SHINOJIMA TOSHIAKI 篠島利明

… Alternative Names

SHINOJIMA Toshiaki 篠島利明

篠島利明シノジマトシアキ

Less

Researcher Number	60306777
Other IDs
Affiliation (Current)	2025: 埼玉医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2022: 慶應義塾大学, 医学部(信濃町), 講師 2019 – 2020: 慶應義塾大学, 医学部(信濃町), 講師(非常勤) 2016 – 2018: 慶應義塾大学, 医学部(信濃町), 講師 2015: 慶應義塾大学, 医学部, 助教 2004 – 2005: 慶應義塾大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 56030:Urology-related Except Principal Investigator Urology / Basic Section 56030:Urology-related
Keywords	Principal Investigator 癌関連遺伝子 / HIF-2α / CD68 / PBRM1 / クロマチンリモデリング / ヒストン修飾 / エピジェネシス / 腫瘍免疫 / 遺伝子変異 / エピジェネティクス / 腎細胞癌 … More Except Principal Investigator … More 分子標的治療 / 腎細胞癌 / 耐性 / 血管新生 / 癌 / 免疫チェックポイント阻害薬 / DHMEQ / 免疫治療 / マウス動物モデル / 巨大尿管 / 非侵襲的診断法 / 小児泌尿器疾患 / 先天性腎尿路異常 / 尿路感染症 / カラードプラ法超音波検査 / 腎瘢痕 / 逆流性腎症 / 膀胱尿管逆流 / バイオマーカー / 血清遊離DNA / 遊離DNA / リスク分類 / 治療抵抗性 / Acute rejection / Ischemia-reperfusion injury / Transplantation / 急性拒絶反応 / 虚血再灌流障害 / 移植 Less

Aberrant histone modification patterns of tumor-related gene promoter as a new biomarker for renal cell carcinomaPrincipal Investigator
- Principal Investigator
  
  SHINOJIMA Toshiaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Keio University
Establishment of novel noninvasive diagnostic modality for vesicoureteral reflux using color Doppler ultrasonography
- Principal Investigator
  
  ASANUMA Hiroshi
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Keio University
Development of novel therapeutic modality by integrated analysis of immune environment of renal cell carcinoma and remodeling after inhibition of angiogenesis
- Principal Investigator
  
  OYA Mototsugu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Keio University
Utility of liquid biopsy for metastatic renal cell carcinoma
- Principal Investigator
  
  Ryuichi MIZUNO
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Keio University
Elucidation of refractory mechanism to the molecular targeted therapy for renal cell carcinoma
- Principal Investigator
  
  Oya Mototsugu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Keio University
Anew strategy utilizing a novel NF-κB inhibitor for renal allograft rejection.
- Principal Investigator
  
  NAKAGAWA Ken
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Keio University

All 2019 2018 2017 2016 2015 2014

All Journal Article Presentation

[Journal Article] Individualized Dosing of Axitinib Based on First-Dose Area Under the Concentration?Time Curve for Metastatic Renal-Cell Carcinoma2019
- Author(s)
  Miura Yuji、Imamura Chiyo K.、Uchino Keita、Kishida Takeshi、Matsubara Nobuaki、Shinojima Toshiaki、Kondo Keiichi、Hongo Fumiya、Yoshimura Kenichi、Tanigawara Yusuke、Takano Toshimi
- Journal Title
  
  Clinical Genitourinary Cancer
  
  Volume: 17 Issue: 1 Pages: e1-e11
- DOI
  10.1016/j.clgc.2018.09.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09150
[Journal Article] Prognostic value of serum C-reactive protein level prior to second-line treatment in intermediate risk metastatic renal cell carcinoma patients2019
- Author(s)
  Kimiharu Takamatsu, Ryuichi Mizuno, Nobuyuki Tanaka, Toshikazu Takeda, Shinya Morita, Kazuhiro Matsumoto, Takeo Kosaka, Toshiaki Shinojima, Eiji Kikuchi, Hiroshi Asanuma, Masafumi Oyama, Shuji Mikami, Mototsugu Oya
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 24 Issue: 9 Pages: 1069-1074
- DOI
  10.1007/s10147-019-01459-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09150, KAKENHI-PROJECT-18H02939, KAKENHI-PROJECT-17K11159
[Journal Article] Factors affecting renal function preservation among patients not achieving trifecta after laparoscopic partial nephrectomy for clinical T1a renal masses2019
- Author(s)
  Takeda Toshikazu、Komatsuda Akari、Yanai Yoshinori、Tanaka Nobuyuki、Matsumoto Kazuhiro、Morita Shinya、Kosaka Takeo、Mizuno Ryuichi、Shinojima Toshiaki、Asanuma Hiroshi、Oya Mototsugu
- Journal Title
  
  Asian Journal of Endoscopic Surgery
  
  Volume: － Issue: 4 Pages: 526-531
- DOI
  10.1111/ases.12776
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02939
[Journal Article] Prognostic Value of Baseline Serum C-Reactive Protein Level in Intermediate-Risk Group Patients With Metastatic Renal-Cell Carcinoma Treated by First-Line Vascular Endothelial Growth Factor-Targeted Therapy.2018
- Author(s)
  Takamatsu K1, Mizuno R2, Omura M1, Morita S1, Matsumoto K1, Shinoda K1, Kosaka T1, Takeda T1, Shinojima T1, Kikuchi E1, Asanuma H1, Oyama M3, Mikami S4, Oya M1.
- Journal Title
  
  Clin Genitourin Cancer
  
  Volume: 16（4） Issue: 4 Pages: e927-e933
- DOI
  10.1016/j.clgc.2018.03.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11159, KAKENHI-PROJECT-18K09150, KAKENHI-PROJECT-18H02939
[Journal Article] Impact of baseline visceral fat accumulation on prognosis in patients with metastatic renal cell carcinoma treated with systemic therapy.2017
- Author(s)
  Mizuno R, Miyajima A, Hibi T, Masuda A, Shinojima T, Kikuchi E, Jinzaki M, Oya M
- Journal Title
  
  Med Oncol.
  
  Volume: 34(4) Issue: 4 Pages: 47-47
- DOI
  10.1007/s12032-017-0908-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04977
[Journal Article] Baseline risk stratification or duration of prior therapy predicts prognosis in patients with metastatic renal cell carcinoma treated with axitinib.2017
- Author(s)
  Mizuno R, Mikami S, Takamatsu K, Shinojima T, Kikuchi E, Oya M
- Journal Title
  
  Clin Oncol.
  
  Volume: 47(12) Issue: 12 Pages: 1170-1174
- DOI
  10.1093/jjco/hyx134
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04977
[Journal Article] Activation of aryl hydrocarbon receptor promotes invasion of clear cell renal cell carcinoma and is associated with poor prognosis and cigarette smoke.2014
- Author(s)
  Ishida M, Mikami S, Shinojima T, Kosaka T, Mizuno R, Kikuchi E, Miyajima A, Okada Y, Oya M
- Journal Title
  
  Int J Cancer
  
  Volume: Epub ahead of print Issue: 2 Pages: 299-310
- DOI
  10.1002/ijc.29398
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390374, KAKENHI-PROJECT-15H04977
[Presentation] AYA世代になって治療介入を要した先天性腎尿路異常（CAKUT）の臨床的検討2019
- Author(s)
  寺西　悠、浅沼　宏、田中伸之、武田利和、松本一宏、森田伸也、小坂威雄、水野隆一、篠島利明、菊地栄次、大家基嗣
- Organizer
  第16回泌尿器科再建再生研究会
- Data Source
  KAKENHI-PROJECT-18K09207
[Presentation] 閉塞性巨大尿管症に対してpsoas-hitch法による尿管膀胱新吻合術を施行した成人症例2018
- Author(s)
  寺西　悠、浅沼　宏、田中伸之、武田利和、松本一宏、森田伸也、小坂威雄、水野隆一、篠島利明、菊地栄次、大家基嗣
- Organizer
  第15回泌尿器科再建再生研究会
- Data Source
  KAKENHI-PROJECT-18K09207
[Presentation] 転移性腎細胞癌に対するニボルマブの効果予測因子の検討2018
- Author(s)
  108.高松公晴、水野隆一、田中伸之、武田利和、森田伸也、松本一宏、小坂威雄、篠島利明、菊地栄次、浅沼宏、三上修治、大家基嗣
- Organizer
  第56回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09150
[Presentation] ニボルマブ関連間質性肺炎に対してステロイドが有効であった転移性腎細胞癌の1例2017
- Author(s)
  岩佐俊、水野隆一、寺西悠、森田伸也、篠田和伸、小坂威雄、篠島利明、菊地栄次、浅沼宏、秋田大宇、陣崎雅弘、額賀重成、大家基嗣
- Organizer
  第82回日本泌尿器科学会東部総会
- Data Source
  KAKENHI-PROJECT-15H04977
[Presentation] 血管新生阻害薬に対して初期耐性を示した進行性腎細胞癌症例の特徴2017
- Author(s)
  篠島利明、水野隆一、松本一宏、森田伸也、篠田和伸、小坂威雄、菊地栄次、浅沼宏、宮嶋哲、大家基嗣
- Organizer
  第105回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-15H04977
[Presentation] 当院における腹腔鏡下副腎部分切除術の術式確立の試み2017
- Author(s)
  勝井政博、宮嶋哲、森田伸也、松本一宏、篠田和伸、小坂威雄、水野隆一、篠島利明、菊地栄次、浅沼宏、大家基嗣
- Organizer
  第105回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-15H04977
[Presentation] 血管新生阻害薬に対して内因性耐性を示した進行性腎細胞癌症例の転帰2016
- Author(s)
  篠島利明、水野隆一、松本一宏、森田伸也、篠田和伸、小坂威雄、菊地栄次、浅沼宏、宮嶋哲、大家基嗣
- Organizer
  第104回日本泌尿器科学会総会
- Place of Presentation
  仙台国際センター（仙台市青葉区）
- Year and Date
  2016-04-23
- Data Source
  KAKENHI-PROJECT-15H04977
[Presentation] Plasma fibrinogen level independently predicts the prognosis of patients with non-metastatic renal cell carcinoma2015
- Author(s)
  Obata J, Tanaka N, Mizuno R, Morita S, Shinoda K, Kosaka T, Shinojima T, Kikuchi E, Asanuma H, Miyajima A, Oya M
- Organizer
  The 110th American Urological Association Annual Meeting
- Place of Presentation
  ニューオーリンズ（アメリカ）
- Year and Date
  2015-05-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04977
[Presentation] Predictors of renal dysfunction during everolimus treatment in patients with metastatic renal cell carcinoma2015
- Author(s)
  Mizuno R, Takahashi R, Shinojima T, Kosaka T, Miyajima A, Oya M
- Organizer
  2015 ASCO Annual Meeting
- Place of Presentation
  シカゴ（アメリカ）
- Year and Date
  2015-05-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04977

1. Ryuichi MIZUNO (60383824)

# of Collaborated Projects: 5 results

# of Collaborated Products: 15 results
2. Oya Mototsugu (00213885)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
3. ASANUMA Hiroshi (70245570)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
4. 三上修治 (20338180)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
5. MIYAJIMA Akira (90245572)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 菊地栄次 (10286552)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
7. 小坂威雄 (30445407)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
8. NAKAGAWA Ken (50227740)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KOUNO Hidaka (50338133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MURAI Masaru (90101956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 田中伸之 (60445244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 宮島哲

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results

SHINOJIMA TOSHIAKI 篠島 利明

SHINOJIMA Toshiaki 篠島 利明

篠島 利明 シノジマ トシアキ

Research Projects

Research Products

Co-Researchers

Aberrant histone modification patterns of tumor-related gene promoter as a new biomarker for renal cell carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of novel noninvasive diagnostic modality for vesicoureteral reflux using color Doppler ultrasonography

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel therapeutic modality by integrated analysis of immune environment of renal cell carcinoma and remodeling after inhibition of angiogenesis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Utility of liquid biopsy for metastatic renal cell carcinoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of refractory mechanism to the molecular targeted therapy for renal cell carcinoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Anew strategy utilizing a novel NF-κB inhibitor for renal allograft rejection.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Individualized Dosing of Axitinib Based on First-Dose Area Under the Concentration?Time Curve for Metastatic Renal-Cell Carcinoma2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic value of serum C-reactive protein level prior to second-line treatment in intermediate risk metastatic renal cell carcinoma patients2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Factors affecting renal function preservation among patients not achieving trifecta after laparoscopic partial nephrectomy for clinical T1a renal masses2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic Value of Baseline Serum C-Reactive Protein Level in Intermediate-Risk Group Patients With Metastatic Renal-Cell Carcinoma Treated by First-Line Vascular Endothelial Growth Factor-Targeted Therapy.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of baseline visceral fat accumulation on prognosis in patients with metastatic renal cell carcinoma treated with systemic therapy.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Baseline risk stratification or duration of prior therapy predicts prognosis in patients with metastatic renal cell carcinoma treated with axitinib.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Activation of aryl hydrocarbon receptor promotes invasion of clear cell renal cell carcinoma and is associated with poor prognosis and cigarette smoke.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] AYA世代になって治療介入を要した先天性腎尿路異常（CAKUT）の臨床的検討2019

Author(s)

Organizer

SHINOJIMA TOSHIAKI 篠島利明

SHINOJIMA Toshiaki 篠島利明

篠島利明シノジマトシアキ