TOYAMA Akira 外山聡

Researcher Number	60217560
Other IDs
Affiliation (Current)	2022: 新潟大学, 医歯学総合病院, 教授
Affiliation (based on the past Project Information) *help	2005 – 2006: 新潟大学, 医歯学総合病院, 助教授 1999 – 2004: 東北大学, 大学院・薬学研究科, 助手 1995 – 1996: 東北大学, 薬学部, 助手 1991: Tohoku Univ., Pharm. Inst., Assistant, 薬学部, 助手 1989 – 1990: 東北大学, 薬学部, 教務職員
Review Section/Research Field	Principal Investigator Physical pharmacy / Physical chemistry / Physical pharmacy Except Principal Investigator 構造化学 / Physical chemistry / Physical chemistry
Keywords	Principal Investigator 紫外共鳴ラマン分光 / DNA-薬物相互作用 / 選択的重水素化DNA / 共鳴ラマン分光 / 核酸構造 / 核酸-薬物相互作用 / アデニンヌクレオチド / 蛋白-核酸相互作用 / 紫外共鳴ラマン分光法 / 選択的重水素ラベル … More / アデニン残基 / アクチノマイシンD / 共鳴ラマン分光法 / 重水素ラベルDNA / site-selective deuterated DNA / resonance Raman spectroscopy / nucleic acid structure / nucleic acid-drug interaction / 薬物-核酸相互作用 / UV resonance Raman spectroscopy / Drug-nucleic acid interaction / Site-selective deuterated DNA / Nucleic acid structure … More Except Principal Investigator 紫外共鳴ラマン分光 / CCD / タンパク質 / Protein / ラマン分光法 / 前置プリズム分光器 / 紫外分光器 / 迷光 / マルチチャンネルディテクタ- / 紫外共鳴ラマン / CCD検出器 / 紫外ラマン分光装置 / UVRR spectroscopy / Raman spectroscopy / Fore-prism spectrometer / UV spectrometer / Stray light / Multichannel detector / Proteins / 顕微鏡 / 蛋白質 / 核酸 / 細胞構造 / Microscope / Nucleic acid / Cell structure / UV resonance Raman spectroscopy / カチオン-π相互作用 / ニューロメディン / 蛍光スペクトル / 紫外共鳴ラマンスペクトル / インフルエンザ / ウイルス / イオンチャネル / 構造 / 円偏光二色性 / 紫外共鳴ラマン分光法 / Cation-π interaction / Neuromedin / Fluorescence Spectra / UV Resonance Raman Spectra / Influenza / Virus / Ion Channel / 調節蛋白 / 蛋白一核酸相互作用 / スペクトルー構造相関 / 蛋白ー核酸相互作用 / DNA / Ultraviolet Resonance Raman Rpectroscopy / Regulatory Protein / Protein Nucleic Acid Interactions / Spectrum-Structure Relation Less

Dynamic control of protein structure by cation-π interaction
- Principal Investigator
  
  TAKEUCHI Hideo
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical chemistry
- Research Institution
  Tohoku University
Detection of DNA structural changes upon drug-binging by a combination of site-selective deutaretation and difference Raman intensity changesPrincipal Investigator
- Principal Investigator
  
  TOYAMA Akira
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Tohoku University
Detection of small structural changes of DNA under physiological conditions by a combination of site-selective deuteration and Raman difference spectroscopyPrincipal Investigator
- Principal Investigator
  
  TOYAMA Akira
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Tohoku University
重水素置換と共鳴ラマン分光法を併用した薬物-DNAオリゴマ-相互作用の構造研究Principal Investigator
- Principal Investigator
  
  外山聡
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  Tohoku University
紫外共鳴ラマン分光法による蛋白質に結合したアデニンヌクレオチドの構造研究Principal Investigator
- Principal Investigator
  
  外山聡
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Physical chemistry
- Research Institution
  Tohoku University
Development of an Ultraviolet Raman Microspectrometer Applicable to Structural Analyzes of Cells
- Principal Investigator
  
  TAKEUCHI Hideo
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Physical chemistry
- Research Institution
  Tohoku University
A High-Pereormance Ultraviolet Apparatus
- Principal Investigator
  
  HARADA Issei
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  構造化学
- Research Institution
  Tohoku University
Ultraviolet Resonance Raman Spectroscopic Study on Regulatory Protein-Nucleic Acid Interactions
- Principal Investigator
  
  HARADA Issei
- Project Period (FY)
  1987 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  構造化学
- Research Institution
  Tohoku University

All 2005 Other

All Journal Article

[Journal Article] Correlation between UV Raman intensity and hydrogen bonding of the adenine ring2005
- Author(s)
  Akira Toyama
- Journal Title
  
  Journal of Molecular Structure 735-763
  
  Pages: 235-241
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590036
[Journal Article] Correlation between UV Raman Intensity and Hydrogen Bonding of the Adenine Ring2005
- Author(s)
  Akira Toyama
- Journal Title
  
  Journal of Molecular Structure 235-236・1
  
  Pages: 235-241
- Data Source
  KAKENHI-PROJECT-15590036
[Journal Article] Isotope-edited UV Raman spectroscopy of protein-DNA interactions : Binding modes of cyclic AMP receptor protein to a natural DNA recognition site2005
- Author(s)
  Akira Toyama
- Journal Title
  
  Journal of Raman Spectroscopy 36
  
  Pages: 300-306
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590036
[Journal Article] Correlation between UV Raman intensity and hydrogen bonding of the adenine ring2005
- Author(s)
  Akira Toyama
- Journal Title
  
  Journal of Molecular Structure 735-736
  
  Pages: 235-241
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590036
[Journal Article] Isotope-edited UV Raman spectroscopy of protein-DNA interactions : Binding modes of cyclic AMP receptor protein to a natural DNA recognition site
- Author(s)
  Akira Toyama
- Journal Title
  
  Journal of Raman Spectroscopy (印刷中)
- Data Source
  KAKENHI-PROJECT-15590036

1. HASHIMOTO Shinji (50192696)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. TAKEUCHI Hideo (30111454)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. HARADA Issei (70011583)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. MIURA Takashi (30222318)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. UCHIDA Kiyoshi (70129352)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 廣谷恵理 (10192303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 古川行夫 (50156965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. IKEDA Takeshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 小林隆男

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TOYAMA Akira 外山 聡

Research Projects

Research Products

Co-Researchers

Dynamic control of protein structure by cation-π interaction

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Detection of DNA structural changes upon drug-binging by a combination of site-selective deutaretation and difference Raman intensity changesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Detection of small structural changes of DNA under physiological conditions by a combination of site-selective deuteration and Raman difference spectroscopyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

重水素置換と共鳴ラマン分光法を併用した薬物-DNAオリゴマ-相互作用の構造研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

紫外共鳴ラマン分光法による蛋白質に結合したアデニンヌクレオチドの構造研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of an Ultraviolet Raman Microspectrometer Applicable to Structural Analyzes of Cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A High-Pereormance Ultraviolet Apparatus

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Ultraviolet Resonance Raman Spectroscopic Study on Regulatory Protein-Nucleic Acid Interactions

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Correlation between UV Raman intensity and hydrogen bonding of the adenine ring2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Correlation between UV Raman Intensity and Hydrogen Bonding of the Adenine Ring2005

Author(s)

Journal Title

Data Source

[Journal Article] Isotope-edited UV Raman spectroscopy of protein-DNA interactions : Binding modes of cyclic AMP receptor protein to a natural DNA recognition site2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Correlation between UV Raman intensity and hydrogen bonding of the adenine ring2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Isotope-edited UV Raman spectroscopy of protein-DNA interactions : Binding modes of cyclic AMP receptor protein to a natural DNA recognition site

Author(s)

Journal Title

Data Source

TOYAMA Akira 外山聡