SAKAI Takayuku 坂井隆之

Researcher Number	60260577
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2004 – 2006: 東京歯科大学, 歯学部, 講師 2005: 東京歯科大学, 講師 2002 – 2003: School of Medicine, Department of Oral Surgery, Lecturer, 医学部, 講師 2001: 鶴見大学, 歯学部, 助手
Review Section/Research Field	Principal Investigator Surgical dentistry / Surgical dentistry Except Principal Investigator Functional basic dentistry
Keywords	Principal Investigator Phospholipase D / Apoptosis / Gene Supression / siRNA / Cell Survival / 阻害剤 / Head and Neck Cancer / gene supression / phospholipase D / 頭頚部扁平上皮癌 … More / Gene Supresssion / 頭頚部偏平上皮癌 / Inhibitor / Protein kinase C / Tyrosine kinase / MAP kinase / Oral cancer / Lactoferrin / PKC / PMA / フォスフォリバーゼD / プロテインキナーゼC / チロシンキナーゼ / MAPキナーゼ / フォスフォリパーゼD / 口腔癌 / アポトーシス / ラクトフェリン … More Except Principal Investigator rat / 唾液腺 / 超音波導入法 / in vivo / siRNA Less

個体レベルの唾液腺機能解析の為のsiRNAと超音波を応用した遺伝子抑制法の開発
- Principal Investigator
  
  川口充
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tokyo Dental College
A study of cell survival mechanisms for apoptosis-resistant oral squamous cell carcinoma cell linePrincipal Investigator
- Principal Investigator
  
  SAKAI Takayuki
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  TOKYO DENTAL COLLEGE
  Toho University
Lactoferrin-induced apoptosis and PLD activation in oral squamous cell carcinoma cell linePrincipal Investigator
- Principal Investigator
  
  SAKAI Takayuku
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Toho University
  Tsurumi University

All 2006 2005 2004

All Journal Article

[Journal Article] 【楽の副作用】副作用の薬理薬物治療と口腔内障害2006
- Author(s)
  川口充, 澤木康平, 大久保みぎわ, 坂井隆之, 四宮敬史, 小菅康弘
- Journal Title
  
  日本薬理学雑誌 127・6
  
  Pages: 447-453
- Data Source
  KAKENHI-PROJECT-17659589
[Journal Article] 化学療法薬からの癌細胞のサバイバルメカニズム.2006
- Author(s)
  坂井隆之
- Journal Title
  
  日本薬理学雑誌 127・5
  
  Pages: 342-347
- NAID
  10018061521
- Data Source
  KAKENHI-PROJECT-17659589
[Journal Article] Pepsin-digested Bovine Lactoferrin Induces Apoptotic Cell Death with JNK/SAPK Activation in Oral Cancer Cells.2005
- Author(s)
  Sakai T
- Journal Title
  
  J.Pharmacological Sciences 98・1
  
  Pages: 41-48
- NAID
  10025727859
- Data Source
  KAKENHI-PROJECT-15592137
[Journal Article] Chemotherapy of malignant tumor : Trends in head and Neack malignancy and the potential of post-human genome project to individual medicine.2005
- Author(s)
  Sakai T, Kawaguchi M.
- Journal Title
  
  The Shika Gakuho 105(1)
  
  Pages: 1-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592137
[Journal Article] 悪性腫瘍の化学療法:頭頸部領域での現状とポストゲノム時代のオーダーメイド治療の可能性2005
- Author(s)
  坂井隆之
- Journal Title
  
  歯科学報 105・1
  
  Pages: 1-12
- NAID
  10015424365
- Data Source
  KAKENHI-PROJECT-15592137
[Journal Article] ラクトフェリン酵素分解産物の口腔扁平上皮癌細胞へのアポトーシス誘導と抵抗性.2005
- Author(s)
  坂井隆之
- Journal Title
  
  ミルクサイエンス 53・4
  
  Pages: 254-255
- NAID
  110003163424
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15592137
[Journal Article] 悪性腫瘍の化学療法 : 頭頸部領域での現状とポストゲノム時代のオーダーメイド治療の可能性.2005
- Author(s)
  坂井隆之
- Journal Title
  
  歯科学報 105・1
  
  Pages: 1-12
- NAID
  10015424365
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15592137
[Journal Article] Pepsin-digested Bovine Lactoferrin Induces Apoptotic Cell Death with JNK/SAPK Activation in Oral Cancer Cells.2005
- Author(s)
  Sakai T, Banno Y, Kato Y, Nozawa Y, Kawaguchi M.
- Journal Title
  
  J.Pharmacological Sciences 98(1)
  
  Pages: 41-48
- NAID
  10025727859
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592137
[Journal Article] Pepsin-digested Bovine Lactoferrin Induces Apoptotic Cell Death with JNK/SAPK Activation in Oral Cancer Cells.2005
- Author(s)
  Sakai T
- Journal Title
  
  J. Pharmacological Sciences 98・1
  
  Pages: 41-48
- NAID
  10025727859
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15592137
[Journal Article] Pepsin-digested bovine lactoferrin induces apoptotic cell death and survival mechanism in oral squarmous cell carcinoma cells. (Japanease)2004
- Author(s)
  Sakai T, Kawaguchi M, Sawaki K, Ookubo M, Shinomiya T, Banno Y.
- Journal Title
  
  Milk Science 53(4)
  
  Pages: 254-255
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592137
[Journal Article] Possible involvement of phosphatidiylcholine-specific phospholipase C in prostaglandin F2a-stimulated proliferation in osteoblast-like MC3T3-E1 cells.2004
- Author(s)
  Sakai T, Sugiyama T, Banno Y, Kato Y, Nozawa Y
- Journal Title
  
  J.Bone Mineral Metabolism 22(3)
  
  Pages: 198-206
- Data Source
  KAKENHI-PROJECT-15592137
[Journal Article] Possible involvement of phosphatidiylcholine-specific phospholipase C in prostaglandin F2α-stimulated proliferation in osteoblast-like MC3T3-E1 cells.2004
- Author(s)
  Sakai T, Sugiyama T, Bannno Y, Kato Y, Nozawa Y
- Journal Title
  
  J.Bone Mineral Metabolism 22(3)
  
  Pages: 198-206
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592137
[Journal Article] Possible involvement of phosphatidiylcholine-specific phospholipase C in prostaglandin F2α-stimulated proliferation in osteoblast-like MC3T3-E1 cells.2004
- Author(s)
  Sakai T
- Journal Title
  
  J. Bone Mineral Metabolism 22・3
  
  Pages: 198-206
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15592137

1. 川口充 (20096473)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 大久保みぎわ (40301519)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

SAKAI Takayuku 坂井 隆之

Research Projects

Research Products

Co-Researchers

個体レベルの唾液腺機能解析の為のsiRNAと超音波を応用した遺伝子抑制法の開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study of cell survival mechanisms for apoptosis-resistant oral squamous cell carcinoma cell linePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Lactoferrin-induced apoptosis and PLD activation in oral squamous cell carcinoma cell linePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 【楽の副作用】副作用の薬理 薬物治療と口腔内障害2006

Author(s)

Journal Title

Data Source

[Journal Article] 化学療法薬からの癌細胞のサバイバルメカニズム.2006

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Pepsin-digested Bovine Lactoferrin Induces Apoptotic Cell Death with JNK/SAPK Activation in Oral Cancer Cells.2005

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Chemotherapy of malignant tumor : Trends in head and Neack malignancy and the potential of post-human genome project to individual medicine.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] 悪性腫瘍の化学療法:頭頸部領域での現状とポストゲノム時代のオーダーメイド治療の可能性2005

Author(s)

Journal Title

NAID

Data Source

[Journal Article] ラクトフェリン酵素分解産物の口腔扁平上皮癌細胞へのアポトーシス誘導と抵抗性.2005

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] 悪性腫瘍の化学療法 : 頭頸部領域での現状とポストゲノム時代のオーダーメイド治療の可能性.2005

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Pepsin-digested Bovine Lactoferrin Induces Apoptotic Cell Death with JNK/SAPK Activation in Oral Cancer Cells.2005

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Pepsin-digested Bovine Lactoferrin Induces Apoptotic Cell Death with JNK/SAPK Activation in Oral Cancer Cells.2005

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Pepsin-digested bovine lactoferrin induces apoptotic cell death and survival mechanism in oral squarmous cell carcinoma cells. (Japanease)2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Possible involvement of phosphatidiylcholine-specific phospholipase C in prostaglandin F2a-stimulated proliferation in osteoblast-like MC3T3-E1 cells.2004

Author(s)

Journal Title

Data Source

[Journal Article] Possible involvement of phosphatidiylcholine-specific phospholipase C in prostaglandin F2α-stimulated proliferation in osteoblast-like MC3T3-E1 cells.2004

SAKAI Takayuku 坂井隆之

[Journal Article] 【楽の副作用】副作用の薬理薬物治療と口腔内障害2006