Takahashi Hideyuki 高橋英之

… Alternative Names

高橋英之タカハシヒデユキ

TAKAHASHI Hideyuki 高橋英之

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Researcher Number	60321866
Other IDs
External Links
Affiliation (Current)	2025: 国立感染症研究所, 細菌第一部, 室長
Affiliation (based on the past Project Information) *help	2024: 国立感染症研究所, 細菌第一部, 室長 2019 – 2021: 国立感染症研究所, 細菌第一部, 室長 2016 – 2017: 国立感染症研究所, 細菌第一部, 主任研究官 2013 – 2015: 国立感染症研究所, その他部局等, 研究員 2009 – 2012: National Institute of Infectious Diseases, 細菌第一部, 主任研究官 … More 2004 – 2006: 国立感染症研究所, 細菌第一部, 主任研究官 2002: 国立感染症研究所, 細菌第一部, 研究員 2001: 国立感染症研究所, 細菌部, 研究員 Less
Review Section/Research Field	Principal Investigator Bacteriology (including Mycology) / Basic Section 49050:Bacteriology-related / Bacteriology (including mycology) / Bacteriology (including Mycology) Except Principal Investigator Pathobiological dentistry/Dental radiology / Social dentistry
Keywords	Principal Investigator 髄膜炎菌 / Neisseria meningitidis / 病原性 / 感染 / 非天然アミノ酸 / 分類マーカー / γ-glutamyl aminopeptidase / 遺伝暗号拡張 / 機能未知因子 / Methanosarcina mazei … More / クロスリンカー / PamA / Neisseria meningitides / 線毛 / クロスリンク / 外膜タンパク / 機能未知 / 病原性因子 / 侵襲性感染症 / 脳血管内皮細胞 / 莢膜多糖体合成遺伝子 / 臨床分離株 / アミノ酸 / ヒト脳血管内皮細胞 / グルタチオン / ヒト培養細胞 / システイン / 細胞内 / ヒト / 侵入 / ヒト内皮細胞 / 転写後制御 / 宿主細胞侵入 / 細胞侵入 / トランスポーター / グルタミン酸 / signature tag mutagenesis / 変異株 / トランスポゾン変異 / Signature Tag Mutagenesis / 病原因子 / 微生物 / 感染症 / multilocus sequence typing / g-glutamyl aminopeptidase / 髄液 / 生物進化 / 偽遺伝子 / Neisseria gonorrhoeae / tetB遺伝子 / tetaracycline高度耐性株 … More Except Principal Investigator 粘膜免疫 / 外膜ヴェシクル / 免疫 / 歯周病 / 韓国：米国 / 高齢者 / 老年歯科 / 韓国:米国 / 国際研究者交流 / 検出方法 / 細菌 / 感染症 Less

非天然アミノ酸クロスリンカーを用いた髄膜炎菌の機能不明因子を介した病原機構の解明Principal Investigator
- Principal Investigator
  
  高橋英之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  National Institute of Infectious Diseases
Functional analyses of unknown factors related to meningococcal pathogenesis with unnatural amino acidsPrincipal Investigator
- Principal Investigator
  
  Takahashi Hideyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  National Institute of Infectious Diseases
Identification of meningococcal virulence factors and the expression profile by using clinical isolatesPrincipal Investigator
- Principal Investigator
  
  Takahashi Hideyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  National Institute of Infectious Diseases
Immunopathology of outer membrane vesicles of periodontopathic bacteria
- Principal Investigator
  
  NAKAO Ryoma
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  National Institute of Infectious Diseases
Systematic analyses of signal transduction systems on GltT-GltM glutamate transporter mediated invasion into the host cell in Neisseria meningitidisPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Hideyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  National Institute of Infectious Diseases
Application of New Generation Respiratory Pathogens Detection System to Elderly in Aspiration Pneumonia Prevention
- Principal Investigator
  
  SEKI Mitsuko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Social dentistry
- Research Institution
  Nihon University
Screening for a new meningococcal pathogenic factor by STMPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Hideyuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  National Institute of Infectious Diseases
分子疫学的に同定された病原性髄膜炎菌株を用いた新規病原因子の単離・同定Principal Investigator
- Principal Investigator
  
  高橋英之
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  National Institute of Infectious Diseases
髄膜炎菌の宿主細胞侵入性に関与する新規病原因子の探索Principal Investigator
- Principal Investigator
  
  高橋英之
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  National Institute of Infectious Diseases

[Book] 小児疾患診療のための病態生理1 「侵襲性髄膜炎菌感染症」2020
- Author(s)
  高橋英之、大西真
- Total Pages
  5
- Publisher
  東京医学社
- Data Source
  KAKENHI-PROJECT-19K07550
[Book] 臨床と微生物　「侵襲性髄膜炎菌感染症」2020
- Author(s)
  高橋英之、大西真
- Total Pages
  5
- Publisher
  近代出版
- ISBN
  9784874022634
- Data Source
  KAKENHI-PROJECT-19K07550
[Book] 髄膜炎菌　日常診断に役立つ小児感染症マニュアル2017
- Author(s)
  高橋英之、大西真
- Total Pages
  6
- Publisher
  日本小児感染症学会
- Data Source
  KAKENHI-PROJECT-15K08485
[Book] 髄膜炎菌による感染症、中学保健ニュース2017
- Author(s)
  高橋英之
- Total Pages
  1
- Publisher
  少年写真新聞
- Data Source
  KAKENHI-PROJECT-15K08485
[Book] 侵襲性髄膜炎菌性感染症の現状と基礎知識2017
- Author(s)
  高橋英之
- Total Pages
  1
- Publisher
  少年写真新聞
- Data Source
  KAKENHI-PROJECT-15K08485
[Book] 髄膜炎菌感染症2016
- Author(s)
  高橋英之、大西真
- Total Pages
  6
- Publisher
  金原出版株式会社
- Data Source
  KAKENHI-PROJECT-15K08485
[Book] 小児疾患診療のための病態生理2014
- Author(s)
  高橋英之、大西真
- Total Pages
  1111
- Publisher
  東京医学社
- Data Source
  KAKENHI-PROJECT-24590545
[Book] 病原体の今日的意味、髄膜炎菌2013
- Author(s)
  高橋英之、大西真
- Total Pages
  8
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-24590545
[Book] 侵襲性髄膜炎菌感染症2013
- Author(s)
  高橋英之、大西真
- Total Pages
  4
- Publisher
  日本臨床
- Data Source
  KAKENHI-PROJECT-24590545
[Book] 髄膜炎菌性髄膜炎（侵襲性髄膜炎菌感染症）2013
- Author(s)
  高橋英之
- Total Pages
  6
- Publisher
  少年写真新聞
- Data Source
  KAKENHI-PROJECT-24590545
[Book] 感染症辞典2012
- Author(s)
  川端寛樹、高橋英之
- Publisher
  オーム社
- Data Source
  KAKENHI-PROJECT-21790435
[Book] 感染症辞典3-27ペスト2012
- Author(s)
  川端寛樹、高橋英之
- Total Pages
  5
- Publisher
  オーム社
- Data Source
  KAKENHI-PROJECT-21790435
[Book] 侵襲性髄膜炎菌感染症の最近の問題点 / 小児科2012
- Author(s)
  高橋英之、大西真
- Total Pages
  127
- Publisher
  金原出版株式会社
- Data Source
  KAKENHI-PROJECT-24590545
[Book] 病原菌の今日的意味14.髄膜炎菌2011
- Author(s)
  高橋英之、大西真
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-21790435
[Journal Article] Genetic characterization of clonal complex sequence type 2057 (cc2057) serogroup B Neisseria meningitidis strains unique to Japan and identification of a capsular-switched serogroup Y isolate cc20572022
- Author(s)
  Hideyuki Takahashi, Masatomo Morita, Hajime Kamiya, Haruna Nakamura-Miwa, Ken Shimuta, and Makoto Ohnishi
- Journal Title
  
  Journal of Medical Microbiology
  
  Volume: 71 Issue: 3 Pages: 001504-001504
- DOI
  10.1099/jmm.0.001504
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07550
[Journal Article] Serogroup B invasive meningococcal disease (IMD) outbreak at a Japanese high school dormitory: An outbreak investigation report from the first IMD outbreak in decades2021
- Author(s)
  Noritaka Sekiya, Tomimasa Sunagawa, Hideyuki Takahashi, Hajime Kamiya, Shuji Yoshino, Makoto Ohnishi, Nobuhiko Okabe, Kiyosu Taniguchi
- Journal Title
  
  Vaccine
  
  Volume: 39 Issue: 15 Pages: 2177-2182
- DOI
  10.1016/j.vaccine.2021.02.034
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07550
[Journal Article] Genetic incorporation of non-canonical amino acids photocrosslinkers in Neisseria meningitidis: New method provides insights into the physiological function of the function-unknown NMB1345 protein.2020
- Author(s)
  Takahashi H, Dohmae N, Kim KS, Shimuta K, Ohnishi M, Yokoyama S, Yanagisawa T.
- Journal Title
  
  PLoS ONE
  
  Volume: 15 Issue: 8 Pages: e0237883-e0237883
- DOI
  10.1371/journal.pone.0237883
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07550
[Journal Article] Characterization of two Neisseria gonorrhoeae strains with high-level azithromycin resistance isolated in 2015 and 2018 in Japan2020
- Author(s)
  Shimuta Ken、Lee Kenichi、Yasuda Mitsuru、Furubayashi Keiichi、Uchida Chiaki、Nakayama Shu-ichi、Takahashi Hideyuki、Ohnishi Makoto
- Journal Title
  
  Sexually Transmitted Diseases
  
  Volume: Publish Ahead of Print Issue: 7 Pages: 1-5
- DOI
  10.1097/olq.0000000000001303
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09163, KAKENHI-PROJECT-19K07550, KAKENHI-PROJECT-18H02659
[Journal Article] A Loop-Mediated Isothermal Amplification Assay Targeting Neisseria Gonorrhoeae penA-60.0012019
- Author(s)
  Ken Shimuta, Shu-Ichi Nakayama, Hideyuki Takahashi, Makoto Ohnishi
- Journal Title
  
  Antimicrob Agents Chemother .
  
  Volume: 64 Issue: 1
- DOI
  10.1128/aac.01663-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07550, KAKENHI-PROJECT-18H02659, KAKENHI-PROJECT-16K11061
[Journal Article] Structural basis of protein arginine rhamnosylation by glycosyltransferase EarP2018
- Author(s)
  Sengoku Toru、Suzuki Takehiro、Dohmae Naoshi、Watanabe Chiduru、Honma Teruki、Hikida Yasushi、Yamaguchi Yoshiki、Takahashi Hideyuki、Yokoyama Shigeyuki、Yanagisawa Tatsuo
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 14 Issue: 4 Pages: 368-374
- DOI
  10.1038/s41589-018-0002-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K21626, KAKENHI-PROJECT-15K08485, KAKENHI-PROJECT-18K19305, KAKENHI-PROJECT-16H03293, KAKENHI-PROJECT-16K05859, KAKENHI-PROJECT-16H04758
[Journal Article] Invasive meningococcal disease due to ciprofloxacin-resistant Neisseria meningitidis sequence type 4821: the first case in Japan.2018
- Author(s)
  Yu Kawasaki, Kousaku Matsubara, Hideyuki Takahashi, Masatomo Morita, Makoto Ohnishi, Masayuki Hori, Kenichi Isome, Aya Iwata, Hiroyuki Nigami, Go Yamamoto, Kiyofumi Ohkusu.
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 24 Issue: 4 Pages: 305-308
- DOI
  10.1016/j.jiac.2017.11.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08485
[Journal Article] Meningococcal meningitis with neurological complications and meningococcemia due to serogroup W sequence type 11 complex.2018
- Author(s)
  Nobuaki Mori, Tomofumi Hayashi, Hideki Nakamura, Hideyuki Takahashi.
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 24 Issue: 5 Pages: 398-400
- DOI
  10.1016/j.jiac.2017.12.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08485
[Journal Article] Meningococcal disease outbreak related to the World Scout Jamboree in Japan, 2015.2017
- Author(s)
  Kanai M, Kamiya H, Smith-Palmer A, Takahashi H, Hachisu Y, Fukusumi M, et al.
- Journal Title
  
  Western pacific Surveillance and Response
  
  Volume: 8 Issue: 2 Pages: 1-6
- DOI
  10.5365/wpsar.2016.7.3.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08485
[Journal Article] Genomic characterization of urethritis-associated Neisseria meningitidis shows that a wide range of N. meningitidis strains can cause urethritis.2017
- Author(s)
  Kevin Ma, Magnus Unemo, Samo Jeverica, Bob Kirkcaldy, Hideyuki Takahashi, Makoto Ohnishi, and Yonatan Grad
- Journal Title
  
  Journal of Clinical Microbiology
  
  Volume: 55 Issue: 12 Pages: 3374-3383
- DOI
  10.1128/jcm.01018-17
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08485
[Journal Article] Novel Loop-Mediated Isothermal Amplification Assay for Serogroup Identification of Neisseria meningitidis in Cerebrospinal Fluid2016
- Author(s)
  Lee DK, Kim EJ, Kilgore P, Takahashi H, Ohnishi M, Tomono J, Miyamoto S, Omagari D, Kim DW and Seki M.
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 6 Pages: 1548-1548
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08485
[Journal Article] A Novel Loop-Mediated Isothermal Amplification Assay for Serogroup Identification of Neisseria meningitidis in Cerebrospinal Fluid.2016
- Author(s)
  Do Kyung Lee1, Eun Jin Kim, PaulE Kilgore, Hideyuki Takahashi, Makoto Ohnishi, Jun Tomono, Shigehiko Miyamoto, Daisuke Omagari, Dong Wook Kim and Mitsuko Seki.
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 6 Pages: 1548-1548
- DOI
  10.3389/fmicb.2015.01548
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08485
[Journal Article] National surveillance for meningococcal disease in Japan2016
- Author(s)
  Fukusumi M, Kamiya H, Takahashi H, Kanai M, Hachisu Y, Saitoh T, Ohnishi M, Oishi K, Sunagawa T.
- Journal Title
  
  Vaccine
  
  Volume: 34 Pages: 4068-4071
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08485
[Journal Article] Neisseria meningitidis Translation Elongation Factor P and Its Active-Site Arginine Residue Are Essential for Cell Viability2016
- Author(s)
  Yanagisawa T, Takahashi H, Suzuki T, Masuda A, Dohmae N, Yokoyama S.
- Journal Title
  
  PLoS ONE
  
  Volume: 11(2) Issue: 2 Pages: e0147907-e0147907
- DOI
  10.1371/journal.pone.0147907
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26410190, KAKENHI-PROJECT-15K08485
[Journal Article] Meningococcal carriage rates in healthy individuals in Japan determined using Loop-Mediated Isothermal Amplification and oral throat wash specimens.2016
- Author(s)
  Takahashi H, Haga M, Sunagawa T, Saitoh T, Kitahara T, Matsumoto S, Ohnishi M.
- Journal Title
  
  J Infect Chemotherapy
  
  Volume: 22 Pages: 501-504
- Open Access
- Data Source
  KAKENHI-PROJECT-15K08485
[Journal Article] Multiple Functions of Glutamate Uptake via Meningococcal GltT-GltM　L-Glutamate ABC Transporter in Neisseria meningitidis　Internalization into Human Brain Microvascular Endothelial Cells.2015
- Author(s)
  Takahashi H, Yanagisawa T, Kim KS, Yokoyama S, Ohnishi M.
- Journal Title
  
  Infection and Immunity
  
  Volume: 83 Issue: 9 Pages: 35553567-35553567
- DOI
  10.1128/iai.00654-15
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08485
[Journal Article] Clinical Evaluation of a Loop-Mediated Isothermal Amplification (LAMP) Assay for Rapid Detection of Neisseria meningitidis in Cerebrospinal Fluid.2015
- Author(s)
  DoKyung Lee, Eun Jin Kim, Paul E. Kilgore, Soon Ae Kim, Hideyuki Takahashi, Makoto Ohnishi, Dang Duc Anh, Bai Qing Dong, Jung Soo Kim, Jun Tomono, Shigehiko Miyamoto, Tsugunori Notomi, Dong Wook Kim, Mitsuko Seki.
- Journal Title
  
  Plos One
  
  Volume: 10 Issue: 4 Pages: e0122922-e0122922
- DOI
  10.1371/journal.pone.0122922
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08485
[Journal Article] Urethritis Caused by Novel Neisseria meningitidis Serogroup W in Man Who Has Sex with Men, Japan.2014
- Author(s)
  Hayakawa K, Itoda I, Shimuta K, Takahashi H, Morita M, Ohnishi M.
- Journal Title
  
  Emerging Infectious Diseases
  
  Volume: 20 Issue: 9 Pages: 1585-1587
- DOI
  10.3201/eid2009.140349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590545
[Journal Article] Meningococcemia due to the 2000 Hajj-Associated Outbreak Strain (Serogroup W-135 ST-11) with Immunoreactive Complications2013
- Author(s)
  Kei Yamamoto, Yasuyuki Kato, Takuma Shindo, Mugen Ujiie, Nozomi Takeshita, Shuzo Kanagawa, Junwa Kunimatsu, Yuiichi Tamori, Toshikazu Kano, Rumi Okuno, Hideyuki Takahashi, Norio Ohmagari.
- Journal Title
  
  Jpn J Infect Dis
  
  Volume: 66 Issue: 5 Pages: 443-445
- DOI
  10.7883/yoken.66.443
- NAID
  130003381726
- ISSN
  1344-6304, 1884-2836
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590545
[Journal Article] Meningococcal PilV potentiates Neisseria meningitidis type IV pilus-mediated internalization into human endothelial and epithelial cells.2012
- Author(s)
  Hideyuki Takahashi, Tatsuo Yanagisawa, Kwang Sik Kim, Shigeyuki Yokoyama and Makoto Ohnishi
- Journal Title
  
  Infection and Immunity
  
  Volume: 80 Issue: 12 Pages: 4154-4166
- DOI
  10.1128/iai.00423-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590545
[Journal Article] Meningococcal internalization into human endothelial and epithelial cells is triggered by the influx of extracellular L-glutamate via GltT L-glutamate ABC transporter in Neisseria meningitides2011
- Author(s)
  H.Takahashi, K.S.Kim, H.Watanabe
- Journal Title
  
  Infection and Immunity
  
  Volume: 79 Pages: 380-392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790435
[Journal Article] Meningococcal internalization into human endothelial and epithelial cell-s is triggered by the influx of extracellular L-glutamate via GltT L-glutamate ABC transporter in Neisseria meningitidis2011
- Author(s)
  H. Takahashi, K. S. Kim and H. Watanabe
- Journal Title
  
  Infection and Immunity
  
  Volume: 79 Issue: 1 Pages: 380-392
- DOI
  10.1128/iai.00497-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790435
[Journal Article] Immunomoduatory effects of Yerisinia pestis Lipopolysaccharideson human Macrophages2010
- Author(s)
  M. Matsuura, H. Takahashi, H. Watanabe, K. Kawahara
- Journal Title
  
  Clinical and Vaccine Immunology 17
  
  Pages: 49-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790435
[Journal Article] Immunomoduatory effects of Yerisinia pestis Lipopolysaccharides on human Macrophages2010
- Author(s)
  M. Matsuura, H. Takahashi, H. Watanabe and K. Kawahara
- Journal Title
  
  Clinical and Vaccine Immunology
  
  Volume: 17 Issue: 1 Pages: 49-55
- DOI
  10.1128/cvi.00336-09
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790435
[Journal Article] Development of a Real-Time PCR Assay for Detection of gyrA Mutations Associated with Reduced Susceptibility to Ciprofloxacin in Salmonella enterica Serovar Typhi and Paratyphi A.2006
- Author(s)
  M.Morita, K.Ito, K.Hirose, H.Takahashi, K.Shimuta, J.Terajima, M.Ohnishi, M.Harada, M.Matsuzaki, H.Watanabe, H.Izumiya
- Journal Title
  
  Microbiology and Immunology 50
  
  Pages: 707-711
- NAID
  10018043245
- Data Source
  KAKENHI-PROJECT-16790265
[Journal Article] わが国の健康者における髄膜炎菌の保有状況2005
- Author(s)
  田中博, 他16名(高橋英之:17名中13番目)
- Journal Title
  
  感染症学雑誌 79・8
  
  Pages: 527-533
- Data Source
  KAKENHI-PROJECT-16790265
[Journal Article] A case of serogroup A meningococcal meningitis : A case Possibly imported from China2005
- Author(s)
  Y.Suto, N.Mori, H.Takahashi, H.Watanabe, K.Nishijima
- Journal Title
  
  Internal Medicine 44・9
  
  Pages: 1016-1016
- NAID
  130000076328
- Data Source
  KAKENHI-PROJECT-16790265
[Journal Article] A gonococcal homologue of meningococcal γ-glutamyl transpeptidase gene is a new type of bacterial pseudogene that is transcriptionally active but phenotypically silent2005
- Author(s)
  Hideyuki Takahashi, Haruo Watanabe
- Journal Title
  
  BMC Microbiology 5
  
  Pages: 56-56
- Data Source
  KAKENHI-PROJECT-16790265
[Journal Article] Examination of reliability of meningococcal γ-glutamyl aminopeptidase that is an identification marker for Neissaria meningitidis2004
- Author(s)
  Hideyuki Takahashi et al.
- Journal Title
  
  Microbiology and Immunology 48
  
  Pages: 485-487
- Data Source
  KAKENHI-PROJECT-16790265
[Journal Article] ワクチン-その開発と将来展望、髄膜炎菌ワクチン2004
- Author(s)
  高橋英之, 渡辺治雄
- Journal Title
  
  臨床検査 48
  
  Pages: 441-448
- Data Source
  KAKENHI-PROJECT-16790265
[Journal Article] Post-translational processing of Neisseria meningitidis γ-glutamyl aminopeptidase and its association with inner membrane facing to the cytoplasmic space.2004
- Author(s)
  Hideyuki Takahashi, Haruo Watanabe
- Journal Title
  
  FEMS Microbiology Letters 234
  
  Pages: 27-35
- Data Source
  KAKENHI-PROJECT-16790265
[Journal Article] Necessity of meningococcal γ-glutamyl aminopeptidase for Neisseria meningitidis growth in rat cerebrospinal fluid (CSF) and CSF-like medium2004
- Author(s)
  Hideyuki Takahashi, Kenji Hirose, Haruo Watanabe
- Journal Title
  
  Journal of Bacteriology 186
  
  Pages: 253-257
- Data Source
  KAKENHI-PROJECT-16790265
[Journal Article] Characterization of Neissaria meningitidis isolates collected from 1974 to 2003 in Japan by multilocus sequence typing2004
- Author(s)
  Hideyuki Takahashi et al.
- Journal Title
  
  Jounal of Medical Microbiology 53
  
  Pages: 657-662
- Data Source
  KAKENHI-PROJECT-16790265
[Presentation] Genetic incorporation of non-canonical amino acid photocrosslinkers in Neisseria meningitidis provides insights into the physiological function of the function-unknown protein.2022
- Author(s)
  Hideyuki Takahashi, Makoto Ohnishi, Ken Shimuta, Shigeyuki Yokoyama, Tatsuo Yanagisawa
- Organizer
  第95回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-19K07550
[Presentation] 「マスギャザリングと感染症事例から学ぶ」侵襲性髄膜炎菌感染症2020
- Author(s)
  高橋英之
- Organizer
  第94会日本感染症学会総会
- Data Source
  KAKENHI-PROJECT-19K07550
[Presentation] 非天然アミノ酸を導入した髄膜炎菌における遺伝暗号拡張2020
- Author(s)
  高橋英之、大西真、横山茂之、柳沢達男
- Organizer
  第93回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-19K07550
[Presentation] マスギャザリングと髄膜炎菌感染症2020
- Author(s)
  高橋英之
- Organizer
  第32回地方衛生研究所全国協議会関東甲信静支部細菌研究部会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07550
[Presentation] 髄膜炎菌Neisseria meningitidis の宿主細胞感染時におけるNutrient virulence factor としてのシステイン輸送システムの機能解析2019
- Author(s)
  高橋英之、横山茂之、柳沢達男
- Organizer
  第92回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-19K07550
[Presentation] 臨床分離株の宿主細胞への侵襲能と細胞外因子の発現量の相互比較による髄膜炎菌の病原性因子の探索及び解析2018
- Author(s)
  高橋英之、柳沢達男、横山茂之
- Organizer
  第90回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-15K08485
[Presentation] 反転型糖鎖転移酵素によるタンパク質アルギニン・ラムノシル化の構造基盤2017
- Author(s)
  仙石徹、鈴木健裕、堂前直、渡邉千鶴、本間光貴、疋田泰士、山口芳樹、高橋英之、柳沢達男、横山茂之
- Organizer
  ComBio2017
- Data Source
  KAKENHI-PROJECT-15K08485
[Presentation] 髄膜炎菌由来の翻訳因子EF-Pのラムノース修飾による活性化の構造的基盤2017
- Author(s)
  仙石徹、鈴木健裕、堂前直、渡邉千鶴、本間光貴、疋田泰士、山口芳樹、高橋英之、横山茂之、柳沢達男
- Organizer
  ComBio2017
- Data Source
  KAKENHI-PROJECT-15K08485
[Presentation] 咽頭うがい液を用いた髄膜炎菌の健康者保菌調査の実施2017
- Author(s)
  高橋英之、羽賀將衛、砂川富正、齋藤剛仁、北原武尊、松本壮吉、大西真
- Organizer
  日本細菌学会総会
- Place of Presentation
  仙台市
- Year and Date
  2017-03-19
- Data Source
  KAKENHI-PROJECT-15K08485
[Presentation] 侵襲性髄膜炎菌感染症の世界及び国内の実態2016
- Author(s)
  高橋英之
- Organizer
  日本細菌学会
- Place of Presentation
  大阪国際交流センター
- Year and Date
  2016-03-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08485
[Presentation] Multiple functions of glutamate uptake via meningococcal GltT-GltM L-glutamate ABC transporter for Neisseria meningitidis internalization into human brain microvascular endothelial cells.2016
- Author(s)
  Hideyuki Takahashi, Tatsuo Yanagisawa, Kwang Sik Kim, Shigeyuki Yokoyama　and Makoto Ohnishi.
- Organizer
  International Pathogenic Neisseria Conference
- Place of Presentation
  Manchester UK
- Year and Date
  2016-09-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08485
[Presentation] ltT-GltMトランスポーターを介した髄膜炎菌の宿主細胞侵入に関与する遺伝子の転写及び翻訳レベルでの網羅的解析2014
- Author(s)
  高橋英之
- Organizer
  日本細菌学会年会
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-24590545
[Presentation] 髄膜炎菌の線毛のマイナータンパクPilVの宿主細胞感染における遺伝学的及び物理化学的手法を用いた機能解析2012
- Author(s)
  高橋英之、大西真
- Organizer
  第85回日本細菌学会総会
- Place of Presentation
  長崎
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-21790435
[Presentation] 髄膜炎菌の線毛のマイナータンパクPilVの宿主細胞感染における遺伝学的及び物理化学的手法を用いた機能解析2012
- Author(s)
  高橋英之、大西真
- Organizer
  日本細菌学会総会
- Place of Presentation
  長崎市
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-21790435
[Presentation] 国内分離された髄膜炎菌株の分子役学的解析とそれらを用いたNeisseria meningitidisの病原因子の解析2009
- Author(s)
  高橋英之
- Organizer
  第92回細菌学会関東支部会シンポジウム
- Place of Presentation
  東京医科歯科大学
- Year and Date
  2009-11-08
- Data Source
  KAKENHI-PROJECT-21790435
[Presentation] 国内分離された髄膜炎菌株の分子役学的解析とそれらを用いたNeisseria menlngitidisの病原因子の解析2009
- Author(s)
  高橋英之
- Organizer
  第92回細菌学会関東支部会シンポジウム
- Place of Presentation
  東京都文京区東京医科歯科大学5号館講堂
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-21790435
[Presentation] 細菌感染時の髄膜炎菌の一過的なグルタミン酸の取込みが宿主細胞への侵入に必須である2009
- Author(s)
  高橋英之、渡邉治雄
- Organizer
  第83回日本細菌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-03-24
- Data Source
  KAKENHI-PROJECT-21790435
[Presentation] 細菌感染時の髄膜炎菌の一過的なグルタミン酸の取込みが宿主細胞への侵入に必須である2009
- Author(s)
  高橋英之、渡邉治雄
- Organizer
  第83回日本細菌学会総会
- Place of Presentation
  神奈川県横浜市西区パシフィコ横浜
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-21790435
[Presentation] Glutamate uptake via GltT-GltM glutamate transporter has multiple biological functions for Neisseria meningitidis invasion to the host cells.
- Author(s)
  高橋英之、大西真
- Organizer
  日本細菌学会総会
- Place of Presentation
  長良川国際会議場（岐阜）
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24590545

1. OHNISHI Makoto (10233214)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. YANAGISAWA Tatsuo (10450420)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
3. SEKI Mitsuko (20226640)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. HAGIWARA Yoshiyuki (00228389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SUZUKI Naoto (10226532)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MORINO Tomoko (20582703)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NAKAO Ryoma (10370959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SENPUKU Hidenobu (20250186)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OGATA Yorimasa (90204065)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HIGUCHI Hideo (90165093)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. OOKAWA Katsumasa

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KILGORE Paul, Evan

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KIM Dong, Wook

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KIM Soon

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 仙石徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 益田晶子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 堂前直

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 安田満

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takahashi Hideyuki 高橋 英之

高橋 英之 タカハシ ヒデユキ

TAKAHASHI Hideyuki 高橋 英之

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Co-Researchers

非天然アミノ酸クロスリンカーを用いた髄膜炎菌の機能不明因子を介した病原機構の解明Principal Investigator

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Functional analyses of unknown factors related to meningococcal pathogenesis with unnatural amino acidsPrincipal Investigator

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Identification of meningococcal virulence factors and the expression profile by using clinical isolatesPrincipal Investigator

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Immunopathology of outer membrane vesicles of periodontopathic bacteria

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Systematic analyses of signal transduction systems on GltT-GltM glutamate transporter mediated invasion into the host cell in Neisseria meningitidisPrincipal Investigator

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Application of New Generation Respiratory Pathogens Detection System to Elderly in Aspiration Pneumonia Prevention

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Screening for a new meningococcal pathogenic factor by STMPrincipal Investigator

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分子疫学的に同定された病原性髄膜炎菌株を用いた新規病原因子の単離・同定Principal Investigator

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髄膜炎菌の宿主細胞侵入性に関与する新規病原因子の探索Principal Investigator

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[Book] 小児疾患診療のための病態生理1 「侵襲性髄膜炎菌感染症」2020

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[Book] 臨床と微生物 「侵襲性髄膜炎菌感染症」2020

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[Book] 髄膜炎菌 日常診断に役立つ小児感染症マニュアル2017

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[Book] 髄膜炎菌による感染症、中学保健ニュース2017

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Takahashi Hideyuki 高橋英之

高橋英之タカハシヒデユキ

TAKAHASHI Hideyuki 高橋英之

[Book] 臨床と微生物　「侵襲性髄膜炎菌感染症」2020

[Book] 髄膜炎菌　日常診断に役立つ小児感染症マニュアル2017