EZAKI Junji 江崎淳二

… Alternative Names

江崎淳二エザキジユンジ

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Researcher Number	60232948
Other IDs
External Links
Affiliation (Current)	2025: 順天堂大学, 医学部, 非常勤講師
Affiliation (based on the past Project Information) *help	2007 – 2008: 順天堂大学, 医学部, 准教授 2004 – 2005: 順天堂大学, 医学部, 講師 2001: Juntendo University, School of Medicine, Assistant Professor, 医学部, 講師 1998 – 2000: 順天堂大学, 医学部, 助手 1992 – 1993: 順天堂大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Pathological medical chemistry / 代謝生物化学 Except Principal Investigator Pathological medical chemistry / Functional biochemistry / General medical chemistry
Keywords	Principal Investigator TPP-I / Cln6p / Cln3p / Cln2p / CLN2 / beta-COP / coated vesicle / lgp120 / PCR / adaptin … More / lysosome / peroxisome / autophagy / autophagosome / proteolipid / neurodegenerative disease / Cln8p / Cln5p / Cln3P / Atg7 / オートファジー / ペルオキシソーム / オートファージ / オートファゴソーム / プロテオリピド / 神経性疾患 / subunit c / Iysosome / Batten disease / サブユニットc / リソソーム / Batten病 / coat protein / リソゾーム膜蛋白質 / リソゾーム / β-COP … More Except Principal Investigator リソソーム / exosome / secretory lysosome / lysosome / ATP synthase / Subunit c / タンパク分解 / ATP合成酵素 / ノックアウトマウス / オートファジー / protein degradation / ATG genes / melanogenesis / melanosome / autophagy / プロテオリシス / メラノーマ / メラニン / オートファゴソーム / エキソソーム / ATG遺伝子 / メラニン形成 / メラノソーム / cathepsin / tripeptidyl peptidase I / neuronal ceroid lipofuscinosis / カテプシンD / TPP-I / サブユニットc蓄積 / 神経性セロイド様リポフスチン蓄積症 / 神経変性疾患 / Delay of degradation / Lysosomal storage / batten disease / Mitochondria / サブユニット蓄積症 / 分解遅延 / リソソーム内蓄積 / Batten病 / ミトコンドリア / サブユニットC / トリアシルグリセロール / Atg7 / 脂質代謝 / Lipid droplet / 細胞分化 / 脂肪細胞 / 脂肪滴(Lipid droplet) Less

The role of autophagy in adipocyte-differentiation and lipid metabolism
- Principal Investigator
  
  KOMINAMI Eiki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Juntendo University
Secretory lysosome : the roles of ATG gene products
- Principal Investigator
  
  UENO Takashi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  JUNTENDO UNIVERSITY
Proteolipid storage disease causing neurodegeneration : Research from the lysosomal membraneproteins.Principal Investigator
- Principal Investigator
  
  EZAKI Junji
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  JUNTENDO UNIVERSITY
LYSOSOMAL PROTEIN STORAGE DISEASE
- Principal Investigator
  
  KOMINAMI Eiki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  JUNTENDO UNIVERSITY
The Study about the Molecular Mechanism of Batten DiseasePrincipal Investigator
- Principal Investigator
  
  EZAKI Junji
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Juntendo University
Molecular mechanism of pathogenesis of Batten disease
- Principal Investigator
  
  KOMINAMI Eiki
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Juntendo University School of Medicine
The role of beta-COP like membrane protein in lysosome formationPrincipal Investigator
- Principal Investigator
  
  EZAKI Junji
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  Juntendo University School of Medicine

All 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book

[Book] Methods in Enzymology, Chapter 14“Method for Monitoring Pexophagy in Mammalian Cell"2009
- Author(s)
  Ezaki J., et al.
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-19390079
[Book] Methods Enzymol2009
- Author(s)
  Ezaki J, Komatsu M, Yokota S, Ueno T, Kominami E
- Publisher
  Method for monitoring pexophagy in mammalian cells
- Data Source
  KAKENHI-PROJECT-19390079
[Journal Article] Comprehensive proteomicsanalysis of autophagy-deficient mouseliver2008
- Author(s)
  Matsumoto N, Ezaki J, Komatsu M, Takahashi K, Mineki R, Taka H, Kikkawa M, Fujimura T, Takeda-Ezaki M, Ueno T, Tanaka K, Kominami E
- Journal Title
  
  Biochem Biophys Res Commun 368(3)
  
  Pages: 643-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390079
[Journal Article] Structural basis for sorting mechanism of p62 in selective autophagy2008
- Author(s)
  Ichimura Y, Kumanomidou T, Sou YS, Mizushima T, Ezaki J, Ueno T, Kominami E,Yamane T, Tanaka K, Komatsu M
- Journal Title
  
  J Biol Chem 283(33)
  
  Pages: 22847-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390079
[Journal Article] Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice2007
- Author(s)
  Komatsu M, Waguri S, Koike M, Sou YS, Ueno T, Hara T, Mizushima N, Iwata J, Ezaki J, Murata S, Hamazaki J, Nishito Y, Iemura S, Natsume T, Yanagawa T, Uwayama J, Warabi E, Yoshida H, Ishii T, Kobayashi A, Yamamoto M, Yue Z, Uchiyama Y, Kominami E, Tanaka K
- Journal Title
  
  Cell 131(6)
  
  Pages: 1149-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390079
[Journal Article] Excess peroxisomes are degraded by autophagic machinery in mammals.2006
- Author(s)
  Iwata J, Ezaki J, Komatsu M, Yokota S, Ueno T, Tanida I, Chiba T, Tanaka K, Kominami E.
- Journal Title
  
  J Biol Chem. 281(7)
  
  Pages: 4035-404
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370063
[Journal Article] Excess peroxisomes are degraded by autophagic machinery in mammals.2006
- Author(s)
  J.Iwata, J.Ezaki, M.Komatsu, S.Yokota, T.Ueno, I.Tanida, T.Chiba, K.Tanaka, E.Kominami
- Journal Title
  
  J.Biol.Chem. 281
  
  Pages: 4035-4041
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590253
[Journal Article] Impaiment of starvation-induced and constitutive autophagy in Atg7-deficient mice.2005
- Author(s)
  M.Komatsu, S.Wguri, T.Ueno, J.Iwata, S.Murata, I.Tanida, J.Ezaki, N.Mizushima, Y.Ohsumi, Y.Uchiyama, E.Kominami, K.Tanaka, T.Chiba
- Journal Title
  
  J.Cell Biol. 169
  
  Pages: 425-454
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590253
[Journal Article] Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice.2005
- Author(s)
  Komatsu M, Waguri S, Ueno T, Iwata J, Murata S, Tanida I, Ezaki J, Mizushima N, Ohsumi Y, Uchiyama Y, Kominami E, Tanaka K, Chiba T.
- Journal Title
  
  J Cell Biol. 169(3)
  
  Pages: 425-434
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370063
[Journal Article] The Intracellular Localization and Function of Proteins of Neuronal Ceroid Lipofuscinoses2004
- Author(s)
  Ezaki Junji et al.
- Journal Title
  
  Brain Pathology 14
  
  Pages: 77-85
- Data Source
  KAKENHI-PROJECT-16590253
[Journal Article] HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates.2004
- Author(s)
  Tanida I, Sou YS, Ezaki J, Minematsu-Ikeguchi N, Ueno T, Kominami E.
- Journal Title
  
  J Biol Chem. 279(35)
  
  Pages: 36268-36276
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370063
[Journal Article] HsAtg4B/HsApg4B/Autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtuble-associated protein light chain3- and GABA receptor-associated protein-phospholipid conjugates2004
- Author(s)
  I.Tanida, Y.Sou, J.Ezaki, N.Minematsu-Ikeguchi, T.Ueno, E.Kominami
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 36268-36276
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590253
[Journal Article] The intracellular localization and function of protein of neuronal ceroid lipouscinoses.2004
- Author(s)
  J.Ezaki, E.Kominami
- Journal Title
  
  Brain Pathol. 14
  
  Pages: 77-85
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590253
[Journal Article] The Intracellular Localization and Function of Proteins of Neuronal Ceroid Lipofuscinoses2004
- Author(s)
  Ezaki Junji, et al.
- Journal Title
  
  Brain Paythology 14
  
  Pages: 77-85
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590253
[Journal Article] Mutation of the glycosylated asparagines residue 286 in human CLN2 protein results in loss of enzymatic activity.2004
- Author(s)
  K.Tsiakas, R.Steinfeld, S.Storch, J.Ezaki, Z.Lukacs, E.Kominami, A.Kohlshutter, K.Ullrich, T.Braulke
- Journal Title
  
  Glycobiology 14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590253
[Journal Article] Characterization of Cin3p,the gene product responsible for juvenile neuronal ceroid lipofuscinosis, as a lysosomal integral membrane glycoprotein.2003
- Author(s)
  Ezaki Junji, et al.
- Journal Title
  
  J.Neurochem. 87
  
  Pages: 1296-1308
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590253
[Journal Article] Characterization of Cln3p, the gene product responsible for juvenile neuronal ceroid lipofuscinosis, as a lysosomal integral membrane glycoprotein.2003
- Author(s)
  J.Ezaki, I.M.Takeda-Ezaki, M.Koike, Y.Ohsawa, H.Taka, R.Mineki, K.Murayama, Y.Uchiyama, T.Ueno, E.Kominami
- Journal Title
  
  J.Neurochem. 87
  
  Pages: 1296-1308
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590253
[Presentation] Autophagosome formation resoponse to nutrient starvatior2007
- Author(s)
  Ezaki J
- Organizer
  Keystone Symposium on Autophagy in Health and Disease
- Place of Presentation
  Monterey, California, USA
- Year and Date
  2007-04-19
- Data Source
  KAKENHI-PROJECT-19390079
[Presentation] Autophagosome formation in the starved animal2007
- Author(s)
  Ezaki J
- Organizer
  第30回日本分子生物学年会・第80回日本生化学回大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19390079
[Presentation] Autophagosome formation resoponse to nutrient starvatior2007
- Author(s)
  Ezaki J., et. al.
- Organizer
  Keystone Symposium on Autophagy in Health and Disease
- Place of Presentation
  Monterey,California,USA
- Year and Date
  2007-04-19
- Data Source
  KAKENHI-PROJECT-19390079
[Presentation] Autophagosome formation resoponse to nutrient starvation2007
- Author(s)
  Ezaki J., et. al.
- Organizer
  Gordon Reseazch Conferemces on Autophagy in stress, Development and disease
- Place of Presentation
  Ventura,CA,USA
- Year and Date
  2007-01-09
- Data Source
  KAKENHI-PROJECT-19390079
[Presentation] Autophagosome formation resoponse to nutrientstarvation
- Author(s)
  Ezaki J
- Organizer
  Gordon Research Conferemceson Autophagy in stress, Development and disease January
- Place of Presentation
  Ventura, CA, USA
- Data Source
  KAKENHI-PROJECT-19390079

1. KOMINAMI Eiki (10035496)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
2. TANIDA Isei (30296868)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
3. NORIHIKO Furuya (50401188)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. ISHIDOH Kazumi (40212906)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. UENO Takashi (10053373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

EZAKI Junji 江崎 淳二

江崎 淳二 エザキ ジユンジ

Research Projects

Research Products

Co-Researchers

The role of autophagy in adipocyte-differentiation and lipid metabolism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Secretory lysosome : the roles of ATG gene products

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Proteolipid storage disease causing neurodegeneration : Research from the lysosomal membraneproteins.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

LYSOSOMAL PROTEIN STORAGE DISEASE

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The Study about the Molecular Mechanism of Batten DiseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism of pathogenesis of Batten disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of beta-COP like membrane protein in lysosome formationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Methods in Enzymology, Chapter 14“Method for Monitoring Pexophagy in Mammalian Cell"2009

Author(s)

Publisher

Data Source

[Book] Methods Enzymol2009

Author(s)

Publisher

Data Source

[Journal Article] Comprehensive proteomicsanalysis of autophagy-deficient mouseliver2008

Author(s)

Journal Title

Data Source

[Journal Article] Structural basis for sorting mechanism of p62 in selective autophagy2008

Author(s)

Journal Title

Data Source

[Journal Article] Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice2007

Author(s)

Journal Title

Data Source

[Journal Article] Excess peroxisomes are degraded by autophagic machinery in mammals.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Excess peroxisomes are degraded by autophagic machinery in mammals.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Impaiment of starvation-induced and constitutive autophagy in Atg7-deficient mice.2005

Author(s)

Journal Title

EZAKI Junji 江崎淳二

江崎淳二エザキジユンジ