Nishio Kenji 西尾健治

… Alternative Names

西尾健治ニシオケンジ

NISHIO Kenji 西尾健治

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Researcher Number	60254489
Other IDs
External Links
Affiliation (Current)	2025: 奈良県立医科大学, 医学部, 医員
Affiliation (based on the past Project Information) *help	2023: 奈良県立医科大学, 医学部, 医員 2014 – 2020: 奈良県立医科大学, 医学部, 教授 2007 – 2013: Nara Medical University, 医学部, 准教授
Review Section/Research Field	Principal Investigator Emergency medicine / Basic Section 55060:Emergency medicine-related / Basic Section 52010:General internal medicine-related Except Principal Investigator Basic Section 55060:Emergency medicine-related
Keywords	Principal Investigator ADAMTS13 / VWF / von Willebrand factor / mesenteric ischemia / 腸管虚血再灌流傷害 / cancer / 肺がん細胞 / 血管内皮細胞 / UL-VWF / LLC細胞 … More / 腎臓 / 癌 / 血小板 / 癌細胞 / 腎虚血再灌流傷害 / 白血球 / 虚血再灌流傷害 / ischemia/reperfusion / 炎症 / 敗血症 / sepsis / infarction / inflammation / 抗炎症作用 / MCAO / 脳虚血再灌流 / ADAMTS13ノックアウトマウス … More Except Principal Investigator ADAMTS13 / 急性呼吸窮迫症候群 Less

腸管虚血再灌流による腸管傷害・肝傷害の発生・進展に対するADAMTS13の影響Principal Investigator
- Principal Investigator
  
  西尾健治
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Nara Medical University
Effect of ADAMTS13 on pathogenesis of acute respiratory distress syndrome
- Principal Investigator
  
  西村信城
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Nara Medical University
Effect of ADAMTS13/VWF factors on cancer growth and metastasisPrincipal Investigator
- Principal Investigator
  
  NISHIO KENJI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Nara Medical University
Involvement of ADAMTS13 in the pathophysiology of several types of inflammation in the liver and the kidneyPrincipal Investigator
- Principal Investigator
  
  NISHIO KENJI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Nara Medical University
The effect of ADAMTS13 on the pathophysiology of sepsisPrincipal Investigator
- Principal Investigator
  
  NISHIO KENJI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Nara Medical University
Anti-inflammatory and anti-coagulant function of ADAMTS13 expressed under blood flowPrincipal Investigator
- Principal Investigator
  
  NISHIO Kenji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Nara Medical University
Study for the regulation of thrombogenesis by von Willebrand factor cleaving enzymePrincipal Investigator
- Principal Investigator
  
  NISHIO Kenji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Nara Medical University

All 2020 2019 2018 2016 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Functional regulation of von Willebrand factor ameliorates acute ischemia-reperfusion kidney injury in mice2019
- Author(s)
  Shiro Ono, Hideto Matsui, Masashi Noda, Shogo Kasuda, Noritaka Yada, Kiyomi Yoshimoto, Masashi Akiyama, Toshiyuki Miyata, Mitsuhiko Sugimoto & Kenji Nishio
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 14453-14453
- DOI
  10.1038/s41598-019-51013-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07420, KAKENHI-PROJECT-19K08829
[Journal Article] von Willebrand factor aggravates hepatic ischemia-reperfusion injury by promoting neutrophil recruitment in mice2018
- Author(s)
  Urisono Y, Sakata A, Matsui H, Kasuda S, Ono S, Nishio K, Sho M, Okuchi K, Akiyama M, Miyata T, Nishimura S, Sugimoto M
- Journal Title
  
  Thromb Haemost
  
  Volume: 118 Issue: 04 Pages: 700-708
- DOI
  10.1055/s-0038-1636529
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09834, KAKENHI-PROJECT-15K10034, KAKENHI-PROJECT-15K10990, KAKENHI-PROJECT-16K08515
[Journal Article] Ratio of von Willebrand Factor Propeptide to ADAMTS13 Is Associated With Severity of Sepsis.2013
- Author(s)
  Fukushima H, Nishio K, Asai H, Watanabe T, Seki T, Matsui H, Sugimoto M, Matsumoto M, Fujimura Y, Okuchi K.
- Journal Title
  
  Shock.
  
  Volume: 39 Issue: 5 Pages: 409-414
- DOI
  10.1097/shk.0b013e3182908ea7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591069, KAKENHI-PROJECT-23591425, KAKENHI-PROJECT-24592744, KAKENHI-PROJECT-25461456
[Journal Article] ADAMTS13 safeguards the myocardium in a mouse model of acute myocardial infarction.2012
- Author(s)
  Masaaki Doi, Hideto Matsui, Yukiji Takeda, Yoshihiko Saito, Maiko Takeda, Yasunori Matsunari, Kenji Nishio, Midori Shima, Fumiaki Banno, Masashi Akiyama, Koichi Kokame, Toshiyuki Miyata, and Mitsuhiko Sugimoto.
- Journal Title
  
  Thromb. Haemost.
  
  Volume: 108 Issue: 12 Pages: 1236-1238
- DOI
  10.1160/th12-09-0674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570151, KAKENHI-PROJECT-22790923, KAKENHI-PROJECT-23570155, KAKENHI-PROJECT-23659494, KAKENHI-PROJECT-24390250, KAKENHI-PROJECT-24592744
[Journal Article] ADAMTS13 gene deletion enhances plasma high-mobility group box1 elevation and neuroinflammation in brain ischemia-reperfusion iniury2012
- Author(s)
  M.Fujioka, 他16名
- Journal Title
  
  Neurol Sci
  
  Volume: 33 Issue: 5 Pages: 1107-1115
- DOI
  10.1007/s10072-011-0913-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390278, KAKENHI-PROJECT-21592313, KAKENHI-PROJECT-22570151, KAKENHI-PROJECT-22790923, KAKENHI-PROJECT-23590654, KAKENHI-PROJECT-23659494, KAKENHI-PROJECT-24390250
[Journal Article] ADAMTS13欠損マウスを用いた脳虚血再灌流障害の解析2011
- Author(s)
  西尾健治
- Journal Title
  
  血栓と循環
  
  Volume: 19(2) Pages: 250-253
- Data Source
  KAKENHI-PROJECT-21592313
[Journal Article] ADAMTS13 gene deletion aggravates ischemic brain damage : a possible neuroprotective role of ADAMTS13 by ameliorating postischemic hypoperfusion2010
- Author(s)
  Fujioka M, Hayakawa K, Mishima K, Kunizawa A, Irie K, Higuchi S, Nakano T, Muroi C, Fukushima H, Sugimoto M, Banno F, Kokame K, Miyata T, Fujiwara M, Okuchi K, and Nishio K
- Journal Title
  
  Blood
  
  Volume: 115 Pages: 1650-1653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592313
[Journal Article] ADAMTS13の脳梗塞治療薬としての可能性2010
- Author(s)
  西尾健治
- Journal Title
  
  血栓止血誌
  
  Volume: 21(4) Pages: 405-408
- NAID
  10026711784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592313
[Journal Article] 血流下におけるADAMTS13の活性発現機構2008
- Author(s)
  杉本充彦, 志田泰明, 西尾健治
- Journal Title
  
  血液・腫瘍科 56
  
  Pages: 717-723
- NAID
  40019063105
- Data Source
  KAKENHI-PROJECT-19592095
[Journal Article] Functional imaging of shear-dependent activity of ADAMTS13 in regulating mural thrombus growth under whole blood flow conditions2008
- Author(s)
  Yasuaki Shida, Kenji Nishio, (他8名)
- Journal Title
  
  Blood 111
  
  Pages: 1295-1298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592095
[Journal Article] 血流下におけるADAMTS13活性発現機構2008
- Author(s)
  杉本充彦、志田泰明、西尾健治
- Journal Title
  
  血液・腫瘍科 56
  
  Pages: 717-723
- Data Source
  KAKENHI-PROJECT-19592095
[Journal Article] Functional imaging of shear-dependent activity of ADAMTS13 in regulating mural thrombus growth under whole blood flow conditions2008
- Author(s)
  Yasuaki Shida, Kenji Nishio, Mitsuhiko Sugimoto, Tomohiro Mizuno, Masaaki Hamada, Seiji Kato, Masanori Matsumoto, Kazuo Okuchi, Yoshihiro Fujimura and Akira Yoshioka
- Journal Title
  
  Blood 111
  
  Pages: 1295-1298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592095
[Journal Article] Plasma ADAMTS13 activity parallels the APACHE II score, reflecting an early prognostic indicator for patients with severe acute pancreatitis2008
- Author(s)
  Morioka C, Nishio K, (他18名)
- Journal Title
  
  Scand J Gastroenterol 43(11)
  
  Pages: 1387-1396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592095
[Presentation] Soluble fibrin useful for exclusion diagnosis and assessing change of pulmonary embolism2020
- Author(s)
  Noritaka Yada, Makiko Miyamoto, Nobushiro Nishimura, Hiromasa Kawashima, Ryo Yoneima, Yoshiaki Tai, Junko Nakaue, Emiko Tsushima, Kiyomi Yoshimoto, Kenji Nishio
- Organizer
  ISTH 2020 CONGRESS
- Data Source
  KAKENHI-PROJECT-18K07420
[Presentation] Functional Relevance of Von Willebrand Factor in Mouse Model of Hepatic Ischmia-Reperfusion Injury2016
- Author(s)
  Yasuyuki Urisono, Hideto Matui, Shogo Kasuda, Shiro ono, Kenji Nishio, Masashi Akiyama, Toshiyuki Miyata, phD, Kazuo Okuchi and Mitsuhiko Sugimoto
- Organizer
  58th American Society of Hematology Annual Meeting
- Place of Presentation
  San Diego, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10990
[Presentation] 腎虚血再藻流障害マウスモデルにおけるvon Willebrand因子の機能解析2016
- Author(s)
  大野　史郎, 松井　英人, 野田　正志, 粕田　承吾, 瓜園　泰之, 松成　泰典, 矢田　憲孝, 西尾　健治, 杉本　充彦
- Organizer
  第38回日本血栓止血学会学術集会
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-15K10990
[Presentation] A possible new therapeutic strategy with ADAMTS13 for cerebral infarction.2012
- Author(s)
  Kenji Nishio
- Organizer
  SIRIC International Symposium 2012 Perspectives in disease models of the Heart and the Brain of Mice and Men.
- Place of Presentation
  Seoul (Korea)
- Data Source
  KAKENHI-PROJECT-24592744
[Presentation] The Ratio of ADAMTS13 to VWF-Propeptide Can Reflect the Disease Severity and the Extent of Inflammation of the Patients with Severe Sepsis or Septic Shock2011
- Author(s)
  Fukushima H, Nishio K, Watanabe T, Seki T, Matsui H, Sugimoto M, Matsumoto M, Fujimura Y, Okuchi K
- Organizer
  53^<th> American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  San Diego
- Year and Date
  2011-12-12
- Data Source
  KAKENHI-PROJECT-21592313
[Presentation] ADAMTS13の機能-In vitroからマウス脳梗塞モデルまで-2010
- Author(s)
  西尾健治
- Organizer
  第18回奈良脳神経ネットワーク研究会
- Place of Presentation
  奈良県橿原市
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-21592313
[Presentation] TTPとDIC 生体侵襲と血栓止血2010
- Author(s)
  西尾健治
- Organizer
  SIRS-DIC研究会
- Place of Presentation
  宇都宮
- Year and Date
  2010-07-02
- Data Source
  KAKENHI-PROJECT-21592313
[Presentation] 脳梗塞モデルに対するADAMTS13の効果 ―マウスを用いた in vivo 実験系による検討―2009
- Author(s)
  西尾健治
- Organizer
  37回日本救急医学総会
- Place of Presentation
  盛岡
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-21592313
[Presentation] 脳梗塞モデルに対するADAMTS13の効果-マウスを用いたin vivo実験系による検討-2009
- Author(s)
  西尾健治, 藤岡政行, 福島英賢, 植山徹, 坂野史明, 小亀浩市, 宮田敏行, 奥地一夫
- Organizer
  37回日本救急医学総会
- Place of Presentation
  盛岡市
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-21592313
[Presentation] ADAMTS13の神経保護作用-脳虚血再灌流障害マウスモデルを用いて-2009
- Author(s)
  西尾健治、藤岡政行、福島英賢、奥地一夫、坂野史明、小亀浩市、宮田敏行
- Organizer
  第32回日本血栓止血学会学術集会
- Place of Presentation
  小倉
- Year and Date
  2009-06-06
- Data Source
  KAKENHI-PROJECT-21592313
[Presentation] PROTECTIVE PROPERTY OF ADAMTS13 IN A MOUSE-MODEL OF ISCHEMIC STROKE XXII2009
- Author(s)
  K. Nishio, M. Fujioka, K. Hayakawa, K. Mishima, M. Fujiwara, F. Banno, K. Kokame, T. Miyata, Y. Shida, M. Sugimoto, T. Ueyama, H. Fukushima, K. Okuchi
- Organizer
  Congress of The International Society on Thrombosis and Haemostasis
- Place of Presentation
  Boston
- Data Source
  KAKENHI-PROJECT-21592313
[Presentation] Neuroprotective role of ADAMTS13 on ischemia-reperfusion injury2009
- Author(s)
  Kenji Nishio, Masayuki Fujioka, Kazuhide Hayakawa, Kenichi Mishima, Michihiro Fujiwara, Fumiaki Banno, Koichi Kokame, Toshiyuki Miyata, Yasuaki Shida, Mitsuhiko Sugimoto, Hidetada Fukushima, Kazuo Okuchi
- Organizer
  The 14^<th> Meeting on Thrombosis & Rheology
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2009-03-14
- Data Source
  KAKENHI-PROJECT-19592095
[Presentation] PROTECTIVE PROPERTY OF ADAMTS13 IN A MOUSE-MODEL OF ISCHEMIC STROKE2009
- Author(s)
  西尾健治
- Organizer
  XXII International Society on Thrombosis and Haemostasis
- Place of Presentation
  Boston
- Year and Date
  2009-07-14
- Data Source
  KAKENHI-PROJECT-21592313
[Presentation] Functional imaging of shear-dependent activity of ADAMTS13 in regulating mural thrombus growth under whole blood flow conditions2008
- Author(s)
  Shida Y, Nishio K, (他6名)
- Organizer
  5^<th> Conference of the Asian-Pacific society on Thrombosis & Hemostasis
- Place of Presentation
  Singapore
- Year and Date
  2008-09-19
- Data Source
  KAKENHI-PROJECT-19592095
[Presentation] ADAMTS13による脳虚血再潅流障害抑制効果2008
- Author(s)
  西尾健治
- Organizer
  第36回日本救急医学会総会
- Place of Presentation
  札幌
- Year and Date
  2008-10-13
- Data Source
  KAKENHI-PROJECT-19592095
[Presentation] ADAMTS 13 Gene Deletion Aggravates Ischemic Brain Damage2008
- Author(s)
  Nishio K, (他11名)
- Organizer
  50^<th> American Society Of Hematology Annual Meeting
- Place of Presentation
  San Francisco
- Year and Date
  2008-12-08
- Data Source
  KAKENHI-PROJECT-19592095
[Presentation] AMTS13による脳虚血再灌流障害抑制効果2008
- Author(s)
  西尾健治、藤岡政行、福島英賢、奥地一夫、坂野史明、小亀浩市、宮田敏行
- Organizer
  第36回日本救急医学会総会
- Place of Presentation
  北海道札幌市
- Year and Date
  2008-10-13
- Data Source
  KAKENHI-PROJECT-19592095
[Presentation] ADAMTS13 gene deletion aggravates ischemic brain damage2008
- Author(s)
  Kenji Nishio, Masayuki Fujioka, Kazuhide Hayakawa, Kenichi Mishima, Michihiro Fujiwara, Fumiaki Banno, Koichi Kokame, Toshiyuki Miyata, Yasuaki Shida, Mitsuhiko Sugimoto, Hidetada Fukushima, Kazuo Okuchi
- Organizer
  The 50^<th> Annual Meeting of American Society of Hematology
- Place of Presentation
  San Francisco, USA
- Year and Date
  2008-12-08
- Data Source
  KAKENHI-PROJECT-19592095
[Presentation] 血流影響下ADAMTS13活性発現メカニズム2007
- Author(s)
  西尾健治、福島英賢、奥地一夫、志田泰明、杉本充彦、吉岡章
- Organizer
  第35回日本救急医学会総会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2007-10-17
- Data Source
  KAKENHI-PROJECT-19592095
[Presentation] 血流影響下ADAMTS13活性発現メカニズム2007
- Author(s)
  西尾健治
- Organizer
  第35回日本救急医学会総会
- Place of Presentation
  大阪
- Year and Date
  2007-10-17
- Data Source
  KAKENHI-PROJECT-19592095
[Presentation] 血流下でのADAMTS13 による壁血栓成長制御メカニズム-ずり速度との機能連関解析2007
- Author(s)
  志田泰明、杉本充彦、水野智寛、濱田匡章、吉岡章、西尾健治、奥地一夫、加藤誠司、松本雅則、藤村吉博
- Organizer
  第30回日本血栓止血学会学術集会
- Place of Presentation
  三重県志摩市
- Year and Date
  2007-11-16
- Data Source
  KAKENHI-PROJECT-19592095
[Presentation] von Willebrand Factor-Dependent Inflammatory Responses in Mouse Septic Model by Cecal Ligation and Puncture
- Author(s)
  Shogo Kasuda, Hideto Matsui, Shiro Ono, Yasunori Matsunari, Kenji Nishio, Midori Shima, Katsuhiko Hatake and Mitsuhiko Sugimoto
- Organizer
  2014ASH （American Society of Hematology)　meeting
- Place of Presentation
  San Francisco, USA
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-24592744

1. FUKUSHIMA Hidetada (90347568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. 川島浩正 (70865526)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 西村信城 (80865519)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. IMOTO Hitomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 松本雅則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 藤村吉博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 小亀浩市

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 宮田敏行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 秋山正志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nishio Kenji 西尾 健治

西尾 健治 ニシオ ケンジ

NISHIO Kenji 西尾 健治

Research Projects

Research Products

Co-Researchers

腸管虚血再灌流による腸管傷害・肝傷害の発生・進展に対するADAMTS13の影響Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effect of ADAMTS13 on pathogenesis of acute respiratory distress syndrome

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effect of ADAMTS13/VWF factors on cancer growth and metastasisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Involvement of ADAMTS13 in the pathophysiology of several types of inflammation in the liver and the kidneyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effect of ADAMTS13 on the pathophysiology of sepsisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Anti-inflammatory and anti-coagulant function of ADAMTS13 expressed under blood flowPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study for the regulation of thrombogenesis by von Willebrand factor cleaving enzymePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Functional regulation of von Willebrand factor ameliorates acute ischemia-reperfusion kidney injury in mice2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] von Willebrand factor aggravates hepatic ischemia-reperfusion injury by promoting neutrophil recruitment in mice2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ratio of von Willebrand Factor Propeptide to ADAMTS13 Is Associated With Severity of Sepsis.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ADAMTS13 safeguards the myocardium in a mouse model of acute myocardial infarction.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ADAMTS13 gene deletion enhances plasma high-mobility group box1 elevation and neuroinflammation in brain ischemia-reperfusion iniury2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ADAMTS13欠損マウスを用いた脳虚血再灌流障害の解析2011

Author(s)

Journal Title

Data Source

[Journal Article] ADAMTS13 gene deletion aggravates ischemic brain damage : a possible neuroprotective role of ADAMTS13 by ameliorating postischemic hypoperfusion2010

Author(s)

Journal Title

Nishio Kenji 西尾健治

西尾健治ニシオケンジ

NISHIO Kenji 西尾健治