MATSUZAWA Mituhiro 松澤光洋

Researcher Number	60288082
External Links
Affiliation (based on the past Project Information) *help	2011 – 2013: 神奈川歯科大学, 歯学部, その他 2008 – 2010: Kanagawa Dental College, 歯学部, 講師 2007 – 2008: Kanagawa Dental College, Dentistry, Assistant professor 1997 – 2006: 神奈川歯科大学, 歯学部, 助手
Review Section/Research Field	Principal Investigator 矯正・小児・社会系歯学 / Orthodontic/Pediatric dentistry Except Principal Investigator Orthodontic/Pediatric dentistry / 矯正・小児・社会系歯学 / Periodontal dentistry
Keywords	Principal Investigator 歯根膜細胞 / 細胞分化 / IGF-I / 細胞増殖 / 乳歯歯根膜細胞 / 細胞接着・伸展因子 / 骨基質タンパク質 / 骨芽細胞 / 破骨細胞 / ECM … More Except Principal Investigator 骨シアロ蛋白質 / 転写制御 / Runx2 / アメロジェニン / 線維芽細胞 / 破歯細胞 / 破骨細胞 / fibroblast / osteoclast / vitamin D3 / RANKL / osteoprotegerin / M-CSF / セメント質形成細胞 / 固有歯槽骨由来骨芽細胞 / キメラ遺伝子 / 定量的RT-PCR分析 / 骨シアロ蛋白質(BSP) / 歯小嚢 / MARs / SATB2 / Ｒｕｎｘ２ / ＢＭＰ－２ / クロマチン / BMP2 / TGF-β1 / ヘルトウィッヒの上皮鞘(HERS)由来細胞 / 乳歯 / 歯根膜 / (1)乳歯 / (2)歯根膜 / (3)線維芽細胞 / (4)破歯細胞 / 生理的歯根吸収 / deciduous tooth / periodontal ligament / odontoclast / エナメル基質タンパク質 / 歯周組織再生 / ヒト歯根膜由来線維芽細胞(HPLF) / ラット骨髄由来細胞(RBMC) / 細胞接着因子 / 足場(スキャフォールド) / 細胞外基質タンパク質の発現 / 細胞遊走因子 / 歯根膜由来線維芽細胞 / ラット骨髄由来幹細胞 / ECMの遺伝子発現 / DNAチップ解析 / 細胞遊走活性 / 接着分子の遺伝子発現 / Enamel Matrix Proteins / Periodontal Tissue Regeneration / Human Periodontal Ligament Fibroblast(HPLF) / Rat Bone Marrow Cell(RBMC) / Cell Attachment Factors / Scaffold / Expression of Extracellular Matrix Protein / Cell Migration Factor / 乳歯歯根膜 / vitamin D_3 / periodontal Ligament of deciduous teeth / 歯学 / 骨芽細胞 / 分化 / 歯周組織 / Dentistry / Osteoblast / Differentiation / Periodontal Tissue Less

Molecular mechanisms of BSP gene transcription on cementblast
- Principal Investigator
  
  YAMAUCHI Masato
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Kanagawa Dental College
Basic study on osteoclastogenesis of human periodontal ligament derived cellsPrincipal Investigator
- Principal Investigator
  
  MATSUZAWA Mitsuhiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Kanagawa Dental College
Transcriptional regulation of BSP gene mediated by cementoblast like cell in vitro
- Principal Investigator
  
  YAMAUCHI Masato
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Kanagawa Dental College
Basic study on the effect of mastication for growth and development of dentition
- Principal Investigator
  
  KIMOTO Shigenari
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Kanagawa Dental College
Basic Research for Tissue Engineering of Periodontal Tissue Regeneration : Validity of Enamel Matrix Proteins and Periodontal Ligament Fibroblast Synthesized Proteins.
- Principal Investigator
  
  KAWASE Toshio
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Kanagawa Dental College
Molecular biological study on the physiologic function of periodntal ligament of human deciduous tooth
- Principal Investigator
  
  KIMOTO Shigenari
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Kanagawa Dental College
In Vitroにおけるヒト歯根膜組織由来細胞のcharacterizationPrincipal Investigator
- Principal Investigator
  
  松澤光洋
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Kanagawa Dental College
Cell biological study on physiological root resorption of deciduous teeth ; potentiality to support odontoclast differentiation on periodontal ligament fibroblasts derived from of human deciduous teeth
- Principal Investigator
  
  KIMOTO Shigenari
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Kanagawa Dental College
ヒト乳歯歯根膜細胞の増殖と分化に対するIGF-Iの影響に関する細胞生物学的研究Principal Investigator
- Principal Investigator
  
  松澤光洋
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Kanagawa Dental College

All 2009 2008 2007 2006 2005

All Journal Article Presentation

[Journal Article] アメロジェニンによる骨系細胞分化制御メカニズムの解析2009
- Author(s)
  松澤光洋
- Journal Title
  
  小児歯科学雑誌 47
  
  Pages: 539-549
- NAID
  10027488454
- Data Source
  KAKENHI-PROJECT-20592417
[Journal Article] Putative signaling of amelogenin utilizes the Wint/beta-catenin pathway2009
- Author(s)
  Matsuzawa M, Sheu TJ, Lee YJ, Chen M, Li TF, Holz JD, Puzas JE.
- Journal Title
  
  J periodontal Res. 44 (3)
  
  Pages: 289-96
- Data Source
  KAKENHI-PROJECT-19592370
[Journal Article] アメロジェニンによる骨系細胞分化制御メカニズムの解析2009
- Author(s)
  松澤光洋
- Journal Title
  
  小児歯科学雑誌 47巻
  
  Pages: 539-549
- NAID
  10027488454
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592417
[Journal Article] Putative signaling action of amelogenin utilizes the Wnt/β-catenin pathway2009
- Author(s)
  Mitsuhiro Matsuzawa, et al
- Journal Title
  
  J.Periodont. Res. 44
  
  Pages: 289-296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592417
[Journal Article] Putative signaling action of amelogenin utilizes the Wnt/β -catenin pathway.2009
- Author(s)
  Matsuzawa M, Sheu TJ, Lee YJ, Chen M, Li TF, Huang CT, Holz JD, Puzas JE
- Journal Title
  
  J Periodont Res 44巻
  
  Pages: 289-296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592417
[Journal Article] Putative signaling action of amelogenin utilizes the Wnt/β -catenin pathway2008
- Author(s)
  Matsuzawa M, Sheu T-J, Lee Y-J, Chen M, Li T-F, Huang CT, Holz J, Puzas JE
- Journal Title
  
  Journal of Periodontal Research (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17592152
[Journal Article] Putative signaling action of amelogenin utilizes the Wnt/β-catenin path way2008
- Author(s)
  Matsuzawa M, Sheu T-J, Lee Y-J, Chen M, Li T-F, Huang CT, Holz J, Puzas JE
- Journal Title
  
  Journal of Periodontal Research (in press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17592152
[Journal Article] Enviromental agents affects skeletal growth and development2007
- Author(s)
  Holtz JD, Sheu TJ, Drissi H, Matsuzawa M, Zuscik MJ, Puzas JE.
- Journal Title
  
  Birth Defects Res C Embryo Today. 81 (1)
  
  Pages: 41-50
- Data Source
  KAKENHI-PROJECT-19592370
[Journal Article] Environmental Agents Affect Skeletal Growth and Development2007
- Author(s)
  Holz JD, Sheu T-J, Drissi H, Matsuzawa M, Zuscik MJ, Puzas JE
- Journal Title
  
  Birth Defects Research vol.81
  
  Pages: 41-50
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17592152
[Journal Article] Environmental Agents Affect Skeletal Growth and Development2007
- Author(s)
  Holz JD, Sheu T-J, Drissi H, Matsuzawa M, Zuscik MJ, Puzas JE
- Journal Title
  
  Birth Defects Research 81
  
  Pages: 41-50
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17592152
[Presentation] Amelogenin(M180) showed high affinity to tissue inhibitor metaloprotease 2 (TIMP-2) and helped osteoblasts mineralization by inhibiting TIMP-2 activity.2009
- Author(s)
  松澤光洋
- Organizer
  ASBMR, 31^<st> Annual Meeting
- Place of Presentation
  Colorado, USA
- Data Source
  KAKENHI-PROJECT-20592417
[Presentation] アメロジェニンによる骨系細胞分化調節機構の解析2009
- Author(s)
  松澤光洋, 他
- Organizer
  第47回日本小児歯科学会大会
- Place of Presentation
  大阪大学(大阪)
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-20592417
[Presentation] アメロジェニンによる骨芽細胞分化調節機構の解析(第4報)破骨細胞分化誘導能について2009
- Author(s)
  松澤光洋
- Organizer
  第47回日本小児歯科学会大会
- Place of Presentation
  大阪
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-20592417
[Presentation] アメロジェニンによる骨芽細胞分化調節機構の解析(第5報)2009
- Author(s)
  松澤光洋
- Organizer
  第44回神奈川歯科大学学会総会
- Place of Presentation
  横須賀
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-20592417
[Presentation] Amelogenin activates the Wnt/β-catenin pathway2008
- Author(s)
  Matsuzawa M
- Organizer
  86^<th> General Session & Exhibition of the IADR
- Place of Presentation
  Toronto Canada
- Data Source
  KAKENHI-PROJECT-19592370
[Presentation] アメロジェニンによる骨芽細胞分化調節機構の解析(第4報)2008
- Author(s)
  松澤光洋
- Organizer
  第43回神奈川歯科大学学会総会
- Place of Presentation
  横須賀
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-20592417
[Presentation] アメロジェニンによる骨芽細胞分化調節機構の解析(第3報)-TIMP-2間相互作用について-2008
- Author(s)
  松澤光洋
- Organizer
  第46回日本小児歯科学会大会
- Place of Presentation
  大宮
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-20592417
[Presentation] Amelogenin activates the Wnt/β-catenin pathway.2008
- Author(s)
  松澤光洋
- Organizer
  86^<th> General Session and Exhibition of the IADR
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-20592417
[Presentation] アメロジェニンによる骨芽細胞分化機構の解析 (第4報)2008
- Author(s)
  松澤光洋
- Organizer
  第43回神奈川歯科大学総会
- Place of Presentation
  横須賀
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-19592370
[Presentation] アメロジェニンによる骨芽細胞分化調節機構の解析2007
- Author(s)
  松澤光洋, 室井剛史, 進士久明, 木本茂成, 川瀬俊夫, 黄嘉道, 許綜仁, Puzas JE
- Organizer
  第45回日本小児歯科学会大会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17592152
[Presentation] Analysis for regulatory mechanism of osteoblast differentiation by Amerogenin2007
- Author(s)
  Matsuzawa M, Muroi T, Shinji H, Kimoto S, Kawase T, Huang CT, Sheu T-J, Puzas JE
- Organizer
  45th General Assembly of the Japanese Society of Pediatric Dentistry
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17592152
[Presentation] Analysis for regulatory mechanism of osteoblast differentiation by Amelogenin2007
- Author(s)
  Matsuzawa M, Muroi T, Shinji H, Kimoto S, Kawase T, Huang CT, Sheu T-J, Puzas JE
- Organizer
  42th General Meeting of Kanagawa Odontological Society
- Place of Presentation
  Yokosuka
- Year and Date
  2007-12-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17592152
[Presentation] アメロジェニンによる骨芽細胞分化調節機構の解析(第2報)Wnt/β-cateninシグナル伝達系について2007
- Author(s)
  松澤光洋
- Organizer
  第45回日本小児歯科学会大会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2007-07-20
- Data Source
  KAKENHI-PROJECT-17592152
[Presentation] アメロジェニンによる骨芽細胞分化調節機構の解析(第3報)-Wnt/β-catenin シグナル伝達系について-2007
- Author(s)
  松澤光洋, 室井剛史, 進士久明, 木本茂成, 川瀬俊夫, 黄嘉道, 許綜仁, Puzas JE
- Organizer
  第42回神奈川歯科大学学会総会
- Place of Presentation
  横須賀
- Year and Date
  2007-12-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17592152
[Presentation] アメロジェニンによる骨芽細胞分化機構の解析 (第2報 Wint/β-catenin シグナル伝達系について)2007
- Author(s)
  松澤光洋
- Organizer
  第45回日本小児歯科学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19592370
[Presentation] アメロジェニンによる骨芽細胞分化機構の解析 (第3報 Wint/β-catenin シグナル伝達系について)2007
- Author(s)
  松澤光洋
- Organizer
  第42回神奈川歯科大学総会
- Place of Presentation
  横須賀
- Year and Date
  2007-12-08
- Data Source
  KAKENHI-PROJECT-19592370
[Presentation] アメロジェニンによる骨芽細胞分化制御機構の解析2006
- Author(s)
  松澤光洋, 木本茂成, 進士久明, 佐藤貞雄, 川瀬俊夫, 黄嘉道, 許綜仁, Puzas JE.
- Organizer
  第44回日本小児歯科学会大会
- Place of Presentation
  松本
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17592152
[Presentation] Analysis for regulatory mechanism of osteoblast differentiation by Amerogenin(second report)2006
- Author(s)
  Matsuzawa M, Kimoto S, Shinji H, Sato S, Kawase T, Huang CT, Sheu T-J, Puzas JE
- Organizer
  41th General Meeting of Kanagawa Odontological Society
- Place of Presentation
  Yokosuka
- Year and Date
  2006-12-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17592152
[Presentation] アメロジェニンによる骨芽細胞分化調節機構の解析(第2報)2006
- Author(s)
  松澤光洋, 木本茂成, 進士久明, 佐藤貞雄, 川瀬俊夫, 黄嘉道, 許綜仁, Puzas JE.
- Organizer
  第41回神奈川歯科大学学会・総会
- Place of Presentation
  横須賀
- Year and Date
  2006-12-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17592152
[Presentation] Analysis for regulatory mechanism of osteoblast differentiation by Amerogenin2006
- Author(s)
  Matsuzawa M, Kimoto S, Shinji H, Sato S, Kawase T, Huang CT, Sheu T-J, Puzas JE
- Organizer
  44th General Assembly of the Japanese Society of Pediatric Dentistry
- Place of Presentation
  Matsumoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17592152
[Presentation] リコンビナントアメロジェニンの骨芽細胞分化調節機構について2005
- Author(s)
  松澤光洋, 黄嘉道, 許綜仁, 木本茂成, 進士久明, 佐藤貞雄, 川瀬俊夫, Puzas J.E.
- Organizer
  第40回神奈川歯科大学学会・総会
- Place of Presentation
  横須賀
- Year and Date
  2005-12-03
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17592152
[Presentation] Regulatory mechanism of recombinant amerogenin on osteoblast differentiation2005
- Author(s)
  Matsuzawa M, Huang CT, Sheu T-J, Kimoto S, Shinji H, Sato S, Kawase T, Puzas JE
- Organizer
  40th General Meeting of Kanagawa Odontological Society
- Place of Presentation
  Yokosuka
- Year and Date
  2005-12-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17592152

1. KIMOTO Shigenari (90205013)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
2. KAWASE Toshio (30084784)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
3. SAITO Masahiro (40215562)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. YAMAUCHI Masato (30230311)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. NOZAKI Naohito (70222198)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. YOKOYAMA Mina (10386849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KUMASAKA Sumio (10161697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. UCHIMURA Noboru (80104454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SAITO Yoshiyuki (10277907)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. DEGUCHI Shinnji (60121018)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. FUJIHARA Tutomu (50084778)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. NEGISHI Hideyuki (60121026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 斎藤滋 (80084713)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MATSUZAWA Mituhiro 松澤 光洋

Research Projects

Research Products

Co-Researchers

Molecular mechanisms of BSP gene transcription on cementblast

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic study on osteoclastogenesis of human periodontal ligament derived cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Transcriptional regulation of BSP gene mediated by cementoblast like cell in vitro

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic study on the effect of mastication for growth and development of dentition

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic Research for Tissue Engineering of Periodontal Tissue Regeneration : Validity of Enamel Matrix Proteins and Periodontal Ligament Fibroblast Synthesized Proteins.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular biological study on the physiologic function of periodntal ligament of human deciduous tooth

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

In Vitroにおけるヒト歯根膜組織由来細胞のcharacterizationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cell biological study on physiological root resorption of deciduous teeth ; potentiality to support odontoclast differentiation on periodontal ligament fibroblasts derived from of human deciduous teeth

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒト乳歯歯根膜細胞の増殖と分化に対するIGF-Iの影響に関する細胞生物学的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] アメロジェニンによる骨系細胞分化制御メカニズムの解析2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Putative signaling of amelogenin utilizes the Wint/beta-catenin pathway2009

Author(s)

Journal Title

Data Source

[Journal Article] アメロジェニンによる骨系細胞分化制御メカニズムの解析2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Putative signaling action of amelogenin utilizes the Wnt/β-catenin pathway2009

Author(s)

Journal Title

Data Source

[Journal Article] Putative signaling action of amelogenin utilizes the Wnt/β -catenin pathway.2009

Author(s)

Journal Title

Data Source

MATSUZAWA Mituhiro 松澤光洋