Higashitsuji Hiroaki 東辻宏明

… Alternative Names

HIGASHITSUJI Hiroaki 東辻宏明

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Researcher Number	60281094
Other IDs
External Links
Affiliation (Current)	2025: 京都大学, 医学研究科, 助教
Affiliation (based on the past Project Information) *help	2012 – 2014: 京都大学, 医学(系)研究科(研究院), 助教 2007 – 2010: Kyoto University, Graduate School of Medicine, assistant professor 1996 – 2006: 京都大学, 医学研究科, 助手 1999: 京都大学, 大学院・医学研究科, 助手
Review Section/Research Field	Principal Investigator Gastroenterology / Gastroenterology / Biological Sciences / Experimental pathology Except Principal Investigator Hematology / Urology / Biological Sciences / Neurology / Obstetrics and gynecology / Gastroenterology
Keywords	Principal Investigator がん遺伝子 / プロテアソーム / ユビキチン / 肝がん / 肝癌 / 26Sプロテアソーム / がん抑制遺伝子 / タンパク分解 / アポトーシス / MDM2 … More / hepatocellular carcinoma / トランスジェニックマウス / proteasome / tumor suppressor / oncogene / hepatoma / 蛋白分解 / 肝細胞癌 / ガンキリン / hepatocarcinogenesis / oncoprotein gankyrin / E3 ubiquitin ligase / ubiquitin / gene expression profile / pRB / proteomics / pRb / p53 / ユビキチンリガーゼ / 肝発癌 / 発癌機構 / リガーゼ / protein degradation / リン酸化 / proteolysis / retinoblastoma protein / ankyrin repeat / オンコジーン / 転写因子NFkB / がん抑制遺伝子RB / 蛋白-蛋白相互作用 / Rb蛋白 / アンキリンリピート / 癌遺伝子 / RNA結合タンパク / 相互作用 / 肝臓がん / CIRP / miRNA / homologous recombination / BRCA1 / spliceosome / CLIP / mRNA splicing / mRNA processing / RNA結合蛋白 / PIP / 原発性肝癌 / モノユビキチン / メタロベータラクタマーゼファミリー / メタロベータラクタマーゼ / アグリソーム / 転写調節 … More Except Principal Investigator レトロウイルス / 精巣 / ガンキリン / hepatocyte / HSP70 / HSP110 / APG-2 / APG-1 / vector / retrovirus / NFAT5 / cis-element / LTR / FMEV / RBM3 / CIRP / retroviral vector / 造血幹細胞 / レトロウイルス・ベクター / 造血細胞 / 停留精巣 / rbm3 / apg-2 / apg-1 / 低温ショック / 不妊症 / RT-PCR / ベクター / プロテアソーム / Hematopoietic stem cell / レトロウイルスベクター / stem cell / bone marrow / 肝細胞 / apotosis / aggregation / polyglutamine / HSP40 / 凝集体 / ポリグルタミン / アポトーシス / 凝集 / ポリグルタミン鎖 / PI4OK / レトロ・ウイルス / 遺伝子治療 / P14OK / Cryptorchidism / Cold / Testis / 不妊 / 低温ショック蛋白質 / ストレス / DNAマイクロアレー / 酵母 / 低温 / stroma / hematopoietic cell / VSV G蛋白 / GALV / シュードタイプ・ウイルス / レトロウィルス・ベクター / ストローマ細胞 / Cirp / cold shock / infertility / testis / heat shock / RNA結合蛋白質 / 精子 / rbm 3 / cirp / 熱ショック / sterility / endometrium / receptor / Sex steroid / 間質細胞 / Sex Steroid / 子宮内膜 / 受容体 / 性ステロイド / テロメラーゼ / 不死化 / Rb / p53 / テロメアーゼ / 細胞培養 / がん抑制遺伝子 / 細胞不死化 / 造腫瘍性 / がん治療 / 肝がん / がん遺伝子 / 精子形成 / 肝細胞がん / アンキリン Less

Analysis of hepatic carcinogenesis by interrelationship between RNA-binding oncogene and miRNAsPrincipal Investigator
- Principal Investigator
  
  HIGASHITSUJI Hiroaki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
Analysis of hepatocarcinogenesis due to monoubiquitylation of gankyrin that is one of the proteasome-interacting proteinsPrincipal Investigator
- Principal Investigator
  
  HIGASHITSUJI Hiroaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
Analysis of hepatocarcinogenesis via the complex between the E3 ubiquitin ligase MDM2 and gankyrinPrincipal Investigator
- Principal Investigator
  
  HIGASHITSUJI Hiroaki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
消化管上皮の初代培養細胞を不死化させる技法の開発
- Principal Investigator
  
  藤田潤
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
メタロベータラクタマーゼファミリーHSCO変異分子によるアグリソーム形成と細胞死Principal Investigator
- Principal Investigator
  
  東辻宏明
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Kyoto University
Research of a multi-stage hepatocaranogenesis by use of gankyrn tranggenic mice.Principal Investigator
- Principal Investigator
  
  HIGASHITSUJI Hiroaki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  KYOTO UNIVERSITY
Studies on the trans-differentiation of hematopoietic stem cells and the application for the gene therapy
- Principal Investigator
  
  ITOH Katsuhiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  KYOTO UNIVERSITY
がん抑制遺伝子のタンパク分解に関与するがん遺伝子ガンキリンの機能解析Principal Investigator
- Principal Investigator
  
  東辻宏明
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
がん遺伝子産物ガンキリンを標的とする肝がん治療の試み
- Principal Investigator
  
  藤田潤
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
肝細胞の発がん過程に関与する新規のがん遺伝子ガンキリンの機能解析Principal Investigator
- Principal Investigator
  
  東辻宏明
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
ガンキリンを標的とした肝細胞がん治療法の開発
- Principal Investigator
  
  藤田潤
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
レトロウイルス・ベクターを用いた.新たなトランスジュンック動物作成方法の開発
- Principal Investigator
  
  藤田潤
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Urology
- Research Institution
  Kyoto University
On the transgene expression mediated by retrouival vectors
- Principal Investigator
  
  ITO Katsuhiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  KYOTO UNIVERSITY
Functional analysis of a noveloncoprotein, gankyrin, isolated from hepatpmas, and its clinical applicationPrincipal Investigator
- Principal Investigator
  
  HIGASHITSUJI Hiroaki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  KYOTO UNIVERSITY
Studies on the effects of heat shock proteins of the HSP110 family on the aggregation of poly-glutamine
- Principal Investigator
  
  ITOH Katsuhiko, 金子嘉志
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  KYOTO UNIVERSITY
Functions and clinical significance of cold shock proteins in the testis
- Principal Investigator
  
  FUJITA Jun
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Urology
- Research Institution
  KYOTO UNIVERSITY
Development of a method for efficient transfer and expression of genes in hematopoietic cells.
- Principal Investigator
  
  ITOU Katsuhiko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  KYOTO UNIVERSITY
Functional analysis of an ankyrin repeat protein, gankyrin, overexpressed in cancers and its applicating gene therapyPrincipal Investigator
- Principal Investigator
  
  HIGASHITSUJI Hiroaki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  KYOTO UNIVERSITY
Temperature sensitive gene expression in male germ cells and its clinical signification
- Principal Investigator
  
  FUJITA Jun
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Kyoto University
Reguratory Mechanisms of Sex Steroid Receptor Expression in Human Endometria and SterilityPrincipal Investigator
- Principal Investigator
  
  HIGASHITSUJI Hiroaki, IWAI Masazumi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYOTO UNIVERSITY
  Tazuke Kofukai Medical Research Institute

All 2014 2013 2012 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation

[Journal Article] Stress response protein cirp links inflammation and tumorigenesis in colitis-associated cancer.2014
- Author(s)
  Sakurai T, Kashida H, Watanabe T, Hagiwara S, Mizushima T, Iijima H, Nishida N, Higashitsuji H, Fujita J, Kudo M.
- Journal Title
  
  Cancer Res.
  
  Volume: 74 Pages: 6119-28
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24659362
[Journal Article] Hypothermia protects against fulminant hepatitis in mice by reducing reactive oxygen species production.2013
- Author(s)
  Sakurai T, Kudo M, Watanabe T, Itoh K, Higashitsuji H, Arizumi T, Inoue T, Hagiwara S, Ueshima K, Nishida N, Fukumoto M, Fujita J.
- Journal Title
  
  Dig Dis
  
  Volume: 31 Issue: 5-6 Pages: 440-6
- DOI
  10.1159/000355242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590998, KAKENHI-PROJECT-23659202, KAKENHI-PROJECT-24590997, KAKENHI-PROJECT-24592446, KAKENHI-PROJECT-24592514, KAKENHI-PROJECT-24659174, KAKENHI-PROJECT-24659362
[Journal Article] Overexpression of gankyrin in mouse hepatocytes induces hemangioma by suppressing factor inhibiting hypoxia-inducible factor-1 (FIH-1) and activating hypoxia-inducible factor-1.2013
- Author(s)
  Liu Y, Higashitsuji H, Higashitsuji H, Itoh K, Sakurai T, Koike K, Hirota K, Fukumoto M, Fujita J.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 432(1) Pages: 22-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659362
[Journal Article] Cold-inducible RNA-binding protein (Cirp) interacts with Dyrk1b/Mirk and promotes proliferation of immature male germ cells in mice2012
- Author(s)
  Masuda T, et al.
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 109 Issue: 27 Pages: 10885-108901
- DOI
  10.1073/pnas.1121524109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20670006, KAKENHI-PROJECT-23590998, KAKENHI-PROJECT-23592330, KAKENHI-PROJECT-23659202, KAKENHI-PROJECT-23790332, KAKENHI-PROJECT-24592446, KAKENHI-PROJECT-24592514, KAKENHI-PROJECT-24659174, KAKENHI-PROJECT-24659362
[Journal Article] Identification of a novel enhancer that binds Sp1 and contributes to induction of cold-inducible RNA-binding protein (cirp) expression in mammalian cells.2012
- Author(s)
  Sumitomo Y, Higashitsuji H, Higashitsuji H, Liu Y, Fujita T, Sakurai T, et al
- Journal Title
  
  BMC Biotechnol
  
  Volume: 12 Issue: 1 Pages: 72-72
- DOI
  10.1186/1472-6750-12-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590998, KAKENHI-PROJECT-23659202, KAKENHI-PROJECT-24592446, KAKENHI-PROJECT-24592514, KAKENHI-PROJECT-24659362
[Journal Article] MDM2 is a novel E3 ligase for HIV-1 Vif.2009
- Author(s)
  Izumi T, Takari-Kondo A. Shirakawa K, Higashitsuji H, Itoh K. lo K, Matsui M, Iwai K, Kondoh H, Sato T, Tomonaga M, Ikeda S, Akari H, Koyanagi Y, Fujita J, Uchiyaima T.
- Journal Title
  
  Retrovirology 6
  
  Pages: 1-10
- NAID
  120004770229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590773
[Journal Article] MDM2 is a novel E3 ligase for HIV-1 Vif.2009
- Author(s)
  Izumi T, Takaori-Kondo A, Shirakawa K, Higashitsuji H, Itoh K, Io K, Matsui M, Iwai K, Kondoh H, Sato T, Tomonaga M, Ikeda S, Akari H, Koyanagi Y, Fujita J, Uchiyama T.
- Journal Title
  
  Retrovirology 6
  
  Pages: 1-10
- NAID
  120004770229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590773
[Journal Article] Gankyrin oncoprotein overexpression as a critical factor for tumor growth in human esophageal squamous cell carcinoma and its clinical significance.2008
- Author(s)
  Ortiz, C. M., Ito, T., Tanaka, E., Tsunoda, S., Nagayama, S., Sakai, Y., Higashitsuji, H., Fujita, J., Shimada, Y.
- Journal Title
  
  Int J Cancer 122
  
  Pages: 325-332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590773
[Journal Article] Association of gankyrin protein expression with early clinical stages and insulin-like growth factor-binding protein 5 expression in human hepatocellular carcinoma.2008
- Author(s)
  Umemura, A., Itoh, Y., Itoh, K., Yamaguchi, K., Nakajima, T., Higashitsuji, H., Oaoue H., Fukumoto, M, Okanoue, T., Fujita, J.
- Journal Title
  
  Hepatology 47
  
  Pages: 493-502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590773
[Journal Article] Association of gankyrin protein expression with early clinical stages and IGFBP-5 expression in human hepatocellular carcinoma.2008
- Author(s)
  Umemura A, Itoh Y, Itoh K, Yamaguchi K, Nakajima T, Higashitsuji H, Onoue H, Fukumoto M, Okanoue T, Fujita J.
- Journal Title
  
  Hepatology 47(2)
  
  Pages: 493-502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590773
[Journal Article] Gankyrin oncoprotein overexpression as a critical factor for tumor growth in human esophageal squamous cell carcinoma and its clinical significance.2008
- Author(s)
  Ortiz CM, Ito T, Tanaka E, Tsunoda S, Nagayama S, Sakai Y, Higashitsuji H, Fujita J, Shimada Y.
- Journal Title
  
  Int J Cancer 122
  
  Pages: 325-332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590773
[Journal Article] Enhanced deacetylation of p53 by the anti-apoptotic protein hsco in association with histone deacetylase 1.2007
- Author(s)
  Hisako Higashitsuji
- Journal Title
  
  J Biol Chem (On line publication)
- Data Source
  KAKENHI-PROJECT-18590732
[Journal Article] The oncoprotein gankyrin interacts with RelA and suppreses NF-kB activity2007
- Author(s)
  Higashitsuji, H., et. al.
- Journal Title
  
  Biochem. Biophys. Res. Commun 363
  
  Pages: 879-884
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590732
[Journal Article] The oncoprotein gankyrin interacts with RelA and suppresses NF-kBactivity.2007
- Author(s)
  Higashitsuji, H., et. al.
- Journal Title
  
  Biochem. Biophys. Res. Common. 363
  
  Pages: 879-884
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590732
[Journal Article] Enhanced deacetylation of p53 by the anti-apoptotic protein HSCO in association with HDAC1.2007
- Author(s)
  Higashitsuji, H., et. al.
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 13716-13725
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590732
[Journal Article] Enhanced deacetylation of p53 by the anti-apoptotic protein HSCO in association with HDAC1.2007
- Author(s)
  Higashitsuji H
- Journal Title
  
  J Biol Chem (印刷中)
- Data Source
  KAKENHI-PROJECT-17659213
[Journal Article] The oncoprotein gankyrin interacts with RelA and suppresses NFkappaB activity.2007
- Author(s)
  Hiroaki Higashitsuji, et. al.
- Journal Title
  
  Biochem Biophys Res Commun 363
  
  Pages: 879-884
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590732
[Journal Article] Enhanced deacetylation of p53 by the anti-apoptotic protein HSCO in association with HDAC12007
- Author(s)
  Higashitsuji, H., et. al.
- Journal Title
  
  J. Biol. Chem 282
  
  Pages: 13716-13725
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590732
[Journal Article] The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53.2005
- Author(s)
  Higashitsuji H
- Journal Title
  
  Cancer Cell 8・1
  
  Pages: 75-87
- Data Source
  KAKENHI-PROJECT-17659213
[Journal Article] Gankyrin ubiquitin-dependent proteolysis and major tumour suppressors.2005
- Author(s)
  Higashitsuji H
- Journal Title
  
  Trends in Cell Biology (印刷中)
- Data Source
  KAKENHI-PROJECT-17659213
[Journal Article] The oncoprotein gankyrin negatively regulates both p53 and RB by enhancing proteasomal degradation.2005
- Author(s)
  Higashitsuji H
- Journal Title
  
  Cell Cycle 4・10
  
  Pages: 1335-1337
- Data Source
  KAKENHI-PROJECT-17659213
[Presentation] Overexpression of gankyrin in mouse hepatocytes induces hemangioma.2013
- Author(s)
  東辻宏明、東辻久子、藤田潤
- Organizer
  第２１回JDDW２０１３
- Place of Presentation
  東京都品川区
- Data Source
  KAKENHI-PROJECT-24659362
[Presentation] ほ乳類低温ショックタンパク質Cirpは皮膚創傷治癒を促進する2013
- Author(s)
  藤田潤、東辻久子、東辻宏明
- Organizer
  第８回臨床ストレス応答学会
- Place of Presentation
  松本市、信州大学医学部付属病院、大会議室
- Data Source
  KAKENHI-PROJECT-24659362
[Presentation] 癌抑制遺伝子BRCA1の不活性型代謝系酵素による核内での機能調節2012
- Author(s)
  東辻宏明
- Organizer
  日本肝臓学会
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-24659362
[Presentation] Proto-oncogene CIRP that is induced by moderate cold temperature (32 degrees centigrade) enhances cell mobility of cancer cells2012
- Author(s)
  東辻宏明
- Organizer
  日本癌学会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-24659362
[Presentation] 肝癌で高発現するCIRP(cold-inducible RNA binding protein)は腫瘍細胞の浸潤能を亢進させる2010
- Author(s)
  東辻宏明
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形市ホテルメトロポリタン山形
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-20590773
[Presentation] 肝癌で高発現するCIRP (cold-inducible RNA binding protein)は腫瘍細胞の浸潤能を亢進させる2010
- Author(s)
  東辻宏明
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形市、ホテルメトロポリタン山形
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-20590773
[Presentation] NEDD8化ガンキリンを介したMDM2の基質特異性の変化2009
- Author(s)
  東辻宏明
- Organizer
  第95回日本消化器病学会
- Place of Presentation
  ロイトン札幌、札幌市
- Year and Date
  2009-05-09
- Data Source
  KAKENHI-PROJECT-20590773
[Presentation] NEDD88ガンキリンを介たMDM2の基質特異性の変化2009
- Author(s)
  東辻宏明
- Organizer
  第95回日本消化器病学会
- Place of Presentation
  ロイトン札幌、札幌市
- Year and Date
  2009-05-09
- Data Source
  KAKENHI-PROJECT-20590773
[Presentation] 肝癌で過剰発現するがん遺伝子ガンキリンはNFkappaB(RelA)と結合しその転写活性化能を抑制する2008
- Author(s)
  東辻宏明
- Organizer
  第44回日本肝臓学会
- Place of Presentation
  松山市、愛媛県
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-20590773
[Presentation] 肝癌で過剰発現するがん遺伝子ガンキリンはNFkappaB (RelA)と結合しその転写活性化能を抑制する2008
- Author(s)
  東辻宏明
- Organizer
  第44回日本肝臓学会
- Place of Presentation
  松山市、愛媛県
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-20590773
[Presentation] Enhanced deacetylation of p53 by the anti-apoptotic protein HSCO in association with histone deacetylase12007
- Author(s)
  Hiroaki Higashitsuji
- Organizer
  66th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Pacifico Yokohama, Yokohama
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-18590732
[Presentation] HSCOはHDAC1と複合体を形成し、p53の脱アセチル化を亢進することにより、腫瘍細胞に化学療法耐性を賦与する。2007
- Author(s)
  東辻宏明
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590732
[Presentation] Enhanced deacetylation of p53 by the anti-apoptotic protein HSCO in association with HDAC12007
- Author(s)
  Higashitsuji, Hiroaki
- Organizer
  66th annual meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama city
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590732
[Presentation] The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p532006
- Author(s)
  Higashitsuji, Hiroaki
- Organizer
  42nd annual meeting of the Japan Society of Hepatology
- Place of Presentation
  Kyoto city
- Year and Date
  2006-05-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590732
[Presentation] がん遺伝子ガンキリンによるがん抑制遺伝子p53のユビキチンプロテアソームでの分解促進。2006
- Author(s)
  東辻宏明
- Organizer
  第42回日本肝臓学会総会
- Place of Presentation
  京都市
- Year and Date
  2006-05-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590732
[Presentation] ほ乳類低温ショックタンパク質CIRPはBRCA1による相同組み替えによるDNA修復を促進する
- Author(s)
  東辻宏明
- Organizer
  第６９回日本消化器外科学会総会
- Place of Presentation
  郡山市立文化センター
- Year and Date
  2014-07-16 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-24659362

1. FUJITA Jun (50173430)

# of Collaborated Projects: 15 results

# of Collaborated Products: 2 results
2. ITOH Katsuhiko (90281097)

# of Collaborated Projects: 10 results

# of Collaborated Products: 0 results
3. KANEKO Yoshiyuki (40252465)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. IWAI Masazumi (20240822)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 西山洋 (10335276)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TSUJI Takashi

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. MORITA Keiko

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. MATSUDA Takashi (20192338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 西村慶子 (99999998)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 森田慶子(西村慶子)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 森田慶子

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KUDO Masatoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 櫻井俊治

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Higashitsuji Hiroaki 東辻 宏明

HIGASHITSUJI Hiroaki 東辻 宏明

Research Projects

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Co-Researchers

Analysis of hepatic carcinogenesis by interrelationship between RNA-binding oncogene and miRNAsPrincipal Investigator

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Analysis of hepatocarcinogenesis due to monoubiquitylation of gankyrin that is one of the proteasome-interacting proteinsPrincipal Investigator

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Analysis of hepatocarcinogenesis via the complex between the E3 ubiquitin ligase MDM2 and gankyrinPrincipal Investigator

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メタロベータラクタマーゼファミリーHSCO変異分子によるアグリソーム形成と細胞死Principal Investigator

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Research of a multi-stage hepatocaranogenesis by use of gankyrn tranggenic mice.Principal Investigator

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がん抑制遺伝子のタンパク分解に関与するがん遺伝子ガンキリンの機能解析Principal Investigator

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肝細胞の発がん過程に関与する新規のがん遺伝子ガンキリンの機能解析Principal Investigator

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Functional analysis of a noveloncoprotein, gankyrin, isolated from hepatpmas, and its clinical applicationPrincipal Investigator

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Higashitsuji Hiroaki 東辻宏明

HIGASHITSUJI Hiroaki 東辻宏明