Nishi Hirotaka 西洋孝

… Alternative Names

NISHI Hirotaka 西洋孝

西洋孝ニシヒロタカ

Less

Researcher Number	60307345
Other IDs
Affiliation (Current)	2025: 東京医科大学, 医学部, 主任教授
Affiliation (based on the past Project Information) *help	2018 – 2023: 東京医科大学, 医学部, 主任教授 2017: 東京医科大学, 医学部, 教授 2009 – 2016: 東京医科大学, 医学部, 講師 2011: 東京医科大学, 産科婦人科, 講師 2002 – 2005: 東京医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology
Keywords	Principal Investigator 腫瘍マーカー / miRNA / 子宮体癌 / 明細胞線癌 / 明細胞癌 / 卵巣癌 / 子宮頸がん / microRNA / 子宮頸癌 / estrogen receptor … More / estrogen / MMP / TERT / テロメラーゼ / TGF-β3 / HIF-1 / 妊娠中毒症 / 低酸素 / 胎盤 / hTERT promoter / preeclampsia / trophoblast / placenta / hypoxia … More Except Principal Investigator 時間生物学 / 雌性生殖器官 / 時計遺伝子 / 子宮筋腫 / 卵巣 / 生殖内分泌 / 生殖 / 概日時計 / 性ステロイド / 不妊症 / 顆粒膜細胞 / 概日リズム / ESR1 / 子宮頸癌予防 / 子宮頸癌 / MACROD1 / CIN / WAPL / テーラーメード医療 / 薬剤耐性 / パクリタキセル / 子宮体がん / 卵巣がん / 薬学 / 遺伝子 / 癌 Less

Application of chronobiology to uterine leiomyomas and infertility
- Principal Investigator
  
  小野政徳
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Tokyo Medical University
Development of a Novel Preventive Method for Cervical Cancer
- Principal Investigator
  
  Kumagai Katsuyoshi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  University of Human Arts and Sciences
  Tokyo Medical University
Profiling analysis of circulating microRNA expression in endometrial cancerPrincipal Investigator
- Principal Investigator
  
  Nishi Hirotaka
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Tokyo Medical University
Identification and analysis of circulating miRNAs in Ovarian clear cell carcinomaPrincipal Investigator
- Principal Investigator
  
  NISHI HIROTAKA
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tokyo Medical University
Identification and analysis of circulating miRNAs in cervical cancerPrincipal Investigator
- Principal Investigator
  
  NISHI HIROTAKA
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tokyo Medical University
Personalized medicine using newly identified paclitaxel-sensitive genes in gynecologic cancer
- Principal Investigator
  
  ISAKA Keiichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tokyo Medical University
子宮内膜におけるMMP-26の発現とそのメカニズム解析Principal Investigator
- Principal Investigator
  
  西洋孝
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tokyo Medical University
低酸素によるトロホブラストの増殖能亢進および分化・浸潤能消失のメカニズム解析Principal Investigator
- Principal Investigator
  
  西洋孝
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tokyo Medical University

All 2023 2021 2018 2016 2015 2014 2013 2012 2011 2009 Other

All Journal Article Presentation

[Journal Article] Sirtuin 1 is a potential therapeutic candidate gene for fetal growth restriction via insulin-like 42023
- Author(s)
  Kojima Junya、Dai Yidan、Suzuki Tomoo、Ono Masanori、Nishi Hirotaka
- Journal Title
  
  The Journal of Maternal-Fetal & Neonatal Medicine
  
  Volume: 36 Issue: 2 Pages: 1-8
- DOI
  10.1080/14767058.2023.2253486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16866, KAKENHI-PROJECT-22K09556
[Journal Article] BMAL1 positively correlates with genes regulating steroidogenesis in human luteinized granulosa cells2023
- Author(s)
  Kawamura Tomomi、Dai Yidan、Ono Masanori、Kikuchi Takayuki、Yamanaka Akina、Ueno Keiko、Kojima Junya、Fujiwara Tomoko、Daikoku Takiko、Maida Yoshiko、Ando Hitoshi、Fujiwara Hiroshi、Kuji Naoaki、Nishi Hirotaka
- Journal Title
  
  Reproduction
  
  Volume: 167 Issue: 2
- DOI
  10.1530/rep-23-0225
- Data Source
  KAKENHI-PROJECT-22K09556
[Journal Article] The Long-Term Outcome of Children Conceived Through Assisted Reproductive Technology2023
- Author(s)
  Ono Masanori、Kuji Naoaki、Ueno Keiko、Kojima Junya、Nishi Hirotaka
- Journal Title
  
  Reproductive Sciences
  
  Volume: 31 Issue: 3 Pages: 583-590
- DOI
  10.1007/s43032-023-01339-0
- Data Source
  KAKENHI-PROJECT-22K09556
[Journal Article] The Circadian Clock, Nutritional Signals and Reproduction: A Close Relationship2023
- Author(s)
  Ono Masanori、Ando Hitoshi、Daikoku Takiko、Fujiwara Tomoko、Mieda Michihiro、Mizumoto Yasunari、Iizuka Takashi、Kagami Kyosuke、Hosono Takashi、Nomura Satoshi、Toyoda Natsumi、Sekizuka-Kagami Naomi、Maida Yoshiko、Kuji Naoaki、Nishi Hirotaka、Fujiwara Hiroshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 2 Pages: 1545-1545
- DOI
  10.3390/ijms24021545
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K10820, KAKENHI-PROJECT-22K09556, KAKENHI-PROJECT-19K09776
[Journal Article] WAPL induces cervical intraepithelial neoplasia modulated with estrogen signaling without HPV E6/E7. Oncogene.2021
- Author(s)
  Kumagai K, Takanashi M, Ohno SI, Harada Y, Fujita K, Oikawa K, Sudo K, Ikeda　SI, Nishi H, Oikawa K, Kuroda M.
- Journal Title
  
  Oncogene
  
  Volume: 40(21) Issue: 21 Pages: 3695-3706
- DOI
  10.1038/s41388-021-01787-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08382, KAKENHI-PROJECT-21H02706, KAKENHI-PROJECT-20K09654
[Journal Article] Profiling analysis of circulating microRNA expression in cervical cancer2016
- Author(s)
  Nagamitsu Y, Nishi H, Sasaki T, Takaesu Y, Terauchi F, Isaka K
- Journal Title
  
  MOLECULAR AND CLINICAL ONCOLOGY
  
  Volume: 5 Issue: 1 Pages: 189-194
- DOI
  10.3892/mco.2016.875
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592533
[Journal Article] Identification of a novel role of Septin 10 in Paclitaxel-resistance in cancers through a functional genomics screen2012
- Author(s)
  Xu M, Takanashi M, Oikawa K, Nishi H, Isaka K, Yoshimoto T, Ohyashiki J, Kuroda M
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Issue: 4 Pages: 821-827
- DOI
  10.1111/j.1349-7006.2012.02221.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592146, KAKENHI-PROJECT-22590367, KAKENHI-PROJECT-23390087, KAKENHI-PROJECT-23590417, KAKENHI-PROJECT-23590475, KAKENHI-PROJECT-23590993, KAKENHI-PROJECT-23659192, KAKENHI-PROJECT-23659626, KAKENHI-PROJECT-24370058
[Journal Article] USP15 plays an essential role for caspase-3 activation during Paclitaxel-induced apoptosis2009
- Author(s)
  Xu M, Takanashi M, Oikawa K, Tanaka M, Nishi H, Isaka K, Kudo M, Kuroda M.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 388 Pages: 366-371
- URL
  http://www.sciencedirect.com/science/article/pii/S0006291X09015678
- Data Source
  KAKENHI-PROJECT-21592146
[Presentation] 婦人科癌における腫瘍マーカーとしての血清中マイクロRNA - 1滴の血液による診断 -2018
- Author(s)
  西　洋孝
- Organizer
  横浜市産婦人科医会月例研究会
- Invited
- Data Source
  KAKENHI-PROJECT-15K10733
[Presentation] 子宮頸癌の血清miR-100は早期発見のマーカーとなりうる2015
- Author(s)
  加藤利奈、西　洋孝、永光雄造、佐々木徹、井坂惠一
- Organizer
  第53回日本癌治療学会学術集会
- Place of Presentation
  京都市
- Year and Date
  2015-10-29
- Data Source
  KAKENHI-PROJECT-24592533
[Presentation] miR-100 mediates resistance to paclitaxel in cervical cancer cells2014
- Author(s)
  Rina Kato, Hirotaka Nishi, Yuzo Nagamitsu, Toru Sasaki, Keiichi Isaka
- Organizer
  AACR Annual Meeting 2014
- Place of Presentation
  San Diego
- Year and Date
  2014-04-08
- Data Source
  KAKENHI-PROJECT-24592533
[Presentation] 子宮頸がんにおいて低酸素がmiR-100を亢進し，USP15を抑制することによりパクリタキセル耐性を示す2013
- Author(s)
  西洋孝、井坂惠一
- Organizer
  第65回日本産科婦人科学会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24592533
[Presentation] 子宮頸がんにおいて血清中miR-100の発現は抑制されている2013
- Author(s)
  西洋孝、永光雄造、佐々木徹、井坂惠一
- Organizer
  第 1 回婦人科がんバイオマーカー研究会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24592533
[Presentation] Exosomal-miRNA profiles as diagnostic biomarkers in cervical cancer2012
- Author(s)
  Hirotaka Nishi, Yuzo Nagamitsu, Toru Sasaki, Yotaro Takaesu, Fumitoshi Terauchi, Keiichi Isaka
- Organizer
  ASCO Annual Meeting
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-24592533
[Presentation] 子宮頸がんにおける血清中miRNAのプロファイリング解析2012
- Author(s)
  永光雄造、西　洋孝、佐々木徹、高江洲陽太郎、中山大栄、佐川泰一、寺内文敏、井坂惠一
- Organizer
  第64回日本産科婦人科学会学術講演会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24592533
[Presentation] Genetic diagnosis for chemosensitivity with paclitaxel-sensitive genes in epithelial ovarian cancer2011
- Author(s)
  Hirotaka Nishi
- Organizer
  16^<th> World Congress on Advances in Oncology
- Place of Presentation
  Rhodes Island, Greece
- Data Source
  KAKENHI-PROJECT-21592146
[Presentation] A functional genomic screen identifies a role of USP15 and Septin 10 in spindle-checkpoint and Paclitaxel-resistance in human cancers2009
- Author(s)
  Mingli Xu, Masakatsu Takanashi, Kosuke Oikawa, Masami Tanaka, Hirotaka Nishi, Keiichi Isaka, Motoshige Kudo and Masahiko Kuroda
- Organizer
  AACR Annual Meeting 2009
- Place of Presentation
  Denver, CO, Abstrac
- Data Source
  KAKENHI-PROJECT-21592146
[Presentation] Genetic diagnosis for chemosensitivity with paclitaxel-sensitive genes in epithelial ovarian cancer
- Author(s)
  Hirotaka Nishi, Toru Sasaki, Yotaro Takaesu, Yuzo Nagamitsu, Chinatsu Higuma, Fumitoshi Terauchi, Masahiko Kuroda, Keiichi Isaka
- Organizer
  16th World Congress on Advances in Oncology
- Place of Presentation
  Rhodes, Greece
- Data Source
  KAKENHI-PROJECT-21592146

1. ISAKA Keiichi (10201310)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. KURODA Masahiko (80251304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. Kumagai Katsuyoshi (20567911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 岡本愛光 (20204026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 山中善太 (30816757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 須藤カツ子 (50126091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 高梨正勝 (80312007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 原田裕一郎 (80570168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 大野慎一郎 (90513680)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 小野政徳 (70348712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 藤原浩 (30252456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 大黒多希子 (30767249)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 安藤仁 (50382875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 藤原智子 (60310744)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 久慈直昭 (80169987)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. 小島淳哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 関塚真美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 毎田佳子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nishi Hirotaka 西 洋孝

NISHI Hirotaka 西 洋孝

西 洋孝 ニシ ヒロタカ

Research Projects

Research Products

Co-Researchers

Application of chronobiology to uterine leiomyomas and infertility

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a Novel Preventive Method for Cervical Cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Profiling analysis of circulating microRNA expression in endometrial cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification and analysis of circulating miRNAs in Ovarian clear cell carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification and analysis of circulating miRNAs in cervical cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Personalized medicine using newly identified paclitaxel-sensitive genes in gynecologic cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

子宮内膜におけるMMP-26の発現とそのメカニズム解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

低酸素によるトロホブラストの増殖能亢進および分化・浸潤能消失のメカニズム解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Sirtuin 1 is a potential therapeutic candidate gene for fetal growth restriction via insulin-like 42023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] BMAL1 positively correlates with genes regulating steroidogenesis in human luteinized granulosa cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Long-Term Outcome of Children Conceived Through Assisted Reproductive Technology2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Circadian Clock, Nutritional Signals and Reproduction: A Close Relationship2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] WAPL induces cervical intraepithelial neoplasia modulated with estrogen signaling without HPV E6/E7. Oncogene.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Profiling analysis of circulating microRNA expression in cervical cancer2016

Nishi Hirotaka 西洋孝

NISHI Hirotaka 西洋孝

西洋孝ニシヒロタカ

[Presentation] 婦人科癌における腫瘍マーカーとしての血清中マイクロRNA - 1滴の血液による診断 -2018