SODA Hiroshi 早田宏

Researcher Number	60244042
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2007 – 2009: 長崎大学, 大学院・医歯薬学総合研究科, 客員研究員 2008: 長崎大学, 大学院・医歯薬総合研究科, 客員研究員 2007: Nagasaki University, 大学院・医歯薬学総合研究科, 研究員 2005 – 2006: Nagasaki University, Hospital of medicine and Dentistry, Associate Professor, 医学部・歯学部附属病院, 助教授 2005: 医学部・歯学部附属病院, 助教授 … More 2004: 長崎大学, 医学部, 助手 2004: Nagasaki University, Department of Medidne, Associate Professor, 医学部, 助教授 2004: 長崎大学, 医学部・歯学部附属病院, 講師 2002 – 2003: 長崎大学, 大学院・医歯薬学総合研究科, 助手 Less
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine Except Principal Investigator Applied pharmacology / Respiratory organ internal medicine / Laboratory medicine
Keywords	Principal Investigator 分子標的治療 / 肺癌 / apoptosis / survivin / telomerase / lung cancer / epidermal growth factor receptor / histone deacetylase / シグナル伝達系 / 薬剤耐性 … More / 粘液産生 / 上皮増殖因子受容体阻害薬 / ヒストン脱アセチル化酵素阻害薬 / アポトーシス / サバイビン / テロメラーゼ / 上皮増殖因子受容体 / ヒストン脱アセチル化酵素 / 上皮成長因子受容体阻害薬 / 肺サーファクタント蛋白 / 上皮成長因子受容体阻害 / 個別化治療 … More Except Principal Investigator 肺癌 / Colorectal cancer / Lung cancer / Irinotecan : CPT-11 / DNA-based diagnosis / Prediction for responsibility of anticancer drugs / Methylation-specific PCR / Methylation / Breast cancer resistance protein : BCRP / methylation-specific PCR (MSP) / 塩酸イリノテカンCPT-11 / methylation-specific PCR(MSP) / 大腸がん / 肺がん / 塩酸イリノテカン / 遺伝子診断 / 抗がん剤の治療効果の予測 / methylation-specific PCR / メチル化 / 乳がん耐性蛋白BCRP / Breast Cancer Resistance Protein / Telomerase / Histone Deareryinse Inhibitor / Topoisomerase Inhibitor / Drug Transporter Protpin / Lang Cancer / Cancer Chemotherapy / Drug Resistance / 茎剤輸送蛋白 / 乳癌耐性蛋白 / テロメラーゼ / ヒストン脱アセチル化阻害剤 / トポイソメラーゼ阻害薬 / 薬剤輸送蛋白 / 癌化学療法 / 薬剤耐性 / 分子標的薬 / トラフ値 / 血中濃度 / 上皮成長因子受容体阻害薬 / 分子標的治療 / 臨床薬理学 / 症例-対照研究 / 肝障害 / 遺伝子診断法 / 相関解析 / 候補遺伝子アプローチ法 / 一塩基多型(SNPs) / 抗酸化関連遺伝子 / 薬物代謝・解毒酵素遺伝子 / 副作用 / 抗結核剤 / ファーマコゲノミクス / plasma RNA / diagnostic validity / PCR / integrity / mRNA / transcriptome / survivin Less

POSSIBILITY OF PERSONALIZED TREATMENT IN PATIENTS WITH NON- SMALL CELL LUNG CANCER BY MONITERING OF SERUM CONSENTRATION OF GEFITINIB
- Principal Investigator
  
  NAKAMURA Yoichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Nagasaki University
Establishment of personalized therapy with epidermal growth factor receptor inhibitors for lung cancer based on the inhibitory effects of surfactant secretionPrincipal Investigator
- Principal Investigator
  
  SODA Hiroshi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nagasaki University
Establishment of DNA-based diagnosis for detecting tuberculosis patients with anti-tuberculosis drug-induced side effects
- Principal Investigator
  
  TSUKAMOTO Kazuhiro
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Nagasaki University
DNA-based diagnosis on responsibility for anticancer drugs by methylation-specific PCR for BCRP
- Principal Investigator
  
  TSUKAMOTO Kazuhiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Nagasaki University
Development of the effective drugs that simultaneously targeting cancer-specific proteins in lung cancerPrincipal Investigator
- Principal Investigator
  
  SODA Hiroshi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nagasaki University
SURVIVINはがんの診断・治療の普遍的な分子標的になるか
- Principal Investigator
  
  KAMIHIRA Shimeru
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagasaki University
Development of anti-lung cancer drugs overcoming drug resistance mediated by new molecules a drug efflux pump, breast cancer resistance protein (BCRP), and topoisomerase-I inhibitor
- Principal Investigator
  
  OKA Mikio
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kawasaki Medical School
  Nagasaki University

All 2010 2009 2008 2007 2006 2005 2004 2003 2002 Other

All Journal Article Presentation Book

[Book] 疾患別最新処方癌性胸膜炎2005
- Author(s)
  早田宏
- Publisher
  メジカルビュー社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Book] EBM呼吸器疾患の治療2006-2007 肺癌分子標的薬の使い方は?2005
- Author(s)
  福田実, 早田宏, 他
- Publisher
  中外医学社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Book] 肺癌の外来科学療法2005
- Author(s)
  山口博之, 早田宏, 他
- Publisher
  成人病と生活習慣病35(3)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Book] 診断と治療の最前線 : 化学療法非小細胞肺癌2005
- Author(s)
  福田実, 早田宏, 他
- Publisher
  Mebio 22(1)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Book] 癌科学療法update ABCトランスポーター2005
- Author(s)
  岡三喜男, 早田宏, 他
- Publisher
  中外医学社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Book] 抗がん剤とABCトランスポーター2005
- Author(s)
  岡三喜男, 早田宏, 他
- Publisher
  癌と化学療法32(5)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Book] EBM呼吸器疾患の治療 2006-2007(永井厚志, 吉澤靖之、編)2005
- Author(s)
  福田実, 早田宏, 岡三喜男
- Total Pages
  574
- Publisher
  中外医学社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570557
[Book] 癌化学療法Update(西條長宏, 鶴尾隆、編集)2005
- Author(s)
  岡三喜男, 福田実, 早田宏
- Total Pages
  524
- Publisher
  中外医学社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570557
[Book] 電子聴診器による肺音の解析2005
- Author(s)
  宮原末治, 早田宏, 他
- Publisher
  薬理と臨床15(5)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Book] 臨床腫瘍内科学入門化学療法の実際肺癌2005
- Author(s)
  福田実, 早田宏, 他
- Publisher
  永井書店
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Book] 疾患別最新処方肺非小細胞癌2005
- Author(s)
  早田宏
- Publisher
  メジカルビュー社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Book] 両側肺のびまん性浸潤影に続いて発祥した高齢者の血栓性血小板減少性紫斑病の1例2004
- Author(s)
  笠井尚, 早田宏, 他
- Publisher
  日本胸部臨床63(5)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Book] 呼吸器疾患の胸部単純X線写真 : 易感染性宿主の肺炎と肺真菌症・寄生虫性肺疾患2004
- Author(s)
  早田宏, 他
- Publisher
  診断と治療92(4)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Book] 基礎医学とのダイアローグ : ゲフィチニブ投与後の肺障害の発生リスク因子2004
- Author(s)
  川畑茂, 早田宏, 他
- Publisher
  THE LUNG-perspectives12(2)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Book] 副甲状腺摘出術における術中迅速intact PTH測定の有用性2004
- Author(s)
  石橋純美, 早田宏, 他
- Publisher
  医学検査53
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Book] インフルエンザ・かぜ症候群2004
- Author(s)
  山本和子, 早田宏, 他
- Publisher
  産科と婦人科71
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Interstitial pneumonia probably associated with sorafenib treatment: an alert of an adverse event2010
- Author(s)
  Ide S Soda H, Hakariya T, Takemoto S, Ishimoto H, Tomari S, Sawai T, Nagashima S, Furukawa M, Nakamura Y, Kohno S
- Journal Title
  
  Lung Cancer 67
  
  Pages: 248-250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590901
[Journal Article] Nagasaki Thoracic Oncology Group : Phase I study of vinorelbine and irinotecan in previously untreated patients with advanced non- small cell lung cancer2008
- Author(s)
  Tomonaga N, Nakamura Y, Soda H,et.al.
- Journal Title
  
  Cancer Chemothe Pharmacol 62
  
  Pages: 43-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590538
[Journal Article] Stepwise progression from ground- glass opacity towards invasive adenocarcinoma : long- term follow- up of radiological findings2008
- Author(s)
  Soda H, Nakamura Y, Nakatomi K,et.al.
- Journal Title
  
  Lung Cancer 60
  
  Pages: 298-301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590538
[Journal Article] Gefitinib increases serum concentrations of oral irinotecan and SN-38 without increasing the biliary concentration of SN-38 in rats2008
- Author(s)
  Nakamura Y, Stake K, Sano K, Ito A, Yoshikawa M, Ikegami Y, Yoshida H, Nakano H, Oka M, Sawada S, Soda H, Kohno S
- Journal Title
  
  Chemotherapy 54
  
  Pages: 485-491
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590901
[Journal Article] Stepwise progression from ground-glass opacity towards invasive adenocarcinoma: long-term follow-up of radiological findings2008
- Author(s)
  Soda H, Nakamura Y, Nakatomi K, Tomonaga N, Yamaguchi H, Nakano H, Nagashima S, Anami M, Hayashi T, Tsukamoto K, Kohno S
- Journal Title
  
  Lung Cancer 60
  
  Pages: 298-301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590901
[Journal Article] Stepwise progression from ground-glass opacity towards invasive adenocarcinoma : long-term follow-up of radiological findings2008
- Author(s)
  Soda H
- Journal Title
  
  Lung Cancer 60
  
  Pages: 298-301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590901
[Journal Article] Methylation status of breast cancer resistance protein detected by methylation- specific polymerase chain reaction analysis is correlated inversely with its expression in drug- resistant lung cancer cells2008
- Author(s)
  Nakano H, Nakamura Y, Soda H, et.al.
- Journal Title
  
  Cancer 112
  
  Pages: 1122-1130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590538
[Journal Article] Heterogeneity of epidermal growth factor receptor mutations within a mixed adenocarcinoma lung nodule2008
- Author(s)
  Nakano H, Soda H, Takasu M, Tomonaga N, Yamaguchi H, Nakatomi K, Fujino S, Hayashi T, Nakamura Y, Tsukamoto K, Kohno S
- Journal Title
  
  Lung Cance 60
  
  Pages: 136-140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590901
[Journal Article] Stepwise progression from ground-glass opacity towards invasive adenocarcinoma : long-term follow-up of radiological findings.2008
- Author(s)
  Soda H
- Journal Title
  
  Lung Cancer 60
  
  Pages: 298-301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590538
[Journal Article] Phase I study of irinotecan and gemcitabine in previously untreated patients with advanced non- small cell lung cancer2007
- Author(s)
  Takatani H, Soda H, Nakamura Y,et.al.
- Journal Title
  
  Jpn J Clin Oncol 37
  
  Pages: 353-357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590538
[Journal Article] Irinotecan and cisplatin with concurrent split- course radiotherapy in locally advanced nonsmall-cell lung cancer2007
- Author(s)
  Fukuda M, Soda H, Nakamura Y, et.al.
- Journal Title
  
  a multiinstitutional phase 2 study. Cancer 110
  
  Pages: 606-613
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590538
[Journal Article] Different epidermal growth factor receptor gene mutations in a patient with two synchronous lung cancers2007
- Author(s)
  Nakano H, Soda H, Nakamura Y, Uchida K, Takasu M, Nakatomi K, Izumikawa K, Hayashi T, Nagayasu T, Tsukamoto K, Kohno S
- Journal Title
  
  Clin Lung Cancer 8
  
  Pages: 562-564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590901
[Journal Article] Different epidermal growth factor receptor gene mutations in a patient with 2 synchronous lung cancers2007
- Author(s)
  Nakano H, Soda H, Nakamura Y, et.al.
- Journal Title
  
  Clin Lung Cancer 8
  
  Pages: 562-564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590538
[Journal Article] BCRP/ABCG2 levels account for the resistance to topoisomerase I inhibitors and reversal effects by gefitinib in non-small cell lung cancer.2006
- Author(s)
  Nagashima S, Soda H, Tsukamoto K, et al.
- Journal Title
  
  Cancer Chemother Pharmacol in press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] BCRP/ABCG2 levels account for the resistance to topoisomerase I inhibitors and reversal effects by gefitinib in non-small cell lung cancer.2006
- Author(s)
  Nagashima S, Soda H, Tsukamoto K, et al.
- Journal Title
  
  Cancer Chemother Pharmacol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] BCRP/ABCG2 levels account for the resistance to topoisomerase I inhibitors and reversal effects by gefitinib in non-small cell lung cancer.2006
- Author(s)
  Nagashima S, Soda H, Oka M, ef al.
- Journal Title
  
  Cancer Chemother Pharmacol 58
  
  Pages: 594-600
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570557
[Journal Article] Phase II study of irinotecan combined with carboplatin in previously untreated small cell lung cancer.2006
- Author(s)
  Kinoshita A, Soda H, et al.
- Journal Title
  
  Brit J Cancer in press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] A phase I study of carboplatin and etoposide for elderly (【greater than or equal】75 year-old) patients whth small-cell lung cancer.2006
- Author(s)
  Fukuda M, Soda H, et al.
- Journal Title
  
  Cancer Chemother Pharmacol in press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Long-term survival in three patients with metastatic non-small cell lung cancer treated with gefitinib.2006
- Author(s)
  Nakatomi K, Soda H, Tsukamoto K, et al.
- Journal Title
  
  Lung Cancer (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Thymic carcinoma with epidermal growth factor receptor gene mutations.2006
- Author(s)
  Yamaguchi H, Soda H, Tsukamoto K, et al.
- Journal Title
  
  Lung Cancer (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Long-term survial in three patients with metastatic non-small cell lung cancer treated with gefitinib.2006
- Author(s)
  Nakatomi K, Soda H, Tsukamoto K, et al.
- Journal Title
  
  Lung Cancer in press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Impact of p53 aberration on the progression of Adult T-cell Leukemia/Lymphoma.2006
- Author(s)
  Tawara M, Soda H, et al.
- Journal Title
  
  Cancer Lett 234(2)
  
  Pages: 249-255
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] BCRP/ABCG2 levels account for the resistance to topoisomerase I inhibitors and reversal effects by gefitinib in non-small cell lung cancer.2006
- Author(s)
  Nagashima S, Soda H, Tsukamoto K, et al.
- Journal Title
  
  Cancer Chemotherapy and Pharmacology (in press)
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Phase II study of irinotecan combined with carboplatin in previously untreated small-cell lung cancer.2006
- Author(s)
  Kinoshita A, Soda H, Oka M, ef al.
- Journal Title
  
  British Journal of Cancer 94
  
  Pages: 1267-1271
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570557
[Journal Article] Tyhmic carcinoma with epidermal growth factor receptor gene mutations.2006
- Author(s)
  Yamaguchi H, Soda H, Tsukamoto K, et al.
- Journal Title
  
  Lung Cancer in press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Impact of p53 aberration on the progression of adult T-cell leukemia/lymphoma.2006
- Author(s)
  Tawara M, Soda H, et al.
- Journal Title
  
  Cancer Lett 234(2)
  
  Pages: 249-255
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Phase II study of irinotecan combined with carboplatin in previously untreated small cell lung cancer.2006
- Author(s)
  Kinoshita A, Soda H, et al.
- Journal Title
  
  Brit J Cancer (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] A phase I study of carboplatin and etoposide for elderly (【greater than or equal】75 year-old) patients with small-cell lung cancer.2006
- Author(s)
  Fukuda M, Soda H, et al.
- Journal Title
  
  Cancer Chemother Pharmacol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Gefitinib ("Iressa", ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, reverses breast cancer resistance protein/ABCG2-mediated drug resistance.2005
- Author(s)
  Nakamura Y, Oka M, Soda H, ef al.
- Journal Title
  
  Cancer Research 65
  
  Pages: 1541-1546
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570557
[Journal Article] Novel effects of gefitinib on mucin production in bronchioloalveolar carcinoma ; two case reports.2005
- Author(s)
  Kitazaki T, Soda H, et al.
- Journal Title
  
  Lung Cancer 49(1)
  
  Pages: 125-128
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Outpatient chemotherapy in lung cancers.[in Japanese}2005
- Author(s)
  Yamaguchi H, Soda H, et al.
- Journal Title
  
  Adult-onset diseases & Lifestyle-related illness 35(3)
  
  Pages: 304-309
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Gefitinib ("Iressa", ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, reverses breast cancer resistance protein/ABCG2-mediated drug resistance.2005
- Author(s)
  Nakamura Y, Soda H, et al.
- Journal Title
  
  Cancer Res 65(4)
  
  Pages: 1541-1546
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Chemotherapy for non-small cell lung cancer.[in Japanese]2005
- Author(s)
  Fukuda M, Soda H, et al.
- Journal Title
  
  Mebio 22(1)
  
  Pages: 44-53
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Novel effects of gefitinib on mucin production in bronchioloalveolar carcinoma; two case reports.2005
- Author(s)
  Kitazaki T, Soda H, et al.
- Journal Title
  
  Lung Cancer 49(1)
  
  Pages: 125-128
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Carcinomatous pleurisy.[in Japanese]2005
- Author(s)
  Soda H.
- Journal Title
  
  Medical View
  
  Pages: 238-239
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Chronic necrotizing pulmonary aspergillosis following cryptococcal infection of the lung.2005
- Author(s)
  Kitazaki T, Soda H, et al.
- Journal Title
  
  Scand J Infect Dis 37(5)
  
  Pages: 393-395
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] A long-term survival patient with metastatic brain tumor by Gamma-knife stereotactic radiosurgery.[in Japanese]2005
- Author(s)
  Kakeya H, Soda H, et al.
- Journal Title
  
  J Jpn Res Society 43(12)
  
  Pages: 736-740
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Gefitinib, an EGFR tyrosine kinase inhibitor, directly inhibits the function of P-glycoprotein in multidrug resistant cancer cells.2005
- Author(s)
  Kitazaki T, Oka M, Soda H, ef al.
- Journal Title
  
  Lung Cancer 49
  
  Pages: 337-347
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570557
[Journal Article] Gefitinib ("Iressa", ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, reverses breast cancer resistance protein /ABCG2-mediated drug resistance.2005
- Author(s)
  Nakamura Y, Soda H, et al.
- Journal Title
  
  Cancer Res 65(4)
  
  Pages: 1541-1546
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] 抗がん剤とABCトランスポーター2005
- Author(s)
  岡三喜男, 福田実, 早田宏
- Journal Title
  
  癌と化学療法 32
  
  Pages: 585-592
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570557
[Journal Article] 血清可溶性インターロイキン2受容体の上昇を認めた縦隔原発大細胞型B細胞性リンパ種の2例2005
- Author(s)
  中富克己, 早田宏, 他
- Journal Title
  
  長崎医学会雑誌 80(1)
  
  Pages: 18-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Non-small cell lung cancer.[in Japanese]2005
- Author(s)
  Soda H.
- Journal Title
  
  Medical View
  
  Pages: 240-241
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Pulmonary sound analysis by electronic stethoscope.[in Japanese]2005
- Author(s)
  Miyahara S, Soda H, et al.
- Journal Title
  
  Clin Pharmacol 15(5)
  
  Pages: 511-518
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Gefitinib, an EGFR tyrosine kinase inhibitor, directly inhibits the function of P-glycoprotein in multidrug resistant cancer cells.2005
- Author(s)
  Kitazaki T, Soda H, et al.
- Journal Title
  
  Lung Cancer 49(3)
  
  Pages: 337-343
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] ABC transporters.[in Japanese]2005
- Author(s)
  Oka M, Soda H, et al.
- Journal Title
  
  Tyugai Igakusya
  
  Pages: 68-74
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Lung cancer in the practical side of chemotherapy.[in Japanese]2005
- Author(s)
  Fukuda M, Soda H, et al.
- Journal Title
  
  Nagai Shoten
  
  Pages: 232-237
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] 肺癌術後脳転移に対してGamma-knife stereotactic radiosurgeryを繰り返して長期生存が得られた1例2005
- Author(s)
  掛屋弘, 早田宏, 他
- Journal Title
  
  日本呼吸会誌 43(12)
  
  Pages: 736-740
- NAID
  10018364929
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Gefitinib inhibits MUC5AC synthesis in mucin-secreting non-small cell lung cancer cells.2005
- Author(s)
  Kitazaki T, Soda H, et al.
- Journal Title
  
  Lung Cancer 50(1)
  
  Pages: 19-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Two patients with mediastinal diffuse large B-cell lymphoma accompanied with elevation of soluble interleukin 2 receptor in sera.[in Japanese]2005
- Author(s)
  Nakatomi K, Soda H, et al.
- Journal Title
  
  Act Med Nagasaki 80(1)
  
  Pages: 18-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Gefitinib, an EGFR throsine kinase inhibitor, directly inhibits the function of P-glycoprotein in multidrug resistant cancer cells.2005
- Author(s)
  Kitazaki T, Soda H, et al.
- Journal Title
  
  Lung Cancer 49(3)
  
  Pages: 337-343
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] How to use of molecular target anticancer drugs in lung cancer.[in Japanese]2005
- Author(s)
  Fukuda M, Soda H, et al.
- Journal Title
  
  Tyugai Igakusya
  
  Pages: 446-457
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Anticancer drugs and ABC transporters.[in Japanese]2005
- Author(s)
  Oka M, Soda H, et al.
- Journal Title
  
  Jpn J Cancer Chemother 32(5)
  
  Pages: 585-592
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Gefitinib ("Iressa", ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, reverses breast cancer resistance protein/ABCG2-mediated drug resistance.2005
- Author(s)
  Nakamura Y, Oka M, Soda H, et al.
- Journal Title
  
  Cancer Research 64(4)
  
  Pages: 1541-1546
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Influenza and common cold.[in Japanese]2004
- Author(s)
  Yamamoto K, Soda H, et al.
- Journal Title
  
  Obstet Gynecol 71
  
  Pages: 1425-1431
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] High-risk populations for nasal carriage of methicillin-resistant Staphylococcus aureus.2004
- Author(s)
  Fukuda M, Soda H, et al.
- Journal Title
  
  J Infect Chemother 10(3)
  
  Pages: 189-191
- NAID
  10013331695
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] An availability of the measurement of intact PTH on enucleation of parathyroid glands.[in Japanese]2004
- Author(s)
  Ishibashi M, Soda H, et al.
- Journal Title
  
  Medical examination 53
  
  Pages: 1355-1359
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] The histone deacetylase inhibitor FR901228 induces caspase-dependent apoptosis via the mitochondrial pathway in small cell lung cancer cells.2004
- Author(s)
  Doi S, Soda H, et al.
- Journal Title
  
  Mol Cancer Ther 3(11)
  
  Pages: 1397-1402
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Novel camptothecin analogues that circumvent ABCG2-associated drug resistance in human tumor cells.2004
- Author(s)
  Yoshikawa M, Soda H, et al.
- Journal Title
  
  Int J Cancer 110(6)
  
  Pages: 921-927
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Opportunistic pneumoniae and parasitic lung diseases.[in Japanese]2004
- Author(s)
  Soda H, et al.
- Journal Title
  
  Diagnosis and Treatment 92(4)
  
  Pages: 595-602
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] The histone deacetylase inhibitor FR901228 induces caspase-dependent apoptosis via the mitochondrial pathway in small cell lung cancer cells.2004
- Author(s)
  Doi S, Soda H, Oka M, ef al.
- Journal Title
  
  Molecular Cancer Therapeutics 3
  
  Pages: 1397-1402
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570557
[Journal Article] Reversal of breast cancer resistance protein (BCRP/ABCG2)-mediated drug resistance by novobiocin, acoumermycin antibiotic.2004
- Author(s)
  Shiozawa K, Oka M, Soda H, ef al.
- Journal Title
  
  International Journal of Cancer 108
  
  Pages: 146-151
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570557
[Journal Article] Phase II study of irinotecan combined with carboplatin in previously untreated non-small-cell lung cancer.2004
- Author(s)
  Fukuda M, Oka M, Soda H, ef al.
- Journal Title
  
  Cancer Chemotherapy and Pharmacology 54
  
  Pages: 573-577
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570557
[Journal Article] Autoimmunity to heat shock protein 40 in ulcerative colitis.2004
- Author(s)
  Sato S, Soda H, et al.
- Journal Title
  
  J Int Med Res 32(2)
  
  Pages: 141-148
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Reversal of breast cancer resistance protein (BCRP/ABCG2)-mediated drug resistance by novobiocin, a coumermycin antibiotic.2004
- Author(s)
  Shiozawa K, Soda H, et al.
- Journal Title
  
  Int J Cancer 108(1)
  
  Pages: 146-151
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Phase II study of irinotecan combined with carboplatin in previously untreated non-small-cell lung cancer.2004
- Author(s)
  Fukuda M, Soda H, et al.
- Journal Title
  
  Cancer Chemother Pharmacol 54(6)
  
  Pages: 573-577
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] The histone deacetylase inhibitor FR901228 induces caspase-dependent apop2004
- Author(s)
  Doi S, Soda H, Oka M, et al.
- Journal Title
  
  Molecular Cancer Therapeutics 3
  
  Pages: 1397-1402
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570557
[Journal Article] Risk factors of gefitinib-induced lung injuries.[in Japanese]2004
- Author(s)
  Kawabata S, Soda H, et al.
- Journal Title
  
  THE LUNG-perspectives 12(2)
  
  Pages: 195-200
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] The histone deacetylase inhibitor FR901128 induces caspase-dependent apoptosis via the mitochondrial pathway in small cell lung cancer cells.2004
- Author(s)
  Doi S, Soda H, et al.
- Journal Title
  
  Mol Cancer Ther 3(11)
  
  Pages: 1397-1402
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Clinical relevance of survivin as a biomarker in neoplasms, especially in adult T-cell leukemias and acute leukemias.2004
- Author(s)
  Sugahara K, Soda H, et al.
- Journal Title
  
  Int J Hematol 80(1)
  
  Pages: 52-58
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] A senior case with thrombotic thrombocytopenic purpura followed by bilateral diffuse infiltration shadow.[in Japanese]2004
- Author(s)
  Kasai N, Soda H, et al.
- Journal Title
  
  Jpn J Chest Dis 63(5)
  
  Pages: 488-494
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590437
[Journal Article] Antiproliferative effects of the histone deacetylase inhibitor FR901228 on small-cell lung cancer lines and drug-resistant sublines.2003
- Author(s)
  Tsurutani J, Oka M, Soda H, ef al.
- Journal Title
  
  International Journal of Cancer 104
  
  Pages: 238-242
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570557
[Journal Article] Antiproliferative effects of the histone deacetylase inhibitor FR901228 on small-cell lung cancer lines and drug-resistant sublines2003
- Author(s)
  Tsurutani J, Soda H, Oka M, et al.
- Journal Title
  
  International Journal of Cancer 104
  
  Pages: 238-242
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570557
[Journal Article] Expression and functional analyses of breast cancer resistance protein in lung cancer.2003
- Author(s)
  Kawabata S, Oka M, Soda H, ef al.
- Journal Title
  
  Clinical Cancer Research 9
  
  Pages: 3052-3057
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570557
[Journal Article] Phase I study of irinotecan and cisplatin with concurrent split-course radiotherapy in limited-disease small-cell lung cancer.2002
- Author(s)
  Oka M, Soda H, ef al.
- Journal Title
  
  European Journal of Cancer 38
  
  Pages: 1998-2004
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570557
[Journal Article] Phase I and pharmacokinetic study of paclitaxel and irinotecan for patients with2002
- Author(s)
  Kasai T, Oka M, Soda H, et al.
- Journal Title
  
  European Journal of Cancer 38
  
  Pages: 1871-1878
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570557
[Journal Article] Phase I and pharmacokinetic study of paclitaxel and irinotecan for patients with advanced non-small cell lung cancer.2002
- Author(s)
  Kasai T, Oka M, Soda H, et al.
- Journal Title
  
  European Journal of Cancer 38
  
  Pages: 1871-1878
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570557
[Journal Article] Histone deacetylase inhibitors suppress telomerase reverse transcriptase mRNA expression in prostate cancer cells.2002
- Author(s)
  Suenaga M, Soda H, Oka M, ef al.
- Journal Title
  
  International Journal of Cancer 97
  
  Pages: 621-625
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570557
[Journal Article] Phase I study of irinotecan and cisplatin with concurrent split-course radiotherapy2002
- Author(s)
  Oka M, Fukuda M, Soda H, et al.
- Journal Title
  
  European Journal of Cancer 38
  
  Pages: 1998-2004
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570557
[Journal Article] Histone deacetylase inhibitors suppress telomerase reverse transcriptase mRNA2002
- Author(s)
  Suenaga M, Soda H, Oka M, et al.
- Journal Title
  
  International Journal of Cancer 97
  
  Pages: 621-625
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570557
[Journal Article] Serum levels of surfactant protein D predict the anti-tumor activity of gefitinib in patients with advanced non-small cell lung cancer
- Author(s)
  Yamaguchi H, Soda H, Nakamura Y, Takasu M, Tomonaga N, Nakano H, Doi S, Nakatomi K, Nagashima S, Takatani H, Fukuda M, Hayashi T, Tsukamoto K, Kohno S
- Journal Title
  
  Cancer Chemother Pharmacol (in press)
- NAID
  120006984543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590901
[Presentation] 肺癌・胸膜中皮腫の治療戦略 : 化学療法2009
- Author(s)
  早田宏
- Organizer
  第35回肺癌診断会(日本肺癌学会主催)
- Place of Presentation
  佐世保市
- Year and Date
  2009-06-26
- Data Source
  KAKENHI-PROJECT-19590901
[Presentation] 当院で経験した薬剤性肺障害の検討2009
- Author(s)
  石本裕士, 坂本憲穂, 原信太郎, 井手昇太郎, 竹本慎之輔, 泊慎也, 長島聖二, 澤井豊光, 早田宏, , 迎寛, 河野茂
- Organizer
  第49回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590901
[Presentation] シンポジウム:肺癌・胸膜中皮腫の治療戦略, 化学療法2009
- Author(s)
  早田宏
- Organizer
  第35回肺癌診断会(日本肺癌学会主催)
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-19590901
[Presentation] Gefitinib効果予測因子としての血清SP-Dの検討2008
- Author(s)
  山口博之, 中村洋一, 朝永七枝, 中野浩文, 土井誠志, 中富克己, 早田宏, 塚元和弘, 河野茂
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19590901
[Presentation] Pharmacokinetics of gefitinib predicts the antitumor activity for NSCLC patients : adding the analysis of EGFR-mutations2008
- Author(s)
  中村、佐野、早田ら
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19590538
[Presentation] ゲフィチニブ血中濃度の肺癌患者における抗腫瘍活性に与える影響EGFR遺伝子解析の追加報2008
- Author(s)
  中村洋一, 佐野和美, 早田宏, 塚元和弘, 高谷洋長島聖二, 福田実, 山口博之, 土井誠志, 中富克己, 岡三喜男, 河野茂
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19590901
[Presentation] 進行非小細胞肺癌に対するirinotecan/paclitaxelおよびirinotecan/gemcitabineの無作為化第II相試験2007
- Author(s)
  早田宏
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜市
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19590901
[Presentation] Pharmacokinetics of gefitinib predicts the antitumor activity for advanced non-small cell lung cancer2007
- Author(s)
  Iida T, Nakamura Y, Fukuda M, Takatani H, Nagashima S, Kinoshita A, Fukuda M, Soda H
- Organizer
  12th World Conference on Lung Cancer
- Place of Presentation
  Seoul
- Data Source
  KAKENHI-PROJECT-19590901
[Presentation] Gefitinib効果予測因子としての血清SP-Dの検討2007
- Author(s)
  山口博之, 中村洋一, 朝永七枝, 中野浩文, 中富克己, 早田宏, 河野茂
- Organizer
  第48回日本肺癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19590901
[Presentation] Pharmacokinetics of gefitinib predicts the antitumor activity for advanced non- small cell lung cancer (NSCLC)
- Author(s)
  Iida T, Nakamura Y, Soda H, et.al.
- Organizer
  12th World Conference on Lung Cancer
- Place of Presentation
  Seoul
- Data Source
  KAKENHI-PROJECT-19590538

1. NAKAMURA Yoichi (20432974)

# of Collaborated Projects: 3 results

# of Collaborated Products: 18 results
2. KAMIHIRA Shimeru (80108290)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. TSUKAMOTO Kazuhiro (30253305)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. YANAGIHARA Katsunori (40315239)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. INAMINE Tatsuo (00549628)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. OKA Mikio (40223995)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
7. 山田恭暉 (60145232)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HIGUCHIHI Denori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TAHARA Naoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MAWATARI Tsutomu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. YOSHIDA Mariko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. FUJIE Syoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. NAKAURA Ayano

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SODA Hiroshi 早田 宏

Research Projects

Research Products

Co-Researchers

POSSIBILITY OF PERSONALIZED TREATMENT IN PATIENTS WITH NON- SMALL CELL LUNG CANCER BY MONITERING OF SERUM CONSENTRATION OF GEFITINIB

Principal Investigator

Project Period (FY)

Research Category

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Establishment of personalized therapy with epidermal growth factor receptor inhibitors for lung cancer based on the inhibitory effects of surfactant secretionPrincipal Investigator

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Establishment of DNA-based diagnosis for detecting tuberculosis patients with anti-tuberculosis drug-induced side effects

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DNA-based diagnosis on responsibility for anticancer drugs by methylation-specific PCR for BCRP

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Development of the effective drugs that simultaneously targeting cancer-specific proteins in lung cancerPrincipal Investigator

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SURVIVINはがんの診断・治療の普遍的な分子標的になるか

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Development of anti-lung cancer drugs overcoming drug resistance mediated by new molecules a drug efflux pump, breast cancer resistance protein (BCRP), and topoisomerase-I inhibitor

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[Book] 疾患別最新処方 癌性胸膜炎2005

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[Book] EBM呼吸器疾患の治療2006-2007 肺癌 分子標的薬の使い方は?2005

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Description

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[Book] 肺癌の外来科学療法2005

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Description

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[Book] 診断と治療の最前線 : 化学療法 非小細胞肺癌2005

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[Book] 癌科学療法update ABCトランスポーター2005

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[Book] 抗がん剤とABCトランスポーター2005

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[Book] EBM呼吸器疾患の治療 2006-2007(永井厚志, 吉澤靖之、編)2005

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SODA Hiroshi 早田宏

[Book] 疾患別最新処方癌性胸膜炎2005

[Book] EBM呼吸器疾患の治療2006-2007 肺癌分子標的薬の使い方は?2005

[Book] 診断と治療の最前線 : 化学療法非小細胞肺癌2005

[Book] 臨床腫瘍内科学入門化学療法の実際肺癌2005

[Book] 疾患別最新処方肺非小細胞癌2005