Fukuda Hideko 福田秀子 (曽根秀子)

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曽根秀子

Sone Hideko 福田秀子

FUKUDA HIDEKO 福田秀子(曽根秀子)

福田秀子フクダヒデコ

曽根秀子

福田秀子(曽根秀子) フクダヒデコ

SONE Hideko 曽根秀子

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Researcher Number	60280715
Other IDs
Affiliation (Current)	2025: 横浜薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 横浜薬科大学, 薬学部, 教授 2018: 横浜薬科大学, 薬学部, 教授 2016 – 2017: 国立研究開発法人国立環境研究所, 環境リスク・健康研究センター, 室長 2015: 国立研究開発法人国立環境研究所, 環境リスク研究センター, 室長 2012 – 2014: 独立行政法人国立環境研究所, 環境リスク研究センター, 室長 … More 2006 – 2008: 独立行政法人国立環境研究所, 環境リスク研究センター, 主任研究員 1997: NIES, 地域環境研究グループ・化学物質健康リスク評価チーム, 主任研究員 1997: 国立環境研究所, 地域環境研究グループ化学物質健康リスク評価チーム, 主任研究員 1996: 国立環境研究所, 地域環境研究グループ, 主任研究員 Less
Review Section/Research Field	Principal Investigator Environmental impact assessment/Environmental policy / Basic Section 63040:Environmental impact assessment-related / Environmental risk control and evaluation / 老化(加齢) Except Principal Investigator Basic Section 47060:Clinical pharmacy-related
Keywords	Principal Investigator 化学物質 / 化学物質管理 / in vitro / 予測手法 / 発生毒性 / 因果探索 / 機械学習 / スクリーニング / 環境 / バイオインフォマティクス … More / 生殖発生毒性 / 予防対策 / エピジェネティクス / 放射線 / 毒性予測 / 幹細胞 / 有害物質 / 影響評価 / エピジェネティック / oxidative stress / lacI transgenic / LEC rats / gencmic instability / hepatitis / liver cancer / aging / Big Blue / 変異頻度 / 銅 / 自然発症 / 酸化ストレス / lacIトランスジェニック / LECラット / ゲノム不安定性 / 肝炎 / 肝がん / 加齢 / 動態 / 組織 / 共焦点レーザー顕微鏡 / ナノ毒性 / 点鼻投与 / 樹状分子 / デンドリマー / 脳 / 毒性 / 細胞 / 生体影響評価 / 健康 / 環境リスク / ナノマテリアル / マルチプロファイリング / 遺伝子発現ネットワーク / レチノイン酸 / マウス胚性幹細胞 / システムバイオロジー / ゲノムネットワーク / 次世代環境影響評価 / 健康影響評価 / 影響評価手法 … More Except Principal Investigator ヒト多能性幹細胞 / 構造活性相関 / 有害事象自発報告データベース / ジンセノサイド / 生薬人参 / 報告オッズ比 / 神経変性疾患モデル / 医薬品副作用データベース報告 / ヒト脳オルガノイド神経変性疾患モデル / 医薬品副作用データベース / ヒト脳オルガノイド / ヒトiPS細胞 / 計算機科学的解析 / 生薬人参成分ジンセノサイド / 神経変性疾患 Less

Development of innovative prediction methods for the developmental toxicity of chemicals using causal exploration with machine learningPrincipal Investigator
- Principal Investigator
  
  福田秀子 (曽根秀子)
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63040:Environmental impact assessment-related
- Research Institution
  Yokohama College of Pharmacy
Comprehensive studies for effects of Panax ginseng on neurodegenerative diseases
- Principal Investigator
  
  Kikegawa Mami
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Yokohama College of Pharmacy
Detection of chemical substances with epigenetic activity to protect environmental risk by the adverse outcome pathway approachPrincipal Investigator
- Principal Investigator
  
  Sone Hideko
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Environmental risk control and evaluation
- Research Institution
  Yokohama College of Pharmacy
  National Institute for Environmental Studies
Health assessment of PAMAM dendrimer with a spherical dendritic structurePrincipal Investigator
- Principal Investigator
  
  FUKUDA HIDEKO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Environmental impact assessment/Environmental policy
- Research Institution
  National Institute for Environmental Studies
Development study of the prediction system using mouse ES cells to detect next generation influencesPrincipal Investigator
- Principal Investigator
  
  SONE Hideko
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental impact assessment/Environmental policy
- Research Institution
  National Institute for Environmental Studies
Analysis on genomic Instability with aging in rats developed spontaneous hepaticis hepatoma Senior Research ScientistPrincipal Investigator
- Principal Investigator
  
  SONE Hideko
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  老化(加齢)
- Research Institution
  National Institute For Environmental Studies (NIES)

[Book] 「人参養栄湯に関する包括的な薬理作用の探索」漢方薬・生薬研究の最前線 ―臨床応用を主眼として月刊「細胞」2022年12月臨時増刊号2022
- Author(s)
  亀卦川真美,曽根秀子
- Total Pages
  6
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-21K06653
[Book] DMEM 溶液中Alexa488 標識PAMAM-NH2 デンドリマーのSPM による挙動解析2013
- Author(s)
  曽根秀子
- Total Pages
  1
- Publisher
  ナノテクノロジープラットフォーム報告書
- Data Source
  KAKENHI-PROJECT-24241013
[Book] DMEM 溶液中PAMAM-NH2 デンドリマーのSPM による挙動解析2013
- Author(s)
  曽根秀子
- Total Pages
  1
- Publisher
  ナノテクノロジープラットフォーム報告書
- Data Source
  KAKENHI-PROJECT-24241013
[Book] DMEM 溶液中PAMAM-PEG デンドリマーのSPM による挙動解析2013
- Author(s)
  曽根秀子
- Total Pages
  1
- Publisher
  ナノテクノロジープラットフォーム報告書
- Data Source
  KAKENHI-PROJECT-24241013
[Book] 環境安全：新素材として開発されるナノデンドリマーとその生物学的影響2013
- Author(s)
  曽根秀子
- Total Pages
  4
- Publisher
  東京大学環境安全研究センター
- Data Source
  KAKENHI-PROJECT-24241013
[Book] High-Performance Gene Expression Module Analysis Tool and Its Application to Chemical Toxicity Data. In : Furuseki H. ed., Reverse chemical genetics2009
- Author(s)
  Fujibuchi W, Kim H, Okada Y, Taniguchi T and Sone H.
- Publisher
  Humana Press Publ.
- Data Source
  KAKENHI-PROJECT-18310025
[Book] Gene Expression Signatures of Environmental Chemicals in Cancer and in Developmental Disorders. In "XIV Biennial Meeting of the Society for Free Radical Research International"2009
- Author(s)
  Sone H, Imanishi S, Nagano R, Akanuma H, Fukuda T, Ohsako S.
- Publisher
  MEDIMOND SRL Publ.
- Data Source
  KAKENHI-PROJECT-18310025
[Book] Does maternal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induce glutathione S-transferase-positive hepatic foci in adult rats? In: Morita M. ed., Persistent organic Pollutants (POPS) Research in Asia2008
- Author(s)
  Sone H, Miyabara Y, Fukuda T, Okura M, Ohsako S, Yonemoto J.
- Data Source
  KAKENHI-PROJECT-18310025
[Journal Article] Molecular profiling of ginsenoside metabolites to identify estrogen receptor α activity.2022
- Author(s)
  Kikegawa M, Nakajima A, Yu J, Asai M, Uesawa Y, Sone H
- Journal Title
  
  Gene
  
  Volume: 813 Pages: 146108-146108
- DOI
  10.1016/j.gene.2021.146108
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07070, KAKENHI-PROJECT-21K06653
[Journal Article] Epigenetic Effects of Exposure to Insecticide on Early Differentiation of Mouse Embryonic Stem Cells2019
- Author(s)
  Wang W, Otsuka S, Nansai H, Ito T, Abe K, Nakao Y, Ohgane J, Yoneda M, Sone H
- Journal Title
  
  bioRxiv
  
  Volume: なし Pages: 628487-628487
- DOI
  10.1101/628487
- Data Source
  KAKENHI-PROJECT-15H01749
[Journal Article] Expression of human mutant cyclin dependent kinase 4, Cyclin D and telomerase extends the life span but does not immortalize fibroblasts derived from loggerhead sea turtle (Caretta caretta).2018
- Author(s)
  Fukuda T, Eitsuka T, Donai K, Kurita M, Saito T, Okamoto H, Kinoshita K, Katayama M, Nitto H, Uchida T, Onuma M, Sone H, Inoue-Murayama M, Kiyono T.
- Journal Title
  
  Sci Rep
  
  Volume: 8 Issue: 1 Pages: 9229-9229
- DOI
  10.1038/s41598-018-27271-x
- NAID
  120006979734
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07803, KAKENHI-PROJECT-17K19426, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PROJECT-15H01749, KAKENHI-PROJECT-17H03624, KAKENHI-PLANNED-25118005, KAKENHI-PROJECT-26252064, KAKENHI-PROJECT-16H05801
[Journal Article] Stem Cell-Based Methods to Predict Developmental Chemical Toxicity2018
- Author(s)
  Takahashi H, Qin XY, Sone H, Fujibuchi W
- Journal Title
  
  Methods Mol Biol
  
  Volume: なし Pages: 475-483
- DOI
  10.1007/978-1-4939-7899-1_21
- ISBN
  9781493978984, 9781493978991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H01749
[Journal Article] Construction of a High-precision Chemical Prediction System Using Human ESCs2018
- Author(s)
  山根順子，油谷幸代，今西哲，赤沼宏美，永野麗子，加藤毅，曽根秀子，大迫誠一郎，藤渕航
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 138 Issue: 6 Pages: 815-822
- DOI
  10.1248/yakushi.17-00213-2
- NAID
  130007382228
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2018-06-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H01749, KAKENHI-PROJECT-15H02830
[Journal Article] Multiparameter Phenotypic Profiling in MCF-7 Cells for Assessing the Toxicity and Estrogenic Activity of Whole Environmental Water.2018
- Author(s)
  Wang W, Tada M, Nakajima D, Sakai M, Yoneda M, Sone H
- Journal Title
  
  Environ Sci Technol
  
  Volume: 52 Issue: 16 Pages: 9277-9284
- DOI
  10.1021/acs.est.8b01696
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H01749
[Journal Article] Prediction of Developmental Chemical Toxicity based on Gene Networks of Human Embryonic Stem Cells2016
- Author(s)
  Yamane J, Aburatani S, Imanishi S, Akanuma H, Nagano R, Kato T, Sone H, Ohsako S and Fujibuchi W
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 未定
- NAID
  120005763870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H01749
[Journal Article] Prediction of developmental chemical toxicity based on gene networks of human embryonic stem cells.2016
- Author(s)
  Yamane J, Aburatani S, Imanishi S, Akanuma H, Nagano R, Kato T, Sone H, Ohsako S, Fujibuchi W.
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 44(12) Issue: 12 Pages: 5515-5528
- DOI
  10.1093/nar/gkw450
- NAID
  120005763870
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H01749, KAKENHI-PROJECT-26670327, KAKENHI-PROJECT-15H02830
[Journal Article] Effects of Chronic Low-Dose Radiation on Human Neural Progenitor Cells.2016
- Author(s)
  Katsura M, Cyou-Nakamine H, Zen Q, Zen Y, Nansai H, Amagasa S, Kanki Y, Inoue T, Kaneki K, Taguchi A, Kobayashi M, Kaji T, Kodama T, Miyagawa K, Wada Y, Akimitsu N, Sone H.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 20027-20027
- DOI
  10.1038/srep20027
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26250041, KAKENHI-PROJECT-15K12202, KAKENHI-PROJECT-26670397, KAKENHI-PROJECT-26710013, KAKENHI-PROJECT-15H01749
[Journal Article] Effects of PAMAM dendrimers in the mouse brain after a single intranasal instillation2014
- Author(s)
  Tin-Tin-Win-Shwe, Sone H., Kurokawa Y., Zeng Y., Zeng Q., Nitta H., Hirano S.
- Journal Title
  
  Toxicol Letter
  
  Volume: 228 Issue: 3 Pages: 207-215
- DOI
  10.1016/j.toxlet.2014.04.020
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24241013
[Journal Article] XIV Biennial Meeting of the Society for Free Radical Research International2009
- Author(s)
  Sone H
- Journal Title
  
  MEDIMOND SRL
  
  Pages: 245-251
- Data Source
  KAKENHI-PROJECT-18310025
[Journal Article] Perinatal exposure of female rats to 2,3,7,8-tetrachlorodibenzo-p-dioxin induces central precocious puberty in the offspring.2008
- Author(s)
  Kakeyama M, Sone H, Tohyama C.
- Journal Title
  
  J Endocrinol. May 197(2)
  
  Pages: 351-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310025
[Journal Article] Persistent organic Pollutants (POPS) Research in Asia2008
- Author(s)
  Sone H
- Journal Title
  
  Morita M(自費出版)
  
  Pages: 257-261
- Data Source
  KAKENHI-PROJECT-18310025
[Journal Article] 環境化学物質の子どもへの健康影響を探る-男児生殖器異常症のインフォマティクスを用いた疾患感受性遺伝子の探索2008
- Author(s)
  曽根秀子
- Journal Title
  
  ビオフィリア 4(2)
  
  Pages: 25-29
- Data Source
  KAKENHI-PROJECT-18310025
[Journal Article] 環境化学物質の子どもへの健康影響を探る-男児生殖器異常症のインフォマティクスを用いた疾患感受性遺伝子の探索、一塩基多型SNPを指標として2008
- Author(s)
  曽根秀子、米元純三
- Journal Title
  
  ビオフィリア 4(2)
  
  Pages: 25-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310025
[Journal Article] Estrogen-responsive genes newly found to be modified by TCDD exposure in human cell lines and mouse systems2007
- Author(s)
  Tanaka J, Yonemoto J, Zaha H, Kiyama R and Sone H
- Journal Title
  
  Mol Cell Endocrinol. Jun 30 272(1-2)
  
  Pages: 38-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310025
[Journal Article] Gene interaction network analysis suggests differences between high and low doses of acetaminophen2006
- Author(s)
  Toyoshiba H, Sone H, Yamanaka T, Parham FM, Irwin RD, Boorman GA, Portier CJ
- Journal Title
  
  Toxicol Appl Pharmacol. Sep 15 215(3)
  
  Pages: 306-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310025
[Journal Article] Comparative analysis of gene networks at multiple doses and time points in livers of rats exposed to acetaminophen.2006
- Author(s)
  Portier CJ, Toyoshiba H, Sone H, Parham F, Irwin RD, Boorman GA.
- Journal Title
  
  ALTEX. 23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310025
[Patent] 胎生プログラミングに対する影響を評価するための方法2009
- Inventor(s)
  曽根秀子、永野麗子、大迫誠一郎、宮崎航、今西哲、赤沼宏美
- Industrial Property Rights Holder
  国立環境研究所
- Industrial Property Number
  2009-081497
- Filing Date
  2009-03-30
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] iPS細胞由来マイクロオルガノイドを用いたin vitro神経発達毒性評価法の開発2022
- Author(s)
  本元恒越,嶋津知美,伊藤智彦,速水耕介,曽根秀子
- Organizer
  フォーラム2022　衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-21K06653
[Presentation] Air pollution exhibits multiple key characteristics of carcinogens2019
- Author(s)
  曽根秀子
- Organizer
  IUTOX
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01749
[Presentation] エピジェネティック毒性の検出シスムに関する開発研究2018
- Author(s)
  曽根秀子
- Organizer
  第45回日本毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-15H01749
[Presentation] 神経前駆細胞分化の転写ネットワークに低線量放射線が与える変化と影響2018
- Author(s)
  桂真理、戸澤英人、南斎ひろ子、小野久子、小林美佳、田口明糸、石川夕記子、興梠貴英、曽根秀子、和田洋一郎
- Organizer
  第61回　日本放射線影響学会
- Data Source
  KAKENHI-PROJECT-15H01749
[Presentation] 多能性幹細胞を用いたエストロゲン様物質のエピジェネティック毒性に関する研究2018
- Author(s)
  大塚　悟史、南齋　ひろ子、伊藤　智彦、中尾　洋一、曽根　秀子
- Organizer
  第21回環境ホルモン学会研究発表会
- Data Source
  KAKENHI-PROJECT-15H01749
[Presentation] 生殖・発生毒性とエピジェネティック制御2018
- Author(s)
  曽根秀子
- Organizer
  第35回生殖・発生毒性学東京セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-15H01749
[Presentation] 多能性幹細胞を用いたエピジェネティック毒性物質スクリーニング2018
- Author(s)
  大塚　悟史、南齋　ひろ子、伊藤　智彦、阿部　訓也、中尾　洋一、曽根　秀子
- Organizer
  第45回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-15H01749
[Presentation] ヒトES細胞を用いた高精度の化合物毒性予測システムの構築2017
- Author(s)
  山根順子、油谷幸代、今西哲、赤沼宏美、加藤毅、曽根秀子、大迫誠一郎、藤渕航
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城）
- Year and Date
  2017-03-24
- Invited
- Data Source
  KAKENHI-PROJECT-15H01749
[Presentation] 転写制御を介して低線量放射線が網膜神経節細胞の分化に与える影響2017
- Author(s)
  桂真理、戸澤英人、南斎ひろ子、小野久子、田口明糸、興絽貴英、曽根秀子、和田洋一郎
- Organizer
  第60回　日本放射線影響学会
- Data Source
  KAKENHI-PROJECT-15H01749
[Presentation] iPS細胞から分化中の網膜神経節細胞に対する各種ストレスの影響2017
- Author(s)
  桂真理、南斎ひろ子、曽根秀子
- Organizer
  第121回日本眼科学会総会
- Place of Presentation
  東京国際フォーラム（東京）
- Year and Date
  2017-04-07
- Data Source
  KAKENHI-PROJECT-15H01749
[Presentation] Phenotypic variation in the cloned pigs with heterozygous fibrillin-1 mutation.2017
- Author(s)
  Kazuhiro Umeyama, Yoshikazu Arai, Kazuaki Nakano, Tooru Fukuda, Ikuma Umeki, Ayuko Uchikura, Yuri Kasai, Hitomi Matsunari, Masaki Nagaya, Masahito Watanabe, Jun Ohgane and Hiroshi Nagashima
- Organizer
  4th World Congress of Reproductive Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01749
[Presentation] iPS細胞から分化中の網膜神経節細胞に対する各種ストレスの影響 Effects of irradiations on proliferation and differentiation of retinal ganglion cells from induced pluripotent stem cells2017
- Author(s)
  桂　真理、南齋ひろ子、曽根秀子
- Organizer
  第121回日本眼科学会学術総会
- Data Source
  KAKENHI-PROJECT-15H01749
[Presentation] iPS細胞から網膜神経節細胞への分化に対する放射線影響 Radiation effects on differentiation of induced pluripotent stem cells to retinal ganglion cells2017
- Author(s)
  桂　真理、戸澤英人、南齋ひろ子、小野久子、田口明糸、小林美佳、興梠貴英、高橋政代、和田洋一郎、曽根秀子
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-15H01749
[Presentation] エピジェネティック毒性物質の検出システムの開発2016
- Author(s)
  曽根秀子、阿部訓也、中尾洋一、大鐘潤、桂真理、藤渕航、五十嵐勝秀
- Organizer
  第43回日本毒性学会学術年会
- Place of Presentation
  ウインクあいち(愛知）
- Year and Date
  2016-06-30
- Invited
- Data Source
  KAKENHI-PROJECT-15H01749
[Presentation] Effects of Low- Dose Radiation From Cs-137 on Normal Human Cell2015
- Author(s)
  Nobuyoshi Akimitsu, Mari Katsura, Azusa Ishibashi, Hiromasa Nakamine, Kazuyuki Tao, Toshiyuki Kaji, Hideko Sone, Tatsuhiko Kodama, Kiyoshi Miyagawa, Youichirou Wada
- Organizer
  ICRR 2015 (15th International Congress of Radiation Research)
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2015-05-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01749
[Presentation] Effects of Low- and Middle- Dose Rate Radiation on Human Neural Precursor Cells2015
- Author(s)
  Mari Katsura, Hiromasa Nakamine, Hideko Sone, Shota Amagasa, Toshiyuki Kaji, Kiyoshi Miyagawa, Youichirou Wada, Nobuyoshi Akimitsu
- Organizer
  ICRR 2015 (15th International Congress of Radiation Research)
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2015-05-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01749
[Presentation] Determinations of PAMAM particles in culture media by using scanning probe microscopy techniques for the exposure assessment.2013
- Author(s)
  Hideko Sone, Yoshika Kurokawa,Tin-Tin Win-Shwe, Yang Zeng, Qin Zeng, Seishiro Hirano
- Organizer
  The 6th International Symposium on Nanotechnology, Occupational and Environmental Health
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24241013
[Presentation] Intracellular distribution of Alexa 488 labeled-PAMAM-NH2 in human cells for prediction of permeability into blood-brain barrier2013
- Author(s)
  Y Kurokawa,Tin-Tin Win-Shwe, Y Zeng, Q Zeng, S Hirano, H Sone
- Organizer
  The 6th International Symposium on Nanotechnology, Occupational and Environmental Health
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24241013
[Presentation] Biological effects and biodistribution of PAMAM-NH2 dendrimers in a mouse brain and human ES cell-derived neurons.2013
- Author(s)
  Tin-Tin Win-Shwe, Hideko Sone, Yoshika Kurokawa, Yang Zeng, Qin Zeng, Hiroshi Nitta, Seishiro Hirano
- Organizer
  The 6th International Symposium on Nanotechnology, Occupational and Environmental Health
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24241013
[Presentation] ヒト細胞におけるナノサイズＰＡＭＡＭデンドリマーの光学的観察と細胞内挙動2012
- Author(s)
  曽根秀子
- Organizer
  第39回日本毒性学会学術年会
- Place of Presentation
  宮城県仙台市
- Data Source
  KAKENHI-PROJECT-24241013
[Presentation] PAMAMデンドリマーのヒトES由来胚様体及び神経系分化細胞への分子送達に関する研究2012
- Author(s)
  曽根秀子
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  北海道札幌市
- Data Source
  KAKENHI-PROJECT-24241013
[Presentation] Stage-Specific Gene profiling during neural differentiation of mouse embryonic stem cells2009
- Author(s)
  Akanuma h., Nagano R., Imanishi S., Toyoshiba H., Sone H
- Organizer
  48th Annual Meeting of Society of Toxicology. 2008
- Place of Presentation
  Baltimore
- Year and Date
  2009-03-18
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] Prenatal Exposure to Permethrin Causes Vascular Malformation in Fetal Brain and Decreases Motility of Adult Mice2009
- Author(s)
  Imanishi S, Akanuma H, Okura M, Sone H.
- Organizer
  48th Annual Meeting of Society of Toxicology
- Place of Presentation
  Baltimore
- Year and Date
  2009-03-19
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] 化学物質の毒性予測及びリスク評価手法確立のための基盤システムの構築2008
- Author(s)
  曽根秀子, 黄倉雅広
- Organizer
  第4回日本バイオインフォマティクス学会:オントロジー研究会
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] Stage-Specific Gene profiling during neural differentiation of mouse embryonic stem cells.2008
- Author(s)
  Akanuma H, Nagano R, Imanishi S, Toyoshiba H, Sone H.
- Organizer
  48th Annual Meeting of Society of Toxicology
- Place of Presentation
  Baltimore
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] マウスES細胞を用いたマルチプロファイリング技術による化学物質の影響評価の開発2008
- Author(s)
  永野麗子、小池上繁、今西哲、赤沼宏美、宮崎航、大迫誠一郎、黄倉雅広、曽根秀子
- Organizer
  第11回日本内分泌撹乱化学物質学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] 化学物質の毒性予測及びリスク評価手法確立のための基盤システムの構築2008
- Author(s)
  曽根秀子黄倉雅広
- Organizer
  第4回日本バイオインフォマティクス学会:オントロジー研究会
- Place of Presentation
  東京
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] A Genome Informatics and Epidemiological Study Identifies Alleles in Arnt2 associated with Risk of Hypospadias and Micropenis.2008
- Author(s)
  Sone H and Yonemoto J.
- Organizer
  28th Int. Symp. Halogenat. Persistent Org. pollut.-Dioxin 2008
- Place of Presentation
  Birmingham
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] Evaluation of Vascular Toxicity of Permethrin in Human Endothelial Cell and Mouse ES Cell2008
- Author(s)
  Satoshi Imanishi, Junzo Yonemoto, Hideko Sone
- Organizer
  SOT Annual meeting
- Place of Presentation
  Seattle
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] ES細胞から神経系の分化過程における遺伝子ネットワーク解析2008
- Author(s)
  赤沼宏美、永野麗子、小池上繁、今西哲、豊柴博義、黄倉雅広、曽根秀子
- Organizer
  第11回日本内分泌撹乱化学物質学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] A Genome Informatics and Epidemiological Study Identifies Alleles in Arnt2 associated with Risk of Hypospadias and Micropenis2008
- Author(s)
  Sone H, Yonemoto J
- Organizer
  28th Int. Symp. Halogenat. Persistent Org. pollut. -Dioxin 2008
- Place of Presentation
  Birmingham
- Year and Date
  2008-08-20
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] ヒト血管内皮細胞とマウスES細胞を用いたペルメトリンの血管毒性の評価2008
- Author(s)
  今西哲・米元純三・曽根秀子
- Organizer
  第11回日本内分泌撹乱化学物質学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] Cellular image profiling of neural differentiation pattern of mouse embryonic stem cells with morphological information2008
- Author(s)
  Nagano R, Shigeru K, Imanishi S, Ohsako S, Zaha H, Ohkura M, Yonemoto J, and Sone H.
- Organizer
  第41回日本発生生物学会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] Gene Expression Signatures of Environmental Chemicals in Cancer and in Developmental Disorders2008
- Author(s)
  Sone H, Imanishi S, Nagano R, Akanuma H, Fukuda T, Ohsako S.
- Organizer
  14th Biennial Meeting of the Society for Free Radical Research International
- Place of Presentation
  Beijing
- Year and Date
  2008-10-20
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] レチノイン酸によるマウスES細胞の分化・増殖への影響に関する研究2007
- Author(s)
  永野麗子、小池上繁、今西哲、座波ひろこ、米元純三、曽根秀子
- Organizer
  環境ホルモン学会第10回研究発表会12
- Place of Presentation
  埼玉
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] Bayesian Network Analysis on Cell Morphology.2007
- Author(s)
  Koikegami S and Sone H.
- Organizer
  日本バイオインフォマティクス学会12
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] A Framework for the Development of a Prediction System for Determining the Effects of Exposure to Environmental Chemicals on Children's Health.2007
- Author(s)
  Sone H
- Organizer
  International Science Forum on Computational Toxicology
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] レチノイン酸によるマウスES細胞の分化・増殖への影響に関する研究2007
- Author(s)
  永野麗子、小池上繁、今西哲、座波ひろこ、米元純三、曽根秀子
- Organizer
  環境ホルモン学会第10回研究発表会
- Place of Presentation
  埼玉
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] A Framework for the Development of a Prediction System for Determining the Effects of Exposure to Environmental Chemicals on Children's Health2007
- Author(s)
  曽根秀子
- Organizer
  International Science Forum on Computational Toxicology
- Place of Presentation
  米国・RTP
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] 殺虫剤ペルメトリンがヒト脳毛細血管内皮細胞に及ぼす影響2007
- Author(s)
  今西哲、米元純三、曽根秀子
- Organizer
  環境ホルモン学会第10回研究発表会
- Place of Presentation
  埼玉
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] A Microarray-Oriented Dioxin-Response Gene Database (DRGdb) Built in the National Institute for Environmental Studies, Japan.2007
- Author(s)
  Ohsako S, Nishikawa D, Ogi S, Hamada K, Sone H.
- Organizer
  International Science Forum on Computational Toxicology
- Place of Presentation
  North Calorina, USA
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] Establishment of a System using Mouse Embryonic Stem Cells to Evaluate for the Effects of Chemicals on Development2007
- Author(s)
  曽根秀子
- Organizer
  6th World Congress on Alternative&Animal Use in the Life Sciences
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] Bayesian Network Analysis on Cell Morphology2007
- Author(s)
  Koikegami H, Hideko Sone
- Organizer
  日本バイオインフォマティクス学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] 遺伝子ネットワーク推定を利用した環境化学物質及び薬剤の類型化手法の開発に関する研究2006
- Author(s)
  曽根秀子、豊柴博義
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] 発がんに関わる内分泌かく乱化学物質の影響予測システム構築に関する研究2006
- Author(s)
  曽根秀子、座波ひろ子、黄倉雅広、米元純三
- Organizer
  環境ホルモン学会第9回研究発表会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18310025
[Presentation] Mechanism study of polyamidoamine (PAMAM) dendrimers nanoparticle induced neurotoxicity
- Author(s)
  Yang Zenga, Tin-Tin Win-Shwe, Qin Zeng, Yoshika Kurokawa, Hiroko Nansai, Zhen Ya Zhang, Hideko Sone
- Organizer
  環境ホルモン学会第17回研究発表会
- Place of Presentation
  東京大学山上会館（東京都文京区）
- Year and Date
  2014-12-09 – 2014-12-10
- Data Source
  KAKENHI-PROJECT-24241013
[Presentation] ベイジアンネットワーク解析によるナノマテリアルの毒性予測に関する研究
- Author(s)
  曽根秀子, 曾洋, 南齋ひろ子
- Organizer
  第３回生命医薬情報学連合大会（IIBMP2014）
- Place of Presentation
  仙台国際センター（宮城県仙台市
- Year and Date
  2014-10-02 – 2014-10-04
- Data Source
  KAKENHI-PROJECT-24241013
[Presentation] デンドリマーナノ粒子の神経発達毒性（in vitro 研究）
- Author(s)
  黒河佳香、曾洋、曾勤、Tin-Tin Win Shwe、平野靖史郎、曽根秀子
- Organizer
  第３７回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-24241013

1. NAGANO Reiko (20455249)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
2. IMANISHI Satoshi (50462479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
3. ZAHA Hiroko (10391111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. YAMZAKI Shin (80391168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TOYOSHIBA Hiroyoshi (40315073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
6. AKANUMA Hiromi (70534155)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
7. OHSAKO Seiichiroh (00274837)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. KUROKAWA Yoshika (30205231)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. WIN-SHWE TINTIN (00391128)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Kikegawa Mami (30896626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 伊藤智彦 (60391067)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. 桂真理 (30436571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
13. 藤渕航 (60273512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
14. 大鐘潤 (50313078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. 中尾洋一 (60282696)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
16. 阿部訓也 (40240915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
17. 玉田嘉紀 (80435495)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 加藤毅 (40401236)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. HIRANO Seishiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
20. ZENG Yang

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
21. MATSUI Yasuto

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. KIMURA Hiroyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. YAMAZAKI Masashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. HAYAMA Kazumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. Nansai Hiroko

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
26. Kondo Masayo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. Suzuki Shinnosuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. Otsuka Satoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
29. ASAI Masashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. EITSUKA Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. KANKI Yasuharu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. TIN・TIN Win・Shwe

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
33. 和田洋一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fukuda Hideko 福田 秀子 (曽根 秀子)

曽根秀子

Sone Hideko 福田 秀子

FUKUDA HIDEKO 福田 秀子(曽根秀子)

福田 秀子 フクダ ヒデコ

曽根 秀子

福田 秀子(曽根秀子) フクダ ヒデコ

SONE Hideko 曽根 秀子

Research Projects

Research Products

Co-Researchers

Development of innovative prediction methods for the developmental toxicity of chemicals using causal exploration with machine learningPrincipal Investigator

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Comprehensive studies for effects of Panax ginseng on neurodegenerative diseases

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Detection of chemical substances with epigenetic activity to protect environmental risk by the adverse outcome pathway approachPrincipal Investigator

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Research Institution

Health assessment of PAMAM dendrimer with a spherical dendritic structurePrincipal Investigator

Principal Investigator

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Development study of the prediction system using mouse ES cells to detect next generation influencesPrincipal Investigator

Principal Investigator

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Analysis on genomic Instability with aging in rats developed spontaneous hepaticis hepatoma Senior Research ScientistPrincipal Investigator

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[Book] 「人参養栄湯に関する包括的な薬理作用の探索」漢方薬・生薬研究の最前線 ―臨床応用を主眼として月刊「細胞」2022年12月臨時増刊号2022

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[Book] DMEM 溶液中Alexa488 標識PAMAM-NH2 デンドリマーのSPM による挙動解析2013

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[Book] DMEM 溶液中PAMAM-NH2 デンドリマーのSPM による挙動解析2013

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[Book] DMEM 溶液中PAMAM-PEG デンドリマーのSPM による挙動解析2013

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[Book] 環境安全：新素材として開発されるナノデンドリマーとその生物学的影響2013

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[Book] High-Performance Gene Expression Module Analysis Tool and Its Application to Chemical Toxicity Data. In : Furuseki H. ed., Reverse chemical genetics2009

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[Book] Gene Expression Signatures of Environmental Chemicals in Cancer and in Developmental Disorders. In "XIV Biennial Meeting of the Society for Free Radical Research International"2009

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Fukuda Hideko 福田秀子 (曽根秀子)

Sone Hideko 福田秀子

FUKUDA HIDEKO 福田秀子(曽根秀子)

福田秀子フクダヒデコ

曽根秀子

福田秀子(曽根秀子) フクダヒデコ

SONE Hideko 曽根秀子