KAWASAKI Kiyoshi 川崎清史

… Alternative Names

KAWASAKI Kiyosi 川崎清史

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Researcher Number	60270641
Other IDs
External Links
Affiliation (Current)	2025: 同志社女子大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2010 – 2023: Doshisha Women's College of Liberal Arts, 薬学部, 教授 2006 – 2010: 同志社女子大学, 薬学部, 准教授 2006: 同志社女子大学, 薬学部, 助教授 2004 – 2005: 国立感染症研究所, 細胞化学部, 室長 2000 – 2002: 国立感染症研究所, 細胞化学部, 主任研究官 1997 – 1999: NIID,Researcher, 細胞化学部, 研究員 1995 – 1996: 国立予防衛生研究所, 細胞化学部, 研究員
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological pharmacy / Environmental and hygienic pharmacy / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Environmental pharmacy Except Principal Investigator Biological pharmacy / Biological Sciences / Biological pharmacy
Keywords	Principal Investigator エンドトキシン / リポ多糖 / 自然免疫 / 脱アシル化 / 外膜 / Toll-like receptor / deacylation / lipid A / endotoxin / lipopolysaccharide … More / 免疫刺激 / 脂質 / 活性調節 / 細菌 / ホスファチジルグリセロール / カルジオリピン / リン脂質 / ミトコンドリア / DNA / 応答性調節 / ペプチド / 生体分子 / 感染症 / 薬学 / Ｄ－アミノ酸 / 免疫 / 内毒素 / 抗菌ペプチド / マクロファージ / point-mutation / regulation / enzyme / lipase / Salmonella enterica / アラニン置換 / アミノアラビノース修飾 / 活性抑制 / サルモネラ菌 / 点変異体 / 酵素 / リパーゼ / リボ多糖 / サルモネラ / Gram-negative bacteria / アミノアラビノース付加 / エタノールアミン / リピドA / グラム陰性菌 / 菌体成分 / 質量分析 / 認識 / リモデリング / 宿主認識 / シグナル伝達 / 膜透過性 / 潜伏化 / 遺伝子生化学 / MD-2 / タキソール / ホスファチジルグリセロール / CHO細胞 / ホスファチジン酸 / ホスホリパーゼD … More Except Principal Investigator LPS / MD-2 / タキソール / TLR4 / Toll-like receptor / sphingolipid / ホスファチジルセリン / LCB1 / スフィンゴ脂質 / アラニンスキャン法 / CD14 / マクロファージ / Flavolipin / Taxol / khafrefungin / phospholipids / Baculovirus / ホスホリパーゼC / 熱帯熱マラリア原虫 / コレステロール / スフィンゴミエリン / lipid raft / シンドビスウィルス / アミノ含有脂質 / カフレファギン / 抗真菌剤 / フラボリピン / カフレファンギン / リン脂質 / バキュロウイルス / phosphatidylcholine / phospholipase D / cardiolipin / phosphatidylserine / CHO cell / NK-κB / ホスァチジルセリン / NF-κB / ホスファチジルグリセロールリン酸 / RhoA / ホスフォリパーゼD / LCB2 / SPT(セリンパルミトイルトランスフェラーゼ) / ホスファチジルコリン / ホスフォリバーゼD / カルジオリピン / ホスファチジルグリセリン / CHO細胞 / ペプチドグリカン / 感染 / リポ多糖 / 細胞内寄生細菌 / エキソソーム / 細胞内増殖 / 質量分析 / エンドトキシン / 細菌 / 脂質 / TNF-α Less

自然免疫の応答性を調節する抗菌ペプチド等に関する研究Principal Investigator
- Principal Investigator
  
  川崎清史
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Doshisha Women's College of Liberal Arts
Infectious disease drug discovery research using substances that attack and defend between organisms such as endotoxins and antimicrobial peptidesPrincipal Investigator
- Principal Investigator
  
  Kawasaki Kiyoshi
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  Doshisha Women's College of Liberal Arts
Creation of a low toxic derivative biosynthesis system for biologically active substances derived from bacteria such as endotoxinPrincipal Investigator
- Principal Investigator
  
  Kawasaki Kiyoshi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  Doshisha Women's College of Liberal Arts
Lipopolysaccharide remodeling in bacterial adaptation to hostPrincipal Investigator
- Principal Investigator
  
  KAWASAKI Kiyoshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Doshisha Women's College of Liberal Arts
Research for host-recognition and responses against endotoxin modified by pathogenic bacteria.Principal Investigator
- Principal Investigator
  
  KAWASAKI Kiyoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Doshisha Women's College of Liberal Arts
Study on the formation and function of exosomes
- Principal Investigator
  
  NISHIJIMA Masahiro
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Institute of Health Sciences
Research for outer membrane remodeling in Salmonella entericaPrincipal Investigator
- Principal Investigator
  
  KAWASAKI Kiyoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Doshisha Women's College of Liberal Arts
Study for the factor involved in endotoxin ercognitionPrincipal Investigator
- Principal Investigator
  
  KAWASAKI Kiyoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Insititute of Infectious Diseases
マクロファージによる異物認識の分子的基盤に関する研究
- Principal Investigator
  
  西島正弘
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Infectious Diseases
マクロファージによる異物認識の分子的基盤に関する研究
- Principal Investigator
  
  NISHIJIMA Masahiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Infectious Diseases
ニワトリ細胞株を利用したミトコンドリアリン脂質の細胞機能に関する遺伝生化学的研究Principal Investigator
- Principal Investigator
  
  川崎清史
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Institute of Infectious Diseases
The role of host cell membrane lipids in infection of microorganisms and in host defense mechanisms
- Principal Investigator
  
  NISHIJIMA Masahiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Institute of Infectious Diseases
CD14欠損変異株を利用したリポ多糖によるマクロファージ活性化機構の研究Principal Investigator
- Principal Investigator
  
  川崎清史
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Environmental pharmacy
- Research Institution
  National Institute of Infectious Diseases
ミトコンドリアに特徴的なリン脂質の生合成と機能の遺伝生化学的研究Principal Investigator
- Principal Investigator
  
  川崎清史
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Institute of Infectious Diseases
動物細胞における膜リン脂質変換酵素ホスホリパーゼDの機能解析Principal Investigator
- Principal Investigator
  
  川崎清史
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  国立予防衛生研究所
genetic and biochemical study on intracellular lipid transport and lipid functions in microdomain
- Principal Investigator
  
  NISHIJIMA Masahiro
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Institute of Infectious Diseases

[Journal Article] 非メチル化CpGDNAに対する自然免疫応答を増強するαーヘリックス型抗菌ペプチド2023
- Author(s)
  西原冴佳　川崎清史
- Journal Title
  
  細胞
  
  Volume: 55 Pages: 699-703
- Data Source
  KAKENHI-PROJECT-22K06607
[Journal Article] Relationship Between Affinity of Kn2-7 to CpG DNA and the Ability of Kn2-7 to Enhance Cellular Uptake of CpG DNA by RAW264.7 Cells2021
- Author(s)
  Nishihara Saeka、Wakita Mayu、Kawasaki Kiyoshi
- Journal Title
  
  BPB Reports
  
  Volume: 4 Issue: 2 Pages: 55-58
- DOI
  10.1248/bpbreports.4.2_55
- NAID
  130008000222
- ISSN
  2434-432X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08397
[Journal Article] Phagocytosis of microparticles increases responsiveness of macrophage-like cell lines U937 and THP-1 to bacterial lipopolysaccharide and lipopeptide2021
- Author(s)
  Ueno Takayuki、Yamamoto Yumi、Kawasaki Kiyoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 1-15
- DOI
  10.1038/s41598-021-86202-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08397
[Journal Article] Enhanced cellular uptake of CpG DNA by α-helical antimicrobial peptide Kn2-7: Effects on macrophage responsiveness to CpG DNA2020
- Author(s)
  Nishihara Saeka、Kawasaki Kiyoshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 530 Issue: 1 Pages: 100-106
- DOI
  10.1016/j.bbrc.2020.07.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08397
[Journal Article] Imidazolines increase the levels of the autophagosomal marker LC3-II in macrophage-like RAW264.7 cells2018
- Author(s)
  Shiori Nakagawa, Takayuki Ueno, Takayuki Manabe, and Kiyoshi Kawasaki
- Journal Title
  
  Can. J. Physiol. Pharmacol.
  
  Volume: 印刷中 Issue: 8 Pages: 845-849
- DOI
  10.1139/cjpp-2018-0021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08397, KAKENHI-PROJECT-26460179
[Journal Article] D-form KLKLLLLLKLK-NH2 peptide exerts higher antimicrobial properties than its L-form counterpart via an association with bacterial cell wall components2017
- Author(s)
  Takayuki Manabe and Kiyoshi Kawasaki
- Journal Title
  
  Scientific reports
  
  Volume: 7 Issue: 1 Pages: 43384-43384
- DOI
  10.1038/srep43384
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460179
[Journal Article] Flagella proteins contribute to the production of outer membrane vesicles from Escherichia coli W31102013
- Author(s)
  Takayuki Manabe, Mayu Kato, Takayuki Ueno, and Kiyoshi Kawasaki
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: vol.441 Issue: 1 Pages: 151-156
- DOI
  10.1016/j.bbrc.2013.10.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590095
[Journal Article] 3'-O-deacylation by Salmonella outer membrane enzyme LpxR modulates the ability of lipid A to stimulate Toll-like receptor 42012
- Author(s)
  Kiyoshi Kawasaki, Mai Teramoto, Rie Tatsui, Shoko Amamoto
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 428 Issue: 3 Pages: 343-347
- DOI
  10.1016/j.bbrc.2012.10.054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590095
[Journal Article] Latency of the lipid A deacylase PagL is involved in producing a robust permeation barrier in the outer membrane of Salmonella enterica2010
- Author(s)
  Kawasaki K., 他1名
- Journal Title
  
  J. Bacteriol.
  
  Volume: 192 Pages: 5837-5840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590073
[Journal Article] 自然免疫の鍵を握るToll-like receptor2010
- Author(s)
  川崎清史
- Journal Title
  
  ファルマシア vol.46
  
  Pages: 2-7
- NAID
  110009867572
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390032
[Journal Article] Salmonella enterica serovar Typhimurium lipopolysaccharide deacylation enhances its intracellular growth within macrophages2010
- Author(s)
  Miyuki Kawano, Takayuki Manabe, Kiyoshi Kawasaki
- Journal Title
  
  FEBS lett. vol.584
  
  Pages: 207-212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590073
[Journal Article] Salmonella enterica serovar Typhimurium lipopolysaccharide deacylation enhances its intracellular growth within macrophages.2010
- Author(s)
  Miyuki Kawano, Takayuki Manabe, Kiyoshi Kawasaki
- Journal Title
  
  FEBS lett. vol.584
  
  Pages: 207-212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390032
[Journal Article] Mutations in the lipid A deacylase PagL which release the enzyme from its latency affect the ability of PagL to interact with lipopolysaccharide in Salmonella enterica serovar Typhimurium.2010
- Author(s)
  Takayuki Manabe, Miyuki Kawano, Kiyoshi Kawasaki
- Journal Title
  
  Biochem.Biophys.Res.Commun. vol.396
  
  Pages: 812-816
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590073
[Journal Article] Latency of the lipid A deacylase PagL is involved in producing a robust permeation barrier in the outer membrane of Salmonella enterica2010
- Author(s)
  Kawasaki K., 他1名
- Journal Title
  
  J.Bacteriol.
  
  Volume: 192 Pages: 5837-5840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590073
[Journal Article] 自然免疫の鍵を握る Toll-like receptor2010
- Author(s)
  川崎清史
- Journal Title
  
  ファルマシア 46
  
  Pages: 2-7
- NAID
  110009867572
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390032
[Journal Article] Latency of the lipid A deacylase PagL is involved in producing a robust permeation barrier in the outer membrane of Salmonella enterica.2010
- Author(s)
  Kiyoshi Kawasaki, Takayuki Manabe
- Journal Title
  
  J.Bacteriol. vol.192
  
  Pages: 5837-5840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590073
[Journal Article] Alternative procedures for analysis of lipid A modification with phosphoethanolamine or aminoarabinose2009
- Author(s)
  Kiyoshi Kawasaki
- Journal Title
  
  J.Microbiol.Methods vol.76
  
  Pages: 313-315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590073
[Journal Article] サルモネラのリポ多糖脱アシル化と抗菌ペプチド抵抗性2009
- Author(s)
  川崎清史
- Journal Title
  
  エンドトキシン研究 11
  
  Pages: 26-28
- Data Source
  KAKENHI-PROJECT-18390032
[Journal Article] サルモネラのリポ多糖脱アシル化と抗菌ペプチド抵抗性2009
- Author(s)
  川崎清史
- Journal Title
  
  エンドトキシン研究 vol.11
  
  Pages: 26-28
- Data Source
  KAKENHI-PROJECT-18390032
[Journal Article] Alternative procedures for analysis of lipid A modification with phosphoethanolamine or aminoarabinose2009
- Author(s)
  Kiyoshi Kawasaki
- Journal Title
  
  J. Microbiol. Methods 6
  
  Pages: 313-315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590073
[Journal Article] The preparation of a lipidic endotoxin affects its biological activities.2008
- Author(s)
  K. Okemoto, K. Hanada, M. Nishijima, K. Kawasaki
- Journal Title
  
  Biol. Pharm. Bull. vol.31
  
  Pages: 1952-1954
- NAID
  110006936340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390032
[Journal Article] Extracellular loops of lipid A 3-O-deacylase PagL are involved in recognition of aminoarabinose-based membrane modifications in Salmonella enterica serovar Typhimurium.2008
- Author(s)
  T. Manabe, K. Kawasaki
- Journal Title
  
  J.Bacteriol. vol.190
  
  Pages: 5597-5606
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590073
[Journal Article] The preparation of a lipidic endotoxin affects its biological activities2008
- Author(s)
  Kazuo Okemoto, Kentaro Hanada, Masahiro Nishijima, Kiyoshi Kawasaki
- Journal Title
  
  Biol.Pharm.Bull. vol.31
  
  Pages: 1952-1954
- NAID
  110006936340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590073
[Journal Article] The preparation of a lipidic endotoxin affects its biological activities2008
- Author(s)
  K. Okemoto, K. Hanada, M. Nishijima, and K. Kawasaki
- Journal Title
  
  Biol. Pharm. Bull vol.31
  
  Pages: 1952-1954
- NAID
  110006936340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390032
[Journal Article] Release of lipopolysaccharide deacylase PagL from latency compensates for a lack of lipopolysaccharide aminoarabinose modification-dependent resistance to antimicrobial peptide polymyxin B in Salmonella enterica.2007
- Author(s)
  K. Kawasaki, K. China, M. Nishijima.
- Journal Title
  
  J. Bacteriol. vol.189
  
  Pages: 4911-4919
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390032
[Journal Article] Release of lipopolysaccharide deacylase PagL from latency compensates for a lack of lipopolysaccharide aminoarabinose modification-dependent resistance to antimicrobial peptide polymyxin B in Salmonella enterica2007
- Author(s)
  K.Kawasaki, 他2名
- Journal Title
  
  J.Bacteriol. 189
  
  Pages: 4911-4919
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590091
[Journal Article] Release of lipopolysaccharide deacylase PagL from latency compensates for a lack of lipopolysaccharide aminoarabinose modification-dependent resistance to antimicrobial peptide polymyxin B in Salmonella enterica.2007
- Author(s)
  K. Kawasaki, et. al.
- Journal Title
  
  J. Bacteria 189
  
  Pages: 4911-4919
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590091
[Journal Article] Release of lipopolysaccharide deacylase PagL from latency compensates for a lack of lipopolysaccharide aminoarabinose modification-dependent resistance to antimicrobial peptide polymyxin B in Salmonella enterica2007
- Author(s)
  K. Kawasaki, K. China, and M. Nishijima, M. Kobayashi, S. Saitoh, N. Tanimura, K. Takahashi
- Journal Title
  
  J. Bacteriol vol. 189
  
  Pages: 4911-4919
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390032
[Journal Article] Release of lipopolysaccharide deacylase PagL from latency compensates for a lack of lipopolysaccharide aminoarabinose modification-dependent resistance to antimicrobial peptide polymyxin B in Salmonella enterica.2007
- Author(s)
  K, Kawasaki, 他2名
- Journal Title
  
  J Bacteriol. 189
  
  Pages: 4911-4919
- Data Source
  KAKENHI-PROJECT-18390032
[Journal Article] Outermembrane remodeling of Salmonella typhimurium and host innate immunity2006
- Author(s)
  K. Kawasaki
- Journal Title
  
  YAKUGAKU ZASSHI 126
  
  Pages: 1227-1234
- NAID
  110004997526
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590091
[Journal Article] サルモネラ菌の外膜リモデリングと宿主応答2006
- Author(s)
  川崎清史
- Journal Title
  
  薬学雑誌 126
  
  Pages: 1227-1234
- NAID
  110004997526
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590091
[Journal Article] サルモネラ菌の外膜リモデリングと宿主応答2006
- Author(s)
  川崎清史
- Journal Title
  
  薬学雑誌 Vol.126
  
  Pages: 1227-1234
- NAID
  110004997526
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390032
[Journal Article] サルモネラ菌の外膜リモデリングと宿主応答2006
- Author(s)
  川崎清史
- Journal Title
  
  薬学雑誌 126
  
  Pages: 1227-1234
- NAID
  110004997526
- Data Source
  KAKENHI-PROJECT-18590091
[Journal Article] Regulatory roles for MD-2 and TLR4 in ligand-induced receptor clustering.2006
- Author(s)
  M. Kobayashi, S. Saitoh, N. Tanimura, K. Takahashi, K. Kawasaki, M. Nishijima, Y. Fujimato, K. Fukase, S. Akashi-Takamura, K. Miyake.
- Journal Title
  
  J. Immunol. vol.176
  
  Pages: 6211-6218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390032
[Journal Article] Regulatory roles for MD-2 and TLR4 in ligand-induced receptor clustering2006
- Author(s)
  K. Kawasaki, M. Nishijima, Y. Fujimato, K. Fukase, S. Akashi-Takamura, K. Miyake
- Journal Title
  
  J. Immunol vol.176
  
  Pages: 6211-6218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390032
[Journal Article] サルモネラ菌の外膜リモデリングと宿主応答2006
- Author(s)
  川崎清史
- Journal Title
  
  薬学雑誌 126
  
  Pages: 1227-1234
- NAID
  110004997526
- Data Source
  KAKENHI-PROJECT-18390032
[Journal Article] Inhibition oi Salmonella enterica serovar Typhimurium lipop olysaccharide deacylation by aminoarabinose membrane modi2005
- Author(s)
  K Kawasaki et al.
- Journal Title
  
  J. Bacteriol. 187
  
  Pages: 2448-2457
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590078
[Journal Article] Inhibition of Salmonella enterica serovar Typhimurium lipopolysaccharide deacylation- by aminoarabinose membrane modification.2005
- Author(s)
  K Kawasaki et al.
- Journal Title
  
  J Bacterlol. 187
  
  Pages: 2448-2457
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590078
[Journal Article] Inhibition of Salmonella enterica serovar Typhimurium lipopolysaccharide deacylation by aminoarabinose membrane modification.2005
- Author(s)
  K Kawasaki et al.
- Journal Title
  
  J.Bacteriol. 187(In press)
- Data Source
  KAKENHI-PROJECT-16590078
[Journal Article] Inhibition of Salmonella enterica serovar Typhimurium lipopolysaccha ride deacylation by aminoarabinose membrane modification.2005
- Author(s)
  K Kawasaki et al.
- Journal Title
  
  J.Bacteriol. 187
  
  Pages: 2448-2457
- Data Source
  KAKENHI-PROJECT-16590078
[Presentation] Achromobacter xylosoxidans由来水酸化オルニチン脂質の免疫刺激活性2017
- Author(s)
  安藤美菜子、橋村咲良、川崎清史
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-27
- Data Source
  KAKENHI-PROJECT-26460179
[Presentation] Achromobacter xylosoxidansからの水酸化オルニチン脂質精製2016
- Author(s)
  安藤美菜子、多田絢夏、由岡麻衣香、川崎清史
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-26460179
[Presentation] リポ多糖刺激によるTHP1細胞からのTNFα分泌に異物貪食が協調的に作用する2013
- Author(s)
  上野貴之、川崎清史
- Organizer
  第86回日本生化学会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2013-09-11
- Data Source
  KAKENHI-PROJECT-23590095
[Presentation] 大腸菌W3110株の鞭毛形成は細胞外分泌小胞の分泌を誘導する2013
- Author(s)
  眞鍋貴行、加藤まゆ、川崎清史
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2013-03-30
- Data Source
  KAKENHI-PROJECT-23590095
[Presentation] リポ多糖のリピドA部位のLpxRによる脂肪酸修飾が生物活性に与える影響2013
- Author(s)
  辰井理恵、西川実季、天本翔子、寺本舞、川崎清史
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2013-03-30
- Data Source
  KAKENHI-PROJECT-23590095
[Presentation] ヒトマクロファージ様細胞において貪食がリポ多糖刺激に伴うTNFα産生に及ぼす影響の解析2013
- Author(s)
  上野貴之、川崎清史
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2013-03-30
- Data Source
  KAKENHI-PROJECT-23590095
[Presentation] 大腸菌W3110株のOuter Membrane Vesicle分泌には鞭毛形成が重要である2012
- Author(s)
  眞鍋貴行、加藤まゆ、川崎清史
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡国際会議場他(福岡県)
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-23590095
[Presentation] 大腸菌W3110株の膜小胞形成には鞭毛タンパク質をコードするfliCが重要である2012
- Author(s)
  眞鍋貴行、川崎清史
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-23590095
[Presentation] 細菌外膜酵素によるリポ多糖修飾がその生物活性に与える影響2011
- Author(s)
  寺本舞、天本翔子、川崎清史
- Organizer
  第61回日本薬学会近畿支部会
- Place of Presentation
  神戸学院大学(兵庫県)
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-23590095
[Presentation] CD14欠損のサルモネラ細胞内増殖への影響2011
- Author(s)
  後藤史子、中村映理子、川崎清史
- Organizer
  第61回日本薬学会近畿支部会
- Place of Presentation
  神戸学院大学(兵庫県)
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-23590095
[Presentation] Salmonella enterica serovar Typhimurium lipopolysaccharide deacylation enhances its intracellular growth within macrophages.2010
- Author(s)
  K. Kawasaki, M. Kawano
- Organizer
  Annual meetings of the Society for Leukocyte biology and The international Endotoxin and Innate Immunity Society
- Place of Presentation
  バンクーバー(カナダ)
- Data Source
  KAKENHI-PROJECT-20590073
[Presentation] サルモネラリポ多糖脱アシル化酵素PagLの活性抑制にはリポ多糖との結合が重要である2010
- Author(s)
  眞鍋貴行、河野美幸、川崎清史
- Organizer
  第83回日本生化学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590073
[Presentation] 二成分制御系PhoP-PhoQ活性化によるサルモネラ外膜透過性障壁の強化に外膜脱アシル化酵素の潜伏性が関与する2010
- Author(s)
  川崎清史、眞鍋貴行
- Organizer
  第83回日本生化学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590073
[Presentation] Salmonella enterica serovar Typhimurium lipopolysaccharide deacylation enhances its intracellular growth within macrophages2010
- Author(s)
  Kawasaki K., 他1名
- Organizer
  Annual meetings of the Society for Leukocyte biology and The international Endotoxin and Innate I mmunity Society
- Place of Presentation
  バンクーバー、カナダ
- Data Source
  KAKENHI-PROJECT-20590073
[Presentation] サルモネラ外膜リパーゼ(PagL)の潜伏性に関わるアミノ酸残基の解析2010
- Author(s)
  川崎清史、眞鍋貴行
- Organizer
  第52回日本脂質生化学会
- Place of Presentation
  群馬県渋川市
- Data Source
  KAKENHI-PROJECT-20590073
[Presentation] Salmonella enterica serovar Typhimurium lipopolysaccharide deacylation enhances its intracellular growth within macrophages2010
- Author(s)
  Kawasaki K., 他1名
- Organizer
  Annual meetings of the Society for Leukocyte biology and The international Endotoxin and Innate Immunity Society
- Place of Presentation
  バンクーバー、カナダ
- Year and Date
  2010-09-30
- Data Source
  KAKENHI-PROJECT-20590073
[Presentation] LpxRによるリピドA脱アシル化はサルモネラの効率的な細胞増殖に必要である2009
- Author(s)
  河野美幸、眞鍋貴行、川崎清史
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590073
[Presentation] LpxRによるリピドA脱アシル化はサルモネラの効率的な細胞増殖に必要である2009
- Author(s)
  河野美幸、眞鍋貴行、川崎清史
- Organizer
  日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-18390032
[Presentation] サルモネラLPS脱アシル化酵素PagLの活性調節に関与するアミノ酸残基は他の外膜タンパク質との相互作用に重要である2009
- Author(s)
  眞鍋貴行、河野美幸、川崎清史
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590073
[Presentation] サルモネラLPS脱アシル化酵素PagLの活性調節に関与するアミノ酸残基は他の外膜タンパク質との相互作用に重要である2009
- Author(s)
  眞鍋貴行、河野美幸、川崎清史
- Organizer
  日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-18390032
[Presentation] LPS deacylase recognize membrane axninoarabinose modification in S. enterica.2008
- Author(s)
  T. Manabe, K Kawasaki
- Organizer
  81th meetings of Japan Bacteriology Society
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590091
[Presentation] Extracellular loops of lipid A 3-O-deacylase PagL are involved in recognition of aminoarabinose-based membrane modifications in Salmonella enterica.2008
- Author(s)
  K. Kawasaki, T. Manabe
- Organizer
  10th Biennial Meeting of the International Endotoxin and Innate Immunity Society
- Place of Presentation
  エジンバラ(イギリス)
- Data Source
  KAKENHI-PROJECT-20590073
[Presentation] Exacraoellular loops of lipid A 3-O-deacylase PagL are involved in recognit ionof aminoarabinose-based membrane modifications in Salmonella enterica2008
- Author(s)
  Kiyoshi Kawasaki, 他1名
- Organizer
  10^<th>Biennial Meeting of the International Endotoxin and Innate Immunity Society
- Place of Presentation
  Edinburgh, UK
- Data Source
  KAKENHI-PROJECT-20590073
[Presentation] サルモネラ菌のLPS脱アシル化酵素は外膜のアミノアラビノース修飾を認識する2008
- Author(s)
  眞鍋貴行、川崎清史
- Organizer
  第81回日本細菌学会総会
- Place of Presentation
  京都
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590091
[Presentation] Regulation and functions of lipopolysaccharide modifications in S. enterica2007
- Author(s)
  K. Kawasaki
- Organizer
  19th symposium on Microbiology
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590091
[Presentation] サルモネラ菌の抗菌ペプチド感受性のLPS脱アシル化による調節2007
- Author(s)
  川崎清史、西島正弘
- Organizer
  日本エンドトキシン研究会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-18390032
[Presentation] lps脱アシル化酵素の活性調節に関与するアミノ酸残基の同定2007
- Author(s)
  眞鍋貴行、西島正弘、川崎清史
- Organizer
  第日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390032
[Presentation] サルモネラ菌の抗菌ペプチド感受性のLPS脱アシル化による調節2007
- Author(s)
  川崎清史、西島正弘
- Organizer
  第13回日本エンドトキシン研究会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-18390032
[Presentation] サルモネラ菌のリポ多糖修飾の機能と制御2007
- Author(s)
  川崎清史
- Organizer
  第19回微生物シンポジウム
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590091
[Presentation] サルモネラ菌のリボ多糖修飾の機能と制御2007
- Author(s)
  川崎清史
- Organizer
  第19回微生物シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18590091
[Presentation] サルモネラ菌の抗菌ペプチド感受性のLPS脱アシル化による調節2007
- Author(s)
  川崎清史、西島正弘
- Organizer
  第13回日本エンドトキシン研究会
- Place of Presentation
  鹿児島
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590091
[Presentation] Modulation of susceptibility of antimicrobial peptide in S. typhimurium by lipid A deacylation2007
- Author(s)
  K. Kawasaki, M Nishijima
- Organizer
  13th meetings of Japan Endotoxin Society
- Place of Presentation
  Kagoshima
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590091
[Presentation] Lipopolysaccharide deacylation controls resistance to cationic antimicrobial peptide polymyxin B in Salmonella typhimurium2006
- Author(s)
  Kiyoshi Kawasaki, 他2名
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  京都
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590091
[Presentation] サルモネラ菌抗菌ペプチド感受性のLPS脱アシル化による制御2006
- Author(s)
  川崎清史, 他2名
- Organizer
  第48回日本脂質生化学会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590091
[Presentation] Lipopolysaccharide deacylation controls resistance to cationic antimicrobial peptide polymyxin B in Salmonella typhimurium2006
- Author(s)
  K. Kawasaki, et. al.
- Organizer
  20th IUBMB
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590091
[Presentation] Regulation of susceptibility of antimicrobial peptide in S. typhimurium by lipid A deacylation2006
- Author(s)
  K. Kawasaki, et. al.
- Organizer
  48th JCBL
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590091
[Presentation] リポ多糖のリピドA部位のLpxRによる脂肪酸修飾が生物活性に与える影響
- Author(s)
  辰井理恵、西川実季、天本翔子、寺本舞、川崎清史
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23590095
[Presentation] ヒトマクロファージ様細胞において貪食がリポ多糖刺激に伴うTNFα産生に及ぼす影響の解析
- Author(s)
  上野貴之、川崎清史
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23590095
[Presentation] 大腸菌W3110株の鞭毛形成は細胞外分泌小胞の分泌を誘導する
- Author(s)
  眞鍋貴行、加藤まゆ、川崎清史
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23590095
[Presentation] リポ多糖刺激によるTHP1細胞からのTNF-α分泌に異物貪食が協調的に作用する
- Author(s)
  上野貴之、川崎清史
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-23590095
[Presentation] 大腸菌W3110株のOuter Membrane Vesicle分泌には鞭毛形成が重要である
- Author(s)
  眞鍋貴行、加藤まゆ、川崎清史
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡国際会議場他（福岡県）
- Data Source
  KAKENHI-PROJECT-23590095

1. NISHIJIMA Masahiro (60072956)

# of Collaborated Projects: 5 results

# of Collaborated Products: 9 results
2. SAITO Kyoko (70235034)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. HANADA Kentaro (30192701)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KUGE Osamu (30177977)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. OHGA Youko (50178000)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. FUKASAWA Masayoshi (20291130)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KAWASAKI Kiyoshi 川崎 清史

KAWASAKI Kiyosi 川崎 清史

Research Projects

Research Products

Co-Researchers

自然免疫の応答性を調節する抗菌ペプチド等に関する研究Principal Investigator

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Infectious disease drug discovery research using substances that attack and defend between organisms such as endotoxins and antimicrobial peptidesPrincipal Investigator

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Creation of a low toxic derivative biosynthesis system for biologically active substances derived from bacteria such as endotoxinPrincipal Investigator

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Lipopolysaccharide remodeling in bacterial adaptation to hostPrincipal Investigator

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Research for host-recognition and responses against endotoxin modified by pathogenic bacteria.Principal Investigator

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Study on the formation and function of exosomes

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Research for outer membrane remodeling in Salmonella entericaPrincipal Investigator

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Study for the factor involved in endotoxin ercognitionPrincipal Investigator

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マクロファージによる異物認識の分子的基盤に関する研究

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マクロファージによる異物認識の分子的基盤に関する研究

Principal Investigator

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Review Section

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ニワトリ細胞株を利用したミトコンドリアリン脂質の細胞機能に関する遺伝生化学的研究Principal Investigator

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The role of host cell membrane lipids in infection of microorganisms and in host defense mechanisms

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CD14欠損変異株を利用したリポ多糖によるマクロファージ活性化機構の研究Principal Investigator

Principal Investigator

Project Period (FY)

KAWASAKI Kiyoshi 川崎清史

KAWASAKI Kiyosi 川崎清史