Fujinaga Yukako 藤永由佳子

… Alternative Names

藤永由佳子フジナガユカコ

FUJINAGA Yukako 藤永由佳子

Less

Researcher Number	60252954
Other IDs
External Links
Affiliation (Current)	2025: 金沢大学, 医学系, 教授
Affiliation (based on the past Project Information) *help	2018 – 2024: 金沢大学, 医学系, 教授 2011: Osaka University, 微生物病研究所, その他 2009 – 2010: Osaka University, 微生物病研究所, 特任准教授 2007: Osaka University, Research Institute for Microbial Diseases, SA, Associate Professor 2006: 阪大, 微生物病研究所 … More 2005 – 2006: Osaka University, Institute for Microbial Diseases, SA Associate Professor 2004: 大阪大学, 微生物病研究所, 特任助手 2002 – 2003: 岡山大学, 大学院・医歯学総合研究科, 助手 1993 – 2000: 岡山大学, 医学部, 助手 1994: 岡山大学, 医学部・, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 49050:Bacteriology-related / Bacteriology (including Mycology) / Bacteriology (including Mycology) / Biological Sciences / Cell biology / Urology Except Principal Investigator Bacteriology (including Mycology) / Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator tight junction / ボツリヌス毒素 / Clostridium botulinum / ボツリヌス菌 / 感染防御 / 感染実験 / 芽胞 / 腸内細菌 / C. botulinum / botulinum toxin … More / TER / Biofilm / 上皮細胞 / 細菌 / 微生物 / neurotoxin / C.botulinum / PCR / 感染毒素型 / ボツリヌス症 / Clostridia / クロストリジウム属 / 細菌毒素 / Clostridium / ボツリヌス / 病原性 / botulinum / hemagglutinin / botulinum neurotoxin / glycoprotein / cell to cell function / epithelial cell / 膜タンパク質 / 糖タンパク / 細胞接着 / Antimicrobial agent / Exopolysaccharide / P.aeruginosa / Confocal laser scanning microscope / Urinary truct infection / 難治性感染症 / 菌体外多糖 / 化学療法 / 菌対外多糖 / 緑膿菌 / 共焦点レーザー走査顕微鏡 / 尿路感染症 / バイオフィルム / 上皮細胞バリア / 毒素 / 生理活性 / バリア / Caco-2 / paracellular / transcytosis / 腸管上皮細胞 / 経鼻接種 / ワクチン / toxin gene / botulism … More Except Principal Investigator Hemagglutinin / ボツリヌス毒素 / ボツリヌス菌 / Receptor / Botulinum toxin / 赤血球凝集素 / Neurotoxin / Siglec family / β-trefoil domain / Binding / Progenitor toxin / Clostridium botulinum / シアル酸 / レセプター / 腸炎 / 肝癌 / 腸内細菌叢 / 腸内細菌 / Botulinum Toxin / Sialic acid / Lactose / Hemaggultinin / Hemag glutinin / Neuro toxin / Monoclonal antibody / Ga1β1-4 G1cNac / Sialy lactose / Salic acid / Haemagglutinin / ムチン蛋白質 / モノクローナル抗体 / Galβ1-4GlcNAc / シアリルラクトース / sialic acid / receptor / Botulism / ボツリヌス中毒 / nontoxic component / botulinum toxin / C.botulinum / ポツリヌス毒素 / ポツリヌス菌 / 無毒成分 / ケミカルメディエーター / ATP / 初代神経細胞 / NG-108細胞 Less

共生細菌による病原性クロストリジウム属菌の腸管感染制御とその機構の解明Principal Investigator
- Principal Investigator
  
  藤永由佳子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Kanazawa University
In vivo analysis of gut microbiota which prevents the intestinal botulismPrincipal Investigator
- Principal Investigator
  
  Fujinaga Yukako
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Kanazawa University
Investigation of genes of unknouwn function exist in the toxin gene related region of C. botulinumPrincipal Investigator
- Principal Investigator
  
  Fujinaga Yukako
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Kanazawa University
Roles of Enterococcus in carcinogenesis and inflammation
- Principal Investigator
  
  IIDA Noriho
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kanazawa University
ボツリヌスHAの細胞間バリア破壊作用の分子機構と病態における意義についてPrincipal Investigator
- Principal Investigator
  
  藤永由佳子
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
ボツリヌスHAと腸管上皮細胞の相互作用の解明Principal Investigator
- Principal Investigator
  
  藤永由佳子
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Osaka University
ボツリヌス神経毒素複合体の宿主腸管上皮細胞バリア通過機構の解明Principal Investigator
- Principal Investigator
  
  藤永由佳子
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Research on the mechanism of tight jundan regulafion by using botulinum toxir complexPrincipal Investigator
- Principal Investigator
  
  FUJINAGA Yukako
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Osaka University
Search for Clostridium botulinum derived Substance that has a function to disrupt the intestinal epithelial barrier.Principal Investigator
- Principal Investigator
  
  FUJINAGA Yukako
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Osaka University
Analysis of tertial structure and function of non-toxic components associating with Clostridium botulinum neurotoxins.
- Principal Investigator
  
  OGUMA Keiji
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  OKAYAMA UNIVERSITY
Analysis of absorption of Clostridium botulinum toxins from the small infestine
- Principal Investigator
  
  OGUMA Keiji
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Okayama University
Analysis of absorption of Clostridium botulinum neurotoxin-nontoxic component complex from the small intestine.
- Principal Investigator
  
  OGUMA Keiji
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Okayama University
牛のボツリヌスC型、D型中毒の両方に効果のあるリコンビナントワクチンの作製Principal Investigator
- Principal Investigator
  
  藤永由佳子
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Okayama University
ボツリヌスC型、D型菌の神経毒素遺伝子およびその発現制御機構の分子生物学的解析Principal Investigator
- Principal Investigator
  
  藤永由佳子
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Okayama University
Structure and function of the nontoxic components of Clostridium botulinum progenitor toxins.
- Principal Investigator
  
  OGUMA Keiji
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Okayama University
ボツリヌス毒素の作用機構の解明
- Principal Investigator
  
  OGUMA Keiji
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Okayama University
PCR法を用いたボツリヌス菌毒素の新しい検出法の確立と基礎的研究Principal Investigator
- Principal Investigator
  
  藤永由佳子
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Okayama University
Analysis of Biofilm Disease as Cryptic Bacterial Infection and Study for Medical TreatmentPrincipal Investigator
- Principal Investigator
  
  FUJINAGA Yukako, 公文裕巳
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Okayama University

All 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

[Book] 第29回阿蘇シンポジウム記録感染防御のBird's-eye view[ボツリヌス毒素複合体と宿主腸管上皮細胞]2006
- Author(s)
  藤永由佳子
- Publisher
  南山堂
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570178
[Journal Article] Botulinum HA disrupts the intercellular epithelial barrier by directly binding E-cadherin.2010
- Author(s)
  Sugawara Y., Matsumura T, Takegahara, Y., Jin Y., Tsukasaki Y., Takeichi M., Fujinaga, Y
- Journal Title
  
  J.Cell Biol.
  
  Volume: 189 Pages: 691-700
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390128
[Journal Article] Interaction of botulinum toxin with the epithelial barrier.2010
- Author(s)
  Fujinaga Y.
- Journal Title
  
  Journal of Biomedicine and Biotechnology 2010
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21022027
[Journal Article] Interaction of botulinum toxin with the epithelial barrier.2010
- Author(s)
  Fujinaga Y.
- Journal Title
  
  Journal of Biomedicine and Biotechnology
  
  Volume: 2010
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21022027
[Journal Article] Interaction of botulinum toxin with the epithelial barrier.2010
- Author(s)
  Fujinaga Y.
- Journal Title
  
  Journal of Biomedicine and Biotechnology 2010(Article ID 974943, 9 pages)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390128
[Journal Article] Interaction of botulinum toxin with the epithelial barrier.2010
- Author(s)
  Fujinaga, Y.
- Journal Title
  
  Journal of Biomedicine and Biotechnology
  
  Volume: 2010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390128
[Journal Article] Botulinum HA disrupts the intercellular epithelial barrier by directly binding E-cadherin.2010
- Author(s)
  Sugawara Y., Matsumura T, Takegahara, Y., Jin Y., Tsukasaki Y., Takeichi M., Fujinaga, Y
- Journal Title
  
  J.Cell Biol.
  
  Volume: 189 Pages: 691-700
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21022027
[Journal Article] ボツリヌス毒素と腸管上皮細胞バリア破壊2009
- Author(s)
  藤永由佳子
- Journal Title
  
  化学療法の領域 25
  
  Pages: 745-754
- Data Source
  KAKENHI-PROJECT-21390128
[Journal Article] 水際の攻防～ボツリヌス毒素vs腸管上皮細胞バリア2009
- Author(s)
  藤永由佳子
- Journal Title
  
  細胞の化学遺伝 63
  
  Pages: 20-25
- Data Source
  KAKENHI-PROJECT-21390128
[Journal Article] Molecular characterization of binding subcomponents of Clostridium botulinum type C progenitor toxin for intestinal epithelial cells and erythrocytes.2009
- Author(s)
  Y. Fujinaga, et. al.
- Journal Title
  
  Microbiology 150
  
  Pages: 1529-1538
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590359
[Journal Article] A novel function of botulinum toxin-associated proteins : HA proteins disrunt intestinal epithelial barrier to increase toxin absorption.2009
- Author(s)
  Fujinaga, Y., et al.
- Journal Title
  
  Toxicon 54
  
  Pages: 583-586
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21022027
[Journal Article] ボツリヌス毒素と腸管上皮細胞バリア破壊2009
- Author(s)
  藤永由佳子
- Journal Title
  
  化学療法の領域 25
  
  Pages: 745-754
- Data Source
  KAKENHI-PUBLICLY-21022027
[Journal Article] 水際の攻防～ボツリヌス毒素vs腸管上皮細胞バリア2009
- Author(s)
  藤永由佳子
- Journal Title
  
  細胞の化学遺伝 63
  
  Pages: 20-25
- Data Source
  KAKENHI-PUBLICLY-21022027
[Journal Article] A novel function of botulinum toxin-associated proteins : HA proteins disrupt intestinal epithelial barrier to increase toxin absorption.2009
- Author(s)
  Fujinaga, Y., et al.
- Journal Title
  
  Toxicon 54
  
  Pages: 583-586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390128
[Journal Article] Humanmilk STgA binds to botulinum type B 16S toxin and Timits toxin adherence on T84 cells.2007
- Author(s)
  T. Matsumura, Y. Fujinaga, Et. al.
- Journal Title
  
  Biochemical and Biophysical Research Communications 352
  
  Pages: 867-872
- Data Source
  KAKENHI-PROJECT-18570178
[Journal Article] 細菌毒素の細胞内輸送機構〜みえてきた細菌毒素が持つ巧妙な戦略〜2006
- Author(s)
  藤永由佳子
- Journal Title
  
  化学療法の領域 22.2
  
  Pages: 231-237
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570178
[Journal Article] Fujinaga. Transport of bacterial toxins into target cells : Pathways followed by cholera toxin and botulinum progenitor toxin2006
- Author(s)
  Y., Fujinaga
- Journal Title
  
  J.Biochem (Tokyo) 140
  
  Pages: 155-160
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570178
[Journal Article] Transport of bacterial toxins into target cells : pathway tollowed by cholera toxin and botulinum progenitor toxin2006
- Author(s)
  Fujinaga Y
- Journal Title
  
  J. Biochem (in press)
- Data Source
  KAKENHI-PROJECT-16590359
[Journal Article] Interactions of botulinum progenitor toxin and cholera toxin with host intestinal epithelial cells.2006
- Author(s)
  Fujinaga Y
- Journal Title
  
  J. Toxicol. Toxin Rev (in press)
- Data Source
  KAKENHI-PROJECT-16590359
[Journal Article] Transport of bacterial toxins into target cells:Pathways followed by cholera toxin and botulinum progenitor toxin.2006
- Author(s)
  Y. Fujinaga
- Journal Title
  
  J. Biochem(Tokyo) 140
  
  Pages: 155-160
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590359
[Journal Article] 細菌毒素の細胞内輸送機構-みえてきた細菌毒素が持つ巧妙な戦略-2006
- Author(s)
  藤永由佳子
- Journal Title
  
  化学療法の領域 22.2
  
  Pages: 231-237
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590359
[Journal Article] Interactions of botulinum progenitor toxin and cholera toxin with host intestinal epithelial cells.2006
- Author(s)
  Y-Fujinaga
- Journal Title
  
  J. Toxicol. Toxin Rev. 25
  
  Pages: 47-59
- Data Source
  KAKENHI-PROJECT-18570178
[Journal Article] Interactions of botulinum progenitor toxin and cholera toxin with host intestinal epithelial cells.2006
- Author(s)
  Y. Fujinaga
- Journal Title
  
  J. Toxicol. Toxin Rev. 25
  
  Pages: 47-59
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590359
[Journal Article] Interactions of botulinum progenitor toxin and cholera toxin with host intestinal epithelial cells2006
- Author(s)
  Fujinaga, Y
- Journal Title
  
  J. Toxicol.Toxin Rev 25
  
  Pages: 47-59
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570178
[Journal Article] Interactions of botulinum progenitor toxin and cholera toxin with host intestinal epithelial cells.2006
- Author(s)
  Y. Fujinaga
- Journal Title
  
  J. Toxicol. Toxin Rev. 25
  
  Pages: 47-59
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570178
[Journal Article] 細菌毒素の細胞内輸送機構-みえてきた細菌毒素が持つ巧妙な戦略-2006
- Author(s)
  藤永由佳子
- Journal Title
  
  化学療法の領域 22・2
  
  Pages: 231-237
- Data Source
  KAKENHI-PROJECT-16590359
[Journal Article] Transport of bacterial toxins into target cells: Pathways followed by cholera toxin and botulinum progenitor toxin.2006
- Author(s)
  Y. Fujinaga
- Journal Title
  
  J. Biochem(Tokyo) 140
  
  Pages: 155-160
- NAID
  10018842667
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570178
[Journal Article] Transport og\f bacterialtoxins into target cells: Pathways followed by cholera toxin and botulinum progenitor toxin.2006
- Author(s)
  Y-Fujinaga
- Journal Title
  
  J. Biochem (Tokyo) 140
  
  Pages: 155-160
- Data Source
  KAKENHI-PROJECT-18570178
[Journal Article] コレラ毒素の細胞内輸送2005
- Author(s)
  藤永由佳子
- Journal Title
  
  最新医学 60.6
  
  Pages: 1229-1233
- NAID
  40006794031
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590359
[Journal Article] コレラ毒素の細胞内輸送2005
- Author(s)
  藤永由佳子
- Journal Title
  
  最新医学 60・6
  
  Pages: 1229-1233
- NAID
  40006794031
- Data Source
  KAKENHI-PROJECT-16590359
[Journal Article] Characterization of the interaction between subunits of the botulinum toxin complex produced by serotype D through through tryptic susceptibility of the isolated components and complex forms.2005
- Author(s)
  Suzuki T., Watanabe T., Mutoh S., Hasegawa K., Kouguchi H., Sagane Y., Fujinaga Y., Oguma K., Ohyama T.
- Journal Title
  
  Microbiology 151
  
  Pages: 1475-1483
- Data Source
  KAKENHI-PROJECT-16590359
[Journal Article] Molecular characterization of binding subcomponents of Clostridium botulinum type C progenitor toxin for intestinal epithelial cells and erythrocytes.2004
- Author(s)
  Fujinaga Y, et. al.
- Journal Title
  
  Microbiology 150
  
  Pages: 1529-1538
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590359
[Journal Article] ポツリヌス毒素複合体と宿主腸管上皮細胞
- Author(s)
  藤永由佳子
- Journal Title
  
  阿蘇シンポジウムモノグラフ (in press)
  
  Pages: 2006-2006
- Data Source
  KAKENHI-PROJECT-16590359
[Presentation] Reconstitution and dissection of epithelial barrier disrupting activity of type B botulinum HA.2010
- Author(s)
  竹ヶ原夕紀、菅原庸、松村拓大、藤永由佳子
- Organizer
  第83回日本細菌学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PUBLICLY-21022027
[Presentation] ボツリヌス毒素複合体成分とE-cadherinの結合による上皮細胞間バリア破壊と毒素の腸管吸収2010
- Author(s)
  藤永由佳子、菅原庸、松村拓大
- Organizer
  第33回日本分子生物学会年回・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-21022027
[Presentation] Development of human monoclonal antibodies against type Abotulinum neurotoxin.2010
- Author(s)
  Matsumura T, Du A, Sugawara Y, Kohda T, Takahashi M, Kozaki S, Ikuta K, Fujinaga Y.
- Organizer
  47^<th> IBRCC 2010, Intergency botulinum research coordinating committee meeting
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PUBLICLY-21022027
[Presentation] Botulinum hemagglutinin targets E-cadherin to disrupt the intercellular epithelial barrier.2010
- Author(s)
  Sugawara Y, Matsumura T, Takegahara T, Jin Y, Fujinaga Y.
- Organizer
  The Awaji International Forum on Infection and Immunity
- Place of Presentation
  Awaji Island, Japan
- Data Source
  KAKENHI-PUBLICLY-21022027
[Presentation] Food-borne botulism and transepithelial transport of botulinum toxin2010
- Author(s)
  Yukako Fujinaga, Yo Sugawara, Takuhiro Matsumura, Yuki Takegahara
- Organizer
  第62回日本細胞生物学会(シンポジウム)シンポジウム3 病態の理解に向けた細胞内ロジスティクス研究
- Place of Presentation
  大阪(招待講演)
- Data Source
  KAKENHI-PUBLICLY-21022027
[Presentation] Reconstitution and dissection of epithelial barrier disrupting activity of type B botulinum HA.2010
- Author(s)
  竹ヶ原夕紀、菅原庸、松村拓大、藤永由佳子
- Organizer
  第83回日本細菌学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21390128
[Presentation] Botulinum hemagglutinin targets E-cadherin to disrupt the intercellular epithelial barrier.2010
- Author(s)
  Sugawara Y, Matsumura T, Takegahara T, Jin Y, Fujinaga Y.
- Organizer
  The Awaji International Forum on Infectionand Immunity
- Place of Presentation
  Awaji Island, Japan
- Data Source
  KAKENHI-PROJECT-21390128
[Presentation] Botulinum HA targets E-cadherin to disrupt the intercellular epithelial barrier.2010
- Author(s)
  Sugawara Y, Matsumura T, Fujinaga, Y.
- Organizer
  47^<th> IBRCC 2010, Intergency botulinum research coordinating committee meeting
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-21390128
[Presentation] Food-borne botulism and transepithelial transport of botulinum toxin2010
- Author(s)
  Yukako Fujinaga, Yo Sugawara, Takuhiro Matsumura, Yuki Takegahara
- Organizer
  第62回日本細胞生物学会(シンポジウム)シンポジウム3 病態の理解に向けた細胞内ロジスティクス研究
- Place of Presentation
  大阪(招待講演)
- Data Source
  KAKENHI-PROJECT-21390128
[Presentation] Development of human monoclonal antibodies against type A botulinum neurotoxin.2010
- Author(s)
  Matsumura T, Du A, Sugawara Y, Kohda T, Takahashi M, Kozaki S, Ikuta K, Fujinaga Y.
- Organizer
  47^<th> IBRCC 2010, Intergency botulinum research coordinating committee meeting
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-21390128
[Presentation] Botulinum HA targets E-cadherin to disrupt the intercellular epithelial barrier.2010
- Author(s)
  Sugawara Y, Matsumura T, Fujinaga, Y.
- Organizer
  47^<th> IBRCC 2010, Intergency botulinum research coordinating committee meeting
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PUBLICLY-21022027
[Presentation] ボツリヌス毒素複合体成分とE-cadherinの結合による上皮細胞間バリア破壊と毒素の腸管吸収2010
- Author(s)
  藤永由佳子、菅原庸、松村拓大
- Organizer
  第33回日本分子生物学会年回・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21390128
[Presentation] Mechanism for Epithelial Barrier Disruption by Botulinum HA2009
- Author(s)
  Takegahara, Y., Matsumura, T., Sugawara, Y., Fujinaga, Y.
- Organizer
  Etox 14 (European Workshop on Bacterial Protein Toxins)
- Place of Presentation
  Obemai, France
- Data Source
  KAKENHI-PUBLICLY-21022027
[Presentation] Mechanism for Epithelial Barrier Disruption by Botulinum HA2009
- Author(s)
  Takegahara, Y., Matsumura, T., Sugawara, Y., Fujinaga, Y.
- Organizer
  Etox 14 (European Workshop on Bacterial Protein Toxins)
- Place of Presentation
  Obernai, France
- Data Source
  KAKENHI-PROJECT-21390128
[Presentation] 上皮細胞バリア破壊因子botulinum HAのサブユニット機能解析2009
- Author(s)
  竹ヶ原夕紀、菅原庸、松村拓大、藤永由佳子
- Organizer
  第82回日本生化学大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-21022027
[Presentation] Disruption of the Epithelial Barrier by Botulinum Hemagglutinin (HA) (招待講演)2009
- Author(s)
  Yukako Fujinaga
- Organizer
  Third Annual Botulinum Research Symposium
- Place of Presentation
  Dartmouth, USA
- Data Source
  KAKENHI-PROJECT-21390128
[Presentation] ボツリヌスHAは上皮細胞バレア破壊因子である2009
- Author(s)
  竹ヶ原夕紀、菅原庸、松村拓大、藤永由佳子
- Organizer
  第62回日本細菌学会関西支部会
- Place of Presentation
  大阪
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-21390128
[Presentation] 上皮細胞バリア破壊因子botulinum HAのサブユニット機能解析2009
- Author(s)
  竹ヶ原夕紀、菅原庸、松村拓大、藤永由佳子
- Organizer
  第82回日本生化学大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21390128
[Presentation] ボツリヌスHAは上皮細胞バリア破壊因子である2009
- Author(s)
  竹ヶ原夕紀、菅原庸、松村拓大、藤永由佳子
- Organizer
  第62回日本細菌学会関西支部会
- Place of Presentation
  大阪
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PUBLICLY-21022027
[Presentation] Structure and function of hemagglutinin from Clostridium botulinum.2009
- Author(s)
  Kitadokoro, K., Takegahara, Y., Karatani, H., Fujinaga, Y.
- Organizer
  The 9^<th> Awaji International Forum on Infection and Innmunity.
- Place of Presentation
  淡路島
- Data Source
  KAKENHI-PROJECT-21390128
[Presentation] Structure and function of hemagglutinin from Clostridium botulinum.2009
- Author(s)
  Kitadokoro, K., Takegahara, Y., Karatani, H., Fujinaga, Y.
- Organizer
  The 9^<th> Awaji International Forum on Infection and Immunity.
- Place of Presentation
  淡路島
- Data Source
  KAKENHI-PUBLICLY-21022027
[Presentation] Disruption of the Epithelial Barrier by Botulinum Hemagglutinin (HA)(招待講演)2009
- Author(s)
  Yukako Fujinaga
- Organizer
  Third Annual Botulinum Research Symposium
- Place of Presentation
  Dartmouth, USA
- Data Source
  KAKENHI-PUBLICLY-21022027
[Presentation] ボツリヌスHA複合体構成サブユニットの有する腸管上皮細胞間バリア破壊活性の解析2008
- Author(s)
  竹ケ原夕紀、金英姫、菅原庸、松村拓大、藤永由佳子
- Organizer
  第81回日本細菌学会総会
- Place of Presentation
  京都
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570178
[Presentation] A new function of botulinum toxin associated proteins: The HA component disrupts intestinal epithelial intercellular junctions to increse toxin absorption.2007
- Author(s)
  Y., Fujinaga
- Organizer
  2007 International RIMD-CVRDC Joint Symposium
- Place of Presentation
  Suita, Osaka, Japan
- Year and Date
  2007-08-18
- Data Source
  KAKENHI-PROJECT-18050020
[Presentation] Mechanism of intestinal absorption of botulinum toxin.2007
- Author(s)
  Y., Fujinaga
- Organizer
  The 2nd Thailand-Japan Joint Forum on Infectious Diseases,
- Place of Presentation
  Bangkok, Thailand
- Year and Date
  2007-10-08
- Data Source
  KAKENHI-PROJECT-18050020
[Presentation] ボツリヌス神経毒素複合体の腸管上皮バリア通過機構2007
- Author(s)
  松村拓大、金英姫、株本祐子、竹ケ原タ紀、菅原庸、小熊恵二、藤永由佳子
- Organizer
  第54回毒素シンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18050020
[Presentation] Mechanism of intestinal absorption of botulinum toxin.2007
- Author(s)
  Y. Fujinaga
- Organizer
  The 2nd Thailand-Japan Joint Forum on Infectious Diseases,
- Place of Presentation
  Bangkok, Thailand
- Year and Date
  2007-10-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570178
[Presentation] ボツリヌスHA複合体による腸管上皮細胞間バリア破壊機構の解析2007
- Author(s)
  竹ケ原夕紀、金英姫、松村拓大、菅原庸、藤永由佳子
- Organizer
  第60回日本細菌学会関西支部会
- Place of Presentation
  大阪
- Year and Date
  2007-11-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570178
[Presentation] Transepithelial transport of the botulinum toxin via trans cellular and paracellular routes2007
- Author(s)
  Fujinaga, Y., Matsumura, T., Jin, Y., Takegahara, Y., Sugawara, Y
- Organizer
  IntemationalSymposium "Membranetraffic"Awaji-shima
- Place of Presentation
  Hyogo,Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570178
[Presentation] ボツリヌス神経毒素複合体に含まれる無毒成分(HA)は腸管上皮細胞バケア機能を破壊する2007
- Author(s)
  松村拓大、金英姫、株本祐子、竹ケ原タ紀、菅原庸、小態惠二、藤永由佳子
- Organizer
  第30回日本分子生物学会年回・第日本生化学会大会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18050020
[Presentation] Mechanism of intestinal absorption of botulinum toxin2007
- Author(s)
  Fujinaga, Y
- Organizer
  The 2nd Thailand-Japan Joint Forum on Infectious Diseases (Invited speaker)
- Place of Presentation
  Bangkok, Thailand
- Year and Date
  2007-10-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570178
[Presentation] ボツリヌス神経毒素複合体の腸管からの吸収機構について2007
- Author(s)
  藤永由佳子、松村拓大、金英姫、竹ケ原夕紀、株本祐子、小熊惠二
- Organizer
  第80回日本細菌学会総会
- Place of Presentation
  大阪
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570178
[Presentation] ボツリヌス神経毒素複合体の腸管上皮細胞バリア通過機構について2007
- Author(s)
  松村拓大、金英姫、竹ケ原夕紀、株本祐子、小熊惠二、藤永由佳子
- Organizer
  文部科学省特定領域研究感染マトリックス第5回感染症沖縄フォーラム
- Place of Presentation
  沖縄
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570178
[Presentation] Disruption of the intestinal paracellular barrier by botulinum toxin complex.2007
- Author(s)
  T., Matsumura・Y., Jin・Y., Kabumoto・Y., Takegahara・Y., Sugawara・K., Oguma・W.i., Lencer・Y., Fujinaga
- Organizer
  The 7th Awaji International Forum on Infection and Immunity
- Place of Presentation
  Hoyogo, Japan
- Data Source
  KAKENHI-PROJECT-18050020
[Presentation] A new function of botulinum toxin associated proteins : The HA component disrupts intestinal epithelial intercellular junctions to increase toxin absorption2007
- Author(s)
  Fujinaga, Y
- Organizer
  International RIMD-CVRDC Joint Symposium Suita
- Place of Presentation
  Osaka, Japan
- Year and Date
  2007-12-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570178
[Presentation] Disruption of the intestinal paracellular barrier by botulinum toxin complex2007
- Author(s)
  Matsumura, T., Jin, Y., Kabumoto, Y., Takegahara, Y., Sugawara, Y., Oguma, K., Lencer, WI., Fujinaga, Y
- Organizer
  The 7th Awaji International Forum on Infection and Immunity
- Place of Presentation
  Hyogo, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570178
[Presentation] Mechanism of intestinal absorption of botulinum toxin.2007
- Author(s)
  Y.fujinaga
- Organizer
  The 2nd Thailand-Japan Joint Forum on In fectious Diseases,
- Place of Presentation
  Bangkok, Thailand
- Year and Date
  2007-10-08
- Data Source
  KAKENHI-PROJECT-18570178
[Presentation] ボツリヌス神経毒素複合体に含まれる無毒成分(HA)は腸管上皮細胞バリア機能を破壊する2007
- Author(s)
  松村拓大、金英姫、株本祐子、竹ケ原夕紀、菅原庸、小熊惠二、藤永由佳子
- Organizer
  第30回日本分子生物学会年回・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570178
[Presentation] Transepithelial transport of the botulinum toxin via trans cellular and paracellular routes2007
- Author(s)
  Y. Fujinaga, et. al.
- Organizer
  International Symposium "Membrane traffic"
- Place of Presentation
  Awaji-shima Hyogo, Japan.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570178
[Presentation] ボツリヌス神経毒素複合体の腸管上皮バリア通過機構2007
- Author(s)
  松村拓大、金英姫、株本祐子、竹ケ原夕紀、菅原庸、小熊惠二、藤永由佳子
- Organizer
  第54回毒素シンポジウム
- Place of Presentation
  大阪
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570178
[Presentation] Disruption of the intestinal paracellular barrier by botulinum toxin complex.2007
- Author(s)
  T. Matsumura, Y. Jin, Y. Kabumoto, Y. Takegahara, Y Sugawara, K. Oguma, W. I. Lencer, and Y. Fujinaga
- Organizer
  The 7th Awaji International Forum on Infection and Immunity
- Place of Presentation
  Hyogo, Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570178
[Presentation] ボツリヌス神経毒素複合体の腸管上皮細胞バリア通過機構2007
- Author(s)
  藤永由佳子、松村拓大、金英姫、竹ケ原夕紀、株本祐子、小熊惠二
- Organizer
  感染マトリックス応用ゲノムジョイントミーティング第1回細菌学・若手コロッセウム
- Place of Presentation
  神戸
- Year and Date
  2007-01-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570178
[Presentation] A new function of botulinum toxin associated proteins: The HA component disrupts intestinal epithelial intercellular junctions to increase toxin absorption.2007
- Author(s)
  Y. Fujinaga
- Organizer
  2007 International RIMD-CVRDC Joint Symposium
- Place of Presentation
  Suita, Osaka, Japan
- Year and Date
  2007-12-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570178
[Presentation] ボツリヌスHA複合体による腸管上皮細胞間バリア破壊機構の解析2007
- Author(s)
  竹ケ原タ紀、金英姫、松村拓大、菅原庸、藤永由佳子
- Organizer
  第60回日本細菌学会関西支部会
- Place of Presentation
  大阪
- Year and Date
  2007-11-10
- Data Source
  KAKENHI-PROJECT-18050020
[Presentation] ボツリヌス神経毒素複合体の腸管上皮細胞バリア通過機構の解析2006
- Author(s)
  藤永由佳子、松村拓大、金英姫、竹ケ原夕紀、株本祐子
- Organizer
  文部科学省特定領域研究メンブレントラフィック〜分子機構から高次機能への展開〜第4回班会議
- Place of Presentation
  香川県小豆島
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570178

1. OGUMA Keiji (00002262)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. INOUE Kaoru (40260103)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. 松村拓大 (00456930)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 小林伸英 (30712799)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TOMOCHIKA Kenichi (00093691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NISHIKAWA Jun (30218127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YOKOTA Kenji (00243460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. IIDA Noriho (40705604)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 平井義一 (00127581)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 北所健悟 (60283587)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 公文裕巳 (30144760)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 油谷雅広 (20648810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 北村和哉 (00579633)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. LYNN Hughes

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Fujinaga Yukako 藤永 由佳子

藤永 由佳子 フジナガ ユカコ

FUJINAGA Yukako 藤永 由佳子

Research Projects

Research Products

Co-Researchers

共生細菌による病原性クロストリジウム属菌の腸管感染制御とその機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

In vivo analysis of gut microbiota which prevents the intestinal botulismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of genes of unknouwn function exist in the toxin gene related region of C. botulinumPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Roles of Enterococcus in carcinogenesis and inflammation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ボツリヌスHAの細胞間バリア破壊作用の分子機構と病態における意義についてPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ボツリヌスHAと腸管上皮細胞の相互作用の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ボツリヌス神経毒素複合体の宿主腸管上皮細胞バリア通過機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research on the mechanism of tight jundan regulafion by using botulinum toxir complexPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Search for Clostridium botulinum derived Substance that has a function to disrupt the intestinal epithelial barrier.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of tertial structure and function of non-toxic components associating with Clostridium botulinum neurotoxins.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of absorption of Clostridium botulinum toxins from the small infestine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of absorption of Clostridium botulinum neurotoxin-nontoxic component complex from the small intestine.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

牛のボツリヌスC型、D型中毒の両方に効果のあるリコンビナントワクチンの作製Principal Investigator

Principal Investigator

Fujinaga Yukako 藤永由佳子

藤永由佳子フジナガユカコ

FUJINAGA Yukako 藤永由佳子

[Book] 第29回阿蘇シンポジウム記録感染防御のBird's-eye view[ボツリヌス毒素複合体と宿主腸管上皮細胞]2006