Takumi Akashi 明石巧

… Alternative Names

明石巧アカシタクミ

AKASHI Takumi 明石巧

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Researcher Number	60242202
Affiliation (Current)	2025: 東京科学大学, その他の部局等, 非常勤講師
Affiliation (based on the past Project Information) *help	2021: 東京医科歯科大学, 東京医科歯科大学病院, 准教授 2018 – 2020: 東京医科歯科大学, 医学部附属病院, 准教授 2010 – 2015: 東京医科歯科大学, 医学部附属病院, 准教授 2011: 東京医科歯科大学, 医学部附属病院, 医系・准教授 2002 – 2003: 東京医科歯科大学, 医学部附属病院, 講師 … More 2001: 東京医科歯科大学, 医学部・附属病院, 講師 1999: 東京医科歯科大学, 医学部・付属病院, 助手 1998: 東京医科歯科大学, 医学部・附属病院, 助手 1996: 東京医科歯科大学, 医学部, 助手 1994: 東京医科歯科大学, 医学部・付属病院・病理部, 助手 1994: 東京医科歯科大学, 医学部付属病院病理部, 助手 Less
Review Section/Research Field	Principal Investigator Experimental pathology / Human pathology / Human pathology / Basic Section 49020:Human pathology-related Except Principal Investigator Thoracic surgery
Keywords	Principal Investigator 肺癌 / 浸潤 / 基底膜 / 大腸癌 / アクチン / cortactin / 浸潤突起 / ラミニン / 形態形成 / Gタンパク質 … More / Rap / 癌浸潤 / RapG蛋白 / LC/MS/MS質量分析 / 癌 / Src-superbinder / リン酸化チロシン / 質量分析 / Rap1 / proximity labeling / プロテオーム / 癌細胞 / cancer stromal interactin / cytokine / basement membrane / invasion / adnocarcinoma / lung cancer / cDNAアレイ / マトリゲル / 癌間質相互作用 / サイトカイン / 腺癌 / フォスファチジルイノシトール / phosphatidylinositol4,5P / 皮質アクチン線維 / phosphatidylinositol / ミオシン / ホスファチジルイノシトール / actinin1 / ect2 / 細胞極性 / 極性異常 / 極性 / RhoA・p21 / 間質浸潤 / メタロプロテアーゼ / プロテアーゼ … More Except Principal Investigator 病理学 / 蛋白質 / 肺癌 / EGFR / カルボキシペプチターゼM / 発がん動物モデル / 肺胞上皮細胞 / Lung Cancer / 肺がん / CPM / Carboxypeptidase M / カルボキシペプチダーゼM Less

Study of invasion mechanism of cancer cells by proteomic analysis of Rap pathwayPrincipal Investigator
- Principal Investigator
  
  Takumi Akashi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Tokyo Medical and Dental University
Study of lung cancer cell invasion mechanism through PtdIns imagingPrincipal Investigator
- Principal Investigator
  
  Akashi Takumi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tokyo Medical and Dental University
Alteration of apical-basal polarity regulating proteins Par/Lgl/Scrib in lung adenocarcinomas and its relationship with invasion and metastasisPrincipal Investigator
- Principal Investigator
  
  AKASHI Takumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tokyo Medical and Dental University
Study of Carboxypeptidase M expression profiles in patients with lung cancer
- Principal Investigator
  
  FUJIWARA Naoyuki
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Tokyo Medical and Dental University
Analysis of molecular mechanisms of basement membrane destruction in the process of lung cancer cell invasionPrincipal Investigator
- Principal Investigator
  
  AKASHI Takumi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tokyo Medical and Dental University
ヒト・ラミニンA5鎖遺伝子の新規クローニングと消化器癌における発現異常の解析Principal Investigator
- Principal Investigator
  
  明石巧
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Human pathology
- Research Institution
  Tokyo Medical and Dental University
大腸線癌細胞の転移浸潤に及ぼす低分子量GTP結合蛋白RhOA・p21の影響Principal Investigator
- Principal Investigator
  
  明石巧
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Medical and Dental University
大腸癌培養細胞の腺管構造形成過程におけるメタロプロテアーゼの役割Principal Investigator
- Principal Investigator
  
  明石巧
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Medical and Dental University
大腸癌培養細胞の腺管構造形成過程におけるメタロプロテアーゼの役割Principal Investigator
- Principal Investigator
  
  明石巧
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Medical and Dental University

All 2015 2014 2013 2011 2010

All Journal Article Presentation

[Journal Article] Localization of cortical actin filaments and its correlation with invasion and metastasis in lung adenocarcinomas2015
- Author(s)
  Shohei Tomii、Takumi Akashi, Noboru Ando, Sekine Masaki, Yoshimi Suzuki, Asuka Furukawa, Yoshinobu Eishi
- Journal Title
  
  Proceedings of The L.Japanese Society of Pathology
  
  Volume: 104 Pages: 453-453
- Data Source
  KAKENHI-PROJECT-25460433
[Journal Article] 肺腺癌における皮質アクチン線維の細胞内局在と浸潤との相関2015
- Author(s)
  冨井翔平, 明石巧, 安藤登, 鈴木好美, 古川明日香, 江石義信
- Journal Title
  
  日本病理学会会誌
  
  Volume: 104 Pages: 453-453
- Data Source
  KAKENHI-PROJECT-25460433
[Journal Article] Propionibacterium acnes infection in glandular epithelium and stromal macrophages of the prostate with or without cancer2014
- Author(s)
  Bae Y, Ito T, Iida T, Uchida K, Sekine M, Nakajima Y, Kumagai J, Yokoyama T, Kawachi H, Akashi T, Eishi Y
- Journal Title
  
  PloS one
  
  Volume: 9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460433
[Journal Article] Higher serum CCL17 may be a promising predictor of acute exacerbations in chronic hypersensitivity pneumonitis2013
- Author(s)
  Miyazaki Y, Unoura K, Tateishi T, Akashi T, Takemura T, Tomita M, Inase N, Yoshizawa Y:
- Journal Title
  
  Respiratory Res
  
  Volume: 14 Pages: 57-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460433
[Journal Article] The expression profiles of acidic epithelial keratins in Ameloblastoma.2013
- Author(s)
  Pal KS, Sakamoto K, Aragaki T, Akashi T, Yamaguchi A
- Journal Title
  
  Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology
  
  Volume: 115 Issue: 4 Pages: 523-531
- DOI
  10.1016/j.oooo.2013.01.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249061, KAKENHI-PROJECT-25253098, KAKENHI-PROJECT-25460433
[Journal Article] Localization of the Invadopodia- Related Proteins Actinin-1 and Cortactin to Matrix-Contact-Side Cytoplasm of Cancer Cells in Surgically Resected Lung Adenocarcinomas'2011
- Author(s)
  S. Hirooka, T. Akashi, et al
- Journal Title
  
  Pathobiology
  
  Volume: 78 Pages: 10-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590309
[Journal Article] Localization of the Invadopodia-Related Proteins Actinin-1 and Cortactin to Matrix-Contact-Side Cytoplasm of Cancer Cells in Surgically Resected Lung Adenocarcinomas2011
- Author(s)
  S.Hirooka, T.Akashi, et al
- Journal Title
  
  Pathobiology
  
  Volume: 78 Issue: 1 Pages: 10-23
- DOI
  10.1159/000322734
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590309
[Journal Article] Roles of interleukin-6 and parathyroid hormone-related peptide in osteoclast formation associated with oral cancers : significance of interleukin-6 synthesized by stromal cells in response to cancer cells.2010
- Author(s)
  Kapamori K, Sakamoto K, Nakashima T, Takayanagi H, Morita K, Omura K, Nguyen ST, Miki Y, Iimura T, Himeno A, Akashi T, Yamada-Okabe H, Ogata E, Yamaguchi A
- Journal Title
  
  American Journal of Pathology
  
  Volume: 176 Pages: 968-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590309
[Journal Article] 肺大細胞神経内分泌癌(LCNEC)の切除例の検討2010
- Author(s)
  藤原直之、小島勝雄、明石巧、荒井裕国
- Journal Title
  
  日本呼吸器外科学会雑誌
  
  Volume: 24 Pages: 524-524
- Data Source
  KAKENHI-PROJECT-22590309
[Presentation] 肺腺癌における浸潤突起構成分子の細胞内局在を制御する因子の検討(会議録)2011
- Author(s)
  廣岡信一, 明石巧
- Organizer
  日本病理学会総会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-22590309
[Presentation] 肺腺癌における浸潤突起構成分子の細胞内局在を制御する因子の検討2011
- Author(s)
  廣岡信一, 明石巧, 他
- Organizer
  日本病理学会第100回総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-04-27
- Data Source
  KAKENHI-PROJECT-22590309
[Presentation] 肺腺癌におけるアクチン調節蛋白の発現異常2010
- Author(s)
  廣岡信一, 明石巧
- Organizer
  日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590309

1. FUJIWARA Naoyuki (80451912)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. 坂本啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 山口朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takumi Akashi 明石 巧

明石 巧 アカシ タクミ

AKASHI Takumi 明石 巧

Research Projects

Research Products

Co-Researchers

Study of invasion mechanism of cancer cells by proteomic analysis of Rap pathwayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study of lung cancer cell invasion mechanism through PtdIns imagingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Alteration of apical-basal polarity regulating proteins Par/Lgl/Scrib in lung adenocarcinomas and its relationship with invasion and metastasisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of Carboxypeptidase M expression profiles in patients with lung cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of molecular mechanisms of basement membrane destruction in the process of lung cancer cell invasionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒト・ラミニンA5鎖遺伝子の新規クローニングと消化器癌における発現異常の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

大腸線癌細胞の転移浸潤に及ぼす低分子量GTP結合蛋白RhOA・p21の影響Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

大腸癌培養細胞の腺管構造形成過程におけるメタロプロテアーゼの役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

大腸癌培養細胞の腺管構造形成過程におけるメタロプロテアーゼの役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Localization of cortical actin filaments and its correlation with invasion and metastasis in lung adenocarcinomas2015

Author(s)

Journal Title

Data Source

[Journal Article] 肺腺癌における皮質アクチン線維の細胞内局在と浸潤との相関2015

Author(s)

Journal Title

Data Source

[Journal Article] Propionibacterium acnes infection in glandular epithelium and stromal macrophages of the prostate with or without cancer2014

Author(s)

Journal Title

Data Source

[Journal Article] Higher serum CCL17 may be a promising predictor of acute exacerbations in chronic hypersensitivity pneumonitis2013

Author(s)

Journal Title

Data Source

[Journal Article] The expression profiles of acidic epithelial keratins in Ameloblastoma.2013

Author(s)

Journal Title

DOI

Takumi Akashi 明石巧

明石巧アカシタクミ

AKASHI Takumi 明石巧