Sadakane Yutaka 定金豊

… Alternative Names

SADAKANE Yutaka 定金豊

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Researcher Number	60293304
Other IDs
External Links
Affiliation (Current)	2025: 鈴鹿医療科学大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2016 – 2023: 鈴鹿医療科学大学, 薬学部, 教授 2011 – 2013: 鈴鹿医療科学大学, 薬学部, 教授 2008 – 2010: Kyushu University of Health and Welfare, 薬学部, 准教授 2004 – 2007: 九州保健福祉大学, 薬学部, 講師 2001 – 2003: 富山医科薬科大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Physical pharmacy / Drug development chemistry / Chemical biology / Chemical biology / Nerve anatomy/Neuropathology / 医薬分子機能学 / Biological Sciences Except Principal Investigator Environmental pharmacy / Chemistry related to living body / Bioorganic chemistry
Keywords	Principal Investigator ジアジリン / 光反応 / 光反応基 / コンフォメーション病 / バイオテクノロジー / 分析化学 / プロテオーム / DNA結合タンパク質 / 方法論開発 / 方法論の開発 … More / SELEX法 / トロンビン / S化DNA / パニング法 / 神経科学 / アミロイド / ペプチド結合タンパク質 / 糖鎖結合タンパク質 / ハイスループット / 光アフィニティーラベル / パンデミック / 光反応ユニット / カルベン / 提示ファージ / 電気泳動 / 分析科学 / アミノ酸 / 遺伝子工学 / コンファメーション病 / カルモジュリン / Dアミノ酸 / 光化学 / 修復酵素 / 加齢性疾患 / ファージ / 光 / アスパラギン酸残基 / アスパラギン残基 / 老化 / peptide polymerization / screening / panning / proteome / amyloid / antibody-displayed phage / diazirine / photoreaction / ペプチド多量化 / スクリーニング / パニング / 抗体提示ファージ / プロテーム / 質量分析 / ゲルシフトアッセイ / 薬学 / 糖鎖 / 開裂と閉環 / ペプチド合成 / アルツハイマー病 / 神経細胞 / アスパラギン酸 / ジケトピペラチン / 異性化 / アミロイドペプチド / 受容体発現系 / フォト・パニング / プロテオミクス / 不斉合成 / プロテオーム解析 … More Except Principal Investigator カルノシン / イメージング / 銅 / プリオン / プリオン病 / アルツハイマー病 / 小胞体ストレス / アポトーシス / カルシウム / 亜鉛 / 無機金属毒性 / 中毒学 / プロテオミクス / 脳血管性認知症 / コンフォメーション / 紫外線影響 / 光学異性体分析 / 蛋白質異常凝集 / 皮膚の光老化 / 加齢性疾患 / 紫外線 / ラセミ化 / 老化 / 白内障 / D-アミノ酸 / 蛋白質の異常凝集 / RT-PCR / 小胞体 / チャネル / 虚血性神経細胞死 / p8 / ペプチド / 糖鎖結合タンパク質 / プローブライブラリー / アビジン-ビオチン系 / カルモジュリン / レクチン / グライコミクス / アレイ化 / ジアジリン / 光アフィニティーラベル Less

Development of photochemical SELEX for efficient screening of DNA aptamers.Principal Investigator
- Principal Investigator
  
  定金豊
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Suzuka University of Medical Science
Efficient separation method for nucleic acid aptamers using photochemical techniquePrincipal Investigator
- Principal Investigator
  
  Sadakane Yutaka
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Suzuka University of Medical Science
Development of photochemical screening for aged proteins in brainPrincipal Investigator
- Principal Investigator
  
  Sadakane Yutaka
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Suzuka University of Medical Science
Development of photochemical cloning for DNA-binding proteinsPrincipal Investigator
- Principal Investigator
  
  SADAKANE Yutaka
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical biology
- Research Institution
  Suzuka University of Medical Science
Molecular mechanism of zinc-induced neurotoxicity : involvement of Ca and ER stress
- Principal Investigator
  
  KAWAHARA Masahiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Kyushu University of Health and Welfare
Mechanism of abnormal protein aggregation and the study of the repair enzyme.
- Principal Investigator
  
  FUJII Noriko
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Kyoto University
Development of the photochemical panning adapted to low affinity ligands and analysis of neural carbohydrates' functionsPrincipal Investigator
- Principal Investigator
  
  SADAKANE Yutaka
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical biology
- Research Institution
  Kyushu University of Health and Welfare
Involvement of calcium homeostasis in the apoptotic neuronal death induced by zinc
- Principal Investigator
  
  KAWAHARA Masahiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Kyushu University of Health and Welfare
Development of screening system for antibody-displayed phages by photo panning method : isolation of anti-amyloid antibodyPrincipal Investigator
- Principal Investigator
  
  SADAKANE Yutaka
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyushu University of Health and Welfare
アルツハイマーAβペプチドの新規自己開裂・閉環現象の解明と応用Principal Investigator
- Principal Investigator
  
  定金豊
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kyushu University of Health and Welfare
分子認識プロテオミクスを目的とする光キャプチャー法開発
- Principal Investigator
  
  畑中保丸
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Toyama Medical and Pharmaceutical University
フォト・パニング法による受容体タンパク質の機能解析Principal Investigator
- Principal Investigator
  
  定金豊
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Toyama Medical and Pharmaceutical University
受容体の提示発現系と光化学的パニング法の開発Principal Investigator
- Principal Investigator
  
  定金豊
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  Toyama Medical and Pharmaceutical University

[Book] Protective substances against zinc-induced neuronal death after ischemia : carnosine as a target for drug of vascular type of dementia. In Frontiers in CNS Drug Discovery2010
- Author(s)
  Kawahara M, Konoha K, Tetsuya N and Sadakane Y
- Publisher
  Bentham Science Publishers
- Data Source
  KAKENHI-PROJECT-21590145
[Book] Quantification of structural alterations of L-Asp and L-Asn residues in peptides related to neuronal disease by reversed-phase HPLC. In D-Amino Acids in chemistry, Life Sciences and Biotechnology2010
- Author(s)
  Sadakane Y., Konoha K., Kawahara M., Nakagomi K. Hans Bruckner and Noriko Fujii
- Data Source
  KAKENHI-PROJECT-21590145
[Book] 日本薬学会物理系薬学部会・分析化学担当教員会議編、認知症予防候補物質の探索と単離・構造決定、「薬学分析科学の最前線」2009
- Author(s)
  川原正博, 定金豊
- Total Pages
  185
- Publisher
  じほう
- Data Source
  KAKENHI-PROJECT-19590133
[Book] 認知症予防候補物質の探索と単離・構造決定、「薬学分析科学の最前線」、日本薬学会物理系薬学部会・分析化学担当教員会議編2009
- Author(s)
  川原正博、定金豊
- Publisher
  じほう
- Data Source
  KAKENHI-PROJECT-21590145
[Book] Chemical Genomics (分担著書:p199-214)2004
- Author(s)
  Y.Sadakane, Y.Hatanaka
- Total Pages
  357
- Publisher
  Marcel Dekker Inc., New York.
- Data Source
  KAKENHI-PROJECT-16650077
[Book] Multifunctional photoprobes for rapid protein identification : In "Chemical Genomics" (Eds. Darvas F., Guttman A., Dorman G.)2004
- Author(s)
  Sadakane Y., Hatanaka Y.
- Publisher
  Marcel Dekker Inc., New York
- Data Source
  KAKENHI-PROJECT-14658185
[Journal Article] Quantification of serine residue stereoinversion in a short peptide by reversed-phase high-performance liquid chromatography: analysis of mechanisms promoting serine stereoinversion2024
- Author(s)
  Sadakane Yutaka、Kobayashi Mizuki、Sano Mitsuteru、Morimoto Shota、Hagino Megumi
- Journal Title
  
  Analytical Sciences
  
  Volume: 40 Issue: 5 Pages: 925-934
- DOI
  10.1007/s44211-024-00543-5
- Data Source
  KAKENHI-PROJECT-23K06088
[Journal Article] Effect of amino acids present at the carboxyl end of succinimidyl residue on the rate constants for succinimidyl hydrolysis in small peptides2020
- Author(s)
  Sadakane Y, Senda S, Deguchi T, Tanaka A, Tsuruta H, Morimoto S
- Journal Title
  
  Biochim Biophys Acta Proteins Proteom .
  
  Volume: 1868 Issue: 11 Pages: 140496-140496
- DOI
  10.1016/j.bbapap.2020.140496
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07031
[Journal Article] Carnosine as a Possible Drug for Zinc-Induced Neurotoxicity and Vascular Dementia.2020
- Author(s)
  Kawahara M, Sadakane Y, Mizuno K, Kato-Negishi M, Tanaka KI.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 21 Issue: 7 Pages: 2570-2570
- DOI
  10.3390/ijms21072570
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06669, KAKENHI-PROJECT-19K07031, KAKENHI-PROJECT-17H03197
[Journal Article] Implications of Metal Binding and Asparagine Deamidation for Amyloid Formation.2018
- Author(s)
  Sadakane Y, Kawahara M.
- Journal Title
  
  Int J Mol Sci. 2018 Aug 19;19(8). pii: E2449. doi: 10.3390/ijms19082449.
  
  Volume: 19 Issue: 8 Pages: 1-23
- DOI
  10.3390/ijms19082449
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06669, KAKENHI-PROJECT-16K08207
[Journal Article] Photoreactive biomacromolecules: Installation of photoreactive units and applications for analyzing biological interfaces2017
- Author(s)
  Yutaka Sadakane, Isao Ohtsuka, and Yasumaru Hatanaka
- Journal Title
  
  Photoaffinity Labeling for Structural Probing within Protein
  
  Volume: 2017 Pages: 129-157
- DOI
  10.1007/978-4-431-56569-7_7
- ISBN
  9784431565680, 9784431565697
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08207
[Journal Article] タンパク質中のアミノ酸レベルの自発的構造変化の分析と意義2017
- Author(s)
  定金　豊
- Journal Title
  
  ぶんせき
  
  Volume: 2017年7号 Pages: 305-311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08207
[Journal Article] Photoaffinity electrophoretic mobility shift assay using photoreactive DNA bearing 3-trifluoromethyl-3-phenyldiazirine in its phosphate backbone.2016
- Author(s)
  Yutaka Sadakane, Yasumaru Hatanaka
- Journal Title
  
  Anal. Biochem.
  
  Volume: 506 Pages: 1-7
- DOI
  10.1016/j.ab.2016.04.016
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K08207
[Journal Article] 市販の酵素を組合せたLC-MSでのアミノ酸残基の構造的異性化の迅速な分析法2016
- Author(s)
  定金　豊
- Journal Title
  
  ぶんせき
  
  Volume: 2016－1 Pages: 30-30
- Data Source
  KAKENHI-PROJECT-16K08207
[Journal Article] Disruption of zinc homeostasis and the pathogenesis of senile dementia2014
- Author(s)
  M. Kawahara, D. Mizuno, H. Koyama, K. Konoha, S. Ohkawara, Y. Sadakane
- Journal Title
  
  Metallomics
  
  Volume: 6 Issue: 2 Pages: 209-216
- DOI
  10.1039/c3mt00257h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510286, KAKENHI-PROJECT-24500527
[Journal Article] Disruption of zinc homeostasis and the pathogenesis of senile dementia2014
- Author(s)
  M. Kawahara, D. Mizuno, H. Koyama, K. Konoha, S. Ohkawara,, Y. Sadakane
- Journal Title
  
  Metallomics
  
  Volume: 6 Pages: 209-219
- Data Source
  KAKENHI-PROJECT-23510286
[Journal Article] D-Histidine and L-histidine attenuate zinc-induced neuronal death in GT1-7 cells2013
- Author(s)
  M. Kawahara, Y. Sadakane, H. Koyama, K. Konoha, S. Ohkawara
- Journal Title
  
  Metallomics
  
  Volume: 5 Issue: 5 Pages: 453-460
- DOI
  10.1039/c3mt20264j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510286
[Journal Article] Experimental conditions for analyzing carbohydrate-binding protein using photoreactive lactose ligand prepared with AffiLight CHO2012
- Author(s)
  Y. Sadakane, M. Yamazi, I. Otsuka
- Journal Title
  
  Photomedicine and Photobiology
  
  Volume: 34 Pages: 37-38
- Data Source
  KAKENHI-PROJECT-23510286
[Journal Article] Zinc neurotoxicity and the pathogenesis of vascular-type dementia : Involvement of calcium dyshomeostasis and carnosine2012
- Author(s)
  Koyama H, Konoha K, Sadakane Y, Ohkawara S, Kawahara M
- Journal Title
  
  J.Clin Toxicol.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590145
[Journal Article] Zinc neurotoxicity and the pathogenesis of vascular-type dementia : Involvement of calcium dyshomeostasis and carnosine2012
- Author(s)
  Koyama H, Konoha K, Sadakane Y, Ohkawara S, and Kawahara M
- Journal Title
  
  J. Clin Toxicol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590145
[Journal Article] The effect of the structural differences in the reducing terminus of sugars on the binding affinity of carbohydrates and proteins analyzed using photoaffinity labeling2011
- Author(s)
  I. Ohtsuka, Y. Sadakane, M. Higuchi, N. Hada, J. Hada, N. Kakiuchi, A. Sakushima
- Journal Title
  
  Bioorg Med. Chem.
  
  Volume: 19 Pages: 894-899
- Data Source
  KAKENHI-PROJECT-23510286
[Journal Article] Determination of rate constants for beta-linkage isomerization of three specific aspartyl residues in recombinant human alpha A-crystallin protein by reversed-phase HPLC2011
- Author(s)
  Y. Sadakane, N. Fujii, K. Nakagomi
- Journal Title
  
  J Chromatogr. B.
  
  Volume: 879 Pages: 3240-3246
- Data Source
  KAKENHI-PROJECT-23510286
[Journal Article] Determination of rate constants for beta-linkage isomerization of three specific aspartyl residues in recombinant human alpha A-crystallin protein by reversed-phase HPLC2011
- Author(s)
  Yutaka Sadakane, Noriko Fujii, Kazuya Nakagomi
- Journal Title
  
  J Chromatogr.B (in press)
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] Zinc, copper, and carnosine attenuate neurotoxicity of prion fragment PrP106-1262011
- Author(s)
  Kawahara M., Koyama H., Nagata T., Sadakane Y.
- Journal Title
  
  Metallomics (in press)
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] Determination of rate constants for beta-linkage isomerization of three specific as partyl residues in recombinant human alpha A-crystallin protein by reversed-phase HPLC2011
- Author(s)
  Sadakane Y.
- Journal Title
  
  J Chromatogr.B
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] A basic study of photochemical panning for ligands with lower binding affinity2011
- Author(s)
  Sadakane Y.
- Journal Title
  
  Photomedicine and Photobiology
  
  Volume: 32 Pages: 24-25
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] Membrane incorporation, channel formation, and disruption of calcium homeostasis by Alzheimer's s-amyloid protein2011
- Author(s)
  Kawahara M., Ohtsuka I., Yokoyama S., Kato-Negishi M. and Sadakane Y
- Journal Title
  
  Int. J. Alzheimer Dis.
  
  Pages: 304583-304583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590145
[Journal Article] Membrane incorporation, channel formation, and disruption of calcium homeostasis by Alzheimer's β-amyloid protein2011
- Author(s)
  Kawahara M., Ohtsuka I., Yokoyama S., Kato-Negishi M., Sadakane Y.
- Journal Title
  
  Int.J.Alzheimer Dis.
  
  Volume: 2011 Pages: 304583-304583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590145
[Journal Article] Determination of rate constants for beta-linkage isomerization of three specific aspartyl residues in recombinant human alpha A-crystallin protein by reversed-phase HPLC2011
- Author(s)
  Y.Sadakane, N.Fujii, K.Nakagomi
- Journal Title
  
  J.Chromatogr.B
  
  Volume: 879 Issue: 29 Pages: 3240-3246
- DOI
  10.1016/j.jchromb.2011.03.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350077
[Journal Article] Zinc, copper, and carnosine attenuate neurotoxicity of prion fragment PrP106-1262011
- Author(s)
  Kawahara M, Koyama H., Nagata T., Sadakane Y.
- Journal Title
  
  Metallomics
  
  Volume: 3 Pages: 726-734
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590145
[Journal Article] Effects of trace metals on the conformational changes of amyloidogenic proteins and their neurotoxicity2011
- Author(s)
  M. Kawahara, H. Koyama, Y. Sadakane
- Journal Title
  
  Biomed. Res.Trace Elements
  
  Volume: 22 Pages: 7-14
- NAID
  10028117958
- Data Source
  KAKENHI-PROJECT-23510286
[Journal Article] A basic study of photochemical panning for ligands with lower binding affinity2011
- Author(s)
  Y.sadakane, I.Otsuka, K
- Journal Title
  
  Photomedicine and Photobiology 32(in press)
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] アスパラギンおよびアスパラギン酸残基の構造的変化解析:神経疾患機構との繋がりを求めて2011
- Author(s)
  定金豊
- Journal Title
  
  KURRI-KR
  
  Volume: 164 Pages: 15-19
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] アミロイド形成蛋白の高次構造変化と神経毒性に及ぼす金属の影響2011
- Author(s)
  川原正博、小山裕也、定金豊
- Journal Title
  
  Biomed. Res. Trace Elements
  
  Volume: 22 Pages: 7-14
- NAID
  10028117958
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590145
[Journal Article] アミロイド形成蛋白の高次構造変化と神経毒性に及ぼす金属の影響2011
- Author(s)
  川原正博、小山裕也、定金豊
- Journal Title
  
  Biomed.Res.Trace Elements
  
  Volume: 28 Pages: 49-53
- NAID
  10028117958
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590145
[Journal Article] The effect of the structural differences in the reducing terminus of sugars on the binding affinity of carbohydrates and proteins analyzed using photoaffinity labeling.2011
- Author(s)
  Isao Ohtsuka, Yutaka Sadakane, Mari Higuchi, Noriyasu Hada, Junko Hada, Nobuko Kakiuchi, Akiyo Sakushima
- Journal Title
  
  Bioorg Med. Chem.
  
  Volume: 19 Issue: 2 Pages: 894-899
- DOI
  10.1016/j.bmc.2010.11.067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510286
[Journal Article] アスパラギンおよびアスパラギン酸残基の構造的変化解析2011
- Author(s)
  定金豊
- Journal Title
  
  神経疾患機構との繋がりを求めて KURRI-KR-164
  
  Pages: 15-19
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] Effect of the binding affinity of carbohydrates and proteins by the structural difference of the reducing terminal of sugar using photoaffinity labeling.2011
- Author(s)
  Isao Ohtsuka, Yutaka Sadakane, Mari Higuchi, Noriyasu Hada, Junko Hada, Nobuko Kakiuchi, Akiyo Sakushima
- Journal Title
  
  Bioorg Med.Chem. 19
  
  Pages: 894-899
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] Membrane incorporation, channel formation, and disruption of calcium homeostasis by Alzheimer's beta-amyloid protein.2011
- Author(s)
  Masahiro Kawahara, Isao Ohtsuka, Shoko Yokoyama, Midori Kato-Negishi, Yutaka Sadakane
- Journal Title
  
  International Journal of Alzheimer's Disease. 2011,Article ID 304583 17
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] Differentiation and semiquantitative analysis of an isoaspartic acid in human α-crystallin by post source decay on curved field reflectron.2010
- Author(s)
  Yamazaki Y, Fujii N, Sadakane Y and FujiiN.
- Journal Title
  
  Anal. Chem.
  
  Volume: 82 Pages: 6384-6394
- Data Source
  KAKENHI-PROJECT-20350077
[Journal Article] Ligand structure for photoaffinity labeling of carbohydrate-binding protein2010
- Author(s)
  Sadakane Y
- Journal Title
  
  Photomedicine and Photobiology 31
  
  Pages: 9-10
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] Preparation of recombinant Asp-isomerized crystalline and analysis of the effects of Asp alternation on protein function and structure using radiation.2010
- Author(s)
  Sadakane Y., Fujii N
- Journal Title
  
  KURRI Prog. Rep 2008
  
  Pages: 6-5
- Data Source
  KAKENHI-PROJECT-21590145
[Journal Article] Ligand structure for photoaffinity labeling of carbohydrate-binding protein.2010
- Author(s)
  Sadakane Y, Otsuka I, Konoha K, Koyama H, Kawahara M, Hatanaka Y
- Journal Title
  
  Photomedicine and Photobiology 31(In press)
- Data Source
  KAKENHI-PROJECT-21590145
[Journal Article] Ligand structure for photoaffinity labeling of carbohydrate-binding protein2010
- Author(s)
  Sadakane Y, Otsuka I, Konoha K, Koyama H, Kawahara M, Hatanaka Y
- Journal Title
  
  Photomedicine and Photobiology
  
  Volume: 31 Pages: 9-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590145
[Journal Article] Quantification of structural alterations of L-Asp and L-Asn residues in peptides related to neuronal disease by reversed-phase HPLC.2010
- Author(s)
  Sadakane Y
- Journal Title
  
  Chem. & Biodivers. 7(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] Effects of UV-B irradiation on the stability of amino acids and peptides.2010
- Author(s)
  Sadakane Y, Fukuhara T, Kawahara M, Nakagomi K
- Journal Title
  
  J.KUHW 11
  
  Pages: 147-152
- NAID
  110007577967
- Data Source
  KAKENHI-PROJECT-21590145
[Journal Article]2010
- Author(s)
  Kawahara M, Konoha K, Nagata T, Sadakane Y
- Journal Title
  
  Frontiers in CNS Drug Discovery(Bentham Science Publishers)
  
  Pages: 21-30
- Data Source
  KAKENHI-PROJECT-21590145
[Journal Article] Quantification of structural alterations of L-Asp and L-Asn residues in peptides related to neuronal disease by reversed-phase HPLC2010
- Author(s)
  Sadakane Y, Konoha K., Kawahara M., Nakagomi K.
- Journal Title
  
  Chem. & Biodivers
  
  Volume: 7 Pages: 1371-1379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590145
[Journal Article] Quantification of structural alterations of L-Asp and L-Asn residues in peptides related to neuronal disease by reversed-phase HPLC2010
- Author(s)
  Sadakane Y, Konoha K., Kawahara M., Nakagomi K
- Journal Title
  
  Chem. & Biodivers (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590145
[Journal Article] Differentiation and semiquantitative analysis of an isoaspartic acid in human alpha-Crystallin by postsource decay in a curved field reflectron.2010
- Author(s)
  Yamazaki Y, Fujii N, Sadakane Y, Fujii N
- Journal Title
  
  Anal.Chem. 82
  
  Pages: 6384-6394
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] Effects of UV-B irradiation on the stability of amino acids and peptides2010
- Author(s)
  Sadakane Y
- Journal Title
  
  J.KUHW 11
  
  Pages: 147-152
- NAID
  110007577967
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] Analysis of structural alternation of L-Asp and L-Asn residures in the peptides related to neuronal conformation disease2010
- Author(s)
  Sadakane Y., Konoha K., Kawahara M
- Journal Title
  
  KURRI-KR 148
  
  Pages: 1-5
- Data Source
  KAKENHI-PROJECT-21590145
[Journal Article] Effects of UV-B irradiation on the stability of amino acids and peptides.2010
- Author(s)
  Sadakane Y, Fukuhara T, Kawahara M, Nakagomi K
- Journal Title
  
  J.KUHW
  
  Volume: 11 Pages: 147-152
- NAID
  110007577967
- Data Source
  KAKENHI-PROJECT-21590145
[Journal Article] Analysis of structural alternations of L-Asp and L-Asn residues in peptides related to neuronal conformational disease.2010
- Author(s)
  Sadakane Y.
- Journal Title
  
  KURRI-KR
  
  Volume: 155 Pages: 1-5
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] Quantification of structural alterations of L-Asp and L-Asn residues in peptides related to neuronal disease by reversed-phase HPLC2010
- Author(s)
  Sadakane Y, Konoha K., Kawahara M., Nakagomi K.
- Journal Title
  
  Chem.& Biodivers
  
  Volume: 7 Pages: 1371-1379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590145
[Journal Article] Quantification of structural alterations of L-Asp and L-Asn residues in peptides related to neuronal disease by reversed-phase HPLC.2010
- Author(s)
  Y.Sadakane, K.Konoha, M.Kawahara, K.Nakagomi
- Journal Title
  
  Chem.& Biodivers. 7
  
  Pages: 1371-1379
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] Differentiarion and semiquantitative analysis of an isoaspartic acid in humana α-crystallin by post source decay on curved field reflectron.2010
- Author(s)
  Yamazaki Y, Fujii N, Sadakane Y, Fuiii N.
- Journal Title
  
  Anal.Chem. 82
  
  Pages: 6384-6394
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350077
[Journal Article] Effects of UV-B irradiation on the stability of amino acids and peptides2010
- Author(s)
  Sadakane Y, Fukuhara T, Kawahara M, Nakagomi K
- Journal Title
  
  J. KUHW
  
  Volume: 11 Pages: 147-152
- NAID
  110007577967
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590145
[Journal Article] Quantification of structural alterations of L-Asp and L-Asn residues in peptides related to neuronal disease by reversed-phase HPLC2010
- Author(s)
  Sadakane Y.
- Journal Title
  
  Chem.& Biodivers
  
  Volume: 7 Pages: 1371-1379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] Ligand structure for photoaffinity labeling of carbohydrate-binding protein.2009
- Author(s)
  Y.Sadakane, I.Otsuka, K.Konoha, H.Koyama, M.Kawahara, Y.Hatanaka
- Journal Title
  
  Photomedicine and Photobiology 31
  
  Pages: 9-10
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] Analysis of structural alternation of L-Asp and L-Asn residures in the peptides related to neuronal conformation disease2009
- Author(s)
  Sadakane Y., Konoha K., Kawahara M.
- Journal Title
  
  KURRI-KR
  
  Volume: 148 Pages: 1-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590145
[Journal Article] Analysis of structural alternation of L-Asp and L-Asn residures in the peptides related to neuronal conformation disease.2009
- Author(s)
  Sadakane Y
- Journal Title
  
  KURRI-KR-148 148
  
  Pages: 1-5
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] Calcium dyshomeostasis andneurotoxicity of Alzheimer's beta-amyloidprotein. Expert Rev.2009
- Author(s)
  Kawahara M, Negishi-Kato M, Sadakane Y
- Journal Title
  
  Neurother 9
  
  Pages: 681-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590133
[Journal Article] Preparation of recombinant Asp-isomerized crystalline and analysis of the effects of Asp alternation on protein. function and structure.2009
- Author(s)
  Sadakane Y.
- Journal Title
  
  KURRI Prog.Rep. 2008
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] Calcium dyshomeostasis and neurotoxicity of Alzheimer's beta-amyloid protein.2009
- Author(s)
  Kawahara M, Negishi-Kato M, Sadakane Y
- Journal Title
  
  Expert Rev Neurother 9
  
  Pages: 681-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590133
[Journal Article] Calcium dyshomeostasis and neurotoxicity of Alzheimer's beta-amyloid protein.2009
- Author(s)
  Kawahara M, Negishi-Kato M, Sadakane Y.
- Journal Title
  
  Expert Rev Neurother. 9
  
  Pages: 681-693
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] Calcium dyshomeostasis and neurotoxicity of Alzheimer's beta-amyloid protein2009
- Author(s)
  Kawahara M. Negishi-Kato M, Sadakane Y.
- Journal Title
  
  Expert Rev Neurother
  
  Volume: 9 Pages: 681-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590145
[Journal Article] Calcium dyshomeostasis and neurotoxicity of Alzheimer's beta-amyloid protein.2009
- Author(s)
  Kawahara M., Negishi-Kato M, Sadakane Y
- Journal Title
  
  Expert Rev Neurother 9
  
  Pages: 681-693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590145
[Journal Article] Development of new method for molecular biology using the photophore, diazirine.2008
- Author(s)
  Y.Sadakane, Y.Hatanaka
- Journal Title
  
  YAKUGAKU ZASSHI 128
  
  Pages: 1615-1622
- NAID
  110006991376
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] Improvement of screening for protective substances against zinc-induced neuronal cell death2008
- Author(s)
  Sadakane Y, Konoha K, Nagata T, Kawahara M
- Journal Title
  
  Trace Nutrient Res 25
  
  Pages: 59-63
- NAID
  40016413893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590133
[Journal Article] Development of new method for molecular biology using the photophore, diazirine.2008
- Author(s)
  Y. Sadakane, 他
- Journal Title
  
  YAKUGAKU ZASSHI 128
  
  Pages: 1615-1622
- NAID
  110006991376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] Improvement of screening for protective substances against zinc-induced neuronal cell death.2008
- Author(s)
  Y.Sadakane, K.Konoha, T.Nagata, M.Kawahara
- Journal Title
  
  Trace Nutrients Res. 25
  
  Pages: 41-45
- NAID
  40016413893
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] Improvement of screening for protective substances against zinc-induced neuronal cell death.2008
- Author(s)
  Y. Sadakane, 他
- Journal Title
  
  Trace Nutrient Res. 25
  
  Pages: 59-63
- NAID
  40016413893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] Ten-minute purification of PCR products by continuous elution electrophoresis.2008
- Author(s)
  Y. Sadakane, 他
- Journal Title
  
  Anal. Biochem. 381
  
  Pages: 157-159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] On the frontier of analytical science by young scientist-Detection and utilization of biomolecules-2008
- Author(s)
  Y.Sadakane, M.Tsunoda
- Journal Title
  
  YAKUGAKU ZASSHI 128
  
  Pages: 1587-1588
- NAID
  110006991372
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] Improvement of screening for protective substances against zinc-induced neuronal cell death.2008
- Author(s)
  Sadakane Y, Konoha K, Nagata T, Kawahara M
- Journal Title
  
  Trace Nutrient Res 25
  
  Pages: 59-63
- NAID
  40016413893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590133
[Journal Article] Differential rate constants of racemization of aspartyl and asparaginyl residues in human alpha A-crvstallin mutants.2008
- Author(s)
  Nakamura T., Sakai M., Sadakane Y., Haga T., Goto Y., Kinouchi T., Saito T., Fujii
- Journal Title
  
  Biochim. Biophys. Acta 1784
  
  Pages: 1122-1199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350077
[Journal Article] Protective substances against zinc-induced neuronal death after ischemia : camosine a target for drug of vascular type of dementia.2007
- Author(s)
  M. Kawahara, K. Konoha, T. Nagata, Y. Sadakane
- Journal Title
  
  Recent Patents on CNS Drug Discovery, (with peer review.) 2
  
  Pages: 145-149
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Neurotoxicity of zinc:the involvement of calcium homeostasis and carnosine2007
- Author(s)
  M.Kawahara, K.Konoha, Y.Sadakane
- Journal Title
  
  Biomed Res Trace Elements 18
  
  Pages: 26-34
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Protective activity of the extracts from Japanese eel(Anguilla japonica) against zinc-induced neuronal cell death : Carnosine and an unknown substance.2007
- Author(s)
  Y. Sadakane, K. Konoha, T. Nagata, M. Kawahara
- Journal Title
  
  Trace Nutrient Res.(with peer review.) 24
  
  Pages: 1-4
- NAID
  40015808263
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Aluminum and human health:its intake,bioavailability and neurotoxicity2007
- Author(s)
  M.Kawahara, K.Konoha, T.Nagata, Y.Sadakane
- Journal Title
  
  Biomed.Res.Trace Elements 18
  
  Pages: 111-120
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Endeavors to make the photophore,diazirine easy to use2007
- Author(s)
  Y.Sadakane
- Journal Title
  
  YAKUGAKU ZASSHI 127
  
  Pages: 1693-1699
- NAID
  110006402953
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Protective activity of the extracts from Japanese eel(Anguilla japonica)against zinc-induced neuronal cell death:Carnosine and an unknown substance2007
- Author(s)
  Sadakane Y., Konoha K., Nagata T., Kawahara M
- Journal Title
  
  Trace Nutrient Res. 24
  
  Pages: 111-120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Neurotoxicity of aluminum hydroxyl polymer on primary cultured neurons of rat cerebral cortex2007
- Author(s)
  Konoha K, Nagata T, Sadakane Y, Kawahara M
- Journal Title
  
  Biomed.Res.Trace Elements 18
  
  Pages: 393-397
- NAID
  10021097781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Endeavors to make the photophore, diazirine easy to use.2007
- Author(s)
  Y. Sadakane
- Journal Title
  
  YAKUGAKU ZASSHJ(with peer review.) 127
  
  Pages: 1693-1699
- NAID
  110006402953
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Aluminum and human health: its intake, bioavailability and neurotoxicity2007
- Author(s)
  Kawahara M., Konoha K., Nagata T., Sadakane Y.
- Journal Title
  
  Biomed. Res. Trace Elements 18
  
  Pages: 111-120
- NAID
  130004456835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590133
[Journal Article] ヒトタンパク質アミノ酸配列中に潜在する生物活性ペプチド2007
- Author(s)
  中込和哉, 定金豊
- Journal Title
  
  ぶんせき 2007-2
  
  Pages: 66-73
- NAID
  10018521643
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Protective activity of the extracts from Japanese eel(Anguilla japonica)against zinc-induced neuronal cell death:Carnosine and an unknown substance2007
- Author(s)
  Y.Sadakane, K.Konoha, T.Nagata, M.Kawahara
- Journal Title
  
  Trace Nutrient Res. 24
  
  Pages: 1-4
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Age related changes of aipha-crystallin aggregate in human lens.2007
- Author(s)
  N. Fujii, Y. Shimmyo, M. Sakai, Y. Sadakane, T. Nakamura, Y. Morimoto, T. Kinouchi, Y. Goto, K. Lampi
- Journal Title
  
  Amino acids, (with peer review.) 32
  
  Pages: 87-94
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Neurotoxicity of aluminum hydroxyl polymer on primary cultured neurons of rat cerebral cortex2007
- Author(s)
  K.Konoha, T.Nagata, Y.Sadakane, M.Kawahara
- Journal Title
  
  Biomed.Res.Trace Elements 18
  
  Pages: 393-397
- NAID
  10021097781
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Aluminum and human health : its intake, bioavailability and neurotoxicity.2007
- Author(s)
  M. Kawahara, K. Konoha, T. Nagata, Y. Sadakane
- Journal Title
  
  Biomed. Res. Trace Elements, (with peer review.) 18
  
  Pages: 111-120
- NAID
  130004456835
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Protective substances against zinc-induced neuronal death after ischemia:carnosine a target for drug of vascular type of dementia2007
- Author(s)
  Kawahara M., Konoha K., Nagata T., Sadakane Y
- Journal Title
  
  Recent Patents on CNS Drsicovery 2
  
  Pages: 145-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590133
[Journal Article] Neurotoxicity of zinc : the involvement of calcium homeostasis and camosine.2007
- Author(s)
  M. Kawahara, K. Konoha, Y. Sadakane
- Journal Title
  
  Biomed. Res. Trace Elements, (with peer review.) 18
  
  Pages: 26-34
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Differential susceptibility of alpha A-and alpha B-crystallin to gammaray irradiation.2007
- Author(s)
  N. Fujii, T. Nakamura, Y. Sadakane, T. Saito, N. Fujii
- Journal Title
  
  BBA-Proteins and Proteomics 1774
  
  Pages: 345-350
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Bioactive peptides derived from amino acids sequences in human proteins2007
- Author(s)
  K. Nakagomi, Y. Sadakane
- Journal Title
  
  Bunseki, (with peer review) 2
  
  Pages: 66-73
- NAID
  10018521643
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Neurotoxicity of aluminum hydroxyl polymer on primary cultured neurons of rat cerebral cortex2007
- Author(s)
  Konoha K, Nagata T, Sadakane Y, Kawahara M
- Journal Title
  
  Biomed. Res. Trace Elements 18
  
  Pages: 395-399
- NAID
  10021097781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590133
[Journal Article] Neurotoxicity of aluminum hydroxyl polymer on primary cultured neurons of rat cerebral cortex2007
- Author(s)
  Konoha K, Nagata T, Sadakane Y, Kawahara M
- Journal Title
  
  Biomed.Res.Trace Elements 18
  
  Pages: 395-399
- NAID
  10021097781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590133
[Journal Article] Neurotoxicity of zinc: the involvement of calcium homeostasis and carnosine2007
- Author(s)
  Kawahara M., Konoha K., Sadakane Y.
- Journal Title
  
  Biomed. Res. Trace Elements 18
  
  Pages: 26-34
- NAID
  10018910865
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590133
[Journal Article] Aluminum and human health:its intake,bioavailability and neurotoxicity2007
- Author(s)
  Kawahara M., Konoha K., Nagata T., Sadakane Y.
- Journal Title
  
  Biomed.Res.Trace Elements 18
  
  Pages: 111-120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590133
[Journal Article] Protective substances against zinc-induced neuronal death after ischemia: carnosine a target for drug of vascular type of dementia2007
- Author(s)
  Kawahara M., Konoha K., Nagata T., Sadakane Y.
- Journal Title
  
  Recent Patents on CNS Drug Discovery 2
  
  Pages: 145-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590133
[Journal Article] Protective substances against zinc-induced neuronal death after ischemia:carnosine a target for drug of vascular type of dementia2007
- Author(s)
  M.Kawahara, K.Konoha, T.Nagata, Y.Sadakane
- Journal Title
  
  Recent Patents on CNS Drug Discovery 2
  
  Pages: 145-149
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Protective activity of the extracts from Japanese eel(Anguilla japonica)against zinc-induced neuronal cell death:Carnosine and an unknown substance2007
- Author(s)
  Sadakane Y., Konoha K., Nagata T., Kawahara M
- Journal Title
  
  Trace Nutrient Res 24
  
  Pages: 98-105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590133
[Journal Article] Protective activity of the extracts from Japanese eel (Anguilla japonica) against zinc-induced neuronal cell death: Carnosine and an unknown substance.2007
- Author(s)
  Sadakane Y., Konoha K., Nagata T., Kawahara M
- Journal Title
  
  Trace Nutrient Res. 24
  
  Pages: 98-105
- NAID
  40015808263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590133
[Journal Article] Neurotoxicity of zinc:the involvement of calcium homeostasis and carnosine2007
- Author(s)
  Kawahara M., Konoha K., Sadakane Y.
- Journal Title
  
  Biomed.Res.Trace Elements 18
  
  Pages: 26-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590133
[Journal Article] Differential susceptibility of alpha A-and alpha B-crystallin to gamma-ray irradiation2007
- Author(s)
  N.Fujii, T.Nakamura, Y.Sadakane, T.Saito, N.Fujii
- Journal Title
  
  BBA-Proteins and Proteomics 1774
  
  Pages: 345-350
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Age related changes of alpha-crystallin aggregate in human lens2007
- Author(s)
  N.Fujii, Y.Shimmyo, M.Sakai, Y.Sadakane, T.Nakamura, Y.Morimoto, T.Kinouchi, Y.Goto, K.Lampi.
- Journal Title
  
  Amino acids 32
  
  Pages: 87-94
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Neurotoxicity of aluminum hydroxyl polymer on primary cultured neurons of rat cerebral cortex.2007
- Author(s)
  K. Konoha, T. Nagata, Y. Sadakane, M. Kawahara
- Journal Title
  
  Biomed. Res. Trace Elements, (with peer review.) 18
  
  Pages: 393-397
- NAID
  10021097781
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Endeavors to make the photophore,diazirine easy to use2007
- Author(s)
  Y.sadakane
- Journal Title
  
  YAKUGAKU ZASSHI 127
  
  Pages: 1693-1699
- NAID
  110006402953
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Photoaffinity labeling of opioid-binding cell-adhesion molecule(OBCAM) by phenyldiazirine-integrated ligand.2006
- Author(s)
  Y.sadakane, E.Kitamoto, T.Tomohiro, K.Konoha, M.Kawahara, Y.Hatanaka
- Journal Title
  
  J.KUHW 8
  
  Pages: 179-185
- NAID
  110006407510
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Analysis of Structural Alternations of L-Asp and L-Asn Residues in Peptides Related to Neuronal Disease.2006
- Author(s)
  Y. Sadakane, S. Kumamoto, K. Konoha, M. Kawahara, K. Nakagomi
- Journal Title
  
  Peptide Sciences.(with peer review.) 43
  
  Pages: 284-284
- NAID
  10020529985
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Photochemical fishing approaches for identifying target proteins and elucidating the structure of a ligand-binding region using carbene-generating photoreactive probes2006
- Author(s)
  Y.Sadakane, Y.Hatanaka
- Journal Title
  
  Anal.Sci. 22
  
  Pages: 209-218
- NAID
  10017246234
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Hatanaka : Phenyldiazirine unit for converting peptides, proteins, DNAs, and sugars to photoaffinity ligands2006
- Author(s)
  Y. Sadakane, M. Kaneda, H. Nakashima, T. Tomohiro, K. Konoha, M. Kawahara, Y. Hatanaka
- Journal Title
  
  Photomedicine and Photobiology(without peer review.) 28
  
  Pages: 11-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Carnosine protects GT1-7 cell against zinc-induced neurotoxicity:a possible candidate for treatment for vascular type of dementia2006
- Author(s)
  K.Konoha, Y.Sadakane, M.Kawahara
- Journal Title
  
  Trace Nutrients Research 23
  
  Pages: 1-8
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Isolation of novel cathepsin B inhibitory peptides from enzymatic hydrolysates of human proteins2006
- Author(s)
  H.Koyama;M.Yasuda, K.Mawatari, K.Kaneko, Y.Sadakane, Y.Hatanaka, K.Nakagomi
- Journal Title
  
  Peptide Sciences 43
  
  Pages: 313-314
- NAID
  10020530123
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Zinc neurotoxicity and its role in neurodegenerative diseases2006
- Author(s)
  K. Konoha, Y. Sadakane, M. Kawahara
- Journal Title
  
  J. Health Sd.(with peer review.) 52
  
  Pages: 1-8
- NAID
  110006163207
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Analysis of Structural Alternations of L-Asp and L-Asn Residues in Peptides Related to Neuronal Disease2006
- Author(s)
  Y.Sadakane, S.Kumamoto, K.Konoha, M.Kawahara, K.Nakagomi
- Journal Title
  
  Peptide Sciences 43
  
  Pages: 284-284
- NAID
  10020529985
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Photochemical fishing approaches for identifying target proteins and elucidating the structure of a ligand-binding region using carbene-generating photoreactive probes2006
- Author(s)
  Y.Sadakane, Y.Hatanaka
- Journal Title
  
  Anal.Sci. 21
  
  Pages: 209-218
- NAID
  10017246234
- Data Source
  KAKENHI-PROJECT-16650077
[Journal Article] Analysis of Structural Alternations of L-Asp and L-Asn Residues in Peptides Related to Neuronal Disease.2006
- Author(s)
  Y.Sadakane, S.Kumamoto, K.Konoda, M.Kawahara, K.Nakagomi
- Journal Title
  
  Peptide Sciences 43
  
  Pages: 284-284
- NAID
  10020529985
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Photochemical fishing approaches for identifying target proteins and elucidating the structure of a ligand-binding region using carbene-gene rating photoreactive probes2006
- Author(s)
  Y.Sadakane, Y.Hatanaka
- Journal Title
  
  Anal.Sci. 22
  
  Pages: 209-218
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Photochemical fishing approaches for identifying target proteins and elucidating the structure of a ligand-binding region using carbene-generating photoreactive probes.2006
- Author(s)
  Y. Sadakane, Y. Hatanaka
- Journal Title
  
  Anal. Sci.(with peer review.) 22
  
  Pages: 109-218
- NAID
  10017246234
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Zinc neurotoxicity and its role in neurodegenerative diseases2006
- Author(s)
  Konoha K., Sadakane Y., Kawahara M
- Journal Title
  
  J.Health Sci., 52
  
  Pages: 1-8
- NAID
  110006163207
- Data Source
  KAKENHI-PROJECT-16650077
[Journal Article] Kinetic study of racemization of aspartyl residues in recombinant human α A-crystallin2006
- Author(s)
  T Nakamura, Y Sadakane, N.Fujii
- Journal Title
  
  BBA-Proteins and Proteomics 1764
  
  Pages: 800-806
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Simple and Versatile Method for Tagging Phenyldiazirine Photophores.2006
- Author(s)
  H. Nakashima, M. Hashimoto, Y. Sadakane, T. Tomohiro, Y. Hatanaka
- Journal Title
  
  J Am. Chem. Soc.(with peer review) 128
  
  Pages: 15092-15093
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Photoaffinity labeling of opioid-binding cell-adhesion molecule (OBCAM) by phenyldiazirine-integrated ligand2006
- Author(s)
  Y.sadakane, E.Kitamoto, T.Tomohiro, K.Konoha, M.Kawahara, Y.Hatanaka
- Journal Title
  
  J.KUHW 8
  
  Pages: 179-185
- NAID
  110006407510
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Pore formation and distuption of calciumhomeostasis by amyloidogenic peptidesincluding Alzheimer's beta-amyloid protein, prion protein fragment peptide, and aipha-synuclein fragment.2006
- Author(s)
  K. Konoha, Y. Sadakane, M. Kawahara
- Journal Title
  
  Alzheimer r Disease : New Advances(with peer review.)
  
  Pages: 323-327
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Kinetic study of racemization of aspartyl residues in recombinant human α A-crystallin.2006
- Author(s)
  T Nakamura, Y Sadakane, N. Fujii
- Journal Title
  
  BBA-Proteins and Proteomics 1764
  
  Pages: 800-806
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Carnosine protects GT 1-7 cell against zinc-induced neurotoxicity : a possible candidate for treatment for vascular type of dementia.2006
- Author(s)
  K. Konoha, Y. Sadakane, M. Kawahara
- Journal Title
  
  Trace Nutrients Research, (with peer review.) 23
  
  Pages: 1-8
- NAID
  40015330447
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Kinetic study of racemization of aspartyl residues in recombinant human αA-crystallin.2006
- Author(s)
  T Nakamura, Y Sadakane, N. Fujii
- Journal Title
  
  BBA - Proteins and Proteomics, (with peer review.) 1764
  
  Pages: 800-806
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Carnosine protects GT1-7 cell against zinc-induced neurotoxicity : a possible candidate for treatment for vascular type of dementia.2006
- Author(s)
  K.Konoha, Y.Sadakane, M.Kawahara
- Journal Title
  
  Trace Nutrients Research 23
  
  Pages: 1-8
- NAID
  40015330447
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Isolation of novel cathepsin B inhibitory peptides from enzymatic hydrolysates of human proteins.2006
- Author(s)
  H. Koyama ; M. Yasuda, K. Mawatari, K. Kaneko, Y. Sadakane, Y. Hatanaka, K. Nakagomi
- Journal Title
  
  Peptide Sciences.(with peer review.) 43
  
  Pages: 313-314
- NAID
  10020530123
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Pore formation and distuption of calciumhomeostasis by amyloidogenic peptides including Alzheimer's beta-amyloid protein,prion protein fragment peptide, and alpha-synuclein fragment2006
- Author(s)
  K.Konoha, Y.Sadakane, M.Kawahara
- Journal Title
  
  Alzheimer's Disease:New Advances
  
  Pages: 323-327
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Simple and Versatile Method for Tagging Phenyldiazirine Photophores2006
- Author(s)
  H.Nakashima, M.Hashimoto, Y.Sadakane, T.Tomohiro, Y.Hatanaka
- Journal Title
  
  J.Am.Chem.Soc. 128
  
  Pages: 15092-15093
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Zinc neurotoxicity and its role in neurodegenerative diseases2006
- Author(s)
  K.Konoha, Y.Sadakane, M.Kawahara
- Journal Title
  
  J.Health Sci. 52
  
  Pages: 1-8
- NAID
  110006163207
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Phenyldiazirine unit for converting peptides,proteins,DNAs,and sugars to photoaffinity ligands2006
- Author(s)
  Y.sadakane, M.Kaneda, H.Nakashima, T.Tomohiro, K.Konoha, M.Kawahara, Y.Hatanaka
- Journal Title
  
  Photomedicine and Photobiology 28
  
  Pages: 11-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Preparation of recombinant lysosomal cysteine proteases highly expressed in mouse placenta, cathepsin-P/J and -6.2005
- Author(s)
  Y.Sadakane, T.Ito, T.Tomohiro, K.Konoha, M.Kawahara, S.Imanishi, Y.Hatanaka, K.Nakagomi
- Journal Title
  
  J.Kyushu Univ.Health Welfare 6
  
  Pages: 287-298
- NAID
  110004633177
- Data Source
  KAKENHI-PROJECT-16650077
[Journal Article] Photoaffinity identification of DNA-binding proteins : Comparison of labeling efficiency between photoreactive DNAs bearing diazirine or benzophenone.2005
- Author(s)
  Y.Sadakane, T.Takagi, T.Tomohiro, K.Tsurusawa, K.Konoha, M.Kawahara, Y.Hatanaka
- Journal Title
  
  Photomedicine and Photobiology 26
  
  Pages: 35-40
- Data Source
  KAKENHI-PROJECT-16650077
[Journal Article] Synthesis of Diazirinyl Photoprobe Carrying a Novel Cleavable Biotin.2005
- Author(s)
  Park JJ., Sadakane Y., Masuda K., Tomohiro T., Nakano T., Hatanaka Y.
- Journal Title
  
  Chem Bio Chem 6
  
  Pages: 814-818
- Data Source
  KAKENHI-PROJECT-16650077
[Journal Article] Y. Hatanaka : Photoaffinity labeling of opioid-binding cell-adhesion molecule(OBCAM) by phenyldiazirine-integrated ligand.2005
- Author(s)
  Y. Sadakane, E. Kitamoto, T. Tomohiro, K. Konoha, M. Kawahara, Y. Hatanaka
- Journal Title
  
  J. KUHW(without peer review.) 8
  
  Pages: 179-185
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Journal Article] Protective activity of mango (Mangifera indica L.) fruit against a zinc-induced neuronal cell death is independent of its antioxidant activity2005
- Author(s)
  Sadakane Y., Konoha K., Kawahara M
- Journal Title
  
  Trace Nutrients Res 22
  
  Pages: 73-79
- NAID
  40015392247
- Data Source
  KAKENHI-PROJECT-16650077
[Journal Article] Effects of gadolinium and other metal on the neurotoxicity of immortalized hypothalamic neurons induced by zinc.2004
- Author(s)
  K.Konoha, Y.Sadakane, M.Kawahara
- Journal Title
  
  Biomed.Res.Trace Elements 15
  
  Pages: 275-277
- NAID
  10027573511
- Data Source
  KAKENHI-PROJECT-16650077
[Journal Article] A Cleavable Photophore for Identification of Peptides Forming the Ligand-Binding Region of Receptor Protein : Resistance of Streptavidin-Bound Peptide to Cleavage of Disulfide Linkage.2004
- Author(s)
  Y.Sadakane, Y.Hatanaka
- Journal Title
  
  Photomedicine and Photobiology 25
  
  Pages: 35-38
- Data Source
  KAKENHI-PROJECT-16650077
[Journal Article] Zinc homeostasis and neuronal death.2004
- Author(s)
  K.Konoha, Y.Sadakane, M.Kawahara
- Journal Title
  
  Trace Nutrients Research 21
  
  Pages: 77-83
- Data Source
  KAKENHI-PROJECT-16650077
[Journal Article] Identification of disulfide bonds and site-specific glycosylation in chicken alphal-acid glycoprotein by matrix-assisted laser desorption ionization time-of-flight mass spectrometry.2004
- Author(s)
  H.Matsunaga, Y.Sadakane, J.Haginaka
- Journal Title
  
  Anal.Biochem 331
  
  Pages: 358-363
- Data Source
  KAKENHI-PROJECT-16650077
[Journal Article] A Cleavable Photophore for Identification of Peptides Forming the Ligand-Binding Region of Receptor Protein : Resistance of Streptavidin-Bound Peptide to Cleavage of Disulfide Linkage2003
- Author(s)
  Sadakane Y., Hatanaka Y.
- Journal Title
  
  Photomedicine and Photobiology 25
  
  Pages: 35-38
- Data Source
  KAKENHI-PROJECT-14658185
[Journal Article] Analysis of structural alternations of L-Asp and L-Asn residures in peptides related to neuronal conformation disease.
- Author(s)
  Y. Sadakane, 他
- Journal Title
  
  KURRI report 2008 (in press)
- Data Source
  KAKENHI-PROJECT-20611021
[Journal Article] Synthesis of Diazirinyl Photoprobe Carrying a Novel Cleavable Biotin
- Author(s)
  JJ.Park, Y.Sadakane, K.Masuda, T.Tomohiro, T.Nakano, Y.Hatanaka
- Journal Title
  
  Chem Bio Chem (In press)
- Data Source
  KAKENHI-PROJECT-16650077
[Journal Article] Kinetic study of racemization of aspartyl residues in recombinant human αA-crystallin
- Author(s)
  T.Nakamura, Y.Sadakane, N.Fujii
- Journal Title
  
  BBA - Proteins and Proteomics In press
- Data Source
  KAKENHI-PROJECT-16650077
[Patent] 脳血管性認知症の治療剤および該治療剤を含有する飲食物、補助食品2009
- Inventor(s)
  川原正博、定金豊、木葉敬子
- Industrial Property Rights Holder
  九州保健福祉大学
- Patent Publication Number
  2009-249335
- Filing Date
  2009-10-29
- Data Source
  KAKENHI-PROJECT-21590145
[Patent] 脳血管性認知症の治療剤および該治療剤を含有する飲食物、補助食品2008
- Inventor(s)
  川原正博, 定金豊, 木葉敬子
- Industrial Property Rights Holder
  九州保健福祉大学
- Industrial Property Number
  2008-098675
- Filing Date
  2008-04-04
- Data Source
  KAKENHI-PROJECT-19590133
[Patent] 「脳血管性認知症の治療剤および該治療剤を含有する飲食物、補助食品」2008
- Inventor(s)
  川原正博、定金豊、木葉敬子
- Industrial Property Rights Holder
  九州保健福祉大学
- Industrial Property Number
  2008-098675
- Filing Date
  2008-04-04
- Data Source
  KAKENHI-PROJECT-19590133
[Patent] 光反応基を利用したパニング法およびそれに用いるキット(PANNING METHOD UTILIZING PHOTOREACTIVE GROUP AND KIT FOR THE METHOD)2007
- Inventor(s)
  畑中保丸, 定金豊
- Industrial Property Rights Holder
  国立大学法人富山大学
- Filing Date
  2007-01-22
- Description
  「研究成果報告書概要(和文)」より
- Overseas
- Data Source
  KAKENHI-PROJECT-18590114
[Patent] 「脳血管性認知症の予防または治療用飲食物、その包装または容器ならびに脳血管性認知症の予防または治療薬」2007
- Inventor(s)
  川原正博、定金豊、木葉敬子
- Industrial Property Rights Holder
  九州保健福祉大学
- Patent Publication Number
  2007-314467
- Acquisition Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19590133
[Patent] 光反応基を利用したパニング法およびそれに用いるキット2007
- Inventor(s)
  畑中保丸定金豊
- Industrial Property Rights Holder
  国立大学法人富山大学
- Filing Date
  2007-01-22
- Data Source
  KAKENHI-PROJECT-18590114
[Patent] NUCLEIC ACID DERIVATIVES HAVING PHENYLDIAZIR IDINE MOIETIES AND PROCESS FOR PRODUCTION THEREOF, NUCLEOTIDE DERIVATIVES HAVING PHENYLD IAZIRIDINE MOIETIES AND PROCESS FOR PRODUCTI ON THEREOF, METHOD FOR ANALYSIS OF PROTEIN, AND PROCESS FOR PREPAR ATION OF2006
- Inventor(s)
  Yasumaru HATANAKA, Yutaka SADAKANE, Masaki, KANEDA
- Industrial Property Rights Holder
  National University Corporation University of Toyama
- Filing Date
  2006-05-08
- Description
  「研究成果報告書概要(和文)」より
- Overseas
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] 光反応基を導入したDNAアプタマーの特性評価2024
- Author(s)
  定金　豊、坪倉朱里、笠井美月、伊藤優花、平井千尋、森本正大
- Organizer
  日本薬学会第144年会　（横浜）2024年3月29日
- Data Source
  KAKENHI-PROJECT-23K06088
[Presentation] シアリルルイスX糖鎖ミメティックペプチドの結合特異性プロファイルの作製2023
- Author(s)
  定金　豊、窪田安紘、大塚　功
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-19K07031
[Presentation] トロンビン結合性核酸アプタマーの光化学的結合性評価2023
- Author(s)
  定金　豊、笠井美月、伊藤優花、平井千尋、森本正大
- Organizer
  第45回日本光医学光生物学会　（島根）2023年６月23日
- Data Source
  KAKENHI-PROJECT-23K06088
[Presentation] 光反応基を導入したDNAアプタマーの分析面での評価2023
- Author(s)
  定金　豊、坪倉朱里、笠井美月、伊藤優花、平井千尋、森本正大
- Organizer
  バイオメディカル分析科学シンポジウム2023　（北海道）2023年7月28日
- Data Source
  KAKENHI-PROJECT-23K06088
[Presentation] 光反応基を導入したDNAアプタマーの分析面での評価2023
- Author(s)
  定金　豊、坪倉朱里、笠井美月、伊藤優花、平井千尋、森本正大
- Organizer
  バイオメディカル分析科学シンポジウム2023
- Data Source
  KAKENHI-PROJECT-19K07031
[Presentation] トロンビン結合性核酸アプタマーの光化学的手法を用いた結合特異性評価2023
- Author(s)
  笠井美月、伊藤優花、平井千尋、森本正大、定金　豊
- Organizer
  日本薬学会第143年会　（北海道）2023年3月27日
- Data Source
  KAKENHI-PROJECT-23K06088
[Presentation] トロンビン結合性核酸アプタマーの光化学的手法を用いた結合特異性評価2023
- Author(s)
  笠井美月、伊藤優花、平井千尋、森本正大、定金　豊
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-19K07031
[Presentation] トロンビン結合性核酸アプタマーの光化学的結合性評価2023
- Author(s)
  定金　豊、笠井美月、伊藤優花、平井千尋、森本正大
- Organizer
  第45回日本光医学光生物学会
- Data Source
  KAKENHI-PROJECT-19K07031
[Presentation] 光反応性核酸アプタマーの作製とその分析化学的応用2022
- Author(s)
  伊藤優花、平井千尋、森本正大、定金　豊
- Organizer
  第142年会　日本薬学会
- Data Source
  KAKENHI-PROJECT-19K07031
[Presentation] シアリルルイスX糖鎖ミメティックペプチドの結合特異性プロファイル2022
- Author(s)
  定金　豊、窪田安紘、大塚　功
- Organizer
  第12回新アミノ酸分析研究会
- Data Source
  KAKENHI-PROJECT-19K07031
[Presentation] 生体内異性化アミノ酸残基を同定する新規ラベル化法の開発2022
- Author(s)
  森本正大、杉野奈央、山口愛未、定金豊
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-19K07031
[Presentation] 光反応性核酸アプタマーの作製と結合特異性評価法の構築2022
- Author(s)
  定金　豊、伊藤優花、平井千尋、森本正大
- Organizer
  バイオメディカル分析科学シンポジウム2022
- Data Source
  KAKENHI-PROJECT-19K07031
[Presentation] ペプチド中のSer残基のラセミ化解析：分析法の確立とその配列特異性2022
- Author(s)
  小林瑞季、萩野　恵、森本正大、定金　豊
- Organizer
  第142年会　日本薬学会
- Data Source
  KAKENHI-PROJECT-19K07031
[Presentation] 光反応性核酸アプタマーによるアプタマー結合特異性の評価2022
- Author(s)
  定金　豊、伊藤優花、平井千尋、森本正大
- Organizer
  第44回日本光医学光生物学会
- Data Source
  KAKENHI-PROJECT-19K07031
[Presentation] 光反応性核酸アプタマーによるアプタマー結合特異性の評価2022
- Author(s)
  定金　豊、伊藤優花、平井千尋、森本正大
- Organizer
  第44回　光医学光生物学会
- Data Source
  KAKENHI-PROJECT-19K07031
[Presentation] 逆相HPLCによるペプチド中のSer残基の異性化解析2021
- Author(s)
  定金　豊、萩野　恵、森本正大
- Organizer
  日本薬学会　第141年会
- Data Source
  KAKENHI-PROJECT-19K07031
[Presentation] 新規ケミカルタグを用いた異性化アミノ酸部位同定手法の開発2021
- Author(s)
  森本正大, 鶴田大将, 山口愛未, 定金豊
- Organizer
  第16回　Dアミノ酸学会
- Data Source
  KAKENHI-PROJECT-19K07031
[Presentation] Ser残基の異性化解析のための逆相HPLC分離条件の検討2021
- Author(s)
  小林瑞希、森本正大、定金豊
- Organizer
  第11回　新アミノ酸分析研究会
- Data Source
  KAKENHI-PROJECT-19K07031
[Presentation] 新規ケミカルタグを用いたタンパク質内異性化Asp残基検出手法の開発2021
- Author(s)
  森本正大、山口愛未、鶴田大将、定金　豊
- Organizer
  日本薬学会　第141年会
- Data Source
  KAKENHI-PROJECT-19K07031
[Presentation] 1.変性条件下での結合解析を可能とする光反応性核酸アプタマーの作製法の開発2020
- Author(s)
  平井千尋、森本正大、定金豊
- Organizer
  日本薬学会第140年会（京都）
- Data Source
  KAKENHI-PROJECT-19K07031
[Presentation] 2.ケミカルプロテオミクス手法による生体内アミノ残基異性化部位検出法の開発2020
- Author(s)
  山口愛未、鶴田大将、森本正大、定金豊
- Organizer
  日本薬学会第140年会（京都）
- Data Source
  KAKENHI-PROJECT-19K07031
[Presentation] ペプチド中の Ser 残基の逆相 HPLC による異性化解析2020
- Author(s)
  定金　豊、萩野　恵、森本正大
- Organizer
  新アミノ酸分析研究会　第10回学術講演会
- Data Source
  KAKENHI-PROJECT-19K07031
[Presentation] タンパク質内のD－アミノ酸分析と神経変性疾患との関わり2019
- Author(s)
  定金　豊
- Organizer
  Dアミノ酸学会第4回ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-16K08207
[Presentation] 修復酵素PIMTを利用したタンパク質内のアミノ酸老化解析2019
- Author(s)
  森本正大、鶴田大将、田中温季、定金　豊
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K08207
[Presentation] タンパク質内でのアミノ酸残基の老化：高速キラル分析と生体機能への影響2019
- Author(s)
  定金　豊
- Organizer
  第79回分析化学討論会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07031
[Presentation] タンパク質内でのアミノ酸残基の老化：高速キラル分析と生体機能への影2019
- Author(s)
  定金　豊
- Organizer
  第79回分析化学討論会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08207
[Presentation] 4.スルホクリック指向型新規アミノ酸を用いた機能性ペプチドスクリーニングシステムの構築2019
- Author(s)
  森本正大、岡野壱郎、加藤三貴、定金豊
- Organizer
  新アミノ酸分析研究会第9回学術講演会
- Data Source
  KAKENHI-PROJECT-19K07031
[Presentation] 異性化修復酵素PIMTを利用したタンパク質内のアミノ酸構造変化の解析2018
- Author(s)
  森本正大、鶴田大将、田中温季、定金　豊
- Organizer
  新アミノ酸分析研究会第8回学術講演会
- Data Source
  KAKENHI-PROJECT-16K08207
[Presentation] 再現性の良いアミロイド線維形成条件の検討と阻害物質探索への応用2018
- Author(s)
  定金　豊、森下優花、森本正太
- Organizer
  第64回　日本薬学会東海支部学術大会
- Data Source
  KAKENHI-PROJECT-16K08207
[Presentation] 修復酵素 PIMT とヒドラジンを用いた化学修飾法による isoAsp 残基部位特定法の確立ための基礎的検討2018
- Author(s)
  鶴田大将，森本正大，定金豊
- Organizer
  第14回Dアミノ酸学会
- Data Source
  KAKENHI-PROJECT-16K08207
[Presentation] 糖鎖ミメティックペプチド結合特性の光アフィニティーラベリング分析2018
- Author(s)
  定金　豊，窪田安紘、藤原　将平，大塚　功
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K08207
[Presentation] スクシンイミド中間体の開環と閉環反応に及ぼすアミノ酸側鎖の影響2017
- Author(s)
  定金豊、千田紗弓、出口　拓
- Organizer
  第7回新アミノ酸研究会
- Data Source
  KAKENHI-PROJECT-16K08207
[Presentation] 光アフィニティーラベル法による糖鎖機能解明を志向した分子ツールの開発 -LeX 型糖鎖リガンドの合成2017
- Author(s)
  大塚功 , 定金豊 , 羽田紀康 , 渥美聡孝 , 垣内信子
- Organizer
  日本薬学会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16K08207
[Presentation] 光アフィニティーラベル法による糖鎖機能解明を志向した分子ツールの開発 sLeX 型糖鎖リガンドの合成2017
- Author(s)
  大塚功, 定金豊, 羽田紀康, 渥美聡孝, 垣内信子
- Organizer
  日本薬学会第137年会
- Data Source
  KAKENHI-PROJECT-16K08207
[Presentation] 光反応性糖鎖ミメティックペプチドを用いた結合解析法の開発2017
- Author(s)
  定金　豊，藤原　将平，大塚　功
- Organizer
  日本薬学会
- Place of Presentation
  仙台
- Year and Date
  2017-03-27
- Data Source
  KAKENHI-PROJECT-16K08207
[Presentation] 光反応性糖鎖ミメティックペプチドを用いた結合解析法の開発2017
- Author(s)
  定金　豊，藤原　将平，大塚　功
- Organizer
  日本薬学会第137年会
- Data Source
  KAKENHI-PROJECT-16K08207
[Presentation] 糖鎖ミメティックペプチド結合特異性の光化学的分析2017
- Author(s)
  定金　豊，窪田安紘、藤原　将平，大塚　功
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2017
- Data Source
  KAKENHI-PROJECT-16K08207
[Presentation] タンパク質中のアミノ酸残基の老化に伴う経時的構造変化を可視化する解析法の確立2016
- Author(s)
  定金豊、祖父江友宏、地主将典
- Organizer
  新アミノ酸研究会
- Place of Presentation
  東京
- Year and Date
  2016-11-04
- Data Source
  KAKENHI-PROJECT-16K08207
[Presentation] カルモジュリンのアミノ酸レベルの老化と構造解析法の確立2016
- Author(s)
  定金豊、祖父江友宏、地主将典
- Organizer
  Dアミノ酸学会
- Place of Presentation
  高知
- Year and Date
  2016-09-15
- Data Source
  KAKENHI-PROJECT-16K08207
[Presentation] 脳血管性認知症予防・治療薬としてのカルノシンの作用メカニズム解明2014
- Author(s)
  水野　大，高橋　千紘，金子　奈央，定金　豊，川原　正博
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23510286
[Presentation] 光反応性糖鎖ミメティックペプチドの合成とレクチン解析への応用2014
- Author(s)
  定金豊, 松下秀峰, 山路充宏, 大塚功
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23510286
[Presentation] プリオンタンパク質ペプチド断片のＮ末アミノ酸の構造変化と線維化速度への影響2013
- Author(s)
  宇佐美亜由子，山本理香子，定金　豊
- Organizer
  第59回日本薬学会東海支部大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23510286
[Presentation] プリオンタンパク質ペプチド断片のN末アミノ酸の構造変化と線維化速度への影響2013
- Author(s)
  宇佐美亜由子, 山本理香子, 定金豊
- Organizer
  第59回日本薬学会東海支部大会
- Place of Presentation
  名古屋
- Year and Date
  2013-07-06
- Data Source
  KAKENHI-PROJECT-23510286
[Presentation] プリオンタンパク質ペプチド断片のN末構造変化と線維化速度への影響2013
- Author(s)
  定金豊, 宇佐美亜由子, 山本理香子
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23510286
[Presentation] Molecular mechanism of zinc-induced neurodegeneration: involvement of calcium dyshomeostasis and carnosine2012
- Author(s)
  S. OHKAWARA, H. KOYAMA, Y. SADAKANE, M. KAWAHARA
- Organizer
  第22回金属の関与する生体関連反応シンポジウム
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23510286
[Presentation] PrP106-126の高次構造変化に重要な配列2012
- Author(s)
  小山裕也, 坂口哲陛, 定金豊, 川原正博
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23510286
[Presentation] 光反応性糖鎖リガンドを用いた結合解析法の効率化2012
- Author(s)
  定金豊, 山路充宏, 大塚功
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2012
- Place of Presentation
  岐阜
- Year and Date
  2012-11-18
- Data Source
  KAKENHI-PROJECT-23510286
[Presentation] Synthesis of new molecular tools for elucidation of carbohydrates roles by photoaffinity labeling: Carbohydrate - Carbohydrate-protein interactions are affected by different of glycosidic formations2012
- Author(s)
  I. Ohtsuka, Y. Sadakane, N. Hada, M. Higuchi, N. Kakiuchi
- Organizer
  International Carbohydrate Symposium
- Place of Presentation
  Spain
- Data Source
  KAKENHI-PROJECT-23510286
[Presentation] アルツハイマー β ペプチドの N 末側アミノ酸の構造的変化と線維化への影響2012
- Author(s)
  定金　豊，小山　裕也，川原　正博
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23510286
[Presentation] プリオンタンパク質断片ペプチド（106-126）のN末およびアスパラギン残基の構造変化によるアミロイド線維化速度への影響2012
- Author(s)
  定金　豊、宇佐美亜由子、山本理香子
- Organizer
  第８回Dアミノ酸研究会
- Place of Presentation
  滋賀
- Data Source
  KAKENHI-PROJECT-23510286
[Presentation] アルツハイマーβペプチドのN末側アミノ酸の構造的変化と線維化への影響2012
- Author(s)
  定金豊, 小山裕也, 川原正博
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23510286
[Presentation] 脳疾患に関連するペプチド中のアスパラギンおよびアスパラギン酸残基の構造変化と生理活性2012
- Author(s)
  定金豊, 小山裕也, 川原正博
- Organizer
  第57回日本薬学会東海支部大会
- Place of Presentation
  名古屋
- Year and Date
  2012-07-09
- Data Source
  KAKENHI-PROJECT-23510286
[Presentation] PrP106-126 の高次構造変化に重要な配列2012
- Author(s)
  小山　裕也，坂口哲陛，定金　豊，川原　正博
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23510286
[Presentation] アルツハイマーβペプチド断片のN末端の構造変化による線維化速度への影響2012
- Author(s)
  定金豊, 宇佐美亜由子, 山本理香子
- Organizer
  第58回日本薬学会東海支部大会
- Place of Presentation
  静岡
- Year and Date
  2012-07-07
- Data Source
  KAKENHI-PROJECT-23510286
[Presentation] プリオンタンパク質断片ペプチド(106-126)のN末およびアスパラギン残基の構造変化によるアミロイド線維化速度への影響2012
- Author(s)
  定金豊, 宇佐美亜由子, 山本理香子
- Organizer
  第8回Dアミノ酸研究会
- Place of Presentation
  滋賀
- Data Source
  KAKENHI-PROJECT-23510286
[Presentation] PrP106-126の高次構造変化に重要な配列2012
- Author(s)
  小山裕也,坂口哲陛,大河原晋,定金豊,川原正博
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21590145
[Presentation] 光アフィニティーラベル法による新規分子ツールの開発～糖鎖結合様式が認識に及ぼす影響を検証～2012
- Author(s)
  大塚功, 定金豊, 羽田紀康, 羽田純子, 新垣達司, 樋口真里, 垣内信子
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23510286
[Presentation] Synthesis of new molecular tools for elucidation of carbohydrates roles by photoaffinity labeling: Carbohydrate – Carbohydrate-protein interactions are affected by different of glycosidic formations.2012
- Author(s)
  I. Ohtsuka; Y. Sadakane; N. Hada, M. Higuchi; N. Kakiuchi
- Organizer
  International Carbohydrate Symposium
- Place of Presentation
  Spain
- Data Source
  KAKENHI-PROJECT-23510286
[Presentation] 還元末端が閉環した構造をもつ光反応性糖鎖リガンドの合成と結合解析法の確立2012
- Author(s)
  定金豊, 大塚功, 山路充宏, 畑中保丸
- Organizer
  第34回日本光医学・光生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23510286
[Presentation] アルツハイマーβペプチドのN末側アミノ酸の構造的変化と線維化への影響2012
- Author(s)
  定金豊,小山裕也,川原正博
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21590145
[Presentation] (カンファレンス講演)光を利用して化学と生物とをつなぐ新技術を開発する2011
- Author(s)
  定金豊
- Organizer
  順正学園学術カンファレンス
- Place of Presentation
  延岡
- Year and Date
  2011-03-06
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] 部位特異的カルベン発生型DNA, ペプチド, タンパク質の作製ツールの開発2011
- Author(s)
  定金豊, 畑中保丸
- Organizer
  第33回日本光医学・光生物学会
- Place of Presentation
  大阪
- Year and Date
  2011-07-23
- Data Source
  KAKENHI-PROJECT-23510286
[Presentation] 部位特異的カルベン発生型DNA，ペプチド，タンパク質の作製ツールの開発2011
- Author(s)
  定金　豊，畑中保丸
- Organizer
  第33回　日本光医学・光生物学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23510286
[Presentation] Zinc, copper, and carnosine attenuate neurotoxicity of prion fragment PrP106-1262011
- Author(s)
  Koyama H, Okahara M, Sakaguchi T, Sadakane Y and Kawahara M
- Organizer
  5th International Conference on Metals and Genetics
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-21590145
[Presentation] 光を利用して化学と生物とをつなぐ新技術を開発する2011
- Author(s)
  定金豊
- Organizer
  順正学園学術カンファレンス
- Place of Presentation
  延岡
- Year and Date
  2011-03-06
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] 神経疾患に関わるペプチド断片の機能とアミノ酸レベルの構造変化：アミロイド線維化と細胞毒性への影響2011
- Author(s)
  定金　豊
- Organizer
  京都大学原子炉実験所・専門研究会　「第4回　タンパク質の異常凝集とその防御・修復機構に関する研究会」(招待講演)
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23510286
[Presentation] PrP断片ペプチドに対する亜鉛および銅の影響2011
- Author(s)
  小山裕也,永田哲也,定金豊,川原正博
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21590145
[Presentation] 神経疾患に関わるペプチド断片の機能とアミノ酸レベルの構造変化:アミロイド線維化と細胞毒性への影響2011
- Author(s)
  定金豊
- Organizer
  京都大学原子炉実験所・専門研究会「第4回タンパク質の異常凝集とその防御・修復機構に関する研究会」
- Place of Presentation
  大阪
- Year and Date
  2011-11-11
- Invited
- Data Source
  KAKENHI-PROJECT-23510286
[Presentation] コンフォメーション病に関与するペプチド中のアスanti-stressanti-oxidantanti-glycationanti-painanti-crosslink(Alzheimer, prion) pHbalanceCarnosineCH2CH2CNHOCHCCH2OHONNHH2Nパラギンおよびアスパラギン酸残基の構造変化と生理活性2011
- Author(s)
  定金豊,小山裕也,川原正博
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21590145
[Presentation] プリオンペプチド断片(106-126)中のアスパラギン残基の自発的構造変化と生理機能2010
- Author(s)
  定金豊,小山裕也、大塚功、川原正博
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21590145
[Presentation] Alterations of gene expressions during neuronal death after zinc exposure : implications of calcium dyshomeostasis2010
- Author(s)
  Kawahara M., Koyama H., Sadakane Y.
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-21590145
[Presentation] Effects of zinc and copper on conformational changes and neurotoxicity of prion fragment peptide (PrP106-126)2010
- Author(s)
  小山裕也、定金豊、大塚功、川原正博
- Organizer
  第20回金属の関与する生体関連反応シンポジウム(SRM2010)
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] Effects of zinc and copper on conformational changes and neurotoxicity of prion fragment peptide (PrP106-126)2010
- Author(s)
  小山裕也、定金豊、大塚功、川原正博
- Organizer
  第20回金属の関与する生体関連反応シンポジウム(SRM2010)
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21590145
[Presentation] Effects of zinc and copper on conformational changes and neurotoxicity of prion fragment peptide(PrP106-126)2010
- Author(s)
  小山裕也、定金豊、大塚功、川原正博
- Organizer
  第20回金属の関与する生体関連反応シンポジウム
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21590145
[Presentation] アスパラギンおよびアスパラギン酸残基の構造的変化解析:神経疾患機構との繋がりを求めて2010
- Author(s)
  定金豊
- Organizer
  第3回タンパク質の異常凝集とその防御・修復機構に関する研究会
- Place of Presentation
  大阪
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] プリオンペプチド断片(106-126)中のアスパラギン残基の自発的構造変化と生理機能2010
- Author(s)
  定金豊
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Year and Date
  2010-12-11
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] プリオンペプチド断片中のアスパラギン残基の構造的変化と生理活性2010
- Author(s)
  定金豊
- Organizer
  第130年会日本薬学会
- Place of Presentation
  岡山
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] プリオン蛋白断片ペプチドのコンフォメーション変化と神経毒性に及ぼす微量金属の影響2010
- Author(s)
  川原正博、小山裕也、定金豊
- Organizer
  第2回メタロミクス研究フォーラム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] プリオンペプチド断片中のアスパラギン残基の構造的変化と生理活性2010
- Author(s)
  定金豊
- Organizer
  第130年会日本薬学会
- Place of Presentation
  岡山
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21590145
[Presentation] プリオンペプチド断片(106-126)中のAsn残基の構造的変化と生理活性について2010
- Author(s)
  定金豊
- Organizer
  第6回-アミノ酸研究会学術講演会
- Place of Presentation
  富山
- Year and Date
  2010-09-17
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] PrP断片ペプチドの神経毒性に対する亜鉛および銅の影響2010
- Author(s)
  小山裕也、永田哲也、定金豊、川原正博
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21590145
[Presentation] Synthesis of new molecular tools for elucidation of carbohydrates roles by photoaffinity labeling : Carbohydrate-protein interactions are affected by different of glycosidic formations.2010
- Author(s)
  I.Ohtsuka ; Y.Sadakane ; M.Higuchi ; N.Kakiuchi ; A.Sakushima
- Organizer
  PACIFICHEM 2010
- Place of Presentation
  Hawaii
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] carnosine誘導体合成とGT1-7系における神経細胞保護効果2010
- Author(s)
  鳥や尾篤、宮越辰則、反田和宏,渡邉暁子、坂本正徳、木葉敬子、定金豊、川原正博、山崎哲郎
- Organizer
  日本薬学会第130回年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-21590145
[Presentation] 光アフィニティーラベル法による糖鎖機能解明を目指した新規分子ツールの創製2010
- Author(s)
  大塚功,定金豊,樋口真理,佐久島明世
- Organizer
  日本薬学会第130回年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] 光アフィニティーラベル法による糖鎖機能解明を目指した新規分子ツールの開発2010
- Author(s)
  大塚功,定金豊,樋口真里,垣内信子
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Year and Date
  2010-12-11
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] アスパラギンおよびアスパラギン酸残基の構造的変化解析:神経疾患機構との繋がりを求めて京都大学原子炉実験所・専門研究会2010
- Author(s)
  定金豊
- Organizer
  第3回タンパク質の異常凝集とその防御・修復機構に関する研究会
- Place of Presentation
  大阪(招待講演)
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] 糖鎖機能の効率的化未明を目指した光反応性糖鎖リガンドの製作2010
- Author(s)
  定金豊,大塚功,川原正博,畑中保丸
- Organizer
  第32回日本光医学・光生物学会
- Place of Presentation
  東京
- Year and Date
  2010-07-30
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] 糖鎖機能の効率的化未明を目指した光反応性糖鎖リガンドの製作2010
- Author(s)
  定金豊,大塚功,川原正博,畑中保丸
- Organizer
  第32回日本光医学・光生物学会
- Place of Presentation
  東京
- Year and Date
  2010-07-30
- Data Source
  KAKENHI-PROJECT-21590145
[Presentation] プリオンペプチド断片(106-126)中のAsn残基の構造的変化と生理活性について2010
- Author(s)
  定金豊,小山裕也,大塚功,木葉敬子,川原正博
- Organizer
  第6回D-アミノ酸研究会学術講演会
- Place of Presentation
  富山
- Year and Date
  2010-09-17
- Data Source
  KAKENHI-PROJECT-21590145
[Presentation] プリオン蛋白断片ペプチドのコンフォメーション変化と神経毒性に及ぼす微量金属の影響2010
- Author(s)
  川原正博、小山裕也、定金豊
- Organizer
  第2回メタロミクス研究フォーラム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21590145
[Presentation] Alterations of gene expressions during neuronal death after zinc exposure : implications of calcium dyshomeostasis2010
- Author(s)
  Kawahara M., Koyama H., Sadakane Y.
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] 微量金属の神経毒性と神経変性疾患2010
- Author(s)
  川原正博,定金豊,小山裕也
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] プリオン蛋白による培養細胞に対する亜鉛および銅の影響2010
- Author(s)
  小山裕也,永田哲也,定金豊,大塚功,戸泉文江,横山祥子,川原正博
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-21590145
[Presentation] Analysis of Alternation of A-Asp and L-Asn residures in peptides related to conformational disease2009
- Author(s)
  Sadakane Y, Konoha K, Kawahara M, Nakagomi K
- Organizer
  International D-amino acid Research (IDAR2009)
- Place of Presentation
  Awaji Irland, Japan
- Year and Date
  2009-07-01
- Data Source
  KAKENHI-PROJECT-21590145
[Presentation] プリオン蛋白断片ペプチドPrP106-126 のコンフォーメーションの違いによる細胞膜中における糖脂質認識能について-原子間力顕微法による直接観察2009
- Author(s)
  大塚功,永田哲也,木葉敬子,定金豊,川原正博,横山祥子
- Organizer
  日本薬学会第129 回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] 糖鎖結合タンパク質に適した光化学的スクリーニング法の開発2009
- Author(s)
  定金豊,木葉敬子,川原正博,畑中保丸
- Organizer
  第26回日本薬学会九州支部大会
- Place of Presentation
  福岡
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] 微量元素の神経毒性と老年性認知症の発症メカニズム2009
- Author(s)
  川原正博, 永田哲也, 大塚功, 木葉敬子, 定金豊, 横山祥子
- Organizer
  日本薬学会シンポジウム「金属の関与する生命科学(II) トキシコメタロミクス研究の新展開~最新分析法開発から創薬、診断、治療へのアプローチ」
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] Analysis of Alternation of A-Asp and L-Asn residures in peptides related to conformational disease2009
- Author(s)
  Sadakane Y, Konoha K, Kawahara M, Nakagomi K
- Organizer
  International D-amino acid Research
- Place of Presentation
  Awazi Inland, Japan
- Year and Date
  2009-07-05
- Data Source
  KAKENHI-PROJECT-21590145
[Presentation] HPLC によるラット脳内カルノシンの定量2009
- Author(s)
  木葉敬子,定金豊,永田哲也,川原正博
- Organizer
  日本薬学会第129 回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] 微量元素の神経毒性と老年性認知症の発症メカニズム2009
- Author(s)
  川原正博, 永田哲也, 大塚功, 木葉敬子, 定金豊, 横山祥
- Organizer
  日本薬学会第129回年会シンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] 糖鎖結合タンパク質に適した光化学的スクリーニング法の開発2009
- Author(s)
  定金豊
- Organizer
  第26回日本薬学会九州支部大会
- Place of Presentation
  福岡
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] Analysis of Alternation of A-Asp and L-Asn residures in peptides related to conformational disease.2009
- Author(s)
  Y.Sadakane, K.Konoha, M.Kawahara, K.Nakagomi
- Organizer
  International D-amino acid Research (IDAR2009)
- Place of Presentation
  Awazi Inland, Japan
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] Carnosine inhibits s-sheet formation of PrP106-126 and protects against its neurotoxicity2009
- Author(s)
  Kawahara M, T. Nagata, K. Konoha, Y. Sadakane
- Organizer
  International Conference on Alzheimer's disease and related disorders
- Place of Presentation
  Wien
- Data Source
  KAKENHI-PROJECT-21590145
[Presentation] HPLCによるラット脳内カルノシンの定量2009
- Author(s)
  木葉敬子, 定金豊, 永田哲也, 川原正博
- Organizer
  日本薬学会第129回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] 中枢神経保護作用を目的としたL-carnosine 誘導体の合成2009
- Author(s)
  宮越辰則,鳥ヤ尾篤,渡邉暁子,坂本正徳,木葉敬子,定金豊,川原正博,山崎哲郎
- Organizer
  日本薬学会第129 回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] 環状L-carnosine誘導体の合成とその生物学的評価2009
- Author(s)
  鳥や尾篤, 宮越辰則, 渡邉暁子, 坂本正徳, 木葉敬子, 定金豊, 川原正博, 山崎哲郎
- Organizer
  日本薬学会第129回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] アルツハイマーβアミロイドペプチドの自己構造変化を認識する抗体作製と応用2009
- Author(s)
  定金豊, 他
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] 光反応性生体高分子リガンドの開発と光化学的スクリーニング法への応用2009
- Author(s)
  定金豊,大塚功,木葉敬子,畑中保丸
- Organizer
  第31回日本光医学・光生物学会
- Place of Presentation
  大阪
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] 糖鎖機能の効率的化未明を目指した光反応性糖鎖リガンドの製作2009
- Author(s)
  定金豊
- Organizer
  第32回日本光医学・光生物学会
- Place of Presentation
  東京
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] 糖鎖結合タンパク質に適した光化学的スクリーニング法の開発2009
- Author(s)
  定金豊
- Organizer
  第26回日本薬学会九州支部大会
- Place of Presentation
  福岡
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-21590145
[Presentation] プリオン蛋白断片ペプチドPrP106-126のコンフォーメーションの違いによる細胞膜中における糖脂質認識能について-原子間力顕微法による直接観察2009
- Author(s)
  大塚功, 永田哲也, 木葉敬子, 定金豊, 川原正博, 横山祥子
- Organizer
  日本薬学会第129回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] 微量元素の神経毒性と老年性認知症の発症メカニズム2009
- Author(s)
  川原正博,永田哲也,大塚功,木葉敬子,定金豊,横山祥子
- Organizer
  日本薬学会シンポジウム「金属の関与する生命科学(II)トキシコメタロミクス研究の新展開～最新分析法開発から創薬、診断、治療へのアプローチ」
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] アルツハイマーβアミロイドペプチドの自己構造変化を認識する抗体作製と応用2009
- Author(s)
  定金豊,木葉敬子
- Organizer
  日本薬学会第129回年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] 糖鎖結合タンパク質に適した光化学的スクリーニング法の開発2009
- Author(s)
  定金豊,木葉敬子,川原正博,畑中保丸
- Organizer
  第26回日本薬学会九州支部大会
- Place of Presentation
  福岡
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-21590145
[Presentation] Analysis of Alternation of A-Asp and L-Asn residures in peptides related to conformational disease2009
- Author(s)
  Sadakane Y
- Organizer
  International D-amino acid Research (IDAR2009)
- Place of Presentation
  日本淡路島
- Year and Date
  2009-07-01
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] 神経疾患に関わるペプチド中のアスパラギンおよびアスパラギン酸残基の構造的変化と生理活性2009
- Author(s)
  定金豊
- Organizer
  京都大学原子炉実験所・専門研究会「第2回タンパク質の異常凝集とその防御・修復機構に関する研究会」
- Place of Presentation
  大阪
- Year and Date
  2009-11-12
- Data Source
  KAKENHI-PROJECT-21590145
[Presentation] Carnosine inhibits β-sheet formation of PrP106-126 and protects against its neurotoxicity.2009
- Author(s)
  Kawahara M, Nagata T, Konoha K, Sadakane Y
- Organizer
  Alzheimer's Association International Conference on Alzheimer's Disease 2009
- Place of Presentation
  Wien, Austria
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] 神経疾患に関わるペプチド中のアスパラギンおよびアスパラギン酸残基の構造的変化と生理活性2009
- Author(s)
  定金豊
- Organizer
  京都大学原子炉実験所・専門研究会
- Place of Presentation
  大阪
- Year and Date
  2009-11-12
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] プリオン蛋白断片ペプチドPrP106-126のコンフォーメーションの違いによる細胞膜中における糖脂質認識能について-原子間力顕微法による直接観察2009
- Author(s)
  大塚功,永田哲也,木葉敬子,定金豊,川原正博,横山祥子
- Organizer
  日本薬学会第129回年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] 光反応性生体高分子リガンドの開発と光化学的スクリーニング法への応用2009
- Author(s)
  定金豊
- Organizer
  第31回日本光医学・光生物学会
- Place of Presentation
  大阪
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] 中枢神経保護作用を目的としたL-carnosine誘導体の合成2009
- Author(s)
  宮越辰則, 鳥ヤ尾篤, 渡邉暁子, 坂本正徳, 木葉敬子, 定金豊, 川原正博, 山崎哲郎
- Organizer
  日本薬学会第129回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] 環状 L-carnosine 誘導体の合成とその生物学的評価2009
- Author(s)
  鳥や尾篤,宮越辰則,渡邉暁子,坂本正徳,木葉敬子,定金豊,川原正博,山崎哲郎
- Organizer
  日本薬学会第129 回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] Carnosine inhibits β-sheet formation of PrP106-126 and protects against its neurot oxicitv2009
- Author(s)
  Kawahara M, Nagata T, Konoha K, Sadakane Y
- Organizer
  International Conference of Alzheimer's Disease (ICAD2009)
- Place of Presentation
  Wien, Austria
- Data Source
  KAKENHI-PROJECT-21590145
[Presentation] Inhibitory mechanism of metal ionsonzinc-induced neurotoxicity of culturedneuronal cells.2008
- Author(s)
  K. Konoha, Y. Sadakane, T. Nagata, M. Kawahara
- Organizer
  128th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2008-03-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] プリオン断片蛋白PrP106-126のコンフォーメーシヨンの違いによるGM1への認識能の変化-原子間力顕微法による直接観察2008
- Author(s)
  大塚功, 永田哲也, 木葉敬子, 定金豊, 川原正博, 横山祥子
- Organizer
  第25回日本薬学会九州支部大会
- Place of Presentation
  宮崎(延岡)
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] アルツハイマーβアミロイドペプチドの自己構造変化の検出法について2008
- Author(s)
  定金豊, 他
- Organizer
  第4回D-アミノ酸研究会学術講演会
- Place of Presentation
  名古屋
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] プリオン蛋白による培養神経細胞に対する毒性メカニズムの検討2008
- Author(s)
  永田哲也、木葉敬子、定金豊、川原正博
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] 亜鉛による培養神経細胞死に対する金属イオンの阻害メカニズムの検討2008
- Author(s)
  木葉敬子,永田哲也、定金豊,川原正博
- Organizer
  日本薬学会第128 年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] GT1-7マウス神経株化細胞を用いた亜鉛による神経細胞死メカニズムの解明2008
- Author(s)
  定金豊, 他
- Organizer
  第18回金属の関与する生体関連反応シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2008-06-05
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] Zinc-induced neuronal cell death : inhibitory activity of citric acid and its Zinc-inducedmechanism.2008
- Author(s)
  Y. Sadakane, K. Konoha, T. Nagata, M.Kawahara
- Organizer
  128th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2008-03-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] プリオン蛋白による培養神経細胞に対する毒性メカニズムの検討2008
- Author(s)
  永田哲也, 定金豊, 木葉敬子, 川原正博
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] ジアジリンを利用した光化学的スクリーニング法の開発2008
- Author(s)
  定金豊、木葉敬子、畑中保丸
- Organizer
  第21回バイオメディカル分析科学シンポジウム
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] 魚介類水抽出液からの脳血管認知症予防物質の単離と同定2008
- Author(s)
  定金豊、木葉敬子、永田哲也、川原正博
- Organizer
  日本微量栄養素学会第25 回学術集会
- Place of Presentation
  京都
- Year and Date
  2008-05-30
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] L-Carnosine誘導体の合成と生理作用について2008
- Author(s)
  宮越辰則、鳥や尾篤、渡邉暁子、坂本正徳、木葉敬子、定金豊、川原正博、山崎哲郎
- Organizer
  第25 回日本薬学会九州支部大会
- Place of Presentation
  延岡
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] 亜鉛による神経細胞死を抑制する成分:魚介類バイオマスからの単離と同定2008
- Author(s)
  木葉敬子、定金豊、永田哲也、川原正博
- Organizer
  第21 回バイオメディカル分析科学シンポジウム
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] 亜鉛による神経細胞死:クエン酸の抑制活性とそのメカニズムについて2008
- Author(s)
  定金豊, 木葉敬子, 永田哲也, 川原正博
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] 亜鉛による培養神経細胞死に対する金属イオンの阻害メカニズムの検討2008
- Author(s)
  木葉敬子, 永田哲也, 定金豊, 川原正博
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] マウス神経株化細胞を用いた亜鉛による神経細胞死メカニズムの解明2008
- Author(s)
  定金豊、木葉敬子、永田哲也、川原正博
- Organizer
  第18 回金属の関与する生体関連反応シンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] L-Carnosine誘導体の合成と生理作用について2008
- Author(s)
  宮越辰則, 鳥や尾篤, 渡邉暁子, 坂本正徳, 木葉敬子, 定金豊, 川原正博, 山崎哲郎
- Organizer
  第25回日本薬学会九州支部大会
- Place of Presentation
  宮崎(延岡)
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] YOKOYAMA Effects of trace elements on prion-induced neurotoxicity of primary cultured hippocampal neurons2008
- Author(s)
  M.KAWAHARA, T.NAGATA1, OHTSUKA, K.KONOHA, Y.SADAKANE, S
- Organizer
  Neuroscience 2008
- Place of Presentation
  Washington D.C., U.S.A.
- Year and Date
  2008-11-19
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] 亜鉛による神経細胞死を抑制する成分 : 魚介類バイオマスからの単離と同定2008
- Author(s)
  木葉敬子, 定金豊, 永田哲也, 川原正博
- Organizer
  第21回バイオメディカル分析科学シンポジウム
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] GTl-7マウス神経株化細胞を用いた亜鉛による神経細胞死メカニズムの解明2008
- Author(s)
  定金豊, 木葉敬子, 永田哲也, 川原正博
- Organizer
  第18回金属の関与する生体関連反応シンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] プリオン蛋白による培養神経細胞に対する亜鉛および銅の影響2008
- Author(s)
  永田哲也, 木葉敬子, 定金豊, 川原正博
- Organizer
  第19回日本微量元素学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] Effects of trace elements on prion-induced neurotoxicity of primary cultured hippocampal neurons2008
- Author(s)
  M. KAWAHARA, T. NAGATAl, OHTSUKA, K. KONOHA, Y. SADAKANE, S. YOKOYAMA
- Organizer
  Neuroscience 2008
- Place of Presentation
  Washington D. C., U. S. A
- Year and Date
  2008-11-19
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] プリオン蛋白による培養神経細胞に対する毒性メカニズムの検討2008
- Author(s)
  永田哲也、定金豊,木葉敬子、川原正博
- Organizer
  日本薬学会第128 年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] Endeavors to make the photophore, diazirine easy to use : Anapplication to biochemical methodology.2008
- Author(s)
  Y. Sadakane, Y. Hatanaka
- Organizer
  128th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2008-03-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] 光化学的スクリーニング法の開発2008
- Author(s)
  定金豊、木葉敬子、畑中保丸
- Organizer
  第30回日本光医学・光生物学会
- Place of Presentation
  島根
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] プリオン断片蛋白PrP106-126のコンフォーメーションの違いによるGM1への認識能の変化-原子間力顕微法による直接観察2008
- Author(s)
  大塚功、永田哲也、木葉敬子、定金豊、川原正博、横山祥子
- Organizer
  第25回日本薬学会九州支部大会
- Place of Presentation
  (延岡)
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] プリオン断片蛋白PrP106-126 のコンフォーメーションの違いによるGM1 への認識能の変化-原子間力顕微法による直接観察2008
- Author(s)
  大塚功、永田哲也、木葉敬子、定金豊、川原正博、横山祥子
- Organizer
  第25 回日本薬学会九州支部大会
- Place of Presentation
  延岡
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] Molecular mechanism of neurotoxicity induced by prion protein peptide.2008
- Author(s)
  T. Nagata, Y.Sadakane, K. Konoha, M.Kawahara
- Organizer
  128th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2008-03-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] 亜鉛による培養神経細胞死に対する金属イオンの阻害メカニズムの検討2008
- Author(s)
  木葉敬子、定金豊、永田哲也、川原正博
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] 魚介類水抽出液からの脳血管認知症予防物質の単離と同定2008
- Author(s)
  定金豊, 木葉敬子, 永田哲也, 川原正博
- Organizer
  日本微量栄養素学会第25回学術集会
- Place of Presentation
  京都
- Year and Date
  2008-05-30
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] Asp残基の構造変化分析法の開発とコンフォメーション病への応用2008
- Author(s)
  定金豊, 他
- Organizer
  京都大学原子炉実験所・専門研究会「タンパク質の異常凝集とその防御・
- Place of Presentation
  大阪
- Year and Date
  2008-10-02
- Data Source
  KAKENHI-PROJECT-20611021
[Presentation] 亜鉛による神経細胞死:クエン酸の抑制活性とそのメカニズムについて2008
- Author(s)
  定金豊,木葉敬子,永田哲也、川原正博
- Organizer
  日本薬学会第128 年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] プリオン蛋白による培養神経細胞に対する亜鉛および銅の影響2008
- Author(s)
  永田哲也、木葉敬子、定金豊、川原正博
- Organizer
  第19 回日本微量元素学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] 光反応基ジアジリンを利用した生化学的手法の開拓2008
- Author(s)
  定金豊、畑中保丸
- Organizer
  日本薬学会128年会シンポジウム(招待講演)
- Place of Presentation
  横浜・パシフィコ横浜
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] 光反応基ジアジリンを利用した生化学的手法の開拓2008
- Author(s)
  定金豊, 畑中保丸
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Effects of trace elements on prion-induced neurotoxicity of primary cultured hippocampal neurons2008
- Author(s)
  M. KAWAHARA, T. NAGATA, OHTSUKA, K. KONOHA, Y. SADAKANE, S. YOKOYAMA
- Organizer
  Neuroscience 2008
- Place of Presentation
  Washington D.C., U.S.A.
- Year and Date
  2008-11-19
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] L-β-アスパラギン酸含有ペプチドの逆相HPLC定量法によるアスパラギン酸残基の異性化速度の解析:タンパク質の高次構造との関係2007
- Author(s)
  定金豊, 木葉敬子, 永田哲也, 川原正博, 中込和哉, 藤井紀子
- Organizer
  第3回D-アミノ酸研究会
- Place of Presentation
  徳島
- Year and Date
  2007-09-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] レトロインバルソ型カテプシンB阻害ペプチドの合成2007
- Author(s)
  小山裕也, 若宮哲郎, 安田誠, 馬渡健一, 金子希代子, 中込和哉, 箕浦憲彦, 定金豊, 畑中保丸
- Organizer
  日本薬学会第127年会
- Place of Presentation
  富山
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] クエン酸による神経細胞死抑制活性とその作用機構の解明2007
- Author(s)
  定金豊,木葉敬子,永田哲也、川原正博
- Organizer
  第24 回日本薬学会九州支部大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] Kinetic analysis of rate constants of racemization at Asp36 and Asp62 residues in human alpha B-crystallin mutants, and their structure-function relationship.2007
- Author(s)
  T. Nakamura, M. Sakai, Y. Sadakane, T. Haga, Y. Goto, T. Kinouchi, T. Sato, N. Fujii
- Organizer
  3rd D-amino acid research meeting
- Place of Presentation
  Tokushima, Japan
- Year and Date
  2007-09-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Mechanism for zinc-induced neuronal cell death.2007
- Author(s)
  K. Konoha, T. Nagata, Y. Sadakane, M. Kawahara
- Organizer
  17th Symposium on Role of Metals in Biological Reactions, Biology and Medicine
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2007-06-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] クエン酸による神経細胞死抑制活性とその作用機構の解明2007
- Author(s)
  定金豊, 木葉敬子, 永田哲也, 川原正博
- Organizer
  第24回日本薬学会九州支部大会
- Place of Presentation
  福岡
- Year and Date
  2007-12-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] 亜鉛による培養神経細胞死メカニズムの検討2007
- Author(s)
  木葉敬子, 永田哲也, 定金豊, 川原正博
- Organizer
  第17回金属の関与する生体関連反応シンポジウム
- Place of Presentation
  京都
- Year and Date
  2007-06-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] 亜鉛による培養神経細胞死メカニズムの検討2007
- Author(s)
  木葉敬子、定金豊、永田哲也、川原正博
- Organizer
  第17回金属の関与する生体関連反応シンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] カルノシンによる神経細胞死抑制活性とその作用機構の解明2007
- Author(s)
  定金豊, 木葉敬子, 川原正博
- Organizer
  日本薬学会第127年会
- Place of Presentation
  富山
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Zinc-induced apoptosis of GT1-7 cells are protected by mango(Mangifera indica L.)fruit:a candidate for treatment of neurodegeneration after ischemia2007
- Author(s)
  M.Kawahara, K.Konoha, T.Nagata, Y.Sadakane
- Organizer
  Neuroscience 2007
- Place of Presentation
  San Diego,USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] マンゴー(Mangifera indica L.)果実抽出液の神経細胞死抑制活性成分の同定2007
- Author(s)
  木葉敬子, 定金豊, 川原正博
- Organizer
  日本薬学会第127年会
- Place of Presentation
  富山
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Synthesis of Cathepsinn B inhibitory retro-inverso peptidyl analogues.2007
- Author(s)
  Y. Koyama, T. Wakamiya, M. Yasuda, K. Mawatari, K. Kaneko, K. Kazuya, N. Minoura, Y. Sadakane, Y. Hatanaka
- Organizer
  127th Annual Meeting of the Pharmaceutical Society of apan
- Place of Presentation
  Toyama, Japan
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Characterization of inhibitory compounds in Mangifera indica L.fruit extract, which suppress the zinc-induced neurotoxicity of immortalized hypothalamic neurons.2007
- Author(s)
  K. Konoha, Y. Sadakane, M. Kawahara
- Organizer
  127th Annual Meeting of the Pharmaceutical Society of apan
- Place of Presentation
  Toyama, Japan
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] アルミニウムのラット大脳皮質培養神経細胞に対する毒性の化学形態による比較2007
- Author(s)
  木葉敬子、定金豊、永田哲也、川原正博
- Organizer
  第18回日本微量元素学会
- Place of Presentation
  福井
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] Zinc-induced apoptosis of GT1-7 cells are protected by mango(Mangifera indica L.)fruit: a candidate for treatment of neurodegeneration after ischemia2007
- Author(s)
  M. Kawahara, K. Konoha, T. Nagata, Y. Sadakane
- Organizer
  Neuroscience 2007(Society for Neuroscience)
- Place of Presentation
  San Diego(U.S.A.)
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] 農産物・魚介類中における脳血管性認知症予防物質の探索と単離,構造解析2007
- Author(s)
  川原正博, 木葉敬子, 永田哲也, 定金豊
- Organizer
  第24回微量栄養素研究会シンポジウム
- Place of Presentation
  京都
- Year and Date
  2007-06-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Zinc-induced apoptosis of GT1-7 cells are protected by mango (Mangifera indica L.) fruit: a candidate for treatment of neurodegeneration after ischemia2007
- Author(s)
  M. Kawahara, K. Konoha, T. Nagata, Y. Sadakane
- Organizer
  Neuroscience 2007 (Society for Neuroscience)
- Place of Presentation
  San Diego (U.S.A.)
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] Photoaffinity-Based Binding Analysis of CDDP-Damaged DNA-Protein Complex.2007
- Author(s)
  T. Tomohiro, S. Ishihara, H. Jinguji, Y. Sadakane, Y. Hatanaka
- Organizer
  127th Annual Meeting of the Pharmaceutical Society of apan
- Place of Presentation
  Toyama, Japan
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] 農産物・魚介類中における脳血管性認知症予防物質の探索と単離・構造解析2007
- Author(s)
  川原正博,木葉敬子,永田哲也,定金豊
- Organizer
  第24 回微量栄養素研究会シンポジウム
- Place of Presentation
  京都
- Year and Date
  2007-06-07
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] Analysis of alternation of L-Asp residues in recombinant human alpha-crystallin by reversed-phase HPLC.2007
- Author(s)
  Y. Sadakane, K. Konoha, T. Nagata, M. Kawahara, K. Nakagomi, N. Fujii
- Organizer
  3rd D-amino acid research meeting
- Place of Presentation
  Tokushima, Japan
- Year and Date
  2007-09-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] アルミニウムのラット大脳皮質培養神経細胞に対する毒性の化学形態による比較2007
- Author(s)
  木葉敬子, 永田哲也, 定金豊, 川原正博
- Organizer
  第18回日本微量元素学会
- Place of Presentation
  福井
- Year and Date
  2007-07-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Zinc-induced apoptosis of GT1-7 cells are protected by mango(Mangifera indica L.) fruit : a candidate for treatment of neurodegeneration after ischemia.2007
- Author(s)
  M. Kawahara, K. Konoha, T. Nagata, Y. Sadakane
- Organizer
  Neuroscience 2007
- Place of Presentation
  San Diego, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] 農産物・魚介類中における脳血管性認知症予防物質の探索と単離・構造解析2007
- Author(s)
  川原正博, 木葉敬子, 永田哲也, 定金豊
- Organizer
  第24回微量栄養素研究会シンポジウム
- Place of Presentation
  京都
- Year and Date
  2007-06-07
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] Inhibitory activity and mechanisms of carnosine against the zinc-induced neurotoxicity of immortalized hypothalamic neurons.2007
- Author(s)
  Y. Sadakane, K. Konoha, M. Kawahara
- Organizer
  127th Annual Meeting of the Pharmaceutical Society of apan
- Place of Presentation
  Toyama, Japan
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] 亜鉛による培養神経細胞死メカニズムの検討2007
- Author(s)
  木葉敬子、永田哲也、定金豊、川原正博
- Organizer
  第17 回金属の関与する生体関連反応シンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] Purification and structural determination of the suppression substance for cerebrovascular dementia in farm products and seafoods.2007
- Author(s)
  M. Kawahara, K. Konoha, T. Nagata, Y. Sadakane
- Organizer
  24th Symposium of Trace Nutrients Research
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2007-06-07
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] 光反応性Pt-DNAによる結合タンパク質のアフィニティー解析2007
- Author(s)
  友廣岳則, 石原史朗, 神宮寺秀幸, 定金豊, 畑中保丸
- Organizer
  日本薬学会第127年会
- Place of Presentation
  富山
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] アルミニウムのラット大脳皮質培養神経細胞に対する毒性の化学形態による比較2007
- Author(s)
  木葉敬子、定金豊、川原正博
- Organizer
  第18 回日本微量元素学会
- Place of Presentation
  福井
- Data Source
  KAKENHI-PROJECT-19590133
[Presentation] ヒトαB-クリスタリン変異体中のAsp36およびAsp62残基のラセミ化反応速度の解析と構造活性相関2007
- Author(s)
  中村徹, 酒井美世, 定金豊, 芳賀達也, 後藤祐児, 木野内忠稔, 佐藤剛, 藤井紀子
- Organizer
  第3回D-アミノ酸研究会
- Place of Presentation
  徳島
- Year and Date
  2007-09-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Structural comparison of Aluminum-toxicity for rat primary culture cell of cerebral cortex.2007
- Author(s)
  K. Konoha, T. Nagata, Y. Sadakane, M. Kawahara
- Organizer
  18th Japan Society for Biomedical Research on Trace Elements
- Place of Presentation
  Fukui, Japan
- Year and Date
  2007-07-05
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Investigation of the mechanism of zinc-induced neuronal cell death by using citrate.2007
- Author(s)
  Y. Sadakane, K. Konoha, T. Nagata, M. Kawahara
- Organizer
  24th Annual Meeting of Kyushu branch of the Pharmaceutical Society of Japan
- Place of Presentation
  Fukuoka, Japan
- Year and Date
  2007-12-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] L-AspとL-Asn残基の構造変化分析手法の開発:コンフォメーション病に関わるペプチドの分析2006
- Author(s)
  定金豊, 木葉敬子, 川原正博, 中込和哉
- Organizer
  第2回D-アミノ酸研究会
- Place of Presentation
  京都
- Year and Date
  2006-09-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] 亜鉛神経毒性を指標としたスクリーニングによる脳血管性認知症予防物質の探索2006
- Author(s)
  定金豊, 木葉敬子, 川原正博
- Organizer
  第23回日本薬学会九州支部大会
- Place of Presentation
  熊本
- Year and Date
  2006-12-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] 亜鉛神経毒性スクリーニングによる脳血管性認知症予防物質の探索2006
- Author(s)
  木葉敬子, 定金豊, 川原正博
- Organizer
  第23回微量栄養素研究会シンポジウム
- Place of Presentation
  京都
- Year and Date
  2006-06-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Inhibition of neuronal apoptosis by mango fruits-utilization of immature fruit-2006
- Author(s)
  Y. Sadakane, K. Konoha, M. Kawahara
- Organizer
  5th Congress of innovation with Academia, Industry and Government
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2006-06-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Screening of the substances for suppression of cerebrovascular dementia using zinc-induced neuronal degradation.2006
- Author(s)
  K. Konoha, Y. Sadakane, M. Kawahara
- Organizer
  23rd Symposium of Trace Nutrients Research
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2006-06-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Pore formation and distuption of calciumhomeostasis by amyloidogenic peptides including Alzheimer's beta-amyloid protein, prion protein fragment peptide, and alpha-synuclein fragment.2006
- Author(s)
  K. Konoha, Y. Sadakane, M. Kawahara
- Organizer
  The 10th International Conference on Alzheimer's Disease and Related Disorders
- Place of Presentation
  Madrid, Spain
- Year and Date
  2006-07-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] 光反応基ジアジリンを利用した生物学的手法の開発2006
- Author(s)
  定金豊
- Organizer
  第23回日本薬学会九州支部大会
- Place of Presentation
  熊本
- Year and Date
  2006-12-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Analysis of Structural Alternations of L-Asp and L-Asn Residues in Peptides Related to Neuronal Disease2006
- Author(s)
  Y.Sadakane, S.Kumamoto, K.Konoha, M.Kawahara, K.Nakagomi
- Organizer
  43JPS/PEM4
- Place of Presentation
  Yokohama,Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Screening of the substances for suppression of cerebrovascular dementia and analysis for the peptide from seafood.2006
- Author(s)
  K. Konoha, Y. Sadakane, M. Kawahara
- Organizer
  19th Biomedical analytical Science Symposium
- Place of Presentation
  Fukuoka, Japan
- Year and Date
  2006-08-02
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] 海産物由来ペプチドの分析と脳血管性認知症予防物質のスクリーニング2006
- Author(s)
  木葉敬子, 定金豊, 川原正博
- Organizer
  第19回バイオメディカル分析科学シンポジウム
- Place of Presentation
  福岡
- Year and Date
  2006-08-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Screening of suppression substance for cerebrovascular dementia : usefulness of mango fruit and eel.2006
- Author(s)
  Y. Sadakane, K. Konoha, M. Kawahara
- Organizer
  6th OUS Forum 2006
- Place of Presentation
  Okayama, Japan
- Year and Date
  2006-11-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] 光反応基ジアジリンによる分子生物学的手法の開拓2006
- Author(s)
  定金豊, 畑中保丸
- Organizer
  第28回日本光医学・光生物学会
- Place of Presentation
  徳島
- Year and Date
  2006-07-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Analysis of Structural Alternations of L-Asp and L-Asn Residues in Peptides Related to Neuronal Disease.2006
- Author(s)
  Y. Sadakane, S. Kumamoto, K. Konoha, M. Kawahara, K. Nakagomi
- Organizer
  43JPS/PEM4
- Place of Presentation
  Yokohama, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Carnosine protects against zinc-induced apoptosis of GT1-7 cells and cultured rat hippocampal neurons:a candidate for the drugs for neurode generation after ischemia2006
- Author(s)
  K.Konoha, Y.Sadakane, M.Kawahara
- Organizer
  Neuroscience 2006
- Place of Presentation
  Atlanta,USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Development of analytical method for structure alternation of L-Asp and L-Asn : peptides concerned with conformation disease.2006
- Author(s)
  Y. Sadakane, K. Konoha, M. Kawahara, K. Nakagomi
- Organizer
  2nd D-amino acid research meeting
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2006-09-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Analytical method for structure alternation of L-Asp and L-Asn in the peptides concerned with conformation disease.2006
- Author(s)
  Y. Sadakane, K. Konoha, M. Kawahara, K. Nakagomi
- Organizer
  19th Biomedical analytical Science Symposium
- Place of Presentation
  Fukuoka, Japan
- Year and Date
  2006-08-02
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] コンフォメーション病に関わるペプチドでのL-AspとL-Asn残基の構造変化分析手法2006
- Author(s)
  定金豊, 木葉敬子, 川原正博, 中込和哉
- Organizer
  第19回バイオメディカル分析科学シンポジウム
- Place of Presentation
  福岡
- Year and Date
  2006-08-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Pore formation and distuption of calciumhomeostasis by amyloidogenic peptides including Alzheimer's beta-amyloid protein,prion protein fragment peptide,and alpha-synuclein fragment2006
- Author(s)
  K.Konoha, Y.Sadakane, M.Kawahara
- Organizer
  The 10th International Conference on Alzheimer's Disease and Related Disorders
- Place of Presentation
  Madrid,Spain
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] 脳血管性認知症の予防物質の探索:マンゴーとウナギの有用性2006
- Author(s)
  定金豊, 木葉敬子, 川原正博
- Organizer
  第6回OUSフオーラム2006
- Place of Presentation
  岡山
- Year and Date
  2006-11-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Chemical Getaway for Profiling DNA Binding Proteins.2006
- Author(s)
  Y. Hatanaka, Y. Sadakane, T. Takagi, T. Tomohiro
- Organizer
  18th International Symposium on Chemistry, Biology and Medicine
- Place of Presentation
  Cyprus
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Photoaffinity-Based Analysis of Proteins Complexes Related to Cisplatin-Damaged DNA.2006
- Author(s)
  T. Tomohiro, H. Jinguji, F. Ishihara, Y. Sadakane and Y. Hatanaka
- Organizer
  3rd Asian Biological Inorganic Chemistry Conference
- Place of Presentation
  Nanjing, China
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] マンゴー果実抽出液が神経細胞の自殺をくいとめる〜未熟果実の利用法2006
- Author(s)
  定金豊, 木葉敬子, 川原正博
- Organizer
  第5回産学官連携推進会議
- Place of Presentation
  京都
- Year and Date
  2006-06-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Carnosine protects against zinc-induced apoptosis of GT1-7 cells and cultured rat hippocampal neurons : a candidate for the drugs for neurodegeneration after ischemia.2006
- Author(s)
  K. Konoha Y. Sadakane, M. Kawahara
- Organizer
  Neuroscience 2006
- Place of Presentation
  Atlanta, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Screening with zinc-induced neuronal degradation for the substances for suppression of cerebrovascular dementia.2006
- Author(s)
  Y. Sadakane, K. Konoha, M. Kawahara
- Organizer
  23rd Annual Meeting of Kyushu branch of the Pharmaceutical Society of Japan
- Place of Presentation
  Kumamoto, Japan
- Year and Date
  2006-12-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Photoaffinity-Based Analysis of Proteins Complexes Related to Cisplatin-Damaged DNA2006
- Author(s)
  T.Tomohiro, H.Jinguji, F.Ishihara, Y.Sadakane and Y.Hatanaka
- Organizer
  3rd Asian Biological Inorganic Chemistry Conference
- Place of Presentation
  Nanjing,China
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Development of biological methods using photoreactive group, diazirine.2006
- Author(s)
  Y. Sadakane
- Organizer
  23rd Annual Meeting of Kyushu branch of the Pharmaceutical Society of Japan
- Place of Presentation
  Kumamoto, Japan
- Year and Date
  2006-12-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Endeavor for methods in molecular biology with photoreactive group, diazirine.2006
- Author(s)
  Y. Sadakane, Y. Hatanaka
- Organizer
  28th Japan photomedical and photobiology
- Place of Presentation
  Tokushima, Japan
- Year and Date
  2006-07-07
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590114
[Presentation] Chemical Getaway for Profiling DNA Binding Proteins2006
- Author(s)
  Y.Hatanaka, Y.Sadakane, T.Takagi, and T.Tomohiro
- Organizer
  18th International Symposium on Chemistry, Biology and Medicine
- Place of Presentation
  Cyprus
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590114

1. KAWAHARA Masahiro (40224828)

# of Collaborated Projects: 5 results

# of Collaborated Products: 191 results
2. KONOHA Keiko (00369175)

# of Collaborated Projects: 3 results

# of Collaborated Products: 132 results
3. OHTSUKA Isao (20389589)

# of Collaborated Projects: 3 results

# of Collaborated Products: 20 results
4. 畑中保丸 (30111181)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. NAGATA Tetusya (00454992)

# of Collaborated Projects: 1 results

# of Collaborated Products: 41 results
6. FUJII Noriko (90199290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. SUGIYAMA Masaaki (10253395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MORIMOTO Yukio (80200450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KINOUCHI Tadatoshi (90301457)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. SAITO Takeshi (10274143)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KAJI Yuichi (50361332)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SASAKI Horoshi (60260840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. GOTO Yuji (40153770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. KOYAMA Hironari (70567718)

# of Collaborated Projects: 1 results

# of Collaborated Products: 22 results
15. 友廣岳則 (70357581)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 森本正大 (90824772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
17. TANAKA Kenichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 根岸みどり(加藤みどり)

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 齋藤毅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sadakane Yutaka 定金 豊

SADAKANE Yutaka 定金 豊

Research Projects

Research Products

Co-Researchers

Development of photochemical SELEX for efficient screening of DNA aptamers.Principal Investigator

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Efficient separation method for nucleic acid aptamers using photochemical techniquePrincipal Investigator

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Development of photochemical screening for aged proteins in brainPrincipal Investigator

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Development of photochemical cloning for DNA-binding proteinsPrincipal Investigator

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Molecular mechanism of zinc-induced neurotoxicity : involvement of Ca and ER stress

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Mechanism of abnormal protein aggregation and the study of the repair enzyme.

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Development of the photochemical panning adapted to low affinity ligands and analysis of neural carbohydrates' functionsPrincipal Investigator

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Involvement of calcium homeostasis in the apoptotic neuronal death induced by zinc

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Development of screening system for antibody-displayed phages by photo panning method : isolation of anti-amyloid antibodyPrincipal Investigator

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アルツハイマーAβペプチドの新規自己開裂・閉環現象の解明と応用Principal Investigator

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分子認識プロテオミクスを目的とする光キャプチャー法開発

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フォト・パニング法による受容体タンパク質の機能解析Principal Investigator

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Research Institution

受容体の提示発現系と光化学的パニング法の開発Principal Investigator

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Project Period (FY)

Sadakane Yutaka 定金豊

SADAKANE Yutaka 定金豊