• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

IEIRI Ichiro  家入 一郎

ORCIDConnect your ORCID iD *help
Researcher Number 60253473
Other IDs
External Links
Affiliation (Current) 2022: 九州大学, 大学病院, 大学院担当教授
Affiliation (based on the past Project Information) *help 2020 – 2022: 九州大学, 大学病院, 大学院担当教授
2019: 九州大学, 九州大学病院, 教授
2015 – 2018: 九州大学, 薬学研究院, 教授
2011 – 2016: 九州大学, 薬学研究科(研究院), 教授
2012: 九州大学, 薬学研究院, 教授 … More
2009 – 2011: Kyushu University, 大学院・薬学研究院, 教授
2008 – 2009: 九州大学, 大学院・薬学研究科, 准教授
2007 – 2009: Kyushu University, 大学院・薬学研究院, 准教授
2007: Kyushu University, Graduate School of Pharmaceutical Sciences, Associate Professor
2006: 九州大学, 大学院薬学研究院, 助教授
2005: 九州大学, 大学院・薬学研究院, 助教授
2002 – 2003: 鳥取大学, 医学部附属病院, 助教授
2001: 鳥取大学, 医学部・附属病院, 助教授
2001: 鳥取大学, 医学部・附属病院薬剤部, 助教授
2000: 鳥取大学, 医学部・附属病院, 薬剤部・助教授
1999: 鳥取大学, 医学部・附属病院薬剤部, 副薬剤部長
1998: 九大, 助手 Less
Review Section/Research Field
Principal Investigator
Medical pharmacy / 応用薬理学・医療系薬学 / Applied pharmacology / Medium-sized Section 47:Pharmaceutical sciences and related fields / Gastroenterology / Basic Section 47060:Clinical pharmacy-related
Except Principal Investigator
Medical pharmacy / 応用薬理学・医療系薬学 / Biological Sciences
Keywords
Principal Investigator
CYP3A4 / 薬剤反応性 / miRNA / 臨床試験 / MDR1 / SNPs / 遺伝子 / 遺伝子多型 / 個人差解明 / メチル化 … More / コヒーシンモデル / DNAメチル化 / バイオマーカー / BCRP / CYP3A5 / 薬物トランスポーター / インプリンティング制御 / アレル発現パターン / インプリント / 薬物動態 / コピー数多型 / CNV / PK / PD遺伝子 / 肺癌 / メトトレキセート / DHFR / 血球中内活性 / MTX / グルタミン付加体 / トランスポーター遺伝子 / 発現制御 / 遺伝子空間的転写モデル / 立体空間的発現制御 / CpGアイランド / オーダーメード医療 / DMR / コヒーシン / microRNA / P-gp / p-糖タンパク質 / 転写制御 / 抗がん剤 / 耐性克服 / ゲノム / 薬剤応答性 / 活性評価 / ABCトランスポーター / p-糖タンパク / 基礎研究 / 4MU / 胎盤 / hapolotype / diplotype / タクロリムス / 部分肝移植 / 中枢毒性 / MDR1遺伝子 / MRPs遺伝子 / 薬物脳移行 / モルヒネ / ジゴキシン / オーダーメイド医療 / ABC transporters / P-glycoprotein / Basic research / Clinical Study / アレル不均等発現 / エピジェネティックス / ヒストンアセチル化 / ミダゾラム / イトラコノナゾール / allelic expression imbalance / epigenetics / midazolam / itraconazole / clinical study / 生体試料中濃度 / トランスポーター / 薬物代謝酵素 / 個別化医療 / メタボローム解析 / 臨床応用 / RNAメチル化 / エピトランスクリプトーム解析 / 生活習慣病 / 高血糖 / 発現変動機構 / 臓器特異的 / 体内動態変動 / 薬効動態変動 / TDM / 治療薬物モニタリング / 血漿中miRNA / 個別化 / 精度向上 … More
Except Principal Investigator
MDR1 / MRP2 / 遺伝子多型 / 発現制御 / トランスポーター / 薬剤反応性 / 生理学的薬物速度論モデル / 薬物トランスポーター / ABCトランスポーター / MRP1 / cMOAT / 遺伝的多型 / chronopharmacology / antitumor effect / cisplatin / mdr1 / mrp2 / bcrp / adriamycin / コピーナンバー多型 / miRNA / インプリンティング / CYP3A4 / SNPs / エピジェネティックス / ゲノム / 薬物動態 / テルミサルタン / UGT / オルメサルタン / プラバスタチン / 薬物代謝酵素 / 薬物間相互作用 / モデリング&シミュレーション / PET/SPECTプローブ / 創薬支援システム / 個人間変動 / バーチャルクリニカルスタディ / フェノタイピング / バイオマーカー / クルクミン Less
  • Research Projects

    (21 results)
  • Research Products

    (52 results)
  • Co-Researchers

    (16 People)
  •  体液中臓器特異的miRNAに注目した病態時における体内・薬効動態変動の機序解明Principal Investigator

    • Principal Investigator
      家入 一郎
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Kyushu University
  •  血漿中miRNA情報を付加した治療薬物モニタリングの個別化精度向上を目指す新展開Principal Investigator

    • Principal Investigator
      家入 一郎
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 47:Pharmaceutical sciences and related fields
    • Research Institution
      Kyushu University
  •  Mechanism of regulation of drug transporter expression in lifestyle-related diseases by epitranscriptomicsPrincipal Investigator

    • Principal Investigator
      Ieiri Ichiro
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 47:Pharmaceutical sciences and related fields
    • Research Institution
      Kyushu University
  •  Evaluation between CYP3A4 activity and DNA methylationPrincipal Investigator

    • Principal Investigator
      Ieiri Ichiro
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied pharmacology
    • Research Institution
      Kyushu University
  •  Analysis of miRNA as a novel biomarker for estimating transporter's function in the human organsPrincipal Investigator

    • Principal Investigator
      Ieiri Ichiro
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Medical pharmacy
    • Research Institution
      Kyushu University
  •  DNA methylation biomarkers for estimation of the activity of CYP3A4 in human liversPrincipal Investigator

    • Principal Investigator
      Ieiri Ichiro
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied pharmacology
    • Research Institution
      Kyushu University
  •  Identification of endogenous biomarkers to predict the altered activities of drug transporters by environmental factors

    • Principal Investigator
      Hirota Takeshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Kyushu University
  •  The role of miR-27a in regulation of P-gp expressionPrincipal Investigator

    • Principal Investigator
      IEIRI Ichiro
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Medical pharmacy
    • Research Institution
      Kyushu University
  •  Development of quantitative prediction methods for alteration in pharmacokinetics caused by interindividual variability in transporter function and transporter-mediated drug-drug interaction

    • Principal Investigator
      Sugiyama Yuichi
    • Project Period (FY)
      2012 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Medical pharmacy
    • Research Institution
      Institute of Physical and Chemical Research
  •  Analysis of cohesin model in CYP3A4 gene and individual phenotypic statusPrincipal Investigator

    • Principal Investigator
      IEIRI ICHIRO
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      Kyushu University
  •  Cohesin-dependentregulation of the expression of drug transporter genesPrincipal Investigator

    • Principal Investigator
      IEIRI Ichiro
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Medical pharmacy
    • Research Institution
      Kyushu University
  •  薬物動態・薬効の変動に関与する薬物トランスポーターの遺伝子多型の包括的実証研究

    • Principal Investigator
      Sugiyama Yuichi
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Investigation of clinical impacts of CNV in the pharmacokinetic-related genesPrincipal Investigator

    • Principal Investigator
      IEIRI Ichiro
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      Kyushu University
  •  薬物トランスポーター遺伝子情報を駆使したリウマチ治療薬の個別適正化使用Principal Investigator

    • Principal Investigator
      家入 一郎
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Medical pharmacy
    • Research Institution
      Kyushu University
  •  Alternative mechanisms of gene regulation for pharmacokinetics related genes

    • Principal Investigator
      HIGUCHI Shun
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      Kyushu University
  •  抗腫瘍効果に及ぼす腫瘍組織中トランスポーター発現の日周リズム

    • Principal Investigator
      樋口 駿
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Medical pharmacy
    • Research Institution
      Kyushu University
  •  The role of allelic expression imbalance (AER) in interindividual differences in CYP3A4 activity and it's clinical implications.Principal Investigator

    • Principal Investigator
      IEIRI Ichiro
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      Kyushu University
  •  ゲノムインプリンティング制御によるCYP3A4発現・機能の個人間変動解析Principal Investigator

    • Principal Investigator
      家入 一郎
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Tottori University
  •  In vivo functional characterization of the ABC transporters based on the genetic polymorphismsPrincipal Investigator

    • Principal Investigator
      IEIRI Ichiro
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Tottori University
  •  ABCトランスポーター遺伝子の多型解析と臨床意義の解明

    • Principal Investigator
      HIGUCHI Shun
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Kyushu University
  •  チトクロームP4502C9の全遺伝子解析と表現型との関連解明Principal Investigator

    • Principal Investigator
      家入 一郎
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyushu University

All 2020 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book Patent

  • [Book] 分子薬物動態学2008

    • Author(s)
      家入 一郎(分担)
    • Total Pages
      690
    • Publisher
      南山堂
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390043
  • [Book] 最新創薬学2007、遺伝子医学MOOK No.72007

    • Author(s)
      家入 一郎(分担)
    • Total Pages
      303
    • Publisher
      メデイカルドゥ社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390043
  • [Journal Article] Small-dosing clinical study: Pharmacokine- tic, pharmacogeno- mics (SLCO2B1 and ABCG2), and interaction (atorvastatin and grapefruit juice) profiles of 5 probes for OATP2B1 and BCRP.2017

    • Author(s)
      Kashihara Y, Ieiri I, Yoshikado T, Maeda K, Fukae M, Kimura M, Hirota T, Matsuki S, Irie S, Izumi N, Kusuhara H, Sugiyama Y.
    • Journal Title

      J Pharm Sci

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24229002
  • [Journal Article] Effect of Curcumin on Sulfasalazine Pharmacokinetics in Healthy Volunteers2016

    • Author(s)
      Tomoko Tokumoto, Takeshi Hirota, Keisuke Gotanda, Miyuki Kimura, Shin Irie, Masato Fukae and Ichiro Ieiri
    • Journal Title

      Journal of Drug Metabolism & Toxicology

      Volume: 7 Pages: 1000206-1000206

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460199
  • [Journal Article] Circulating intestine-derived exosomal miR-328 in plasma, a possible biomarker for estimating BCRP function in the human intestines2016

    • Author(s)
      Gotanda K, Hirota T, Saito J, Fukae M, Egashira Y, Izumi N, Deguchi M, Kimura M, Matsuki S, Irie S, Ieiri I
    • Journal Title

      Scientific Reports

      Volume: 6 Pages: 32299-32299

    • DOI

      10.1038/srep32299

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460199, KAKENHI-PROJECT-15K15004
  • [Journal Article] Clarification of the Mechanism of Clopidogrel- Mediated Drug-Drug Interaction in a Clinical Cassette Small-dose Study and Its Prediction Based on In Vitro Information.2016

    • Author(s)
      Kim SJ, Yoshikado T, Ieiri I, Maeda K, Kimura M, Irie S, Kusuhara H, Sugiyama Y.
    • Journal Title

      Drug Metab Dispos

      Volume: 44 Pages: 1622-1632

    • DOI

      10.1124/dmd.116.070276

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24229002
  • [Journal Article] Sulfasalazine disposition in subject with 376C>T (nonsense mutation) and 421C>A variants in ABCG2 gene.2015

    • Author(s)
      Gotanda K, Tokumoto T, Hirota T, Fukae M, Ieiri I.
    • Journal Title

      British Journal of Clinical Pharmacology

      Volume: 未定 Pages: 1236-1237

    • DOI

      10.1111/bcp.12654

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460199, KAKENHI-PROJECT-15J00726
  • [Journal Article] Direct and rapid genotyping of SLCO1B1 388A>G and 521T>C in human blood specimens using the SmartAmp-2 method.2013

    • Author(s)
      Yoshida K, Takano J, Ishizu Y, Lezhava A, Ieiri I, Maeda K, Hayashizaki Y and Sugiyama Y.
    • Journal Title

      AAPS J

      Volume: 15 Pages: 618-622

    • DOI

      10.1208/s12248-013-9471-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24229002
  • [Journal Article] Mechanisms of pharmacokinetic enhancement between ritonavir and saquinavir; micro/small dosing tests using midazolam (CYP3A4), fexofenadine (p-glycoprotein), and pravastatin (OATP1B1) as probe drugs.2013

    • Author(s)
      Ieiri I, Tsunemitsu S, Maeda K, Ando Y, Izumi N, Kimura M, Yamane N, Okuzono T, Morishita M, Kotani N, Kanda E, Deguchi M, Matsuguma K, Matsuki S, Hirota T, Irie S, Kusuhara H, Sugiyama Y.
    • Journal Title

      J Clin Pharmacol

      Volume: 53 Pages: 1-16

    • DOI

      10.1002/jcph.62

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24229002, KAKENHI-PROJECT-24689009
  • [Journal Article] Association study of genetic polymorphisms of drug transporters, SLCO1B1, SLCO1B3 and ABCC2, in African-Americans, Hispanics and Caucasians and olmesartan exposure.2012

    • Author(s)
      Endo S, Fukahori A, Tokuhiro S, Shinagawa A, Walker J, Yoshihara K, Ishizuka H, Ieiri I, Sugiyama Y.
    • Journal Title

      J Hum Genet

      Volume: 57 Pages: 531-44

    • DOI

      10.1038/jhg.2012.63

    • NAID

      10031056697

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24229002
  • [Journal Article] Association of multidrug resistance-associated protein 2 single nucleotide polymorphism rs12762549 with the basal plasma levels of phase II metabolites of isoflavonoids in healthy Japanese individuals.2012

    • Author(s)
      Kato K, et al
    • Journal Title

      Pharmacogenet Genomics

      Volume: 22 Pages: 344-354

    • DOI

      10.1097/fpc.0b013e3283517012

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23136101, KAKENHI-PROJECT-24229002
  • [Journal Article] Microdosing clinical study: pharmacokinetic, pharmacogenomic (SLCO2B1), and interaction (grapefruit Juice) profiles of celiprolol following the oral microdose and therapeutic dose.2012

    • Author(s)
      Ieiri I, Doi Y, Maeda K, Sasaki T, Kimura M, Hirota T, Chiyoda T, Miyagawa M, Irie S, Iwasaki K, Sugiyama Y.
    • Journal Title

      J Clin Pharmacol

      Volume: 52 Pages: 1078-89

    • DOI

      10.1177/0091270011408612

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24229002
  • [Journal Article] Pharmacokinetic interaction study of sulfasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP.2012

    • Author(s)
      Kusuhara H, et al
    • Journal Title

      British Journal of Pharmacology

      Volume: (In press) Pages: 1793-1803

    • DOI

      10.1111/j.1476-5381.2012.01887.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23136101, KAKENHI-PROJECT-23590206, KAKENHI-PROJECT-24229002
  • [Journal Article] Pharmacogenomic/pharmacokinetic assessment of a four-probe cocktail for CYPs and OATPs following oral microdosing.2012

    • Author(s)
      Ieiri I, Fukae M, Maeda K, Ando Y, Kimura M, Hirota T, Nakamura T, Iwasaki K, Matsuki S, Matsuguma K, Kanda E, Deguchi M, Irie S, Sugiyama Y.
    • Journal Title

      Int J Clin Pharmacol Ther

      Volume: 50 Pages: 689-700

    • DOI

      10.5414/cp201763

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24229002
  • [Journal Article] Interindividual differences in placental expression of the SLC22A2 (OCT2) gene: relationship to epigenetic variations in the 5'-upstream regulatory region2011

    • Author(s)
      Saito J, Hirota T, Kikunaga N, Otsubo K, Ieiri I
    • Journal Title

      Journal of pharmaceutical sciences

      Volume: 100(9) Pages: 3875-83

    • DOI

      10.1002/jps.22595

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659083
  • [Journal Article] Systematic screening of human ABCC3 polymorphisms and their effects on MRP3 expression and function.2011

    • Author(s)
      Sasaki T, Hirota T, Ryokai Y, Kobayashi D, Kimura M, Irie S, Higuchi S, Ieiri I.
    • Journal Title

      Drug Metab Pharmacokinet. Apr22

    • NAID

      130004463197

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390048
  • [Journal Article] Novel large-scale deletion (whole exon 7) in the ABCC2 gene in a patient with the Dubin-Johnson syndrome.2009

    • Author(s)
      Kanda D, Takagi H, Kawahara Y, Yata Y, Takakusagi T, Hatanaka T, Yoshinaga T, Iesaki K, Kashiwabara K, Higuchi T, Mori M, Hirota T, Higuchi S, Ieiri I.
    • Journal Title

      Drug Metab Pharmacokinet. 24(5)

      Pages: 464-468

    • NAID

      130004463097

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390048
  • [Journal Article] Quantitative population pharmacokinetic analysis of pravastatin using an enterohepatic circulation model combined with pharmacogenomic Information on SLCO1B1 and ABCC2 polymorphisms2009

    • Author(s)
      Ide, T., Sasaki, T., Maeda, K., Higuchi, S., Sugiyama, Y., Ieiri, I.
    • Journal Title

      J Clin Pharmacol 49

      Pages: 1309-1317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20018006
  • [Journal Article] Epigenetic regulation of genes encoding drug-metabolizing enzylnes and transporters;DNA methylation and other mechanisms2008

    • Author(s)
      Hirota T, Takane H, Higuchi S, Ieiri I
    • Journal Title

      Curr Drug Metab 9

      Pages: 34-38

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390043
  • [Journal Article] Pharmacokinetic interaction between pravastatin and olmesartan in relation to SLCO1B1 polymorphism2008

    • Author(s)
      Suwannakul S, Ieiri I, Kimura M, Kawabata K, Kusuhara H, Hirota T, Irie S, Sugiyama Y, Higuchi S
    • Journal Title

      J Hum Genet 53

      Pages: 899-904

    • NAID

      10022603002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20018006
  • [Journal Article] Pharmacogenetic determenants of variability in liped-lowering response to pravastat in therapy2006

    • Author(s)
      Takane H, Miyata M, Burioka N, Shioemasa C, Shimizu E, Otsubo K, Ieiri I
    • Journal Title

      J Hum Genet 51

      Pages: 822-826

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390043
  • [Journal Article] CYP3A4遺伝子発現調節と循環器薬物治療2006

    • Author(s)
      家入 一郎
    • Journal Title

      心電図、26巻、3号、223-8頁、2006年 26

      Pages: 223-228

    • NAID

      10019172000

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390043
  • [Journal Article] Expression mechanisms of human CYP3A4 gene2006

    • Author(s)
      Ieiri, I
    • Journal Title

      Jpn J Cardiology 26

      Pages: 223-228

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390043
  • [Journal Article] CYP3A4遺伝子発現調節と循環器薬物治療2006

    • Author(s)
      家入一郎
    • Journal Title

      Jpn J Electrocardiology 26

      Pages: 223-228

    • NAID

      10019172000

    • Data Source
      KAKENHI-PROJECT-17390043
  • [Journal Article] Rifampin reduces the analgesic effect of transdermal fentanyl.2005

    • Author(s)
      Ieiri I et al.
    • Journal Title

      The annals of Pharmacotherapy 39

      Pages: 2139-2140

    • Data Source
      KAKENHI-PROJECT-17390043
  • [Patent] DNAメチル化解析方法ならびにCYP3A4発現量推定方法2018

    • Inventor(s)
      家入一郎、廣田 豪
    • Industrial Property Rights Holder
      国立大学法人九州大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Acquisition Date
      2019
    • Data Source
      KAKENHI-PROJECT-17H04103
  • [Patent] DNAメチル化解析方法ならびにCYP3A4発現量推定方法2015

    • Inventor(s)
      家入一郎
    • Industrial Property Rights Holder
      家入一郎
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-02-24
    • Overseas
    • Data Source
      KAKENHI-PROJECT-26293121
  • [Patent] DNAメチル化解析方法ならびにCYP3A4発現量推定方法2014

    • Inventor(s)
      家入一郎
    • Industrial Property Rights Holder
      家入一郎
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-06-01
    • Data Source
      KAKENHI-PROJECT-26293121
  • [Presentation] RNAメチル化解析による糖尿病発症時のトランスポーター発現変動メカニズムの解明2020

    • Author(s)
      香川竜希, 清田将裕, 小野未央里, 廣田豪, 家入一郎
    • Organizer
      第41回日本臨床薬理学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K22502
  • [Presentation] Small-dosing clinical study: pharmacoki- netic, pharmacogeno-mic (SLCO2B1 and ABCG2), and interaction (atorvastatin and grapefruit Juice) profiles of five probes for OATP2B1 and BCRP.2017

    • Author(s)
      Kashihara Y, Ieiri I, Yoshikado T, Maeda K, Fukae M, Kimura M, Hirota T, Matsuki S, Irie S, Izumi N, Kusuhara H, Sugiyama Y.
    • Organizer
      15th International Congress of Therapeutic Drug Monitoring & Clinical Toxicology
    • Place of Presentation
      国立京都国際会館 (京都府京都市)
    • Year and Date
      2017-09-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24229002
  • [Presentation] クロピドグレルの関与する薬物間相互作用のカセットドーズ臨床試験に基づいたメカニズム解析とin vitro試験に基づいた予測.2016

    • Author(s)
      Soo-Jin Kim, 吉門 崇, 家入 一郎, 前田 和哉, 木村 美由紀, 入江 伸, 楠原 洋之, 杉山 雄一.
    • Organizer
      日本薬剤学会第31年会
    • Place of Presentation
      長良川国際会議場(岐阜県岐阜市)
    • Year and Date
      2016-05-20
    • Data Source
      KAKENHI-PROJECT-24229002
  • [Presentation] ABCG2遺伝子376C>T変異がスルファサラジンの体内動態に与える影響2016

    • Author(s)
      廣田豪、五反田圭介、徳本知子、深江真登、家入一郎
    • Organizer
      日本薬物動態学会 第31回年会
    • Place of Presentation
      長野県松本市
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-15K15004
  • [Presentation] Clopidogrel-mediated drug-drug interaction on CYP2C8 and OATP1B1: in vitro inhibitory effect and in vivo clinical study.2016

    • Author(s)
      Kim S.J, Yoshikado T, Ieiri I, Maeda K, Kimura M, Irie S, Kusuhara H, Sugiyama Y.
    • Organizer
      日本薬物動態学会第31回年会
    • Place of Presentation
      キッセイ文化ホール(長野県松本市)
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-24229002
  • [Presentation] Sulfasalazine disposition in subject with 376C>T (nonsense mutation) variant in ABCG2 gene2016

    • Author(s)
      Takeshi Hirota, Keisuke Gotanda, Tomoko Tokumoto, Masato Fukae and Ichiro Ieiri
    • Organizer
      International Society for the Study of Xenobiotics
    • Place of Presentation
      Busan, Korea
    • Year and Date
      2016-06-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460199
  • [Presentation] ABCG2遺伝子376C>T変異がスルファサラジンの体内動態に与える影響2016

    • Author(s)
      廣田豪、五反田圭介、徳本知子、深江真登、家入一郎
    • Organizer
      日本薬物動態学会 第31回年会
    • Place of Presentation
      長野県松本市
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-26460199
  • [Presentation] miR-27a 374aによるP-gpの発現制御機構の解明2015

    • Author(s)
      水永 茉梨, 廣田 豪, 安井 俊貴, 山口 晃平, 家入 一郎
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-26
    • Data Source
      KAKENHI-PROJECT-25670078
  • [Presentation] Clarification of the mechanism of clopidogrel-mediated drug-drug interaction on the pharmacokinetics of repaglinide in a clinical cassette small-dose study.2015

    • Author(s)
      Kim S.J, Yoshikado T, Ieiri I, Maeda K, Kimura M, Irie S, Kusuhara H, Sugiyama Y.
    • Organizer
      日本薬物動態学会第30回年会
    • Place of Presentation
      タワーホール船堀(東京都江戸川区)
    • Year and Date
      2015-11-12
    • Data Source
      KAKENHI-PROJECT-24229002
  • [Presentation] クルクミンが消化管BCRP発現へ与える影響評価2015

    • Author(s)
      徳本 知子, 廣田 豪, 五反田 圭介, 深江 真登, 家入 一郎
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-26
    • Data Source
      KAKENHI-PROJECT-26460199
  • [Presentation] 遺伝子情報に基づいた個別化医療の展開 -現状と展望-2014

    • Author(s)
      家入 一郎
    • Organizer
      日本医療薬学会第53回公開シンポジウム
    • Place of Presentation
      長崎県長崎市、長崎大学医学部講堂
    • Year and Date
      2014-07-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-24229002
  • [Presentation] ヒトCYP3A4 遺伝子発現のゲノム空間構造解析に基づく個人差解明2013

    • Author(s)
      江口 駿介, 廣田 豪, 舞 彩華, 家入一郎
    • Organizer
      日本薬学会 第133年会
    • Year and Date
      2013-03-28
    • Data Source
      KAKENHI-PROJECT-23390035
  • [Presentation] エピジェネティック制御機構に基づくCYP3A4遺伝子発現制御メカニズムの解析2013

    • Author(s)
      藤田 麻里絵、江口 駿介、廣田 豪、家入 一郎
    • Organizer
      第30回日本薬学会九州支部大会
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-23390035
  • [Presentation] エピジェネティック制御機構に基づくCYP3A4 遺伝子発現制御メカニズムの解析2013

    • Author(s)
      藤田 麻里絵, 江口 駿介, 廣田 豪, 家入 一郎
    • Organizer
      第30回日本薬学会九州支部大会
    • Year and Date
      2013-12-08
    • Data Source
      KAKENHI-PROJECT-23390035
  • [Presentation] ヒトCYP3A4遺伝子発現のゲノム空間構造解析に基づく個人差解明2013

    • Author(s)
      江口駿介、廣田豪、舞彩華、家入一郎
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-28
    • Data Source
      KAKENHI-PROJECT-23659083
  • [Presentation] CYP3A4 遺伝子発現の個人差解明を指向したエピジェネティック解析2011

    • Author(s)
      江口 駿介, 廣田 豪, 家入 一郎
    • Organizer
      第28回日本薬学会九州支部大会
    • Year and Date
      2011-12-10
    • Data Source
      KAKENHI-PROJECT-23390035
  • [Presentation] Pharmacogenomics of Drug Transporters in Humans.2010

    • Author(s)
      Ieiri Ichiro
    • Organizer
      18^<th> International Symposium on Microsomes and Drug Oxidations
    • Place of Presentation
      Beijing (China)
    • Year and Date
      2010-05-19
    • Data Source
      KAKENHI-PROJECT-20390048
  • [Presentation] 薬物動態関連遺伝子のCopy Number Variation解析とその活用における留意点日本薬学会2009

    • Author(s)
      家入一郎、木下智広、廣田豪、安東幸恵、樋口駿
    • Organizer
      第129回年会
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2009-03-28
    • Data Source
      KAKENHI-PROJECT-20390048
  • [Presentation] Determination of CYP2D6 copy number variation by real-time quantitative PCR in Japanese.2008

    • Author(s)
      安東幸恵, 木下智広, 廣田豪, 樋口駿, 家入一郎
    • Organizer
      2^<nd> Asian Pacific ISSX Regional Meeting
    • Place of Presentation
      School of pharmacy, Fudan University
    • Year and Date
      2008-05-13
    • Data Source
      KAKENHI-PROJECT-20390048
  • [Presentation] Real Time PCR法を用いた薬物動態関連遺伝子のCopy Number Variation (CNV)解析2008

    • Author(s)
      木下智広、廣田豪、安東幸恵、家入一郎、樋口駿
    • Organizer
      第25回日本薬学会九州支部大会
    • Place of Presentation
      九州保健福祉大学薬学部
    • Year and Date
      2008-12-07
    • Data Source
      KAKENHI-PROJECT-20390048
  • [Presentation] CYP3A4遺伝子近傍領域のエピジェネティック解析2007

    • Author(s)
      大石 佳奈、家入 一郎
    • Organizer
      日本薬学会医療薬学部会
    • Place of Presentation
      東京
    • Year and Date
      2007-12-16
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390043
  • [Presentation] ヒトCYP3A4遺伝子発現のゲノム空間構造解析に基づく個人差解明

    • Author(s)
      家入 一郎
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23390035
  • [Presentation] ヒトCYP3A4遺伝子発現のゲノム空間構造解析に基づく個人差解明

    • Author(s)
      家入一郎
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23659083
  • [Presentation] 薬物トランスポーターの臓器別・包括的な機能の理解と臨床への活用

    • Author(s)
      家入 一郎
    • Organizer
      第35回日本臨床薬理学会総会
    • Place of Presentation
      愛媛県松山市、ひめぎんホール
    • Year and Date
      2014-12-04 – 2014-12-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-24229002
  • 1.  HIROTA Takeshi (80423573)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 20 results
  • 2.  HIGUCHI Shun (40218699)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  OTSUBO Kenji (80260701)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 4.  NANBA Eiji (40237631)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  Sugiyama Yuichi (80090471)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 15 results
  • 6.  前田 和哉 (00345258)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 13 results
  • 7.  BURIOKA Naoto (50252854)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  藤 秀人 (90346809)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  楠原 洋之 (00302612)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 10.  渡邊 恭良 (40144399)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  吉門 崇 (70535096)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 12.  新垣 友隆 (60643187)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  伊藤 澄人 (20728969)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  田畑 香織 (90464388)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  URAE Akinori
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  藤田 卓也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to connect your ORCID iD to this researcher?
* This action can be performed only by the researcher themselves.

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi