Okamoto Akimitsu 岡本晃充

… Alternative Names

OKAMOTO Akimitsu 岡本晃充

岡本晃光オカモトアキミツ

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Researcher Number	60314233
Other IDs	https://orcid.org/0000-0002-7418-6237
Affiliation (Current)	2025: 東京大学, 大学院工学系研究科(工学部), 教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 東京大学, 大学院工学系研究科(工学部), 教授 2014 – 2023: 東京大学, 先端科学技術研究センター, 教授 2011: The Institute of Physical and Chemical Research, 研究員 2009 – 2010: The Institute of Physical and Chemical Research, 岡本独立主幹研究ユニット, ユニットリーダー(独立主幹研究員) 2008: The Institute of Physical and Chemical Research, 岡本独立主幹研究ユニット, 独立主幹研究員 … More 2007: The Institute of Physical and Chemical Research, 岡本独立主幹研究ユニット, 独立主幹研究員 2006: 独立行政法人理化学研究所, 岡本独立主幹研究ユニット, 独立主幹研究員 2000 – 2005: 京都大学, 工学研究科, 助手 2002: 京都大学, 工学研究科, 助教授 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Chemistry related to living body / Medium-sized Section 37:Biomolecular chemistry and related fields / Bio-related chemistry / Science and Engineering / Bioorganic chemistry / Transformative Research Areas, Section (II) / Chemistry related to living body / Complex systems / Transition State Control … More Except Principal Investigator … More Basic Section 57060:Surgical dentistry-related / Basic Section 27040:Biofunction and bioprocess engineering-related / Basic Section 38060:Applied molecular and cellular biology-related / Complex systems / Applied molecular and cellular biology / Bioorganic chemistry / Bio-related chemistry / Fusional basic brain science / Medical systems Less
Keywords	Principal Investigator 核酸 / 蛍光 / 化学合成 / オリゴヌクレオチド / 修飾核酸塩基 / 一塩基多型 / ヌクレオシド / メチルシトシン / エピジェネティクス / DNA … More / ゲノム機能 / ペプチド / ヒストン / 遺伝子解析 / ペプチド核酸 / マイクロRNA / ハイブリダイゼーション / 集合体 / ヌクレオソーム / リボース / RNA / 自己組織化膜 / 相分離 / クロマチン / タンパク質化学合成 / 蛍光標識 / タンパク質合成 / ユビキチン / 金属錯体 / ヒドロキシアパタイト / 有機化学 / 触媒 / リン酸 / イメージング / 色素 / 個別化医療 / がん / 電極 / ソラレン / 免疫 / 核酸集合体 / 化学反応 / プロテオミクス / メチル化酵素 / メチルアデニン / 化学修飾 / 転写因子 / 染色体 / ライゲーション / 1細胞イメージング / 合成化学 / 遺伝子制御 / ルテニウム / パラジウム / 安定同位体 / 酵素 / 立体科学 / 生命起源 / プロトヌクレオシド / バイオテクノロジー / ゲノム / 癌 / ＲＮＡ修飾 / ＤＮＡメチル化 / RNA修飾 / DNAメチル化 / ペプチド合成 / 金属反応 / 脱メチル化 / メチル化 / ADP / 固相合成 / ポリADP-リボース / 生体分子 / 立体化学 / ヒュースゲン環化 / 遷移状態 / 発酵 / バクテリア / 核酸構造 / アプタマー / 炭素-炭素三重結合 / 刺激応答性 / 細胞イメージング / 炭素－炭素三重結合 / ラマン分光 / 脱ケージング / 光反応 / 蛍光色素 / 蛍光イメージング / 励起子相互作用 / エピゲノム解析 / 同時多項目解析 / シトシンメチル化 / 人工核酸 / オスミウム / 金属酸化 / 電気化学測定 / DNAチップ / 遠隔ホール移動 / オリゴヌクレチド / デアザプリン / DNA四重鎖 … More Except Principal Investigator イムノトキシン / 抗体-薬物複合体 / オーファンドラッグ / 光線力学療法 / 口腔がん / 細胞分泌物 / セルソーティング / 1細胞解析 / 細胞工学 / 抗体 / ケージドタンパク質 / ヒドロゲル / 1細胞アレイ / 分泌細胞 / 細胞ソーティング / 一細胞解析 / 酵母 / ヒストン / GTP / 出芽酵母 / １細胞解析 / クロマチン / エピジェネティクス / 口腔癌 / ADC / Robo1 / PCI / セツキシマブ / 抗体薬物複合体 / ステープルペプチド / シグナル伝達 / タンパク質化学合成 / 標的タンパク質分解誘導剤 / タンパク質分解 / 翻訳後修飾 / ケミカルバイオロジー / ユビキチン / RNAプロファイリング / プロセッシングボディー / バイオテクノロジー / ストレス / 脱キャップ酵素 / mRNA分解 / 環境調和型農林水産 / 気候変動 / 環境対応 / 生体機能利用 / 野外環境 / イネ / 翻訳抑制 / mRNa分解 / シロイヌナズナ / RNA顆粒 / P-ボディー / ストレス顆粒 / 高温ストレス / 環境応答 / mRNA制御 / 植物 / reversible DNA ligation / pyrimidine analogs / 5-iododeoxyuridine / 5-vinyluracil / 可逆的な核酸連結 / ピリミジン類縁体 / 5-ヨードデオキシウリジン / 5ビニルウラシル / 生体分子 / センサー / 細胞膜 / 記憶 / プローブテクノロジー / イメージング技術 / in vivo / RNA ダイナミズム / 小脳 / 転写 / 空間分布 / RNA / イメージング / multiplex / 目視判定 / 新規蛍光物質 / 等温増幅 / 遺伝子増幅 / マルチプレックス / 増幅検出の可視化 / エキシトンプライマー / Virus Detection / Cancer / Visualization of amplified product / Two-color reaction / Mutation detection / SNP genotyping / Smart Amplification Process / EGFR / Warfarin / End Product Visualization / Multiplex reaction / Cancer Mutation Detection / SNPタイピング / Exciton Primer / SmartAmp法 Less

Epigenomic Chemical Transformations Caused by Nucleic Acid Molecular ReprogrammingPrincipal Investigator
- Principal Investigator
  
  岡本晃充
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  The University of Tokyo
Unprecedented and potent immunoregulation provided by protein capture with functionalized small synthetic nucleic acidsPrincipal Investigator
- Principal Investigator
  
  岡本晃充
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  The University of Tokyo
Analysis of the mechanism by which nucleic acid assemblies exhibit anticancer activityPrincipal Investigator
- Principal Investigator
  
  岡本晃充
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  The University of Tokyo
Studies on the development of antibody-drug conjugate orphan drugs based on photodynamic therapy targeting oral cancer.
- Principal Investigator
  
  安部貴大
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Kanagawa Dental College
特定のヘテロクロマチン領域を認識し遺伝子発現を制御するメカニズムの解明
- Principal Investigator
  
  沖昌也
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38060:Applied molecular and cellular biology-related
- Research Institution
  University of Fukui
Exploration of the modification of genomic higher-order structures in the cell nucleus by aggregation of chemically synthesized short nucleic acidsPrincipal Investigator
- Principal Investigator
  
  Okamoto Akimitsu
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  The University of Tokyo
Development of secretory cell sorting system using secretion-responsive single-cell array
- Principal Investigator
  
  Yamaguchi Satoshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  Osaka University
  The University of Tokyo
Developing next-generation PCI-based fluorescent-labeled antibody-drug conjugates for oral cancer therapy
- Principal Investigator
  
  Abe Takahiro
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Kanagawa Dental College
Synthesis and function analysis of mini-chromosome modelPrincipal Investigator
- Principal Investigator
  
  Okamoto Akimitsu
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  The University of Tokyo
Chemical synthesis of ubiquitin codesPrincipal Investigator
- Principal Investigator
  
  Okamoto Akimitsu
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
Single cell mapping of epigenetic modifications through super-nucleosome constructionPrincipal Investigator
- Principal Investigator
  
  Okamoto Akimitsu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  The University of Tokyo
New frontier for ubiquitin biology driven by chemo-technologies
- Principal Investigator
  
  SAEKI Yasushi
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Nucleoside synthesis: Apatite phosphate catalytic reaction from glycolaldehydePrincipal Investigator
- Principal Investigator
  
  岡本晃充
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Development of nucleic acid enzymes for new nucleic acid medicines based on the transition state in molecular degradationPrincipal Investigator
- Principal Investigator
  
  Okamoto Akimitsu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Transition State Control
- Research Institution
  The University of Tokyo
ヌクレオシド合成：グリコールアルデヒドを起点とするアパタイトリン酸触媒反応Principal Investigator
- Principal Investigator
  
  岡本晃充
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Fine chemical synthesis of poly(ADP-ribose) for disease studiesPrincipal Investigator
- Principal Investigator
  
  Okamoto Akimitsu
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Bio-related chemistry
- Research Institution
  The University of Tokyo
Development of highly sensitive chemical detection of the nucleic acid methylations strongly affecting lifestyle diseasesPrincipal Investigator
- Principal Investigator
  
  Okamoto Akimitsu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Bio-related chemistry
- Research Institution
  The University of Tokyo
Analysis of mRNA fates with exclusive function mediated by RNA granules
- Principal Investigator
  
  Watanabe Yuichiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  The University of Tokyo
Molecular Chemistry on Cell Membrane Using Functional Nucleic Acid
- Principal Investigator
  
  SANDO SHINSUKE
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bio-related chemistry
- Research Institution
  The University of Tokyo
Development of molecular probes for Raman bioimagingPrincipal Investigator
- Principal Investigator
  
  OKAMOTO Akimitsu
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Bio-related chemistry
- Research Institution
  The University of Tokyo
核酸のエピジェネティック修飾の化学的検出Principal Investigator
- Principal Investigator
  
  岡本晃充
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Chemistry related to living body
- Research Institution
  The University of Tokyo
4D Gene Analysis in Functional Neuronal Circuits
- Principal Investigator
  
  WANG Dan Ohtan
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Fusional basic brain science
- Research Institution
  Kyoto University
化学的核酸設計に立脚した高機能RNA検出系のデザインPrincipal Investigator
- Principal Investigator
  
  岡本晃充
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  The Institute of Physical and Chemical Research
第6天然核酸塩基ヒドロキシメチルシトシンの高効率化学標識Principal Investigator
- Principal Investigator
  
  岡本晃充
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemistry related to living body
- Research Institution
  The Institute of Physical and Chemical Research
Artificial nucleic acids for molecular diagnosis of cancer individualityPrincipal Investigator
- Principal Investigator
  
  OKAMOTO Akimitsu
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
Development of high sensitive and high S/N ratio multicolored SNP detection technology toward each locus.
- Principal Investigator
  
  LEZHAVA Alexander
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical systems
- Research Institution
  The Institute of Physical and Chemical Research
Exciton-controlled imaging for effective spatiotemporal analysis of nucleic acid functionsPrincipal Investigator
- Principal Investigator
  
  OKAMOTO Akimitsu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  The Institute of Physical and Chemical Research
生体機能観察のための新規光開始型色素の設計Principal Investigator
- Principal Investigator
  
  岡本晃充
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemistry related to living body
- Research Institution
  The Institute of Physical and Chemical Research
がんの個性の分子診断のための人工機能性核酸Principal Investigator
- Principal Investigator
  
  岡本晃充
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
がんの個性の分子診断のための人工機能性核酸Principal Investigator
- Principal Investigator
  
  岡本晃充
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
個別化医療を目指した簡便遺伝子解析法の開発Principal Investigator
- Principal Investigator
  
  岡本晃充
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
新規光機能性人工核酸をベースにした効率的ゲノム解析法Principal Investigator
- Principal Investigator
  
  岡本晃充
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Chemistry related to living body
- Research Institution
  The Institute of Physical and Chemical Research
  Kyoto University
ゲノム機能の調節を指向した機能性ペプチド核酸の開発Principal Investigator
- Principal Investigator
  
  岡本晃充
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
ゲノム機能の調節を指向した機能性ペプチド核酸の開発Principal Investigator
- Principal Investigator
  
  岡本晃充
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
機能性核酸を用いた遺伝子解析システムの開発Principal Investigator
- Principal Investigator
  
  岡本晃充
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
核酸自己組織化膜を利用したハイスループット可能なバイオセンサーの開発Principal Investigator
- Principal Investigator
  
  岡本晃充
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Chemistry related to living body
- Research Institution
  Kyoto University
ゲノム機能の調節を指向した機能性ペプチド核酸の開発Principal Investigator
- Principal Investigator
  
  岡本晃充
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
核酸自己組織化膜を利用したハイスループット可能なバイオセンサーの開発Principal Investigator
- Principal Investigator
  
  岡本晃充
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Kyoto University
ゲノム機能の調節を指向した機能性ペプチド核酸の開発Principal Investigator
- Principal Investigator
  
  岡本晃充
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Gene Manipulation using Laser
- Principal Investigator
  
  SAITO Isao
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  KYOTO UNIVERSITY
DNA四重鎖構造を利用した分子認識システムに関する研究Principal Investigator
- Principal Investigator
  
  岡本晃充
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Kyoto University

[Book] 実験医学増刊生命現象の動的理解を目指すライブイメージング「第3章-5生細胞内mRNAの検出」2008
- Author(s)
  岡本晃充
- Total Pages
  7
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-20655039
[Book] 実験医学増刊生命現象の動的理解を目指すライブイメージング「第3章-5生細胞内mRNAの検出」2008
- Author(s)
  岡本晃充
- Total Pages
  7
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-20350083
[Book] 実験医学増刊生命現象の動的理解を目指すライブイメージング「第3章-5 生細胞内 mRNA の検出」2008
- Author(s)
  岡本晃充
- Total Pages
  7
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-20014030
[Journal Article] An osteoinductive surface by adhesive bone morphogenetic protein-2 prepared using the bioorthogonal approach for tight binding of titanium with bone2024
- Author(s)
  Ren, X.; Tsuji, H.; Uchino, T.; Kono, I.; Isoshima, T.; Okamoto, A.; Nagaoka, N.; Ozaki, T.; Matsukawa, A.; Miyatake, H.; Ito, Y.
- Journal Title
  
  J. Mater. Chem. B
  
  Volume: 12 Issue: 12 Pages: 3006-3014
- DOI
  10.1039/d3tb02838k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K17969, KAKENHI-PROJECT-23H00317
[Journal Article] Odorant-sensing cell micropatterns for odor discrimination2024
- Author(s)
  Yamahira, S.; Mitsuno, H.; Yamaoka, M.; Nagamune, T.; Okamoto, A.; Kanzaki, R.; Yamaguchi, S.
- Journal Title
  
  Biosens. Bioelectron.:X
  
  Volume: 18 Pages: 100473-100473
- DOI
  10.1016/j.biosx.2024.100473
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K17969, KAKENHI-PROJECT-23H00317
[Journal Article] Cellular Penetration and Intracellular Dynamics of Perfluorocarbon-Conjugated DNA/RNA as a Potential Means of Conditional Nucleic Acid Delivery2023
- Author(s)
  Takatsu, M.; Morihiro, K.; Watanabe, H.; Yuki, M.; Hattori, T.; Noi, K.; Aikawa, K.; Noguchi, K.; Yohda, M.; Okazoe, T.; Okamoto, A.
- Journal Title
  
  ACS Chem. Biol.
  
  Volume: 18 Issue: 12 Pages: 2590-2598
- DOI
  10.1021/acschembio.3c00612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K17969, KAKENHI-PROJECT-23K04717, KAKENHI-PROJECT-23H00317
[Journal Article] Oncolytic Hairpin DNA Pair: Selective Cytotoxic Inducer through MicroRNA-Triggered DNA Self-Assembly2023
- Author(s)
  Morihiro, K.; Osumi, H.; Morita, S.; Hattori, T.; Baba, M.; Harada, N.; Ohashi, R.; Okamoto, A.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 145 Issue: 1 Pages: 135-142
- DOI
  10.1021/jacs.2c08974
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K19040, KAKENHI-PLANNED-18H05504
[Journal Article] Nucleic Acid-to-Small Molecule Converter through Amplified Hairpin DNA Circuits2023
- Author(s)
  Morihiro, K.; Tomida, Y.; Fukui, D.; Hasegawa, M.; Okamoto, A.
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 62 Issue: 44
- DOI
  10.1002/anie.202306587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K17969, KAKENHI-PROJECT-23H00317
[Journal Article] RNA Oncological Therapeutics: Intracellular Hairpin RNA Assembly Enables MicroRNA-Triggered Anticancer Functionality2023
- Author(s)
  Morihiro, K.; Morita, S.; Harada, N.; Baba, M.; Yum, J.; Naito, M.; Miyata, K.; Nagae, G.; Okamoto, A.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 146 Issue: 2 Pages: 1346-1355
- DOI
  10.1021/jacs.3c09524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K17969, KAKENHI-PROJECT-23H00317, KAKENHI-PROJECT-23K21431
[Journal Article] Cytosolic protein delivery using ultrasound-guided vaporization of perfluorocarbon nano-droplets2023
- Author(s)
  Yamaguchi, S.; Kisaka, M.; Higashi, K.; Ishijima, A.; Azuma, T.; Nakagawa, K.; Shibasaki, Y.; Sakuma, I.; Okamoto, A.
- Journal Title
  
  Biotechnol. J.
  
  Volume: 18 Issue: 7
- DOI
  10.1002/biot.202300018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K17969, KAKENHI-PROJECT-23H00317
[Journal Article] One-Pot, Photocontrolled Enzymatic Assembly of the Structure-Defined Heterotypic Polyubiquitin Chain2023
- Author(s)
  Furuhata, T.; Racheal, P. A. D.; Murayama, I.; Toyoda, U.; Okamoto, A.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 145 Pages: 11690-11700
- DOI
  10.1021/jacs.3c01912
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K17969, KAKENHI-PROJECT-22K14778, KAKENHI-WRAPUP-23H05424, KAKENHI-PUBLICLY-23H04253, KAKENHI-PROJECT-23H00317
[Journal Article] Thiocholine-Mediated One-Pot Peptide Ligation and Desulfurization2023
- Author(s)
  Suzuki, S.; Nakajima, Y.; Kamo, N.; Osakabe A.; Okamoto, A.; Hayashi, G.; Murakami, H.
- Journal Title
  
  Molecules
  
  Volume: 28 Issue: 9 Pages: 3655-3655
- DOI
  10.3390/molecules28093655
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K17969, KAKENHI-PROJECT-23H00317
[Journal Article] Interstrand Crosslinking Oligonucleotides Elucidate the Effect of Metal Ions on the Methylation Status of Repetitive DNA Elements2023
- Author(s)
  Liu, S.; Morihiro, K.; Takeuchi, F.; Li, Y.; Okamoto, A.
- Journal Title
  
  Front. Chem.
  
  Volume: 11 Pages: 1122474-1122474
- DOI
  10.3389/fchem.2023.1122474
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19040, KAKENHI-PLANNED-18H05504
[Journal Article] Photoactivatable Materials for Versatile Single-Cell Patterning Based on the Photocaging of Cell-Anchoring Moieties through Lipid Self-Assembly2022
- Author(s)
  Yamahira Shinya、Misawa Ryuji、Kosaka Takahiro、Tan Mondong、Izuta Shin、Yamashita Hayato、Heike Yuji、Okamoto Akimitsu、Nagamune Teruyuki、Yamaguchi Satoshi
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 144 Issue: 29 Pages: 13154-13162
- DOI
  10.1021/jacs.2c02949
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K04898, KAKENHI-PROJECT-22K18945, KAKENHI-PROJECT-20H03223, KAKENHI-PROJECT-21K19040, KAKENHI-PLANNED-18H05504
[Journal Article] Bioorthogonal Photoreactive Surfaces for Single-Cell Analysis of Intercellular Communications2022
- Author(s)
  Kosaka Takahiro、Yamaguchi Satoshi、Izuta Shin、Yamahira Shinya、Shibasaki Yoshikazu、Tateno Hiroaki、Okamoto Akimitsu
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 144 Issue: 39 Pages: 17980-17988
- DOI
  10.1021/jacs.2c07321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20J22920, KAKENHI-PROJECT-21K19040, KAKENHI-PLANNED-18H05504
[Journal Article] cIAP1-based degraders induce degradation via branched ubiquitin architectures2022
- Author(s)
  Akizuki Yoshino、Morita Mai、Mori Yuki、Kaiho-Soma Ai、Dixit Shivani、Endo Akinori、Shimogawa Marie、Hayashi Gosuke、Naito Mikihiko、Okamoto Akimitsu、Tanaka Keiji、Saeki Yasushi、Ohtake Fumiaki
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 19 Issue: 3 Pages: 311-322
- DOI
  10.1038/s41589-022-01178-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22H00419, KAKENHI-PROJECT-20K06568, KAKENHI-PROJECT-21K19040, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PLANNED-18H05502, KAKENHI-PLANNED-18H05504, KAKENHI-PROJECT-21H02777
[Journal Article] Glutamine deficiency in solid tumor cells confers resistance to ribosomal RNA synthesis inhibitors2022
- Author(s)
  Melvin Pan、Christiane Zorbas、Maki Sugaya、Kensuke Ishiguro、Miki Kato、Miyuki Nishida、Hai-Feng Zhang、Marco M. Candeias、Akimitsu Okamoto、Takamasa Ishikawa、Tomoyoshi Soga、Hiroyuki Aburatani、Juro Sakai、Yoshihiro Matsumura、Tsutomu Suzuki、Christopher G. Proud、Denis L. J. Lafontaine、Tsuyoshi Osawa
- Journal Title
  
  Nature Communications
  
  Volume: 13(1) Issue: 1 Pages: 3706-3706
- DOI
  10.1038/s41467-022-31418-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-19H01031, KAKENHI-PROJECT-19H03496, KAKENHI-PROJECT-21K19040, KAKENHI-PROJECT-21K19399, KAKENHI-PROJECT-21H04826, KAKENHI-PLANNED-18H05504, KAKENHI-PROJECT-18H05272
[Journal Article] Repetitive Thiazolidine Deprotection Using a Thioester-Compatible Aldehyde Scavenger for One-Pot Multiple Peptide Ligation.2022
- Author(s)
  Nakatsu, K.; Okamoto, A.; Hayashi, G.; Murakami, H.
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 61 Issue: 39
- DOI
  10.1002/anie.202206240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22KJ1585, KAKENHI-PROJECT-21K19040, KAKENHI-PLANNED-18H05504
[Journal Article] Intracellular Protein Photoactivation Using Sterically Bulky Caging2022
- Author(s)
  Yamaguchi, S.; Yamamoto, K.; Yamamoto, R.; Takamori, S.; Ishiwatari, A.; Minamihata, K.; Nagamune, T.; Okamoto, A.
- Journal Title
  
  ChemBioChem
  
  Volume: 23 Issue: 22
- DOI
  10.1002/cbic.202200476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K19040, KAKENHI-PLANNED-18H05504
[Journal Article] Chemoenzymatic labeling to visualize intercellular contacts using lipidated sortase A2022
- Author(s)
  Yamaguchi, S.; Ikeda, R.; Umeda, Y.; Kosaka, T.; Yamahira, S.; Okamoto, A.
- Journal Title
  
  ChemBioChem
  
  Volume: 23 Issue: 21
- DOI
  10.1002/cbic.202200474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K19040, KAKENHI-PLANNED-18H05504
[Journal Article] Sterically Bulky Caging of Transferrin for Photoactivatable Intracellular Delivery2021
- Author(s)
  Yamaguchi, S.; Takamori, S.; Yamamoto, K.; Ishiwatari, A.; Minamihata, K.; Yamada, E.; Okamoto, A.; Nagamune, T.
- Journal Title
  
  Bioconjugate Chem.
  
  Volume: 32 Issue: 8 Pages: 1535-1540
- DOI
  10.1021/acs.bioconjchem.1c00159
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05504, KAKENHI-PROJECT-21K19040, KAKENHI-PROJECT-19K22079
[Journal Article] Base-Resolution Analysis of 5-Hydroxymethylcytidine by Selective Oxidation and Reverse Transcription Arrest2021
- Author(s)
  Koyama, K.; Hayashi, G.; Ueda, H.; Ota, S.; Nagae, G.; Aburatani, H.; Okamoto, A.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 19 Issue: 29 Pages: 6478-6486
- DOI
  10.1039/d1ob00995h
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05504, KAKENHI-PUBLICLY-20H04704, KAKENHI-PROJECT-21K19040, KAKENHI-PROJECT-23K21431, KAKENHI-PUBLICLY-21H00278
[Journal Article] Changes of C≡C Triple Bond Vibration that Disclosed Non-Canonical Cytosine Protonation in i-Motif-Forming Oligodeoxynucleotides2021
- Author(s)
  Itaya, R.; Idei, W.; Nakamura, T.; Nishihara, T.; Kurihara, R.; Okamoto, A.; Tanabe, K.
- Journal Title
  
  ACS Omega
  
  Volume: 6 Issue: 47 Pages: 31595-31604
- DOI
  10.1021/acsomega.1c04074
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05504, KAKENHI-PROJECT-21K19040, KAKENHI-PROJECT-20H02863
[Journal Article] Silyl-Protected Propargyl Glycine for Multiple Labeling of Peptides by Chemoselective Silyl-Deprotection2021
- Author(s)
  Kamo, N.; Hayashi, G.; Okamoto, A.
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 73 Pages: 153093-153093
- DOI
  10.1016/j.tetlet.2021.153093
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05504, KAKENHI-PUBLICLY-20H04704, KAKENHI-PROJECT-21K19040, KAKENHI-PUBLICLY-21H00278
[Journal Article] anti-syn Unnatural Base Pair Enables Alphabet-Expanded DNA Self-Assembly2021
- Author(s)
  Morihiro, K.; Moriyama, Y.; Nemoto, Y.; Osumi, H.; Okamoto, A.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 143 Issue: 35 Pages: 14207-14217
- DOI
  10.1021/jacs.1c05393
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05504, KAKENHI-PROJECT-21K19040
[Journal Article] Floxuridine Oligomers Activated under Hypoxic Environment2021
- Author(s)
  Morihiro, K.; Ishinabe, T.; Takatsu, M.; Osumi, H.; Osawa, T.; Okamoto, A.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 143 Issue: 9 Pages: 3340-3347
- DOI
  10.1021/jacs.0c10732
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05504, KAKENHI-PUBLICLY-20H04698, KAKENHI-PROJECT-18H03931, KAKENHI-PROJECT-19K22245, KAKENHI-PROJECT-19K15408, KAKENHI-PUBLICLY-20H04834, KAKENHI-PROJECT-19H03496, KAKENHI-PROJECT-21K19399
[Journal Article] Organoruthenium-Catalyzed Chemical Protein Synthesis to Elucidate the Functions of Epigenetic Modifications on Heterochromatin Factors2021
- Author(s)
  Kamo, N.; Kujirai, T.; Kurumizaka, H.; Murakami, H.; Hayashi, G.; Okamoto, A.
- Journal Title
  
  Chem. Sci.
  
  Volume: 12 Issue: 16 Pages: 5926-5937
- DOI
  10.1039/d1sc00731a
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05504, KAKENHI-PLANNED-18H05534, KAKENHI-PUBLICLY-20H04704, KAKENHI-PROJECT-18H03931, KAKENHI-PROJECT-19J13608, KAKENHI-PROJECT-19K22245, KAKENHI-PUBLICLY-19H05287, KAKENHI-PROJECT-18K05313
[Journal Article] Light-inducible control of cellular proliferation and differentiation by a Hedgehog signaling inhibitor2021
- Author(s)
  Misawa Ryuji、Minami Tsuyoshi、Okamoto Akimitsu、Ikeuchi Yoshiho
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 38 Pages: 116144-116144
- DOI
  10.1016/j.bmc.2021.116144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20643, KAKENHI-PLANNED-18H05504, KAKENHI-PLANNED-20H05786, KAKENHI-PROJECT-18H03931, KAKENHI-PROJECT-19K22245
[Journal Article] Poly(A)+ Sensing of Hybridization-Sensitive Fluorescent Oligonucleotide Probe Characterized by Fluorescence Correlation Methods2021
- Author(s)
  Paulson, B.; Shin, Y.; Okamoto, A.; Oh, Y.-M.; Kim, J. K.; Pack, C.-G.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 22 Issue: 12 Pages: 6433-6433
- DOI
  10.3390/ijms22126433
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05504, KAKENHI-PROJECT-21K19040
[Journal Article] Monitoring intracellular metal ion complexation with acetylene-tagged ligand by Raman spectroscopy2020
- Author(s)
  Takemura, S.; Watanabe, H.; Nishihara, T.; Okamoto, A.; Tanabe, K.
- Journal Title
  
  RSC Adv.
  
  Volume: 10 Issue: 59 Pages: 36119-36123
- DOI
  10.1039/d0ra06329k
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05504, KAKENHI-PROJECT-18H03931, KAKENHI-PROJECT-20H02863, KAKENHI-PROJECT-19K22245
[Journal Article] A highly constrained nucleic acid analog based on α-L-threosamine2020
- Author(s)
  Morihiro, K.; Okamoto, A.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids
  
  Volume: 39 Issue: 1-3 Pages: 270-279
- DOI
  10.1080/15257770.2019.1666278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22245, KAKENHI-PLANNED-18H05504, KAKENHI-PROJECT-18H03931
[Journal Article] A light-inducible Hedgehog signaling activator modulates proliferation and differentiation of neural cells.2020
- Author(s)
  Ryuji Misawa, Tsuyoshi Minami, Akimitsu Okamoto, Yoshiho Ikeuchi.
- Journal Title
  
  ACS Chemical Biology
  
  Volume: - Issue: 6 Pages: 1595-1603
- DOI
  10.1021/acschembio.0c00195
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19J14421, KAKENHI-PLANNED-18H05504, KAKENHI-PROJECT-18H03931, KAKENHI-PROJECT-19K22245, KAKENHI-PROJECT-18K19903
[Journal Article] Live Cell Sensing of Telomerase Activity Using Hybridization-Sensitive Fluorescent Oligonucleotide Probes2020
- Author(s)
  Chen, J.; Morihiro, K.; Fukui, D.; Guo, L.; Okamoto, A.
- Journal Title
  
  ChemBioChem
  
  Volume: 21 Issue: 7 Pages: 1022-1027
- DOI
  10.1002/cbic.201900555
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22245, KAKENHI-PLANNED-18H05504, KAKENHI-PROJECT-18H03931
[Journal Article] Fmoc-Compatible and C-terminal-Sequence-Independent Peptide Alkyl Thioester Formation Using Cysteinylprolyl Imide2020
- Author(s)
  Nakatsu, K.; Yanase, M.; Hayashi, G.; Okamoto, A.
- Journal Title
  
  Org. Lett.
  
  Volume: 22 Issue: 12 Pages: 4670-4674
- DOI
  10.1021/acs.orglett.0c01450
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05504, KAKENHI-PUBLICLY-20H04704, KAKENHI-PROJECT-18H03931, KAKENHI-PROJECT-19K22245, KAKENHI-PUBLICLY-19H05287, KAKENHI-PROJECT-18K05313
[Journal Article] L-DNA-tagged fluorescence in situ hybridization for highly sensitive imaging of RNAs in single cells2020
- Author(s)
  Ogata, M.; Hayashi, G.; Ichiu, A.; Okamoto, A.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 18 Issue: 40 Pages: 8084-8088
- DOI
  10.1039/d0ob01635g
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05504, KAKENHI-PUBLICLY-20H04704, KAKENHI-PROJECT-18H03931, KAKENHI-PROJECT-19K22245, KAKENHI-PUBLICLY-19H05287, KAKENHI-PROJECT-18K05313
[Journal Article] Single cell array enclosed with a photodegradable hydrogel in microwells for image-based cell classification and selective photorelease of cells2020
- Author(s)
  Yamaguchi, S.; Takagi, R.; Hosogane, T.; Ohashi, Y.; Sakai, Y.; Sakakihara, S.; Iino, R.; Tabata, K.; Noji, H.; Okamoto, A.
- Journal Title
  
  ACS Appl. Bio Mater.
  
  Volume: 3 Issue: 9 Pages: 5887-5895
- DOI
  10.1021/acsabm.0c00583
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05504, KAKENHI-PROJECT-18H03931, KAKENHI-PROJECT-19K22245
[Journal Article] Toolbox for chemically synthesized histone proteins2020
- Author(s)
  Nakatsu, K.; Hayashi, G.; Okamoto, A.
- Journal Title
  
  Curr. Opin. Chem. Biol.
  
  Volume: 58 Pages: 10-19
- DOI
  10.1016/j.cbpa.2020.04.016
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05504, KAKENHI-PUBLICLY-20H04704, KAKENHI-PROJECT-18H03931, KAKENHI-PROJECT-19K22245, KAKENHI-PUBLICLY-19H05287, KAKENHI-PROJECT-18K05313
[Journal Article] Chemical Synthesis of Cys-Containing Protein via Chemoselective Deprotection with Different Palladium Complexes2019
- Author(s)
  Kamo, N.; Hayashi, G.; Okamoto, A.
- Journal Title
  
  Org. Lett.
  
  Volume: 21 Issue: 20 Pages: 8378-8382
- DOI
  10.1021/acs.orglett.9b03152
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22245, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05504, KAKENHI-PUBLICLY-19H05287, KAKENHI-PROJECT-18H03931, KAKENHI-PROJECT-19J13608
[Journal Article] Supramolecular Polymeric Hydrogels for Ultrasound-guided Protein Release2019
- Author(s)
  Yamaguchi, S; Higashi, K.; Azuma, T.; Okamoto, A.
- Journal Title
  
  Biotechnol. J.
  
  Volume: 14 Issue: 5 Pages: 1800530-1800530
- DOI
  10.1002/biot.201800530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22245, KAKENHI-PLANNED-18H05504, KAKENHI-PROJECT-18H03931
[Journal Article] Photo-responsive materials with strong cell trapping ability for light-guided manipulation of nonadherent cells2019
- Author(s)
  Jarzebska, N. A.; Yamaguchi, S.; Izuta, S.; Kosaka, T.; Yamahira, S.; Nagamune, T.; Okamoto, A.
- Journal Title
  
  Biomater. Sci.
  
  Volume: 7 Issue: 11 Pages: 4514-4518
- DOI
  10.1039/c9bm01200a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22245, KAKENHI-PROJECT-19K15366, KAKENHI-PLANNED-18H05504, KAKENHI-PROJECT-18H03931, KAKENHI-PROJECT-19K22079
[Journal Article] Reversible and Photoresponsive Immobilization of Nonadherent Cells by Spiropyran-Conjugated PEG-Lipids2019
- Author(s)
  Izuta, S.; Yamaguchi, S.; Kosaka, T.; Okamoto, A.
- Journal Title
  
  ACS Appl. Bio Mater.
  
  Volume: 2 Issue: 1 Pages: 33-38
- DOI
  10.1021/acsabm.8b00656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22245, KAKENHI-PLANNED-18H05504, KAKENHI-PROJECT-18H03931
[Journal Article] Simultaneous and Traceless Ligation of Peptide Fragments on DNA Scaffold.2019
- Author(s)
  Hayashi G, Yanase M, Nakatsuka Y, Okamoto A.
- Journal Title
  
  Biomaclomolecules
  
  Volume: 20 Issue: 3 Pages: 1246-1253
- DOI
  10.1021/acs.biomac.8b01655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05313, KAKENHI-PROJECT-19K22245, KAKENHI-PLANNED-18H05504, KAKENHI-PROJECT-18H03931
[Journal Article] Cysteinylprolyl imide (CPI) peptide: a highly reactive and easily accessible crypto-thioester for chemical protein synthesis2019
- Author(s)
  Yanase Masafumi、Nakatsu Koki、Cardos Charlane Joy、Konda Yoshiki、Hayashi Gosuke、Okamoto Akimitsu
- Journal Title
  
  Chemical Science
  
  Volume: 10 Issue: 23 Pages: 5967-5975
- DOI
  10.1039/c9sc00646j
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05313, KAKENHI-PROJECT-19K22245, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05504, KAKENHI-PUBLICLY-19H05287, KAKENHI-PROJECT-18H03931
[Journal Article] Efficient Ketose Production by Hydroxyapatite Catalyst in a Continuous Flow Module2019
- Author(s)
  Usami, K.; Xiao, K.; Okamoto, A.
- Journal Title
  
  ACS Sustainable Chem. Eng.
  
  Volume: 7 Issue: 3 Pages: 3372-3377
- DOI
  10.1021/acssuschemeng.8b05574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22245, KAKENHI-PLANNED-18H05504, KAKENHI-PROJECT-18H03931
[Journal Article] Efficient peptide ligation between allyl-protected Asp and Cys followed by palladium-mediated deprotection2018
- Author(s)
  Kamo Naoki、Hayashi Gosuke、Okamoto Akimitsu
- Journal Title
  
  Chemical Communications
  
  Volume: 54 Issue: 34 Pages: 4337-4340
- DOI
  10.1039/c8cc01965g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02190, KAKENHI-PROJECT-18H03931
[Journal Article] Chemistry‐Driven Epigenetic Investigation of Histone and DNA Modifications2018
- Author(s)
  Sueoka Takuma、Koyama Kenta、Hayashi Gosuke、Okamoto Akimitsu
- Journal Title
  
  The Chemical Record
  
  Volume: 18 Issue: 12 Pages: 1727-1744
- DOI
  10.1002/tcr.201800040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03931, KAKENHI-PROJECT-17J09621
[Journal Article] Photophysical properties of fluorescent imaging biological probes of nucleic acids: SAC-CI and TD-DFT Study2018
- Author(s)
  Shiraogawa Takafumi、Candel Gaelle、Fukuda Ryoichi、Ciofini Ilaria、Adamo Carlo、Okamoto Akimitsu、Ehara Masahiro
- Journal Title
  
  Journal of Computational Chemistry
  
  Volume: 40 Issue: 1 Pages: 127-134
- DOI
  10.1002/jcc.25553
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K05749, KAKENHI-PROJECT-17KT0097, KAKENHI-PLANNED-16H06511, KAKENHI-PROJECT-16H04104, KAKENHI-PROJECT-19K22245, KAKENHI-PLANNED-18H05504, KAKENHI-PROJECT-18H03931
[Journal Article] Triple Function of 4-Mercaptophenylacetic Acid Promotes One-Pot Multiple Peptide Ligation2018
- Author(s)
  Kamo Naoki、Hayashi Gosuke、Okamoto Akimitsu
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 57 Issue: 50 Pages: 16533-16537
- DOI
  10.1002/anie.201809765
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03931
[Journal Article] Chemically-activatable alkyne-tagged probe for imaging microdomains in lipid bilayer membranes2017
- Author(s)
  Yamaguchi, S.; Matsushita, T.; Izuta, S.; Katada, S.; Ura, M.; Ikeda, T. ;Hayashi, G.; Suzuki, Y.; Kobayashi, Y.; Tokunaga, K.; Ozeki, Y.; Okamoto, A.
- Journal Title
  
  Sci. Rep.
  
  Volume: 7 Issue: 1 Pages: 41007-41007
- DOI
  10.1038/srep41007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02190, KAKENHI-PROJECT-15J09208
[Journal Article] DNA-friendly Cu(ii)/TEMPO-catalyzed 5-hydroxymethylcytosine-specific oxidation2017
- Author(s)
  Matsushita T, Moriyama Y, Nagae G, Aburatani H, Okamoto A
- Journal Title
  
  Chemical Communications
  
  Volume: 53 Issue: 42 Pages: 5756-5759
- DOI
  10.1039/c7cc02814h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08987, KAKENHI-PROJECT-15H02190
[Journal Article] Chemical synthesis of dual labeled proteins via differently protected alkynes enables intramolecular FRET analysis2017
- Author(s)
  Hayashi Gosuke、Kamo Naoki、Okamoto Akimitsu
- Journal Title
  
  Chemical Communications
  
  Volume: 53 Issue: 43 Pages: 5918-5921
- DOI
  10.1039/c7cc02612a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02190
[Journal Article] Hydroxyapatite: catalyst for a one-pot pentose formation2017
- Author(s)
  Usami K.、Okamoto A.
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 15 Issue: 42 Pages: 8888-8893
- DOI
  10.1039/c7ob02051a
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05227
[Journal Article] Fluorescence-switching RNA for detection of bacterial ribosomes2017
- Author(s)
  Guo Lihao、Okamoto Akimitsu
- Journal Title
  
  Chemical Communications
  
  Volume: 53 Issue: 68 Pages: 9406-9409
- DOI
  10.1039/c7cc04818a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15KT0057
[Journal Article] Regulation of the Stability of the Histone H2A?H2B Dimer by H2A Tyr57 Phosphorylation2017
- Author(s)
  Sueoka Takuma、Hayashi Gosuke、Okamoto Akimitsu
- Journal Title
  
  Biochemistry
  
  Volume: 56 Issue: 36 Pages: 4767-4772
- DOI
  10.1021/acs.biochem.7b00504
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02190, KAKENHI-PROJECT-15J08667
[Journal Article] Hybridization-sensitive Fluorescent Oligonucleotide Probe Conjugated with Cell-penetrating Peptides for Enhanced Cellular Uptake2017
- Author(s)
  Hayashi Gosuke、Tamai Makoto、Okamoto Akimitsu
- Journal Title
  
  Chemistry Letters
  
  Volume: 46 Issue: 12 Pages: 1803-1806
- DOI
  10.1246/cl.170813
- NAID
  130006243207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02190
[Journal Article] Base-Resolution Analysis of 5-Hydroxymethylcytosine by One-Pot Bisulfite-Free Chemical Conversion with Peroxotungstate.2016
- Author(s)
  Hayashi G, Koyama K, Shiota H, Kamio A, Umeda T, Nagae G, Aburatani H, Okamoto A.
- Journal Title
  
  J Am Chem Soc.
  
  Volume: 138 Issue: 43 Pages: 14178-14181
- DOI
  10.1021/jacs.6b06428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-15H02190
[Journal Article] Chemically Activatable Alkyne Tag for Low pH-Enhanced Molecular Labeling on Living Cells2016
- Author(s)
  Yamaguchi,S.; Ura, M.; Izuta, S.; Okamoto, A.
- Journal Title
  
  Bioconjugate Chem.
  
  Volume: 27 Issue: 9 Pages: 1976-1980
- DOI
  10.1021/acs.bioconjchem.6b00399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02190
[Journal Article] In vitro and in cell analysis of chemically synthesized histone H2A with multiple modifications2016
- Author(s)
  Gosuke Hayashi, Takuma Sueoka, Akimitsu Okamoto
- Journal Title
  
  Chemical Communications
  
  Volume: 52 Issue: 28 Pages: 4999-5002
- DOI
  10.1039/c5cc10555b
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15J08667, KAKENHI-PROJECT-15H02190
[Journal Article] Rapid nuclear import of short nucleic acids2016
- Author(s)
  Kitagawa, M.; Okamoto, A.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 26 Issue: 19 Pages: 4568-4570
- DOI
  10.1016/j.bmcl.2016.08.085
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H02190
[Journal Article] Diazirine Photocrosslinking Recruits Activated FTO Demethylase Complexes for Specific N6-methyladenosine Recognition2015
- Author(s)
  Jeong, H. S.; Hayashi, G.; Okamoto, A
- Journal Title
  
  ACS Chem. Biol.
  
  Volume: 10 Issue: 6 Pages: 1450-1455
- DOI
  10.1021/cb5010096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03342, KAKENHI-PROJECT-15H02190
[Journal Article] FTO-Dependent Demethylation of N6-Methyladenosine Regulates mRNA Splicing and Is Required for Adipogenesis2014
- Author(s)
  Yang, Y. G.; Zhao, X.; Yang, Y.; Sun, B. F.; Shi, Y.; Yang, X.; Xiao, W.; Hao, Y.; Ping, X.-L.; Chen, Y.; Wang, W.-J.; Jin, K.-X.; Wang, X.; Huang, C.; Fu, Y.; Ge, X.; Song, S.; Jeong, H. S.; Yanagisawa, H.; Niu, Y.; Jia, G.; Wu, W.; Tong, W.-M.; Okamoto, A.; He, C.; Danielsen, J. M.; Wang, X.
- Journal Title
  
  Cell Res.
  
  Volume: 24 Pages: 1403-1419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26620129
[Journal Article] DNA-Osmium Complexes: Recent Developments for Operative Chemical Analysis of DNA Epigenetic Modification2014
- Author(s)
  Okamoto, A.
- Journal Title
  
  ChemMedChem
  
  Volume: 9 Pages: 1958-1965
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26620129
[Journal Article] Whole-mount MeFISH : A novel technique for simultaneous visualization of specific DNA methylation and protein/RNA expression2014
- Author(s)
  Shiura, H. ; Okamoto, A. ; Sasaki, H. ; Abe, K.
- Journal Title
  
  PLoS ONE
  
  Volume: 9-4 Issue: 4 Pages: e95750-e95750
- DOI
  10.1371/journal.pone.0095750
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13F03342, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112010, KAKENHI-PUBLICLY-26112515, KAKENHI-PROJECT-26250025
[Journal Article] FTO-Dependent Demethylation of N6-Methyladenosine Regulates mRNA Splicing and Is Required for Adipogenesis2014
- Author(s)
  Yang, Y. G.; Zhao, X.; Yang, Y.; Sun, B. F.; Shi, Y.; Yang, X.; Xiao, W.; Hao, Y.; Ping, X.-L.; Chen, Y.; Wang, W.-J.; Jin, K.-X.; Wang, X.; Huang, C.; Fu, Y.; Ge, X.; Song, S.; Jeong, H. S.; Yanagisawa, H.; Niu, Y.; Jia, G.; Wu, W.; Tong, W.-M.; Okamoto, A.; He, C.; Danielsen, J. M.; Wang, X.
- Journal Title
  
  Cell Res.
  
  Volume: 24 Pages: 1403-1419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03342
[Journal Article] Visualization of Nucleic Acids with Synthetic Excitation-Controlled Fluorescent Oligonucleotide Probes2014
- Author(s)
  Wang, D. O.; Okamoto, A.
- Journal Title
  
  Methods Mol. Biol.
  
  Volume: 1262 Pages: 69-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26620129
[Journal Article] Sequence-specific microscopic visualization of DNA methylation status at satelliterepeats in individual cell nuclei and chromosomes2013
- Author(s)
  Li, Y. ; Miyanari, Y. ; Shirane, K. ; Nitta, H. ; Kubota, T. ; Ohashi, H. ; Okamoto, A. ; Sasaki, H.
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 41-19 Issue: 19 Pages: e186-e186
- DOI
  10.1093/nar/gkt766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03342
[Journal Article] Application of caged fluorescent nucleotides to live-cell RNA imaging2013
- Author(s)
  Okamoto, A.
- Journal Title
  
  Methods Mol. Biol.
  
  Volume: 1039 Pages: 303-318
- DOI
  10.1007/978-1-62703-535-4_24
- ISBN
  9781627035347, 9781627035354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03342
[Journal Article] Probe Design for Effective Fluorescent Imaging of Intracellular RNA2013
- Author(s)
  Hayashi, G. ; Okamoto, A.
- Journal Title
  
  Chem. Rec.
  
  Volume: 13-2 Issue: 2 Pages: 209-217
- DOI
  10.1002/tcr.201200026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03342, KAKENHI-PROJECT-25870186
[Journal Article] A nucleic acid probe labeled with desmethyl thiazole orange : a new type of hybridization-sensitive fluorescent oligonucleotide for live-cell RNA imaging2013
- Author(s)
  Okamoto A, Sugizaki K, Yuki M, Yanagisawa H, Ikeda S, Sueoka T, Hayashi G, Wang DO.
- Journal Title
  
  Org Biomol Chem
  
  Volume: 11(2) Pages: 362-71
- Data Source
  KAKENHI-PROJECT-24650216
[Journal Article] Fluorescent triplex-forming DNA oligonucleotides labeled with a thiazole orange dimer unit2013
- Author(s)
  Ikeda, S. ; Yanagisawa, H. ; Yuki, M. ; Okamoto, A.
- Journal Title
  
  Artif. DNA PNA XNA
  
  Volume: 4-1 Issue: 1 Pages: 19-27
- DOI
  10.4161/adna.24102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03342
[Journal Article] A nucleic acid probe labeled with desmethyl thiazole orange : A new type of hybridization-sensitive fluorescent oligonucleotide for live-cell RNA imaging2013
- Author(s)
  Okamoto, A. ; Sugizaki, K. ; Yuki, M. ; Yanagisawa, H. ; Ikeda, S. ; Sueoka, T. ; Hayashi, G. ; Wang, D. O
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 11-2 Issue: 2 Pages: 362-371
- DOI
  10.1039/c2ob26707a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03342, KAKENHI-PROJECT-24650216, KAKENHI-PROJECT-25870186
[Journal Article] Characterization of the Triplet State of Hybridization-Sensitive DNA Probe by Using Fluorescence Correlation Spectroscopy2013
- Author(s)
  Shin, H. -S. ; Okamoto, A. ; Sako, Y. ; Kim, S. W. ; Kim, S. Y. ; Pack, C. -G.
- Journal Title
  
  J. Phys. Chem. A
  
  Volume: 117-1 Issue: 1 Pages: 27-33
- DOI
  10.1021/jp307018k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03342
[Journal Article] A rapid and effective FISH protocol with hybridization-sensitive fluorescent linear oligo probes2012
- Author(s)
  Wang, D.O., Matsuno, H., Ikeda, S., Nakamura, A., Yanagisawa, H., Hayashi, Y., Okamoto, A.
- Journal Title
  
  RNA
  
  Volume: 18 Issue: 1 Pages: 166-175
- DOI
  10.1261/rna.028431.111
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22110006, KAKENHI-PROJECT-23870016, KAKENHI-PROJECT-24650216
[Journal Article] ECHO probes : fluorescence emission control for nucleic acid imaging.2012
- Author(s)
  Wang DO and Akimitsu Okamoto
- Journal Title
  
  Journal of Photochemistry and Photobiology, C, Photochemistry Reviews
  
  Volume: 13(2) Pages: 112-123
- Data Source
  KAKENHI-PROJECT-24650216
[Journal Article] ECHO probes: Fluorescence emission control for nucleic acid imaging2012
- Author(s)
  Wang, Dan Ohtan; Okamoto, Akimitsu
- Journal Title
  
  J. Photochem. Photobiol. C-Photochem. Rev.
  
  Volume: 13 Issue: 2 Pages: 112-123
- DOI
  10.1016/j.jphotochemrev.2012.03.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24650216
[Journal Article] ECHO-LNA Conjugates : Hybridization-sensitive Fluorescence and its Application to Fluorescent Detection of Various RNA Strands.2010
- Author(s)
  Sugizaki K., Okamoto A.
- Journal Title
  
  Bioconjugate Chem 21(12)
  
  Pages: 2276-2281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300183
[Journal Article] Excitonic interaction : Another photophysical process for fluorescence-controlled nucleic acid sensing.2010
- Author(s)
  Okamoto, A.
- Journal Title
  
  Chem.Rec 10(3)
  
  Pages: 188-196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300183
[Journal Article] Excitonic interaction: Another photophysical process for fluorescence-controlled nucleic acid sensing2010
- Author(s)
  Okamoto, A.
- Journal Title
  
  Chem.Rec.
  
  Volume: 10(3) Pages: 188-196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300183
[Journal Article] Excitonic interaction : Another photophysical process for fluorescence-controlled nucleic acid sensing2010
- Author(s)
  Okamoto, A.
- Journal Title
  
  Chem.Rec.
  
  Volume: 10(3) Pages: 188-196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350083
[Journal Article] Sets of RNA Repeated Tags and Hybridization-Sensitive Fluorescent Probes for Distinct Images of RNA in a Living Cell2010
- Author(s)
  Kubota T.; Ikeda S.; Yanagisawa H.Yuki M.; Okamoto A
- Journal Title
  
  PLoS ONE 5(9)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350083
[Journal Article] Hybridization-sensitive fluorescent DNA probe with self-avoidance ability2010
- Author(s)
  Ikeda S.; Kubota T.; Yuki M.; Yanagisawa H.; Tsuruma S.; Okamoto A
- Journal Title
  
  Org.Biomol.Chem. 8(3)
  
  Pages: 546-551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350083
[Journal Article] Excitonic interaction : Another photophysical process for fluorescence-controlled nucleic acid sensing2010
- Author(s)
  Okamoto A
- Journal Title
  
  Chem.Rec. 10(3)
  
  Pages: 188-196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350083
[Journal Article] Sets of RNA Repeated Tags and Hybridization-Sensitive Fluorescent Probes for Distinct Images of RNA in a Living Cell2010
- Author(s)
  Kubota, T.; Ikeda, S.; Yanagisawa, H.; Yuki, M.; Okamoto, A.
- Journal Title
  
  PLoS ONE
  
  Volume: (9)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300183
[Journal Article] Exciton-Primer Mediated SNP Detection in SmartAmp2 Reactions2010
- Author(s)
  Lezhava A.; Ishidao T.; Ishizu Y.; Naito K.; Hanami T.; Katayama A.; Kogo Y.; Soma T.; Ikeda S.; Murakami K.; Nogawa C.; Itch M.; Mitani Y.; Harbers M.; Okamoto A.; Hayashizaki Y
- Journal Title
  
  Hum.Mutat. 31(2)
  
  Pages: 208-217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350083
[Journal Article] ECHO-LNA Conjugates : Hybridization-sensitive Fluorescence and its Application to Fluorescent Detection of Various RNA Strands2010
- Author(s)
  Sugizaki K.; Okamoto A.
- Journal Title
  
  Bioconjugate Chem. 21(12)
  
  Pages: 2276-2281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350083
[Journal Article] A Probe Containing Two Base-discriminating Fluorescent (BDF) Nucleosides for SNP Typing2010
- Author(s)
  Yoshida Y.; Niwa K.; Yamada K.; Tokeshi M.; Baba Y.; Saito Y.Okamoto A.; Saito I
- Journal Title
  
  Chem. Lett. 39(2)
  
  Pages: 116-117
- NAID
  10027177147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350083
[Journal Article] ECHO-LNA Conjugates : Hybridization-sensitive Fluorescence and its Application to Fluorescent Detection of Various RNA Strands2010
- Author(s)
  Sugizaki, K.; Okamoto, A.
- Journal Title
  
  Bioconjugate Chem.
  
  Volume: (12) Pages: 2276-2281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300183
[Journal Article] Doubly Thiazole Orange-Labeled DNA for Live Cell RNA Imaging2009
- Author(s)
  Kubota T.; Ikeda S.; Okamoto A
- Journal Title
  
  Bull.Chem.Soc.Jpn. 82(1)
  
  Pages: 110-117
- NAID
  10023987643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350083
[Journal Article] Osmium Complexation of Mismatched DNA : Effect of the Bases Adjacent to Mismatched 5-Methylcytosine2009
- Author(s)
  Nomura A.; Tainaka K.; Okamoto A
- Journal Title
  
  Bioconjugate Chem. 20(3)
  
  Pages: 603-607
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350083
[Journal Article] Hybridization-Sensitive Fluorescent Probe for Long-Time Monitoring of Intracellular RNA2009
- Author(s)
  Kubota T.; Ikeda S.; Yanagisawa H.; Yuki M.; Okamoto A
- Journal Title
  
  Bioconjuga to Chem. 20(6)
  
  Pages: 1256-1261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350083
[Journal Article] Doubly thiazole orange-labeled cytidine for functional expansion of a hybridization-sensitive probe2009
- Author(s)
  Ikeda S.; Yuki M.; Yanagisawa H.; Okamoto A
- Journal Title
  
  Tetrahedron Lett. 50(51)
  
  Pages: 7191-7195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350083
[Journal Article] Chemical approach toward efficient DNA methylation analysis2009
- Author(s)
  Okamoto, A.
- Journal Title
  
  Org.Biomol.Chem. 7(1)
  
  Pages: 21-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20014030
[Journal Article] Exciton-Controlled Hybridization-Sensitive Fluorescent Probes: Multicolor Detection of Nucleic Acids Angew.2009
- Author(s)
  Ikeda, S.; Kubota, T.; Yuki, M.; Okamoto, A.
- Journal Title
  
  Chem., Int. Ed. 48(35)
  
  Pages: 6480-6484
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20014030
[Journal Article] Chemical approach toward efficient DNA methylation analysis2009
- Author(s)
  Okamoto A
- Journal Title
  
  Org.Biomol.Chem. 7(1)
  
  Pages: 21-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350083
[Journal Article] Photoresponsive Tandem Zinc Finger Peptide2009
- Author(s)
  Nomura A.; Okamoto A
- Journal Title
  
  Chem.Commun.
  
  Pages: 1906-1908
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350083
[Journal Article] Chemical approach toward efficient DNA methylation analysis2009
- Author(s)
  Okamoto, A.
- Journal Title
  
  Org.Biomol.Chem. 7(1)
  
  Pages: 21-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350083
[Journal Article] Chemical approach toward efficient DNA methylation analysis2009
- Author(s)
  Okamoto, A.
- Journal Title
  
  Org.Biomol.Chem. 7(1)
  
  Pages: 21-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20655039
[Journal Article] Synthesis and Use of Osmium-DNA Complexes2009
- Author(s)
  Okamoto, A.
- Journal Title
  
  J. Synth. Org. Chem. Jpn. 67(7)
  
  Pages: 680-686
- NAID
  10025399170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20014030
[Journal Article] Doubly thiazole orange-labeled cytidine for functional expansion of a hybridization-sensitive probe2009
- Author(s)
  Ikeda, S.; Yuki, M.; Yanagisawa, H.; Okamoto, A.
- Journal Title
  
  Tetrahedron Lett 50(51)
  
  Pages: 7191-7195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20014030
[Journal Article] Chemical approach toward efficient DNA methylation analysis2009
- Author(s)
  Okamoto, A.
- Journal Title
  
  Org. Biomol. Chem. 7(1)
  
  Pages: 21-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20014030
[Journal Article] Hybridization-Sensitive Fluorescent Probe for Long-Term Monitoring of Intracellular RNA2009
- Author(s)
  Kubota, T.; Ikeda, S.; Yanagisawa, H.; Yuki, M.; Okamoto, A.
- Journal Title
  
  Bioconjugate Chem. 20(6)
  
  Pages: 1256-1261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20014030
[Journal Article] Exciton-Controlled Hybridization- Sensitive Fluorescent Probes : Multicolor Detection of Nucleic Acids2009
- Author(s)
  Ikeda S.; Kubota T.; Yuki M.; Okamoto A
- Journal Title
  
  Angew.Chem., Int.Ed. 48(35)
  
  Pages: 6480-6484
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350083
[Journal Article] Hybridization-Sensitive On-Off DNA Probe: Application of the Exciton Coupling Effect to Effective Fluorescence Quenching Chem.2008
- Author(s)
  Ikeda, S.; Okamoto, A.
- Journal Title
  
  Asian J. 3(6)
  
  Pages: 958-968
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20014030
[Journal Article] Design of a pyrene-containing fluorescence probe for labeling of RNA poly(A) tracts2008
- Author(s)
  Tanaka K.; Okamoto A
- Journal Title
  
  Bioorg.Med.Chem. 16(1)
  
  Pages: 400-404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350083
[Journal Article] Heterogeneity of osmium oxidation efficiency at consecutive thymines2008
- Author(s)
  Nomura, A.; Okamoto, A.
- Journal Title
  
  Org. Biomol. Chem. 6(21)
  
  Pages: 3905-3907
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20014030
[Journal Article] Heterogeneity of osmium oxidation efficiency at consecutive thymines2008
- Author(s)
  Nomura A.; Okamoto A
- Journal Title
  
  Org.Biomol.Chem. 6(21)
  
  Pages: 3905-3907
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350083
[Journal Article] Chemical approach toward efficient DNA methylation analysis2008
- Author(s)
  Okamoto, A.
- Journal Title
  
  Org. Biomol. Chem. 7(1)
  
  Pages: 21-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20655039
[Journal Article] Sequence Dependence of Fluorescence Emission and Quenching of Doubly Thiazole Orange-Labeled DNA : Effective Design of a Hybridization-Sensitive Probe2008
- Author(s)
  Ikeda S.; Kubota T.; Kino K.; Okamoto A
- Journal Title
  
  Bioconjugate Chem. 19(8)
  
  Pages: 1719-1725
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350083
[Journal Article] Hybridization-Sensitive On-Off DNA Probe : Application of the Exciton Coupling Effect to Effective Fluorescence Quenching2008
- Author(s)
  Ikeda S.; Okamoto A
- Journal Title
  
  Chem.Asian J. 3(6)
  
  Pages: 958-968
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350083
[Journal Article] Synthesis and characterization of the 5-methyl-2'-deoxycytidine glycol-dioxoosmium-bipyridine ternary complex in DNA Org.2008
- Author(s)
  Umemoto, T.; Okamoto, A.
- Journal Title
  
  Biomol. Chem. 6(2)
  
  Pages: 269-271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20014030
[Journal Article] Synthesis of Bipyridine-Adenine Conjugates for Methylation Analysis Coll.2008
- Author(s)
  Tainaka, K.; Okamoto, A.
- Journal Title
  
  Symp. Ser. 10
  
  Pages: 146-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20014030
[Journal Article] Synthesis and characterization of the 5-methyl-2'-deoxycytidine glycol-dioxoosmium-bipyridine ternary complex in DNA2008
- Author(s)
  Umemoto T.; Okamoto A
- Journal Title
  
  Org.Biomol.Chem. 6(2)
  
  Pages: 269-271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350083
[Journal Article] Chemical approach toward efficient DNA methylation analysis2008
- Author(s)
  Okamoto, A.
- Journal Title
  
  Org. Biomol. Chem. 7(1)
  
  Pages: 21-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20350083
[Journal Article] Sequence Dependence of Fluorescence Emission and Quenching of Doubly Thiazole Orange-Labeled DNA2008
- Author(s)
  Ikeda, S.; Kubota, T.; Kino, K.; Okamoto, A.
- Journal Title
  
  Effective Design of a Hybridization-Sensitive Probe Bioconjugate Chem. 19(8)
  
  Pages: 1719-1725
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20014030
[Journal Article] Synthesis and fluorescence properties of dimethylaminonaphthalene-deoxyuridine conjugates as micropolarity-sensitive probes2007
- Author(s)
  Okamoto, A.
- Journal Title
  
  Tetrahedron 63(17)
  
  Pages: 3465-3470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18014012
[Journal Article] DNA methylation analysis using metal complex formation2007
- Author(s)
  Okamoto, A.
- Journal Title
  
  Nucleic Acids Symp. Ser. 51(1)
  
  Pages: 27-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18014012
[Journal Article] 5-Methylcytosine-Selective Osmium Oxidation2007
- Author(s)
  Okamoto, A.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids 26(10-12)
  
  Pages: 1601-1604
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18014012
[Journal Article] Simple SNP typing assay using a base-discriminating fluorescent probe2006
- Author(s)
  Okamoto, A.
- Journal Title
  
  Mol. BioSyst. 2 (2)
  
  Pages: 122-127
- Data Source
  KAKENHI-PROJECT-17685018
[Journal Article] DNA hole transport : application to effective photoelectrochemical SNP typing2006
- Author(s)
  Okamoto, A.
- Journal Title
  
  J. Am. Chem. Soc. 128 (2)
  
  Pages: 658-662
- Data Source
  KAKENHI-PROJECT-17685018
[Journal Article] Sequence-selective osmium oxidation of DNA : Efficient distinction between 5-methylcytosine and cytosine2006
- Author(s)
  Okamoto, A.
- Journal Title
  
  Org. Biomol. Chem. 4 (9)
  
  Pages: 1638-1640
- Data Source
  KAKENHI-PROJECT-17685018
[Journal Article] Nile Red nucleoside : Design of a solvatofluorochromic nucleoside as an indicator of micropolarity around DNA2006
- Author(s)
  Okamoto, A.
- Journal Title
  
  J. Org. Chem. 71 (9)
  
  Pages: 3592-3598
- Data Source
  KAKENHI-PROJECT-17685018
[Journal Article] Sequence-selective osmium oxidation of DNA : Efficient distinction between 5-methylcytosine and cytosine2006
- Author(s)
  Okamoto, A.
- Journal Title
  
  Org. Biomol. Chem. 4 (9)
  
  Pages: 1638-1640
- Data Source
  KAKENHI-PROJECT-18014012
[Journal Article] Simple SNP typing assay using a base-discriminating fluorescent probe2006
- Author(s)
  Okamoto, A.
- Journal Title
  
  Mol. BioSyst. 2 (2)
  
  Pages: 122-127
- Data Source
  KAKENHI-PROJECT-18014012
[Journal Article] Nile Red nucleoside : Design of a solvatofluorochromic nucleoside as an indicator of micropolarity around DNA2006
- Author(s)
  Okamoto, A.
- Journal Title
  
  J. Org. Chem. 71 (9)
  
  Pages: 3592-3598
- Data Source
  KAKENHI-PROJECT-18014012
[Journal Article] DNA hole transport : Application to effective photoelectrochemical SNP typing2006
- Author(s)
  A.Okamoto, T.Kamei, I.Saito
- Journal Title
  
  J.Am.Chem.Soc. 128・2
  
  Pages: 658-658
- Data Source
  KAKENHI-PROJECT-17015024
[Journal Article] DNA hole transport : Application to effective photoelectrochemical SNP typing2006
- Author(s)
  A.Okamoto, T.Kamei, I.Saito
- Journal Title
  
  J.Am.Chem.Soc. 128・2
  
  Pages: 658-658
- Data Source
  KAKENHI-PROJECT-17685018
[Journal Article] DNA hole transport : application to effective photoelectrochemical SNP typing2006
- Author(s)
  Okamoto, A.
- Journal Title
  
  J. Am. Chem. Soc. 128 (2)
  
  Pages: 658-662
- Data Source
  KAKENHI-PROJECT-18014012
[Journal Article] DNA hole transport : Application to effective photoelectrochemical SNP typing2006
- Author(s)
  A.Okamoto, T.Kamei, I.Saito
- Journal Title
  
  J.Am.Chem.Soc. 128・2
  
  Pages: 658-658
- Data Source
  KAKENHI-PROJECT-17019033
[Journal Article] Synthesis of highly functional nucleic acids and their application to DNA technology2005
- Author(s)
  A.Okamoto
- Journal Title
  
  Bull.Chem.Soc.Jpn. 78・12
  
  Pages: 2083-2083
- NAID
  10017074159
- Data Source
  KAKENHI-PROJECT-17015024
[Journal Article] Stable, specific, and reversible base pairing via Schiff base2005
- Author(s)
  C.Dohno, A.Okamoto, I.Saito
- Journal Title
  
  J.Am.Chem.Soc 127・47
  
  Pages: 16681-16681
- Data Source
  KAKENHI-PROJECT-17685018
[Journal Article] A dielectric-sensitive fluorescent DNA probe for monitoring polarities an the interior of a DNA-binding protein2005
- Author(s)
  A.Okamoto, K.Tainaka, I.Saito
- Journal Title
  
  Bioconjugate Chem. 16・5
  
  Pages: 1105-1105
- Data Source
  KAKENHI-PROJECT-17019033
[Journal Article] Synthesis of highly functional nucleic acids and their application to DNA technology2005
- Author(s)
  A.Okamoto
- Journal Title
  
  Bull.Chem.Soc.Jpn. 78・12
  
  Pages: 2083-2083
- NAID
  10017074159
- Data Source
  KAKENHI-PROJECT-17019033
[Journal Article] Design of base-discriminating fluorescent nucleosides2005
- Author(s)
  A.Okamoto, Y.Saito, I.Saito
- Journal Title
  
  J.Photochem.Photobiol.C 6・2-3
  
  Pages: 108-108
- NAID
  10017072328
- Data Source
  KAKENHI-PROJECT-17019033
[Journal Article] A dielectric-sensitive fluorescent DNA probe for monitoring polarities an the interior of a DNA-binding protein2005
- Author(s)
  A.Okamoto, K.Tainaka, I.Saito
- Journal Title
  
  Bioconjugate Chem. 16・5
  
  Pages: 1105-1105
- Data Source
  KAKENHI-PROJECT-17685018
[Journal Article] A dielectric-sensitive fluorescent DNA probe for monitoring polarities an the interior of a DNA-binding protein2005
- Author(s)
  A.Okamoto, K.Tainaka, I.Saito
- Journal Title
  
  Bioconjugate Chem. 16・5
  
  Pages: 1105-1105
- Data Source
  KAKENHI-PROJECT-17015024
[Journal Article] Design of base-discrilninating fluorescent nucleosides2005
- Author(s)
  A.Okamoto, Y.Saito, I.Saito
- Journal Title
  
  J.Photochem.Photobiol.C 6・2-3
  
  Pages: 108-108
- Data Source
  KAKENHI-PROJECT-17685018
[Journal Article] Monitoring DNA structures by dual fluorescence of pyrene derivatives2005
- Author(s)
  A.Okamoto, K.Tainaka, K.-i.Nishiza, I.Saito
- Journal Title
  
  J.Am.Chem.Soc. 127・38
  
  Pages: 13128-13128
- Data Source
  KAKENHI-PROJECT-17019033
[Journal Article] Design of base-discriminating fluorescent nucleosides2005
- Author(s)
  A.Okamoto, Y.Saito, I.Saito
- Journal Title
  
  J.Photochem.Photobiol.C 6・2-3
  
  Pages: 108-108
- NAID
  10017072328
- Data Source
  KAKENHI-PROJECT-17015024
[Journal Article] Monitoring DNA structures by dual fluorescence of pyrene derivatives2005
- Author(s)
  A.Okamoto, K.Tainaka, K.-i.Nishiza, I.Saito
- Journal Title
  
  J.Am.Chem.Soc. 127・38
  
  Pages: 13128-13128
- Data Source
  KAKENHI-PROJECT-17685018
[Journal Article] Stable, specific, and reversible base pairing via Schiff base2005
- Author(s)
  C.Dohno, A.Okamoto, I.Saito
- Journal Title
  
  J.Am.Chem.Soc. 127・47
  
  Pages: 16681-16681
- Data Source
  KAKENHI-PROJECT-17019033
[Journal Article] Synthesis of highly functional nucleic acids and their application to DNA technology2005
- Author(s)
  A.Okamoto
- Journal Title
  
  Bull.Chem.Soc.Jpn. 78・12
  
  Pages: 2083-2083
- NAID
  10017074159
- Data Source
  KAKENHI-PROJECT-17685018
[Journal Article] Monitoring DNA structures by dual fluorescence of pyrene derivatives2005
- Author(s)
  A.Okamoto, K.Tainaka, K.-i.Nishiza, I.Saito
- Journal Title
  
  J.Am.Chem.Soc. 127・38
  
  Pages: 13128-13128
- Data Source
  KAKENHI-PROJECT-17015024
[Journal Article] Stable, specific, and reversible ease pairing via Schiff base2005
- Author(s)
  C.Dohno, A.Okamoto, I.Saito
- Journal Title
  
  J.Am.Chem.Soc. 127・47
  
  Pages: 16681-16681
- Data Source
  KAKENHI-PROJECT-17015024
[Journal Article] Pyrene-labeled Base-discriminating Fluorescent DNA Probes for Homogeneous SNP Typing2004
- Author(s)
  Okamoto, A., Kanatani, K., Saito, I.
- Journal Title
  
  Journal of the American Chemical Society 126・15
  
  Pages: 4820-4827
- Data Source
  KAKENHI-PROJECT-16011231
[Journal Article] Synthesis and properties of novel base-discriminating fluorescent (BDF) nucleosides : A highly polarity-sensitive fluorophore for SNP typing2004
- Author(s)
  Saito, Y., Miyauchi, Y., Okamoto, A., Saito, I.
- Journal Title
  
  Tetrahedron Letters 45・42
  
  Pages: 7827-7831
- Data Source
  KAKENHI-PROJECT-16011231
[Journal Article] A nucleobase that releases reporter tags upon DNA oxidation2004
- Author(s)
  Okamoto, A., Tanaka, K., Saito, I.
- Journal Title
  
  Journal of the American Chemical Society 126・2
  
  Pages: 416-417
- Data Source
  KAKENHI-PROJECT-16011231
[Journal Article] Cytosine Detection by a Fluorescein-labeled Probe Containing Base-discriminating Fluorescent Nucleobase2004
- Author(s)
  Okamoto A., Tanaka, K., Fukuta, T., Saito, I.
- Journal Title
  
  ChemBioChem 5・7
  
  Pages: 958-963
- Data Source
  KAKENHI-PROJECT-16011231
[Journal Article] Pyrene-labeled Oligodeoxynucleotide Probe for Detecting Base Insertion by Excimer Fluorescence Emission2004
- Author(s)
  Okamoto, A., Ichiba, T., Saito, I.
- Journal Title
  
  Journal of the American Chemical Society 126・27
  
  Pages: 8364-8365
- Data Source
  KAKENHI-PROJECT-16011231
[Journal Article] Base-Discriminating Fluorescent (BDF) Nucleoside : Distinction of Thymine by Fluorescence Quenching2004
- Author(s)
  Saito, Y., Miyauchi, Y., Okamoto, A., Saito, I.
- Journal Title
  
  Chemical Communications 2004・15
  
  Pages: 1704-1705
- Data Source
  KAKENHI-PROJECT-16011231
[Patent] 光増感色素2020
- Inventor(s)
  岡本晃充、出羽和歌子、浜窪隆雄、戸田奈緒子、須藤幸夫
- Industrial Property Rights Holder
  岡本晃充、出羽和歌子、浜窪隆雄、戸田奈緒子、須藤幸夫
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-108318
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-18H03931
[Patent] ヌクレオチド標識試薬およびそれが導入されたオリゴヌクレオチド誘導体2007
- Inventor(s)
  岡本晃充
- Industrial Property Rights Holder
  理化学研究所
- Industrial Property Number
  2007-246253
- Filing Date
  2007-09-21
- Data Source
  KAKENHI-PROJECT-18014012
[Presentation] がん細胞選択的なヘテロ二重鎖核酸構築による細胞毒性の発現2024
- Author(s)
  原田直毅、森廣邦彦、岡本晃充
- Organizer
  日本薬学会第１４４年会
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] 細胞の表現型と内部分子発現を対応付ける高集積１細胞アレイ解析法の開発2024
- Author(s)
  梅田侑生、山口哲志、岡本晃充
- Organizer
  化学工学会第89年会
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] 化学修飾が長鎖DNA二重鎖の細胞毒性に与える影響2024
- Author(s)
  馬場愛奈美、森廣邦彦、岡本晃充
- Organizer
  日本薬学会第１４４年会
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] DNAナノテクノロジーCatalytic hairpin assembly (CHA) を応用したプロドラッグDNAデコイの開発2024
- Author(s)
  安田壮秀、森廣邦彦、岡本晃充
- Organizer
  日本化学会第１０４春季年会
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] 不均一鎖の近位ユビキチンC末端への多様な化学修飾の導入2024
- Author(s)
  古畑隆史、崔汎圭、宇野大輝、佐藤裕介、尾勝圭、深井周也、岡本晃充
- Organizer
  日本化学会第１０４春季年会
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] 化学修飾が長鎖DNA二重鎖の細胞毒性に与える影響2024
- Author(s)
  馬場愛奈美、森廣邦彦、岡本晃充
- Organizer
  日本薬学会第１４４年会
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] Assembly of nucleic acids kills cancer2024
- Author(s)
  Akimitsu Okamoto
- Organizer
  Supra FIBER International Summit for Nucleic Acids (S-FISNA)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] 生細胞内の多種マイクロRNAの同時検出2024
- Author(s)
  徐云嵩、森廣邦彦、岡本晃充
- Organizer
  日本化学会第１０４春季年会
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] GALAペプチドとカチオン性脂質による嵩高いケージドタンパク質の細胞内導入2024
- Author(s)
  守山千晴、山本涼太郎、芝原優希、中瀬生彦、岡本晃充、山口哲志
- Organizer
  化学工学会第89年会
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] 弱酸性微小環境応答性人工核酸塩基を用いたがん選択的DNAアプタマーの開発2024
- Author(s)
  陳鈺媛、森廣邦彦、根本祐衣、市村晃人、植木亮介、山東信介、岡本晃充
- Organizer
  日本化学会第１０４春季年会
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] オキシム連結反応を用いた不均一ポリユビキチン鎖の構造制御合成2024
- Author(s)
  篠原陵大、古畑隆史、山田征吾、岡本晃充
- Organizer
  日本化学会第１０４春季年会
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] 不均一鎖の近位ユビキチンC末端への多様な化学修飾の導入2024
- Author(s)
  古畑隆史、崔汎圭、宇野大輝、佐藤裕介、尾勝圭、深井周也、岡本晃充
- Organizer
  日本化学会第１０４春季年会
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] Anticancer effects of nulcleic acid aggregates2024
- Author(s)
  Akimitsu Okamoto
- Organizer
  11th Annual Oligonucleotide Networking Event
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] 腫瘍関連miRNAが触媒するDNAデコイの腫瘍細胞内生成2024
- Author(s)
  安田壮秀、森廣邦彦、岡本晃充
- Organizer
  日本薬学会第１４４年会
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] 嵩高いケージングを施した酵素を用いた培養基材の光分解2024
- Author(s)
  山本涼太郎、山口哲志、岡本晃充
- Organizer
  化学工学会第89年会
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] Anticancer effects of nulcleic acid aggregates2024
- Author(s)
  Akimitsu Okamoto
- Organizer
  11th Annual Oligonucleotide Networking Event
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] 生細胞内の多種マイクロRNAの同時検出2024
- Author(s)
  徐云嵩、森廣邦彦、岡本晃充
- Organizer
  日本化学会第１０４春季年会
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] GALAペプチドとカチオン性脂質による嵩高いケージドタンパク質の細胞内導入2024
- Author(s)
  守山千晴、山本涼太郎、芝原優希、中瀬生彦、岡本晃充、山口哲志
- Organizer
  化学工学会第89年会
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] タンパク質分解経路の制御を指向した新規ケミカルノックダウン法の確立2024
- Author(s)
  吉田和生、古畑隆史、土屋光、佐伯泰、岡本晃充
- Organizer
  日本薬学会第１４４年会
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] オキシム連結反応を用いた不均一ポリユビキチン鎖の構造制御合成2024
- Author(s)
  篠原陵大、古畑隆史、山田征吾、岡本晃充
- Organizer
  日本化学会第１０４春季年会
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] 弱酸性微小環境応答性人工核酸塩基を用いたがん選択的DNAアプタマーの開発2024
- Author(s)
  陳鈺媛、森廣邦彦、根本祐衣、市村晃人、植木亮介、山東信介、岡本晃充
- Organizer
  日本化学会第１０４春季年会
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] がん細胞選択的なヘテロ二重鎖核酸構築による細胞毒性の発現2024
- Author(s)
  原田直毅、森廣邦彦、岡本晃充
- Organizer
  日本薬学会第１４４年会
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] Assembly of nucleic acids kills cancer2024
- Author(s)
  Akimitsu Okamoto
- Organizer
  Supra FIBER International Summit for Nucleic Acids (S-FISNA)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] 細胞の表現型と内部分子発現を対応付ける高集積１細胞アレイ解析法の開発2024
- Author(s)
  梅田侑生、山口哲志、岡本晃充
- Organizer
  化学工学会第89年会
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] 光分解型ゲル薄膜上での1細胞画像解析と細胞の選択的光選別2024
- Author(s)
  李雪陽、山口哲志、岡本晃充
- Organizer
  化学工学会第89年会
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] DNAナノテクノロジーCatalytic hairpin assembly (CHA) を応用したプロドラッグDNAデコイの開発2024
- Author(s)
  安田壮秀、森廣邦彦、岡本晃充
- Organizer
  日本化学会第１０４春季年会
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] 光分解型ゲル薄膜上での1細胞画像解析と細胞の選択的光選別2024
- Author(s)
  李雪陽、山口哲志、岡本晃充
- Organizer
  化学工学会第89年会
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] 嵩高いケージングを施した酵素を用いた培養基材の光分解2024
- Author(s)
  山本涼太郎、山口哲志、岡本晃充
- Organizer
  化学工学会第89年会
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] 腫瘍関連miRNAが触媒するDNAデコイの腫瘍細胞内生成2024
- Author(s)
  安田壮秀、森廣邦彦、岡本晃充
- Organizer
  日本薬学会第１４４年会
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] タンパク質分解経路の制御を指向した新規ケミカルノックダウン法の確立2024
- Author(s)
  吉田和生、古畑隆史、土屋光、佐伯泰、岡本晃充
- Organizer
  日本薬学会第１４４年会
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] マイクロRNAが触媒するデコイ核酸医薬の腫瘍細胞内生成2023
- Author(s)
  安田壮秀、森廣邦彦、岡本晃充
- Organizer
  日本薬学会第１４３年会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] Oncolytic Hairpin DNA Pairs2023
- Author(s)
  Akimitsu Okamoto
- Organizer
  TIDES USA 2023
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] マイクロRNAが触媒するデコイ核酸医薬の腫瘍細胞内生成2023
- Author(s)
  安田壮秀、森廣邦彦、岡本晃充
- Organizer
  日本薬学会第１４３年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] がん細胞選択的なDNA/RNAヘテロ二重鎖の構築2023
- Author(s)
  原田　直毅、森廣　邦彦、岡本　晃充
- Organizer
  日本核酸医薬学会第8回年会
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] miRNA応答型低分子薬剤放出システム2023
- Author(s)
  冨田康弘、岡本晃充、森廣邦彦
- Organizer
  第１６回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] Production of DNA decoy catalyzed with microDNA only in deseased cells2023
- Author(s)
  Soshu Yasuda, Kunihiko Morihiro, Akimitsu Okamoto
- Organizer
  18th Annual Meeting of the Oligonucleotide Therapeutics Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] Oncolytic hairpin DNA pairs2023
- Author(s)
  Akimitsu Okamoto
- Organizer
  A3RONA 2023 Chengdu
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] 細胞間相互作用を創出する生体直交的な光反応性表面2023
- Author(s)
  山口哲志、小阪高広、山平真也、岡本晃充
- Organizer
  化学工学会第88年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 細胞間接触を可視化する化学酵素的標識法2023
- Author(s)
  山口哲志、池田諒佑、岡本晃充
- Organizer
  化学工学会第88年会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] 画像解析による1細胞分取のための光応答性ゲル薄膜の開発2023
- Author(s)
  李雪陽、山口哲志、上原廉二朗、山平真也、岡本晃充
- Organizer
  第７１回高分子討論会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] Drug Strategies for Selective Cancer Tratment Using Stimuli-Responsive Artificial Nucleic Acid2023
- Author(s)
  Yasuhiro Tomida, Kunihiko Morihiro, Akimitsu Okamoto
- Organizer
  第50回国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] Activation of siRNA triggered by copper ion accumulated in cancer cells2023
- Author(s)
  Yasuhiro Tomida, Honami Ando, Kunihiko Morihiro, Akimitsu Okamoto
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] がん選択的な免疫療法を可能にするヘアピン型DNA医薬2023
- Author(s)
  森廣邦彦、大住拓輝、岡本晃充
- Organizer
  日本核酸医薬学会　第７回年会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] Development of multidrug-integrated mini-nucleic acid drugs for effective chemotherapy of refractory cancer2023
- Author(s)
  Ryosei Komiyama, Kunihiko Morihiro, Akimitsu Okamoto
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] マイクロRNAが触媒する病変細胞選択的なDNAデコイ生成2023
- Author(s)
  安田壮秀、森廣邦彦、岡本晃充
- Organizer
  日本核酸医薬学会　第７回年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 連結方向切り替え可能な One-Potペプチド連結法によるタンパク質化学合成2023
- Author(s)
  中津幸輝、岡本晃充、林剛介、村上裕
- Organizer
  第１６回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 嵩高いケージング法を用いた生命活動の光制御2023
- Author(s)
  山口哲志、山本涼太郎、岡本晃充
- Organizer
  化学工学会第54回秋季大会
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] 光応答性細胞固定化表面を用いた免疫細胞の1細胞傷害性解析2023
- Author(s)
  山口哲志、小阪高広、山平真也、岡本晃充
- Organizer
  高分子学会　第32回バイオ高分子シンポジウム
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] Oncolytic Hairpin Nucleic Acid Pairs2023
- Author(s)
  Akimitsu Okamoto
- Organizer
  19th Annual Meeting of the Oligonucleotide Therapeutics Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] 近赤外線光化学インターナリゼーション　免疫毒素の効率的な細胞内デリバリーを目指した歪んだ亜鉛フタロシアニンの設計2023
- Author(s)
  岡本　晃充
- Organizer
  第４５回日本光医学・光生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] Chemical regulation of degradative fate of protein by indirect ubiquitination2023
- Author(s)
  Kazuki Yoshida, Ryoka Fujita, Takafumi Furuhata, Akimitsu Okamoto
- Organizer
  第60回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] がん診断に向けた多種マイクロRNAの同時蛍光検出2023
- Author(s)
  徐云嵩、森廣邦彦、岡本晃充
- Organizer
  日本薬学会第１４３年会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] Multidrug-integrated mini-nucleic acid drug platform for effective chemotherapy of refractory cancer2023
- Author(s)
  Ryosei Komiyama, Kunihiko Morihiro, Akimitsu Okamoto
- Organizer
  第50回国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] 光分解性タンパク質-高分子ハイブリッド材料を用いた細胞のケーシング2023
- Author(s)
  山口哲志、中条一貴、岡本晃充
- Organizer
  第７１回高分子討論会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] Tumor immune activation through intracellular hairpin DNA assenbly2023
- Author(s)
  Kunihiko Morihiro, Hiraki Osumi, Akimitsu Okamoto
- Organizer
  18th Annual Meeting of the Oligonucleotide Therapeutics Society
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] Production of DNA decoy catalyzed with microDNA only in deseased cells2023
- Author(s)
  Soshu Yasuda, Kunihiko Morihiro, Akimitsu Okamoto
- Organizer
  18th Annual Meeting of the Oligonucleotide Therapeutics Society
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 細胞内部の膜タンパク質の定量的1細胞解析法の開発2023
- Author(s)
  梅田侑生、山口哲志、山平真也、中村元直、岡本晃充
- Organizer
  第１６回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] ペプチド型ユビキチンリガンドキメラを用いた標的タンパク質分解2023
- Author(s)
  宮本丈太郎、古畑隆史、岡本晃充
- Organizer
  第34回生体機能関連化学部会若手の会サマースクール
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] トキシン結合型セツキシマブと光線力学療法の併用による低侵襲新規治療法の可能性について.2023
- Author(s)
  小松紀子, 黒田実可子, 高才東, 星和人, 岡本晃充, 浜窪隆雄, 安部貴大
- Organizer
  第1回日本低侵襲口腔がん治療学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-23K09344
[Presentation] がん診断に向けた多種マイクロRNAの同時蛍光検出2023
- Author(s)
  徐云嵩、森廣邦彦、岡本晃充
- Organizer
  日本薬学会第１４３年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] Oncolytic Hairpin DNA Pairs2023
- Author(s)
  Akimitsu Okamoto
- Organizer
  TIDES USA 2023
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] トキシン結合型セツキシマブと光線力学療法の併用は頭頸部扁平上皮癌細胞株に対して抗腫瘍効果を高めるか.2023
- Author(s)
  小松紀子, 黒田実可子, 高才東, 星和人, 浜窪隆雄, 岡本晃充, 安部貴大
- Organizer
  第77回NPO法人日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-23K09344
[Presentation] がん関連マイクロRNAが触媒する腫瘍細胞選択的なデコイ核酸医薬生成2023
- Author(s)
  安田壮秀、森廣邦彦、岡本晃充
- Organizer
  第１２回ＣＳＪ化学フェスタ
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] 光分解性タンパク質-高分子ハイブリッド材料を用いた細胞のケーシング2023
- Author(s)
  山口哲志、中条一貴、岡本晃充
- Organizer
  第７１回高分子討論会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 嵩高いケージング法を用いた生命活動の光制御2023
- Author(s)
  山口哲志、山本涼太郎、岡本晃充
- Organizer
  化学工学会第54回秋季大会
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] マイクロRNAが触媒する病変細胞選択的なDNAデコイ生成2023
- Author(s)
  安田壮秀、森廣邦彦、岡本晃充
- Organizer
  日本核酸医薬学会　第７回年会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] 画像観察に基づく1細胞選別のための光応答性細胞付着ゲル薄膜の開発2023
- Author(s)
  李雪陽、山口哲志、岡本晃充
- Organizer
  日本化学会第１０３春季年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 嵩高いケージングを用いた細胞内でのタンパク質の光活性化2023
- Author(s)
  山本涼太郎、山口哲志、岡本晃充
- Organizer
  日本化学会第１０３春季年会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] Evaluation of biochemical properties of nucleosome formed by short interspersed nuclear element2023
- Author(s)
  Yijing Lin, Takafumi Furuhata, Akimitsu Okamoto
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] RNAヘアピン技術によるがん選択的な細胞毒性2023
- Author(s)
  森田駿人、森廣邦彦、岡本晃充
- Organizer
  第１６回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] miR-21 detection technology based on HCR and ECHO probe2023
- Author(s)
  Yunsong Xu, Kunihiko Morihiro, Akimitsu Okamoto
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] 難治性がんの効果的な化学療法に向けた多剤一体型ミニ核酸医薬の開発2023
- Author(s)
  込山凌成、森廣邦彦、岡本晃充
- Organizer
  第１６回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] 化学修飾による長鎖ＤＮＡ二重鎖の細胞毒性制御2023
- Author(s)
  馬場愛奈美、森廣　邦彦、岡本　晃充
- Organizer
  日本核酸医薬学会第8回年会
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] Chemical regulation of degradative fate of protein by indirect ubiquitination2023
- Author(s)
  Kazuki Yoshida, Ryoka Fujita, Takafumi Furuhata, Akimitsu Okamoto
- Organizer
  第60回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] トキシン結合型セツキシマブと光線力学療法の併用は頭頸部扁平上皮癌細胞株に対して抗腫瘍効果を高めるか.2023
- Author(s)
  小松紀子, 黒田実可子, 高才東, 星和人, 浜窪隆雄, 岡本晃充, 安部貴大
- Organizer
  第77回NPO法人日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-20K10091
[Presentation] 白金系抗悪性腫瘍剤によるヌクレオソームの物理化学的変化と位置の再組織化2023
- Author(s)
  廖宣宇、古畑隆史、岡本晃充
- Organizer
  日本薬学会第１４３年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 弱酸性微小環境応答性人工核酸を用いたがん選択的DNAアプタマーの開発2023
- Author(s)
  根本祐衣、森廣邦彦、岡本晃充
- Organizer
  第１２回ＣＳＪ化学フェスタ
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] 連結方向切り替え可能な One-Potペプチド連結法によるタンパク質化学合成2023
- Author(s)
  中津幸輝、岡本晃充、林剛介、村上裕
- Organizer
  第１６回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] がん選択的な免疫療法を可能にするヘアピン型DNA医薬2023
- Author(s)
  森廣邦彦、大住拓輝、岡本晃充
- Organizer
  日本核酸医薬学会　第７回年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] がん関連マイクロRNAが触媒する腫瘍細胞選択的なデコイ核酸医薬生成2023
- Author(s)
  安田壮秀、森廣邦彦、岡本晃充
- Organizer
  第１２回ＣＳＪ化学フェスタ
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 嵩高いケージングを用いた細胞内でのタンパク質の光活性化2023
- Author(s)
  山本涼太郎、山口哲志、岡本晃充
- Organizer
  日本化学会第１０３春季年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 連結方向切り替え可能なone-potペプチド連結法を用いたタンパク質化学合成2023
- Author(s)
  中津幸輝、岡本晃充、林剛介、村上裕
- Organizer
  第１２回ＣＳＪ化学フェスタ
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 連結方向切り替え可能なone-potペプチド連結法を用いたタンパク質化学合成2023
- Author(s)
  中津幸輝、岡本晃充、林剛介、村上裕
- Organizer
  第１２回ＣＳＪ化学フェスタ
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] 腫瘍溶解性ヘアピン DNAペア：マイクロ RNA駆動型 DNA自己組織化を介した選択的細胞毒性誘導剤2023
- Author(s)
  森廣邦彦、大住拓輝、岡本晃充
- Organizer
  第１６回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] がん細胞内に蓄積された銅イオンをトリガーとするsiRNAの活性化2023
- Author(s)
  冨田康弘、森廣邦彦、岡本晃充
- Organizer
  日本化学会第１０３春季年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] Evaluation of biochemical properties of nucleosome formed by short interspersed nuclear element2023
- Author(s)
  Yijing Lin, Takafumi Furuhata, Akimitsu Okamoto
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] がん細胞内に蓄積された銅イオンをトリガーとするsiRNAの活性化2023
- Author(s)
  冨田康弘、森廣邦彦、岡本晃充
- Organizer
  日本化学会第１０３春季年会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] Oncolytic Hairpin DNA Pairs2023
- Author(s)
  Akimitsu Okamoto
- Organizer
  Nucleosides, Nucleotides and Oligonucleotides (GRS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] トキシン結合型セツキシマブと光線力学療法の併用はセツキシマブを超えるか.2023
- Author(s)
  小松紀子, 黒田実可子, 高才東, 星和人, 岡本晃充, 浜窪隆雄, 安部貴大
- Organizer
  第68回日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-23K09344
[Presentation] 画像解析による1細胞分取のための光応答性ゲル薄膜の開発2023
- Author(s)
  李雪陽、山口哲志、上原廉二朗、山平真也、岡本晃充
- Organizer
  第７１回高分子討論会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] Drug Strategies for Selective Cancer Tratment Using Stimuli-Responsive Artificial Nucleic Acid2023
- Author(s)
  Yasuhiro Tomida, Kunihiko Morihiro, Akimitsu Okamoto
- Organizer
  第50回国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] Development of multidrug-integrated mini-nucleic acid drugs for effective chemotherapy of refractory cancer2023
- Author(s)
  Ryosei Komiyama, Kunihiko Morihiro, Akimitsu Okamoto
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] Mechanism study of endothelial cell toxicity medeiated by histone H4 via membrane-disrupting peptides2023
- Author(s)
  Zihao Wang, Mikako Hamabe, Takafumi Furuhata, Akimitsu Okamoto
- Organizer
  第60回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] miRNA応答型低分子薬剤放出システム2023
- Author(s)
  冨田康弘、岡本晃充、森廣邦彦
- Organizer
  第１６回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 画像観察に基づく1細胞選別のための光応答性細胞付着ゲル薄膜の開発2023
- Author(s)
  李雪陽、山口哲志、岡本晃充
- Organizer
  日本化学会第１０３春季年会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] miR-21 detection technology based on HCR and ECHO probe2023
- Author(s)
  Yunsong Xu, Kunihiko Morihiro, Akimitsu Okamoto
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] トキシン結合型セツキシマブと光線力学療法の併用による抗腫瘍効果の検討.2023
- Author(s)
  小松紀子, 黒田実可子, 高才東, 星和人, 浜窪隆雄, 岡本晃充, 安部貴大
- Organizer
  第47回日本頭頸部癌学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-23K09344
[Presentation] 難治性がんの効果的な化学療法に向けた多剤一体型短鎖核酸医薬の開発2023
- Author(s)
  込山凌成、森廣邦彦、岡本晃充
- Organizer
  日本化学会第１０３春季年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 嵩高い光分解性保護基を用いたタンパク質の細胞内光活性化2023
- Author(s)
  山本涼太郎、山口哲志、山本一穂、南畑孝介、岡本晃充
- Organizer
  第７１回高分子討論会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 細胞間接触を可視化する化学酵素的標識法2023
- Author(s)
  山口哲志、池田諒佑、岡本晃充
- Organizer
  化学工学会第88年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] RNAヘアピン技術によるがん選択的な細胞毒性2023
- Author(s)
  森田駿人、森廣邦彦、岡本晃充
- Organizer
  日本核酸医薬学会　第７回年会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] 難治性がんの効果的な化学療法に向けた多剤一体型短鎖核酸医薬の開発2023
- Author(s)
  込山凌成、森廣邦彦、岡本晃充
- Organizer
  日本化学会第１０３春季年会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] トキシン結合型セツキシマブと光線力学療法の併用による抗腫瘍効果の検討2023
- Author(s)
  小松紀子, 黒田実可子, 高才東, 星和人, 浜窪隆雄, 岡本晃充, 安部貴大
- Organizer
  第47回日本頭頸部癌学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-20K10091
[Presentation] RNAヘアピン技術によるがん選択的な細胞毒性2023
- Author(s)
  森田駿人、森廣邦彦、岡本晃充
- Organizer
  日本核酸医薬学会　第７回年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 核酸ナノ技術によりがん選択的な細胞毒性を獲得するヘアピン型RNA分子の開発2023
- Author(s)
  森田駿人、森廣邦彦、岡本晃充
- Organizer
  日本薬学会第１４３年会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] Oncolytic hairpin DNA pairs2023
- Author(s)
  Akimitsu Okamoto
- Organizer
  A3RONA 2023 Chengdu
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] Activation of siRNA triggered by copper ion accumulated in cancer cells2023
- Author(s)
  Yasuhiro Tomida, Honami Ando, Kunihiko Morihiro, Akimitsu Okamoto
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] Oncolytic Hairpin DNA Pairs2023
- Author(s)
  Akimitsu Okamoto
- Organizer
  Nucleosides, Nucleotides and Oligonucleotides (GRS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] 嵩高い光分解性保護基を用いたタンパク質の細胞内光活性化2023
- Author(s)
  山本涼太郎、山口哲志、山本一穂、南畑孝介、岡本晃充
- Organizer
  第７１回高分子討論会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] 弱酸性微小環境応答性人工核酸を用いたがん選択的DNAアプタマーの開発2023
- Author(s)
  根本祐衣、森廣邦彦、岡本晃充
- Organizer
  第１２回ＣＳＪ化学フェスタ
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 細胞内部の膜タンパク質の定量的1細胞解析法の開発2023
- Author(s)
  梅田侑生、山口哲志、山平真也、中村元直、岡本晃充
- Organizer
  第１６回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] 細胞間相互作用を創出する生体直交的な光反応性表面2023
- Author(s)
  山口哲志、小阪高広、山平真也、岡本晃充
- Organizer
  化学工学会第88年会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] Mechanism study of endothelial cell toxicity medeiated by histone H4 via membrane-disrupting peptides2023
- Author(s)
  Zihao Wang, Mikako Hamabe, Takafumi Furuhata, Akimitsu Okamoto
- Organizer
  第60回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] がん細胞選択的なDNA/RNAヘテロ二重鎖の構築2023
- Author(s)
  原田　直毅、森廣　邦彦、岡本　晃充
- Organizer
  日本核酸医薬学会第8回年会
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] トキシン結合型セツキシマブと光線力学療法の併用による低侵襲新規治療法の可能性について2023
- Author(s)
  小松紀子, 黒田実可子, 高才東, 星和人, 岡本晃充, 浜窪隆雄, 安部貴大
- Organizer
  第1回日本低侵襲口腔がん治療学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20K10091
[Presentation] 腫瘍溶解性ヘアピン DNAペア：マイクロ RNA駆動型 DNA自己組織化を介した選択的細胞毒性誘導剤2023
- Author(s)
  森廣邦彦、大住拓輝、岡本晃充
- Organizer
  第１６回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] ペプチド型ユビキチンリガンドキメラを用いた標的タンパク質分解2023
- Author(s)
  宮本丈太郎、古畑隆史、岡本晃充
- Organizer
  第34回生体機能関連化学部会若手の会サマースクール
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] Multidrug-integrated mini-nucleic acid drug platform for effective chemotherapy of refractory cancer2023
- Author(s)
  Ryosei Komiyama, Kunihiko Morihiro, Akimitsu Okamoto
- Organizer
  第50回国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] ユビキチン―リガンドキメラペプチドによる標的タンパク質分解2023
- Author(s)
  宮本丈太郎、古畑隆史、岡本晃充
- Organizer
  日本化学会第１０３春季年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 近赤外線光化学インターナリゼーション　免疫毒素の効率的な細胞内デリバリーを目指した歪んだ亜鉛フタロシアニンの設計2023
- Author(s)
  岡本　晃充
- Organizer
  第４５回日本光医学・光生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] Oncolytic Hairpin Nucleic Acid Pairs2023
- Author(s)
  Akimitsu Okamoto
- Organizer
  19th Annual Meeting of the Oligonucleotide Therapeutics Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H00317
[Presentation] 光応答性細胞固定化表面を用いた免疫細胞の1細胞傷害性解析2023
- Author(s)
  山口哲志、小阪高広、山平真也、岡本晃充
- Organizer
  高分子学会　第32回バイオ高分子シンポジウム
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 化学修飾による長鎖ＤＮＡ二重鎖の細胞毒性制御2023
- Author(s)
  馬場愛奈美、森廣　邦彦、岡本　晃充
- Organizer
  日本核酸医薬学会第8回年会
- Data Source
  KAKENHI-PROJECT-23K17969
[Presentation] RNAヘアピン技術によるがん選択的な細胞毒性2023
- Author(s)
  森田駿人、森廣邦彦、岡本晃充
- Organizer
  第１６回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] Tumor immune activation through intracellular hairpin DNA assenbly2023
- Author(s)
  Kunihiko Morihiro, Hiraki Osumi, Akimitsu Okamoto
- Organizer
  18th Annual Meeting of the Oligonucleotide Therapeutics Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] トキシン結合型セツキシマブと光線力学療法の併用はセツキシマブを超えるか2023
- Author(s)
  小松紀子, 黒田実可子, 高才東, 星和人, 岡本晃充, 浜窪隆雄, 安部貴大
- Organizer
  第68回日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-20K10091
[Presentation] 難治性がんの効果的な化学療法に向けた多剤一体型ミニ核酸医薬の開発2023
- Author(s)
  込山凌成、森廣邦彦、岡本晃充
- Organizer
  第１６回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 核酸ナノ技術によりがん選択的な細胞毒性を獲得するヘアピン型RNA分子の開発2023
- Author(s)
  森田駿人、森廣邦彦、岡本晃充
- Organizer
  日本薬学会第１４３年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] ユビキチン―リガンドキメラペプチドによる標的タンパク質分解2023
- Author(s)
  宮本丈太郎、古畑隆史、岡本晃充
- Organizer
  日本化学会第１０３春季年会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] 白金系抗悪性腫瘍剤によるヌクレオソームの物理化学的変化と位置の再組織化2023
- Author(s)
  廖宣宇、古畑隆史、岡本晃充
- Organizer
  日本薬学会第１４３年会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] 光応答性基板を用いた免疫細胞の細胞傷害性のシングルセル解析2022
- Author(s)
  小阪高広、山口哲志、山平真也、岡本晃充
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] Enzymatic branched ubiquitin chain formation on K63 homotypic chain with branched points defined by photo-induced stepwise poly-ubiquitin synthesis2022
- Author(s)
  Phebee Angeline Devadasan Racheal、Takafumi Furuhata、Iori Murayama、Usano Toyoda、Akimitsu Okamoto
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 2-aminobenzamide誘導体によるチアゾリジン開環とone-potペプチド連結法への応用2022
- Author(s)
  中津幸輝、村上裕、林剛介、岡本晃充
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] 刺激分解性ビオチン化試薬を用いた細胞内タンパク質送達2022
- Author(s)
  山本一穂、山口哲志、岡本晃充
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] ユビキチンキメラ分子による転写因子のケミカルノックダウン2022
- Author(s)
  吉田和生、藤田涼香、古畑隆史、岡本晃充
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 光応答性基板を用いた免疫細胞の細胞傷害性のシングルセル解析2022
- Author(s)
  小阪高広、山口哲志、山平真也、岡本晃充
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 刺激分解性ビオチン化試薬を用いた細胞内タンパク質送達2022
- Author(s)
  山本一穂、山口哲志、岡本晃充
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 細胞膜のマイクロ流体剥離技術を用いた細胞内1細胞解析2022
- Author(s)
  山口哲志・梅田侑生・山平真也・岡本晃充
- Organizer
  化学工学会第８７年会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] 低分子リガンド-ユビキチンキメラを用いたタンパク質の間接的ユビキチン化法2022
- Author(s)
  宇野大輝、藤田涼香、古畑隆史、岡本晃充
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] Evaluation of nucleosome structure alteration and accessibility change caused by platinum-based antineoplastics2022
- Author(s)
  Xuanyu LIAO、Takafumi Furuhata、Akimitsu Okamoto、Ikuma Arakaki
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] Indirect ubiquitination for targeted degradation of the transcription factor2022
- Author(s)
  Ryoka Fujita、Takafumi Furuhata、Yuto Matsumura、Tokiha Ozawa、Akimitsu Okamoto
- Organizer
  第４８回国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 低分子リガンド-ユビキチンキメラを用いたタンパク質の間接的ユビキチン化法2022
- Author(s)
  宇野大輝、藤田涼香、古畑隆史、岡本晃充
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 細胞膜のマイクロ流体剥離技術を用いた細胞内1細胞解析2022
- Author(s)
  山口哲志・梅田侑生・山平真也・岡本晃充
- Organizer
  化学工学会第８７年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 2-aminobenzamide誘導体によるチアゾリジン開環とone-potペプチド連結法への応用2022
- Author(s)
  中津幸輝、村上裕、林剛介、岡本晃充
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] Enzymatic branched ubiquitin chain formation on K63 homotypic chain with branched points defined by photo-induced stepwise poly-ubiquitin synthesis2022
- Author(s)
  Phebee Angeline Devadasan Racheal、Takafumi Furuhata、Iori Murayama、Usano Toyoda、Akimitsu Okamoto
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] Evaluation of nucleosome structure alteration and accessibility change caused by platinum-based antineoplastics2022
- Author(s)
  Xuanyu LIAO、Takafumi Furuhata、Akimitsu Okamoto、Ikuma Arakaki
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] Indirect ubiquitination for targeted degradation of the transcription factor2022
- Author(s)
  Ryoka Fujita、Takafumi Furuhata、Yuto Matsumura、Tokiha Ozawa、Akimitsu Okamoto
- Organizer
  第４８回国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] ケモユビキチン：生物学と合成化学の融合がもたらす新発想の創薬の芽2022
- Author(s)
  古畑隆史、佐伯泰、岡本晃光
- Organizer
  第1回日本科学振興協会（JAAS）キックオフミーティング
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] ユビキチンキメラ分子による転写因子のケミカルノックダウン2022
- Author(s)
  吉田和生、藤田涼香、古畑隆史、岡本晃充
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PROJECT-21K19040
[Presentation] 固相合成に適したチオエステル前駆体システイニルプロリルイミドによるタンパク質化学合成2021
- Author(s)
  中津幸輝、梁瀬将史、林剛介、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] ニトロ基およびアゾ基の生体還元を利用したFloxuridineオリゴマーの低酸素活性化2021
- Author(s)
  森廣邦彦、石鍋拓郎、高津正子、大澤毅、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 細胞内タンパク質送達を指向した刺激溶解性タンパク質凝集体の開発2021
- Author(s)
  山本一穂、山口哲志、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 光化学インターナリゼーションに有効な近赤外光吸収色素の合成と評価2021
- Author(s)
  濵邉美佳子、出羽和花子、大橋瑠子、浜窪隆雄、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] 細胞膜裏側の定量的1細胞解析のための細胞膜シートアレイの開発2021
- Author(s)
  梅田侑生、山口哲志、山平真也、中村元直、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] 固相合成に適したチオエステル前駆体システイニルプロリルイミドによるタンパク質化学合成2021
- Author(s)
  中津幸輝、梁瀬将史、林剛介、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] 光化学インターナリゼーションに有効な近赤外光吸収色素の合成と評価2021
- Author(s)
  濵邉美佳子、出羽和花子、大橋瑠子、浜窪隆雄、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] ニトロ基およびアゾ基の生体還元を利用したFloxuridineオリゴマーの低酸素活性化2021
- Author(s)
  森廣邦彦、石鍋拓郎、高津正子、大澤毅、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] 細胞内タンパク質送達を指向した刺激溶解性タンパク質凝集体の開発2021
- Author(s)
  山本一穂、山口哲志、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] 固相合成に適したチオエステル前駆体システイニルプロリルイミドによるタンパク質化学合成2021
- Author(s)
  中津幸輝、梁瀬将史、林剛介、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] 生体分子の選択的可視化を実現する光活性化アルキンタグ2021
- Author(s)
  中村聖、山口哲志、小阪高広、中村元直、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] Ru触媒を用いたリンカーヒストンH1.2とHP1αの化学合成とその翻訳後修飾の機能解析2021
- Author(s)
  加茂直己、鯨井智也、胡桃坂仁志、村上裕、林剛介、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] 光誘起型伸長反応を用いたポリユビキチンの鎖長制御手法の確立2021
- Author(s)
  村山伊織、古畑隆史、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] Ru触媒を用いたリンカーヒストンH1.2とHP1αの化学合成とその翻訳後修飾の機能解析2021
- Author(s)
  加茂直己、鯨井智也、胡桃坂仁志、村上裕、林剛介、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] 光誘起型伸長反応を用いたポリユビキチンの鎖長制御手法の確立2021
- Author(s)
  村山伊織、古畑隆史、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] 光化学インターナリゼーションに有効な近赤外光吸収色素の合成と評価2021
- Author(s)
  濵邉美佳子、出羽和花子、大橋瑠子、浜窪隆雄、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 生体分子の選択的可視化を実現する光活性化アルキンタグ2021
- Author(s)
  中村聖、山口哲志、小阪高広、中村元直、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 細胞膜裏側の定量的1細胞解析のための細胞膜シートアレイの開発2021
- Author(s)
  梅田侑生、山口哲志、山平真也、中村元直、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 細胞内タンパク質送達を指向した刺激溶解性タンパク質凝集体の開発2021
- Author(s)
  山本一穂、山口哲志、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] ニトロ基およびアゾ基の生体還元を利用したFloxuridineオリゴマーの低酸素活性化2021
- Author(s)
  森廣邦彦、石鍋拓郎、高津正子、大澤毅、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] 細胞膜透過性を指向する含フッ素オリゴヌクレオチドの合成と評価2021
- Author(s)
  渡邉ほの香、相川光介、森廣邦彦、岡本晃充、岡添隆
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] 光誘起型伸長反応を用いたポリユビキチンの鎖長制御手法の確立2021
- Author(s)
  村山伊織、古畑隆史、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 細胞膜透過性を指向する含フッ素オリゴヌクレオチドの合成と評価2021
- Author(s)
  渡邉ほの香、相川光介、森廣邦彦、岡本晃充、岡添隆
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] 細胞膜裏側の定量的1細胞解析のための細胞膜シートアレイの開発2021
- Author(s)
  梅田侑生、山口哲志、山平真也、中村元直、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] Ru触媒を用いたリンカーヒストンH1.2とHP1αの化学合成とその翻訳後修飾の機能解析2021
- Author(s)
  加茂直己、鯨井智也、胡桃坂仁志、村上裕、林剛介、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 生体分子の選択的可視化を実現する光活性化アルキンタグ2021
- Author(s)
  中村聖、山口哲志、小阪高広、中村元直、岡本晃充
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] 細胞膜透過性を指向する含フッ素オリゴヌクレオチドの合成と評価2021
- Author(s)
  渡邉ほの香、相川光介、森廣邦彦、岡本晃充、岡添隆
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] Total chemical synthesis of linker histone H1.2 and heterochromatin protein 1 alpha through one-pot multiple peptide ligation using Ru catalyst2020
- Author(s)
  Naoki Kamo、Gosuke Hayashi、Tomoya Kujirai、Hitoshi Kurumizaka、Hiroshi Murakami、Akimitsu Okamoto
- Organizer
  第57回ペプチド討論会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 低酸素環境下で活性化するFluoxuridineオリゴマーの開発2020
- Author(s)
  森廣邦彦、石鍋拓郎、高津正子、岡本晃充
- Organizer
  第14回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 金属イオン曝露によるDNAメチル化レベル変化の蛍光解析2020
- Author(s)
  森廣邦彦、劉杉、竹内芙美香、岡本晃充
- Organizer
  第42回日本光医学・光生物学会
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] 低酸素環境下で活性化するFluoxuridineオリゴマーの開発2020
- Author(s)
  森廣邦彦、石鍋拓郎、高津正子、岡本晃充
- Organizer
  第14回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] 低酸素環境下で活性化するFluoxuridineオリゴマーの開発2020
- Author(s)
  森廣邦彦、石鍋拓郎、高津正子、岡本晃充
- Organizer
  第14回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] 金属イオン曝露によるDNAメチル化レベル変化の蛍光解析2020
- Author(s)
  森廣邦彦、劉杉、竹内芙美香、岡本晃充
- Organizer
  第42回日本光医学・光生物学会
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] The use of cysteinylprolyl imide peptide as an Fmoc-compatible crypto-thioester2020
- Author(s)
  Koki Nakatsu、Masafumi Yanase、Gosuke Hayashi、Akimitsu Okamoto
- Organizer
  第57回ペプチド討論会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] Total chemical synthesis of linker histone H1.2 and heterochromatin protein 1 alpha through one-pot multiple peptide ligation using Ru catalyst2020
- Author(s)
  Naoki Kamo、Gosuke Hayashi、Tomoya Kujirai、Hitoshi Kurumizaka、Hiroshi Murakami、Akimitsu Okamoto
- Organizer
  第57回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] Total chemical synthesis of linker histone H1.2 and heterochromatin protein 1 alpha through one-pot multiple peptide ligation using Ru catalyst2020
- Author(s)
  Naoki Kamo、Gosuke Hayashi、Tomoya Kujirai、Hitoshi Kurumizaka、Hiroshi Murakami、Akimitsu Okamoto
- Organizer
  第57回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] 金属イオン曝露によるDNAメチル化レベル変化の蛍光解析2020
- Author(s)
  森廣邦彦、劉杉、竹内芙美香、岡本晃充
- Organizer
  第42回日本光医学・光生物学会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] The use of cysteinylprolyl imide peptide as an Fmoc-compatible crypto-thioester2020
- Author(s)
  Koki Nakatsu、Masafumi Yanase、Gosuke Hayashi、Akimitsu Okamoto
- Organizer
  第57回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] The use of cysteinylprolyl imide peptide as an Fmoc-compatible crypto-thioester2020
- Author(s)
  Koki Nakatsu、Masafumi Yanase、Gosuke Hayashi、Akimitsu Okamoto
- Organizer
  第57回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] Inorganic reactions for analysis of epigenetically modified DNA2019
- Author(s)
  Akimitsu Okamoto
- Organizer
  19th International Conference on Biological Inorganic Chemistry (ICBIC-19)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 細胞内分子動態解析のための光活性化アルキンタグ2019
- Author(s)
  中村聖、山口哲志、小阪高広、岡本晃充
- Organizer
  2019年度生物工学若手研究者の集い（若手会）夏のセミナー
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] 感光性クリック試薬を用いた異種細胞位置制御技術の開発2019
- Author(s)
  小阪高広、山口哲志、泉田森、岡本晃充
- Organizer
  生体機能関連化学部会若手の会第31回サマースクール
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] Reaction design for highly efficient chemical protein synthesis2019
- Author(s)
  Gosuke Hayashi, Takuma Sueoka, Masafumi Yanase, Naoki Kamo, and Akimitsu Okamoto
- Organizer
  ACS Meeting 2019 Spring
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] タンパク質化学合成を指向したチオエステル前駆体CPI(Cysteinylprolyl imide) の設計と機能評価2019
- Author(s)
  中津幸輝、梁瀬将史、林剛介、岡本晃充
- Organizer
  生体機能関連化学部会若手の会第31回サマースクール
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] タンパク質化学合成を指向したチオエステル前駆体CPI(Cysteinylprolyl imide) の設計と機能評価2019
- Author(s)
  中津幸輝、梁瀬将史、林剛介、岡本晃充
- Organizer
  生体機能関連化学部会若手の会第31回サマースクール
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 感光性クリック試薬を用いた異種細胞位置制御技術の開発2019
- Author(s)
  小阪高広、山口哲志、泉田森、岡本晃充
- Organizer
  生体機能関連化学部会若手の会第31回サマースクール
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] 細胞運理を志向した光溶解性ゲル充填マイクロウェルアレイ2019
- Author(s)
  山口哲志、細金剛、大橋友紀、榊原昇一、田端和仁、野地博行、岡本晃充
- Organizer
  第13回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] 1細胞間相互作用解析のための光誘導型クリック反応表面2019
- Author(s)
  小阪高広、山口哲志、泉田森、岡本晃充
- Organizer
  第13回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] Inorganic reactions for analysis of epigenetically modified DNA2019
- Author(s)
  Akimitsu Okamoto
- Organizer
  19th International Conference on Biological Inorganic Chemistry (ICBIC-19)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] タンパク質化学合成を指向したチオエステル前駆体CPI(Cysteinylprolyl imide) の設計と機能評価2019
- Author(s)
  中津幸輝、梁瀬将史、林剛介、岡本晃充
- Organizer
  生体機能関連化学部会若手の会第31回サマースクール
- Invited
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] 1細胞間相互作用解析のための光誘導型クリック反応表面2019
- Author(s)
  小阪高広、山口哲志、泉田森、岡本晃充
- Organizer
  第13回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] 光反応性クリック試薬を用いた細胞間相互作用解析手法の開発2019
- Author(s)
  小阪高広、山口哲志、泉田森、岡本晃充
- Organizer
  第68回高分子討論会
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] ターンオン型蛍光プローブを用いたテロメラーゼ活性の生細胞内センシング2019
- Author(s)
  森廣邦彦、Jiazhuo Chen, 福井大介、Guo Lihao、岡本晃充
- Organizer
  第41回日本光医学・光生物学会
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] ターンオン型蛍光オリゴヌクレオチドプローブを用いたテロメラーゼ活性の生細胞内センシング2019
- Author(s)
  森廣邦彦、Chen Jiazhuo、福井大介、Guo Lihao、岡本晃充
- Organizer
  第13回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] 光反応性クリック試薬を用いた細胞間相互作用解析手法の開発2019
- Author(s)
  小阪高広、山口哲志、泉田森、岡本晃充
- Organizer
  第68回高分子討論会
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] ターンオン型蛍光オリゴヌクレオチドプローブを用いたテロメラーゼ活性の生細胞内センシング2019
- Author(s)
  森廣邦彦、Chen Jiazhuo、福井大介、Guo Lihao、岡本晃充
- Organizer
  第13回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] Chemical Reactions for Analysis of Epigenetically Modified DNA2019
- Author(s)
  Akimitsu Okamoto
- Organizer
  Epigenetics & Bioengineering Coference (EpiBio 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] Photo-responsive cell immobilization reagents for cell manipulation on solid phase2019
- Author(s)
  Satoshi Yamaguchi, Shin Izuta, Shinya Yamahara, Teruyuki Nagamune, Akimitsu Okamoto
- Organizer
  The 18th Asian Pacific Confederation of Chemical Engineering Congress (APCChE2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 細胞内分子動態解析のための光活性化アルキンタグ2019
- Author(s)
  中村聖、山口哲志、小阪高広、岡本晃充
- Organizer
  2019年度生物工学若手研究者の集い（若手会）夏のセミナー
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 細胞運理を志向した光溶解性ゲル充填マイクロウェルアレイ2019
- Author(s)
  山口哲志、細金剛、大橋友紀、榊原昇一、田端和仁、野地博行、岡本晃充
- Organizer
  第13回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] Chemical Reactions for Analysis of Epigenetically Modified DNA2019
- Author(s)
  Akimitsu Okamoto
- Organizer
  Epigenetics & Bioengineering Coference (EpiBio 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] 細胞内分子動態解析のための光活性化アルキンタグ2019
- Author(s)
  中村聖、山口哲志、小阪高広、岡本晃充
- Organizer
  2019年度生物工学若手研究者の集い（若手会）夏のセミナー
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] Live-Cell Sensing of Telomerase Activity2019
- Author(s)
  Akimitsu Okamoto, Kunihiko Morihiro, Jiazhuo Chen, Daisuke Fukui and Lihao Guo
- Organizer
  Asia 3 Roundtable of Nucleic Acid 2019 (A3RONA)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] ターンオン型蛍光オリゴヌクレオチドプローブを用いたテロメラーゼ活性の生細胞内センシング2019
- Author(s)
  森廣邦彦、Chen Jiazhuo、福井大介、Guo Lihao、岡本晃充
- Organizer
  第13回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] 感光性クリック試薬を用いた異種細胞位置制御技術の開発2019
- Author(s)
  小阪高広、山口哲志、泉田森、岡本晃充
- Organizer
  生体機能関連化学部会若手の会第31回サマースクール
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] 光反応性クリック試薬を用いた細胞間相互作用解析手法の開発2019
- Author(s)
  小阪高広、山口哲志、泉田森、岡本晃充
- Organizer
  第68回高分子討論会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] Live-Cell Sensing of Telomerase Activity2019
- Author(s)
  Akimitsu Okamoto, Kunihiko Morihiro, Jiazhuo Chen, Daisuke Fukui and Lihao Guo
- Organizer
  Asia 3 Roundtable of Nucleic Acid 2019 (A3RONA)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] タンパク質化学合成を指向したチオエステル前駆体CPI(Cysteinylprolyl imide) の設計と機能評価2019
- Author(s)
  中津幸輝、梁瀬将史、林剛介、岡本晃充
- Organizer
  生体機能関連化学部会若手の会第31回サマースクール
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] Photo-responsive cell immobilization reagents for cell manipulation on solid phase2019
- Author(s)
  Satoshi Yamaguchi, Shin Izuta, Shinya Yamahara, Teruyuki Nagamune, Akimitsu Okamoto
- Organizer
  The 18th Asian Pacific Confederation of Chemical Engineering Congress (APCChE2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22245
[Presentation] ターンオン型蛍光プローブを用いたテロメラーゼ活性の生細胞内センシング2019
- Author(s)
  森廣邦彦、Jiazhuo Chen, 福井大介、Guo Lihao、岡本晃充
- Organizer
  第41回日本光医学・光生物学会
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] Photo-responsive cell immobilization reagents for cell manipulation on solid phase2019
- Author(s)
  Satoshi Yamaguchi, Shin Izuta, Shinya Yamahara, Teruyuki Nagamune, Akimitsu Okamoto
- Organizer
  The 18th Asian Pacific Confederation of Chemical Engineering Congress (APCChE2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] Live-Cell Sensing of Telomerase Activity2019
- Author(s)
  Akimitsu Okamoto, Kunihiko Morihiro, Jiazhuo Chen, Daisuke Fukui and Lihao Guo
- Organizer
  Asia 3 Roundtable of Nucleic Acid 2019 (A3RONA)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] 細胞運理を志向した光溶解性ゲル充填マイクロウェルアレイ2019
- Author(s)
  山口哲志、細金剛、大橋友紀、榊原昇一、田端和仁、野地博行、岡本晃充
- Organizer
  第13回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] ターンオン型蛍光プローブを用いたテロメラーゼ活性の生細胞内センシング2019
- Author(s)
  森廣邦彦、Jiazhuo Chen, 福井大介、Guo Lihao、岡本晃充
- Organizer
  第41回日本光医学・光生物学会
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] 1細胞間相互作用解析のための光誘導型クリック反応表面2019
- Author(s)
  小阪高広、山口哲志、泉田森、岡本晃充
- Organizer
  第13回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] Inorganic reactions for analysis of epigenetically modified DNA2019
- Author(s)
  Akimitsu Okamoto
- Organizer
  19th International Conference on Biological Inorganic Chemistry (ICBIC-19)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] Chemical Reactions for Analysis of Epigenetically Modified DNA2019
- Author(s)
  Akimitsu Okamoto
- Organizer
  Epigenetics & Bioengineering Coference (EpiBio 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05504
[Presentation] EXCITON-CONTROLLED FLUORESCENT NUCLEIC ACIDS FOR BIOIMAGING2018
- Author(s)
  Lihao Guo, Akimitsu Okamoto
- Organizer
  PhotoIUPAC2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03931
[Presentation] ヒドロキシアパタイトを用いた新規触媒反応の開発2018
- Author(s)
  宇佐美花穂、岡本晃充
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PUBLICLY-17H05227
[Presentation] タンパク質化学合成を利用したヒストンH2A-H2B研究への展開2017
- Author(s)
  末岡拓馬、林剛介、榊原大輔、岡本晃充
- Organizer
  日本ケミカルバイオロジー学会　第12回年会
- Data Source
  KAKENHI-PROJECT-15H02190
[Presentation] Bacterial population quantification in solid state fermentation by exciton-controlled fluorescent neomycin-competition RNA aptamer2017
- Author(s)
  L. Guo and A. Okamoto
- Organizer
  the 18th Tetrahedron Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KT0057
[Presentation] アリル保護基を用いたAsp-Cys間のNCL連結法の開発2017
- Author(s)
  加茂直己、林剛介、岡本晃充
- Organizer
  第11回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-15H02190
[Presentation] Silyl-protected Alkynes for Multiple Labeling of Chemically Synthesized Protein2017
- Author(s)
  G. Hayashi, N. Kamo and A. Okamoto
- Organizer
  25th American Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02190
[Presentation] リボヌクレオシドの前生物的合成経路の探求2017
- Author(s)
  宇佐美　花穂・岡本　晃充
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  横浜
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PUBLICLY-15H01058
[Presentation] Chemical approach to nucleic acid diversity2017
- Author(s)
  Akimitsu Okamoto
- Organizer
  JSPS-NRCT 2017 and IAMPS 33
- Place of Presentation
  タイ・バンコク
- Year and Date
  2017-03-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02190
[Presentation] 化学合成ヒストンを用いたエピジェネティクス解析プラットフォームの構築2017
- Author(s)
  林剛介、末岡拓馬、坂元亮介、榊原大輔、石橋真帆、岡本晃充
- Organizer
  日本ケミカルバイオロジー学会　第12回年会
- Data Source
  KAKENHI-PROJECT-15H02190
[Presentation] Evaluation of Histone H2A-H2B Dimer based on Protein Chemical Synthesis2017
- Author(s)
  Takuma Sueoka, Gosuke Hayashi, Daisuke Sakakibara and Akimitsu Okamoto
- Organizer
  25th American Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02190
[Presentation] ヌクレオソーム動態解析を指向した化学合成ヒストンタンパク質2017
- Author(s)
  林剛介、末岡拓馬、岡本晃充
- Organizer
  第55回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-15H02190
[Presentation] ヒドロキシアパタイトによって触媒される糖の合成2017
- Author(s)
  宇佐美花穂、岡本晃充
- Organizer
  日本化学会秋季事業　第7回CSJ化学フェスタ2017
- Data Source
  KAKENHI-PUBLICLY-17H05227
[Presentation] 鉱物によって触媒される糖の部分合成2016
- Author(s)
  宇佐美花穂、岡本晃充
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  京都
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PUBLICLY-15H01058
[Presentation] 5-Hydroxymethylcytosine-Specific Oxidation: DNA -Friendly Cu(II)/TEMPO-Catalyzed Oxidation and Apprications2016
- Author(s)
  Akimitsu Okamoto
- Organizer
  The 22th International Round Table on Nucleosides, Nucleotides and Nucleic Acids (XXII IRT)
- Place of Presentation
  フランス・パリ
- Year and Date
  2016-07-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02190
[Presentation] ポリADP リボースの化学合成2016
- Author(s)
  林恭平、岡本晃充
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  京都
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-15K13736
[Presentation] Modified ECHO Probes for Effective Intracellular RNA Imaging2013
- Author(s)
  Akimitsu Okamoto, Kaori Sugizaki, Takuma Sueoka, Katsuya Takeda, Gosuke Hayashi, Shuji Ikeda, Mizue Yuki and Dan Ohtan Wang
- Organizer
  The 40th International Symousium on Nucleic Acid Chemistry 2013 (ISNAC2013)
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2013-11-13
- Data Source
  KAKENHI-PROJECT-13F03342
[Presentation] Live-cell Imaging of Endogenous RNA with Exciton-controlled Hybridization-sensitive Fluorescent Probes2013
- Author(s)
  Ikumi Oomoto, Asuka Hirano, Hiroki Umeshima, Mineko Kengaku, Akimitsu Okamoto, Tomomi Shimogori, Dan Ohtan Wang
- Organizer
  15th annual meeting of RNA society
- Data Source
  KAKENHI-PROJECT-24650216
[Presentation] Tungsten reacting with 5-hydroxymethylcytosine2013
- Author(s)
  Akimitsu Okamoto
- Organizer
  Epigenomics of Common Diseases 2013
- Place of Presentation
  Hinxton, UK
- Year and Date
  2013-11-07
- Data Source
  KAKENHI-PROJECT-13F03342
[Presentation] 核酸プローブを駆使した生体内RNA時空間制御の蛍光イメージング2013
- Author(s)
  王丹・平野明日香・大本育美・梅島宏樹・見学美根子・下郡智美・岡本晃充
- Organizer
  日本化学会第93回春季年会
- Data Source
  KAKENHI-PROJECT-24650216
[Presentation] ECHOプローブによる細胞内RNAイメージング2012
- Author(s)
  林剛介、池田修司、王丹、杉崎香織、末岡拓馬、岡本晃充
- Organizer
  第6回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-24650216
[Presentation] Live-cell RNA imaging through advanced ECHO probes2012
- Author(s)
  岡本晃充
- Organizer
  第39回国際核酸化学シンポジウム
- Data Source
  KAKENHI-PROJECT-24650216
[Presentation] Hybridization-Sensitive Fluorescent Nucleic Acids for Effective RNA Imaging2010
- Author(s)
  Shuji Ikeda, Takeshi Kubota, Akimitsu Okamoto
- Organizer
  Challenges in Organic Chemistry and Chemical Biology (ISACS1)
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] Fluorescent Nucleotides for Efficient Nucleic Acid Sensin2010
- Author(s)
  Akimitsu Okamoto
- Organizer
  11th International Chemistry Conference and Exhibition in Africa (11 ICCA)
- Place of Presentation
  Luxor, Egypt(Invited)
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] Application of artificial DNA probes in genome-scale DNA methylation analysis and evaluation of nucleic acid functions2010
- Author(s)
  Akimitsu Okamoto
- Organizer
  BIG-CAS Seminar
- Place of Presentation
  Beijing, China(Invited)
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] Fluorescent Nucleotides for Efficient Nucleic Acid Sensing2010
- Author(s)
  Okamoto, A.
- Organizer
  11th International Chemistry Conference and Exhibition in Africa (11 ICCA)
- Place of Presentation
  Luxor, Egypt(Invited)
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] Exciton-controlled Hybridization-sensitive Fluorescent Oligonucleotides2010
- Author(s)
  Takeshi Kubota, Shuji Ikeda, Hiroyuki Yanagisawa, Mizue Yuki, Kaori Sugizaki, Akimitsu Okamoto
- Organizer
  29th International Round Table on Nucleosides, Nucleotides and Nucleic Acids (IRT 2010)
- Place of Presentation
  Lyon, France
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] Hybridization-Sensitive Fluorescent Nucleic Acids for Live Cell RNA Imaging2010
- Author(s)
  Akimitsu Okamoto
- Organizer
  2nd Workshop on Fluorescence Chemosensor and Bio-imaging
- Place of Presentation
  Dalian, China(Invited)
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] Thiazole Orange Dimer on a Nucleotide : Application to Live Cell RNA Imaging2010
- Author(s)
  Akimitsu Okamoto, Shuji Ikeda, Takeshi Kubota
- Organizer
  23th IUPAC Symposium on Photochemistry
- Place of Presentation
  Ferrara, Italy
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] Artificial Zinc Finger Peptide for Recognition of Methylated DNA Duplex2010
- Author(s)
  Akiko Nomura, Akimitsu Okamoto
- Organizer
  The 5th Asian Biological Inorganic Chemistry Conference
- Place of Presentation
  Kaohsiung, Taiwan
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] Photochemical design for live cell RNA imaging2010
- Author(s)
  Akimitsu Okamoto
- Organizer
  International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
- Place of Presentation
  Honolulu, USA(Invited)
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] A short talk on ICON and ECHO probes2010
- Author(s)
  Akimitsu Okamoto
- Organizer
  Asian 3 Roundtable on Nucleic Acids (A3RONA 2010 JAPAN)
- Place of Presentation
  Osaka, Japan(Invited)
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] DNA-osmium complex : Pinpoint detection of methylated cytosines2010
- Author(s)
  Akimitsu Okamoto
- Organizer
  International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
- Place of Presentation
  Honolulu, USA(Invited)
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] Addition of Osmium to DNA Pyrimidine Bases2009
- Author(s)
  岡本晃充
- Organizer
  1 4th International Conference on Biological Inorganic Chemistry (ICBIC 14)
- Place of Presentation
  Nagoya Congress Center, Nagoya
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-20014030
[Presentation] Exciton-controlled probes for live cell RNA imaging2009
- Author(s)
  Akimitsu Okamoto
- Organizer
  42nd IUPAC Congress
- Place of Presentation
  Glasgow, UK(Invited)
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] ICON Probe : Osmium Complexation for Pinpoint Detection of Methylated Cytosines2009
- Author(s)
  Akimitsu Okamoto
- Organizer
  BIT Life Sciences' 2nd Annual Congress and Expo of Molecular Diagnostics (CEMD-2009)
- Place of Presentation
  Beijing, China(Invited)
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] Excitonic interaction: New photochemical control for nucleic acid imaging2009
- Author(s)
  岡本晃充
- Organizer
  i CeMS Biomaterials at the interface of chemistry, physics, and biology
- Place of Presentation
  Kyoto University Clock Tower Centennial Hall, Kyoto
- Year and Date
  2009-07-27
- Data Source
  KAKENHI-PROJECT-20014030
[Presentation] Addition of Osmium to DNA Pyrimidine Bases2009
- Author(s)
  岡本晃充
- Organizer
  14th International Conference on Biological Inorganic Chemistry(ICBIC 14)
- Place of Presentation
  Nagoya Congress Center, Nagoya
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-20014030
[Presentation] Doubly Dye-Labeled Nucleotide : Toward Efficient RNA Imaging2009
- Author(s)
  Akimitsu Okamoto
- Organizer
  The 13th Asian Chemical Congress
- Place of Presentation
  Shanghai, China(Invited)
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] ICON probe: Osmium complexation for pinpoint detection of methylated cytosines2009
- Author(s)
  岡本晃充
- Organizer
  B IT 2nd Annual Congress and Expo of Molecular Diagnostics (CEMD-2009)
- Place of Presentation
  Beijing International Convention Center, China
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-20014030
[Presentation] Addition of Osmium to DNA Pyrimidine Bases2009
- Author(s)
  Akimitsu Okamoto
- Organizer
  14th International Conference on Biological Inorganic Chemistry
- Place of Presentation
  Nagoya, Japan(Invited)
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] Addition of Osmium to DNA Pyrimidine Bases2009
- Author(s)
  岡本晃充
- Organizer
  14th International Conference on Biological Inorganic Chemistry(ICBIC 14)
- Place of Presentation
  Nagoya Congress Center, Nagoya
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-20655039
[Presentation] Exciton-controlled fluorescence : Application to hybridization-sensitive fluorescent DNA probe2009
- Author(s)
  Akimitsu Okamoto, Shuji Ikeda, Takeshi Kubota, Mizue Yuki, Hiroyuki Yanagisawa
- Organizer
  The 6th International symposium on Nucleic Acid Chemistry (61SNAC2009)
- Place of Presentation
  Takayama, Japan
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] Addition of Osmium to DNA Pyrimidine Bases2009
- Author(s)
  岡本晃充
- Organizer
  14th International Conference on Biological Inorganic Chemistry(ICBIC 14)
- Place of Presentation
  Nagoya Congress Center, Nagoya
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] Exciton-controlled probes for live cell RNA imaging2009
- Author(s)
  岡本晃充
- Organizer
  4 2nd IUPAC Congress "Chemistry for Solving Biological Problems"
- Place of Presentation
  The Scottish Exhibition and Conference Centre, Glasgow, UK
- Year and Date
  2009-08-06
- Data Source
  KAKENHI-PROJECT-20014030
[Presentation] 細胞内RNAの可視化技術2009
- Author(s)
  岡本晃充
- Organizer
  私立大学戦略的研究基盤形成支援事業「細胞光計測・制御のための新規バイオ技術形成クラスター」講演会
- Place of Presentation
  慶應義塾大学
- Year and Date
  2009-02-25
- Data Source
  KAKENHI-PROJECT-20014030
[Presentation] Doubly Dye-Labeled Nucleotide: Toward Efficient RNA Imaging2009
- Author(s)
  岡本晃充
- Organizer
  T he 13th Asian Chemical Congress
- Place of Presentation
  Shanghai International Convention Center, China
- Year and Date
  2009-09-14
- Data Source
  KAKENHI-PROJECT-20014030
[Presentation] Photochemical Probe Design for Multicolor RNA Imaging in Living Cells2009
- Author(s)
  Takeshi Kubota, Shuji Ikeda, Akimitsu Okamoto
- Organizer
  11th International Kyoto Conference on New Aspects of Organic Chemistry (IKCOC-11)
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] メチル化したDNAを高効率検出する新しい化学2009
- Author(s)
  岡本晃充
- Organizer
  大阪大学蛋白質研究所セミナー「疾患の基盤としてのエピジェネティクス」
- Place of Presentation
  大阪大学蛋白質研究所
- Year and Date
  2009-06-29
- Data Source
  KAKENHI-PROJECT-20014030
[Presentation] Doubly Dye-Labeled Nucleotide: Synthesis, Photochemistry, and Application to RNA Imaging2009
- Author(s)
  Akimitsu Okamoto, Shuji Ikeda, Mizue Yuki, Takeshi Kubota
- Organizer
  Tenth Tetrahedron Symposium
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] Excitonic Interaction : New Photochemical Control for Nucleic Acid Imaging2009
- Author(s)
  Akimitsu Okamoto
- Organizer
  The Fifth iCeMS International Symposium
- Place of Presentation
  Kyoto, Japan(Invited)
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] Doubly Thiazole Orange-Labeled Nucleotide: Application to Hybridization-Sensitive DNA Probe2008
- Author(s)
  岡本晃充
- Organizer
  2 008 Korea-Japan Symposium on Frontier Photoscience (KJFP 2008)
- Place of Presentation
  Ramada Hotel in Jeju Island, Korea
- Year and Date
  2008-09-26
- Data Source
  KAKENHI-PROJECT-20014030
[Presentation] Intracellular mRNA imaging with a hybridization sensitive fluorescent nucleotide2008
- Author(s)
  Takeshi Kubota, Shuji Ikeda, Akimitsu Okamoto
- Organizer
  joint Symposium of 18th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids and 35th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] DNA-Osmium Complex for DNA Methylation Analysis2008
- Author(s)
  岡本晃充
- Organizer
  3 1st National Medicinal Chemistry Symposium
- Place of Presentation
  University of Pittsburgh
- Year and Date
  2008-06-18
- Data Source
  KAKENHI-PROJECT-20014030
[Presentation] Synthesis of bipyridine-adenine conjugates for DNA methylation analysis2008
- Author(s)
  Kazuki Tainaka, Akimitsu Okamoto
- Organizer
  14th Symposium on Chemistry of Nucleic Acid Components
- Place of Presentation
  Cesky Krumlov, Czech
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] DNA-Osmium Complex for DNA Methylation Analysis2008
- Author(s)
  岡本晃充
- Organizer
  31st National Medicinal Chemistry Symposium
- Place of Presentation
  University of Pittsburgh
- Year and Date
  2008-06-18
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] DNA-Osmium Complex for DNA Methylation Analysis2008
- Author(s)
  Akimitsu Okamoto
- Organizer
  31st National Medicinal Chemistry Symposium, American Chemical Society
- Place of Presentation
  Pittsburgh, USA(Invited)
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] Design of a fluorescent probe for DNA/RNA imaging2008
- Author(s)
  Akimitsu Okamoto, Takeshi Kubota, Shuji Ikeda
- Organizer
  joint Symposium of 18th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids and 35th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] DNA-Osmium Complex for DNA Methylation Analysis2008
- Author(s)
  岡本晃充
- Organizer
  31st National Medicinal Chemistry Symposium
- Place of Presentation
  University of Pittsburgh
- Year and Date
  2008-06-18
- Data Source
  KAKENHI-PROJECT-20655039
[Presentation] 化学設計DNAによる核酸簡易解析の一例2008
- Author(s)
  岡本晃充
- Organizer
  先端生命コロキウム2008
- Place of Presentation
  東京大学
- Year and Date
  2008-11-12
- Data Source
  KAKENHI-PROJECT-20014030
[Presentation] Doubly Thiazole Orange-Labeled Nucleotide Application to Hybridization-Sensitive DNA Probe2008
- Author(s)
  Takeshi Kubota, Shuji Ikeda, Akimitsu Okamoto
- Organizer
  2008 Korea-Japan Symposium on Frontier Photoscience (KJFP 2008)
- Place of Presentation
  Jeju, Korea(Invited)
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] Reactivity of Thymine Doublet in Single Strand DNA with Osmium Reagent2008
- Author(s)
  Akiko Nomura, Akimitsu Okamoto
- Organizer
  joint Symposium of 18th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids and 35th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] DNA-Osmium Complex for DNA Methylation Analysis2008
- Author(s)
  岡本晃充
- Organizer
  31st National Medicinal Chemistry Symposium
- Place of Presentation
  University of Pittsburgh
- Year and Date
  2008-06-18
- Data Source
  KAKENHI-PROJECT-20014030
[Presentation] Control of DNA binding by a zinc finger peptide having and azobenzene photo-switch2008
- Author(s)
  Akiko Nomura, Akimitsu Okamoto
- Organizer
  4th Asian Biological Inorganic Chemistry Conference
- Place of Presentation
  Jeju, Korea
- Data Source
  KAKENHI-PROJECT-20350083
[Presentation] 周辺環境の微視的な誘電率変化をモニターする蛍光性核酸の設計2007
- Author(s)
  岡本晃充
- Organizer
  第29回日本光医学・光生物学会
- Place of Presentation
  富山国際会議場
- Year and Date
  2007-07-13
- Data Source
  KAKENHI-PROJECT-18014012
[Presentation] DNA修飾検出に対するいくつかの化学的アプローチ
- Author(s)
  岡本晃充
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-26620129
[Presentation] Chemical Epigenetics: Chemical Visualization of Methylated DNA and Expressed RNA
- Author(s)
  Akimitsu Okamoto
- Organizer
  ConTech2014 RCAST-AICT Joint Symposium
- Place of Presentation
  Suwon, Korea
- Year and Date
  2014-11-28 – 2014-11-29
- Invited
- Data Source
  KAKENHI-PROJECT-26620129
[Presentation] Diazirine Photocrosslinking Recruits Activated FTO Demethylase Complexes for Specific N6-methyladenosine Recognition
- Author(s)
  JEONG, Hyun Seok; OKAMOTO, Akimitsu
- Organizer
  日本化学会第95春季年会
- Place of Presentation
  千葉
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-13F03342

1. Abe Takahiro (20383250)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
2. 阿部雅修 (10392333)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 小松紀子 (10644106)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
4. JEONG Hyun Seok

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
5. LEZHAVA Alexander (40443048)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. WANG Dan Ohtan (50615482)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. SUGI Takuma (70571305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. SANDO SHINSUKE (20346084)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SAITO Isao (20026082)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Watanabe Yuichiro (60183125)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Sato Masanao (20517693)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SAEKI Yasushi (80462779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. Yamaguchi Satoshi (80398106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 藤本健造 (90293894)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 林剛介 (40648268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. 濱田隆宏 (20452534)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 内藤幹彦 (00198011)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 村田茂穂 (20344070)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 岩井一宏 (60252459)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 深井周也 (10361792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 出水庸介 (90389180)

# of Collaborated Projects: 1 results

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22. 太期健二 (20466866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 浜窪隆雄 (90198797)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
24. 大橋瑠子 (20447600)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 森廣邦彦 (70713890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
26. 沖昌也 (60420626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 伊藤由美 (00176372)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 高才東 (00911299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
29. 沢井奈津子 (10403031)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. HAYASHI Yasunori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. YAMAHIRA Shinya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 油谷浩幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 永江玄太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 田中啓二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 池内与志穂

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 鈴木穣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 福田良一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okamoto Akimitsu 岡本 晃充

OKAMOTO Akimitsu 岡本 晃充

岡本 晃光 オカモト アキミツ

Research Projects

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Epigenomic Chemical Transformations Caused by Nucleic Acid Molecular ReprogrammingPrincipal Investigator

Principal Investigator

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Unprecedented and potent immunoregulation provided by protein capture with functionalized small synthetic nucleic acidsPrincipal Investigator

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Analysis of the mechanism by which nucleic acid assemblies exhibit anticancer activityPrincipal Investigator

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Exploration of the modification of genomic higher-order structures in the cell nucleus by aggregation of chemically synthesized short nucleic acidsPrincipal Investigator

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Synthesis and function analysis of mini-chromosome modelPrincipal Investigator

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Chemical synthesis of ubiquitin codesPrincipal Investigator

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Single cell mapping of epigenetic modifications through super-nucleosome constructionPrincipal Investigator

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Nucleoside synthesis: Apatite phosphate catalytic reaction from glycolaldehydePrincipal Investigator

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Development of nucleic acid enzymes for new nucleic acid medicines based on the transition state in molecular degradationPrincipal Investigator

Okamoto Akimitsu 岡本晃充

OKAMOTO Akimitsu 岡本晃充

岡本晃光オカモトアキミツ