agata yasutosi 縣保年

… Alternative Names

AGATA Yasutoshi 縣保年

Less

Researcher Number	60263141
Other IDs
Affiliation (Current)	2025: 滋賀医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2012 – 2024: 滋賀医科大学, 医学部, 教授 2011 – 2012: 京都大学, 医学(系)研究科(研究院), 准教授 2008 – 2011: Kyoto University, 医学研究科, 准教授 2005 – 2006: 京都大学, 医学研究科, 科学技術振興助教授 2004: 京都大学, 医学研究科, 研究員(科学技術振興)(常勤形態) 1995 – 1998: 京都大学, 遺伝子実験施設, 助手
Review Section/Research Field	Principal Investigator General medical chemistry / Biological Sciences / General medical chemistry / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 49070:Immunology-related / Biological Sciences
Keywords	Principal Investigator 転写因子 / エピジェネティクス / クロマチン / 遺伝子発現 / iPS細胞 / Ｔ細胞受容体（TCR） / 染色体ダイナミクス / CTCF / コヒーシン / Znフィンガー … More / Kruppel / 腫瘍浸潤T細胞 / がん免疫療法 / 遺伝子改変カニクイザル / キラーT細胞 / カセット交換法 / がん抗原 / カセット交換法（RMCE） / CRISPR/Cas9 / ゲノム編集 / E2A / ChIP-Seq / 造血系前駆細胞 / 遺伝子再構成 / 対立遺伝子排除 / 免疫学 / 発現制御 / 遺伝子 / Anchored PCR / RT-PCR / lipopolysaccharide / B細胞分化 / Ｔ細胞受容体（TCR）遺伝子 / TCR-iPS細胞 / T-iPS細胞 / がん免疫細胞療法 / Cre/loxP / 再生医療 / がん免疫 / T細胞受容体 / がんモデル動物 / カセット交換法　RMCE / RMCE / カセット交換法 RMCE / 腫瘍浸潤リンパ球（TIL） / カニクイザル / immunology / differentiation / development / regulation of expression / genome / gene / 発生・分化 / ゲノム / Id3 / 転写因子 foci / 3C assay / 3D-DNA FISH / 転写因子foci / Immuno-FISH / 3D-FISH / 転写因子ファクトリー / 染色体ルーピング / 染色体高次構造 / 核内構造体 / Mediator / 3C アッセイ / インシュレーター / 染色体構造変化 / Rad21 / E2A転写因子 / エピジェネテクス / 癌 / 感染症 / KAP-1 / Leucin rich repeat(LeR) / co-repressor / KAP-1(KRAB Associated Protein-1) / Kruppel associated box(KRAB) / 転写調節 / 転写抑制 / Interleukin-4 / interleukin-4 … More Except Principal Investigator Multiple isotype expression / trans-mRNA / trans-splicing / germ-line transcript / Gene rearrangement / S region / Ig gene / Ig class Switching / CD40リガンド / アレルギー / 多重アイソタイプ同時発現 / トランスmRNA / トランス・スプライシング / 非組換え型転写 / 遺伝子組換え / S領域 / 抗体遺伝子 / 抗体クラス変換 Less

Development of cancer immunotherapy using T cells regenerated from iPS cells and cynomolgus macaque cancer modelsPrincipal Investigator
- Principal Investigator
  
  縣保年
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Shiga University of Medical Science
Development of cancer immunotherapy using T cells regenerated from iPS cells and genetically modified cynomolgus macaquePrincipal Investigator
- Principal Investigator
  
  縣保年
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Shiga University of Medical Science
Development of cancer immunotherapy using T cells regenerated from iPS cells and genetically engineered monkeysPrincipal Investigator
- Principal Investigator
  
  Agata Yasutoshi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Shiga University of Medical Science
Efficient regeneration of tumor-specific cytotoxic lymphocytes using the iPSC technology and genome editingPrincipal Investigator
- Principal Investigator
  
  AGATA YASUTOSHI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Shiga University of Medical Science
Purification of the functional transcription factor complex and analyses of the factors that constitute the complexPrincipal Investigator
- Principal Investigator
  
  Agata Yasutoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Shiga University of Medical Science
コヒーシンによる染色体構造変化を介した造血細胞分化の制御機構Principal Investigator
- Principal Investigator
  
  縣保年
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Shiga University of Medical Science
  Kyoto University
Novel epigenetic regulation of the gene expression program by chromosome dynamicsPrincipal Investigator
- Principal Investigator
  
  AGATA YASUTOSHI
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Shiga University of Medical Science
  Kyoto University
抗原受容体遺伝子の対立遺伝子排除による自己形成の分子基盤Principal Investigator
- Principal Investigator
  
  縣保年
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
TCR遺伝子の対立遺伝子排除による自己形成の分子基盤Principal Investigator
- Principal Investigator
  
  縣保年
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Regulatory mechanisms of allelic exclusion by epigenetics and chromosome dynamicsPrincipal Investigator
- Principal Investigator
  
  AGATA Yasutoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
Elucidation of the epigenetic regulation of the antigen receptor gene rearrangementPrincipal Investigator
- Principal Investigator
  
  AGATA Yasutoshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
体細胞突然変異の遺伝子部位特異的な導入機構Principal Investigator
- Principal Investigator
  
  縣保年
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Znフィンガー因子の系統的遺伝子単離と転写調節における機能の解析Principal Investigator
- Principal Investigator
  
  縣保年
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
B細胞の分化初期に発現するZnフィンガー因子の遺伝子単離と解析Principal Investigator
- Principal Investigator
  
  縣保年
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
B細胞の初期分化を制御するZnフィンガー因子の遺伝子単離と解析Principal Investigator
- Principal Investigator
  
  縣保年
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
Regulation of RNA processing in B lymphocyte differentiation
- Principal Investigator
  
  SHIMIZU Akira
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  KYOTO UNIVERSITY

[Book] 標準免疫学第4版2021
- Author(s)
  宮坂昌之（執筆分担者　縣　保年）
- Total Pages
  434
- Publisher
  医学書院
- ISBN
  9784260042383
- Data Source
  KAKENHI-PROJECT-18K07171
[Journal Article] Isolation of TCR genes with tumor-killing activity from tumor-infiltrating and circulating lymphocytes in a tumor rejection cynomolgus macaque model2022
- Author(s)
  Terada Koji、Kondo Kenta、Ishigaki Hirohito、Nagashima Ayaka、Satooka Hiroki、Nagano Seiji、Masuda Kyoko、Kawamura Teruhisa、Hirata Takako、Ogasawara Kazumasa、Itoh Yasushi、Kawamoto Hiroshi、Agata Yasutoshi
- Journal Title
  
  Molecular Therapy - Oncolytics
  
  Volume: 24 Pages: 77-86
- DOI
  10.1016/j.omto.2021.12.003
- NAID
  120007182844
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07171, KAKENHI-PROJECT-19K07621, KAKENHI-PROJECT-19H01140, KAKENHI-PROJECT-19K07712, KAKENHI-PROJECT-20K22840
[Journal Article] Regeneration of Tumor-Antigen-Specific Cytotoxic T Lymphocytes from iPSCs Transduced with Exogenous TCR Genes2020
- Author(s)
  Maeda Takuya、Nagano Seiji、Kashima Soki、Terada Koji、Agata Yasutoshi、Ichise Hiroshi、Ohtaka Manami、Nakanishi Mahito、Fujiki Fumihiro、Sugiyama Haruo、Kitawaki Toshio、Kadowaki Norimitsu、Takaori-Kondo Akifumi、Masuda Kyoko、Kawamoto Hiroshi
- Journal Title
  
  Molecular Therapy - Methods & Clinical Development
  
  Volume: 19 Pages: 250-260
- DOI
  10.1016/j.omtm.2020.09.011
- NAID
  120007169387
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07712, KAKENHI-ORGANIZER-19H05739, KAKENHI-PROJECT-18K07171
[Journal Article] Cytotoxic T lymphocytes regenerated from iPS cells have therapeutic efficacy in a patient-derived xenograft solid tumor model.2020
- Author(s)
  Kashima S, Maeda T, Masuda K, Nagano S, Inoue T, Takeda M, Kono Y, Kobayashi T, Saito S, Higuchi T, Ichise H, Kobayashi Y, Iwaisako K, Terada K, Agata Y, Nakamura K, Saito M, Narita S, Ogawa O, Habuchi T, Kawamoto H.
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 4 Pages: 100998-100998
- DOI
  10.1016/j.isci.2020.100998
- NAID
  120006826710
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07171, KAKENHI-PROJECT-18J10676, KAKENHI-PROJECT-19K07712, KAKENHI-PROJECT-20K08996, KAKENHI-ORGANIZER-19H05739, KAKENHI-PROJECT-16H02679, KAKENHI-PROJECT-18H02839
[Journal Article] Characterization of tumour-infiltrating lymphocytes in a tumour rejection cynomolgus macaque model2020
- Author(s)
  Satooka Hiroki、Ishigaki Hirohito、Todo Kagefumi、Terada Koji、Agata Yasutoshi、Itoh Yasushi、Ogasawara Kazumasa、Hirata Takako
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 8414-8414
- DOI
  10.1038/s41598-020-65488-x
- NAID
  120006862372
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15183, KAKENHI-PROJECT-19K07621, KAKENHI-PROJECT-19K07712, KAKENHI-PROJECT-19H03148, KAKENHI-PROJECT-18K07171
[Journal Article] Long non-coding RNA MANCR is a target of BET bromodomain protein BRD4 and plays a critical role in cellular migration and invasion abilities of prostate cancer.2020
- Author(s)
  Nagasawa M, Tomimatsu K, Terada K, Kondo K, Miyazaki K, Miyazaki M, Motooka D, Okuzaki D, Yoshida T, Kageyama S, Kawamoto H, Kawauchi A, Agata Y.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 526 Issue: 1 Pages: 128-134
- DOI
  10.1016/j.bbrc.2020.03.043
- NAID
  120006839258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07171, KAKENHI-PROJECT-18K09192, KAKENHI-PROJECT-19K07664, KAKENHI-PROJECT-19K07712
[Journal Article] Three-step transcriptional priming that drives the commitment of multipotent progenitors toward B cells2018
- Author(s)
  Miyai Tomohiro、Takano Junichiro、Endo Takaho A.、Kawakami Eiryo、Agata Yasutoshi、Motomura Yasutaka、Kubo Masato、Kashima Yukie、Suzuki Yutaka、Kawamoto Hiroshi、Ikawa Tomokatsu
- Journal Title
  
  Genes & Development
  
  Volume: 32 Issue: 2 Pages: 112-126
- DOI
  10.1101/gad.309575.117
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0196, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17H04214, KAKENHI-PROJECT-16K15215, KAKENHI-PROJECT-18K07171
[Journal Article] The identification of D-tryptophan as a bioactive substance for postembryonic ovarian development in the planarian Dugesia ryukyuensis.2017
- Author(s)
  Kazuya Kobayashi, Takanobu Maezawa, Hiroyuki Tanaka, Hiroyuki Onuki, Yurie Horiguchi, Hiroshi Hirota, Tetsuo Ishida, Kihachiro Horiike, Yasutoshi Agata, Manabu Aoki, Motonori Hoshi, Midori Matsumoto
- Journal Title
  
  Scientific reports
  
  Volume: 7 Issue: 1 Pages: 45175-45175
- DOI
  10.1038/srep45175
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01249, KAKENHI-PROJECT-26440180, KAKENHI-PROJECT-15K07121, KAKENHI-PROJECT-16K15215
[Journal Article] The Effect of D-Aspartate on Spermatogenesis in Mouse Testis.2016
- Author(s)
  Tomita K, Tanaka H, Kageyama S, Nagasawa M, Wada A, Murai R, Kobayashi K, Hanada E, Agata Y, Kawauchi A
- Journal Title
  
  Biol Reprod.
  
  Volume: 30 Issue: 2 Pages: 1-7
- DOI
  10.1095/biolreprod.115.134692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670136, KAKENHI-PROJECT-16K15215
[Journal Article] Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of the B-lineage program.2016
- Author(s)
  Ikawa T, Masuda K, Endo TA, Endo M, Isono K, Koseki Y, Nakagawa R, Kometani K, Takano J, Agata Y, Katsura Y, Kurosaki T, Vidal M, Koseki H, Kawamoto H.
- Journal Title
  
  Genes. Dev.
  
  Volume: 30 Issue: 22 Pages: 2475-2485
- DOI
  10.1101/gad.290593.116
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221306, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-15H04743, KAKENHI-PROJECT-26670136, KAKENHI-PROJECT-16K07372, KAKENHI-PROJECT-16K09870, KAKENHI-PROJECT-16K15289, KAKENHI-PROJECT-16K15215
[Journal Article] Induced Developmental Arrest of Early Hematopoietic Progenitors Leads to the Generation of Leukocyte Stem Cells.2015
- Author(s)
  Ikawa T, Masuda K, Huijskens M.J.A.J., Satoh R, Kakugawa K, Agata Y, Miyai T, Germeraad W.T.V., Katsura Y, Kawamoto H.
- Journal Title
  
  Stem Cell Reports
  
  Volume: 5 Issue: 5 Pages: 716-727
- DOI
  10.1016/j.stemcr.2015.09.012
- NAID
  120005745636
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670136
[Journal Article] Crucial role of the Rap G protein signal in Notch activation and leukemogenicity of T-cell acute lymphoblastic leukemia.2015
- Author(s)
  Doi K, Imai T, Kressler C, Yagita H, Agata Y, Vooijs M, Hamazaki Y, Inoue J, Minato N.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Issue: 1 Pages: 7978-7985
- DOI
  10.1038/srep07978
- NAID
  120005555511
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390068, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-26460066, KAKENHI-PROJECT-26670136, KAKENHI-PROJECT-15K15151, KAKENHI-PUBLICLY-25111505, KAKENHI-PROJECT-24590580, KAKENHI-PLANNED-24111008
[Journal Article] The E-Id protein axis modulates the activities of the PI3K-AKT-mTORC1-Hif1a and c-myc/p19Arf pathways to suppress innate variant TFH cell development, thymocyte expansion, and lymphomagenesis.2015
- Author(s)
  Miyazaki M, Miyazaki K, Chen S, Chandra V, Wagatsuma K, Agata Y, Rodewald HR, Saito R, Chang AN, Varki N, Kawamoto H, Murre C.
- Journal Title
  
  Genes Dev.
  
  Volume: 29 Issue: 4 Pages: 409-425
- DOI
  10.1101/gad.255331.114
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390068, KAKENHI-PROJECT-26670136
[Journal Article] Immunohistochemical localization of d-serine dehydratase in chicken tissues.2014
- Author(s)
  Nishimura Y, Tanaka H, Ishida T, Imai S, Matsusue Y, Agata Y, Horiike K.
- Journal Title
  
  Acta Histochem.
  
  Volume: in press Issue: 5 Pages: 244-4
- DOI
  10.1016/j.acthis.2013.12.011
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23118515, KAKENHI-PROJECT-24590351, KAKENHI-PROJECT-25460684
[Journal Article] High expression of nuclear factor 90 (NF90) leads to mitochondrial degradation in skeletal and cardiac muscles2013
- Author(s)
  Takuma Higuchi
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 8 Pages: e43340-e43340
- DOI
  10.1371/journal.pone.0043340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J10660, KAKENHI-PROJECT-12J10665, KAKENHI-PUBLICLY-23118515, KAKENHI-PROJECT-23390068, KAKENHI-PROJECT-23590979, KAKENHI-PROJECT-24590903
[Journal Article] Imatinib mesylate directly impairs class switch recombination through downregulation of AID.2012
- Author(s)
  Kawamata T, Lu J, Sato T, Tanaka M, Nagaoka H, Agata Y, Toyoshima T, Yokoyama K, Oyaizu N, Nakamura N, Ando K, Tojo A, Kotani A
- Journal Title
  
  Blood
  
  Volume: 119 Issue: 13 Pages: 3123-3127
- DOI
  10.1182/blood-2011-01-327932
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021021, KAKENHI-PROJECT-22790904, KAKENHI-PUBLICLY-23118507, KAKENHI-PUBLICLY-23118513, KAKENHI-PUBLICLY-23118515, KAKENHI-PROJECT-23390068, KAKENHI-PROJECT-23591373, KAKENHI-PROJECT-23659151, KAKENHI-PROJECT-24390248
[Journal Article] Reciprocal control of G1-phase progression is required for Th-POK/Runx3-mediated CD4/8 thymocyte cell fate decision.2012
- Author(s)
  Sato T, Chiba T, Ohno S, Sato C, Sugoh T, Miyashita K, Akatsuka H, Hozumi K, Okada Y, Iida Y, Akatsuka A, Agata Y, Chiba M, Kohu K, Satake M, Tanabe H, Saya H, Habu S.
- Journal Title
  
  J Immunol.
  
  Volume: 189 Issue: 9 Pages: 4426-4436
- DOI
  10.4049/jimmunol.1102748
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23118515, KAKENHI-PROJECT-23390068, KAKENHI-PUBLICLY-23118529
[Journal Article] E2A and CBP/p300 act in synergy to promote chromatin accessibility of the immunoglobulin | locus.2012
- Author(s)
  Sakamoto, S., ffakae, K., Anzai, Y., Murai, K., Tamaki, N., Miyazaki, M., Miyazaki, K., Romanow, W. J., Ikawa, T., Kitamura, D., Yanagihira, I., Minato, N., Murre, C., Agata, Y
- Journal Title
  
  J. Immunol
  
  Volume: 188 Issue: 11 Pages: 5547-5560
- DOI
  10.4049/jimmunol.1002346
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19059008, KAKENHI-PROJECT-22390097, KAKENHI-PUBLICLY-23118515, KAKENHI-PROJECT-23390068, KAKENHI-PROJECT-23591609, KAKENHI-PLANNED-24111008, KAKENHI-PROJECT-24659225, KAKENHI-PROJECT-24689042, KAKENHI-ORGANIZER-24111001
[Journal Article] Claudin-4 induction by E-protein activity in later stages of CD4/8double-positive thymocytes to increase positive selection efficiency.2011
- Author(s)
  Kawai Y, Hamazaki Y, Fujita H, Fujita A, Sato T, Furuse M, Fujimoto T, Jetten AM, Agata Y, Minato N.
- Journal Title
  
  Proc Natl Acad Sci USA.
  
  Volume: 108 Pages: 4075-4080
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590298
[Journal Article] Regulation of TCR Vγ2 gene rearrangement by the helix-loop-helix protein, E2A.2011
- Author(s)
  Nozaki M, Wakae K, Tamaki N, Sakamoto S, Ohnishi K, Uejima T, Minato N, Yanagihara I, Agata Y.
- Journal Title
  
  Int Immunol.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590298
[Journal Article] Regulation of TCR Vγ2 gene rearrangement by the helix-loop-helix protein, E2A2011
- Author(s)
  Nozaki M, Wakae K, Tamaki N, Sakamoto S, Ohnishi K, Uejima T, Minato N, Yanagihara I, Agata Y
- Journal Title
  
  Int Immunol
  
  Volume: 23 Pages: 297-305
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021021
[Journal Article] Claudin-4 induction by E-protein activity in later stages of CD4/8 double-positive thymocytes to increase positive selection efficiency2011
- Author(s)
  Kawai Y, Hamazaki Y, Fujita H, Fujita A, Sato T, Furuse M, Fujimoto T, Jetten AM, Agata Y, Minato N
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 108 Pages: 4075-4080
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021021
[Journal Article] The opposing roles of the transcription factor E2A and its antagonist Id3 that orchestrate and enforce the naive fate of T cells.2011
- Author(s)
  Miyazaki M, Rivera RR, Miyazaki K, Lin YC, Agata Y, Murre C
- Journal Title
  
  Nat Immunol.
  
  Volume: 12 Issue: 10 Pages: 992-1001
- DOI
  10.1038/ni.2086
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021021, KAKENHI-PUBLICLY-23118515, KAKENHI-PROJECT-23390068
[Journal Article] Regulation of TCR Vγ2 gene rearrangement by the helix-loop-helix protein, E2A.2011
- Author(s)
  Nozaki M, Wakae K, Tamaki N, Sakamoto S, Ohnishi K, Uejima T, Minato N, Yanagihara I, Agata Y
- Journal Title
  
  I lit Immunol.
  
  Volume: 23 Issue: 5 Pages: 297-305
- DOI
  10.1093/intimm/dxr005
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021021, KAKENHI-PUBLICLY-23118515, KAKENHI-PROJECT-23591609
[Journal Article] The NF90-NF45 complex functions as a negative regulator in the microRNA processing pathway.2009
- Author(s)
  Sakamoto S, Aoki K, Higuchi T, Todaka H, Morisawa K, Tamaki N, Hatano E, Fukushima A, Taniguchi T, Agata Y.
- Journal Title
  
  Mol.Cell.Biol. 29
  
  Pages: 3754-3769
- NAID
  120001756537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590298
[Journal Article] 転写因子E2AとTCRβ遺伝子の対立遺伝子排除2009
- Author(s)
  縣保年
- Journal Title
  
  医学のあゆみ 228
  
  Pages: 1126-1127
- Data Source
  KAKENHI-PROJECT-20590298
[Journal Article] 転写因子E2AとTCRβ遺伝子の対立遺伝子排除2009
- Author(s)
  縣保年
- Journal Title
  
  医学のあゆみ 228(11)
  
  Pages: 1126-1127
- Data Source
  KAKENHI-PROJECT-20590298
[Journal Article] The NF90-NF45 complex functions as a negative regulator in the microRNA processing pathway.2009
- Author(s)
  Sakamoto S, Aoki K, Higuchi T, Todaka H, Morisawa K, Tamaki N, Hatano E, Fukushima A, Taniguchi T, Agata Y.
- Journal Title
  
  Mol Cell Biol 29
  
  Pages: 3754-3769
- NAID
  120001756537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590298
[Journal Article] The NF90-NF45 complex functions as a negative regulator in the microRNA processing pathway.2009
- Author(s)
  Sakamoto S, Aoki K, Higuchi T, Todaka H, Morisawa K, Tamaki N, Hatano E, Fukushima A, Taniguchi T, Agata Y.
- Journal Title
  
  Mol Cell Biol 29
  
  Pages: 3754-3769
- NAID
  120001756537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060040
[Journal Article] 転写因子E2AとTCRβ遺伝子の対立遺伝子排除2009
- Author(s)
  縣保年
- Journal Title
  
  医学のあゆみ 286
  
  Pages: 1126-11271
- Data Source
  KAKENHI-PROJECT-20060040
[Journal Article] E2AはT細胞抗原受容体遺伝子の再構成と対立遺伝子排除を制御する2008
- Author(s)
  縣保年
- Journal Title
  
  細胞工学 27(3)
  
  Pages: 258-259
- Data Source
  KAKENHI-PROJECT-20590298
[Journal Article] Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion.2008
- Author(s)
  Kitao, H., Kimura, M., Yamamoto, K., Seo, H., Namikoshi, K., Agata, Y., Ohta, K., Takata, M.
- Journal Title
  
  Int.Immunol. 20
  
  Pages: 277-284
- NAID
  10021239538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590298
[Journal Article] Spontaneous Large-scale Lymphoid Neogenesis and Balanced Autoimmunity versus Tolerance in the Stomach of H+/K+-ATPase-reactive TCR Transgenic Mouse.2006
- Author(s)
  Katakai, T., Nomura, T., Gonda, H., Sugai, M., Agata, Y., Nishio, A., Masuda, T., Sakaguchi, S., Shimizu, A.
- Journal Title
  
  J. Immunol. 177
  
  Pages: 7858-7867
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590246
[Journal Article] Spontaneous Large-scale Lymphoid Neogenesis and Balanced Autoimmunity versus Tolerance in the Stomach of H^+/K^+-ATPase-reactive TCR Transgenic Mouse.2006
- Author(s)
  Katakai, T., Nomura, T., Gonda, H., Sugai, M., Agata, Y., Nishio, A., Masuda, T., Sakaguchi, S., Shimizu, A.
- Journal Title
  
  J. Immunol. 177
  
  Pages: 7858-7867
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590246
[Journal Article] Direct interaction of NRSF with TBP : chromatin reorganization and core promoter repression for neuron-specific gene transcription.2004
- Author(s)
  Murai K, Naruse Y, Shaul Y, Agata Y, Mori N.
- Journal Title
  
  Nucleic Acids Res. 32
  
  Pages: 3180-3189
- Data Source
  KAKENHI-PROJECT-16017248
[Journal Article] クロマチン修飾によるTリンパ球の抗原レセプター遺伝子組換え制御2004
- Author(s)
  縣保年
- Journal Title
  
  分子細胞治療 3
  
  Pages: 203-211
- Data Source
  KAKENHI-PROJECT-16017248
[Patent] 特異性部位交換可能なエフェクター細胞の製造方法2020
- Inventor(s)
  河本　宏、永野誠治、増田喬子、縣　保年、寺田晃士、近藤健太
- Industrial Property Rights Holder
  河本　宏、永野誠治、増田喬子、縣　保年、寺田晃士、近藤健太
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-18K07171
[Patent] 外来抗原レセプター遺伝子導入細胞の製造方法2018
- Inventor(s)
  河本　宏、永野誠治、増田喬子、縣　保年、寺田晃士
- Industrial Property Rights Holder
  河本　宏、永野誠治、増田喬子、縣　保年、寺田晃士
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-16K15215
[Patent] 外来抗原レセプター遺伝子導入細胞の製造方法2018
- Inventor(s)
  河本　宏、永野誠治、増田喬子、縣　保年、寺田晃士
- Industrial Property Rights Holder
  河本　宏、永野誠治、増田喬子、縣　保年、寺田晃士
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18K07171
[Presentation] カニクイザルの腫瘍浸潤T細胞から腫瘍殺傷能をもつTCR遺伝子を単離する2021
- Author(s)
  近藤健太、寺田晃士、石垣宏仁、長嶋彩花、里岡大樹、永野誠治、増田喬子、川村晃久、平田多佳子、小笠原一誠、伊藤　靖、河本　宏、縣　保年
- Organizer
  第30回 Kyoto T Cell Conference、2021年10月8-9日
- Data Source
  KAKENHI-PROJECT-18K07171
[Presentation] “TCRカセット法”の開発 : がん抗原特異的TCR遺伝子を内在性TCR遺伝子座へ効率よく導入する2021
- Author(s)
  寺田晃士、永野誠治、近藤健太、増田喬子、河本　宏、縣　保年
- Organizer
  第30回 Kyoto T Cell Conference、2021年10月8-9日
- Data Source
  KAKENHI-PROJECT-18K07171
[Presentation] Development of “TCR cassette method”: Regeneration of CTLs from iPSCs in which tumor-antigen specific TCR genes can be efficiently introduced into the endogenous TCR locus by cassette exchange2021
- Author(s)
  Koji Terada, Kenta Kondo, Seiji Nagano, Kyoko Masuda, Hiroshi Kawamoto, Yasutoshi Agata
- Organizer
  第50回日本免疫学会学術集会、奈良、2021年12月8-10日
- Data Source
  KAKENHI-PROJECT-18K07171
[Presentation] Isolation of TCR genes with tumor-killing activity from tumor-infiltrating lymphocytes in a tumor rejection cynomolgus macaque model2021
- Author(s)
  Koji Terada, Kenta Kondo, Hirohito Ishigaki, Ayaka Nagashima, Hiroki Satooka, Seiji Nagano, Kyoko Masuda, Teruhisa Kawamura, Takako Hirata, Kazumasa Ogasawara, Yasushi Itoh, Hiroshi Kawamoto, Yasutoshi Agata
- Organizer
  第50回日本免疫学会学術集会、奈良、2021年12月8-10日
- Data Source
  KAKENHI-PROJECT-18K07171
[Presentation] Vitamin C alters gene expression of CD8+ T cells through DNA demethylation2021
- Author(s)
  Kenta Kondo, Tatsuya Hasegawa, Koji Terada, Yasutoshi Agata
- Organizer
  第50回日本免疫学会学術集会、奈良、2021年12月8-10日
- Data Source
  KAKENHI-PROJECT-18K07171
[Presentation] カニクイザルの腫瘍拒絶モデルにおける腫瘍浸潤T細胞からの腫瘍殺傷能をもつTCR遺伝子の単離.2020
- Author(s)
  寺田晃士、石垣宏仁、近藤健太、長嶋彩花、里岡大樹、永野誠治、増田喬子、川村晃久、河本　宏、平田多佳子、小笠原一誠、伊藤　靖、縣　保年．
- Organizer
  第43回日本分子生物学年会
- Data Source
  KAKENHI-PROJECT-18K07171
[Presentation] ゲノム編集とカセット交換法を用いたがん抗原特異的TCR遺伝子導入法の開発.2020
- Author(s)
  寺田晃士、近藤遼平、永野誠治、前田卓也、増田喬子、河本　宏、縣　保年．
- Organizer
  第24回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K07171
[Presentation] TCRカセット法”の開発：がん抗原特異的TCR遺伝子を内在性TCR遺伝子座へ効率よく導入できるiPS細胞から細胞傷害性T細胞を再生する.2020
- Author(s)
  寺田晃士、近藤健太、永野誠治、増田喬子、河本　宏、縣　保年．
- Organizer
  第43回日本分子生物学年会
- Data Source
  KAKENHI-PROJECT-18K07171
[Presentation] カニクイザルの腫瘍浸潤T細胞から腫瘍殺傷能を有するTCR遺伝子を単離する.2020
- Author(s)
  寺田晃士、近藤健太、石垣宏仁、里岡大樹、永野誠治、増田喬子、平田多佳子、小笠原一誠、伊藤　靖、河本　宏、縣　保年．
- Organizer
  第24回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K07171
[Presentation] PD-1 研究における「点と点」～iPS 細胞とカニクイザルを用いたがん免疫療法の開発2020
- Author(s)
  縣　保年
- Organizer
  日本マイコプラズマ学会誌　特別講演
- Invited
- Data Source
  KAKENHI-PROJECT-18K07171
[Presentation] iPS細胞由来の再生T細胞とカニクイザルを用いたがん免疫療法の開発2020
- Author(s)
  縣　保年
- Organizer
  第５回イムノロジーフォーラム奈良
- Invited
- Data Source
  KAKENHI-PROJECT-18K07171
[Presentation] PD-1研究における「点と点」～iPS細胞を用いたがん特異的T細胞の再生．2019
- Author(s)
  縣　保年
- Organizer
  第26回大阪母子医療センターシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18K07171
[Presentation] Generation of CTLs from iPSCs transduced with TCR genes: development of “TCR cassette” method.2019
- Author(s)
  永野誠治、寺田晃士、近藤遼平、縣　保年、増田喬子、河本　宏．
- Organizer
  第48回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K07171
[Presentation] Development of an efficient method to introduce TCR genes into the endogenous TCR locus by genome editing and cassette exchange.2019
- Author(s)
  寺田晃士、近藤遼平、永野誠治、増田喬子、河本　宏、縣　保年．
- Organizer
  第48回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K07171
[Presentation] iPS 細胞から再生した T 細胞とカニクイザルを用いたがん免疫療法の開発．2019
- Author(s)
  縣　保年
- Organizer
  令和元年度「5大学連携医療フォーラム」
- Invited
- Data Source
  KAKENHI-PROJECT-18K07171
[Presentation] がん抗原特異的なTCR遺伝子を内在性TCR遺伝子座へ効率よく導入する方法の確立2018
- Author(s)
  寺田晃士、近藤遼平、永野誠治、増田喬子、河本　宏、縣　保年
- Organizer
  第41回日本分子生物学会（2018年11月28日, 横浜）
- Data Source
  KAKENHI-PROJECT-16K15215
[Presentation] がん抗原特異的なTCR遺伝子を内在性TCR遺伝子座へ効率よく導入する方法の確立2018
- Author(s)
  寺田晃士、近藤遼平、永野誠治、増田喬子、河本　宏、縣　保年
- Organizer
  第41回日本分子生物学会（2018年11月28日, 横浜）
- Data Source
  KAKENHI-PROJECT-18K07171
[Presentation] E2A and CBP/p300 regulate chromosome dynamics of the TCRβ locus.2017
- Author(s)
  Agata, Y, Wagatsuma K, Terada K, Tanaka H, Ikawa T, Masuda K, Kawamoto H, Kimura H
- Organizer
  7th International Workshop of Kyoto T Cell Conference
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2017-03-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670136
[Presentation] E2A and CBP/p300 regulate chromosome dynamics of the TCRβ locus.2017
- Author(s)
  Agata, Y, Wagatsuma K, Terada K, Tanaka H, Ikawa T, Masuda K, Kawamoto H, Kimura H
- Organizer
  7th International Workshop of Kyoto T Cell Conference
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2017-03-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15215
[Presentation] E2A転写因子とCBP/p300の核内構造体によるTCRβ遺伝子の染色体ダイナミクス．2017
- Author(s)
  寺田晃士、我妻慶祐、永澤誠之、田中裕之、門田健明、伊川友活、増田喬子、河本　宏、縣　保年．
- Organizer
  第64回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-16K15215
[Presentation] 画像処理技術を用いた核内蛋白質構造体の間隙空間容量測定プログラムの作成．2017
- Author(s)
  門田健明，我妻慶祐，寺田晃士，永澤誠之，田中裕之，内田誠一，縣　保年．
- Organizer
  第64回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-16K15215
[Presentation] E2A 転写因子 foci を足場とした T 細胞受容体遺伝子座の染色体ダイナミクス.2016
- Author(s)
  縣　保年、我妻慶祐、寺田晃士、安齋悠樹、田中裕之、伊川友活、増田喬子、河本　宏、木村　宏
- Organizer
  第10回日本エピジェネティクス研究会年会
- Place of Presentation
  豊中市
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-26670136
[Presentation] 転写因子E2AとCBP/p300が形成する核内構造体を足場としたTCRβ遺伝子再構成の制御機構.2016
- Author(s)
  寺田晃士、我妻慶祐、田中裕之、伊川友活、増田喬子、河本　宏、縣　保年
- Organizer
  第26回 Kyoto T Cell Conference
- Place of Presentation
  京都市
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-26670136
[Presentation] E2A 転写因子 foci を足場とした T 細胞受容体遺伝子座の染色体ダイナミクス.2016
- Author(s)
  縣　保年、我妻慶祐、寺田晃士、安齋悠樹、田中裕之、伊川友活、増田喬子、河本　宏、木村　宏
- Organizer
  第10回日本エピジェネティクス研究会年会
- Place of Presentation
  豊中市
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-16K15215
[Presentation] 転写因子E2AとCBP/p300が形成する核内構造体を足場としたTCRβ遺伝子再構成の制御機構.2016
- Author(s)
  寺田晃士、我妻慶祐、田中裕之、伊川友活、増田喬子、河本　宏、縣　保年
- Organizer
  第26回 Kyoto T Cell Conference
- Place of Presentation
  京都市
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-16K15215
[Presentation] E2A転写因子ファクトリーを足場としたTCRβ遺伝子の染色体ダイナミクス2015
- Author(s)
  我妻慶祐、寺田晃士、安齋悠樹、田中裕之、伊川友活、増田喬子、河本　宏、湊　長博、縣　保年
- Organizer
  第25回 Kyoto T Cell Conference
- Place of Presentation
  京都市
- Year and Date
  2015-05-15
- Data Source
  KAKENHI-PROJECT-26670136
[Presentation] 発生段階特異的なTCRγ遺伝子再構成における転写抑制因子Gfi-1の役割2011
- Author(s)
  若江亨祥、坂本修士、山下政克、中山俊憲、湊長博、縣保年
- Organizer
  第19回Kyoto T Cell Conference
- Place of Presentation
  京都
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PUBLICLY-22021021
[Presentation] 発生段階特異的なTCRγ遺伝子再構成における転写抑制因子Gfi-1の役割2011
- Author(s)
  若江亨祥、坂本修士、山下政克、中山俊憲、湊長博、縣保年
- Organizer
  第19回Kyoto T Cell Conference
- Place of Presentation
  日本、京都
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PROJECT-23390068
[Presentation] E2A and CBP/p300 act in synergy to promote chromatin accessibility of the immunoglobulin κlocus in nonlymphoid cells.2010
- Author(s)
  縣保年
- Organizer
  Gene Expression & Signaling in the Immune System
- Place of Presentation
  Cold Spring Harbor, USA
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-20590298
[Presentation] E2A negatively regulates TCR Vγ3 rearrangement via transcriptional repressor, Gfi-1.2010
- Author(s)
  Wakae K, Yamashita M, Nakayama T, Minato N, Agata Y
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  神戸市、日本
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PROJECT-20590298
[Presentation] E2A and CBP/p300 act in synergy to promote chromatin accessibility of the immunoglobulin κ locus in nonlymphoid cells2010
- Author(s)
  Agata Y
- Organizer
  Gene Expression & Signaling in the Immune System
- Place of Presentation
  Cold Spring Harbor, USA
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PUBLICLY-22021021
[Presentation] bHLH転写因子E2AによるVγ2遺伝子再構成の制御機構2010
- Author(s)
  野崎昌俊、柳原格、縣保年
- Organizer
  Kyoto T Cell Conference
- Place of Presentation
  京都市、日本
- Year and Date
  2010-06-04
- Data Source
  KAKENHI-PUBLICLY-22021021
[Presentation] E2A negatively regulates TCR Vγ3 rearrangement viatranscriptional repressor, Gfi-12010
- Author(s)
  Wakae K, Sakamoto S, Yamashita M, Nakayama T, Minato N, Agata Y
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  神戸市、日本
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PUBLICLY-22021021
[Presentation] E2A and CBP/p300 act in synergy to promote chromatin accessibility of the immunoglobulin κ locus in nonlymphoid cells.2010
- Author(s)
  Agata Y
- Organizer
  Gene Expression & Signaling in the Immune System
- Place of Presentation
  Cold Spring Harbor, USA
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-20590298
[Presentation] Regulation of Vγ2 gene rearrangement by the helix-loop-helixprotein, E2A.2010
- Author(s)
  Nozaki M, Tamaki N, Sakamoto S, Yanagihara I, Agata Y
- Organizer
  14^<th>International Congress of Immunology
- Place of Presentation
  神戸市、日本
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PROJECT-20590298
[Presentation] Regulation of Vγ2 gene rearrangement by the helix-loop-helix protein, E2A2010
- Author(s)
  Nozaki M, Tamaki N, Sakamoto S, Yanagihara I, Agata Y
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  神戸市、日本
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PUBLICLY-22021021
[Presentation] Regulation of Allelic Exclusion at the TCRβLocus by the Helix-Loop-Helix Protein, E472009
- Author(s)
  縣保年
- Organizer
  Transcriptional Mechanisms of Early Lymphocyte Development
- Place of Presentation
  La Jolla, USA
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-20590298
[Presentation] Regulation of Allelic Exclusion at the TCRβ Locus by the Helix-Loop-Helix Protein, E47.2009
- Author(s)
  Agata Y, Sakamoto S, Tamaki N, Ikawa T, Masuda K, Kawamoto H, Murre C.
- Organizer
  Transcriptional Mechanisms of Early Lymphocyte Development.
- Place of Presentation
  La Jolla, USA
- Data Source
  KAKENHI-PROJECT-20060040
[Presentation] Regulation of Allelic Exclusion at the TCRβ Locus by the Helix-Loop-Helix Protein, E47.2009
- Author(s)
  Agata Y, Sakamoto S, Tamaki N, Ikawa T, Masuda K, Kawamoto H, Murre C.
- Organizer
  Transcriptional Mechanisms of Early Lymphocyte Development.
- Place of Presentation
  La Jolla, USA
- Data Source
  KAKENHI-PROJECT-20590298
[Presentation] Regulation of Allelic Exclusion at the TCRβLocus by the Helix-Loop-Helix Protein, E472008
- Author(s)
  縣保年
- Organizer
  Gene Expression & Signaling in the Immune System
- Place of Presentation
  Cold Spring Harbor, USA
- Year and Date
  2008-04-02
- Data Source
  KAKENHI-PROJECT-20590298
[Presentation] 発生段階特異的なTCRγ遺伝子再構成における転写抑制因子Gfi-1の役割.
- Author(s)
  若江亨祥、坂本修士、山下政克、中山俊憲、湊　長博、縣　保年
- Organizer
  第19回 Kyoto T Cell Conference
- Place of Presentation
  京都
- Data Source
  KAKENHI-PUBLICLY-23118515
[Presentation] コヒーシン/CTCFとE2AによるT細胞初期分化の制御
- Author(s)
  安齋悠樹、山下政克、伊川友活、増田喬子、河本　宏、湊　長博、縣　保年
- Organizer
  Kyoto T Cell Conference
- Place of Presentation
  京都平安ホテル
- Year and Date
  2014-05-16 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-26670136
[Presentation] コヒーシン/CTCFとE2AによるT細胞初期分化の制御
- Author(s)
  安齋悠樹、山下政克、伊川友活、増田喬子、河本　宏、湊　長博、縣　保年
- Organizer
  第24回 Kyoto T Cell Conference
- Place of Presentation
  京都平安ホテル
- Year and Date
  2014-05-16 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-23390068

1. IKAWA Tomokatsu (60450392)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. SATOH Fumiaki (20467426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. TANAKA HIROYUKI (10293820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. WAGATSUMA KEISUKE (10725071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. SHIMIZU Akira (00162694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SAKAMOTO Shuji (80397546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ANZAI YUKI

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. STORB Ursula Beate

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Kawamoto Hiroshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. MARTIN Teren

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MARTIN Terence Edwin

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TERADA Koji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 小林一也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 黒崎知博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 里岡大樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 湊長博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 川上英良

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

agata yasutosi 縣 保年

AGATA Yasutoshi 縣 保年

Research Projects

Research Products

Co-Researchers

Development of cancer immunotherapy using T cells regenerated from iPS cells and cynomolgus macaque cancer modelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of cancer immunotherapy using T cells regenerated from iPS cells and genetically modified cynomolgus macaquePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of cancer immunotherapy using T cells regenerated from iPS cells and genetically engineered monkeysPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Efficient regeneration of tumor-specific cytotoxic lymphocytes using the iPSC technology and genome editingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Purification of the functional transcription factor complex and analyses of the factors that constitute the complexPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

コヒーシンによる染色体構造変化を介した造血細胞分化の制御機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel epigenetic regulation of the gene expression program by chromosome dynamicsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

抗原受容体遺伝子の対立遺伝子排除による自己形成の分子基盤Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

TCR遺伝子の対立遺伝子排除による自己形成の分子基盤Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulatory mechanisms of allelic exclusion by epigenetics and chromosome dynamicsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the epigenetic regulation of the antigen receptor gene rearrangementPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

体細胞突然変異の遺伝子部位特異的な導入機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Znフィンガー因子の系統的遺伝子単離と転写調節における機能の解析Principal Investigator

Principal Investigator

Project Period (FY)

agata yasutosi 縣保年

AGATA Yasutoshi 縣保年

[Book] 標準免疫学第4版2021