MORIGUCHI Kyoko 守口匡子

Researcher Number	60298528
Other IDs
External Links
Affiliation (Current)	2025: 藤田医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 藤田医科大学, 医学部, 准教授 2018 – 2019: 藤田医科大学, 医学部, 講師 2005 – 2017: 藤田保健衛生大学, 医学部, 講師 2002 – 2004: 藤田保健衛生大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Pediatrics / Infectious disease medicine / Hygiene Except Principal Investigator Nanobioscience / Basic Section 54030:Infectious disease medicine-related / Virology
Keywords	Principal Investigator 受動免疫 / ファージ抗体 / 交叉反応性 / ヒト型ファージ抗体 / VP7 / VP4 / 中和抗体 / 組織-血液型抗原 / ヒトノロウイルス / ヒト型抗ノロウイルス抗体 … More / 交差反応性 / 組織・血液型抗原 / 抗ノロウイルス抗体 / 乳酸菌 / ヒト型抗体 / ノロウイルス / passive immunization / Abs expression in L.lactis / neutralizing epitopes / human neutralizing antibodies / cross-reactive / human rotavirus / ヒト型モノクローナル中和抗体 / 交叉応性 / ファージディスプレイ / ヒト型モノクローナル抗体 / ヒトロタウイルス(HRV) / 乳酸菌による抗体発現 / 中和エピトープ / ヒト型中和抗体 / 高叉反応性 / ヒトロタウイルス / 抗原エピトープ / ノロウイルスワクチン / ヒト型抗ノロウイルスファージ抗体 / 抗HuNoV中和抗体 / 抗HuNoVファージ抗体 / ファージ交代 / ヒト型抗ノロウイルス中和交代 / 人工抗体 / 交叉反応性抗体 / ヒト型 / 中和 / 小児感染症学 / HuNov / モノクローナル / HRV / ロタウイルス … More Except Principal Investigator ロタウイルス / バイオセンサ / 血液型抗原 / ノロウイルス / DNAプローブ / ナノ粒子 / 抗体 / 免疫アッセイ / ウイルス / Gastroenteritis / Artificially Infectious Particle / Simian Rotavirus / VP4 gene / Reverse Genetics / Human Rotavirus / キメラウイルス / トリプシン依存性 / リアソートメント / ヒトロタルス / 胃腸炎 / 人工感染粒子 / サルロタウイルス / VP4遺伝子 / リバースジェネテックス / ヒトロタウイルス / 交差反応性抗ノロウイルスファージ抗体 / バイオチップ / 抗体の結晶化 / 交差反応性ノロウイルスファージ抗体 / 時間分解測定 / CMOSイメージセンサ / 蛍光増強 / 表面プラズモン共鳴 Less

ノロウイルス、ロタウイルスによる小腸特異的な感染成立機構の解明
- Principal Investigator
  
  白土東子 (堀越東子)
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  National Institute of Infectious Diseases
External force assisted near-field illumination biosensor system for virus detection in the environment
- Principal Investigator
  
  Fujimaki Makoto
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Nanobioscience
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Development of norovirus detection system utilizing time-resolved fluorescence imaging excited by surface plasmon resonance
- Principal Investigator
  
  FUJIMAKI Makoto
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Nanobioscience
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Development of prophylaxis and therapy in norovirus infection with artificial antibodiesPrincipal Investigator
- Principal Investigator
  
  Moriguchi Kyoko
- Project Period (FY)
  2014 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Fujita Health University
Isolation and characterization of cross-reactive human monoclonal antibodies against human noroviruses.Principal Investigator
- Principal Investigator
  
  MORIGUCHI Kyoko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Fujita Health University
Research and development of therapeutic antibodies against human rotavirus infection.Principal Investigator
- Principal Investigator
  
  MORIGUCHI Kyoko
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Fujita Health University
Isolation, characterization, and application of human monoclonal antibodies that neutralize human rotavirus.Principal Investigator
- Principal Investigator
  
  MORIGUCHI Kyoko
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Fujita Health University
Development of the system for the formation of infectious particles of rotavirus with the aid of genetic engineering
- Principal Investigator
  
  TANIGUCHI Koki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  FUJITA HEALTH UNIVERSITY

All 2019 2017 2016 2015 2014 2013 2012 2011 2010 2004

All Journal Article Presentation

[Journal Article] Detection of norovirus-like particles with an external-force-assisted near-field illumination biosensor2019
- Author(s)
  Masato Yasuura, Haruko Shirato, Kyoko Higo-Moriguchi, Makoto Fujimaki
- Journal Title
  
  Japanese Journal of Applied Physics
  
  Volume: 58 Issue: 7 Pages: 071005-071005
- DOI
  10.7567/1347-4065/ab29e2
- NAID
  210000156402
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01048, KAKENHI-PROJECT-18H01803, KAKENHI-PROJECT-16K09956, KAKENHI-PROJECT-26461516
[Journal Article] Chicken egg yolk abtibodies (IgY) for prophylaxis and treatment of rotavirus diarrhea in human and animal neonates: A concise review2017
- Author(s)
  H. M. Thu, T. W. Myat, M. M. Win, K. Z. Thant, S. Rahman, K. Umeda, S. V. Nguyen, F. C. Icatlo, Jr, K. Higo-Moriguchi, K. Taniguchi, T. Tsuji, K. Oguma, S. J. Kim, H. S. Bae, H. J. Choi
- Journal Title
  
  Korean J. Food Sci. An.
  
  Volume: 37(1) Issue: 1 Pages: 1-9
- DOI
  10.5851/kosfa.2017.37.1.1
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461516
[Journal Article] Oral administration of Bifidobacterium bifidum G9-1 alleviates rotavirus gastroenteritis through regulation of intestinal homeostasis by inducing mucosal protective factors2017
- Author(s)
  Kawahara T, Makizaki Y, Oikawa Y, Tanaka Y, Maeda A, Shimakawa M, Komoto S, Moriguchi K, Ohno H, Taniguchi K
- Journal Title
  
  PLoS One
  
  Volume: 12(3) Issue: 3 Pages: 1-22
- DOI
  10.1371/journal.pone.0173979
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08505, KAKENHI-PROJECT-26461516
[Journal Article] Oral administration of Bifidobacterium bifidum G9-1 alleviates rotavirus gastroenteritis through regulation of intestinal homeostasis by inducing mucosal protective factors2017
- Author(s)
  T. Kawahara, Y. Makizaki, Y. Oikawa, Y. Tanaka, A. Maeda, M. Shimakawa, S. Komoto, K. Moriguchi, H. Ohno, K. Taniguchi
- Journal Title
  
  PLOS one
  
  Volume: 27 Pages: 1-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461516
[Journal Article] Detection of norovirus virus-like particles using a surface plasmon resonance-assisted fluoroimmunosensor optimized for quantum dot fluorescent labels2017
- Author(s)
  H. Ashiba, Y. Sugiyama, X. Wang, H. Shirato, K. Moriguchi, K. Taniguchi, Y. Ohki, M. Fujimaki
- Journal Title
  
  Biosensors and Bioelectronics
  
  Volume: 93 Pages: 260-266
- DOI
  10.1016/j.bios.2016.08.099
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26246008, KAKENHI-PROJECT-16K09956
[Journal Article] High Prevalence of G12 Human Rotaviruses in Children with Gastroenteritis in Myanmar2016
- Author(s)
  Ide T, Higo-Moriguchi K, Komoto S, Htun KW, Myint YY, Myat TW, Thant KZ, Thu HM, Win MM, Oo HN, Htut T, Rahman S, Nguyen SV, Umeda K, Oguma K, Tsuji T, Taniguchi K.
- Journal Title
  
  Jpn J Infect Dis
  
  Volume: 69 Issue: 4 Pages: 326-327
- DOI
  10.7883/yoken.JJID.2015.267
- NAID
  130005165482
- ISSN
  1344-6304, 1884-2836
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08505, KAKENHI-PROJECT-26461516
[Journal Article] Whole genomic analysis of human G12P[6] and G12P[8] rotavirus strains that have emerged in Myanmar.2015
- Author(s)
  Ide T, Komoto S, Higo-Moriguchi K, Htun KW, Myint YY, Myat TW, Thant KZ, Thu HM, Win MM, Oo HN, Htut T, Wakuda M, Dennis FE, Haga K, Fujii Y, Katayama K, Rahman S, Nguyen SV, Umeda K, Oguma K, Tsuji T, Taniguchi K.
- Journal Title
  
  PLoS ONE
  
  Volume: 10 Issue: 5 Pages: 1-24
- DOI
  10.1371/journal.pone.0124965
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590561, KAKENHI-PROJECT-24790454, KAKENHI-PROJECT-15K08505, KAKENHI-PROJECT-26461516
[Journal Article] Isolation of cross-reactive human monoclonal antibodies that prevent binding of human noroviruses to histo-blood group antigen.2014
- Author(s)
  K. HIGO-MORIGUCHI, H. Shirato, Y. Someya, Y. Kurosawa, N. Takeda, and K. Taniguchi
- Journal Title
  
  Journal od Medical Virology
  
  Volume: 86 Issue: 4 Pages: 558-567
- DOI
  10.1002/jmv.23734
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659338, KAKENHI-PROJECT-25461528
[Journal Article] Randomized placebo-controlled clinical trial of immunoglobulin Y as adjunct to standard supportive therapy for rotavirus-associated diarrhea.2012
- Author(s)
  Shofiqur Rahman, Kyoko Higo-Moriguchi, 他15名
- Journal Title
  
  Vaccine
  
  Volume: 30 Pages: 4661-4669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659338
[Journal Article] Randomized placebo-controlled clinical trial of immunoglobulin Y as adjunct to standard supportive therapy for rotavirus-associated diarrhea2012
- Author(s)
  S. Rahman, K. Higo-Moriguchi, et al
- Journal Title
  
  Vaccine
  
  Volume: 30 Pages: 4661-4669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659338
[Journal Article] Isolation of human monoclonal antibodies neutralizing human rotaviruses.2004
- Author(s)
  Higo-Moriguchi K, Akahori Y, Iba Y, Kurosawa Y, Taniguchi K
- Journal Title
  
  J Virol 78(4)
  
  Pages: 3325-3332
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370105
[Journal Article] Isolation of human monoclonal antibodies neutralizing human rotaviruses.2004
- Author(s)
  Higo-Moriguchi et al.
- Journal Title
  
  Journal of Virology 78
  
  Pages: 3325-3332
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370105
[Journal Article] Isolation of human monoclonal antibodies that neutralize human rotavirus2004
- Author(s)
  Kyoko Higo-Moriguchi
- Journal Title
  
  Journal of Virology Vol. 78
  
  Pages: 3325-3325
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591064
[Journal Article] Isolation of human monoclonal antibodies neutralizing human rotaviruses.2004
- Author(s)
  Higo-Moriguchi K et al.
- Journal Title
  
  Journal of Virology 78・7
  
  Pages: 3325-3332
- Data Source
  KAKENHI-PROJECT-14370105
[Journal Article] Isolation of human monoclonal antibodies that neutralize human rotavirus2004
- Author(s)
  Kyoko Higo-Moriguchi
- Journal Title
  
  Journal of virology 78(7)
  
  Pages: 3325-3332
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591064
[Presentation] 外力支援近接場照明バイオセンサによる実環境サンプル測定2017
- Author(s)
  安浦雅人、白土東子、守口匡子、藤巻真
- Organizer
  第78回応用物理学会秋季学術講演会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01048
[Presentation] EFA-NIバイオセンサを用いた実環境サンプル中のノロウイルス様粒子検出2017
- Author(s)
  安浦雅人、白土東子、守口匡子、藤巻真
- Organizer
  ケミカルセンサ研究会
- Data Source
  KAKENHI-PROJECT-17H01048
[Presentation] ヒト型抗ノロウイルス抗体のウイルス-血液型抗原吸着阻害活性の検討2013
- Author(s)
  染谷雄一、守口匡子、白土東子、奥野良信、黒澤良和、武田直和、谷口孝喜
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659338
[Presentation] ファージディスプレイ法により単離したヒト型抗ノロウイルス抗体の、ウイルス-血液型抗原吸着阻害活性の検討2012
- Author(s)
  守口匡子、白土東子、染谷雄一、武田直和、奥野良信、黒澤良和、谷口孝喜
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23659338
[Presentation] ファージディスプレイ法により単離したヒト型抗ノロウイルス抗体の,ウイルス‐血液型高原吸着阻害活性の検討2012
- Author(s)
  守口匡子,白土東子,染谷雄一,武田直和,奥野良信,黒澤良和,谷口孝喜
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23659338
[Presentation] Randomized placebo-controlled clinical trial of immunoglobulin Y as adjunct to standard supportive therapy for rotavirus-associated diarrhea among pediatric patients2012
- Author(s)
  Rahaman S,Higo-Moriguchi K, Htun K W,Taniguchi K, Icatlio FC, Tsuji T, Kodama Y, Nguyen SV, Umeda K, Oo HN, Myint YY, Htut T, Myint SS, Thura K, Thu HM, Fatmawati NND, Ogyma K
- Organizer
  46th Joint Working Conference on Viral Diseases, The Japan-United States Cooperative Medical Science Program
- Place of Presentation
  Japan (Sapporo)
- Data Source
  KAKENHI-PROJECT-23659338
[Presentation] 交叉反応性ヒト型抗ヒトノロウイルス抗体の単離2011
- Author(s)
  守口匡子、白土東子、染谷雄一、奥野良信、黒澤良和、谷口孝喜
- Organizer
  国際ウイルス学会議
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659338
[Presentation] Isolation of cross-reactive human monoclonal antibodies against human norovirus2011
- Author(s)
  Higo-Moriguchi K, Horikoshi-Shirato H, Someya Y, Okuno Y, Kurosawa Y, Taniguchi K
- Organizer
  XV International Congress of Virology
- Place of Presentation
  Japan
- Data Source
  KAKENHI-PROJECT-23659338
[Presentation] ファージディスプレイ法による広域遺伝子型反応性ヒト型抗ノロウイルス抗体の単離2011
- Author(s)
  守口匡子、白土東子、染谷雄一、奥野良信、黒澤良和、谷口孝喜
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-19591266
[Presentation] ファージディスプレイ法による、ヒト型抗ノロウイルス抗体の単離2010
- Author(s)
  守口匡子
- Organizer
  第58回日本ウイルス学会学術集会
- Place of Presentation
  あわぎんホール(徳島)
- Year and Date
  2010-11-07
- Data Source
  KAKENHI-PROJECT-19591266
[Presentation] ファージディスプレイ法による、ヒト型抗ノロウイルス抗体の単離2010
- Author(s)
  守口匡子、白土東子、染谷雄一、奥野良信、黒澤良和、谷口孝喜
- Organizer
  第58回日本ウイルス学会学術集会
- Place of Presentation
  徳島
- Year and Date
  2010-01-17
- Data Source
  KAKENHI-PROJECT-19591266

1. TANIGUCH Ikoki (40094213)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
2. 白土東子 (60356243)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
3. FUJIMAKI Makoto (10392656)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. 久保田智巳 (90356923)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KAWAHITO Shoji (40204763)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SASAKI Jun (70319268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MAENO Yoshimasa (70131191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 香川景一郎 (30335484)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 染谷雄一 (50283809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 芦葉裕樹 (90712216)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 島隆之 (10371048)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 藤岡貴浩 (20759691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 宮沢孝幸 (80282705)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 河本聡志 (60367711)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

MORIGUCHI Kyoko 守口 匡子

Research Projects

Research Products

Co-Researchers

ノロウイルス、ロタウイルスによる小腸特異的な感染成立機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

External force assisted near-field illumination biosensor system for virus detection in the environment

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of norovirus detection system utilizing time-resolved fluorescence imaging excited by surface plasmon resonance

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of prophylaxis and therapy in norovirus infection with artificial antibodiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Isolation and characterization of cross-reactive human monoclonal antibodies against human noroviruses.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research and development of therapeutic antibodies against human rotavirus infection.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Isolation, characterization, and application of human monoclonal antibodies that neutralize human rotavirus.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the system for the formation of infectious particles of rotavirus with the aid of genetic engineering

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Detection of norovirus-like particles with an external-force-assisted near-field illumination biosensor2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Chicken egg yolk abtibodies (IgY) for prophylaxis and treatment of rotavirus diarrhea in human and animal neonates: A concise review2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oral administration of Bifidobacterium bifidum G9-1 alleviates rotavirus gastroenteritis through regulation of intestinal homeostasis by inducing mucosal protective factors2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oral administration of Bifidobacterium bifidum G9-1 alleviates rotavirus gastroenteritis through regulation of intestinal homeostasis by inducing mucosal protective factors2017

Author(s)

Journal Title

Data Source

[Journal Article] Detection of norovirus virus-like particles using a surface plasmon resonance-assisted fluoroimmunosensor optimized for quantum dot fluorescent labels2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High Prevalence of G12 Human Rotaviruses in Children with Gastroenteritis in Myanmar2016

Author(s)

Journal Title

MORIGUCHI Kyoko 守口匡子