YANO Masato 矢野正人

… Alternative Names

矢野正人ヤノマサト

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Researcher Number	60315299
Other IDs
Affiliation (Current)	2025: 熊本保健科学大学, 保健科学部, 教授
Affiliation (based on the past Project Information) *help	2016 – 2017: 熊本保健科学大学, 保健科学部, 教授 2013 – 2015: 熊本保健科学大学, 保健科学部, 准教授 2011 – 2012: 熊本大学, 大学院生命科学研究部, 助教 2009 – 2010: Kumamoto University, 大学院・生命科学研究部, 助教 2006 – 2008: Kumamoto University, Dept. Mol. Genet., Grad. Sch. Med. Sci., Assistant Professor … More 2005 – 2006: 熊本大学, 大学院医学薬学研究部, 助手 2003 – 2004: 熊本大学, 大学院・医学薬学研究部, 助手 2000 – 2002: Kumamoto University, School of Medicine, Assistant Professor, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator General medical chemistry / Cell biology Except Principal Investigator Biological Sciences / General medical chemistry
Keywords	Principal Investigator ミトコンドリア / 酸化ストレス / セラミド / タンパク質輸送 / ストレス応答 / TMEM65 / ABCB10 / 電子伝達系 / スフィンゴミエリン / スフィンゴ脂質 … More / シグナル伝達 / Bcl-2 / 膜タンパク質 / アポトーシス / AIP / Tom20 / トランスポーター / ストレス / ブルーネイティブゲル電気泳動 / リポタンパク質リパーゼ / 呼吸鎖複合体 / 脂肪萎縮 / ミトコンドリアストレス応答 / スフィンゴミエリン合成酵素 / スフィゴミエリン / 膵β細胞 / 活性酸素種 / インスリン / 脂質 / Bax / 膜 / 構造変化 / BH3-onlyタンパク質 / 活性制御 / 小胞体 / シトクロムc / SAM複合体 / 透過孔 / TPRモチーフ / シャペロン / プレ配列 / 蛍光タンパク質 / トラフィック / 外膜 / TOM / Hsp90 / two-hybrid / Tom22 / 膜透過 … More Except Principal Investigator Bim / t-Bid / Bcl-2 / CHOP / Omi / mitochondria / Tom22 / Tom20 / 分子シャペロン / ミトコンドリア / apoptosis / ER stress / 糖尿病 / ノックアウトマウス / Bax / 神経細胞死 / Akiraマウス / 一酸化窒素 / LPS / アンドロジェン受容体 / 精子形成 / XBP-1 / カスパーゼ / 熱耐性 / Hsp40 / Hsp70 / アポトーシス / 小胞体ストレス / molecular chaperon / translocation / preprotein / precequence / GFP / 前駆体タンパク質 / タンパク質輸送 / インポートレセプター / Tom34 / 膜透過 / 前駆体 / プレ配列 Less

Analysis of mitochondrial stress signaling pathwayPrincipal Investigator
- Principal Investigator
  
  Masato Yano
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kumamoto Health Science University
Analysis in the regulation mechanism of oxidative stress by sphingolipidPrincipal Investigator
- Principal Investigator
  
  YANO Masato
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kumamoto Health Science University
  Kumamoto University
Regulation of insulin secretion by sphingolipidsPrincipal Investigator
- Principal Investigator
  
  YANO Masato
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kumamoto University
Analysis on activity regulation of Bcl-2 in mitochondria and ERPrincipal Investigator
- Principal Investigator
  
  YANO Masato
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kumamoto University
ミトコンドリア外膜タンパク質輪送装置のアポトーシスにおける機能の解析Principal Investigator
- Principal Investigator
  
  矢野正人
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kumamoto University
ミトコンドリアタンパク質の外膜透過装置はアポトーシスに関与するか?Principal Investigator
- Principal Investigator
  
  矢野正人
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Kumamoto University
Functional analysis of chaperones in mammals
- Principal Investigator
  
  TERADA Kazutoyo, 森正敬
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
ミトコンドリアタンパク質の輸送とミトコンドリア形態形成の解析Principal Investigator
- Principal Investigator
  
  矢野正人
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Cell biology
- Research Institution
  Kumamoto University
Studies of mitochondrial protein import factors in mammals
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  General medical chemistry
- Research Institution
  Kumamoto University

All 2017 2016 2014 2013 2012 2011 2010 2009 2008 2007 2004

All Journal Article Presentation

[Journal Article] ABCB10 depletion reduces unfolded protein response in mitochondria.2017
- Author(s)
  Masato Yano
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 486 Issue: 2 Pages: 465-469
- DOI
  10.1016/j.bbrc.2017.03.063
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460378
[Journal Article] Mitochondrial inner and outer membrane separation in HeLa cells2014
- Author(s)
  Naotaka Nishimura, Masato Yano
- Journal Title
  
  bio-protocol
  
  Volume: 4 Pages: 1-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460378
[Journal Article] TMEM65 is a mitochondrial inner-membrane protein.2014
- Author(s)
  Naotaka Nishimura, Tomomi Gotoh, Yuichi Oike, Masato Yano
- Journal Title
  
  PeerJ
  
  Volume: 2 Pages: e349-e349
- DOI
  10.7717/peerj.349
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23590340, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26670405
[Journal Article] Increased oxidative stress impairs adipose tissue function in sphingomyelin synthase 1 null mice2013
- Author(s)
  Masato Yano, Tadashi Yamamoto, Naotaka Nishimura, Tomomi Gotoh, Ken Watanabe, Kazutaka Ikeda, Yohei Garan, Ryo Taguchi, Koichi Node, Toshiro Okazaki, Yuichi Oike
- Journal Title
  
  PLOS ONE
  
  Volume: 8 Issue: 4 Pages: 1-12
- DOI
  10.1371/journal.pone.0061380
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590340
[Journal Article] Mitochondrial Dysfunction and Increased Reactive Oxygen Species Impair Insulin Secretion in Sphingomyelin Synthase 1-null Mice.2011
- Author(s)
  Masato Yano, Ken Watanabe, Tadashi Yamamoto, Kazutaka Ikeda, Takafumi Senokuchi, Meihong Lu, Tsuyoshi Kadomatsu, Hiroto Tsukano, Masahito Ikawa, Masaru Okabe, Shohei Yamaoka, Toshiro Okazaki, Hisanori Umehara, Tomomi Gotoh, Wen-Jie Song, Koichi Node, Ryo Taguchi, Kazuya Yamagata, Yuichi Oike.
- Journal Title
  
  The Journal of Biological Chemistry 286
  
  Pages: 3992-4002
- NAID
  120006957387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790286
[Journal Article] Mitochondrial Dysfunction and Increased Reactive Oxygen Species Impair Insulin Secretion in Sphingomyelin Synthase 1-null Mice2011
- Author(s)
  Yano, et al.
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 286 Pages: 3992-4002
- NAID
  120006957387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790286
[Journal Article] The Endoplasmic Reticulum Stress-C/EBP Homologous Protein Pathway-Mediated Apoptosis in Macrophages Contributes to the Instability of Atherosclerotic Plaques.2010
- Author(s)
  Hiroto Tsukano, Tomomi Gotoh, Motoyoshi Endo, Keishi Miyata, Hirokazu Tazume, Tsuyoshi Kadomatsu, Masato Yano, Takao Iwawaki, Kenji Kohno, Kimi Araki, Hiroshi Mizuta, Yuichi Oike.
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology 30
  
  Pages: 1925-1932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790286
[Journal Article] Angiopoietin-Related Growth Factor Enhances Blood Flow Via Activation of the ERK1/2-eNOS-NO Pathway in a Mouse Hind-Limb Ischemia Model2008
- Author(s)
  Urano, T., Ito, Y., Akao, M., Sawa, T., Miyata, K., Tabata, M., Morisada, T., Hato, T., Yano, M., Kadomatsu, T., Yasunaga, K., Shibata, R., Murohara, T., Akaike, T., Tanihara, H., Suda, T., Oike, Y.
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology 28
  
  Pages: 827-834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790215
[Journal Article] In vitro analysis of Bc1-2 proteins inmitochondria and endoplasmic reticulum : Similarities in anti-apoptotic functions and differences in regulation.2007
- Author(s)
  M. Yano. K. Terada. T. Gotoh. & M. Mori
- Journal Title
  
  Exp. CellRes. 313(17)
  
  Pages: 3767-3778
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037257
[Journal Article] In vitro analysis of Bc1-2 proteins in mitochondria and endoplasmic reticulum: Similarities in anti-apoptotic functions and differences in regulation2007
- Author(s)
  Yano M., et. al.
- Journal Title
  
  Experimental Cell Research 313・17
  
  Pages: 3767-3778
- Data Source
  KAKENHI-PROJECT-17790195
[Journal Article] In vitro analysis of Bcl-2 proteins in mitochondria and endoplasmic reticulum: similarities in anti-apoptotic functions and differences in regulation.2007
- Author(s)
  Yano M., et. al.
- Journal Title
  
  Experimental Cell Research 313(17)
  
  Pages: 3767-3778
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790215
[Journal Article] In vitro analysis of Bcl-2 proteins in mitochondria and endoplasmic reticulum: Similarities in anti-apoptotic functions and differences in regulation2007
- Author(s)
  Yano, M., Terada, K., Gotoh, T., Mori, M.
- Journal Title
  
  Experimental Cell Research 313
  
  Pages: 3767-3778
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790215
[Journal Article] In vitro analysis of Bcl-2 proteins in mitochondria and endoplasmic reticulum : Similarities in anti-apoptotic functions and differences in regulation.2007
- Author(s)
  Yano, M., et al.
- Journal Title
  
  Exp. Cell Res. 313(17)
  
  Pages: 3767-3778
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14037257
[Journal Article] Mitochondrial import receptors Tom20 and Tom22 have chaperone-like activity2004
- Author(s)
  Yano, M. et al.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 10808-10813
- Data Source
  KAKENHI-PROJECT-14037257
[Presentation] 哺乳類ABCB10のミトコンドリアストレス応答伝達経路への関与に関する解析2016
- Author(s)
  矢野正人、田中遥、福嶋美喜子
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  宮城県　仙台（仙台国際センター）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26460378
[Presentation] TMEM65はプレ配列型のミトコンドリア内膜タンパク質である2014
- Author(s)
  矢野正人、西村尚剛、後藤知己、尾池雄一
- Organizer
  第８７回日本生化学会大会
- Place of Presentation
  京都（国立京都国際会館）
- Year and Date
  2014-10-17
- Data Source
  KAKENHI-PROJECT-26460378
[Presentation] スフィンゴ脂質代謝異常による病態発症機序の解析2012
- Author(s)
  矢野正人
- Organizer
  日本生化学会
- Place of Presentation
  京都（国立京都国際会館）
- Data Source
  KAKENHI-PROJECT-23590340
[Presentation] スフィンゴミエリン合成酵素1欠損マウスにおける脂肪萎縮と酸化ストレスの解析2012
- Author(s)
  矢野正人、山本格士、西村尚剛、加覧洋平、渡辺研、後藤知己、野出孝一、岡崎俊朗、尾池雄一.
- Organizer
  日本生化学会
- Place of Presentation
  博多（福岡国際会議場・マリンメッセ福岡）
- Data Source
  KAKENHI-PROJECT-23590340
[Presentation] スフィンゴミエリン合成酵素1欠損マウスにおける脂肪肝の抑制2012
- Author(s)
  山本格士、矢野正人、西村尚剛、渡辺研、後藤知己、野出孝一、岡崎俊朗、尾池雄一.
- Organizer
  日本生化学会
- Place of Presentation
  博多（福岡国際会議場・マリンメッセ福岡）
- Data Source
  KAKENHI-PROJECT-23590340
[Presentation] Increased reactive oxygen species in sphingomyelin synthase 1 null mice : Relationship between ROS generation and lethality/insulin secretion deficiency/lipoatrophy2010
- Author(s)
  矢野正人, 他
- Organizer
  第83回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21790286
[Presentation] スフィンゴミエリン合成酵素1ノックアウトマウスにおけるROS産生増加と致死性・インスリン分泌不全・脂肪萎縮との関連性の解析2010
- Author(s)
  矢野正人、山本格士、渡部研、池田和貴、瀬ノ口隆文、門松毅、束野寛人、後藤知己、岡崎俊朗、田口良、山縣和也、尾池雄一
- Organizer
  第83回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(口頭発表およびポスター発表)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21790286
[Presentation] スフィンゴミエリン合成酵素1による脂質および糖代謝制御に関する解析2009
- Author(s)
  矢野正人, 他
- Organizer
  日本生化学会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21790286
[Presentation] スフィンゴミエリン合成酵素1による脂質および糖代謝制御に関する解析2009
- Author(s)
  矢野正人、Wang Difei、池田和貴、瀬ノ口隆文、門松毅、山縣和也、田口良、渡部研、尾池雄一
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(ポスター発表)
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21790286
[Presentation] M. Yano Regulation of Bcl-2 activity in mitochondria and endoplasmic reticulum by BH-3 only protein tBid.2007
- Author(s)
  M. Yano
- Organizer
  80^<th> Japan Niochemistry Society Meeting and 30^<th. Japan Molecular Biology Meeting
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2007-12-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037257
[Presentation] BH3-onlyタンパク質によるミトコンドリアおよび小胞体Bcl-2の活性制御2007
- Author(s)
  矢野正人
- Organizer
  第30回日本分子生物学会年会/第80回日本生化学会大会
- Place of Presentation
  パシフイコ横浜
- Year and Date
  2007-12-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14037257
[Presentation] BH3-onlyタンパク質によるミトコンドリアおよび小胞体Bcl-2の活性制御2007
- Author(s)
  矢野正人
- Organizer
  日本生化学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19790215
[Presentation] BH3-onlyタンパク質によるミトコンドリアおよび小胞体Bcl-2の活性制御2007
- Author(s)
  矢野正人,寺田和豊,後藤知己,森正敬
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Data Source
  KAKENHI-PROJECT-19790215

1. KAZUTOYO Terada (00253724)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. MORI Masataka (40009650)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. OIKE Yuichi (90312321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. GOTOH Tomomi (20264286)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 後藤知巳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YANO Masato 矢野 正人

矢野 正人 ヤノ マサト

Research Projects

Research Products

Co-Researchers

Analysis of mitochondrial stress signaling pathwayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

Analysis in the regulation mechanism of oxidative stress by sphingolipidPrincipal Investigator

Principal Investigator

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Research Institution

Regulation of insulin secretion by sphingolipidsPrincipal Investigator

Principal Investigator

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Research Institution

Analysis on activity regulation of Bcl-2 in mitochondria and ERPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

ミトコンドリア外膜タンパク質輪送装置のアポトーシスにおける機能の解析Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

ミトコンドリアタンパク質の外膜透過装置はアポトーシスに関与するか?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of chaperones in mammals

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ミトコンドリアタンパク質の輸送とミトコンドリア形態形成の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies of mitochondrial protein import factors in mammals

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

[Journal Article] ABCB10 depletion reduces unfolded protein response in mitochondria.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mitochondrial inner and outer membrane separation in HeLa cells2014

Author(s)

Journal Title

Data Source

[Journal Article] TMEM65 is a mitochondrial inner-membrane protein.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increased oxidative stress impairs adipose tissue function in sphingomyelin synthase 1 null mice2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mitochondrial Dysfunction and Increased Reactive Oxygen Species Impair Insulin Secretion in Sphingomyelin Synthase 1-null Mice.2011

Author(s)

YANO Masato 矢野正人

矢野正人ヤノマサト