OHTA Tomohiko 太田智彦

Researcher Number	60233136
Other IDs
External Links
Affiliation (Current)	2025: 聖マリアンナ医科大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 聖マリアンナ医科大学, 医学研究科, 教授 2010 – 2015: St.Marianna University School of Medicine, 医学(系)研究科(研究院), 教授 2007 – 2009: St.Marianna University School of Medicine, Department of Surgery, Associate Professor 2004 – 2006: 聖マリアンナ医科大学, 医学部, 助教授 1999 – 2003: St.Marianna University School of Medicine, Department of Surgery, Assistant Professor, 医学部, 講師 1994 – 1998: St.Marianna University, 1st Department of Surgery, Associate, 医学部, 助手
Review Section/Research Field	Principal Investigator Biological Sciences / General surgery / General surgery / Basic Section 55010:General surgery and pediatric surgery-related / Obstetrics and gynecology / Tumor biology / Biological Sciences / Tumor diagnosis Except Principal Investigator General surgery / Digestive surgery
Keywords	Principal Investigator BRCA1 / BARD1 / DNA損傷 / DNA修復 / RINGフィンガー / ユビキチンリガーゼ / 家族性乳癌 / 乳癌 / RPB8 / ユビキチン … More / Nucleophosmin / RING finger / 変異 / 細胞周期 / KDM4B / ubiquitin ligase / familial breast cancer / ヘテロクロマチン / エストロゲン / ubiquitin / 薬剤感受性 / DUB / HERC2 / 癌 / cGAS-STING / RSK / 免疫チェックポイント / HER2 / ER / 内分泌療法 / AKT / Fbxo22 / 子宮内膜がん / 乳がん / G4安定化剤 / グアニン4重鎖 / 相同組換修復 / 卵巣癌 / 膵癌 / 臓器特異性 / Chk2 / アポトーシス / 染色体不安定性 / ERα / Nucleophosm / nucleophosmin / ヌクレオフォスミン / Ligase / breast cancer / ヘテロダイマー / タンパク質分解 / 卵管癌 / 治療 / 非癌遺伝子依存性 / 癌化学療法 / 合成致死性 / DNA複製 / NPM1 / Basal-like 乳癌 / 術前化学療 / 術前化学療法 / Basal-like乳癌 / チェックポイント / チェックポイン / CDK2 / ユビキンリガーゼ / p27 / cdc2 variant / G0期 / Rb / Cyclin / cdk / G0静止 … More Except Principal Investigator p53 / APC / 家族性大腸ポリポーシス / EDD / hyd / scFv / CDK2ΔT / T-loop / variant / breast cancer / 細胞周期 / western blotting / c-erbB-2 / p34^<cdc2> / 乳癌 / colon cancer / tumor suppressor / 大腸癌 / 癌抑制遺伝子 / RING finger / ubiquitin ligase / protein degradation / gene therapy / RINGフィンガー / ユビキチンリガーゼ / ScFv / タンパク質分解 / 遺伝子治療 / CDC2ΔT / cell cycle / RT-PCR / Δcdk2 / Δcdc2 / p21 / cdk2 / cdc2 / CDK2 / CDC2 / mammography / immunostaining / non-palpable breast cancer / カテプシンD / c-erbB / P34^<cdc2> / マンモグラフィ / 免疫染色 / 非触知 Less

乳がんのDNA損傷修復とcGAS-STING経路を制御するシグナル伝達系の解析Principal Investigator
- Principal Investigator
  
  太田智彦
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  St. Marianna University School of Medicine
Study of the mechanism underlying the acquired hormone therapy resistance in breast cancerPrincipal Investigator
- Principal Investigator
  
  Ohta Tomohiko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  St. Marianna University School of Medicine
Analyses of the mechanisms for DNA G-quadruplex resolution as a molecular basis of the treatment of breast and ovarian cancer.Principal Investigator
- Principal Investigator
  
  Ohta Tomohiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  St. Marianna University School of Medicine
A study of mechanism underlying carcinogenesis promoted by estrogen receptor in BRCA1 deficient cellsPrincipal Investigator
- Principal Investigator
  
  OHTA Tomohiko
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  St. Marianna University School of Medicine
Functional analysis of BRCA1 as the molecular basis of breast cancer therapyPrincipal Investigator
- Principal Investigator
  
  OHTA Tomohiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  St. Marianna University School of Medicine
Unravelling the mechanism of ovarian carcinogenesis caused by BRCA1 depletion and estrogen actionPrincipal Investigator
- Principal Investigator
  
  OHTA Tomohiko
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  St. Marianna University School of Medicine
Regulation of DNA repair machinery by K6- and K63-linked polyubiquitin chainsPrincipal Investigator
- Principal Investigator
  
  OHTA Tomohiko
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  St. Marianna University School of Medicine
DNA相同組替え修復機構におけるBRCA1ユビキチンリガーゼ活性の役割Principal Investigator
- Principal Investigator
  
  太田智彦
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  St. Marianna University School of Medicine
Research on the breast cancer chemotherapy targeting synthetic lethality caused by the factors in the DNA damage repair pathways.Principal Investigator
- Principal Investigator
  
  OHTA Tomohiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor diagnosis
- Research Institution
  St. Marianna University School of Medicine
BRCA1ユビキチンリガーゼによるDNA損傷応答Principal Investigator
- Principal Investigator
  
  太田智彦
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  St. Marianna University School of Medicine
HERC2によるS期およびG2/M期チェックポイント制御機構の解析Principal Investigator
- Principal Investigator
  
  太田智彦
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  St.Marianna University School of Medicine
Analyses of DNA damage response to neoadjuvant chemotherapy in basal-like breast cancerPrincipal Investigator
- Principal Investigator
  
  OHTA Tomohiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  St.Marianna University School of Medicine
BRCA1ユビキチンリガーゼによる乳癌抑制機構の解析Principal Investigator
- Principal Investigator
  
  太田智彦
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  St.Marianna University School of Medicine
Study of DNA repair mechanisms that affect chemosensitivity of breast cancerPrincipal Investigator
- Principal Investigator
  
  OHTA Tomohiko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  St.Marianna University School of Medicine
The Role in APC stability control mechanism by EDD
- Principal Investigator
  
  OTSUBO Takehito
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  St.Marianna University School of Medicine
細胞周期におけるBRCA1-BARD1ユビキチンリガーゼ活性の調節機構Principal Investigator
- Principal Investigator
  
  太田智彦
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  St. Marianna University School of Medicine
Mechanisms that regulate chromosomal stability through the ubiquitin lipase activity of BRCA1Principal Investigator
- Principal Investigator
  
  OHTA Tomohiko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  St.Marianna University School of Medicine
ユビキチンリガーゼBRCA1-BARD1によるDNA修復および転写の制御Principal Investigator
- Principal Investigator
  
  太田智彦
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  St. Marianna University School of Medicine
BRCA1-BARD1ヘテロダイマーユビキチンリガーゼによる細胞周期制御Principal Investigator
- Principal Investigator
  
  太田智彦
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  St. Marianna University School of Medicine
Selective degradation of p53 mutant by an engineered ScFv-linked ubiquitin ligase
- Principal Investigator
  
  FUKUDA Mamoru
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  St. Marianna University School of Medicine
Elucidation of substrates and analysis of the function of BRCA 1 ubiquitin ligasePrincipal Investigator
- Principal Investigator
  
  TOMOHIKO Ohta
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  St. Marianna University School of Medicine
Molecular Cloning and Functional Analysis of CDK Variant Expressed in Breast Cancer Tissues
- Principal Investigator
  
  FUKUDA Mamoru
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  St.Marianna University School of Medicine
静止期癌細胞の細胞周期導入時においてG1/Sに先行する未知のG0/G1 eventPrincipal Investigator
- Principal Investigator
  
  太田智彦
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General surgery
- Research Institution
  St. Marianna University School of Medicine
癌細胞におけるLRP蛋白細胞外ドメインの糖鎖形成不全と細胞増殖抑制との関係Principal Investigator
- Principal Investigator
  
  太田智彦
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General surgery
- Research Institution
  St. Marianna University School of Medicine
Proliferative activities of non-palpable breast cancer detected by mammography
- Principal Investigator
  
  FUKUDA Mamoru, 福田護
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  St.Marianna University

[Book] 乳癌診療 state of the art - 科学に基づく最新診療「遺伝性乳癌に対する遺伝子修復不全標的治療」2022
- Author(s)
  太田智彦
- Total Pages
  5
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-20H03748
[Book] Hereditary Breast and Ovarian Cancer「Molecular Basis of BRCA1 and BRCA2: Homologous Recombination Deficiency and Tissue-Specific Carcinogenesis」2021
- Author(s)
  Ohta T, Wu W
- Total Pages
  15
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-20H03748
[Book] 乳腺腫瘍学「7. BRCA変異診断、ゲノム診断」2020
- Author(s)
  太田智彦
- Total Pages
  4
- Publisher
  金原出版
- Data Source
  KAKENHI-PROJECT-20H03748
[Book] 医学のあゆみ「BRCA遺伝子変異による臓器特異的な発がん」2020
- Author(s)
  郷田敦史, 呉文文, 太田智彦
- Total Pages
  5
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-20H03748
[Book] メディカル・サイエンス・ダイジェスト「DNA相同組換え修復とユビキチン」2019
- Author(s)
  朱明章, 太田智彦
- Total Pages
  4
- Publisher
  ニュー・サイエンス社
- Data Source
  KAKENHI-PROJECT-17H03585
[Book] がん分子標的治療「がん治療分子標的としてのDNA相同組み換え修復異常」2019
- Author(s)
  朱明章, 呉文文, 太田智彦
- Total Pages
  8
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-17H03585
[Book] BRCA1/2の基礎とPARP阻害剤2018
- Author(s)
  太田智彦.
- Total Pages
  9
- Publisher
  乳癌の臨床
- Data Source
  KAKENHI-PROJECT-17H03585
[Book] 臨床医のための乳腺基礎医学「乳癌におけるDNA損傷と修復不全」2018
- Author(s)
  頼勇強, 太田智彦
- Total Pages
  5
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-17H03585
[Book] 臨床医のための乳腺基礎医学「乳癌におけるDNA損傷と修復不全」2018
- Author(s)
  頼勇強, 太田智彦
- Total Pages
  5
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-16K15712
[Book] BRCA1/2の基礎とPARP阻害剤2018
- Author(s)
  太田智彦
- Total Pages
  9
- Publisher
  乳癌の臨床
- Data Source
  KAKENHI-PROJECT-26290042
[Book] BRCA1/2の基礎とPARP阻害剤2018
- Author(s)
  太田智彦
- Total Pages
  9
- Publisher
  乳癌の臨床
- Data Source
  KAKENHI-PROJECT-16K15712
[Book] BRCA1/2の基礎とPARP阻害剤2018
- Author(s)
  太田智彦
- Total Pages
  9
- Publisher
  乳癌の臨床
- Data Source
  KAKENHI-PROJECT-17H03585
[Book] 臨床医のための乳腺基礎医学「乳癌におけるDNA損傷と修復不全」2018
- Author(s)
  頼勇強, 太田智彦
- Total Pages
  5
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-26290042
[Book] 臨床医のための乳腺基礎医学「乳癌におけるDNA損傷と修復不全」2018
- Author(s)
  頼勇強, 太田智彦.
- Total Pages
  5
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-17H03585
[Book] 遺伝子診断・遺伝カウンセリング. 遺伝性乳癌卵巣癌症候群（HBOC）診療の手引き　2017年版2017
- Author(s)
  櫻井晃洋, 赤木究, 和泉美希子, 太田智彦, 三木義男
- Total Pages
  44
- Publisher
  金原出版
- Data Source
  KAKENHI-PROJECT-17H03585
[Book] 乳癌学－最新の診断と治療－Ⅲ.乳癌の分子生物学と発症機序「DNA修復不全と乳癌」2017
- Author(s)
  太田智彦
- Total Pages
  6
- Publisher
  日本臨牀
- Data Source
  KAKENHI-PROJECT-26290042
[Book] 乳癌学－最新の診断と治療－Ⅲ.乳癌の分子生物学と発症機序「DNA修復不全と乳癌」2017
- Author(s)
  太田智彦
- Total Pages
  6
- Publisher
  日本臨床
- Data Source
  KAKENHI-PROJECT-16K15712
[Book] 乳癌学－最新の診断と治療－　Ⅲ.乳癌の分子生物学と発症機序「DNA修復不全と乳癌2017
- Author(s)
  太田智彦
- Total Pages
  6
- Publisher
  日本臨床
- Data Source
  KAKENHI-PROJECT-17H03585
[Book] 遺伝子診断・遺伝カウンセリング. 遺伝性乳癌卵巣癌症候群（HBOC）診療の手引き　2017年版2017
- Author(s)
  櫻井晃洋, 赤木究, 和泉美希子, 太田智彦, 三木義男
- Total Pages
  44
- Publisher
  金原出版
- Data Source
  KAKENHI-PROJECT-16K15712
[Book] 遺伝子診断・遺伝カウンセリング. 遺伝性乳癌卵巣癌症候群（HBOC）診療の手引き　2017年版2017
- Author(s)
  櫻井晃洋, 赤木究, 和泉美希子, 太田智彦, 三木義男
- Total Pages
  44
- Publisher
  金原出版
- Data Source
  KAKENHI-PROJECT-26290042
[Journal Article] Editorial: Community series in post-translational modifications of proteins in cancer immunity and immunotherapy, volume II2023
- Author(s)
  Nihira Naoe Taira、Ohta Tomohiko、Liu Zichuan、Dai Xiangpeng
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 14 Pages: 01-03
- DOI
  10.3389/fimmu.2023.1289016
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06681, KAKENHI-PROJECT-23K27668
[Journal Article] Potential role of Fbxo22 in resistance to endocrine therapy in breast cancer with invasive lobular carcinoma2023
- Author(s)
  Nakagawa S, Miyashita M, Maeda I, Goda A, Tada H, Amari M, Kojima Y, Tsugawa K, Ohi Y, Sagara Y, Sato M, Ebata A, Shoji NH, Suzuki T, Nakanishi M, Ohta T, Ishida T
- Journal Title
  
  Breast Cancer Res Treat.
  
  Volume: 204 Pages: 453-463
- DOI
  10.21203/rs.3.rs-3375926/v1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27668
[Journal Article] Alteration of Trop-2 expression in breast cancer cells by clinically used therapeutic agents and acquired tamoxifen resistance2022
- Author(s)
  Zhu Jing、Wu Wenwen、Togashi Yukiko、Taira Nihira Naoe、Johmura Yoshikazu、Zhu Dajiang、Nakanishi Makoto、Miyoshi Yasuo、Ohta Tomohiko
- Journal Title
  
  Breast Cancer
  
  Volume: 29 Issue: 6 Pages: 1076-1087
- DOI
  10.1007/s12282-022-01389-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03431, KAKENHI-PROJECT-20H03748, KAKENHI-PROJECT-20J40010
[Journal Article] Lack of impact of the <scp>ALDH2</scp> rs671 variant on breast cancer development in Japanese <scp>BRCA1</scp> /2‐mutation carriers2022
- Author(s)
  Mori Tomoharu、Takata Minoru et al.
- Journal Title
  
  Cancer Medicine
  
  Volume: 12 Issue: 6 Pages: 6594-6602
- DOI
  10.1002/cam4.5430
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21394, KAKENHI-PROJECT-22K19577, KAKENHI-PROJECT-21K15362, KAKENHI-PROJECT-20H03450, KAKENHI-PROJECT-20H03748
[Journal Article] The ZZ domain of HERC2 is a receptor of arginylated substrates2022
- Author(s)
  Tencer AH, Liu J, Zhu J, Burkholder NT, Zhang Y, Wu W, Strahl BD, Ohta T, Kutateladze TG.
- Journal Title
  
  Sci Rep.
  
  Volume: 12 Issue: 1 Pages: 6063-6063
- DOI
  10.1038/s41598-022-10119-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03748
[Journal Article] Molecular targeted drugs resistance impairs double-strand break repair and sensitizes ER-positive breast cancer to PARP inhibitors2021
- Author(s)
  Suzuki Y, Wu W, Ohta T, Hayashi S
- Journal Title
  
  Breast Cancer.
  
  Volume: 29 Issue: 1 Pages: 77-91
- DOI
  10.1007/s12282-021-01282-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03748
[Journal Article] TP53/p53-FBXO22-TFEB controls basal autophagy to govern hormesis2021
- Author(s)
  Suzuki Narumi、Johmura Yoshikazu、Wang Teh-Wei、Migita Toshiro、Wu Wenwen、Noguchi Rei、Yamaguchi Kiyoshi、Furukawa Yoichi、Nakamura Shuhei、Miyoshi Ichiro、Yoshimori Tamotsu、Ohta Tomohiko、Nakanishi Makoto
- Journal Title
  
  Autophagy
  
  Volume: 11 Issue: 11 Pages: 1-18
- DOI
  10.1080/15548627.2021.1897961
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22429, KAKENHI-PROJECT-20K21497, KAKENHI-ORGANIZER-17H06391, KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-19H05740, KAKENHI-PROJECT-20H03748, KAKENHI-PUBLICLY-20H04940, KAKENHI-PROJECT-19H03431, KAKENHI-PROJECT-20J13207, KAKENHI-PROJECT-20K07563
[Journal Article] RNF168 E3 ligase participates in ubiquitin signaling and recruitment of SLX4 during DNA crosslink repair2021
- Author(s)
  Katsuki Yoko、Abe Masako、Park Seon Young、Wu Wenwen、Yabe Hiromasa、Yabe Miharu、van Attikum Haico、Nakada Shinichiro、Ohta Tomohiko、Seidman Michael M.、Kim Yonghwan、Takata Minoru
- Journal Title
  
  Cell Reports
  
  Volume: 37 Issue: 4 Pages: 109879-109879
- DOI
  10.1016/j.celrep.2021.109879
- NAID
  120007165816
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03450, KAKENHI-PROJECT-20H03748, KAKENHI-PROJECT-20K12161, KAKENHI-PROJECT-20K21394
[Journal Article] HERC2 inactivation abrogates nucleolar localization of RecQ helicases BLM and WRN2021
- Author(s)
  Zhu M, Wu W, Togashi Y, Liang W, Miyoshi Y, Ohta T
- Journal Title
  
  Sci Rep.
  
  Volume: 11 Issue: 1 Pages: 360-360
- DOI
  10.1038/s41598-020-79715-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03748
[Journal Article] Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast2021
- Author(s)
  Satoi Nagasawa, Yuta Kuze, Ichiro Maeda, Yasuyuki Kojima, Ai Motoyoshi, Tatsuya Onishi, Hibiki Seino, Ayako Suzuki, Masahide Seki, Eisuke Inoue, Koichiro Tsugawa, Tomohiko Ohta, Yutaka Suzuki, et al.
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1
- DOI
  10.1038/s42003-021-01959-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-20H03748
[Journal Article] FBXO22, an epigenetic multiplayer coordinating senescence, hormone signaling, and metastasis2020
- Author(s)
  Johmura Yoshikazu、Harris Alexander S.、Ohta Tomohiko、Nakanishi Makoto
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 8 Pages: 2718-2725
- DOI
  10.1111/cas.14534
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21497, KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-19H05740, KAKENHI-PROJECT-20H03748
[Journal Article] HERC2 regulates RPA2 by mediating ATR-induced Ser33 phosphorylation and ubiquitin-dependent degradation.2019
- Author(s)
  Lai Y, Zhu M, Wu W, Rokutanda N, Togashi Y, Liang W, Ohta T.
- Journal Title
  
  Sci Rep.
  
  Volume: 9 Issue: 1 Pages: 14257-14257
- DOI
  10.1038/s41598-019-50812-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08676, KAKENHI-PROJECT-17H03585
[Journal Article] Fbxo22-mediated KDM4B degradation determines selective estrogen receptor modulator activity in breast cancer.2018
- Author(s)
  Johmura Y, Maeda I, Suzuki N, Wu W, Goda A,Morita M, Yamaguchi K, Yamamoto M, Nagasawa S, Kojima Y, Tsugawa K, Inoue N, Miyoshi Y, Osako T Akiyama F, Maruyama R, Inoue JI, Fukukawa Y, Ohta T, Nkanishi M.
- Journal Title
  
  J Clin Invest.
  
  Volume: 128 Issue: 12 Pages: 5603-5619
- DOI
  10.1172/jci121679
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08676, KAKENHI-PROJECT-18K15235, KAKENHI-PLANNED-16H06575, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05026, KAKENHI-PROJECT-17H03575, KAKENHI-PROJECT-17H03585, KAKENHI-PROJECT-16H06148, KAKENHI-PROJECT-16K15238, KAKENHI-PROJECT-17K18336, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17H01398, KAKENHI-PROJECT-17K07214
[Journal Article] HERC2 facilitates BLM and WRN helicase complex interaction with RPA to suppress G-quadruplex DNA.2018
- Author(s)
  Wu W, Rokutanda N, Takeuchi J, Lai Y, Maruyama R, Togashi Y, Nishikawa H, Arai N, Miyoshi Y,Suzuki N, Saeki Y, Tanaka K, Ohta T.
- Journal Title
  
  Cancer Res.
  
  Volume: 78 Issue: 22 Pages: 6371-6385
- DOI
  10.1158/0008-5472.can-18-1877
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08676, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PROJECT-18H03993, KAKENHI-PROJECT-17H03585, KAKENHI-PROJECT-17K18336
[Journal Article] Chromatin Regulation by HP1γ Contributes to Survival of 5-Azacytidine-Resistant Cells.2018
- Author(s)
  Imanishi S, Umezu T, Kobayashi C, Ohta T, Ohyashiki K, Ohyashiki JH.
- Journal Title
  
  Front Pharmacol.
  
  Volume: 9 Pages: 1166-1166
- DOI
  10.3389/fphar.2018.01166
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07244, KAKENHI-PROJECT-17H03585, KAKENHI-PROJECT-16K07183, KAKENHI-PROJECT-17K15656
[Journal Article] HP1 regulates the localization of FANCJ at sites of DNA double-strand breaks.2016
- Author(s)
  Wu W, Togashi Y, Johmura Y, Miyoshi Y, Nobuoka S, Nakanishi M, Ohta T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 107 Issue: 10 Pages: 1406-1415
- DOI
  10.1111/cas.13008
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24112005, KAKENHI-PROJECT-16H06148, KAKENHI-PROJECT-26460402, KAKENHI-PROJECT-16K15238, KAKENHI-PROJECT-16K15712, KAKENHI-PROJECT-16K15239, KAKENHI-PROJECT-26290042, KAKENHI-PROJECT-26250027
[Journal Article] 癌の発症と治療におけるユビキチン系の役割2016
- Author(s)
  扇屋りん, 太田智彦
- Journal Title
  
  医学のあゆみ
  
  Volume: 256 Pages: 868-873
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-24112005
[Journal Article] Functional Link between BRCA1 and BAP1 through Histone H2A, Heterochromatin and DNA Damage Response.2016
- Author(s)
  Fukuda T, Tsuruga T, Kuroda T, Nishikawa H, Ohta T.
- Journal Title
  
  Curr Cancer Drug Targets.
  
  Volume: 16(2) Issue: 2 Pages: 101-9
- DOI
  10.2174/1568009615666151030102427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461962, KAKENHI-PLANNED-24112005, KAKENHI-PROJECT-26670730, KAKENHI-PROJECT-26290042
[Journal Article] 癌の発症と治療におけるユビキチン系の役割2016
- Author(s)
  扇屋りん, 太田智彦
- Journal Title
  
  医学のあゆみ
  
  Volume: 256 Pages: 868-873
- Data Source
  KAKENHI-PROJECT-26670730
[Journal Article] 癌の発症と治療におけるユビキチン系の役割2016
- Author(s)
  扇屋りん, 太田智彦
- Journal Title
  
  医学のあゆみ
  
  Volume: 256 Pages: 868-873
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26290042
[Journal Article] Interaction of BARD1 and HP1 Is Required for BRCA1 Retention at Sites of DNA Damage.2015
- Author(s)
  Wu W, Nishikawa H, Fukuda T, Vittal V, Asano M, Miyoshi Y, Klevit RE, Ohta T
- Journal Title
  
  Cancer Res
  
  Volume: 75 Issue: 7 Pages: 1311-1321
- DOI
  10.1158/0008-5472.can-14-2796
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460402, KAKENHI-PLANNED-24112005, KAKENHI-PROJECT-26670730, KAKENHI-PROJECT-25290031, KAKENHI-PROJECT-26290042
[Journal Article] Class I HDAC inhibitors inhibit the retention of BRCA1 and 53BP1 at the site of DNA damage2015
- Author(s)
  Fukuda T,Wu W, Okada M,Maeda I, Kojima Y, Hayami R, Miyoshi Y, Tsugawa K, Ohta T
- Journal Title
  
  Cancer Science
  
  Volume: 106 Issue: 8 Pages: 1050-1056
- DOI
  10.1111/cas.12717
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460402, KAKENHI-PLANNED-24112005, KAKENHI-PUBLICLY-26102741, KAKENHI-PROJECT-26670730, KAKENHI-PROJECT-26290042
[Journal Article] Interaction of BARD1 and HP1 is required for BRCA1 retention at sites of DNA damage.2015
- Author(s)
  Wu W, Nishikawa H, Fukuda T, Vittal V, Asano M, Miyoshi Y, Klevit RE, Ohta T.
- Journal Title
  
  Cancer Res.
  
  Volume: 75 Pages: 1311-1321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670730
[Journal Article] Ubiquitin acetylation inhibits polyubiquitin chain elongation.2015
- Author(s)
  Ohtake F, Saeki Y, Sakamoto K, Ohtake K, Nishikawa H, Tsuchiya H, Ohta T, Tanaka K, Kanno J.
- Journal Title
  
  EMBO Rep.
  
  Volume: 16 Issue: 2 Pages: 192-201
- DOI
  10.15252/embr.201439152
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24112005, KAKENHI-PLANNED-24112008, KAKENHI-PROJECT-26290042, KAKENHI-PROJECT-26291035, KAKENHI-PROJECT-26670730, KAKENHI-PROJECT-26870853, KAKENHI-PLANNED-24112004, KAKENHI-PROJECT-26000014
[Journal Article] Interaction of BARD1 and HP1 is required for BRCA1 retention at sites of DNA damage.2015
- Author(s)
  Wu W, Nishikawa H, Fukuda T, Vittal V, Asano M, Miyoshi Y, Klevit RE, Ohta T.
- Journal Title
  
  Cancer Res.
  
  Volume: 75 Pages: 1311-1321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26290042
[Journal Article] LSD1 Overexpression Is Associated with Poor Prognosis in Basal-Like Breast Cancer, and Sensitivity to PARP Inhibition.2015
- Author(s)
  Nagasawa S, Sedukhina AS, Nakagawa Y, Maeda I, Kubota M, Ohnuma S, Tsugawa K, Ohta T, Roche-Molina M, Bernal JA, Narváez AJ, Jeyasekharan AD, Sato K.
- Journal Title
  
  PLoS One.
  
  Volume: 10 Issue: 2 Pages: e0118002-e0118002
- DOI
  10.1371/journal.pone.0118002
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24112005, KAKENHI-PROJECT-26290042, KAKENHI-PROJECT-26670730
[Journal Article] NF-kB signaling mediates acquired resistance after PARP inhibition.2015
- Author(s)
  Nakagawa Y, Sedukhina AS, Okamoto N, Nagasawa S, Suzuki N, Ohta T, Hattori H, Roche-Molina M, Narváez AJ, Jeyasekharan AD, Bernal JA, Sato K.
- Journal Title
  
  Oncotarget.
  
  Volume: 6 Pages: 3825-3539
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24112005
[Journal Article] MED12 exon 2 mutations in phyllodes tumors of the breast2015
- Author(s)
  Nagasawa S, Maeda I, Fukuda T, Wu W, Hayami R, Kojima Y, Tsugawa KI, Ohta T
- Journal Title
  
  Cancer Med
  
  Volume: Epub ahead of print Issue: 7 Pages: 1-5
- DOI
  10.1002/cam4.462
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460402, KAKENHI-PLANNED-24112005, KAKENHI-PROJECT-26670730, KAKENHI-PROJECT-26290042
[Journal Article] Liganded ERα stimulates the E3 ubiquitin ligase activity of UBE3C to facilitate cell proliferation2015
- Author(s)
  Okada M, Ohtake F, Nishikawa H, Wu W, Saeki Y, Takana K, Ohta T
- Journal Title
  
  Molecular Endocrinology
  
  Volume: 29 Issue: 11 Pages: 1646-1657
- DOI
  10.1210/me.2015-1125
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460402, KAKENHI-PLANNED-24112005, KAKENHI-PLANNED-24112008, KAKENHI-PUBLICLY-26102741, KAKENHI-PROJECT-26670730, KAKENHI-PROJECT-26290042, KAKENHI-PROJECT-26000014
[Journal Article] NF-kB signaling mediates acquired resistance after PARP inhibition.2015
- Author(s)
  Nakagawa Y, Sedukhina AS, Okamoto N, Nagasawa S, Suzuki N, Ohta T, Hattori H, Roche-Molina M, Narváez AJ, Jeyasekharan AD, Bernal JA, Sato K.
- Journal Title
  
  Oncotarget.
  
  Volume: 6 Pages: 3825-3839
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670730
[Journal Article] The BARD1/HP1 interaction: another clue about heterochromatin involvement in homologous recombination2015
- Author(s)
  Fukuda T, Tsuruga T, Kuroda T, Takeuchi J, Wu W, Ohta T
- Journal Title
  
  Molecular & Cellular Oncology
  
  Volume: aEpub ahead of print Issue: 2 Pages: 1-3
- DOI
  10.1080/23723556.2015.1030535
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460402, KAKENHI-PLANNED-24112005, KAKENHI-PROJECT-26670730, KAKENHI-PROJECT-26290042
[Journal Article] Interaction of BARD1 and HP1 is required for BRCA1 retention at sites of DNA damage.2015
- Author(s)
  Wu W, Nishikawa H, Fukuda T, Vittal V, Asano M, Miyoshi Y, Klevit RE, Ohta T.
- Journal Title
  
  Cancer Res.
  
  Volume: 75 Pages: 1311-1321
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24112005
[Journal Article] NF-kB signaling mediates acquired resistance after PARP inhibition.2015
- Author(s)
  Nakagawa Y, Sedukhina AS, Okamoto N, Nagasawa S, Suzuki N, Ohta T, Hattori H, Roche-Molina M, Narváez AJ, Jeyasekharan AD, Bernal JA, Sato K.
- Journal Title
  
  Oncotarget.
  
  Volume: 6 Pages: 3825-3539
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26290042
[Journal Article] Aberrant DNA methylation status of DNA repair genes in breast cancer treated with neoadjuvant chemotherapy2013
- Author(s)
  Watanabe Y, Maeda I, Oikawa R, Wu W, Tsuchiya K, Miyoshi Y, Itoh F, Tsugawa K, Ohta T
- Journal Title
  
  Genes to Cells
  
  Volume: 18(12) Issue: 12 Pages: 1120-1130
- DOI
  10.1111/gtc.12100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300358, KAKENHI-PROJECT-23590348, KAKENHI-PLANNED-24112005
[Journal Article] A DNA-Damage Selective Role for BRCA1 E3 Ligase in Claspin Ubiquitylation, CHK1 Activation, and DNA Repair2012
- Author(s)
  Sato K, Sundaramoorthy E, Rajendra E, Hattori H, Jeyasekharan AD, Ayoub N, Schiess R, Aebersold R, Nishikawa H, Sedukhina AS, Wada H, Ohta T, Venkitaraman AR
- Journal Title
  
  Curr Biol
  
  Volume: 22 Issue: 18 Pages: 1659-66
- DOI
  10.1016/j.cub.2012.07.034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300358, KAKENHI-PROJECT-24591568, KAKENHI-PLANNED-24112005
[Journal Article] DNA相同組換え修復と乳癌2012
- Author(s)
  太田智彦
- Journal Title
  
  Medical Science Digest
  
  Volume: 38 Pages: 637-40
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23131514
[Journal Article] 乳癌治療におけるユビキチン修飾2012
- Author(s)
  佐藤工, 太田智彦
- Journal Title
  
  医学のあゆみ
  
  Volume: 243(6) Pages: 520-524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300358
[Journal Article] BRCA1とDNA損傷応答2012
- Author(s)
  セドキーナアンナ, 福田貴代, 太田智彦
- Journal Title
  
  生化学
  
  Volume: 84(7) Pages: 637-640
- NAID
  10030966547
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300358
[Journal Article] DNA相同組換え修復と乳癌2012
- Author(s)
  太田智彦
- Journal Title
  
  Medical Science Digest
  
  Volume: 38 Pages: 637-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300358
[Journal Article] DNA 相同組換え修復と乳癌2012
- Author(s)
  太田智彦, 西川裕之
- Journal Title
  
  Medical Science Digest
  
  Volume: 38(1) Pages: 637-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300358
[Journal Article] 乳癌-基礎と臨床の最新研究動向-」III乳癌の分子生物学と発癌機序1. 分子生物学 (2)癌遺伝子と癌抑制遺伝子2012
- Author(s)
  福田貴代, セドキーナアンナ, 太田智彦
- Journal Title
  
  日本臨牀 : 増刊号「乳癌」
  
  Volume: 9 Pages: 66-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300358
[Journal Article] The BRCA1 ubiquitin ligase and homologous recombination repair2011
- Author(s)
  Ohta T
- Journal Title
  
  FEBS Lett
  
  Volume: 585 Issue: 18 Pages: 2836-44
- DOI
  10.1016/j.febslet.2011.05.005
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23131514, KAKENHI-PROJECT-23300358
[Journal Article] HERC2 Interacts with Claspin and regulates DNA origin firingandr eplication fork progression2011
- Author(s)
  Izawa N, Wu W, Sato K, Nishikawa H, Kato A, Boku N, Itoh F, Ohta T
- Journal Title
  
  Cancer Research
  
  Volume: Volume 71 Issue: 17 Pages: 5621-5625
- DOI
  10.1158/0008-5472.can-11-0385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710053, KAKENHI-PUBLICLY-23131514, KAKENHI-PROJECT-23300358, KAKENHI-PROJECT-23590348
[Journal Article] DNA損傷応答と乳癌の薬剤感受性2010
- Author(s)
  太田智彦,小泉宏隆,呉文文
- Journal Title
  
  乳癌の臨床2010年(篠原出版新社) 第25巻、第6号
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591557
[Journal Article] BRCA遺伝子異常と標的治療2010
- Author(s)
  太田智彦
- Journal Title
  
  がん分子標的治療
  
  Volume: 8 Pages: 46-52
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025032
[Journal Article] 「乳がん」、遺伝子診療学(第2版)-遺伝子診断の進歩とゲノム治療の展望-2010
- Author(s)
  太田智彦
- Journal Title
  
  日本臨床 984巻、8号
  
  Pages: 438-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591557
[Journal Article] BRCA遺伝子異常と標的治療2010
- Author(s)
  太田智彦
- Journal Title
  
  がん分子標的治療 (In press)
- Data Source
  KAKENHI-PROJECT-20058036
[Journal Article] がんのゲノム解析と診療への応用 a)乳がん2010
- Author(s)
  太田智彦
- Journal Title
  
  日本臨牀 (In press)
- Data Source
  KAKENHI-PROJECT-20591557
[Journal Article] Recruitment of phosphorylated NPM1 to sites of DNA damage through RNF8-dependent ubiquitin conjugates.2010
- Author(s)
  Koike A, Nishikawa H, Wu W, Okada Y, Venkitaraman AR, Ohta T.
- Journal Title
  
  Cancer Res. 70(17)
  
  Pages: 6746-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591557
[Journal Article] Prediction of breast cancer sensitivity to neoadjuvant chemotherapy based on status of DNA damage repair proteins.2010
- Author(s)
  Asakawa H, Koizumi H, Koike A, Takahashi M, Wu W, Iwase H, Fukuda M, Ohta T.
- Journal Title
  
  Breast Cancer Res. 12(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591557
[Journal Article] がんのゲノム解析と診療への応用a)乳がん2010
- Author(s)
  太田智彦
- Journal Title
  
  日本臨林 (In press)
- Data Source
  KAKENHI-PROJECT-20058036
[Journal Article] BRCA遺伝子異常と標的治療2010
- Author(s)
  太田智彦
- Journal Title
  
  がん分子標的治療 (In press)
- Data Source
  KAKENHI-PROJECT-20591557
[Journal Article] Clinicopathological analyses of triple negative breast cancer using surveillance data from the Registration Committee of the Japanese Breast Cancer Society.2010
- Author(s)
  Iwase H, Kurebayashi J, Tsuda H, Ohta T, Kurosumi M, Miyamoto K, Yamamoto Y, Iwase T
- Journal Title
  
  Breast Cancer. 17(2)
  
  Pages: 118-24
- NAID
  10027255494
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591557
[Journal Article] がんのゲノム解析と診療への応用a)乳がん2010
- Author(s)
  太田智彦
- Journal Title
  
  日本臨牀 (In press)
- Data Source
  KAKENHI-PUBLICLY-21025032
[Journal Article] 乳がん2010
- Author(s)
  太田智彦
- Journal Title
  
  日本臨牀遺伝子診療学(第2版)
  
  Volume: 984 Pages: 438-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591557
[Journal Article] Venkitaraman AR. A mitotic role for the DNA damage-responsive CHK2 kinase.2010
- Author(s)
  Sato K, Ohta T
- Journal Title
  
  Nat Cell Biol. 12(5)
  
  Pages: 424-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591557
[Journal Article] HERC2 is an E3 ligase that targets BRCA1 for degradation.2010
- Author(s)
  Wu W, Sato K, Koike A, Nishikawa H, Koizumi H, Venkitaraman AR, Ohta T.
- Journal Title
  
  Cancer Res. 70(15)
  
  Pages: 6384-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591557
[Journal Article] BRCA遺伝子異常と標的治療2010
- Author(s)
  太田智彦
- Journal Title
  
  がん分子標的治療(メディカルレビュー社) Vol.8 No.2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591557
[Journal Article] 乳がん2010
- Author(s)
  太田智彦
- Journal Title
  
  日本臨林遺伝子診療学(第2版)
  
  Volume: 984 Pages: 438-43
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025032
[Journal Article] Hoxb4 transduction down-regulates Geminin protein, providing hematopoietic stem and progenitor cells with proliferation potential.2010
- Author(s)
  Ohno Y, Yasunaga S, Ohtsubo M, Mori S, Tsumura M, Okada S, Ohta T, Ohtani K, Kobayashi M, Takihara Y
- Journal Title
  
  Proc Natl Acad Sci U S A. 107(50)
  
  Pages: 21529-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591557
[Journal Article] DNA損傷応答と乳癌の薬剤感受性2010
- Author(s)
  太田智彦
- Journal Title
  
  乳癌の臨床
  
  Volume: 25 Pages: 609-15
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025032
[Journal Article] DNA損傷応答と乳癌の薬剤感受性2010
- Author(s)
  太田智彦
- Journal Title
  
  乳癌の臨床
  
  Volume: 25 Pages: 609-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591557
[Journal Article] BRCA遺伝子異常と標的治療2010
- Author(s)
  太田智彦
- Journal Title
  
  がん分子標的治療
  
  Volume: 8 Pages: 46-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591557
[Journal Article] BRCA遺伝子異常と標的治療2010
- Author(s)
  太田智彦
- Journal Title
  
  がん分子標的治療 (In press)
- Data Source
  KAKENHI-PUBLICLY-21025032
[Journal Article] Perturbation of DNA repair pathways by proteasome inhibitors corresponds to enhanced chemosensitivity of cells to DNA damage-inducing agents.2009
- Author(s)
  Takeshita T, Wu W, Koike A, Fukuda M, Ohta T.
- Journal Title
  
  Cancer Chemother. Pharmacol. 64
  
  Pages: 1039-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591557
[Journal Article] Contemplating chemosensitivity of basal-like breast cancer based on BRCA1 dysfunction.2009
- Author(s)
  Tomohiko Ohta
- Journal Title
  
  Breast Cancer 16
  
  Pages: 268-74
- NAID
  10027254733
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025032
[Journal Article] BAP1 interferes with BRCA1/BARD1 RING heterodimer activity.2009
- Author(s)
  Nishikawa H, Wu W, Koike A, Kojima R, Gomi H, Fukuda M, Ohta T.
- Journal Title
  
  Cancer Res. 69
  
  Pages: 111-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591557
[Journal Article] Contemplating chemosensitivity of basal-like breast cancer based on BRCA1 dysfunction.2009
- Author(s)
  Tomohiko Ohta
- Journal Title
  
  Breast Cance 16
  
  Pages: 268-74
- NAID
  10027254733
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20058036
[Journal Article] Contemplating chemosensitivity of basal-like breast cancer based on BRCA1 dysfunction.2009
- Author(s)
  Tomohiko Ohta
- Journal Title
  
  Breast Cancer 16
  
  Pages: 268-74
- NAID
  10027254733
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591557
[Journal Article] Contemplating chemosensitivity of basal-like breast cancer based on BRCA1 dysfunction2009
- Author(s)
  Tomohiko Ohta
- Journal Title
  
  Breast Cancer (In press)
- NAID
  10027254733
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20058036
[Journal Article] Contemplating chemosensitivity of basal-like breast cancer based on BRCA1 dysfunction.2009
- Author(s)
  Ohta T, Wu W, Koike A, Asakawa H, Koizumi H, Fukuda M
- Journal Title
  
  Breast Cancer. 16(4)
  
  Pages: 268-74
- NAID
  10027254733
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591557
[Journal Article] Contemplating chemosensitivity of basal-like breast cancer based on BRCAl dysfunction2009
- Author(s)
  Tomohiko Ohta
- Journal Title
  
  Breast Cancer (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591557
[Journal Article] The ubiquitin E3 ligase activity of BRCA1 and its biological functions.2008
- Author(s)
  Wu W, Koike A, Takeshita T, Ohta T.
- Journal Title
  
  Cell Div. Jan 7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591446
[Journal Article] Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis.2008
- Author(s)
  Shimo A, Tanikawa C, Nishidate T, Lin ML, Matsuda K, Park JH, Ueki T, Ohta T, Hirata K, Fukuda M, Nakamura Y, Katagiri T
- Journal Title
  
  Cancer Sci. 99
  
  Pages: 62-70
- NAID
  10024000927
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591557
[Journal Article] Contemplating chemosensitivity of basal-like breast cancer based on BRCAI dysfunction2008
- Author(s)
  Tomohiko Ohta
- Journal Title
  
  Breast Cancer (In press)(Open amass)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19044042
[Journal Article] Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis.2008
- Author(s)
  Shimo A, Tanikawa C, Nishidate T, Lin ML, Matsuda K, Park JH, Ueki T, Ohta T, Hirata K, Fukuda M, Nakamura Y, Katagiri T.
- Journal Title
  
  Cancer Sci. 99(1)
  
  Pages: 62-70
- NAID
  10024000927
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591486
[Journal Article] The ubiquitin E3 ligase activity of BRCA1 and its biological functions.2008
- Author(s)
  Wu W, Koike A, Takeshita T, Ohta T.
- Journal Title
  
  Cell Div. 3:1
  
  Pages: 1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591557
[Journal Article] Modification of the hepatic mitochondrial proteome in response to ischemic preconditioning following ischemia-reperfusion injury of the rat liver.2008
- Author(s)
  Oshima R, Nakano H, Katayama M, Sakurai J, Wu W, Koizumi S, Asano T, Watanabe T, Asakura T, Ohta T, Otsubo T
- Journal Title
  
  Eur Surg Res. 40
  
  Pages: 247-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591557
[Journal Article] The ubiquitin E3 ligase activity of BRCA1 and its biological functions.2008
- Author(s)
  Wu W, Koike A, Takeshita T, Ohta T.
- Journal Title
  
  Cell Div. Jan 7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591486
[Journal Article] Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis.2008
- Author(s)
  Shimo A, Tanikawa C, Nishidate T, Lin ML, Matsuda K, Park JH, Ueki T, Ohta T, Hirata K, Fukuda M, Nakamura Y, Katagiri T.
- Journal Title
  
  Cancer Sci. 99(1)
  
  Pages: 62-70
- NAID
  10024000927
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591446
[Journal Article] The UPS : A promising target for breast cancer treatment.2008
- Author(s)
  Sato K, Rajendra E, Ohta T.
- Journal Title
  
  BMC Biochem. 9(suppl 1):S2
  
  Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591557
[Journal Article] 「研究成果報告書概要(欧文)」より2007
- Author(s)
  Yamasaki S, Yagishita N, Sasaki T, Nakazawa M, Kato Y, Yamadera T, Bae E, Toriyama S, Ikeda R, Zhang L, Fujitani K, Yoo E, Tsuchimochi K, Ohta T, Araya N, Fujita H, Aratani S, Eguchi K, Komiya S, Maruyama I, Higashi N, Sato M, Senoo H, Ochi T, Yokoyama S, Amano T, Kim J, Gay S, Fukamizu A, Nishioka K, Tanaka K, Nakajima T.
- Journal Title
  
  EMBO J. 26
  
  Pages: 113-22
- Data Source
  KAKENHI-PROJECT-18591446
[Journal Article] Predictive markers in breast cancer treatment-focusing on a recent topicbasal-like breast cancer2007
- Author(s)
  Koike A, Ohta T.
- Journal Title
  
  Nippon Rinsho.(Suppl 6) 65
  
  Pages: 285-90
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591486
[Journal Article] BRCA1 ubiquitinates RPB8 in response to DNA damage.2007
- Author(s)
  Wu W, Nishikawa H, Hayami R, Sato K, Honda A, Aratani S, Nakajima T, Fukuda M, Ohta T.
- Journal Title
  
  Cancer Res. 67(3)
  
  Pages: 951-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591486
[Journal Article] BECA1 ubiquitinates RPB8 in response to DNA damage.2007
- Author(s)
  Ohta T, et al.
- Journal Title
  
  Cancer Res. 67(3)
- Data Source
  KAKENHI-PROJECT-18591486
[Journal Article] Predictive markers in breast cancer treatment-focusing on a recent topic "basal-like breast cancer"2007
- Author(s)
  Ohta T, et. al.
- Journal Title
  
  Nippon Rinsho 65Suppl6
  
  Pages: 285-90
- NAID
  40015531685
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591486
[Journal Article] BRCA1 ubiquitinates RPB8 in response to DNA damage.2007
- Author(s)
  Wu W, Nishikawa H, Hayami R, Sato K, Honda A, Aratani S, Nakajima T, Fukuda M, Ohta T.
- Journal Title
  
  Cancer Res. 67(3)
  
  Pages: 951-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591446
[Journal Article] Modification of the Hepatic Mitochondrial Proteome in Response to Ischemic Preconditioning following Ischemia-Reperfusion Injury of the Rat Liver.2007
- Author(s)
  Oshima R, Nakano H, Katayama M, Sakurai J, Wu W, Koizumi S, Asano T, Watanabe T, Asakura T, Ohta T, Otsubo T.
- Journal Title
  
  Eur Surg Res. 40(3)
  
  Pages: 247-255
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591446
[Journal Article] Putative tumor suppressor EDD interacts with and up-regulates APC.2007
- Author(s)
  Ohshima R, Ohta T, Wu W, Koike A, Iwatani T, Henderson M, Watts CK, Otsubo T.
- Journal Title
  
  Genes Cells. 12(12)
  
  Pages: 1339-45
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591446
[Journal Article] Predictive markers in breast cancer treatment-focusing on a recent topicbasal-like breast cancer2007
- Author(s)
  Koike A, Ohta T.
- Journal Title
  
  Nippon Rinsho.(Suppl 6) 65
  
  Pages: 285-90
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591446
[Journal Article] Putative tumor suppressor EDD interacts with and up-regulates APC.2007
- Author(s)
  Ohshima R, Ohta T, Wu W, Koike A, Iwatani T, Henderson M, Watts CK, Otsubo T.
- Journal Title
  
  Genes Cells. 12(12)
  
  Pages: 1339-45
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591486
[Journal Article] Elevated expression of PRC1,involved in the growth of breast cancer cells.2007
- Author(s)
  Ohta T, er al
- Journal Title
  
  Cancer Sci. 98
  
  Pages: 174-81
- Data Source
  KAKENHI-PROJECT-18591486
[Journal Article] Putative tumor suppressor EDD interacts with and up-regulates APC.2007
- Author(s)
  Ohta, T, et. al.
- Journal Title
  
  Genes Cells 12
  
  Pages: 1339-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591486
[Journal Article] Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase'Synoviolin'.2007
- Author(s)
  Yamasaki S, Yagishita N, Sasaki T, Nakazawa M, Kato Y, Yamadera T, Bae E, Toriyama S, Ikeda R, Zhang L, Fujitani K, Yoo E, Tsuchimochi K, Ohta T, Araya N, Fujita H, Aratani S, Eguchi K, Komiya S, Maruyama I, Higashi N, Sato M, Senoo H, Ochi T, Yokoyama S, Amano T, Kim J, Gay S, Fukamizu A, Nishioka K, Tanaka K, Nakajima T.
- Journal Title
  
  EMBO J. 26
  
  Pages: 113-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591486
[Journal Article] Modification of the Hepatic Mitochondrial Proteome in Response to Ischemic Preconditioning following Ischemia-Reperfusion Injury of the Rat Liver.2007
- Author(s)
  Oshima R, Nakano H, Katayama M, Sakurai J, Wu W, Koizumi S, Asano T, Watanabe T, Asakura T, Ohta T, Otsubo T.
- Journal Title
  
  Eur Surg Res. 40(3)
  
  Pages: 247-255
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591486
[Journal Article] Breast and ovarian cancer susceptibility product BRCA12007
- Author(s)
  Ohta T.
- Journal Title
  
  Protein Nucleic Acid and Enzyme (PNE) 51
  
  Pages: 1395-1400
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591486
[Journal Article] Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'Synoviolin'.2007
- Author(s)
  Ohta T, er al
- Journal Title
  
  EMBO J. 26
  
  Pages: 113-22
- Data Source
  KAKENHI-PROJECT-18591486
[Journal Article] Modification of the Hepatic Mitochondrial Proteome in Response to Ischemic Preconditioning following Ischemia-Reperfusion Injury of the Rat Liver.2007
- Author(s)
  Ohta T, et. al.
- Journal Title
  
  Eur Surg Res 40(3)
  
  Pages: 247-255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591486
[Journal Article] Elevated expression of PRC1, involved in the growth of breast cancer ells.2007
- Author(s)
  Shimo A, Nishidate T, Ohta T, Fukuda M, Nakamura Y, Katagiri T.
- Journal Title
  
  Cancer Sci. 98
  
  Pages: 174-81
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591486
[Journal Article] Elevated expression of PRC1, involved in the growth of breast cancer cells.2007
- Author(s)
  Shimo A, Nishidate T, Ohta T, Fukuda M, Nakamura Y, Katagiri T.
- Journal Title
  
  Cancer Sci. 98
  
  Pages: 174-81
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591446
[Journal Article] 乳癌および卵巣癌抑制遺伝子BRCA12006
- Author(s)
  太田智彦, ほか
- Journal Title
  
  PNE : 蛋白核酸酵素 51
  
  Pages: 1395-1400
- Data Source
  KAKENHI-PROJECT-18591486
[Journal Article] Breast and ovarian cancer susceptibility product BRCA1.2006
- Author(s)
  Ohta T.
- Journal Title
  
  Protein Nucleic Acid and Enzyme(PNE) 51
  
  Pages: 1395-1400
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591446
[Journal Article] Breast and ovarian cancer susceptibility product BRCA1.2006
- Author(s)
  Ohta T.
- Journal Title
  
  Protein Nucleic Acid and Enzyme(PNE) 51
  
  Pages: 1395-1400
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591486
[Journal Article] 乳癌および卵巣癌抑制遺伝子BRCA12006
- Author(s)
  太田智彦
- Journal Title
  
  PNE:蛋白核酸酵素 51
  
  Pages: 1395-1400
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591446
[Journal Article] 乳癌および卵巣癌抑制遺伝子BRCA12006
- Author(s)
  太田智彦
- Journal Title
  
  PNE : 蛋白核酸酵素 51(10 suppl)
  
  Pages: 1395-1400
- Data Source
  KAKENHI-PROJECT-18591446
[Journal Article] A truncated splice variant of human BARD1 that lacks the RING finger and ankyrin repeats.2006
- Author(s)
  Tsuzuki M, Wu W, Nishikawa H, Hayami R, Oyake D, Yabuki Y, Fukuda M, Ohta T.
- Journal Title
  
  Cancer Lett. 233(1)
  
  Pages: 108-116
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591280
[Journal Article] A FancD2-monoubiquitin fusion reveals hidden functions of Fanconi anemia core complex in DNA repair.2005
- Author(s)
  Matsushita N, Kitao H, Ishiai M, Nagashima N, Hirano S, Okawa K, Ohta T, Yu DS, McHugh PJ, Hickson ID, Venkitaraman AR, Kurumizaka H, Takata M.
- Journal Title
  
  Mol Cell. 19(6)
  
  Pages: 841-847
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591280
[Journal Article] Down-regulation of BRCA1-BARD1 ubiquitin ligase by CDK2.2005
- Author(s)
  Hayami R, Sato K, Wu W, Nishikawa T, Hiroi J, Ohtani-Kaneko R, Fukuda M, Ohta T.
- Journal Title
  
  Cancer Res. 65(1)
  
  Pages: 6-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591280
[Journal Article] 乳がん抑制遺伝子BRCA12004
- Author(s)
  太田智彦
- Journal Title
  
  現代医療 36(4)
  
  Pages: 167-172
- Data Source
  KAKENHI-PROJECT-16026243
[Journal Article] BRCA1ユビキチンリガーゼと乳癌2004
- Author(s)
  太田智彦
- Journal Title
  
  医学のあゆみ 211(1)
  
  Pages: 49-53
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591280
[Journal Article] Breast tumor suppressor BRCA12004
- Author(s)
  Ohta T, Hayami R, Wu W, Fukuda M.
- Journal Title
  
  New Horizon Med. (Japanese) 36(4)
  
  Pages: 167-173
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591280
[Journal Article] 乳がん抑制遺伝子BRCA12004
- Author(s)
  太田智彦
- Journal Title
  
  現代医療 36(4)
  
  Pages: 167-172
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591280
[Journal Article] Nucleophosmin/B23 is a candidate substrate for the BRCA1-BARD1 ubiquitin ligase.2004
- Author(s)
  Sato K, Hayami R, Wu W, Nishikawa T, Nishikawa H, Okuda Y, Ogata H, Fukuda M, Ohta T.
- Journal Title
  
  J.Biol.Chem. 279(30)
  
  Pages: 30919-30922
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591280
[Journal Article] BRCA1ユビキチンリガーゼと乳癌2004
- Author(s)
  太田智彦
- Journal Title
  
  医学のあゆみ 211(1)
  
  Pages: 49-53
- Data Source
  KAKENHI-PROJECT-16026243
[Journal Article] BRCA1 ubiquitin ligase and breast cancer2004
- Author(s)
  Ohta T, Fukuda M.
- Journal Title
  
  J.Clin Exp.Med. (Japanese) 211(1)
  
  Pages: 49-53
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591280
[Journal Article] Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage.2004
- Author(s)
  Hu J, McCall CM, Ohta T, Xiong Y.
- Journal Title
  
  Nat Cell Biol. 6(10)
  
  Pages: 1003-1009
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591280
[Patent] 癌の抑制方法2007
- Inventor(s)
  太田智彦
- Industrial Property Rights Holder
  聖マリアンナ医科大学・太田智彦
- Acquisition Date
  2007-06-21
- Overseas
- Data Source
  KAKENHI-PROJECT-19044042
[Patent] 癌の抑制方法2007
- Inventor(s)
  太田智彦
- Industrial Property Rights Holder
  聖マリアンナ医科大学・太田智彦
- Acquisition Date
  2007-06-21
- Overseas
- Data Source
  KAKENHI-PROJECT-18591446
[Patent] 癌の抑制方法2007
- Inventor(s)
  太田智彦
- Industrial Property Rights Holder
  聖マリアンナ医科大学・太田智彦
- Acquisition Date
  2007-06-21
- Description
  「研究成果報告書概要(和文)」より
- Overseas
- Data Source
  KAKENHI-PROJECT-18591446
[Presentation] Does Trop-2 expression really not matter for the sensitivity to sacituzumab govitecan?2023
- Author(s)
  Tomohiko Ohta
- Organizer
  Best of San Antonio Breast Cancer Symposium (SABCS) 2022 in Kyoto
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03748
[Presentation] BRCA1とヒストン修飾を介したDNA相同組換え修復2023
- Author(s)
  太田智彦
- Organizer
  第3回JOHBOC学術総会
- Data Source
  KAKENHI-PROJECT-23K27668
[Presentation] 乳がんの臨床を左右する新規エピジェネティックメカニズム2021
- Author(s)
  太田智彦
- Organizer
  第29回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03748
[Presentation] BRCA1 N末端の変異とPARP阻害剤感受性: E3リガーゼ活性についての再考2021
- Author(s)
  太田智彦
- Organizer
  第18回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03748
[Presentation] ER陽性乳癌細胞における、薬剤耐性獲得に伴うDNA修復機構異常とPARP阻害薬感受性2021
- Author(s)
  鈴木友菜, 豊澤大地, 呉文文, 太田智彦, 林慎一
- Organizer
  第29回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03748
[Presentation] DNA修復脆弱性を標的としたがん治療2020
- Author(s)
  太田智彦
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03748
[Presentation] エストロゲン受容体の発現を制御するFbxo22は浸潤性小葉癌の予後因子となりうるか2020
- Author(s)
  中川紗紀, 宮下穣, 江幡明子, 佐藤章子, 原田成美, 濱中洋平, 甘利正和, 平川久, 大井恭代, 太田智彦, 多田寛, 石田孝宣
- Organizer
  第28回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03748
[Presentation] CDK4/6阻害薬耐性細胞はDNA修復機構に異常をきたしPARP阻害薬に反応する2020
- Author(s)
  鈴木友菜, 豊澤大地, 呉文文, 丹羽俊文, 太田智彦, 林慎一
- Organizer
  第28回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03748
[Presentation] PARP阻害剤耐性獲得に対する治療戦略2019
- Author(s)
  太田智彦, 朱明章, 呉文文
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H03585
[Presentation] HERC2 ubiquitinates RPA2 in ATR dependent manner and promotes RPA to suppress G-quadruplex DNA.2019
- Author(s)
  Yongqiang Lai, Mingzhang Zhu, Wenwen Wu, Yukiko Togashi, Tomohiko Ohta.
- Organizer
  11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03585
[Presentation] SERM感受性決定因子Fbxo22によるLuminal乳がん高リスク群の同定2019
- Author(s)
  太田智彦
- Organizer
  第27回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H03585
[Presentation] PARP 阻害剤耐性とその克服戦略2019
- Author(s)
  太田智彦
- Organizer
  第17回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-17H03585
[Presentation] HERC2はグアニン四重鎖（G4）の主要な制御因子としてG4安定化剤の感受性を左右する.2018
- Author(s)
  呉文文, 竹内淳, 頼勇強, 三好康雄, 鈴木直, 佐伯泰, 田中啓二, 朱明章, 太田智彦.
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H03585
[Presentation] HERC2 promotes BLM and WRN functions to suppress G-quadruplex DNA.2018
- Author(s)
  Tomohiko Ohta.
- Organizer
  EMBO Meeting Cellular signalling and cancer therapy 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03585
[Presentation] Resistance of Fbxo22 knockout cancer cells to poly(ADP-ribose)polymerase(PARP)inhibitor.2017
- Author(s)
  頼勇強, 呉文文, 梁偉新, 太田智彦
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15712
[Presentation] 乳癌におけるDNA損傷修復不全とPARP阻害剤感受性2017
- Author(s)
  太田智彦
- Organizer
  第25回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15712
[Presentation] Resistance of Fbxo22 knockout cancer cells to poly(ADP-ribose)polymerase(PARP)inhibitor.2017
- Author(s)
  頼勇強, 呉文文, 梁偉新, 太田智彦
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H03585
[Presentation] Resistance of Fbxo22 knockout cancer cells to poly(ADP-ribose)polymerase(PARP)inhibitor.2017
- Author(s)
  頼勇強, 呉文文, 梁偉新, 太田智彦
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-26290042
[Presentation] A novel role of HERC2 in maintaining chromosomal stability.2017
- Author(s)
  Tomohiko Ohta
- Organizer
  6th US-Japan DNA Repair Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15712
[Presentation] A novel role of HERC2 in maintaining chromosomal stability.2017
- Author(s)
  Tomohiko Ohta
- Organizer
  6th US-Japan DNA Repair Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03585
[Presentation] 乳癌におけるDNA損傷修復不全とPARP阻害剤感受性2017
- Author(s)
  太田智彦
- Organizer
  第25回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H03585
[Presentation] 乳癌におけるDNA損傷修復不全とPARP阻害剤感受性2017
- Author(s)
  太田智彦
- Organizer
  第25回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-26290042
[Presentation] A novel role of HERC2 in maintaining chromosomal stability.2017
- Author(s)
  Tomohiko Ohta
- Organizer
  6th US-Japan DNA Repair Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290042
[Presentation] DNA損傷修復機構に関与するユビキチンE3リガーセの検討2016
- Author(s)
  敦賀智子, 岡田麻衣子, 黒田貴子, 宇井彩子, 太田智彦
- Organizer
  第24回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-26290042
[Presentation] TripleNegative型乳癌（Basal型）においてLSD1蛋白の過剰発現は予後不良因子である2016
- Author(s)
  永澤慧, 前田一郎, 太田智彦, 津川浩一郎
- Organizer
  第24回日本乳癌学会学術総会
- Place of Presentation
  東京ビックサイト（東京都江東区）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-16K15712
[Presentation] TripleNegative型乳癌（Basal型）においてLSD1蛋白の過剰発現は予後不良因子である2016
- Author(s)
  永澤慧, 前田一郎, 太田智彦, 津川浩一郎
- Organizer
  第24回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-26290042
[Presentation] ドキシサイクリン誘導性BRCA1欠損ERα陽性細胞を用いた染色体不安定化機構の解析2016
- Author(s)
  黒田貴子, 岡田麻衣子, 敦賀智子, 太田智彦, 津川浩一郎
- Organizer
  第24回日本乳癌学会学術総会
- Place of Presentation
  東京ビックサイト（東京都江東区）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PLANNED-24112005
[Presentation] BRCA変異陽性乳がんにおけるPrecision Medicine -基礎から臨床へ-2016
- Author(s)
  太田智彦
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PLANNED-24112005
[Presentation] TripleNegative型乳癌（Basal型）においてLSD1蛋白の過剰発現は予後不良因子である2016
- Author(s)
  永澤慧, 前田一郎, 太田智彦, 津川浩一郎
- Organizer
  第24回日本乳癌学会学術総会
- Place of Presentation
  東京ビックサイト（東京都江東区）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PLANNED-24112005
[Presentation] DNA損傷修復機構に関与するユビキチンE3リガーセの検討2016
- Author(s)
  敦賀智子, 岡田麻衣子, 黒田貴子, 宇井彩子, 太田智彦
- Organizer
  第24回日本乳癌学会学術総会
- Place of Presentation
  東京ビックサイト（東京都江東区）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PLANNED-24112005
[Presentation] BRCA変異陽性乳がんにおけるPrecision Medicine -基礎から臨床へ-2016
- Author(s)
  太田智彦
- Organizer
  第75回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-26290042
[Presentation] BRCA変異陽性乳がんにおけるPrecision Medicine -基礎から臨床へ-2016
- Author(s)
  太田智彦
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-16K15712
[Presentation] ドキシサイクリン誘導性BRCA1欠損ERα陽性細胞を用いた染色体不安定化機構の解析2016
- Author(s)
  黒田貴子, 岡田麻衣子, 敦賀智子, 太田智彦, 津川浩一郎
- Organizer
  第24回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-26290042
[Presentation] ドキシサイクリン誘導性BRCA1欠損ERα陽性細胞を用いた染色体不安定化機構の解析2016
- Author(s)
  黒田貴子, 岡田麻衣子, 敦賀智子, 太田智彦, 津川浩一郎
- Organizer
  第24回日本乳癌学会学術総会
- Place of Presentation
  東京ビックサイト（東京都江東区）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-16K15712
[Presentation] DNA損傷修復機構に関与するユビキチンE3リガーセの検討2016
- Author(s)
  敦賀智子, 岡田麻衣子, 黒田貴子, 宇井彩子, 太田智彦
- Organizer
  第24回日本乳癌学会学術総会
- Place of Presentation
  東京ビックサイト（東京都江東区）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-16K15712
[Presentation] HERC2 and its interactors in regulation of DNA damage response and cell cycle.2015
- Author(s)
  太田智彦
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-26290042
[Presentation] HERC2 and its interactors in regulation of DNA damage response and cell cycle.2015
- Author(s)
  太田智彦
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県・名古屋市)
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PLANNED-24112005
[Presentation] トランスレーショナルリサーチを進める上での問題点2015
- Author(s)
  太田智彦, 前田一郎, 津川浩一郎
- Organizer
  第23回日本乳癌学会学術総会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2015-07-03
- Data Source
  KAKENHI-PROJECT-26290042
[Presentation] トランスレーショナルリサーチを進める上での問題点2015
- Author(s)
  太田智彦, 前田一郎, 津川浩一郎
- Organizer
  第23回日本乳癌学会学術総会
- Place of Presentation
  東京国際フォーラム（東京都・千代田区）
- Year and Date
  2015-07-03
- Data Source
  KAKENHI-PLANNED-24112005
[Presentation] HERC2 and its interactors in regulation of DNA damage response and cell cycle.2015
- Author(s)
  太田智彦
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県・名古屋市)
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-26670730
[Presentation] トランスレーショナルリサーチを進める上での問題点2015
- Author(s)
  太田智彦, 前田一郎, 津川浩一郎
- Organizer
  第23回日本乳癌学会学術総会
- Place of Presentation
  東京国際フォーラム（東京都・千代田区）
- Year and Date
  2015-07-03
- Data Source
  KAKENHI-PROJECT-26670730
[Presentation] HP1 amma mediates BARD1 retention on Lys9-dimethylated histone H3 at sites of DNA damage2014
- Author(s)
  Tomohiko Ohta, Hiroyuki Nishikawa, Anna S. Sedukhina, Takayo Fukuda, Wenwen Wu
- Organizer
  Fusion Conference DNA Replication as a Source of DNA Damage
- Place of Presentation
  カサブランカ（モロッコ）
- Year and Date
  2014-10-02
- Data Source
  KAKENHI-PROJECT-26290042
[Presentation] BRCA1 retention at DNA double-strand breaks in homology-directed repair pathways2014
- Author(s)
  Tomohiko Ohta
- Organizer
  International Symposium on Homeostasis through development, life, and diseases
- Place of Presentation
  群馬大学（群馬県前橋市）
- Year and Date
  2014-11-07
- Data Source
  KAKENHI-PROJECT-26670730
[Presentation] BRCA1の新規クロマチン結合機構を標的としたがん治療戦略2014
- Author(s)
  太田智彦
- Organizer
  第15回ホルモンと癌研究会
- Place of Presentation
  艮陵会館（宮城県仙台市）
- Year and Date
  2014-07-04
- Data Source
  KAKENHI-PLANNED-24112005
[Presentation] Therapeutic strategy targeting the mechanism of BRCA1 retention at DNA damage sites via a histone modification.2014
- Author(s)
  太田智彦
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-26290042
[Presentation] BRCA1 retention at DNA double-strand breaks in homology-directed repair pathways2014
- Author(s)
  Tomohiko Ohta
- Organizer
  International Symposium on Homeostasis through development, life, and diseases
- Place of Presentation
  群馬大学（群馬県前橋市）
- Year and Date
  2014-11-07
- Data Source
  KAKENHI-PROJECT-26290042
[Presentation] BRCA1の新規DNA損傷応答メカニズムを標的とした治療戦略2014
- Author(s)
  太田智彦
- Organizer
  第22回日本乳癌学会学術総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2014-07-10
- Data Source
  KAKENHI-PROJECT-26670730
[Presentation] BRCA1のDNA損傷応答とヒストン修飾2014
- Author(s)
  太田智彦
- Organizer
  第19回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府豊中市）
- Year and Date
  2014-08-09
- Data Source
  KAKENHI-PROJECT-26670730
[Presentation] Therapeutic strategy targeting the mechanism of BRCA1 retention at DNA damage sites via a histone modification.2014
- Author(s)
  太田智彦
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-26670730
[Presentation] BRCA1のDNA損傷応答とヒストン修飾2014
- Author(s)
  太田智彦
- Organizer
  第19回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府豊中市）
- Year and Date
  2014-08-09
- Data Source
  KAKENHI-PROJECT-26290042
[Presentation] HP1 amma mediates BARD1 retention on Lys9-dimethylated histone H3 at sites of DNA damage2014
- Author(s)
  Tomohiko Ohta, Hiroyuki Nishikawa, Anna S. Sedukhina, Takayo Fukuda, Wenwen Wu
- Organizer
  Fusion Conference DNA Replication as a Source of DNA Damage
- Place of Presentation
  カサブランカ（モロッコ）
- Year and Date
  2014-10-02
- Data Source
  KAKENHI-PLANNED-24112005
[Presentation] BRCA1の新規クロマチン結合機構を標的としたがん治療戦略2014
- Author(s)
  太田智彦
- Organizer
  第15回ホルモンと癌研究会
- Place of Presentation
  艮陵会館（宮城県仙台市）
- Year and Date
  2014-07-04
- Data Source
  KAKENHI-PROJECT-26290042
[Presentation] ATM-dependent but RNF168-independent BRCA1/BARD1 retention at sites of DNA damage2014
- Author(s)
  Tomohiko Ohta, Hiroyuki Nishikawa, Anna S. Sedukhina, Takayo Fukuda, Wenwen Wu
- Organizer
  Benzon Symposium No 60 - Nuclear Regulation by Ubiquitin
- Place of Presentation
  コペンハーゲン（デンマーク）
- Year and Date
  2014-08-18
- Data Source
  KAKENHI-PROJECT-26290042
[Presentation] ATM-dependent but RNF168-independent BRCA1/BARD1 retention at sites of DNA damage2014
- Author(s)
  Tomohiko Ohta, Hiroyuki Nishikawa, Anna S. Sedukhina, Takayo Fukuda, Wenwen Wu
- Organizer
  Benzon Symposium No 60 - Nuclear Regulation by Ubiquitin
- Place of Presentation
  コペンハーゲン（デンマーク）
- Year and Date
  2014-08-18
- Data Source
  KAKENHI-PROJECT-26670730
[Presentation] BRCA1のDNA損傷応答とヒストン修飾2014
- Author(s)
  太田智彦
- Organizer
  第19回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府豊中市）
- Year and Date
  2014-08-09
- Data Source
  KAKENHI-PLANNED-24112005
[Presentation] HP1 amma mediates BARD1 retention on Lys9-dimethylated histone H3 at sites of DNA damage2014
- Author(s)
  Tomohiko Ohta, Hiroyuki Nishikawa, Anna S. Sedukhina, Takayo Fukuda, Wenwen Wu
- Organizer
  Fusion Conference DNA Replication as a Source of DNA Damage
- Place of Presentation
  カサブランカ（モロッコ）
- Year and Date
  2014-10-02
- Data Source
  KAKENHI-PROJECT-26670730
[Presentation] BRCA1の新規DNA損傷応答メカニズムを標的とした治療戦略2014
- Author(s)
  太田智彦
- Organizer
  第22回日本乳癌学会学術総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2014-07-10
- Data Source
  KAKENHI-PLANNED-24112005
[Presentation] ATM-dependent but RNF168-independent BRCA1/BARD1 retention at sites of DNA damage2014
- Author(s)
  Tomohiko Ohta, Hiroyuki Nishikawa, Anna S. Sedukhina, Takayo Fukuda, Wenwen Wu
- Organizer
  Benzon Symposium No 60 - Nuclear Regulation by Ubiquitin
- Place of Presentation
  コペンハーゲン（デンマーク）
- Year and Date
  2014-08-18
- Data Source
  KAKENHI-PLANNED-24112005
[Presentation] Therapeutic strategy targeting the mechanism of BRCA1 retention at DNA damage sites via a histone modification.2014
- Author(s)
  太田智彦
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PLANNED-24112005
[Presentation] BRCA1の新規DNA損傷応答メカニズムを標的とした治療戦略2014
- Author(s)
  太田智彦
- Organizer
  第22回日本乳癌学会学術総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2014-07-10
- Data Source
  KAKENHI-PROJECT-26290042
[Presentation] BRCA1の新規クロマチン結合機構を標的としたがん治療戦略2014
- Author(s)
  太田智彦
- Organizer
  第15回ホルモンと癌研究会
- Place of Presentation
  艮陵会館（宮城県仙台市）
- Year and Date
  2014-07-04
- Data Source
  KAKENHI-PROJECT-26670730
[Presentation] BRCA1 retention at DNA double-strand breaks in homology-directed repair pathways2014
- Author(s)
  Tomohiko Ohta
- Organizer
  International Symposium on Homeostasis through development, life, and diseases
- Place of Presentation
  群馬大学（群馬県前橋市）
- Year and Date
  2014-11-07
- Data Source
  KAKENHI-PLANNED-24112005
[Presentation] DNA損傷応答におけるBRCA1,Claspinおよび HERC2の相互作用2013
- Author(s)
  太田智彦
- Organizer
  第65回日本細胞生物学会大会
- Place of Presentation
  ウインクあいち(愛知県産業労働センター)
- Year and Date
  2013-06-21
- Data Source
  KAKENHI-PROJECT-23300358
[Presentation] DNA損傷応答とBRCA1ユビキチンリガーゼ2013
- Author(s)
  太田智彦
- Organizer
  第86回日本生化学学会大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2013-09-12
- Data Source
  KAKENHI-PROJECT-23300358
[Presentation] BRCA1-E3 inactivation leads to a failure of homologous recombination DNA repair in response to CPT-11 and PARPi2013
- Author(s)
  太田智彦
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2013-10-03
- Data Source
  KAKENHI-PROJECT-23300358
[Presentation] Homology-directed DNA repair competence as a possible biomarker for breast cancer chemosensitivity2013
- Author(s)
  太田智彦
- Organizer
  第11回日本臨床腫瘍学学会集会
- Place of Presentation
  仙台国際センター
- Year and Date
  2013-08-29
- Data Source
  KAKENHI-PROJECT-23300358
[Presentation] Agent-specific cellular chemosensitivity attributed to loss of BRCA1 E3 ligase activity2012
- Author(s)
  太田智彦
- Organizer
  15th International Congress on Hormonal Steroids and Hormones & Cancer
- Place of Presentation
  石川県立音楽堂
- Year and Date
  2012-11-15
- Data Source
  KAKENHI-PROJECT-23300358
[Presentation] DNA replication and checkpoint regulated by HERC2 and BRCA1 E3 ubiquitin ligases2012
- Author(s)
  太田智彦
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  さっぽろ芸文館
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-23300358
[Presentation] DNA replication and checkpoint regulated by HERC2 and BRCA1 E3 ubiquitin ligases2012
- Author(s)
  太田　智彦
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  さっぽろ芸文館（北海道）
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PLANNED-24112005
[Presentation] Agent-specific cellular chemosensitivity attributed to loss of BRCA1 E3 ligase activity2012
- Author(s)
  太田　智彦
- Organizer
  15th International Congress on Hormonal Steroids and Hormones Cancer
- Place of Presentation
  石川県立音楽堂（石川県）
- Year and Date
  2012-11-15
- Data Source
  KAKENHI-PLANNED-24112005
[Presentation] トリプルネガティブ乳癌に対する治療戦略2011
- Author(s)
  太田智彦
- Organizer
  第19回日本乳癌学会学術集会プレジデンシャルシンポジウム
- Place of Presentation
  仙台国際センター東北大学百周年記念会館(宮城県)
- Year and Date
  2011-09-04
- Data Source
  KAKENHI-PROJECT-23300358
[Presentation] トリプルネガティブ乳癌に対する治療戦略2011
- Author(s)
  太田智彦
- Organizer
  第19回日本乳癌学会学術集会ブレジデンシャルシンポジウム
- Place of Presentation
  仙台国際センター東北大学百周年記念会館(宮城県)
- Year and Date
  2011-09-04
- Data Source
  KAKENHI-PUBLICLY-23131514
[Presentation] トリプルネガティブ乳癌に対する治療戦略2011
- Author(s)
  太田智彦
- Organizer
  第19回日本乳癌学会学術集会
- Place of Presentation
  仙台国際センター東北大学百周年記念会館
- Year and Date
  2011-09-04
- Data Source
  KAKENHI-PROJECT-23300358
[Presentation] 乳がんのDNA相同組換え修復異常とユビキチン2010
- Author(s)
  太田智彦
- Organizer
  第69回日本癌学会学術総会、シンポジウム
- Place of Presentation
  大阪(大阪国際会議場)
- Data Source
  KAKENHI-PROJECT-20591557
[Presentation] The DNA damage repair pathway in breast cancer chemotherapy2010
- Author(s)
  Tomohiko Ohta
- Organizer
  The 23rd International Symposium of the Foundation for Promotion of Cancer Research "Recent Progress on Breast
- Place of Presentation
  東京(国立がんセンター)
- Data Source
  KAKENHI-PROJECT-20591557
[Presentation] 乳がんのDNA相同組換え修復異常とユビキチン2010
- Author(s)
  太田智彦
- Organizer
  第69回日本癌学会学術総会・シンポジウム
- Place of Presentation
  大阪国際会議場(大阪)
- Data Source
  KAKENHI-PROJECT-20591557
[Presentation] DNA損傷応答と乳癌の薬剤感受性2010
- Author(s)
  太田智彦
- Organizer
  第18回日本乳癌学会学術総会・シンポジウム
- Place of Presentation
  ロイトン札幌(北海道)
- Data Source
  KAKENHI-PROJECT-20591557
[Presentation] Recruitment of phosphorylated NPM1 to sites of DNA damage through RNF8-dependent ubiquitin conjugates.2010
- Author(s)
  太田智彦
- Organizer
  EMBO Workshop-The interface between the ubiquitin family and the DNA damage response.
- Place of Presentation
  Hotel Istra (Croatia)
- Data Source
  KAKENHI-PROJECT-20591557
[Presentation] DNA損傷応答と乳癌の薬剤感受性2010
- Author(s)
  太田智彦
- Organizer
  第18回日本乳癌学会学術総会、シンポジウム
- Place of Presentation
  北海道(ロイトン札幌)
- Data Source
  KAKENHI-PUBLICLY-21025032
[Presentation] The DNA damage repair pathway in breast cancer chemotherapy2010
- Author(s)
  Tomohiko Ohta
- Organizer
  The 23rd International Symposium of the Foundation for Promotion of Cancer Research "Recent Progress on Breast
- Place of Presentation
  東京(国立がんセンター)
- Data Source
  KAKENHI-PUBLICLY-21025032
[Presentation] Recruitment of phosphorylated NPM1 to sites of DNA damage through RNF8-dependent ubiquitin conjugates.2010
- Author(s)
  Tomohiko Ohta
- Organizer
  EMBO Workshop-The interface between the ubiquitin family and the DNA damage response.-
- Place of Presentation
  Croatia (Hotel Istra)
- Data Source
  KAKENHI-PROJECT-20591557
[Presentation] DNA損傷応答と乳癌の薬剤感受性2010
- Author(s)
  太田智彦
- Organizer
  第18回日本乳癌学会学術総会、シンポジウム
- Place of Presentation
  北海道(ロイトン札幌)
- Data Source
  KAKENHI-PROJECT-20591557
[Presentation] The DNA damage repair pathway in breast cancer chemotherapy.2010
- Author(s)
  太田智彦
- Organizer
  The 23rd International Symposium of the Foundation for Promotion of Cancer Research
- Place of Presentation
  国立がんセンター Recent Progress on Breast Cancer(東京都)
- Data Source
  KAKENHI-PROJECT-20591557
[Presentation] 乳がんのDNA相同組換え修復異常とユビキチン2010
- Author(s)
  太田智彦
- Organizer
  第69回日本癌学会学術総会、シンポジウム
- Place of Presentation
  大阪(大阪国際会議場)
- Data Source
  KAKENHI-PUBLICLY-21025032
[Presentation] Recruitment of phosphorylated NPM1 to sites of DNA damage through RNF8-dependent ubiquitin conjugates.2010
- Author(s)
  Tomohiko Ohta
- Organizer
  EMBO Workshop-The interface between the ubiquitin family and the DNA damage response.-
- Place of Presentation
  Croatia (Hotel Istra)
- Data Source
  KAKENHI-PUBLICLY-21025032
[Presentation] BRCA1機能不全をtargetにした乳癌の化学療法2009
- Author(s)
  太田智彦
- Organizer
  第109回日本外科学会定期学術集会
- Place of Presentation
  福岡国際会議場(福岡県)
- Year and Date
  2009-04-02
- Data Source
  KAKENHI-PUBLICLY-21025032
[Presentation] BRCA1機能不全をtargetにした乳癌の化学療法2009
- Author(s)
  太田智彦
- Organizer
  第109回日本外科学会定期学術集会
- Place of Presentation
  福岡国際会議場(福岡県)
- Year and Date
  2009-04-02
- Data Source
  KAKENHI-PROJECT-20591557
[Presentation] 乳癌の化学療法感受性とBRCA12009
- Author(s)
  太田智彦
- Organizer
  第19回乳癌基礎研究会
- Place of Presentation
  伊香保温泉(群馬県)
- Year and Date
  2009-07-25
- Data Source
  KAKENHI-PROJECT-20058036
[Presentation] 乳癌の化学療法感受性とBRCA12009
- Author(s)
  太田智彦
- Organizer
  第19回乳癌基礎研究会
- Place of Presentation
  伊香保温泉(群馬県)
- Year and Date
  2009-07-25
- Data Source
  KAKENHI-PROJECT-20591557
[Presentation] BRCA1機能不全をtargetにした乳癌の化学療法2009
- Author(s)
  太田智彦
- Organizer
  第109回日本外科学会定期学術集会
- Place of Presentation
  福岡国際会議場(福岡県)
- Year and Date
  2009-04-02
- Data Source
  KAKENHI-PROJECT-20058036
[Presentation] 乳癌の化学療法感受性とBRCA12009
- Author(s)
  太田智彦
- Organizer
  第19回乳癌基礎研究会
- Place of Presentation
  伊香保温泉(群馬県)
- Year and Date
  2009-07-25
- Data Source
  KAKENHI-PUBLICLY-21025032
[Presentation] DNA double-strand break repair mediated by BRCA1.2008
- Author(s)
  太田智彦
- Organizer
  26th Congress of the International Association for Breast Cancer Research.
- Place of Presentation
  岡山県
- Year and Date
  2008-09-23
- Data Source
  KAKENHI-PROJECT-20591557
[Presentation] BRCA1カスケードによる遺伝子恒常性維持と家族性腫瘍2008
- Author(s)
  太田智彦
- Organizer
  第1 4回日本家族性腫瘍学会学術総会
- Place of Presentation
  東京
- Year and Date
  2008-06-21
- Data Source
  KAKENHI-PROJECT-20591557
[Presentation] Candidate substrates of BRCAl in its multiple cellular functions2008
- Author(s)
  Tomohiko Ohta
- Organizer
  2^<nd> JCA-AACR special Joint Conference : The latest Advance in Breast Cancer Research From Basic Science to Therapeutics
- Place of Presentation
  兵庫
- Year and Date
  2008-07-14
- Data Source
  KAKENHI-PROJECT-20591557
[Presentation] BRCA1の機能から考えたBasal-like乳癌の薬剤感受性2008
- Author(s)
  太田智彦
- Organizer
  第16回日本乳癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2008-09-27
- Data Source
  KAKENHI-PROJECT-20058036
[Presentation] BRCA1を標的とするユビキチンリガーゼの同定2008
- Author(s)
  太田智彦
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20058036
[Presentation] BRCA1を標的とするユビキチンリガーゼの同定2008
- Author(s)
  太田智彦
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20591557
[Presentation] Cooperation of BRCA1 and ubiquitin in the DNA damage response2008
- Author(s)
  Ohta T.
- Organizer
  The 23rd Nagoya international cancer treatment symposium
- Place of Presentation
  Nagoya
- Year and Date
  2008-01-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591446
[Presentation] DNA double-strand break repair mediated by BRCA12008
- Author(s)
  Tomohiko Ohta
- Organizer
  26^<th> Congress of the International Association fix Breast Cancer Research
- Place of Presentation
  岡山
- Year and Date
  2008-09-23
- Data Source
  KAKENHI-PROJECT-19044042
[Presentation] Cooperation of BRCA1 and ubiquitin in the DNA damage response2008
- Author(s)
  太田智彦
- Organizer
  第23回名古屋癌治療国際シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2008-01-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591446
[Presentation] Cooperation of BRCA1 and ubiquitin in the DNA damage response.2008
- Author(s)
  Tomohiko Ohta
- Organizer
  第23回名古屋癌治療国際シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2008-01-26
- Data Source
  KAKENHI-PROJECT-19044042
[Presentation] BRCA1の機能から考えたBasal-like乳癌の薬剤感受性2008
- Author(s)
  太田智彦
- Organizer
  第16回日本乳癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2008-09-27
- Data Source
  KAKENHI-PROJECT-20591557
[Presentation] Cooperation of BRCA1 and ubiquitin in the DNA damage response2008
- Author(s)
  Ohta T.
- Organizer
  The 23rd Nagoya international cancer treatment symposium
- Place of Presentation
  Nagoya
- Year and Date
  2008-01-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591486
[Presentation] Cooperation of BRCAl and ubiquitin in the DNA damage response.2008
- Author(s)
  Tomohiko Ohta
- Organizer
  第23回名古屋癌治療国際シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2008-01-26
- Data Source
  KAKENHI-PROJECT-18591446
[Presentation] BRCA1の機能から考えたBasal-like乳癌の薬剤感受性2008
- Author(s)
  太田智彦
- Organizer
  第16回日本乳癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2008-09-27
- Data Source
  KAKENHI-PROJECT-19044042
[Presentation] DNA double-strand break repair mediated by BRCA12008
- Author(s)
  Tomohiko Ohta
- Organizer
  26^<th> Congress of the International Association for Breast Cancer Research
- Place of Presentation
  岡山
- Year and Date
  2008-09-23
- Data Source
  KAKENHI-PROJECT-20058036
[Presentation] Candidate substrates of BRCA1 in its multiple cellular functions.2008
- Author(s)
  太田智彦
- Organizer
  2nd JCA-AACR special Joint Conference : The latest Advance in Breast Cancer Research From Basic Science to Therapeutics.
- Place of Presentation
  兵庫県
- Year and Date
  2008-07-14
- Data Source
  KAKENHI-PROJECT-20591557
[Presentation] DNA double-strand break repair mediated by BRCAl2008
- Author(s)
  Tomohiko Ohta
- Organizer
  26^<th> Congress of the International Association for Breast Cancer Research
- Place of Presentation
  岡山
- Year and Date
  2008-09-23
- Data Source
  KAKENHI-PROJECT-20591557
[Presentation] Candidate substrates of BRCA1 in its multiple cellular functions2008
- Author(s)
  Tomohiko Ohta
- Organizer
  2^<nd> JCA-AACR special Joint Conference : The latest Advance in Braast Cancer Research From Basic Science to Therapeutics
- Place of Presentation
  兵庫
- Year and Date
  2008-07-14
- Data Source
  KAKENHI-PROJECT-20058036
[Presentation] BRCA1カスケードによる遺伝子恒常性維持と家族性腫瘍2008
- Author(s)
  太田智彦
- Organizer
  第14回日本家族性腫瘍学会学術総会
- Place of Presentation
  東京
- Year and Date
  2008-06-21
- Data Source
  KAKENHI-PROJECT-20058036
[Presentation] BRCA1カスケードによる遺伝子恒常性維持と家族性腫瘍2008
- Author(s)
  太田智彦
- Organizer
  第14回日本家族性腫瘍学会学術総会
- Place of Presentation
  東京
- Year and Date
  2008-06-21
- Data Source
  KAKENHI-PROJECT-19044042
[Presentation] Candidate substrates of BRCA1 in its multiple cellular functions2008
- Author(s)
  Tomohiko Ohta
- Organizer
  2^<nd> JCA-AACR special Joint Conference : The latest Advance in Breast Cancer Research From Basic Science to Therapeutics
- Place of Presentation
  兵庫
- Year and Date
  2008-07-14
- Data Source
  KAKENHI-PROJECT-19044042
[Presentation] BRCAlを標的とするュビキチンリガーゼの同定2008
- Author(s)
  太田智彦
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20591557
[Presentation] BRCA1の機能から考えたBasal-like乳癌の薬剤感受性2008
- Author(s)
  太田智彦
- Organizer
  第16回日本乳癌学会学術総会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2008-09-27
- Data Source
  KAKENHI-PROJECT-20591557
[Presentation] BRCA1カスケードによる遺伝子恒常性維持と家族性腫瘍2008
- Author(s)
  太田智彦
- Organizer
  第14回日本家族性腫瘍学会学術総会
- Place of Presentation
  東京都
- Year and Date
  2008-06-21
- Data Source
  KAKENHI-PROJECT-20591557
[Presentation] BRCA1を標的とするユビキチンリガーゼの同定2008
- Author(s)
  太田智彦
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19044042
[Presentation] 細胞周期およびDNA損傷におけるBRCA1ユビキチンリガーゼの分子機能2007
- Author(s)
  太田智彦, et. al.
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-18591446
[Presentation] 細胞周期およびDNA損傷反応におけるBRCA1ユビキチンリガーゼの分子機能2007
- Author(s)
  太田智彦, 他
- Organizer
  第66回日本癌学会総会・シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591446
[Presentation] Molecular functions of BRCA1E3 ubiquitin ligase in cell cycle and DNA damage response2007
- Author(s)
  Ohta T., Wu W, Fukuda M.
- Organizer
  The 66th annual meeting of the Japanese cancer association
- Place of Presentation
  Yokohama
- Year and Date
  2007-10-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591486
[Presentation] Molecular functions of BRCA1E3 ubiquitin ligase in cell cycle and DNA damage response2007
- Author(s)
  Ohta T., Wu W., Fukuda M.
- Organizer
  The 66th annual meeting of the Japanese cancer association
- Place of Presentation
  Yokohama
- Year and Date
  2007-10-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591446
[Presentation] Molecular functions of BRCA1 E3 ubiquitin ligase in cell cycle and DNA damage response2007
- Author(s)
  Ohta T.
- Organizer
  The 66th annual meeting of the Japanese cancer association
- Place of Presentation
  Yokohama
- Year and Date
  2007-10-03
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591486
[Presentation] 細胞周期およびDNA損傷におけるBRCA1ユビキチンリガーゼの分子機能2007
- Author(s)
  太田智彦, et. al.
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19044042
[Presentation] Roles of BRCA1's enzyme activity in breast and ovarian tumor Suppression2006
- Author(s)
  Ohta T.
- Organizer
  The 95th annual congress of the Japanese society of pathology
- Place of Presentation
  Siniuku
- Year and Date
  2006-04-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591486
[Presentation] The enzyme activity of breast and ovarian tumor suppresser BRCA12006
- Author(s)
  Ohta T.
- Organizer
  The 12th annual congress of the Japanese society for familial tumors
- Place of Presentation
  Suita
- Year and Date
  2006-06-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591486
[Presentation] 乳癌および卵巣癌抑制におけるBRCA1酵素活性の役割2006
- Author(s)
  太田智彦
- Organizer
  第95回日本病理学会総会・シンポジウム
- Place of Presentation
  新宿
- Year and Date
  2006-04-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591446
[Presentation] Breast and ovarian tumor suppression by BRCA1's enzyme activity2006
- Author(s)
  Ohta T.
- Organizer
  The 43th congress of the Japanese society of molecular medicine
- Place of Presentation
  Sapporo
- Year and Date
  2006-07-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591446
[Presentation] The enzyme activity of breast and ovarian tumor suppresser BRCA12006
- Author(s)
  Ohta T.
- Organizer
  The 95th annual congress of the Japanese society of pathology
- Place of Presentation
  Sinjuku
- Year and Date
  2006-04-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591486
[Presentation] Ubiquitin ligase activity of BRCA1,a hub protein that regulates multiple cellular pathways2006
- Author(s)
  Ohta T.
- Organizer
  MBSJ forum 2006 of the molecular biology society of Japan
- Place of Presentation
  Nagoya
- Year and Date
  2006-12-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591486
[Presentation] BRCA1の酵素活性による乳癌および卵巣癌抑制2006
- Author(s)
  太田智彦
- Organizer
  第43回日本臨床分子医学会学術集会・シンポジウム
- Place of Presentation
  札幌
- Year and Date
  2006-07-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591446
[Presentation] Roles of BRCA1's Enzyme Activity in the Maintenance of Genomic Stability2006
- Author(s)
  Ohta T.
- Organizer
  The 49th annual meeting of the Japan radiation research society
- Place of Presentation
  Sapporo
- Year and Date
  2006-09-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591486
[Presentation] Ubiquitin ligase activity of BRCA1, a hub protein that regulates multiple cellular pathways2006
- Author(s)
  Ohta T., Wu W, Fukuda M.
- Organizer
  MBSJ forum 2006 of the molecular biology society of Japan
- Place of Presentation
  Nagoya
- Year and Date
  2006-12-07
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591486
[Presentation] ゲノム安定性維持におけるBRCA1酵素活性の役割2006
- Author(s)
  太田智彦
- Organizer
  第49回日本放射線影響学会・シンポジウム
- Place of Presentation
  札幌
- Year and Date
  2006-09-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591446
[Presentation] 多様な細胞内径路を制御するBRCA1のユビキチンリガーゼ活性2006
- Author(s)
  太田智彦, 他
- Organizer
  日本分子生物学会2006フォーラム・シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2006-12-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591446
[Presentation] Ubiquitin ligase activity of BRCA1, a hub protein that regulates multiple cellular pathways2006
- Author(s)
  Ohta T., Wu W., Fukuda M.
- Organizer
  MBSJ forum 2006 of the molecular biology society of Japan
- Place of Presentation
  Nagoya
- Year and Date
  2006-12-07
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591446
[Presentation] 乳癌および卵巣癌抑制遺伝子産物BRCA1の酵素活性2006
- Author(s)
  太田智彦
- Organizer
  第12回日本家族性腫瘍学会学術総会・シンポジウム
- Place of Presentation
  吹田
- Year and Date
  2006-06-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591446
[Presentation] The enzyme activity of breast and ovarian tumor suppresser BRCA12006
- Author(s)
  Ohta T.
- Organizer
  The 12th annual congress of the Japanese society for familial tumors
- Place of Presentation
  Suita
- Year and Date
  2006-06-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591446
[Presentation] Breast and ovarian tumor suppression by BRCA1's enzyme activity2006
- Author(s)
  Ohta T.
- Organizer
  The 43th congress of the Japanese society of molecular medicine
- Place of Presentation
  Sapporo
- Year and Date
  2006-07-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591486
[Presentation] Roles of BRCA1's Enzyme Activity in the Maintenance of Genomic Stability2006
- Author(s)
  Ohta T.
- Organizer
  The 49th annual meeting of the Japan radiation research society
- Place of Presentation
  Sapporo
- Year and Date
  2006-09-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591446
[Presentation] Roles of BRCA1's enzyme activity in breast and ovarian tumor Suppression2006
- Author(s)
  Ohta T.
- Organizer
  The 95th annual congress of the Japanese society of pathology
- Place of Presentation
  Sinjuku
- Year and Date
  2006-04-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591446
[Presentation] DNA損傷応答とBRCA1ユビキチンリガーゼ
- Author(s)
  太田　智彦
- Organizer
  第86回日本生化学学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23300358
[Presentation] Agent-specific cellular chemosensitivity attributed to loss of BRCA1 E3 ligase activity
- Author(s)
  太田　智彦
- Organizer
  15th International Congress on Hormonal Steroids and Hormones & Cancer
- Place of Presentation
  石川県立音楽堂（石川県）
- Data Source
  KAKENHI-PROJECT-23300358
[Presentation] BRCA1-E3 inactivation leads to a failure of homologous recombination DNA repair in response to CPT-11 and PARPi
- Author(s)
  太田　智彦
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PLANNED-24112005
[Presentation] DNA損傷応答とBRCA1ユビキチンリガーゼ
- Author(s)
  太田　智彦
- Organizer
  第86回日本生化学学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PLANNED-24112005
[Presentation] BRCA1-E3 inactivation leads to a failure of homologous recombination DNA repair in response to CPT-11 and PARPi
- Author(s)
  太田　智彦
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23300358
[Presentation] DNA損傷応答におけるBRCA1, ClaspinおよびHERC2の相互作用
- Author(s)
  太田　智彦
- Organizer
  第65回日本細胞生物学会大会
- Place of Presentation
  ウインクあいち（愛知県産業労働センター）
- Data Source
  KAKENHI-PROJECT-23300358
[Presentation] DNA損傷応答におけるBRCA1, ClaspinおよびHERC2の相互作用
- Author(s)
  太田　智彦
- Organizer
  第65回日本細胞生物学会大会
- Place of Presentation
  ウインクあいち（愛知県産業労働センター）
- Data Source
  KAKENHI-PLANNED-24112005
[Presentation] Homology-directed DNA repair competence as a possible biomarker for breast cancer chemosensitivity
- Author(s)
  太田　智彦
- Organizer
  第11回日本臨床腫瘍学会集会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-23300358
[Presentation] DNA replication and checkpoint regulated by HERC2 and BRCA1 E3 ubiquitin ligases
- Author(s)
  太田　智彦
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  さっぽろ芸文館（北海道）
- Data Source
  KAKENHI-PROJECT-23300358
[Presentation] Homology-directed DNA repair competence as a possible biomarker for breast cancer chemosensitivity
- Author(s)
  太田　智彦
- Organizer
  第11回日本臨床腫瘍学会集会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PLANNED-24112005

1. FUKUDA Mamoru (50081724)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. OGATA Haruki (60267581)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. BOKU Narikazu (50505948)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. TSUGAWA Koichiro (60313657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. NAKADA Shinichiro (70548528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TADOKORO Mamoru (80081644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TAKAKUWA Toshifumi (90121201)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ARIMURA Toshihiro (70232072)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OTSUBO Takehito (50398971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 中島利博 (90260752)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 福田護 (70059442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 渡部省二 (30113020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. WU Wenwen

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results
14. KATO Akihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. UMEZU Tomohiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. SUZUKI Hiromu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 城村由和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 高田穣

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
19. 平直江

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 西川裕之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 中村修平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 勝木陽子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 井ノ上逸朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 鈴木穣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 中西真

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OHTA Tomohiko 太田 智彦

Research Projects

Research Products

Co-Researchers

乳がんのDNA損傷修復とcGAS-STING経路を制御するシグナル伝達系の解析Principal Investigator

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Study of the mechanism underlying the acquired hormone therapy resistance in breast cancerPrincipal Investigator

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Analyses of the mechanisms for DNA G-quadruplex resolution as a molecular basis of the treatment of breast and ovarian cancer.Principal Investigator

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A study of mechanism underlying carcinogenesis promoted by estrogen receptor in BRCA1 deficient cellsPrincipal Investigator

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Functional analysis of BRCA1 as the molecular basis of breast cancer therapyPrincipal Investigator

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Unravelling the mechanism of ovarian carcinogenesis caused by BRCA1 depletion and estrogen actionPrincipal Investigator

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Regulation of DNA repair machinery by K6- and K63-linked polyubiquitin chainsPrincipal Investigator

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DNA相同組替え修復機構におけるBRCA1ユビキチンリガーゼ活性の役割Principal Investigator

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Research on the breast cancer chemotherapy targeting synthetic lethality caused by the factors in the DNA damage repair pathways.Principal Investigator

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BRCA1ユビキチンリガーゼによるDNA損傷応答Principal Investigator

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HERC2によるS期およびG2/M期チェックポイント制御機構の解析Principal Investigator

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Analyses of DNA damage response to neoadjuvant chemotherapy in basal-like breast cancerPrincipal Investigator

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BRCA1ユビキチンリガーゼによる乳癌抑制機構の解析Principal Investigator

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OHTA Tomohiko 太田智彦