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OHTA Tomohiko  太田 智彦

ORCIDConnect your ORCID iD *help
Researcher Number 60233136
Other IDs
External Links
Affiliation (Current) 2025: 聖マリアンナ医科大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help 2016 – 2024: 聖マリアンナ医科大学, 医学研究科, 教授
2010 – 2015: St.Marianna University School of Medicine, 医学(系)研究科(研究院), 教授
2007 – 2009: St.Marianna University School of Medicine, Department of Surgery, Associate Professor
2004 – 2006: 聖マリアンナ医科大学, 医学部, 助教授
1999 – 2003: St.Marianna University School of Medicine, Department of Surgery, Assistant Professor, 医学部, 講師
1994 – 1998: St.Marianna University, 1st Department of Surgery, Associate, 医学部, 助手
Review Section/Research Field
Principal Investigator
Biological Sciences / General surgery / General surgery / Basic Section 55010:General surgery and pediatric surgery-related / Obstetrics and gynecology / Tumor biology / Biological Sciences / Tumor diagnosis
Except Principal Investigator
General surgery / Digestive surgery
Keywords
Principal Investigator
BRCA1 / BARD1 / DNA損傷 / DNA修復 / RINGフィンガー / ユビキチンリガーゼ / 家族性乳癌 / 乳癌 / RPB8 / ユビキチン … More / Nucleophosmin / RING finger / 変異 / 細胞周期 / KDM4B / ubiquitin ligase / familial breast cancer / ヘテロクロマチン / エストロゲン / ubiquitin / 薬剤感受性 / DUB / HERC2 / 癌 / cGAS-STING / RSK / 免疫チェックポイント / HER2 / ER / 内分泌療法 / AKT / Fbxo22 / 子宮内膜がん / 乳がん / G4安定化剤 / グアニン4重鎖 / 相同組換修復 / 卵巣癌 / 膵癌 / 臓器特異性 / Chk2 / アポトーシス / 染色体不安定性 / ERα / Nucleophosm / nucleophosmin / ヌクレオフォスミン / Ligase / breast cancer / ヘテロダイマー / タンパク質分解 / 卵管癌 / 治療 / 非癌遺伝子依存性 / 癌化学療法 / 合成致死性 / DNA複製 / NPM1 / Basal-like 乳癌 / 術前化学療 / 術前化学療法 / Basal-like乳癌 / チェックポイント / チェックポイン / CDK2 / ユビキンリガーゼ / p27 / cdc2 variant / G0期 / Rb / Cyclin / cdk / G0静止 … More
Except Principal Investigator
p53 / APC / 家族性大腸ポリポーシス / EDD / hyd / scFv / CDK2ΔT / T-loop / variant / breast cancer / 細胞周期 / western blotting / c-erbB-2 / p34^<cdc2> / 乳癌 / colon cancer / tumor suppressor / 大腸癌 / 癌抑制遺伝子 / RING finger / ubiquitin ligase / protein degradation / gene therapy / RINGフィンガー / ユビキチンリガーゼ / ScFv / タンパク質分解 / 遺伝子治療 / CDC2ΔT / cell cycle / RT-PCR / Δcdk2 / Δcdc2 / p21 / cdk2 / cdc2 / CDK2 / CDC2 / mammography / immunostaining / non-palpable breast cancer / カテプシンD / c-erbB / P34^<cdc2> / マンモグラフィ / 免疫染色 / 非触知 Less
  • Research Projects

    (25 results)
  • Research Products

    (288 results)
  • Co-Researchers

    (25 People)
  •  乳がんのDNA損傷修復とcGAS-STING経路を制御するシグナル伝達系の解析Principal Investigator

    • Principal Investigator
      太田 智彦
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      St. Marianna University School of Medicine
  •  Study of the mechanism underlying the acquired hormone therapy resistance in breast cancerPrincipal Investigator

    • Principal Investigator
      Ohta Tomohiko
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      St. Marianna University School of Medicine
  •  Analyses of the mechanisms for DNA G-quadruplex resolution as a molecular basis of the treatment of breast and ovarian cancer.Principal Investigator

    • Principal Investigator
      Ohta Tomohiko
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor biology
    • Research Institution
      St. Marianna University School of Medicine
  •  A study of mechanism underlying carcinogenesis promoted by estrogen receptor in BRCA1 deficient cellsPrincipal Investigator

    • Principal Investigator
      OHTA Tomohiko
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      St. Marianna University School of Medicine
  •  Functional analysis of BRCA1 as the molecular basis of breast cancer therapyPrincipal Investigator

    • Principal Investigator
      OHTA Tomohiko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor biology
    • Research Institution
      St. Marianna University School of Medicine
  •  Unravelling the mechanism of ovarian carcinogenesis caused by BRCA1 depletion and estrogen actionPrincipal Investigator

    • Principal Investigator
      OHTA Tomohiko
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      St. Marianna University School of Medicine
  •  Regulation of DNA repair machinery by K6- and K63-linked polyubiquitin chainsPrincipal Investigator

    • Principal Investigator
      OHTA Tomohiko
    • Project Period (FY)
      2012 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      St. Marianna University School of Medicine
  •  DNA相同組替え修復機構におけるBRCA1ユビキチンリガーゼ活性の役割Principal Investigator

    • Principal Investigator
      太田 智彦
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      St. Marianna University School of Medicine
  •  Research on the breast cancer chemotherapy targeting synthetic lethality caused by the factors in the DNA damage repair pathways.Principal Investigator

    • Principal Investigator
      OHTA Tomohiko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor diagnosis
    • Research Institution
      St. Marianna University School of Medicine
  •  BRCA1ユビキチンリガーゼによるDNA損傷応答Principal Investigator

    • Principal Investigator
      太田 智彦
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      St. Marianna University School of Medicine
  •  HERC2によるS期およびG2/M期チェックポイント制御機構の解析Principal Investigator

    • Principal Investigator
      太田 智彦
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      St.Marianna University School of Medicine
  •  Analyses of DNA damage response to neoadjuvant chemotherapy in basal-like breast cancerPrincipal Investigator

    • Principal Investigator
      OHTA Tomohiko
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      St.Marianna University School of Medicine
  •  BRCA1ユビキチンリガーゼによる乳癌抑制機構の解析Principal Investigator

    • Principal Investigator
      太田 智彦
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      St.Marianna University School of Medicine
  •  Study of DNA repair mechanisms that affect chemosensitivity of breast cancerPrincipal Investigator

    • Principal Investigator
      OHTA Tomohiko
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      St.Marianna University School of Medicine
  •  The Role in APC stability control mechanism by EDD

    • Principal Investigator
      OTSUBO Takehito
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      St.Marianna University School of Medicine
  •  細胞周期におけるBRCA1-BARD1ユビキチンリガーゼ活性の調節機構Principal Investigator

    • Principal Investigator
      太田 智彦
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      St. Marianna University School of Medicine
  •  Mechanisms that regulate chromosomal stability through the ubiquitin lipase activity of BRCA1Principal Investigator

    • Principal Investigator
      OHTA Tomohiko
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      St.Marianna University School of Medicine
  •  ユビキチンリガーゼBRCA1-BARD1によるDNA修復および転写の制御Principal Investigator

    • Principal Investigator
      太田 智彦
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      St. Marianna University School of Medicine
  •  BRCA1-BARD1ヘテロダイマーユビキチンリガーゼによる細胞周期制御Principal Investigator

    • Principal Investigator
      太田 智彦
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      St. Marianna University School of Medicine
  •  Selective degradation of p53 mutant by an engineered ScFv-linked ubiquitin ligase

    • Principal Investigator
      FUKUDA Mamoru
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      St. Marianna University School of Medicine
  •  Elucidation of substrates and analysis of the function of BRCA 1 ubiquitin ligasePrincipal Investigator

    • Principal Investigator
      TOMOHIKO Ohta
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      St. Marianna University School of Medicine
  •  Molecular Cloning and Functional Analysis of CDK Variant Expressed in Breast Cancer Tissues

    • Principal Investigator
      FUKUDA Mamoru
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      St.Marianna University School of Medicine
  •  静止期癌細胞の細胞周期導入時においてG1/Sに先行する未知のG0/G1 eventPrincipal Investigator

    • Principal Investigator
      太田 智彦
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      General surgery
    • Research Institution
      St. Marianna University School of Medicine
  •  癌細胞におけるLRP蛋白細胞外ドメインの糖鎖形成不全と細胞増殖抑制との関係Principal Investigator

    • Principal Investigator
      太田 智彦
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      General surgery
    • Research Institution
      St. Marianna University School of Medicine
  •  Proliferative activities of non-palpable breast cancer detected by mammography

    • Principal Investigator
      FUKUDA Mamoru, 福田 護
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      St.Marianna University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent

  • [Book] 乳癌診療 state of the art - 科学に基づく最新診療「遺伝性乳癌に対する遺伝子修復不全標的治療」2022

    • Author(s)
      太田智彦
    • Total Pages
      5
    • Publisher
      医歯薬出版株式会社
    • Data Source
      KAKENHI-PROJECT-20H03748
  • [Book] Hereditary Breast and Ovarian Cancer「Molecular Basis of BRCA1 and BRCA2: Homologous Recombination Deficiency and Tissue-Specific Carcinogenesis」2021

    • Author(s)
      Ohta T, Wu W
    • Total Pages
      15
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-20H03748
  • [Book] 乳腺腫瘍学「7. BRCA変異診断、ゲノム診断」2020

    • Author(s)
      太田智彦
    • Total Pages
      4
    • Publisher
      金原出版
    • Data Source
      KAKENHI-PROJECT-20H03748
  • [Book] 医学のあゆみ「BRCA遺伝子変異による臓器特異的な発がん」2020

    • Author(s)
      郷田敦史, 呉文文, 太田智彦
    • Total Pages
      5
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-20H03748
  • [Book] メディカル・サイエンス・ダイジェスト「DNA相同組換え修復とユビキチン」2019

    • Author(s)
      朱明章, 太田智彦
    • Total Pages
      4
    • Publisher
      ニュー・サイエンス社
    • Data Source
      KAKENHI-PROJECT-17H03585
  • [Book] がん分子標的治療「がん治療分子標的としてのDNA相同組み換え修復異常」2019

    • Author(s)
      朱明章, 呉文文, 太田智彦
    • Total Pages
      8
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-17H03585
  • [Book] BRCA1/2の基礎とPARP阻害剤2018

    • Author(s)
      太田智彦.
    • Total Pages
      9
    • Publisher
      乳癌の臨床
    • Data Source
      KAKENHI-PROJECT-17H03585
  • [Book] 臨床医のための乳腺基礎医学「乳癌におけるDNA損傷と修復不全」2018

    • Author(s)
      頼勇強, 太田智彦
    • Total Pages
      5
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-17H03585
  • [Book] 臨床医のための乳腺基礎医学「乳癌におけるDNA損傷と修復不全」2018

    • Author(s)
      頼勇強, 太田智彦
    • Total Pages
      5
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-16K15712
  • [Book] BRCA1/2の基礎とPARP阻害剤2018

    • Author(s)
      太田智彦
    • Total Pages
      9
    • Publisher
      乳癌の臨床
    • Data Source
      KAKENHI-PROJECT-26290042
  • [Book] BRCA1/2の基礎とPARP阻害剤2018

    • Author(s)
      太田智彦
    • Total Pages
      9
    • Publisher
      乳癌の臨床
    • Data Source
      KAKENHI-PROJECT-16K15712
  • [Book] BRCA1/2の基礎とPARP阻害剤2018

    • Author(s)
      太田智彦
    • Total Pages
      9
    • Publisher
      乳癌の臨床
    • Data Source
      KAKENHI-PROJECT-17H03585
  • [Book] 臨床医のための乳腺基礎医学「乳癌におけるDNA損傷と修復不全」2018

    • Author(s)
      頼勇強, 太田智彦
    • Total Pages
      5
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-26290042
  • [Book] 臨床医のための乳腺基礎医学「乳癌におけるDNA損傷と修復不全」2018

    • Author(s)
      頼勇強, 太田智彦.
    • Total Pages
      5
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-17H03585
  • [Book] 遺伝子診断・遺伝カウンセリング. 遺伝性乳癌卵巣癌症候群(HBOC)診療の手引き 2017年版2017

    • Author(s)
      櫻井晃洋, 赤木究, 和泉美希子, 太田智彦, 三木義男
    • Total Pages
      44
    • Publisher
      金原出版
    • Data Source
      KAKENHI-PROJECT-17H03585
  • [Book] 乳癌学-最新の診断と治療-Ⅲ.乳癌の分子生物学と発症機序「DNA修復不全と乳癌」2017

    • Author(s)
      太田智彦
    • Total Pages
      6
    • Publisher
      日本臨牀
    • Data Source
      KAKENHI-PROJECT-26290042
  • [Book] 乳癌学-最新の診断と治療-Ⅲ.乳癌の分子生物学と発症機序「DNA修復不全と乳癌」2017

    • Author(s)
      太田智彦
    • Total Pages
      6
    • Publisher
      日本臨床
    • Data Source
      KAKENHI-PROJECT-16K15712
  • [Book] 乳癌学-最新の診断と治療- Ⅲ.乳癌の分子生物学と発症機序「DNA修復不全と乳癌2017

    • Author(s)
      太田智彦
    • Total Pages
      6
    • Publisher
      日本臨床
    • Data Source
      KAKENHI-PROJECT-17H03585
  • [Book] 遺伝子診断・遺伝カウンセリング. 遺伝性乳癌卵巣癌症候群(HBOC)診療の手引き 2017年版2017

    • Author(s)
      櫻井晃洋, 赤木究, 和泉美希子, 太田智彦, 三木義男
    • Total Pages
      44
    • Publisher
      金原出版
    • Data Source
      KAKENHI-PROJECT-16K15712
  • [Book] 遺伝子診断・遺伝カウンセリング. 遺伝性乳癌卵巣癌症候群(HBOC)診療の手引き 2017年版2017

    • Author(s)
      櫻井晃洋, 赤木究, 和泉美希子, 太田智彦, 三木義男
    • Total Pages
      44
    • Publisher
      金原出版
    • Data Source
      KAKENHI-PROJECT-26290042
  • [Journal Article] Editorial: Community series in post-translational modifications of proteins in cancer immunity and immunotherapy, volume II2023

    • Author(s)
      Nihira Naoe Taira、Ohta Tomohiko、Liu Zichuan、Dai Xiangpeng
    • Journal Title

      Frontiers in Immunology

      Volume: 14 Pages: 01-03

    • DOI

      10.3389/fimmu.2023.1289016

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K06681, KAKENHI-PROJECT-23K27668
  • [Journal Article] Potential role of Fbxo22 in resistance to endocrine therapy in breast cancer with invasive lobular carcinoma2023

    • Author(s)
      Nakagawa S, Miyashita M, Maeda I, Goda A, Tada H, Amari M, Kojima Y, Tsugawa K, Ohi Y, Sagara Y, Sato M, Ebata A, Shoji NH, Suzuki T, Nakanishi M, Ohta T, Ishida T
    • Journal Title

      Breast Cancer Res Treat.

      Volume: 204 Pages: 453-463

    • DOI

      10.21203/rs.3.rs-3375926/v1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K27668
  • [Journal Article] Alteration of Trop-2 expression in breast cancer cells by clinically used therapeutic agents and acquired tamoxifen resistance2022

    • Author(s)
      Zhu Jing、Wu Wenwen、Togashi Yukiko、Taira Nihira Naoe、Johmura Yoshikazu、Zhu Dajiang、Nakanishi Makoto、Miyoshi Yasuo、Ohta Tomohiko
    • Journal Title

      Breast Cancer

      Volume: 29 Issue: 6 Pages: 1076-1087

    • DOI

      10.1007/s12282-022-01389-3

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03431, KAKENHI-PROJECT-20H03748, KAKENHI-PROJECT-20J40010
  • [Journal Article] Lack of impact of the <scp>ALDH2</scp> rs671 variant on breast cancer development in Japanese <scp>BRCA1</scp> /2‐mutation carriers2022

    • Author(s)
      Mori Tomoharu、Takata Minoru et al.
    • Journal Title

      Cancer Medicine

      Volume: 12 Issue: 6 Pages: 6594-6602

    • DOI

      10.1002/cam4.5430

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K21394, KAKENHI-PROJECT-22K19577, KAKENHI-PROJECT-21K15362, KAKENHI-PROJECT-20H03450, KAKENHI-PROJECT-20H03748
  • [Journal Article] The ZZ domain of HERC2 is a receptor of arginylated substrates2022

    • Author(s)
      Tencer AH, Liu J, Zhu J, Burkholder NT, Zhang Y, Wu W, Strahl BD, Ohta T, Kutateladze TG.
    • Journal Title

      Sci Rep.

      Volume: 12 Issue: 1 Pages: 6063-6063

    • DOI

      10.1038/s41598-022-10119-w

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03748
  • [Journal Article] Molecular targeted drugs resistance impairs double-strand break repair and sensitizes ER-positive breast cancer to PARP inhibitors2021

    • Author(s)
      Suzuki Y, Wu W, Ohta T, Hayashi S
    • Journal Title

      Breast Cancer.

      Volume: 29 Issue: 1 Pages: 77-91

    • DOI

      10.1007/s12282-021-01282-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03748
  • [Journal Article] TP53/p53-FBXO22-TFEB controls basal autophagy to govern hormesis2021

    • Author(s)
      Suzuki Narumi、Johmura Yoshikazu、Wang Teh-Wei、Migita Toshiro、Wu Wenwen、Noguchi Rei、Yamaguchi Kiyoshi、Furukawa Yoichi、Nakamura Shuhei、Miyoshi Ichiro、Yoshimori Tamotsu、Ohta Tomohiko、Nakanishi Makoto
    • Journal Title

      Autophagy

      Volume: 11 Issue: 11 Pages: 1-18

    • DOI

      10.1080/15548627.2021.1897961

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22429, KAKENHI-PROJECT-20K21497, KAKENHI-ORGANIZER-17H06391, KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-19H05740, KAKENHI-PROJECT-20H03748, KAKENHI-PUBLICLY-20H04940, KAKENHI-PROJECT-19H03431, KAKENHI-PROJECT-20J13207, KAKENHI-PROJECT-20K07563
  • [Journal Article] RNF168 E3 ligase participates in ubiquitin signaling and recruitment of SLX4 during DNA crosslink repair2021

    • Author(s)
      Katsuki Yoko、Abe Masako、Park Seon Young、Wu Wenwen、Yabe Hiromasa、Yabe Miharu、van Attikum Haico、Nakada Shinichiro、Ohta Tomohiko、Seidman Michael M.、Kim Yonghwan、Takata Minoru
    • Journal Title

      Cell Reports

      Volume: 37 Issue: 4 Pages: 109879-109879

    • DOI

      10.1016/j.celrep.2021.109879

    • NAID

      120007165816

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03450, KAKENHI-PROJECT-20H03748, KAKENHI-PROJECT-20K12161, KAKENHI-PROJECT-20K21394
  • [Journal Article] HERC2 inactivation abrogates nucleolar localization of RecQ helicases BLM and WRN2021

    • Author(s)
      Zhu M, Wu W, Togashi Y, Liang W, Miyoshi Y, Ohta T
    • Journal Title

      Sci Rep.

      Volume: 11 Issue: 1 Pages: 360-360

    • DOI

      10.1038/s41598-020-79715-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03748
  • [Journal Article] Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast2021

    • Author(s)
      Satoi Nagasawa, Yuta Kuze, Ichiro Maeda, Yasuyuki Kojima, Ai Motoyoshi, Tatsuya Onishi, Hibiki Seino, Ayako Suzuki, Masahide Seki, Eisuke Inoue, Koichiro Tsugawa, Tomohiko Ohta, Yutaka Suzuki, et al.
    • Journal Title

      Communications Biology

      Volume: 4 Issue: 1

    • DOI

      10.1038/s42003-021-01959-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-20H03748
  • [Journal Article] FBXO22, an epigenetic multiplayer coordinating senescence, hormone signaling, and metastasis2020

    • Author(s)
      Johmura Yoshikazu、Harris Alexander S.、Ohta Tomohiko、Nakanishi Makoto
    • Journal Title

      Cancer Science

      Volume: 111 Issue: 8 Pages: 2718-2725

    • DOI

      10.1111/cas.14534

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K21497, KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-19H05740, KAKENHI-PROJECT-20H03748
  • [Journal Article] HERC2 regulates RPA2 by mediating ATR-induced Ser33 phosphorylation and ubiquitin-dependent degradation.2019

    • Author(s)
      Lai Y, Zhu M, Wu W, Rokutanda N, Togashi Y, Liang W, Ohta T.
    • Journal Title

      Sci Rep.

      Volume: 9 Issue: 1 Pages: 14257-14257

    • DOI

      10.1038/s41598-019-50812-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08676, KAKENHI-PROJECT-17H03585
  • [Journal Article] Fbxo22-mediated KDM4B degradation determines selective estrogen receptor modulator activity in breast cancer.2018

    • Author(s)
      Johmura Y, Maeda I, Suzuki N, Wu W, Goda A,Morita M, Yamaguchi K, Yamamoto M, Nagasawa S, Kojima Y, Tsugawa K, Inoue N, Miyoshi Y, Osako T Akiyama F, Maruyama R, Inoue JI, Fukukawa Y, Ohta T, Nkanishi M.
    • Journal Title

      J Clin Invest.

      Volume: 128 Issue: 12 Pages: 5603-5619

    • DOI

      10.1172/jci121679

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08676, KAKENHI-PROJECT-18K15235, KAKENHI-PLANNED-16H06575, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05026, KAKENHI-PROJECT-17H03575, KAKENHI-PROJECT-17H03585, KAKENHI-PROJECT-16H06148, KAKENHI-PROJECT-16K15238, KAKENHI-PROJECT-17K18336, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17H01398, KAKENHI-PROJECT-17K07214
  • [Journal Article] HERC2 facilitates BLM and WRN helicase complex interaction with RPA to suppress G-quadruplex DNA.2018

    • Author(s)
      Wu W, Rokutanda N, Takeuchi J, Lai Y, Maruyama R, Togashi Y, Nishikawa H, Arai N, Miyoshi Y,Suzuki N, Saeki Y, Tanaka K, Ohta T.
    • Journal Title

      Cancer Res.

      Volume: 78 Issue: 22 Pages: 6371-6385

    • DOI

      10.1158/0008-5472.can-18-1877

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08676, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PROJECT-18H03993, KAKENHI-PROJECT-17H03585, KAKENHI-PROJECT-17K18336
  • [Journal Article] Chromatin Regulation by HP1γ Contributes to Survival of 5-Azacytidine-Resistant Cells.2018

    • Author(s)
      Imanishi S, Umezu T, Kobayashi C, Ohta T, Ohyashiki K, Ohyashiki JH.
    • Journal Title

      Front Pharmacol.

      Volume: 9 Pages: 1166-1166

    • DOI

      10.3389/fphar.2018.01166

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07244, KAKENHI-PROJECT-17H03585, KAKENHI-PROJECT-16K07183, KAKENHI-PROJECT-17K15656
  • [Journal Article] HP1 regulates the localization of FANCJ at sites of DNA double-strand breaks.2016

    • Author(s)
      Wu W, Togashi Y, Johmura Y, Miyoshi Y, Nobuoka S, Nakanishi M, Ohta T.
    • Journal Title

      Cancer Sci.

      Volume: 107 Issue: 10 Pages: 1406-1415

    • DOI

      10.1111/cas.13008

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-24112005, KAKENHI-PROJECT-16H06148, KAKENHI-PROJECT-26460402, KAKENHI-PROJECT-16K15238, KAKENHI-PROJECT-16K15712, KAKENHI-PROJECT-16K15239, KAKENHI-PROJECT-26290042, KAKENHI-PROJECT-26250027
  • [Journal Article] 癌の発症と治療におけるユビキチン系の役割2016

    • Author(s)
      扇屋りん, 太田智彦
    • Journal Title

      医学のあゆみ

      Volume: 256 Pages: 868-873

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-24112005
  • [Journal Article] Functional Link between BRCA1 and BAP1 through Histone H2A, Heterochromatin and DNA Damage Response.2016

    • Author(s)
      Fukuda T, Tsuruga T, Kuroda T, Nishikawa H, Ohta T.
    • Journal Title

      Curr Cancer Drug Targets.

      Volume: 16(2) Issue: 2 Pages: 101-9

    • DOI

      10.2174/1568009615666151030102427

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461962, KAKENHI-PLANNED-24112005, KAKENHI-PROJECT-26670730, KAKENHI-PROJECT-26290042
  • [Journal Article] 癌の発症と治療におけるユビキチン系の役割2016

    • Author(s)
      扇屋りん, 太田智彦
    • Journal Title

      医学のあゆみ

      Volume: 256 Pages: 868-873

    • Data Source
      KAKENHI-PROJECT-26670730
  • [Journal Article] 癌の発症と治療におけるユビキチン系の役割2016

    • Author(s)
      扇屋りん, 太田智彦
    • Journal Title

      医学のあゆみ

      Volume: 256 Pages: 868-873

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26290042
  • [Journal Article] Interaction of BARD1 and HP1 Is Required for BRCA1 Retention at Sites of DNA Damage.2015

    • Author(s)
      Wu W, Nishikawa H, Fukuda T, Vittal V, Asano M, Miyoshi Y, Klevit RE, Ohta T
    • Journal Title

      Cancer Res

      Volume: 75 Issue: 7 Pages: 1311-1321

    • DOI

      10.1158/0008-5472.can-14-2796

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460402, KAKENHI-PLANNED-24112005, KAKENHI-PROJECT-26670730, KAKENHI-PROJECT-25290031, KAKENHI-PROJECT-26290042
  • [Journal Article] Class I HDAC inhibitors inhibit the retention of BRCA1 and 53BP1 at the site of DNA damage2015

    • Author(s)
      Fukuda T,Wu W, Okada M,Maeda I, Kojima Y, Hayami R, Miyoshi Y, Tsugawa K, Ohta T
    • Journal Title

      Cancer Science

      Volume: 106 Issue: 8 Pages: 1050-1056

    • DOI

      10.1111/cas.12717

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460402, KAKENHI-PLANNED-24112005, KAKENHI-PUBLICLY-26102741, KAKENHI-PROJECT-26670730, KAKENHI-PROJECT-26290042
  • [Journal Article] Interaction of BARD1 and HP1 is required for BRCA1 retention at sites of DNA damage.2015

    • Author(s)
      Wu W, Nishikawa H, Fukuda T, Vittal V, Asano M, Miyoshi Y, Klevit RE, Ohta T.
    • Journal Title

      Cancer Res.

      Volume: 75 Pages: 1311-1321

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670730
  • [Journal Article] Ubiquitin acetylation inhibits polyubiquitin chain elongation.2015

    • Author(s)
      Ohtake F, Saeki Y, Sakamoto K, Ohtake K, Nishikawa H, Tsuchiya H, Ohta T, Tanaka K, Kanno J.
    • Journal Title

      EMBO Rep.

      Volume: 16 Issue: 2 Pages: 192-201

    • DOI

      10.15252/embr.201439152

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-24112005, KAKENHI-PLANNED-24112008, KAKENHI-PROJECT-26290042, KAKENHI-PROJECT-26291035, KAKENHI-PROJECT-26670730, KAKENHI-PROJECT-26870853, KAKENHI-PLANNED-24112004, KAKENHI-PROJECT-26000014
  • [Journal Article] Interaction of BARD1 and HP1 is required for BRCA1 retention at sites of DNA damage.2015

    • Author(s)
      Wu W, Nishikawa H, Fukuda T, Vittal V, Asano M, Miyoshi Y, Klevit RE, Ohta T.
    • Journal Title

      Cancer Res.

      Volume: 75 Pages: 1311-1321

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26290042
  • [Journal Article] LSD1 Overexpression Is Associated with Poor Prognosis in Basal-Like Breast Cancer, and Sensitivity to PARP Inhibition.2015

    • Author(s)
      Nagasawa S, Sedukhina AS, Nakagawa Y, Maeda I, Kubota M, Ohnuma S, Tsugawa K, Ohta T, Roche-Molina M, Bernal JA, Narváez AJ, Jeyasekharan AD, Sato K.
    • Journal Title

      PLoS One.

      Volume: 10 Issue: 2 Pages: e0118002-e0118002

    • DOI

      10.1371/journal.pone.0118002

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-24112005, KAKENHI-PROJECT-26290042, KAKENHI-PROJECT-26670730
  • [Journal Article] NF-kB signaling mediates acquired resistance after PARP inhibition.2015

    • Author(s)
      Nakagawa Y, Sedukhina AS, Okamoto N, Nagasawa S, Suzuki N, Ohta T, Hattori H, Roche-Molina M, Narváez AJ, Jeyasekharan AD, Bernal JA, Sato K.
    • Journal Title

      Oncotarget.

      Volume: 6 Pages: 3825-3539

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-24112005
  • [Journal Article] MED12 exon 2 mutations in phyllodes tumors of the breast2015

    • Author(s)
      Nagasawa S, Maeda I, Fukuda T, Wu W, Hayami R, Kojima Y, Tsugawa KI, Ohta T
    • Journal Title

      Cancer Med

      Volume: Epub ahead of print Issue: 7 Pages: 1-5

    • DOI

      10.1002/cam4.462

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460402, KAKENHI-PLANNED-24112005, KAKENHI-PROJECT-26670730, KAKENHI-PROJECT-26290042
  • [Journal Article] Liganded ERα stimulates the E3 ubiquitin ligase activity of UBE3C to facilitate cell proliferation2015

    • Author(s)
      Okada M, Ohtake F, Nishikawa H, Wu W, Saeki Y, Takana K, Ohta T
    • Journal Title

      Molecular Endocrinology

      Volume: 29 Issue: 11 Pages: 1646-1657

    • DOI

      10.1210/me.2015-1125

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460402, KAKENHI-PLANNED-24112005, KAKENHI-PLANNED-24112008, KAKENHI-PUBLICLY-26102741, KAKENHI-PROJECT-26670730, KAKENHI-PROJECT-26290042, KAKENHI-PROJECT-26000014
  • [Journal Article] NF-kB signaling mediates acquired resistance after PARP inhibition.2015

    • Author(s)
      Nakagawa Y, Sedukhina AS, Okamoto N, Nagasawa S, Suzuki N, Ohta T, Hattori H, Roche-Molina M, Narváez AJ, Jeyasekharan AD, Bernal JA, Sato K.
    • Journal Title

      Oncotarget.

      Volume: 6 Pages: 3825-3839

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670730
  • [Journal Article] The BARD1/HP1 interaction: another clue about heterochromatin involvement in homologous recombination2015

    • Author(s)
      Fukuda T, Tsuruga T, Kuroda T, Takeuchi J, Wu W, Ohta T
    • Journal Title

      Molecular & Cellular Oncology

      Volume: aEpub ahead of print Issue: 2 Pages: 1-3

    • DOI

      10.1080/23723556.2015.1030535

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460402, KAKENHI-PLANNED-24112005, KAKENHI-PROJECT-26670730, KAKENHI-PROJECT-26290042
  • [Journal Article] Interaction of BARD1 and HP1 is required for BRCA1 retention at sites of DNA damage.2015

    • Author(s)
      Wu W, Nishikawa H, Fukuda T, Vittal V, Asano M, Miyoshi Y, Klevit RE, Ohta T.
    • Journal Title

      Cancer Res.

      Volume: 75 Pages: 1311-1321

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-24112005
  • [Journal Article] NF-kB signaling mediates acquired resistance after PARP inhibition.2015

    • Author(s)
      Nakagawa Y, Sedukhina AS, Okamoto N, Nagasawa S, Suzuki N, Ohta T, Hattori H, Roche-Molina M, Narváez AJ, Jeyasekharan AD, Bernal JA, Sato K.
    • Journal Title

      Oncotarget.

      Volume: 6 Pages: 3825-3539

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26290042
  • [Journal Article] Aberrant DNA methylation status of DNA repair genes in breast cancer treated with neoadjuvant chemotherapy2013

    • Author(s)
      Watanabe Y, Maeda I, Oikawa R, Wu W, Tsuchiya K, Miyoshi Y, Itoh F, Tsugawa K, Ohta T
    • Journal Title

      Genes to Cells

      Volume: 18(12) Issue: 12 Pages: 1120-1130

    • DOI

      10.1111/gtc.12100

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300358, KAKENHI-PROJECT-23590348, KAKENHI-PLANNED-24112005
  • [Journal Article] A DNA-Damage Selective Role for BRCA1 E3 Ligase in Claspin Ubiquitylation, CHK1 Activation, and DNA Repair2012

    • Author(s)
      Sato K, Sundaramoorthy E, Rajendra E, Hattori H, Jeyasekharan AD, Ayoub N, Schiess R, Aebersold R, Nishikawa H, Sedukhina AS, Wada H, Ohta T, Venkitaraman AR
    • Journal Title

      Curr Biol

      Volume: 22 Issue: 18 Pages: 1659-66

    • DOI

      10.1016/j.cub.2012.07.034

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300358, KAKENHI-PROJECT-24591568, KAKENHI-PLANNED-24112005
  • [Journal Article] DNA相同組換え修復と乳癌2012

    • Author(s)
      太田智彦
    • Journal Title

      Medical Science Digest

      Volume: 38 Pages: 637-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-23131514
  • [Journal Article] 乳癌治療におけるユビキチン修飾2012

    • Author(s)
      佐藤 工, 太田 智彦
    • Journal Title

      医学のあゆみ

      Volume: 243(6) Pages: 520-524

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300358
  • [Journal Article] BRCA1とDNA損傷応答2012

    • Author(s)
      セドキーナ アンナ, 福田 貴代, 太田智彦
    • Journal Title

      生化学

      Volume: 84(7) Pages: 637-640

    • NAID

      10030966547

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300358
  • [Journal Article] DNA相同組換え修復と乳癌2012

    • Author(s)
      太田智彦
    • Journal Title

      Medical Science Digest

      Volume: 38 Pages: 637-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300358
  • [Journal Article] DNA 相同組換え修復と乳癌2012

    • Author(s)
      太田 智彦, 西川 裕之
    • Journal Title

      Medical Science Digest

      Volume: 38(1) Pages: 637-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300358
  • [Journal Article] 乳癌-基礎と臨床の最新研究動向-」III乳癌の分子生物学と発癌機序1. 分子生物学 (2)癌遺伝子と癌抑制遺伝子2012

    • Author(s)
      福田 貴代, セドキーナ アンナ, 太田智彦
    • Journal Title

      日本臨牀 : 増刊号「乳癌」

      Volume: 9 Pages: 66-70

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300358
  • [Journal Article] The BRCA1 ubiquitin ligase and homologous recombination repair2011

    • Author(s)
      Ohta T
    • Journal Title

      FEBS Lett

      Volume: 585 Issue: 18 Pages: 2836-44

    • DOI

      10.1016/j.febslet.2011.05.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-23131514, KAKENHI-PROJECT-23300358
  • [Journal Article] HERC2 Interacts with Claspin and regulates DNA origin firingandr eplication fork progression2011

    • Author(s)
      Izawa N, Wu W, Sato K, Nishikawa H, Kato A, Boku N, Itoh F, Ohta T
    • Journal Title

      Cancer Research

      Volume: Volume 71 Issue: 17 Pages: 5621-5625

    • DOI

      10.1158/0008-5472.can-11-0385

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22710053, KAKENHI-PUBLICLY-23131514, KAKENHI-PROJECT-23300358, KAKENHI-PROJECT-23590348
  • [Journal Article] DNA損傷応答と乳癌の薬剤感受性2010

    • Author(s)
      太田智彦,小泉宏隆,呉文文
    • Journal Title

      乳癌の臨床2010年(篠原出版新社) 第25巻、第6号

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Journal Article] BRCA遺伝子異常と標的治療2010

    • Author(s)
      太田智彦
    • Journal Title

      がん分子標的治療

      Volume: 8 Pages: 46-52

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21025032
  • [Journal Article] 「乳がん」、遺伝子診療学(第2版)-遺伝子診断の進歩とゲノム治療の展望-2010

    • Author(s)
      太田智彦
    • Journal Title

      日本臨床 984巻、8号

      Pages: 438-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Journal Article] BRCA遺伝子異常と標的治療2010

    • Author(s)
      太田智彦
    • Journal Title

      がん分子標的治療 (In press)

    • Data Source
      KAKENHI-PROJECT-20058036
  • [Journal Article] がんのゲノム解析と診療への応用 a)乳がん2010

    • Author(s)
      太田智彦
    • Journal Title

      日本臨牀 (In press)

    • Data Source
      KAKENHI-PROJECT-20591557
  • [Journal Article] Recruitment of phosphorylated NPM1 to sites of DNA damage through RNF8-dependent ubiquitin conjugates.2010

    • Author(s)
      Koike A, Nishikawa H, Wu W, Okada Y, Venkitaraman AR, Ohta T.
    • Journal Title

      Cancer Res. 70(17)

      Pages: 6746-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Journal Article] Prediction of breast cancer sensitivity to neoadjuvant chemotherapy based on status of DNA damage repair proteins.2010

    • Author(s)
      Asakawa H, Koizumi H, Koike A, Takahashi M, Wu W, Iwase H, Fukuda M, Ohta T.
    • Journal Title

      Breast Cancer Res. 12(2)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Journal Article] がんのゲノム解析と診療への応用a)乳がん2010

    • Author(s)
      太田智彦
    • Journal Title

      日本臨林 (In press)

    • Data Source
      KAKENHI-PROJECT-20058036
  • [Journal Article] BRCA遺伝子異常と標的治療2010

    • Author(s)
      太田智彦
    • Journal Title

      がん分子標的治療 (In press)

    • Data Source
      KAKENHI-PROJECT-20591557
  • [Journal Article] Clinicopathological analyses of triple negative breast cancer using surveillance data from the Registration Committee of the Japanese Breast Cancer Society.2010

    • Author(s)
      Iwase H, Kurebayashi J, Tsuda H, Ohta T, Kurosumi M, Miyamoto K, Yamamoto Y, Iwase T
    • Journal Title

      Breast Cancer. 17(2)

      Pages: 118-24

    • NAID

      10027255494

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Journal Article] がんのゲノム解析と診療への応用a)乳がん2010

    • Author(s)
      太田智彦
    • Journal Title

      日本臨牀 (In press)

    • Data Source
      KAKENHI-PUBLICLY-21025032
  • [Journal Article] 乳がん2010

    • Author(s)
      太田智彦
    • Journal Title

      日本臨牀 遺伝子診療学(第2版)

      Volume: 984 Pages: 438-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Journal Article] Venkitaraman AR. A mitotic role for the DNA damage-responsive CHK2 kinase.2010

    • Author(s)
      Sato K, Ohta T
    • Journal Title

      Nat Cell Biol. 12(5)

      Pages: 424-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Journal Article] HERC2 is an E3 ligase that targets BRCA1 for degradation.2010

    • Author(s)
      Wu W, Sato K, Koike A, Nishikawa H, Koizumi H, Venkitaraman AR, Ohta T.
    • Journal Title

      Cancer Res. 70(15)

      Pages: 6384-92

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Journal Article] BRCA遺伝子異常と標的治療2010

    • Author(s)
      太田智彦
    • Journal Title

      がん分子標的治療(メディカルレビュー社) Vol.8 No.2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Journal Article] 乳がん2010

    • Author(s)
      太田智彦
    • Journal Title

      日本臨林 遺伝子診療学(第2版)

      Volume: 984 Pages: 438-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21025032
  • [Journal Article] Hoxb4 transduction down-regulates Geminin protein, providing hematopoietic stem and progenitor cells with proliferation potential.2010

    • Author(s)
      Ohno Y, Yasunaga S, Ohtsubo M, Mori S, Tsumura M, Okada S, Ohta T, Ohtani K, Kobayashi M, Takihara Y
    • Journal Title

      Proc Natl Acad Sci U S A. 107(50)

      Pages: 21529-34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Journal Article] DNA損傷応答と乳癌の薬剤感受性2010

    • Author(s)
      太田智彦
    • Journal Title

      乳癌の臨床

      Volume: 25 Pages: 609-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21025032
  • [Journal Article] DNA損傷応答と乳癌の薬剤感受性2010

    • Author(s)
      太田智彦
    • Journal Title

      乳癌の臨床

      Volume: 25 Pages: 609-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Journal Article] BRCA遺伝子異常と標的治療2010

    • Author(s)
      太田智彦
    • Journal Title

      がん分子標的治療

      Volume: 8 Pages: 46-52

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Journal Article] BRCA遺伝子異常と標的治療2010

    • Author(s)
      太田智彦
    • Journal Title

      がん分子標的治療 (In press)

    • Data Source
      KAKENHI-PUBLICLY-21025032
  • [Journal Article] Perturbation of DNA repair pathways by proteasome inhibitors corresponds to enhanced chemosensitivity of cells to DNA damage-inducing agents.2009

    • Author(s)
      Takeshita T, Wu W, Koike A, Fukuda M, Ohta T.
    • Journal Title

      Cancer Chemother. Pharmacol. 64

      Pages: 1039-46

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Journal Article] Contemplating chemosensitivity of basal-like breast cancer based on BRCA1 dysfunction.2009

    • Author(s)
      Tomohiko Ohta
    • Journal Title

      Breast Cancer 16

      Pages: 268-74

    • NAID

      10027254733

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21025032
  • [Journal Article] BAP1 interferes with BRCA1/BARD1 RING heterodimer activity.2009

    • Author(s)
      Nishikawa H, Wu W, Koike A, Kojima R, Gomi H, Fukuda M, Ohta T.
    • Journal Title

      Cancer Res. 69

      Pages: 111-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Journal Article] Contemplating chemosensitivity of basal-like breast cancer based on BRCA1 dysfunction.2009

    • Author(s)
      Tomohiko Ohta
    • Journal Title

      Breast Cance 16

      Pages: 268-74

    • NAID

      10027254733

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20058036
  • [Journal Article] Contemplating chemosensitivity of basal-like breast cancer based on BRCA1 dysfunction.2009

    • Author(s)
      Tomohiko Ohta
    • Journal Title

      Breast Cancer 16

      Pages: 268-74

    • NAID

      10027254733

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Journal Article] Contemplating chemosensitivity of basal-like breast cancer based on BRCA1 dysfunction2009

    • Author(s)
      Tomohiko Ohta
    • Journal Title

      Breast Cancer (In press)

    • NAID

      10027254733

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20058036
  • [Journal Article] Contemplating chemosensitivity of basal-like breast cancer based on BRCA1 dysfunction.2009

    • Author(s)
      Ohta T, Wu W, Koike A, Asakawa H, Koizumi H, Fukuda M
    • Journal Title

      Breast Cancer. 16(4)

      Pages: 268-74

    • NAID

      10027254733

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Journal Article] Contemplating chemosensitivity of basal-like breast cancer based on BRCAl dysfunction2009

    • Author(s)
      Tomohiko Ohta
    • Journal Title

      Breast Cancer (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Journal Article] The ubiquitin E3 ligase activity of BRCA1 and its biological functions.2008

    • Author(s)
      Wu W, Koike A, Takeshita T, Ohta T.
    • Journal Title

      Cell Div. Jan 7

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Journal Article] Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis.2008

    • Author(s)
      Shimo A, Tanikawa C, Nishidate T, Lin ML, Matsuda K, Park JH, Ueki T, Ohta T, Hirata K, Fukuda M, Nakamura Y, Katagiri T
    • Journal Title

      Cancer Sci. 99

      Pages: 62-70

    • NAID

      10024000927

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Journal Article] Contemplating chemosensitivity of basal-like breast cancer based on BRCAI dysfunction2008

    • Author(s)
      Tomohiko Ohta
    • Journal Title

      Breast Cancer (In press)(Open amass)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19044042
  • [Journal Article] Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis.2008

    • Author(s)
      Shimo A, Tanikawa C, Nishidate T, Lin ML, Matsuda K, Park JH, Ueki T, Ohta T, Hirata K, Fukuda M, Nakamura Y, Katagiri T.
    • Journal Title

      Cancer Sci. 99(1)

      Pages: 62-70

    • NAID

      10024000927

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591486
  • [Journal Article] The ubiquitin E3 ligase activity of BRCA1 and its biological functions.2008

    • Author(s)
      Wu W, Koike A, Takeshita T, Ohta T.
    • Journal Title

      Cell Div. 3:1

      Pages: 1-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Journal Article] Modification of the hepatic mitochondrial proteome in response to ischemic preconditioning following ischemia-reperfusion injury of the rat liver.2008

    • Author(s)
      Oshima R, Nakano H, Katayama M, Sakurai J, Wu W, Koizumi S, Asano T, Watanabe T, Asakura T, Ohta T, Otsubo T
    • Journal Title

      Eur Surg Res. 40

      Pages: 247-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Journal Article] The ubiquitin E3 ligase activity of BRCA1 and its biological functions.2008

    • Author(s)
      Wu W, Koike A, Takeshita T, Ohta T.
    • Journal Title

      Cell Div. Jan 7

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591486
  • [Journal Article] Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis.2008

    • Author(s)
      Shimo A, Tanikawa C, Nishidate T, Lin ML, Matsuda K, Park JH, Ueki T, Ohta T, Hirata K, Fukuda M, Nakamura Y, Katagiri T.
    • Journal Title

      Cancer Sci. 99(1)

      Pages: 62-70

    • NAID

      10024000927

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Journal Article] The UPS : A promising target for breast cancer treatment.2008

    • Author(s)
      Sato K, Rajendra E, Ohta T.
    • Journal Title

      BMC Biochem. 9(suppl 1):S2

      Pages: 1-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Journal Article] 「研究成果報告書概要(欧文)」より2007

    • Author(s)
      Yamasaki S, Yagishita N, Sasaki T, Nakazawa M, Kato Y, Yamadera T, Bae E, Toriyama S, Ikeda R, Zhang L, Fujitani K, Yoo E, Tsuchimochi K, Ohta T, Araya N, Fujita H, Aratani S, Eguchi K, Komiya S, Maruyama I, Higashi N, Sato M, Senoo H, Ochi T, Yokoyama S, Amano T, Kim J, Gay S, Fukamizu A, Nishioka K, Tanaka K, Nakajima T.
    • Journal Title

      EMBO J. 26

      Pages: 113-22

    • Data Source
      KAKENHI-PROJECT-18591446
  • [Journal Article] Predictive markers in breast cancer treatment-focusing on a recent topicbasal-like breast cancer2007

    • Author(s)
      Koike A, Ohta T.
    • Journal Title

      Nippon Rinsho.(Suppl 6) 65

      Pages: 285-90

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591486
  • [Journal Article] BRCA1 ubiquitinates RPB8 in response to DNA damage.2007

    • Author(s)
      Wu W, Nishikawa H, Hayami R, Sato K, Honda A, Aratani S, Nakajima T, Fukuda M, Ohta T.
    • Journal Title

      Cancer Res. 67(3)

      Pages: 951-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591486
  • [Journal Article] BECA1 ubiquitinates RPB8 in response to DNA damage.2007

    • Author(s)
      Ohta T, et al.
    • Journal Title

      Cancer Res. 67(3)

    • Data Source
      KAKENHI-PROJECT-18591486
  • [Journal Article] Predictive markers in breast cancer treatment-focusing on a recent topic "basal-like breast cancer"2007

    • Author(s)
      Ohta T, et. al.
    • Journal Title

      Nippon Rinsho 65Suppl6

      Pages: 285-90

    • NAID

      40015531685

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591486
  • [Journal Article] BRCA1 ubiquitinates RPB8 in response to DNA damage.2007

    • Author(s)
      Wu W, Nishikawa H, Hayami R, Sato K, Honda A, Aratani S, Nakajima T, Fukuda M, Ohta T.
    • Journal Title

      Cancer Res. 67(3)

      Pages: 951-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Journal Article] Modification of the Hepatic Mitochondrial Proteome in Response to Ischemic Preconditioning following Ischemia-Reperfusion Injury of the Rat Liver.2007

    • Author(s)
      Oshima R, Nakano H, Katayama M, Sakurai J, Wu W, Koizumi S, Asano T, Watanabe T, Asakura T, Ohta T, Otsubo T.
    • Journal Title

      Eur Surg Res. 40(3)

      Pages: 247-255

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Journal Article] Putative tumor suppressor EDD interacts with and up-regulates APC.2007

    • Author(s)
      Ohshima R, Ohta T, Wu W, Koike A, Iwatani T, Henderson M, Watts CK, Otsubo T.
    • Journal Title

      Genes Cells. 12(12)

      Pages: 1339-45

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Journal Article] Predictive markers in breast cancer treatment-focusing on a recent topicbasal-like breast cancer2007

    • Author(s)
      Koike A, Ohta T.
    • Journal Title

      Nippon Rinsho.(Suppl 6) 65

      Pages: 285-90

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Journal Article] Putative tumor suppressor EDD interacts with and up-regulates APC.2007

    • Author(s)
      Ohshima R, Ohta T, Wu W, Koike A, Iwatani T, Henderson M, Watts CK, Otsubo T.
    • Journal Title

      Genes Cells. 12(12)

      Pages: 1339-45

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591486
  • [Journal Article] Elevated expression of PRC1,involved in the growth of breast cancer cells.2007

    • Author(s)
      Ohta T, er al
    • Journal Title

      Cancer Sci. 98

      Pages: 174-81

    • Data Source
      KAKENHI-PROJECT-18591486
  • [Journal Article] Putative tumor suppressor EDD interacts with and up-regulates APC.2007

    • Author(s)
      Ohta, T, et. al.
    • Journal Title

      Genes Cells 12

      Pages: 1339-45

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591486
  • [Journal Article] Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase'Synoviolin'.2007

    • Author(s)
      Yamasaki S, Yagishita N, Sasaki T, Nakazawa M, Kato Y, Yamadera T, Bae E, Toriyama S, Ikeda R, Zhang L, Fujitani K, Yoo E, Tsuchimochi K, Ohta T, Araya N, Fujita H, Aratani S, Eguchi K, Komiya S, Maruyama I, Higashi N, Sato M, Senoo H, Ochi T, Yokoyama S, Amano T, Kim J, Gay S, Fukamizu A, Nishioka K, Tanaka K, Nakajima T.
    • Journal Title

      EMBO J. 26

      Pages: 113-22

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591486
  • [Journal Article] Modification of the Hepatic Mitochondrial Proteome in Response to Ischemic Preconditioning following Ischemia-Reperfusion Injury of the Rat Liver.2007

    • Author(s)
      Oshima R, Nakano H, Katayama M, Sakurai J, Wu W, Koizumi S, Asano T, Watanabe T, Asakura T, Ohta T, Otsubo T.
    • Journal Title

      Eur Surg Res. 40(3)

      Pages: 247-255

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591486
  • [Journal Article] Breast and ovarian cancer susceptibility product BRCA12007

    • Author(s)
      Ohta T.
    • Journal Title

      Protein Nucleic Acid and Enzyme (PNE) 51

      Pages: 1395-1400

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591486
  • [Journal Article] Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'Synoviolin'.2007

    • Author(s)
      Ohta T, er al
    • Journal Title

      EMBO J. 26

      Pages: 113-22

    • Data Source
      KAKENHI-PROJECT-18591486
  • [Journal Article] Modification of the Hepatic Mitochondrial Proteome in Response to Ischemic Preconditioning following Ischemia-Reperfusion Injury of the Rat Liver.2007

    • Author(s)
      Ohta T, et. al.
    • Journal Title

      Eur Surg Res 40(3)

      Pages: 247-255

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591486
  • [Journal Article] Elevated expression of PRC1, involved in the growth of breast cancer ells.2007

    • Author(s)
      Shimo A, Nishidate T, Ohta T, Fukuda M, Nakamura Y, Katagiri T.
    • Journal Title

      Cancer Sci. 98

      Pages: 174-81

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591486
  • [Journal Article] Elevated expression of PRC1, involved in the growth of breast cancer cells.2007

    • Author(s)
      Shimo A, Nishidate T, Ohta T, Fukuda M, Nakamura Y, Katagiri T.
    • Journal Title

      Cancer Sci. 98

      Pages: 174-81

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Journal Article] 乳癌および卵巣癌抑制遺伝子BRCA12006

    • Author(s)
      太田智彦, ほか
    • Journal Title

      PNE : 蛋白核酸酵素 51

      Pages: 1395-1400

    • Data Source
      KAKENHI-PROJECT-18591486
  • [Journal Article] Breast and ovarian cancer susceptibility product BRCA1.2006

    • Author(s)
      Ohta T.
    • Journal Title

      Protein Nucleic Acid and Enzyme(PNE) 51

      Pages: 1395-1400

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Journal Article] Breast and ovarian cancer susceptibility product BRCA1.2006

    • Author(s)
      Ohta T.
    • Journal Title

      Protein Nucleic Acid and Enzyme(PNE) 51

      Pages: 1395-1400

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591486
  • [Journal Article] 乳癌および卵巣癌抑制遺伝子BRCA12006

    • Author(s)
      太田 智彦
    • Journal Title

      PNE:蛋白核酸酵素 51

      Pages: 1395-1400

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Journal Article] 乳癌および卵巣癌抑制遺伝子BRCA12006

    • Author(s)
      太田智彦
    • Journal Title

      PNE : 蛋白核酸酵素 51(10 suppl)

      Pages: 1395-1400

    • Data Source
      KAKENHI-PROJECT-18591446
  • [Journal Article] A truncated splice variant of human BARD1 that lacks the RING finger and ankyrin repeats.2006

    • Author(s)
      Tsuzuki M, Wu W, Nishikawa H, Hayami R, Oyake D, Yabuki Y, Fukuda M, Ohta T.
    • Journal Title

      Cancer Lett. 233(1)

      Pages: 108-116

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591280
  • [Journal Article] A FancD2-monoubiquitin fusion reveals hidden functions of Fanconi anemia core complex in DNA repair.2005

    • Author(s)
      Matsushita N, Kitao H, Ishiai M, Nagashima N, Hirano S, Okawa K, Ohta T, Yu DS, McHugh PJ, Hickson ID, Venkitaraman AR, Kurumizaka H, Takata M.
    • Journal Title

      Mol Cell. 19(6)

      Pages: 841-847

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591280
  • [Journal Article] Down-regulation of BRCA1-BARD1 ubiquitin ligase by CDK2.2005

    • Author(s)
      Hayami R, Sato K, Wu W, Nishikawa T, Hiroi J, Ohtani-Kaneko R, Fukuda M, Ohta T.
    • Journal Title

      Cancer Res. 65(1)

      Pages: 6-10

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591280
  • [Journal Article] 乳がん抑制遺伝子BRCA12004

    • Author(s)
      太田智彦
    • Journal Title

      現代医療 36(4)

      Pages: 167-172

    • Data Source
      KAKENHI-PROJECT-16026243
  • [Journal Article] BRCA1ユビキチンリガーゼと乳癌2004

    • Author(s)
      太田智彦
    • Journal Title

      医学のあゆみ 211(1)

      Pages: 49-53

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591280
  • [Journal Article] Breast tumor suppressor BRCA12004

    • Author(s)
      Ohta T, Hayami R, Wu W, Fukuda M.
    • Journal Title

      New Horizon Med. (Japanese) 36(4)

      Pages: 167-173

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591280
  • [Journal Article] 乳がん抑制遺伝子BRCA12004

    • Author(s)
      太田智彦
    • Journal Title

      現代医療 36(4)

      Pages: 167-172

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591280
  • [Journal Article] Nucleophosmin/B23 is a candidate substrate for the BRCA1-BARD1 ubiquitin ligase.2004

    • Author(s)
      Sato K, Hayami R, Wu W, Nishikawa T, Nishikawa H, Okuda Y, Ogata H, Fukuda M, Ohta T.
    • Journal Title

      J.Biol.Chem. 279(30)

      Pages: 30919-30922

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591280
  • [Journal Article] BRCA1ユビキチンリガーゼと乳癌2004

    • Author(s)
      太田智彦
    • Journal Title

      医学のあゆみ 211(1)

      Pages: 49-53

    • Data Source
      KAKENHI-PROJECT-16026243
  • [Journal Article] BRCA1 ubiquitin ligase and breast cancer2004

    • Author(s)
      Ohta T, Fukuda M.
    • Journal Title

      J.Clin Exp.Med. (Japanese) 211(1)

      Pages: 49-53

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591280
  • [Journal Article] Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage.2004

    • Author(s)
      Hu J, McCall CM, Ohta T, Xiong Y.
    • Journal Title

      Nat Cell Biol. 6(10)

      Pages: 1003-1009

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591280
  • [Patent] 癌の抑制方法2007

    • Inventor(s)
      太田智彦
    • Industrial Property Rights Holder
      聖マリアンナ医科大学・太田智彦
    • Acquisition Date
      2007-06-21
    • Overseas
    • Data Source
      KAKENHI-PROJECT-19044042
  • [Patent] 癌の抑制方法2007

    • Inventor(s)
      太田智彦
    • Industrial Property Rights Holder
      聖マリアンナ医科大学・太田智彦
    • Acquisition Date
      2007-06-21
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Patent] 癌の抑制方法2007

    • Inventor(s)
      太田 智彦
    • Industrial Property Rights Holder
      聖マリアンナ医科大学・太田 智彦
    • Acquisition Date
      2007-06-21
    • Description
      「研究成果報告書概要(和文)」より
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Presentation] Does Trop-2 expression really not matter for the sensitivity to sacituzumab govitecan?2023

    • Author(s)
      Tomohiko Ohta
    • Organizer
      Best of San Antonio Breast Cancer Symposium (SABCS) 2022 in Kyoto
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03748
  • [Presentation] BRCA1とヒストン修飾を介したDNA相同組換え修復2023

    • Author(s)
      太田智彦
    • Organizer
      第3回JOHBOC学術総会
    • Data Source
      KAKENHI-PROJECT-23K27668
  • [Presentation] 乳がんの臨床を左右する新規エピジェネティックメカニズム2021

    • Author(s)
      太田智彦
    • Organizer
      第29回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H03748
  • [Presentation] BRCA1 N末端の変異とPARP阻害剤感受性: E3リガーゼ活性についての再考2021

    • Author(s)
      太田智彦
    • Organizer
      第18回日本臨床腫瘍学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03748
  • [Presentation] ER陽性乳癌細胞における、薬剤耐性獲得に伴うDNA修復機構異常とPARP阻害薬感受性2021

    • Author(s)
      鈴木友菜, 豊澤大地, 呉文文, 太田智彦, 林慎一
    • Organizer
      第29回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H03748
  • [Presentation] DNA修復脆弱性を標的としたがん治療2020

    • Author(s)
      太田智彦
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H03748
  • [Presentation] エストロゲン受容体の発現を制御するFbxo22は浸潤性小葉癌の予後因子となりうるか2020

    • Author(s)
      中川紗紀, 宮下穣, 江幡明子, 佐藤章子, 原田成美, 濱中洋平, 甘利正和, 平川久, 大井恭代, 太田智彦, 多田寛, 石田孝宣
    • Organizer
      第28回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H03748
  • [Presentation] CDK4/6阻害薬耐性細胞はDNA修復機構に異常をきたしPARP阻害薬に反応する2020

    • Author(s)
      鈴木友菜, 豊澤大地, 呉文文, 丹羽俊文, 太田智彦, 林慎一
    • Organizer
      第28回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H03748
  • [Presentation] PARP阻害剤耐性獲得に対する治療戦略2019

    • Author(s)
      太田智彦, 朱明章, 呉文文
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17H03585
  • [Presentation] HERC2 ubiquitinates RPA2 in ATR dependent manner and promotes RPA to suppress G-quadruplex DNA.2019

    • Author(s)
      Yongqiang Lai, Mingzhang Zhu, Wenwen Wu, Yukiko Togashi, Tomohiko Ohta.
    • Organizer
      11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03585
  • [Presentation] SERM感受性決定因子Fbxo22によるLuminal乳がん高リスク群の同定2019

    • Author(s)
      太田智彦
    • Organizer
      第27回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17H03585
  • [Presentation] PARP 阻害剤耐性とその克服戦略2019

    • Author(s)
      太田智彦
    • Organizer
      第17回日本臨床腫瘍学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H03585
  • [Presentation] HERC2はグアニン四重鎖(G4)の主要な制御因子としてG4安定化剤の感受性を左右する.2018

    • Author(s)
      呉文文, 竹内淳, 頼勇強, 三好康雄, 鈴木直, 佐伯泰, 田中啓二, 朱明章, 太田智彦.
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17H03585
  • [Presentation] HERC2 promotes BLM and WRN functions to suppress G-quadruplex DNA.2018

    • Author(s)
      Tomohiko Ohta.
    • Organizer
      EMBO Meeting Cellular signalling and cancer therapy 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03585
  • [Presentation] Resistance of Fbxo22 knockout cancer cells to poly(ADP-ribose)polymerase(PARP)inhibitor.2017

    • Author(s)
      頼勇強, 呉文文, 梁偉新, 太田智彦
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K15712
  • [Presentation] 乳癌におけるDNA損傷修復不全とPARP阻害剤感受性2017

    • Author(s)
      太田智彦
    • Organizer
      第25回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K15712
  • [Presentation] Resistance of Fbxo22 knockout cancer cells to poly(ADP-ribose)polymerase(PARP)inhibitor.2017

    • Author(s)
      頼勇強, 呉文文, 梁偉新, 太田智彦
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17H03585
  • [Presentation] Resistance of Fbxo22 knockout cancer cells to poly(ADP-ribose)polymerase(PARP)inhibitor.2017

    • Author(s)
      頼勇強, 呉文文, 梁偉新, 太田智彦
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-26290042
  • [Presentation] A novel role of HERC2 in maintaining chromosomal stability.2017

    • Author(s)
      Tomohiko Ohta
    • Organizer
      6th US-Japan DNA Repair Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15712
  • [Presentation] A novel role of HERC2 in maintaining chromosomal stability.2017

    • Author(s)
      Tomohiko Ohta
    • Organizer
      6th US-Japan DNA Repair Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03585
  • [Presentation] 乳癌におけるDNA損傷修復不全とPARP阻害剤感受性2017

    • Author(s)
      太田智彦
    • Organizer
      第25回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17H03585
  • [Presentation] 乳癌におけるDNA損傷修復不全とPARP阻害剤感受性2017

    • Author(s)
      太田智彦
    • Organizer
      第25回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-26290042
  • [Presentation] A novel role of HERC2 in maintaining chromosomal stability.2017

    • Author(s)
      Tomohiko Ohta
    • Organizer
      6th US-Japan DNA Repair Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26290042
  • [Presentation] DNA損傷修復機構に関与するユビキチンE3リガーセの検討2016

    • Author(s)
      敦賀智子, 岡田麻衣子, 黒田貴子, 宇井彩子, 太田智彦
    • Organizer
      第24回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-26290042
  • [Presentation] TripleNegative型乳癌(Basal型)においてLSD1蛋白の過剰発現は予後不良因子である2016

    • Author(s)
      永澤慧, 前田一郎, 太田智彦, 津川浩一郎
    • Organizer
      第24回日本乳癌学会学術総会
    • Place of Presentation
      東京ビックサイト(東京都江東区)
    • Year and Date
      2016-06-16
    • Data Source
      KAKENHI-PROJECT-16K15712
  • [Presentation] TripleNegative型乳癌(Basal型)においてLSD1蛋白の過剰発現は予後不良因子である2016

    • Author(s)
      永澤慧, 前田一郎, 太田智彦, 津川浩一郎
    • Organizer
      第24回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-26290042
  • [Presentation] ドキシサイクリン誘導性BRCA1欠損ERα陽性細胞を用いた染色体不安定化機構の解析2016

    • Author(s)
      黒田貴子, 岡田麻衣子, 敦賀智子, 太田智彦, 津川浩一郎
    • Organizer
      第24回日本乳癌学会学術総会
    • Place of Presentation
      東京ビックサイト(東京都江東区)
    • Year and Date
      2016-06-16
    • Data Source
      KAKENHI-PLANNED-24112005
  • [Presentation] BRCA変異陽性乳がんにおけるPrecision Medicine -基礎から臨床へ-2016

    • Author(s)
      太田智彦
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-07
    • Data Source
      KAKENHI-PLANNED-24112005
  • [Presentation] TripleNegative型乳癌(Basal型)においてLSD1蛋白の過剰発現は予後不良因子である2016

    • Author(s)
      永澤慧, 前田一郎, 太田智彦, 津川浩一郎
    • Organizer
      第24回日本乳癌学会学術総会
    • Place of Presentation
      東京ビックサイト(東京都江東区)
    • Year and Date
      2016-06-16
    • Data Source
      KAKENHI-PLANNED-24112005
  • [Presentation] DNA損傷修復機構に関与するユビキチンE3リガーセの検討2016

    • Author(s)
      敦賀智子, 岡田麻衣子, 黒田貴子, 宇井彩子, 太田智彦
    • Organizer
      第24回日本乳癌学会学術総会
    • Place of Presentation
      東京ビックサイト(東京都江東区)
    • Year and Date
      2016-06-16
    • Data Source
      KAKENHI-PLANNED-24112005
  • [Presentation] BRCA変異陽性乳がんにおけるPrecision Medicine -基礎から臨床へ-2016

    • Author(s)
      太田智彦
    • Organizer
      第75回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-26290042
  • [Presentation] BRCA変異陽性乳がんにおけるPrecision Medicine -基礎から臨床へ-2016

    • Author(s)
      太田智彦
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-07
    • Data Source
      KAKENHI-PROJECT-16K15712
  • [Presentation] ドキシサイクリン誘導性BRCA1欠損ERα陽性細胞を用いた染色体不安定化機構の解析2016

    • Author(s)
      黒田貴子, 岡田麻衣子, 敦賀智子, 太田智彦, 津川浩一郎
    • Organizer
      第24回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-26290042
  • [Presentation] ドキシサイクリン誘導性BRCA1欠損ERα陽性細胞を用いた染色体不安定化機構の解析2016

    • Author(s)
      黒田貴子, 岡田麻衣子, 敦賀智子, 太田智彦, 津川浩一郎
    • Organizer
      第24回日本乳癌学会学術総会
    • Place of Presentation
      東京ビックサイト(東京都江東区)
    • Year and Date
      2016-06-16
    • Data Source
      KAKENHI-PROJECT-16K15712
  • [Presentation] DNA損傷修復機構に関与するユビキチンE3リガーセの検討2016

    • Author(s)
      敦賀智子, 岡田麻衣子, 黒田貴子, 宇井彩子, 太田智彦
    • Organizer
      第24回日本乳癌学会学術総会
    • Place of Presentation
      東京ビックサイト(東京都江東区)
    • Year and Date
      2016-06-16
    • Data Source
      KAKENHI-PROJECT-16K15712
  • [Presentation] HERC2 and its interactors in regulation of DNA damage response and cell cycle.2015

    • Author(s)
      太田智彦
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-26290042
  • [Presentation] HERC2 and its interactors in regulation of DNA damage response and cell cycle.2015

    • Author(s)
      太田智彦
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県・名古屋市)
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PLANNED-24112005
  • [Presentation] トランスレーショナルリサーチを進める上での問題点2015

    • Author(s)
      太田智彦, 前田一郎, 津川浩一郎
    • Organizer
      第23回日本乳癌学会学術総会
    • Place of Presentation
      東京国際フォーラム(東京都千代田区)
    • Year and Date
      2015-07-03
    • Data Source
      KAKENHI-PROJECT-26290042
  • [Presentation] トランスレーショナルリサーチを進める上での問題点2015

    • Author(s)
      太田智彦, 前田一郎, 津川浩一郎
    • Organizer
      第23回日本乳癌学会学術総会
    • Place of Presentation
      東京国際フォーラム(東京都・千代田区)
    • Year and Date
      2015-07-03
    • Data Source
      KAKENHI-PLANNED-24112005
  • [Presentation] HERC2 and its interactors in regulation of DNA damage response and cell cycle.2015

    • Author(s)
      太田智彦
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県・名古屋市)
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-26670730
  • [Presentation] トランスレーショナルリサーチを進める上での問題点2015

    • Author(s)
      太田智彦, 前田一郎, 津川浩一郎
    • Organizer
      第23回日本乳癌学会学術総会
    • Place of Presentation
      東京国際フォーラム(東京都・千代田区)
    • Year and Date
      2015-07-03
    • Data Source
      KAKENHI-PROJECT-26670730
  • [Presentation] HP1 amma mediates BARD1 retention on Lys9-dimethylated histone H3 at sites of DNA damage2014

    • Author(s)
      Tomohiko Ohta, Hiroyuki Nishikawa, Anna S. Sedukhina, Takayo Fukuda, Wenwen Wu
    • Organizer
      Fusion Conference DNA Replication as a Source of DNA Damage
    • Place of Presentation
      カサブランカ(モロッコ)
    • Year and Date
      2014-10-02
    • Data Source
      KAKENHI-PROJECT-26290042
  • [Presentation] BRCA1 retention at DNA double-strand breaks in homology-directed repair pathways2014

    • Author(s)
      Tomohiko Ohta
    • Organizer
      International Symposium on Homeostasis through development, life, and diseases
    • Place of Presentation
      群馬大学(群馬県前橋市)
    • Year and Date
      2014-11-07
    • Data Source
      KAKENHI-PROJECT-26670730
  • [Presentation] BRCA1の新規クロマチン結合機構を標的としたがん治療戦略2014

    • Author(s)
      太田智彦
    • Organizer
      第15回ホルモンと癌研究会
    • Place of Presentation
      艮陵会館(宮城県仙台市)
    • Year and Date
      2014-07-04
    • Data Source
      KAKENHI-PLANNED-24112005
  • [Presentation] Therapeutic strategy targeting the mechanism of BRCA1 retention at DNA damage sites via a histone modification.2014

    • Author(s)
      太田智彦
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PROJECT-26290042
  • [Presentation] BRCA1 retention at DNA double-strand breaks in homology-directed repair pathways2014

    • Author(s)
      Tomohiko Ohta
    • Organizer
      International Symposium on Homeostasis through development, life, and diseases
    • Place of Presentation
      群馬大学(群馬県前橋市)
    • Year and Date
      2014-11-07
    • Data Source
      KAKENHI-PROJECT-26290042
  • [Presentation] BRCA1の新規DNA損傷応答メカニズムを標的とした治療戦略2014

    • Author(s)
      太田智彦
    • Organizer
      第22回日本乳癌学会学術総会
    • Place of Presentation
      大阪国際会議場(大阪府大阪市)
    • Year and Date
      2014-07-10
    • Data Source
      KAKENHI-PROJECT-26670730
  • [Presentation] BRCA1のDNA損傷応答とヒストン修飾2014

    • Author(s)
      太田智彦
    • Organizer
      第19回日本病態プロテアーゼ学会学術集会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府豊中市)
    • Year and Date
      2014-08-09
    • Data Source
      KAKENHI-PROJECT-26670730
  • [Presentation] Therapeutic strategy targeting the mechanism of BRCA1 retention at DNA damage sites via a histone modification.2014

    • Author(s)
      太田智彦
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PROJECT-26670730
  • [Presentation] BRCA1のDNA損傷応答とヒストン修飾2014

    • Author(s)
      太田智彦
    • Organizer
      第19回日本病態プロテアーゼ学会学術集会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府豊中市)
    • Year and Date
      2014-08-09
    • Data Source
      KAKENHI-PROJECT-26290042
  • [Presentation] HP1 amma mediates BARD1 retention on Lys9-dimethylated histone H3 at sites of DNA damage2014

    • Author(s)
      Tomohiko Ohta, Hiroyuki Nishikawa, Anna S. Sedukhina, Takayo Fukuda, Wenwen Wu
    • Organizer
      Fusion Conference DNA Replication as a Source of DNA Damage
    • Place of Presentation
      カサブランカ(モロッコ)
    • Year and Date
      2014-10-02
    • Data Source
      KAKENHI-PLANNED-24112005
  • [Presentation] BRCA1の新規クロマチン結合機構を標的としたがん治療戦略2014

    • Author(s)
      太田智彦
    • Organizer
      第15回ホルモンと癌研究会
    • Place of Presentation
      艮陵会館(宮城県仙台市)
    • Year and Date
      2014-07-04
    • Data Source
      KAKENHI-PROJECT-26290042
  • [Presentation] ATM-dependent but RNF168-independent BRCA1/BARD1 retention at sites of DNA damage2014

    • Author(s)
      Tomohiko Ohta, Hiroyuki Nishikawa, Anna S. Sedukhina, Takayo Fukuda, Wenwen Wu
    • Organizer
      Benzon Symposium No 60 - Nuclear Regulation by Ubiquitin
    • Place of Presentation
      コペンハーゲン(デンマーク)
    • Year and Date
      2014-08-18
    • Data Source
      KAKENHI-PROJECT-26290042
  • [Presentation] ATM-dependent but RNF168-independent BRCA1/BARD1 retention at sites of DNA damage2014

    • Author(s)
      Tomohiko Ohta, Hiroyuki Nishikawa, Anna S. Sedukhina, Takayo Fukuda, Wenwen Wu
    • Organizer
      Benzon Symposium No 60 - Nuclear Regulation by Ubiquitin
    • Place of Presentation
      コペンハーゲン(デンマーク)
    • Year and Date
      2014-08-18
    • Data Source
      KAKENHI-PROJECT-26670730
  • [Presentation] BRCA1のDNA損傷応答とヒストン修飾2014

    • Author(s)
      太田智彦
    • Organizer
      第19回日本病態プロテアーゼ学会学術集会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府豊中市)
    • Year and Date
      2014-08-09
    • Data Source
      KAKENHI-PLANNED-24112005
  • [Presentation] HP1 amma mediates BARD1 retention on Lys9-dimethylated histone H3 at sites of DNA damage2014

    • Author(s)
      Tomohiko Ohta, Hiroyuki Nishikawa, Anna S. Sedukhina, Takayo Fukuda, Wenwen Wu
    • Organizer
      Fusion Conference DNA Replication as a Source of DNA Damage
    • Place of Presentation
      カサブランカ(モロッコ)
    • Year and Date
      2014-10-02
    • Data Source
      KAKENHI-PROJECT-26670730
  • [Presentation] BRCA1の新規DNA損傷応答メカニズムを標的とした治療戦略2014

    • Author(s)
      太田智彦
    • Organizer
      第22回日本乳癌学会学術総会
    • Place of Presentation
      大阪国際会議場(大阪府大阪市)
    • Year and Date
      2014-07-10
    • Data Source
      KAKENHI-PLANNED-24112005
  • [Presentation] ATM-dependent but RNF168-independent BRCA1/BARD1 retention at sites of DNA damage2014

    • Author(s)
      Tomohiko Ohta, Hiroyuki Nishikawa, Anna S. Sedukhina, Takayo Fukuda, Wenwen Wu
    • Organizer
      Benzon Symposium No 60 - Nuclear Regulation by Ubiquitin
    • Place of Presentation
      コペンハーゲン(デンマーク)
    • Year and Date
      2014-08-18
    • Data Source
      KAKENHI-PLANNED-24112005
  • [Presentation] Therapeutic strategy targeting the mechanism of BRCA1 retention at DNA damage sites via a histone modification.2014

    • Author(s)
      太田智彦
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PLANNED-24112005
  • [Presentation] BRCA1の新規DNA損傷応答メカニズムを標的とした治療戦略2014

    • Author(s)
      太田智彦
    • Organizer
      第22回日本乳癌学会学術総会
    • Place of Presentation
      大阪国際会議場(大阪府大阪市)
    • Year and Date
      2014-07-10
    • Data Source
      KAKENHI-PROJECT-26290042
  • [Presentation] BRCA1の新規クロマチン結合機構を標的としたがん治療戦略2014

    • Author(s)
      太田智彦
    • Organizer
      第15回ホルモンと癌研究会
    • Place of Presentation
      艮陵会館(宮城県仙台市)
    • Year and Date
      2014-07-04
    • Data Source
      KAKENHI-PROJECT-26670730
  • [Presentation] BRCA1 retention at DNA double-strand breaks in homology-directed repair pathways2014

    • Author(s)
      Tomohiko Ohta
    • Organizer
      International Symposium on Homeostasis through development, life, and diseases
    • Place of Presentation
      群馬大学(群馬県前橋市)
    • Year and Date
      2014-11-07
    • Data Source
      KAKENHI-PLANNED-24112005
  • [Presentation] DNA損傷応答におけるBRCA1,Claspinおよび HERC2の相互作用2013

    • Author(s)
      太田 智彦
    • Organizer
      第65回日本細胞生物学会大会
    • Place of Presentation
      ウインクあいち(愛知県産業労働センター)
    • Year and Date
      2013-06-21
    • Data Source
      KAKENHI-PROJECT-23300358
  • [Presentation] DNA損傷応答とBRCA1ユビキチンリガーゼ2013

    • Author(s)
      太田 智彦
    • Organizer
      第86回日本生化学学会大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2013-09-12
    • Data Source
      KAKENHI-PROJECT-23300358
  • [Presentation] BRCA1-E3 inactivation leads to a failure of homologous recombination DNA repair in response to CPT-11 and PARPi2013

    • Author(s)
      太田 智彦
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2013-10-03
    • Data Source
      KAKENHI-PROJECT-23300358
  • [Presentation] Homology-directed DNA repair competence as a possible biomarker for breast cancer chemosensitivity2013

    • Author(s)
      太田 智彦
    • Organizer
      第11回日本臨床腫瘍学学会集会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2013-08-29
    • Data Source
      KAKENHI-PROJECT-23300358
  • [Presentation] Agent-specific cellular chemosensitivity attributed to loss of BRCA1 E3 ligase activity2012

    • Author(s)
      太田 智彦
    • Organizer
      15th International Congress on Hormonal Steroids and Hormones & Cancer
    • Place of Presentation
      石川県立音楽堂
    • Year and Date
      2012-11-15
    • Data Source
      KAKENHI-PROJECT-23300358
  • [Presentation] DNA replication and checkpoint regulated by HERC2 and BRCA1 E3 ubiquitin ligases2012

    • Author(s)
      太田 智彦
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      さっぽろ芸文館
    • Year and Date
      2012-09-19
    • Data Source
      KAKENHI-PROJECT-23300358
  • [Presentation] DNA replication and checkpoint regulated by HERC2 and BRCA1 E3 ubiquitin ligases2012

    • Author(s)
      太田 智彦
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      さっぽろ芸文館(北海道)
    • Year and Date
      2012-09-19
    • Data Source
      KAKENHI-PLANNED-24112005
  • [Presentation] Agent-specific cellular chemosensitivity attributed to loss of BRCA1 E3 ligase activity2012

    • Author(s)
      太田 智彦
    • Organizer
      15th International Congress on Hormonal Steroids and Hormones Cancer
    • Place of Presentation
      石川県立音楽堂(石川県)
    • Year and Date
      2012-11-15
    • Data Source
      KAKENHI-PLANNED-24112005
  • [Presentation] トリプルネガティブ乳癌に対する治療戦略2011

    • Author(s)
      太田智彦
    • Organizer
      第19回日本乳癌学会学術集会プレジデンシャルシンポジウム
    • Place of Presentation
      仙台国際センター東北大学百周年記念会館(宮城県)
    • Year and Date
      2011-09-04
    • Data Source
      KAKENHI-PROJECT-23300358
  • [Presentation] トリプルネガティブ乳癌に対する治療戦略2011

    • Author(s)
      太田智彦
    • Organizer
      第19回日本乳癌学会学術集会ブレジデンシャルシンポジウム
    • Place of Presentation
      仙台国際センター東北大学百周年記念会館(宮城県)
    • Year and Date
      2011-09-04
    • Data Source
      KAKENHI-PUBLICLY-23131514
  • [Presentation] トリプルネガティブ乳癌に対する治療戦略2011

    • Author(s)
      太田 智彦
    • Organizer
      第19回日本乳癌学会学術集会
    • Place of Presentation
      仙台国際センター東北大学百周年記念会館
    • Year and Date
      2011-09-04
    • Data Source
      KAKENHI-PROJECT-23300358
  • [Presentation] 乳がんのDNA相同組換え修復異常とユビキチン2010

    • Author(s)
      太田智彦
    • Organizer
      第69回日本癌学会学術総会、シンポジウム
    • Place of Presentation
      大阪(大阪国際会議場)
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Presentation] The DNA damage repair pathway in breast cancer chemotherapy2010

    • Author(s)
      Tomohiko Ohta
    • Organizer
      The 23rd International Symposium of the Foundation for Promotion of Cancer Research "Recent Progress on Breast
    • Place of Presentation
      東京(国立がんセンター)
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Presentation] 乳がんのDNA相同組換え修復異常とユビキチン2010

    • Author(s)
      太田智彦
    • Organizer
      第69回日本癌学会学術総会・シンポジウム
    • Place of Presentation
      大阪国際会議場(大阪)
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Presentation] DNA損傷応答と乳癌の薬剤感受性2010

    • Author(s)
      太田智彦
    • Organizer
      第18回日本乳癌学会学術総会・シンポジウム
    • Place of Presentation
      ロイトン札幌(北海道)
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Presentation] Recruitment of phosphorylated NPM1 to sites of DNA damage through RNF8-dependent ubiquitin conjugates.2010

    • Author(s)
      太田智彦
    • Organizer
      EMBO Workshop-The interface between the ubiquitin family and the DNA damage response.
    • Place of Presentation
      Hotel Istra (Croatia)
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Presentation] DNA損傷応答と乳癌の薬剤感受性2010

    • Author(s)
      太田智彦
    • Organizer
      第18回日本乳癌学会学術総会、シンポジウム
    • Place of Presentation
      北海道(ロイトン札幌)
    • Data Source
      KAKENHI-PUBLICLY-21025032
  • [Presentation] The DNA damage repair pathway in breast cancer chemotherapy2010

    • Author(s)
      Tomohiko Ohta
    • Organizer
      The 23rd International Symposium of the Foundation for Promotion of Cancer Research "Recent Progress on Breast
    • Place of Presentation
      東京(国立がんセンター)
    • Data Source
      KAKENHI-PUBLICLY-21025032
  • [Presentation] Recruitment of phosphorylated NPM1 to sites of DNA damage through RNF8-dependent ubiquitin conjugates.2010

    • Author(s)
      Tomohiko Ohta
    • Organizer
      EMBO Workshop-The interface between the ubiquitin family and the DNA damage response.-
    • Place of Presentation
      Croatia (Hotel Istra)
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Presentation] DNA損傷応答と乳癌の薬剤感受性2010

    • Author(s)
      太田智彦
    • Organizer
      第18回日本乳癌学会学術総会、シンポジウム
    • Place of Presentation
      北海道(ロイトン札幌)
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Presentation] The DNA damage repair pathway in breast cancer chemotherapy.2010

    • Author(s)
      太田智彦
    • Organizer
      The 23rd International Symposium of the Foundation for Promotion of Cancer Research
    • Place of Presentation
      国立がんセンター Recent Progress on Breast Cancer(東京都)
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Presentation] 乳がんのDNA相同組換え修復異常とユビキチン2010

    • Author(s)
      太田智彦
    • Organizer
      第69回日本癌学会学術総会、シンポジウム
    • Place of Presentation
      大阪(大阪国際会議場)
    • Data Source
      KAKENHI-PUBLICLY-21025032
  • [Presentation] Recruitment of phosphorylated NPM1 to sites of DNA damage through RNF8-dependent ubiquitin conjugates.2010

    • Author(s)
      Tomohiko Ohta
    • Organizer
      EMBO Workshop-The interface between the ubiquitin family and the DNA damage response.-
    • Place of Presentation
      Croatia (Hotel Istra)
    • Data Source
      KAKENHI-PUBLICLY-21025032
  • [Presentation] BRCA1機能不全をtargetにした乳癌の化学療法2009

    • Author(s)
      太田智彦
    • Organizer
      第109回日本外科学会定期学術集会
    • Place of Presentation
      福岡国際会議場(福岡県)
    • Year and Date
      2009-04-02
    • Data Source
      KAKENHI-PUBLICLY-21025032
  • [Presentation] BRCA1機能不全をtargetにした乳癌の化学療法2009

    • Author(s)
      太田智彦
    • Organizer
      第109回日本外科学会定期学術集会
    • Place of Presentation
      福岡国際会議場(福岡県)
    • Year and Date
      2009-04-02
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Presentation] 乳癌の化学療法感受性とBRCA12009

    • Author(s)
      太田智彦
    • Organizer
      第19回乳癌基礎研究会
    • Place of Presentation
      伊香保温泉(群馬県)
    • Year and Date
      2009-07-25
    • Data Source
      KAKENHI-PROJECT-20058036
  • [Presentation] 乳癌の化学療法感受性とBRCA12009

    • Author(s)
      太田智彦
    • Organizer
      第19回乳癌基礎研究会
    • Place of Presentation
      伊香保温泉(群馬県)
    • Year and Date
      2009-07-25
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Presentation] BRCA1機能不全をtargetにした乳癌の化学療法2009

    • Author(s)
      太田智彦
    • Organizer
      第109回日本外科学会定期学術集会
    • Place of Presentation
      福岡国際会議場(福岡県)
    • Year and Date
      2009-04-02
    • Data Source
      KAKENHI-PROJECT-20058036
  • [Presentation] 乳癌の化学療法感受性とBRCA12009

    • Author(s)
      太田智彦
    • Organizer
      第19回乳癌基礎研究会
    • Place of Presentation
      伊香保温泉(群馬県)
    • Year and Date
      2009-07-25
    • Data Source
      KAKENHI-PUBLICLY-21025032
  • [Presentation] DNA double-strand break repair mediated by BRCA1.2008

    • Author(s)
      太田智彦
    • Organizer
      26th Congress of the International Association for Breast Cancer Research.
    • Place of Presentation
      岡山県
    • Year and Date
      2008-09-23
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Presentation] BRCA1カスケードによる遺伝子恒常性維持と家族性腫瘍2008

    • Author(s)
      太田智彦
    • Organizer
      第1 4回日本家族性腫瘍学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-21
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Presentation] Candidate substrates of BRCAl in its multiple cellular functions2008

    • Author(s)
      Tomohiko Ohta
    • Organizer
      2^<nd> JCA-AACR special Joint Conference : The latest Advance in Breast Cancer Research From Basic Science to Therapeutics
    • Place of Presentation
      兵庫
    • Year and Date
      2008-07-14
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Presentation] BRCA1の機能から考えたBasal-like乳癌の薬剤感受性2008

    • Author(s)
      太田智彦
    • Organizer
      第16回日本乳癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2008-09-27
    • Data Source
      KAKENHI-PROJECT-20058036
  • [Presentation] BRCA1を標的とするユビキチンリガーゼの同定2008

    • Author(s)
      太田智彦
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-20058036
  • [Presentation] BRCA1を標的とするユビキチンリガーゼの同定2008

    • Author(s)
      太田智彦
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Presentation] Cooperation of BRCA1 and ubiquitin in the DNA damage response2008

    • Author(s)
      Ohta T.
    • Organizer
      The 23rd Nagoya international cancer treatment symposium
    • Place of Presentation
      Nagoya
    • Year and Date
      2008-01-27
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Presentation] DNA double-strand break repair mediated by BRCA12008

    • Author(s)
      Tomohiko Ohta
    • Organizer
      26^<th> Congress of the International Association fix Breast Cancer Research
    • Place of Presentation
      岡山
    • Year and Date
      2008-09-23
    • Data Source
      KAKENHI-PROJECT-19044042
  • [Presentation] Cooperation of BRCA1 and ubiquitin in the DNA damage response2008

    • Author(s)
      太田 智彦
    • Organizer
      第23回名古屋癌治療国際シンポジウム
    • Place of Presentation
      名古屋
    • Year and Date
      2008-01-27
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Presentation] Cooperation of BRCA1 and ubiquitin in the DNA damage response.2008

    • Author(s)
      Tomohiko Ohta
    • Organizer
      第23回名古屋癌治療国際シンポジウム
    • Place of Presentation
      名古屋
    • Year and Date
      2008-01-26
    • Data Source
      KAKENHI-PROJECT-19044042
  • [Presentation] BRCA1の機能から考えたBasal-like乳癌の薬剤感受性2008

    • Author(s)
      太田智彦
    • Organizer
      第16回日本乳癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2008-09-27
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Presentation] Cooperation of BRCA1 and ubiquitin in the DNA damage response2008

    • Author(s)
      Ohta T.
    • Organizer
      The 23rd Nagoya international cancer treatment symposium
    • Place of Presentation
      Nagoya
    • Year and Date
      2008-01-27
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591486
  • [Presentation] Cooperation of BRCAl and ubiquitin in the DNA damage response.2008

    • Author(s)
      Tomohiko Ohta
    • Organizer
      第23回名古屋癌治療国際シンポジウム
    • Place of Presentation
      名古屋
    • Year and Date
      2008-01-26
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Presentation] BRCA1の機能から考えたBasal-like乳癌の薬剤感受性2008

    • Author(s)
      太田智彦
    • Organizer
      第16回日本乳癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2008-09-27
    • Data Source
      KAKENHI-PROJECT-19044042
  • [Presentation] DNA double-strand break repair mediated by BRCA12008

    • Author(s)
      Tomohiko Ohta
    • Organizer
      26^<th> Congress of the International Association for Breast Cancer Research
    • Place of Presentation
      岡山
    • Year and Date
      2008-09-23
    • Data Source
      KAKENHI-PROJECT-20058036
  • [Presentation] Candidate substrates of BRCA1 in its multiple cellular functions.2008

    • Author(s)
      太田智彦
    • Organizer
      2nd JCA-AACR special Joint Conference : The latest Advance in Breast Cancer Research From Basic Science to Therapeutics.
    • Place of Presentation
      兵庫県
    • Year and Date
      2008-07-14
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Presentation] DNA double-strand break repair mediated by BRCAl2008

    • Author(s)
      Tomohiko Ohta
    • Organizer
      26^<th> Congress of the International Association for Breast Cancer Research
    • Place of Presentation
      岡山
    • Year and Date
      2008-09-23
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Presentation] Candidate substrates of BRCA1 in its multiple cellular functions2008

    • Author(s)
      Tomohiko Ohta
    • Organizer
      2^<nd> JCA-AACR special Joint Conference : The latest Advance in Braast Cancer Research From Basic Science to Therapeutics
    • Place of Presentation
      兵庫
    • Year and Date
      2008-07-14
    • Data Source
      KAKENHI-PROJECT-20058036
  • [Presentation] BRCA1カスケードによる遺伝子恒常性維持と家族性腫瘍2008

    • Author(s)
      太田智彦
    • Organizer
      第14回日本家族性腫瘍学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-21
    • Data Source
      KAKENHI-PROJECT-20058036
  • [Presentation] BRCA1カスケードによる遺伝子恒常性維持と家族性腫瘍2008

    • Author(s)
      太田智彦
    • Organizer
      第14回日本家族性腫瘍学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-21
    • Data Source
      KAKENHI-PROJECT-19044042
  • [Presentation] Candidate substrates of BRCA1 in its multiple cellular functions2008

    • Author(s)
      Tomohiko Ohta
    • Organizer
      2^<nd> JCA-AACR special Joint Conference : The latest Advance in Breast Cancer Research From Basic Science to Therapeutics
    • Place of Presentation
      兵庫
    • Year and Date
      2008-07-14
    • Data Source
      KAKENHI-PROJECT-19044042
  • [Presentation] BRCAlを標的とするュビキチンリガーゼの同定2008

    • Author(s)
      太田智彦
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Presentation] BRCA1の機能から考えたBasal-like乳癌の薬剤感受性2008

    • Author(s)
      太田智彦
    • Organizer
      第16回日本乳癌学会学術総会
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Year and Date
      2008-09-27
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Presentation] BRCA1カスケードによる遺伝子恒常性維持と家族性腫瘍2008

    • Author(s)
      太田智彦
    • Organizer
      第14回日本家族性腫瘍学会学術総会
    • Place of Presentation
      東京都
    • Year and Date
      2008-06-21
    • Data Source
      KAKENHI-PROJECT-20591557
  • [Presentation] BRCA1を標的とするユビキチンリガーゼの同定2008

    • Author(s)
      太田智彦
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-19044042
  • [Presentation] 細胞周期およびDNA損傷におけるBRCA1ユビキチンリガーゼの分子機能2007

    • Author(s)
      太田 智彦, et. al.
    • Organizer
      第66回日本癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-03
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Presentation] 細胞周期およびDNA損傷反応におけるBRCA1ユビキチンリガーゼの分子機能2007

    • Author(s)
      太田 智彦, 他
    • Organizer
      第66回日本癌学会総会・シンポジウム
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-03
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Presentation] Molecular functions of BRCA1E3 ubiquitin ligase in cell cycle and DNA damage response2007

    • Author(s)
      Ohta T., Wu W, Fukuda M.
    • Organizer
      The 66th annual meeting of the Japanese cancer association
    • Place of Presentation
      Yokohama
    • Year and Date
      2007-10-03
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591486
  • [Presentation] Molecular functions of BRCA1E3 ubiquitin ligase in cell cycle and DNA damage response2007

    • Author(s)
      Ohta T., Wu W., Fukuda M.
    • Organizer
      The 66th annual meeting of the Japanese cancer association
    • Place of Presentation
      Yokohama
    • Year and Date
      2007-10-03
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Presentation] Molecular functions of BRCA1 E3 ubiquitin ligase in cell cycle and DNA damage response2007

    • Author(s)
      Ohta T.
    • Organizer
      The 66th annual meeting of the Japanese cancer association
    • Place of Presentation
      Yokohama
    • Year and Date
      2007-10-03
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591486
  • [Presentation] 細胞周期およびDNA損傷におけるBRCA1ユビキチンリガーゼの分子機能2007

    • Author(s)
      太田 智彦, et. al.
    • Organizer
      第66回日本癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-03
    • Data Source
      KAKENHI-PROJECT-19044042
  • [Presentation] Roles of BRCA1's enzyme activity in breast and ovarian tumor Suppression2006

    • Author(s)
      Ohta T.
    • Organizer
      The 95th annual congress of the Japanese society of pathology
    • Place of Presentation
      Siniuku
    • Year and Date
      2006-04-30
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591486
  • [Presentation] The enzyme activity of breast and ovarian tumor suppresser BRCA12006

    • Author(s)
      Ohta T.
    • Organizer
      The 12th annual congress of the Japanese society for familial tumors
    • Place of Presentation
      Suita
    • Year and Date
      2006-06-16
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591486
  • [Presentation] 乳癌および卵巣癌抑制におけるBRCA1酵素活性の役割2006

    • Author(s)
      太田 智彦
    • Organizer
      第95回日本病理学会総会・シンポジウム
    • Place of Presentation
      新宿
    • Year and Date
      2006-04-30
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Presentation] Breast and ovarian tumor suppression by BRCA1's enzyme activity2006

    • Author(s)
      Ohta T.
    • Organizer
      The 43th congress of the Japanese society of molecular medicine
    • Place of Presentation
      Sapporo
    • Year and Date
      2006-07-20
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Presentation] The enzyme activity of breast and ovarian tumor suppresser BRCA12006

    • Author(s)
      Ohta T.
    • Organizer
      The 95th annual congress of the Japanese society of pathology
    • Place of Presentation
      Sinjuku
    • Year and Date
      2006-04-30
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591486
  • [Presentation] Ubiquitin ligase activity of BRCA1,a hub protein that regulates multiple cellular pathways2006

    • Author(s)
      Ohta T.
    • Organizer
      MBSJ forum 2006 of the molecular biology society of Japan
    • Place of Presentation
      Nagoya
    • Year and Date
      2006-12-07
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591486
  • [Presentation] BRCA1の酵素活性による乳癌および卵巣癌抑制2006

    • Author(s)
      太田 智彦
    • Organizer
      第43回日本臨床分子医学会学術集会・シンポジウム
    • Place of Presentation
      札幌
    • Year and Date
      2006-07-20
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Presentation] Roles of BRCA1's Enzyme Activity in the Maintenance of Genomic Stability2006

    • Author(s)
      Ohta T.
    • Organizer
      The 49th annual meeting of the Japan radiation research society
    • Place of Presentation
      Sapporo
    • Year and Date
      2006-09-08
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591486
  • [Presentation] Ubiquitin ligase activity of BRCA1, a hub protein that regulates multiple cellular pathways2006

    • Author(s)
      Ohta T., Wu W, Fukuda M.
    • Organizer
      MBSJ forum 2006 of the molecular biology society of Japan
    • Place of Presentation
      Nagoya
    • Year and Date
      2006-12-07
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591486
  • [Presentation] ゲノム安定性維持におけるBRCA1酵素活性の役割2006

    • Author(s)
      太田 智彦
    • Organizer
      第49回日本放射線影響学会・シンポジウム
    • Place of Presentation
      札幌
    • Year and Date
      2006-09-08
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Presentation] 多様な細胞内径路を制御するBRCA1のユビキチンリガーゼ活性2006

    • Author(s)
      太田 智彦, 他
    • Organizer
      日本分子生物学会2006フォーラム・シンポジウム
    • Place of Presentation
      名古屋
    • Year and Date
      2006-12-07
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Presentation] Ubiquitin ligase activity of BRCA1, a hub protein that regulates multiple cellular pathways2006

    • Author(s)
      Ohta T., Wu W., Fukuda M.
    • Organizer
      MBSJ forum 2006 of the molecular biology society of Japan
    • Place of Presentation
      Nagoya
    • Year and Date
      2006-12-07
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Presentation] 乳癌および卵巣癌抑制遺伝子産物BRCA1の酵素活性2006

    • Author(s)
      太田 智彦
    • Organizer
      第12回日本家族性腫瘍学会学術総会・シンポジウム
    • Place of Presentation
      吹田
    • Year and Date
      2006-06-16
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Presentation] The enzyme activity of breast and ovarian tumor suppresser BRCA12006

    • Author(s)
      Ohta T.
    • Organizer
      The 12th annual congress of the Japanese society for familial tumors
    • Place of Presentation
      Suita
    • Year and Date
      2006-06-16
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Presentation] Breast and ovarian tumor suppression by BRCA1's enzyme activity2006

    • Author(s)
      Ohta T.
    • Organizer
      The 43th congress of the Japanese society of molecular medicine
    • Place of Presentation
      Sapporo
    • Year and Date
      2006-07-20
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591486
  • [Presentation] Roles of BRCA1's Enzyme Activity in the Maintenance of Genomic Stability2006

    • Author(s)
      Ohta T.
    • Organizer
      The 49th annual meeting of the Japan radiation research society
    • Place of Presentation
      Sapporo
    • Year and Date
      2006-09-08
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Presentation] Roles of BRCA1's enzyme activity in breast and ovarian tumor Suppression2006

    • Author(s)
      Ohta T.
    • Organizer
      The 95th annual congress of the Japanese society of pathology
    • Place of Presentation
      Sinjuku
    • Year and Date
      2006-04-30
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591446
  • [Presentation] DNA損傷応答とBRCA1ユビキチンリガーゼ

    • Author(s)
      太田 智彦
    • Organizer
      第86回日本生化学学会大会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23300358
  • [Presentation] Agent-specific cellular chemosensitivity attributed to loss of BRCA1 E3 ligase activity

    • Author(s)
      太田 智彦
    • Organizer
      15th International Congress on Hormonal Steroids and Hormones & Cancer
    • Place of Presentation
      石川県立音楽堂(石川県)
    • Data Source
      KAKENHI-PROJECT-23300358
  • [Presentation] BRCA1-E3 inactivation leads to a failure of homologous recombination DNA repair in response to CPT-11 and PARPi

    • Author(s)
      太田 智彦
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PLANNED-24112005
  • [Presentation] DNA損傷応答とBRCA1ユビキチンリガーゼ

    • Author(s)
      太田 智彦
    • Organizer
      第86回日本生化学学会大会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PLANNED-24112005
  • [Presentation] BRCA1-E3 inactivation leads to a failure of homologous recombination DNA repair in response to CPT-11 and PARPi

    • Author(s)
      太田 智彦
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23300358
  • [Presentation] DNA損傷応答におけるBRCA1, ClaspinおよびHERC2の相互作用

    • Author(s)
      太田 智彦
    • Organizer
      第65回日本細胞生物学会大会
    • Place of Presentation
      ウインクあいち(愛知県産業労働センター)
    • Data Source
      KAKENHI-PROJECT-23300358
  • [Presentation] DNA損傷応答におけるBRCA1, ClaspinおよびHERC2の相互作用

    • Author(s)
      太田 智彦
    • Organizer
      第65回日本細胞生物学会大会
    • Place of Presentation
      ウインクあいち(愛知県産業労働センター)
    • Data Source
      KAKENHI-PLANNED-24112005
  • [Presentation] Homology-directed DNA repair competence as a possible biomarker for breast cancer chemosensitivity

    • Author(s)
      太田 智彦
    • Organizer
      第11回日本臨床腫瘍学会集会
    • Place of Presentation
      仙台国際センター
    • Data Source
      KAKENHI-PROJECT-23300358
  • [Presentation] DNA replication and checkpoint regulated by HERC2 and BRCA1 E3 ubiquitin ligases

    • Author(s)
      太田 智彦
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      さっぽろ芸文館(北海道)
    • Data Source
      KAKENHI-PROJECT-23300358
  • [Presentation] Homology-directed DNA repair competence as a possible biomarker for breast cancer chemosensitivity

    • Author(s)
      太田 智彦
    • Organizer
      第11回日本臨床腫瘍学会集会
    • Place of Presentation
      仙台国際センター
    • Data Source
      KAKENHI-PLANNED-24112005
  • 1.  FUKUDA Mamoru (50081724)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  OGATA Haruki (60267581)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  BOKU Narikazu (50505948)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  TSUGAWA Koichiro (60313657)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  NAKADA Shinichiro (70548528)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  TADOKORO Mamoru (80081644)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  TAKAKUWA Toshifumi (90121201)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  ARIMURA Toshihiro (70232072)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  OTSUBO Takehito (50398971)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 10.  中島 利博 (90260752)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  福田 護 (70059442)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  渡部 省二 (30113020)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  WU Wenwen
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 8 results
  • 14.  KATO Akihiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  UMEZU Tomohiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  SUZUKI Hiromu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  城村 由和
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  高田 穣
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 19.  平 直江
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  西川 裕之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  中村 修平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  勝木 陽子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  井ノ上 逸朗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  鈴木 穣
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  中西 真
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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