prism spectrometer / UV spectrometer / Stray light / Multichannel detector / Proteins / 顕微鏡 / 蛋白質 / 核酸 / 細胞構造 / Microscope / Nucleic acid / Cell structure / UV resonance Raman spectroscopy / カチオン-π相互作用 / ニューロメディン / 蛍光スペクトル / 紫外共鳴ラマンスペクトル / インフルエンザ / ウイルス / イオンチャネル / 構造 / 円偏光二色性 / 紫外共鳴ラマン分光法 / Cation-π interaction / Neuromedin / Fluorescence Spectra / UV Resonance Raman Spectra / Influenza / Virus / Ion Channel / 調節蛋白 / 蛋白一核酸相互作用 / スペクトルー構造相関 / 蛋白ー核酸相互作用 / DNA / Ultraviolet Resonance Raman Rpectroscopy / Regulatory Protein / Protein Nucleic Acid Interactions / Spectrum-Structure Relation Less
  • Research Projects

    (8 results)
  • Research Products

    (5 results)
  • Co-Researchers

    (9 People)
  •  Dynamic control of protein structure by cation-π interaction

    • Principal Investigator
      TAKEUCHI Hideo
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Physical chemistry
    • Research Institution
      Tohoku University
  •  Detection of DNA structural changes upon drug-binging by a combination of site-selective deutaretation and difference Raman intensity changesPrincipal Investigator

    • Principal Investigator
      TOYAMA Akira
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Tohoku University
  •  Detection of small structural changes of DNA under physiological conditions by a combination of site-selective deuteration and Raman difference spectroscopyPrincipal Investigator

    • Principal Investigator
      TOYAMA Akira
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Tohoku University
  •  重水素置換と共鳴ラマン分光法を併用した薬物-DNAオリゴマ-相互作用の構造研究Principal Investigator

    • Principal Investigator
      外山 聡
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Physical pharmacy
    • Research Institution
      Tohoku University
  •  紫外共鳴ラマン分光法による蛋白質に結合したアデニンヌクレオチドの構造研究Principal Investigator

    • Principal Investigator
      外山 聡
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Physical chemistry
    • Research Institution
      Tohoku University
  •  Development of an Ultraviolet Raman Microspectrometer Applicable to Structural Analyzes of Cells

    • Principal Investigator
      TAKEUCHI Hideo
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Physical chemistry
    • Research Institution
      Tohoku University
  •  A High-Pereormance Ultraviolet Apparatus

    • Principal Investigator
      HARADA Issei
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      構造化学
    • Research Institution
      Tohoku University
  •  Ultraviolet Resonance Raman Spectroscopic Study on Regulatory Protein-Nucleic Acid Interactions

    • Principal Investigator
      HARADA Issei
    • Project Period (FY)
      1987 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      構造化学
    • Research Institution
      Tohoku University

All 2005 Other

All Journal Article

  • [Journal Article] Correlation between UV Raman intensity and hydrogen bonding of the adenine ring2005

    • Author(s)
      Akira Toyama
    • Journal Title

      Journal of Molecular Structure 735-763

      Pages: 235-241

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590036
  • [Journal Article] Correlation between UV Raman Intensity and Hydrogen Bonding of the Adenine Ring2005

    • Author(s)
      Akira Toyama
    • Journal Title

      Journal of Molecular Structure 235-236・1

      Pages: 235-241

    • Data Source
      KAKENHI-PROJECT-15590036
  • [Journal Article] Isotope-edited UV Raman spectroscopy of protein-DNA interactions : Binding modes of cyclic AMP receptor protein to a natural DNA recognition site2005

    • Author(s)
      Akira Toyama
    • Journal Title

      Journal of Raman Spectroscopy 36

      Pages: 300-306

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590036
  • [Journal Article] Correlation between UV Raman intensity and hydrogen bonding of the adenine ring2005

    • Author(s)
      Akira Toyama
    • Journal Title

      Journal of Molecular Structure 735-736

      Pages: 235-241

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590036
  • [Journal Article] Isotope-edited UV Raman spectroscopy of protein-DNA interactions : Binding modes of cyclic AMP receptor protein to a natural DNA recognition site

    • Author(s)
      Akira Toyama
    • Journal Title

      Journal of Raman Spectroscopy (印刷中)

    • Data Source
      KAKENHI-PROJECT-15590036
  • 1.  HASHIMOTO Shinji (50192696)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  TAKEUCHI Hideo (30111454)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  HARADA Issei (70011583)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  MIURA Takashi (30222318)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  UCHIDA Kiyoshi (70129352)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  廣谷 恵理 (10192303)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  古川 行夫 (50156965)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  IKEDA Takeshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  小林 隆男
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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