Hazama Akihiro 挾間章博

… Alternative Names

HAZAMA Akihiro 挾間章博

挟間章博ハザマアキヒロ

狭間章博ハザマアキヒロ

挾間章博ハザマアキヒロ

Less

Researcher Number	60218394
Other IDs
Affiliation (Current)	2022: 福島県立医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2014 – 2016: 福島県立医科大学, 医学部, 教授 2003 – 2010: 福島県立医科大学, 医学部, 教授 2000 – 2001: 岡崎国立共同研究機構, 統合バイオサイエンスセンター, 助教授 1999: 岡崎国立共同研究機構, 基礎生物学研究所, 助教授 1994 – 1998: 岡崎国立共同研究機構, 生理学研究所, 助手 1993: 岡崎国立共同研究機構, 生理学研究所・細胞器管研究系・機能協関部門, 助手
Review Section/Research Field	Principal Investigator General physiology / General physiology / Science and Engineering Except Principal Investigator Otorhinolaryngology / General physiology / Otorhinolaryngology
Keywords	Principal Investigator amphotericin B / イオンチャネル / C6 / HT29 / CFTR / クロライドチャネル / ATP / 塩素イオン / 細胞保護 / チャネル … More / ion channel / グルタミン酸 / 細胞膨張 / 低浸透圧 / グリア / cell swelling / glia / Cl-channel / ナトリウム・ミオイノシトール共輸送体 / ミオイノシトール / アフリカツメガエル / C1チャネル / 内因性イオンチャネル阻害物質 / クロライトチャネル / ORCC / 発現クローニング法 / 低分子量GTP結合蛋白 / プラバスタチン / SPQ / cAMP / 低分子量GTP結合蛋白質 / 内分泌撹乱物質 / ステロイド / CIチャネル / 水チャネル / 水銀 / 細胞死 / ネクローシス / リソソーム / 細胞傷害 / 塩素 / セシウム / HeLa細胞 / 細胞増殖 / HeLa / 細胞増殖抑制 / 輸送体 / トランスポータ / Cs / transporter / 虚血 / クロライド / glutamic acid / hyototonic / ischemia / channek / chioride / アクアポリン / Cl-チャネル / グリオーマ / CL-チャンネル / グルコース / アミノ酸 / glutamamic acid / aquanorin / 動脈硬化 / C1-チャネル / 血管内皮細胞 / 高NaCl食 / Cl-チャネル阻害剤 / 細胞障害 / 塩素シオン / atherosclerosis / endothelial cells / cvto-protection / high NaC1 diet / Cl-channel blocker … More Except Principal Investigator パッチクランプ / 移植・再生医療 / 頭頸部 / ATP / サイクリックAMP / cyclic AMP / CFTR / 気道分泌 / イオンチャンネル / ウッシングチャンバー / 気道上皮 / モルモット気管 / 繊毛細胞 / 無繊毛細胞 / 細胞・組織 / バイオテクノロジー / 線維芽細胞 / 細胞容積調節 / Cl-チャネル / P糖蛋白 / アクチン / Cl^-チャネル / C1^-チャネル / Cキナーゼ / Mg / 容積感受性C1^-チャネル / パッチ・クランプ / ダブル・パッチ・クランプ / cell volume regulation / C1^- channel / P-glycoprotein / actin / Patch-clamp / パネト細胞 / CI^-分泌 / Cl分泌 / Paneth cell / ClィイD1-ィエD1 / patch-clamp / 血管新生 / 組織修復 / 臓器再生 / regenerative medicine / neo-vascularization / tissue repair Less

Finding the cesium permeation pathway of cell membrane which contributes the accumulation of cesium into the organs.Principal Investigator
- Principal Investigator
  
  Hazama Akihiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Fukushima Medical University
Cytoprotection against necrotic cell death by the stabilization of the lysosomePrincipal Investigator
- Principal Investigator
  
  HAZAMA Akihiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Fukushima Medical University
Technology of multi-layered tissue engineering for the head and neck organs
- Principal Investigator
  
  OMORI Koichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Fukushima Medical University
The Research on the ion channels which are involved in the cytoprotective medianisms of endothelial cells in the atherosclerotic model animalPrincipal Investigator
- Principal Investigator
  
  HAZAMA Akihiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Fukushima Medical University
Mechanism of neo-vascularization and tissue repair for regeneration of head and neck organs
- Principal Investigator
  
  OMORI Koichi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Fukushima Medical University
The regulatory mechanism of amino acid release form swollen cells by aquaporinsPrincipal Investigator
- Principal Investigator
  
  HAZAMA Akihiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Fukushima Medical University
内分泌撹乱物質を検出するバイオ分子センサーの開発Principal Investigator
- Principal Investigator
  
  挾間章博
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Science and Engineering
- Research Institution
  Okazaki National Research Institutes
Molecular indentification of the pathway for amino acids relased from swollen cellPrincipal Investigator
- Principal Investigator
  
  HAZAMA Akihiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Okazaki National Research Institutes,Center for Integrative Bioscience
CFTR Cl-チャネルの低分子量GTP結合蛋白質による形質膜発現制御機構の解明Principal Investigator
- Principal Investigator
  
  挟間章博
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General physiology
- Research Institution
  Okazaki National Research Institutes
Molecular Cell Physiological Study on Paneth Cell Function
- Principal Investigator
  
  OKADA Yasunobu
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  National Institute for Physiological Sciences
発現クローニング法による内在性クロライドチャネル阻害因子の同定Principal Investigator
- Principal Investigator
  
  狭間章博
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General physiology
- Research Institution
  Okazaki National Research Institutes
レギュレーターとしてのCFTRPrincipal Investigator
- Principal Investigator
  
  狭間章博
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Okazaki National Research Institutes
気道分泌にかかわるイオンチャンネルの分子的制御機構
- Principal Investigator
  
  三輪正人
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Fujita Health University
内因性C1チャンネル阻害物質の分子的同定Principal Investigator
- Principal Investigator
  
  挾間章博
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General physiology
- Research Institution
  Okazaki National Research Institutes
Molecular Cell Physiological Study on Volume-Sensitive C1^- Channel
- Principal Investigator
  
  OKADA Yasunobu
- Project Period (FY)
  1994 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General physiology
- Research Institution
  Okazaki National Research Institutes National Institute for Physiological Sciences
ナトリウム・ミオイノシトール共輸送体の分子生物学的・電気生理学的研究Principal Investigator
- Principal Investigator
  
  挾間章博
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General physiology
- Research Institution
  Okazaki National Research Institutes

All 2017 2016 2015 2012 2011 2010 2008 2007 2005 2004

All Journal Article Presentation

[Journal Article] Cesium reversibly suppresses HeLa cell proliferation by inhibiting cellular metabolism.2017
- Author(s)
  Kobayashi D, Kakinouchi K, Nagae T, Nagai T, Shimura K, Hazama A.
- Journal Title
  
  FEBS Lett.
  
  Volume: 591 Pages: 718-727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460299
[Journal Article] Plasma membrane aquaporin AqpZ protein is essential for glucose metabolism during photomixotrophic growth of Synechocystis2011
- Author(s)
  Akai M, Onai K, Kusano M, Sato M, Redestig H, Toyooka K, Morishita M, Miyake H, Hazama A, Checchetto V, Szabo I, Matsuoka K, Saito K, Yasui M, Ishiura M, Uozumi N.
- Journal Title
  
  J Biol Chem
  
  Volume: 15(286) Pages: 25224-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590211
[Journal Article] Improved islet yield and function by use of a chloride channel blocker during collagenase digestion2011
- Author(s)
  Anazawa T, Sato Y, Saito T, Tsuchiya T, Kenjo A, Kimura T, Haga J, Miyake M, Waguri S, Hazama A, Gotoh M.
- Journal Title
  
  Transplantation
  
  Volume: 27(92) Pages: 871-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590211
[Journal Article] The effect of topical amiloride eye drops on tear quantity in rabbits2010
- Author(s)
  Hara S, Hazama A, Miyake M, Kojima T, Sasaki Y, Shimazaki J, Dogru M, Tsubota K
- Journal Title
  
  Molecular Vision
  
  Volume: 16 Pages: 2279-2285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590211
[Journal Article] The effect of topical amiloride eye drops on tear quantity in rabbits2010
- Author(s)
  Hara S, Hazama A, Miyake M, Kojima T, Sasaki Y, Shimazaki J, Dogru M, Tsubota K.
- Journal Title
  
  Mol Vis
  
  Volume: 4(16) Pages: 2279-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590211
[Journal Article] A tissue-engineered trachea derived from a framed collagen scaffold, gingival fibroblasts and adipose-derived stem cells.2010
- Author(s)
  Kobayashi K, Suzuki T, Nomoto Y, Tada Y, Miyake M, Hazama A, Wada I, Nakamura T, Omori K.
- Journal Title
  
  Biomaterials
  
  Volume: 31(18) Pages: 4855-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590211
[Journal Article] A tissue-engineered trachea derived from a framed collagen scaffold, gingival fibroblasts and adipose-derived stem cells2010
- Author(s)
  Kobayashi K, Suzuki T, Nomoto Y, Tada Y, Miyake M, Hazama A, Wada I, Nakamura T, Omori K
- Journal Title
  
  Biomaterials
  
  Volume: 18 Pages: 4855-4863
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590211
[Journal Article] Deep-sea water improves cardiovascular hemodynamics in Kurosawa and Kusanagi-Hypercholesterolemic (KHC) rabbits2008
- Author(s)
  Katsuda, S., Yasukawa, T., Nakagawa, K., Miyake, M., Yamasaki, M., Katahira, K., Mohri, M., Shimizu, T., Hazama, A
- Journal Title
  
  Biol Pharm Bull 31
  
  Pages: 38-44
- NAID
  110006569971
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590206
[Journal Article] Deep-sea water improves cardiovascular hemodynamics in Kurosawa and Kusanagi-Hypercholesterolemic (KHC) rabbits.2008
- Author(s)
  Katsuda S, Yasukawa T, Nakagawa K, Miyake M, Yamasaki M, Katahira K, Mohri M, Shimizu T, Hazama A.
- Journal Title
  
  Biological & pharmaceutical bulletin 31
  
  Pages: 38-44
- NAID
  110006569971
- Data Source
  KAKENHI-PROJECT-18590206
[Journal Article] Deep-sea water improves cardiovascular hemodynamics in Kurosawa and Kusanagi-Hypercholesterolemic (KHC) rabbits2008
- Author(s)
  Katsuda S, Yasukawa T, Nakagawa K, Miyake M, Yamasaki M, Katahira K, MohriM, Shimizu T, Hazama A.
- Journal Title
  
  Biological & pharmaceutical bulletin 31
  
  Pages: 38-44
- NAID
  110006569971
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590206
[Journal Article] Potential of heterotopic fibroblasts as autologous transplanted cells for tracheal epithelial regeneration.2007
- Author(s)
  Kobayashi K, Suzuki T, Nomoto Y, Tada Y, Miyake M, Hazama A, Nakamura T, Omori K.
- Journal Title
  
  Tissue engineering 13
  
  Pages: 2175-2184
- Data Source
  KAKENHI-PROJECT-18590206
[Journal Article] Potential of heterotopic fibroblasts as autologous transplanted cells for tracheal epithelial regeneration2007
- Author(s)
  Kobayashi K, Suzuki T, Nomoto Y, TadaY, Miyae M, Hazama A, Nakamura T, Omori K
- Journal Title
  
  Tissue Engineering 13(9)
  
  Pages: 2175-2184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390437
[Journal Article] Conversion of aquaporin 6 from an anion channel to a water-selective channel by a single amino acid substitution.2005
- Author(s)
  Liu K, Kozono D, Kato Y, Agre P, Hazama A, Yasui M
- Journal Title
  
  Proc Natl Acad Sci U S A 102
  
  Pages: 2192-2197
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590202
[Journal Article] Conversion of aquaporin 6 from an anion channel to a water-selective channel by a single amino acid substitution.2005
- Author(s)
  Liu K, Kozono D, Kato Y, Agre P, Hazama A, Yasui M.
- Journal Title
  
  Proceedings of the National Academy of Science, USA. 102
  
  Pages: 2192-2197
- Data Source
  KAKENHI-PROJECT-15590202
[Journal Article] Conversion of aquaporin6from an anion channel to a water-selective channel by a single amino acid substitution2005
- Author(s)
  Liu K, Kozono D, Kato Y, Agre P, Hazama A, Yasui M
- Journal Title
  
  Proc Natl Acad Sci USA. 102
  
  Pages: 2192-2197
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590202
[Journal Article] Detecting ATP release by a biosensor method2004
- Author(s)
  Hayashi S, Hazama A, Dutta AK, Sabirov RZ, Okada Y
- Journal Title
  
  Science STKE 258
  
  Pages: 14-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590202
[Presentation] セシウムがHeLa細胞の代謝酵素発現に与える影響2017
- Author(s)
  挾間章博、熊谷悠、久米佑佳、小林大輔
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  浜松
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-26460299
[Presentation] Suppression of the HeLa cell proliferation by Cs without the effect on the membrane potential2016
- Author(s)
  挾間章博
- Organizer
  第９３回日本生理学会大会
- Place of Presentation
  札幌
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-26460299
[Presentation] Csによる細胞増殖阻害時に何が起こっているか？2015
- Author(s)
  小林大輔、垣野内景、長江智紀、挾間章博
- Organizer
  日本生理学会
- Place of Presentation
  神戸
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-26460299
[Presentation] Cs+イオンの細胞増殖抑制効果における細胞種依存性の検討2015
- Author(s)
  垣野内景、小林大輔、挾間章博
- Organizer
  日本生理学会
- Place of Presentation
  神戸
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-26460299
[Presentation] セシウムは細胞増殖を抑制する2012
- Author(s)
  小林大輔、垣野内景、松村香楠、挾間章博
- Organizer
  細胞統合生理日本生理学会大会
- Data Source
  KAKENHI-PROJECT-20590211
[Presentation] ウシ卵細胞における膜電位分布解析2012
- Author(s)
  三宅将生、宮村元晴、濱野晴三、兼子智、挾間章博
- Organizer
  日本生理学会大会
- Data Source
  KAKENHI-PROJECT-20590211
[Presentation] リソソーム安定化機構と細胞死2011
- Author(s)
  挾間章博, 三宅将生
- Organizer
  福島医大・医・細胞統合生理日本生理学会大会
- Data Source
  KAKENHI-PROJECT-20590211
[Presentation] アンフォテリシンB誘導性ネクローシスにおける細胞骨格の役割2010
- Author(s)
  三宅将生、挾間章博
- Organizer
  福島医大・医・細胞統合生理日本生理学会大会
- Data Source
  KAKENHI-PROJECT-20590211

1. NAKAMURA Tatsuo (70227908)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. WADA Ikuo (40182969)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. KATSUDA Shin-ichiro (80285022)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
4. MIYAKE Masao (00381385)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
5. OMORI Koichi (10233272)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. KOBAYASHI Daisuke (40528080)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
7. OKADA Yasunobu (10025661)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. MATSUZUKA Takashi (80336461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YOKOYAMA Shuji (80381408)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YAMASAKI Masao (10192395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. 三輪正人 (80247650)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 岩田重信 (90084558)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 富永真琴 (90260041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 樫原康博 (00161018)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 老木成稔 (10185176)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 高橋充 (80338805)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Hazama Akihiro 挾間 章博

HAZAMA Akihiro 挾間 章博

挟間 章博 ハザマ アキヒロ

狭間 章博 ハザマ アキヒロ

挾間 章博 ハザマ アキヒロ

Research Projects

Research Products

Co-Researchers

Finding the cesium permeation pathway of cell membrane which contributes the accumulation of cesium into the organs.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cytoprotection against necrotic cell death by the stabilization of the lysosomePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Technology of multi-layered tissue engineering for the head and neck organs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The Research on the ion channels which are involved in the cytoprotective medianisms of endothelial cells in the atherosclerotic model animalPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of neo-vascularization and tissue repair for regeneration of head and neck organs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The regulatory mechanism of amino acid release form swollen cells by aquaporinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

内分泌撹乱物質を検出するバイオ分子センサーの開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular indentification of the pathway for amino acids relased from swollen cellPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

CFTR Cl-チャネルの低分子量GTP結合蛋白質による形質膜発現制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular Cell Physiological Study on Paneth Cell Function

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

発現クローニング法による内在性クロライドチャネル阻害因子の同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

レギュレーターとしてのCFTRPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

気道分泌にかかわるイオンチャンネルの分子的制御機構

Hazama Akihiro 挾間章博

HAZAMA Akihiro 挾間章博

挟間章博ハザマアキヒロ

狭間章博ハザマアキヒロ

挾間章博ハザマアキヒロ