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MIYAZAKI Yoichi  宮崎 陽一

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… Alternative Names

宮崎 陽一  ミヤザキ ヨウイチ

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Researcher Number 60266690
Other IDs
Affiliation (Current) 2025: 東京慈恵会医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2016 – 2017: 東京慈恵会医科大学, 医学部, 教授
2013 – 2015: 東京慈恵会医科大学, 医学部, 准教授
2007 – 2012: Jikei University School of Medicine, 医学部, 講師
2000 – 2006: 東京慈恵会医科大学, 医学部, 助手
1998: Jikei University School of Medicine Department of Medicine II,Instructor, 内科学講座・第2, 助手
1998: 東京慈恵会医科大学, 内科学講座第2, 助手
1995 – 1996: 東京慈恵会医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Kidney internal medicine / Kidney internal medicine
Except Principal Investigator
Kidney internal medicine / Kidney internal medicine
Keywords
Principal Investigator
noggin / mutants / nephrin / Bmp / glomerulus / mesangium / Glomerulus / mutans / BMP / podocyte … More / Noggin / VEGF / 糸球体内皮細胞 / mesanngium / nephrotoxic serim / BmP / nephrotoxic serum / BMP / 糸球体尿細管連関 / ボーマン嚢上皮細胞 / 糸球体上皮細胞 / Diabetic nephropathy / MMP / 細胞間クロストーク / ネフロン / nephron / cross-talk / proximal tubule / 培養糸球体内皮細胞 / 胎児大動脈三次元器官培 / vegf / 血管係蹄の嵌入性分割 / 遺伝子改変マウス / Tet-on system / レニン-アンギオテンシン系 / 伸展刺激 … More
Except Principal Investigator
Foxc1 / 糸球体硬化 / CAKUT / BMP4 / 転写因子 / Foxc2 / ポドサイト / 腎発生 / ポドサイト傷害 / 尿タンパク / フォークヘッド転写因子 / フォークヘッド / mouse / renal hypoplasia / development / urinary tract / kidney / マウス / 腎低形成 / 発生 / 尿路 / 腎 / brady kinin / cyclic GMP / vascular endothelial cell / endothelial NOS / nitric oxide / mecharical strain / static stretch / glomerular endothelial cell / M-CSF / ICAM-1 / 細胞外基質 / メサンギウム細胞 / マクロファージ / MCP-1 / ブラジキニン / cGMP / 血管内皮細胞 / ecNOS / NO / 機械的ストレス / 伸展刺激 / 糸球体内皮細胞 / 分化 / 糸球体傷害 / 腎尿路形成異常 / 腎臓学 Less
  • Research Projects

    (11 results)
  • Research Products

    (34 results)
  • Co-Researchers

    (8 People)
  •  a trial for generation of parietal podocytesPrincipal Investigator

    • Principal Investigator
      Miyazaki Yoichi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Jikei University School of Medicine
  •  Foxc1/2 transcription factors and glomerulosclerosis

    • Principal Investigator
      MOTOJIMA Masaru
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tokai University
  •  A role of BMP on the development of glomerular capillary tuftsPrincipal Investigator

    • Principal Investigator
      MIYAZAKI Yoichi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Jikei University School of Medicine
  •  Roles of Foxc transcription factors in podocyte injury.

    • Principal Investigator
      MOTOJIMA Masaru
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tokai University
  •  Role of BMP4 on the development of glomerular capillary tufts and the growth of proximal tubulesPrincipal Investigator

    • Principal Investigator
      MIYAZAKII Yoichi (MIYAZAKI Yoichi)
    • Project Period (FY)
      2007 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Jikei University School of Medicine
  •  Role of BMP on the glomerular development and glomerular injuryPrincipal Investigator

    • Principal Investigator
      MIYAZAKI Yoichi
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Jikei University School of Medicine
  •  Role of Bone Morphogenetic Protein on the development of the GlomerulusPrincipal Investigator

    • Principal Investigator
      MIYAZAKI Yoichi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Jikei University School of Medicine
  •  Development of congenital anomalies of the kidney and urinary tract (CAKUT)

    • Principal Investigator
      ICHIKAWA Iekuni
    • Project Period (FY)
      2000 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tokai University
  •  A study on the effect of static stretch on the expression of NOS in glomerular endothelial cells

    • Principal Investigator
      KAWAMURA Tetsuya
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Jikei University School of Medicine
  •  糸球体内皮細胞に対する伸展刺激による局所レニン-アンギオテンシン系の活性化機構(NO系との関連性からの検討)Principal Investigator

    • Principal Investigator
      宮崎 陽一
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Jikei University School of Medicine
  •  糸球体内皮細胞の伸展がメサンギウム細胞機能に及ぼす影響Principal Investigator

    • Principal Investigator
      宮崎 陽一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Jikei University School of Medicine

All 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 1998 Other

All Journal Article Presentation Book

  • [Book] 腎と透析(CAKUTの分子メカニズム)2010

    • Author(s)
      宮崎陽一
    • Total Pages
      68
    • Publisher
      東京医学社
    • Data Source
      KAKENHI-PROJECT-19590964
  • [Book] 腎と透析(尿路発生異常とレニン・アンジオテンシン系)2008

    • Author(s)
      宮崎陽一
    • Total Pages
      64
    • Publisher
      東京医学社
    • Data Source
      KAKENHI-PROJECT-19590964
  • [Journal Article] Unilateral ureteral obstruction attenuates intrarenal angiotensin Ⅱgeneration induced by podocyte injury.2015

    • Author(s)
      Okabe M,Miyazaki Y,Niimura F,Pastan I,Nishiyama A,Yokoo T,Ichikawa I,Matsusaka T.
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: 308・8 Issue: 8 Pages: F932-F937

    • DOI

      10.1152/ajprenal.00444.2014

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-22249033, KAKENHI-PROJECT-23249047, KAKENHI-PROJECT-26461241
  • [Journal Article] Keap1 inhibition attenuates glomerulosclerosis.2014

    • Author(s)
      Miyazaki Y, Shimizu A, Pastan I, Taguchi K, Naganuma E, Suzuki T, Hosoya T, Yokoo T, Saito A, Miyata T, Yamamoto M, Matsusaka T.
    • Journal Title

      Nephrol Dial Transplant

      Volume: 29 Issue: 4 Pages: 783-791

    • DOI

      10.1093/ndt/gfu002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23591202, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25112502, KAKENHI-PUBLICLY-25117703, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-26461241
  • [Journal Article] Mice are unable to endogenously regenerate podocytes during the repair of immunotoxin-induced glomerular injury2014

    • Author(s)
      Miyazaki Y, Shimizu A, Ichikawa I, Hosoya T, Pastan I, Matsusaka T
    • Journal Title

      Nephrol Dial Transplant

      Volume: 29 Pages: 1005-1012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591202
  • [Journal Article] Mice are unable to endogenously regenerate podocytes during the repair of immunotoxin-induced glomerular injury.2014

    • Author(s)
      Miyazaki Y, Shimizu A, Ichikawa I, Hosoya T, Pastan I, Matsusaka T.
    • Journal Title

      Nephrol Dial Transplant

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591202
  • [Journal Article] Keap1 inhibition attenuates glomerulosclerosis2014

    • Author(s)
      Miyazaki Y, Shimizu A, Pastan I, Taguchi K, Naganuma E, Yokoo T, Saito A, Miyata T, Yamamoto M, Matsusaka T
    • Journal Title

      Nephrol Dial Transplant

      Volume: 29 Pages: 783-791

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591202
  • [Journal Article] Foxc1 gene null mutation causes ectopic budding and kidney hypoplasia but not dysplasia.2013

    • Author(s)
      Komaki F,Miyazaki Y, Niimura F,Mtsusaka T, Ichikawa I,Motojima M .
    • Journal Title

      Cells Tissues Organs.

      Volume: 198・1 Issue: 1 Pages: 22-27

    • DOI

      10.1159/000351291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249033, KAKENHI-PROJECT-23249047, KAKENHI-PROJECT-23591202, KAKENHI-PROJECT-25461234
  • [Journal Article] Foxc1 gene null mutation causes ectopic budding and kidney hypoplasia but not dysplasia2013

    • Author(s)
      Komaki F, Miyazaki Y, Niimura F, Matsusaka T, Ichikawa I, Motojima M
    • Journal Title

      Cells Tissues Organs

      Volume: 198 Pages: 22-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591202
  • [Journal Article] ARB protects podocytes from HIV-1 nephropathy independently of podocyte AT12012

    • Author(s)
      Shimizu A,Zhong J, Miyazaki Y Hosoya T, Ichikawa I, Matsusaka T
    • Journal Title

      Nephrol Dial Transplant

      Volume: 27 Pages: 3169-3175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591202
  • [Journal Article] ARB protects podocytes from HIV-1 nephropathy independently of podocyte AT12012

    • Author(s)
      Shimizu A, Zhong J, Miyazaki Y, Hosoya T, Ichikawa I, Matsusaka T.
    • Journal Title

      Nephrol Dial Transplant.

      Volume: 27 Pages: 3169-75

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591202
  • [Journal Article] Sodium-sensitive variability of the antiproteinuric efficacy of RAS inhibitors in outpatients with IgA nephropathy.2009

    • Author(s)
      T.Suzuki, Y Miyazaki, A Shimizu, et al.
    • Journal Title

      Clin Nephrol 72

      Pages: 274-285

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590964
  • [Journal Article] Sodium-sensitive variability of the antiproteinuric efficacy of RAS inhibitors in outpatients with IgA nephropathy2009

    • Author(s)
      Suzuki T, Miyazaki Y, Shimizu A, Ito Y, Okonogi H, Ogura M, Utunomiya Y, Kawamura T, Hosoya T.
    • Journal Title

      Clin Nephrol 72

      Pages: 274-285

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590964
  • [Journal Article] Bmp in podosyte is essential for normal glomerular capillary formatio.2008

    • Author(s)
      Ueda H, Miyazaki Y, Matsusaka T, et. al.
    • Journal Title

      Journal of American Society of Nephrology (in press)

    • Data Source
      KAKENHI-PROJECT-19590964
  • [Journal Article] Bmp in podosyte is essential for normal glomerular capillary formatio.2008

    • Author(s)
      Ueda H, Miyazaki Y, Matsusaka T, et al.
    • Journal Title

      Journal of American Society of Nephrology 19

      Pages: 685-694

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590964
  • [Journal Article] Bmp in podocytes is essential for normal glomerular capillary formation.2008

    • Author(s)
      Ueda H, Miyazaki Y, Matsusaka T, Utsunomiya Y, Kawamura T, Hosoya T, Ichikawa I
    • Journal Title

      J Am Soc Nephrol 19

      Pages: 685-694

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590964
  • [Journal Article] Bmp in podocytes is essential for normal capillary formation2008

    • Author(s)
      Ueda H, Miyazaki Y, Matsusaka T, Utsunomiya Y, Kawamura T, Hosoya T, Ichikawa I
    • Journal Title

      J Am Soc Nephrol 19

      Pages: 685-694

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590964
  • [Journal Article] Bmp4 in podocytes is essential for normal glomerular capillary formation.2007

    • Author(s)
      Ueda H, Miyazaki Y, Matsusaka T, Utsunomiya Y, et al.
    • Journal Title

      J Am Soc Nephrol (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590802
  • [Journal Article] Bmp4 in podocytes is essential for normal glomerular canillary formation2007

    • Author(s)
      Ueda H, Miyazaki Y, Matsusaka T, Utsunomiya Y, Kawamura T, et al.
    • Journal Title

      J Am Soc Nephrol in press

    • Data Source
      KAKENHI-PROJECT-16590802
  • [Journal Article] Bmp4 in podocytes is essential for normal glomerular capillary formation.2007

    • Author(s)
      Ueda H, Miyazaki Y, Matsusaka T, Utsunomiya Y, Kawamura T, Ichikawa I.
    • Journal Title

      J Am Soc Nephrol (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590802
  • [Journal Article] Xenobiotic kidney organogenesis from human mesenchymal stem cells using a growing rodent embryo.2006

    • Author(s)
      Yokoo T, Fukui A, Ohashi T, Miyazaki Y, Utsunomiya Y, Kawamura T, Hosoya T, Okabe M, Kobayashi E.
    • Journal Title

      J Am Soc Nephrol 17

      Pages: 1026-1034

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590802
  • [Journal Article] Xenobiotic kidney organogenesis from human mesenchymal stem cells using a growing rodent embryo.2006

    • Author(s)
      Yokoo T, Fukui A, Ohashi T, Miyazaki Y, Utsunomiya Y, et al.
    • Journal Title

      J Am Soc Nephrol 17

      Pages: 1026-1034

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590802
  • [Journal Article] Inhibition of endogenous BMP in the glomerulus leads to mesangial matrix Expansion.2006

    • Author(s)
      Miyazaki Y, Ueda H, Yokoo T, Utsunomiya Y, Kawamura T, et al.
    • Journal Title

      Biochem Biophys Res Commun 340

      Pages: 681-688

    • Data Source
      KAKENHI-PROJECT-16590802
  • [Journal Article] Inhibition of endogenous BMP in the glomerulus leads to mesangial matrix Expansion.2006

    • Author(s)
      Miyazaki Y, Ueda H, Yokoo T, Utsunomiya Y, Kawamura T, Matsusaka T, Ichikawa I, Hosoya T.
    • Journal Title

      Biochem Biophys Res Commun 340

      Pages: 681-688

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590802
  • [Journal Article] Inhibition of endogenous BMP in the glomerulus leads to mesangial matrix Expansion.2006

    • Author(s)
      Miyazaki Y, Ueda H, Yokoo T, Utsunomiya Y, et al.
    • Journal Title

      Biochem Biophys Res Commun 340

      Pages: 681-688

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590802
  • [Journal Article] Human mesenchymal stem cells in rodent whole-embryo culture are reprogrammed to contribute to kidney tissues2005

    • Author(s)
      Yokoo Y, Ohashi T, Shen JS, Sakurai K, Miyazaki Y, et al.
    • Journal Title

      Proc Natl Acad Sci USA 102

      Pages: 3296-3300

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590802
  • [Journal Article] Human mesenchymal stem cells in rodent whole-embryo culture are reprogrammed to contribute to kidney tissues2005

    • Author(s)
      Yokoo Y, Ohashi T, Shen JS, Sakurai K, Miyazaki Y, Utsunomiya Y, Takahashi M, Terada Y, Eto Y, Kawamura T, Osumi N, Hosoya T.
    • Journal Title

      Proc Natl Acad Sci USA 102

      Pages: 3296-3300

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590802
  • [Journal Article] Foxc1 gene null mutation causes ectopic budding and kidney hypoplasia, but not dysplasia

    • Author(s)
      Komaki, F.; Miyazaki, Y.; Niimura, F.; Matsusaka, T.; Ichikawa, I.; Motojima, M.
    • Journal Title

      CELLS TISSUES ORGANS

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590899
  • [Presentation] Keap1-Nrf2経路と糖尿病性腎症2012

    • Author(s)
      清水昭博、松阪泰二、宮崎陽一、細谷龍男、宮田敏男、山本雅之
    • Organizer
      日本腎臓学会学術総会(シンポジウム)
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23591202
  • [Presentation] Podocyte-Derived VEGF Regulates Glomerular Tuft Development via the Suppression of PDGF ReceptorβPhosphorylation of the Smooth Muscle2012

    • Author(s)
      Suyama M, Miyazaki Y, Utsunomiya Y, Kawamura T, Matsusaka T, Ichikawa I, Hosoya T
    • Organizer
      Annual Meeting of American Society of Nephrology
    • Place of Presentation
      San Diego, CA
    • Data Source
      KAKENHI-PROJECT-23591202
  • [Presentation] Ectopic ureteral budding from the wolffian duct results in hypoplastic, but not dysplastic, kidney2011

    • Author(s)
      発表者:本島 英、小牧文代、宮崎陽一、新村文男、松阪泰二 、市川家國
    • Organizer
      米国腎臓学会年会
    • Place of Presentation
      フィラデルフィア
    • Year and Date
      2011-11-10
    • Data Source
      KAKENHI-PROJECT-22590899
  • [Presentation] 糸球体血管係蹄の発生と再生(ワークショップ)1998

    • Author(s)
      宮崎陽一
    • Organizer
      第51回日本腎臓学会
    • Place of Presentation
      福岡
    • Year and Date
      1998-05-31
    • Data Source
      KAKENHI-PROJECT-19590964
  • [Presentation] Podocyte-Derived VEGF Regulates Glomerular Tuft Development through the

    • Author(s)
      Suyama M, Miyazaki Y, Utsunomiya Y, Kawamura T, Matsusaka T, Ichikawa I, Hosoya T
    • Organizer
      45th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      San Diego, CA, USA
    • Data Source
      KAKENHI-PROJECT-23591202
  • [Presentation] 糸球体血管係蹄発生と再生

    • Author(s)
      宮崎陽一, 上田裕之, 松阪泰二, 市川家國
    • Organizer
      日本腎臓学会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-19590964
  • 1.  MATSUSAKA Taiji (50317749)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 3 results
  • 2.  ICHIKAWA Iekuni (80317768)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 3.  MOTOJIMA Masaru (80468636)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 4.  KAWAMURA Tetsuya (20161367)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  OHTSUKA Masato (90372945)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  新村 文男
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 7.  西山 成
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  PASTAN Ira
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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