Ohtsuki Sumio 大槻純男

… Alternative Names

Researcher Number	60323036
Other IDs	https://orcid.org/0000-0003-4634-7133
External Links
Affiliation (Current)	2022: 熊本大学, 大学院生命科学研究部(薬), 教授
Affiliation (based on the past Project Information) *help	2014 – 2021: 熊本大学, 大学院生命科学研究部(薬), 教授 2017: 熊本大学, 薬学部, 教授 2016: 熊本大学, その他の研究科, 教授 2014 – 2016: 熊本大学, 大学院生命科学研究部, 教授 2015: 熊本大学, 生命科学研究部, 教授 … More
Review Section/Research Field	Principal Investigator Medical pharmacy / Basic Section 47060:Clinical pharmacy-related / 応用薬理学・医療系薬学 / Complex systems / Tumor diagnostics Except Principal Investigator Medical pharmacy / 応用薬理学・医療系薬学 / Basic Section 47060:Clinical pharmacy-related / Biological Sciences / Digestive surgery … More
Keywords	Principal Investigator 血液脳関門 / トランスポーター / プロテオミクス / 脳関門 / 輸送 / DDS / クレアチン / 膜タンパク質 / 質量分析 / 脳毛細血管 … More Except Principal Investigator プロテオミクス / 血液脳関門 / トランスポーター / 脳毛細血管内皮細胞 / 質量分析 / バイオマーカー / アルツハイマー病 / iPS細胞 / siRNA / ABCトランスポーター / 脳脊髄液 / 細胞膜輸送 / 輸送担体 / 条件的不死化細胞 / blood-brain barrier / conditionally immortalized cell line / 膠芽腫 / 血液脳脊髄液関門 / トランスポートソーム / 膜輸送複合体 / P-糖蛋白質 / LXR / P-gp / Mct1 / oatp2 / ABCG2 / LRP-1 / GLUT1 / OAT / 脂質代謝 / コレステロール / 24-S-水酸化コレステロール / リポタンパク質 / ApoE / 蛍光消光法 / 薬物分布 / 基質認識 / MRP4 / MIANS / High Throughput Screenint / ABC transporter / pharmacoproteomics / 標的絶対プロテオミクス / 脳毛細血管 / ファーマコプロテオミクス / MRP / 生理機能 / 磁気分離 / 膵臓外科学 / 膵癌 / 抗癌剤 / メタボロミクス / システム生物学 / 生理学 / 生物物理学 / 心臓 / 不整脈 / 薬物動態 / 全身循環 / 代謝 / 薬物動態学 / 生物物理 / 生物学 / 統合失調症 / 死後脳研究 / 死後脳 / LC-MS/MS / LC-MSMS / レクチン / アミロイドベータ / アミロイド / 神経伝達物質 / 遺伝子クローニング / 中枢解毒 / membrane transport / neurotransmitter / organic anion transporter / cDNA cloning / central nervous system detoxification / brain capillary endothelial cell / 遺伝子発現系 / 培養細胞 / 新薬スクリーニング / plasma membrane / gene expression / culture cell / brain capillary endothelial cells / drug screening / membrane transporter / 中枢疾患 / 制御 / 中枢防御 / 脳内エネルギー / 排出輸送 / 有機アニオン輸送 / 尿毒症 / Oat / Oatp / 周皮細胞 / 密着結合 / アンジオポエチン / Tie2受容体 / アミロイド蛋白 / 有機アニオン輸送系 / アルパラギン酸輸送 / 立体選択性 / ASCT / organic anion transporter3(OAT3) / 酸化的ストレス / system Xc^- / system A / クレアチン輸送系 / 脳内エネルギー蓄積物質 / basic FGF / Blood-brain barrieer / Brain capilary endothelial cells / Transporter / Neural disorders / Regulation / Protection / Energy / Efflux transport / オーファントランスポーター / 細胞老化 / がん / 定量プロテオーム解析 / 細胞増殖 / 細胞浸潤 / p53 / O-グリコシル化 / タンパク質翻訳後修飾 / インスリン抵抗性 / 知的障害 / クレアチン / 先天性代謝異常 / 脳クレアチン欠乏症候群 / 治療薬 / クレアチントランスポーター / 発達障害 / グアニジノ化合物 / クレアチニン / グアニジノ酢酸 / 精神遅滞 / 自閉症 / グリオーマ / 血液 / 糖鎖 / 神経細胞 / CYLD / 個別化医療 / 分子標的治療薬 / 薬剤感受性 / 遺伝子増幅 / コピー数変化 / ゲノム / BHLHE41 / オートファジー / がん抑制遺伝子 / 細胞死 / 肺がん / コピー数 / 薬剤耐性 Less

New molecular mechanisms for membrane-mediated transcellular transport across the blood brain barrierPrincipal Investigator
- Principal Investigator
  
  大槻純男
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kumamoto University
増幅遺伝子のコピー数の制御機構の解明
- Principal Investigator
  
  古川龍彦
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Kagoshima University
Diagnosis of Alzheimer's disease by plasma
- Principal Investigator
  
  城谷圭朗
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagasaki University
Mcrotransport of the blood-brain barrier and its application to the permeable carrier.Principal Investigator
- Principal Investigator
  
  OHTSUKI Sumio
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kumamoto University
癌の生命予後規定因子CYLDの分子診断を突破口とした従来にない分子標的治療の確立
- Principal Investigator
  
  城野博史
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kumamoto University
Regulation mechanism of cell senescence by orphan transporter
- Principal Investigator
  
  ITO Shingo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kumamoto University
Elucidation of pemeable mechanism of new intestinal permeable peptidePrincipal Investigator
- Principal Investigator
  
  OHTSUKI Sumio
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Kumamoto University
Exploration of blood biomarker for glioblastoma
- Principal Investigator
  
  Nakada Mitsutoshi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurosurgery
- Research Institution
  Kanazawa University
Identification of the biomarker in cerebrospinal fluid of glioblastoma by innovative proteomics
- Principal Investigator
  
  Furuta Takuya
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Kurume University
  Kanazawa University
Mechanism of cellular localization of mutated creatine transporter toward therapy for creatine deficiency syndromesPrincipal Investigator
- Principal Investigator
  
  Ohtsuki Sumio
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kumamoto University
Study on biomarkers of Alzheimer's disease for personalized medicine
- Principal Investigator
  
  SHIROTANI Keiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagasaki University
Ultra-deep quantitative proteomics with RT-normalized peptide databasePrincipal Investigator
- Principal Investigator
  
  Ohtsuki Sumio
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor diagnostics
- Research Institution
  Kumamoto University
Study for Pathogenesis of Cerebral Creatine Deficiency Syndromes
- Principal Investigator
  
  WADA Takahito
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto University
Global and target-oriented proteomic analysis in the postmortem brains from patients with schizophrenia
- Principal Investigator
  
  KUNII Yasuto
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Fukushima Medical University
Establishment of Integrative Multi-level Systems Biology and its Applications
- Principal Investigator
  
  KURACHI YOSHIHISA
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Osaka University
小分子生体内挙動を制御する因子の組織・臓器階層における網羅的解析Principal Investigator
- Principal Investigator
  
  大槻純男
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Tohoku University
標的オミクス融合による新しい薬物トランスポーター解析戦略の構築Principal Investigator
- Principal Investigator
  
  大槻純男
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tohoku University
The prediction to overcome the drug resistance in pancreatic cancers by proteomics and metaboromics.
- Principal Investigator
  
  MOTOI Fuyuhiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Tohoku University
バイオインフォマティックスとプロテオミクスを駆使した新規薬物輸送担体の同定戦略Principal Investigator
- Principal Investigator
  
  大槻純男
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Tohoku University
Prediction of drug distribution into the brain by the model with intrinsic transporter activityPrincipal Investigator
- Principal Investigator
  
  OHTSUKI Sumio
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tohoku University
PROTEOMICS-BASED ANALYSIS OF BLOOD-BRAIN BARRIER TRANSPORT SYSTEM
- Principal Investigator
  
  TERASAKI Tetsuya (TETSUYA Terasaki)
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tohoku University
Physiological role of the blood-brain barrier transportsome
- Principal Investigator
  
  TERASAKI Tetsuya
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
蛍光標識化MRP4/ABCC4を用いた新薬スクリーニング系の開発
- Principal Investigator
  
  寺崎哲也
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Tohoku University
Analysis of blood-brain barrier transport system as the CNS elimination system for neurotoxinsPrincipal Investigator
- Principal Investigator
  
  OHTSUKI Sumio
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tohoku University
Physiological study on the transport functions at the blood-brain barrier relating to neural disorders.
- Principal Investigator
  
  TERASAKI Tetsuya
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Tohoku University
脳関門を介したクレアチンの脳移行メカニズムの解明Principal Investigator
- Principal Investigator
  
  大槻純男
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Tohoku University
cDNA cloning of blood-brain barrier neurotransmitter transporter and analysis of its physiological function
- Principal Investigator
  
  TERASAKI Tetsuya
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Tohoku University
Development of new drug screening system using the blood-brain barrier transporter gene expression
- Principal Investigator
  
  TERASAKI Tetsuya
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  Tohoku University

[Book] 血液脳関門、血液脳脊髄液関門、「分子薬物動態学」2008
- Author(s)
  大槻純男
- Total Pages
  14
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-18109002
[Book] A novel relationship between creatine transport at the blood-brain and blood-retinal barriers, Creatine biosynthesis, and its use for brain and retinal energy homeostasis2007
- Author(s)
  M. Tachikawa, K. Hosoya, S. Ohtsuki, T. Terasaki
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-17081002
[Book] 血液脳関門の輸送機構と脳支援・防御システムとしての生理的役割、脳室とその周囲器官、[神経科学の基礎と臨床シリーズ11巻]2002
- Author(s)
  大槻純男
- Total Pages
  23
- Publisher
  ブレーン出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] Novel cyclic peptides facilitating transcellular blood-brain barrier transport of macromolecules in vitro and in vivo2020
- Author(s)
  1.Shunsuke Yamaguchi, Shingo Ito, Takeshi Masuda, Pierre-Olivier Couraud, Sumio Ohtsuki
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 321 Pages: 744-755
- DOI
  10.1016/j.jconrel.2020.03.001
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18J15384, KAKENHI-PROJECT-19K05544, KAKENHI-PROJECT-18H02590
[Journal Article] Efficient isolation of brain capillary from a single frozen mouse brain for protein expression analysis2020
- Author(s)
  Ogata Seiryo、Ito Shingo、Masuda Takeshi、Ohtsuki Sumio
- Journal Title
  
  Journal of Cerebral Blood Flow & Metabolism
  
  Volume: 41 Pages: 1026-1038
- DOI
  10.1177/0271678x20941449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05544, KAKENHI-PROJECT-18H02590
[Journal Article] Identification of Cell-Surface Proteins Endocytosed by Human Brain Microvascular Endothelial Cells In Vitro2020
- Author(s)
  Ito Shingo、Oishi Mariko、Ogata Seiryo、Uemura Tatsuki、Couraud Pierre-Olivier、Masuda Takeshi、Ohtsuki Sumio
- Journal Title
  
  Pharmaceutics
  
  Volume: 12 Pages: 579-579
- DOI
  10.3390/pharmaceutics12060579
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05544, KAKENHI-PROJECT-18H02590
[Journal Article] Changes of Blood-Brain Barrier and Brain Parenchymal Protein Expression Levels of Mice under Different Insulin-Resistance Conditions Induced by High-Fat Diet2019
- Author(s)
  Ogata S, Ito S, Masuda T, Ohtsuki S
- Journal Title
  
  Pharmaceutical Research
  
  Volume: 36 Pages: 1-12
- DOI
  10.1007/s11095-019-2674-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02590, KAKENHI-PROJECT-19K05544
[Journal Article] Knockdown of Orphan Transporter SLC22A18 Impairs Lipid Metabolism and Increases Invasiveness of HepG2 Cells2019
- Author(s)
  Ito S, Honda G, Fujino Y, Ogata S, Hirayama-Kurogi M, Ohtsuki S
- Journal Title
  
  Pharmaceutical research
  
  Volume: 36 Pages: 39-39
- DOI
  10.1007/s11095-018-2565-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08373
[Journal Article] Large-Scale Quantitative Comparison of Plasma Transmembrane Proteins between Two Human Blood?Brain Barrier Model Cell Lines, hCMEC/D3 and HBMEC/ciβ2019
- Author(s)
  Masuda T, Hoshiyama T, Uemura T, Hirayama-Kurogi M, Ogata S, Furukawa A, Couraud PO, Furihata T, Ito S, Ohtsuki S
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 16 Pages: 2162-2171
- DOI
  10.1021/acs.molpharmaceut.9b00114
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02590, KAKENHI-PROJECT-19K05544
[Journal Article] Identification of blood biomarkers in glioblastoma by SWATH mass spectrometry and quantitative targeted absolute proteomics2018
- Author(s)
  Miyauchi E, Furuta T, Ohtsuki S, Tachikawa M, Uchida Y, Sabit H, Obuchi Wm Baba T, Watanabe M, Terasaki T, Nakada M
- Journal Title
  
  PLOS ONE
  
  Volume: 13
- DOI
  10.1371/journal.pone.0193799
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15012, KAKENHI-PROJECT-16H06218, KAKENHI-PROJECT-16K15645
[Journal Article] Involvement of an Orphan Transporter, SLC22A18, in Cell Growth and Drug Resistance of Human Breast Cancer MCF7 Cells.2018
- Author(s)
  Ito S, Fujino Y, Ogata S, Hirayama-Kurogi M, Ohtsuki S
- Journal Title
  
  Journal of pharmaceutical sciences
  
  Volume: 107 Pages: 3163-3170
- DOI
  10.1016/j.xphs.2018.08.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08373
[Journal Article] Abnormal <i>N</i>-Glycosylation of a Novel Missense Creatine Transporter Mutant, G561R, Associated with Cerebral Creatine Deficiency Syndromes Alters Transporter Activity and Localization2017
- Author(s)
  T. Uemura, S. Ito, Y. Ohta, M. Tachikawa, T. Wada, T. Terasaki, S. Ohtsuki
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 40 Issue: 1 Pages: 49-55
- DOI
  10.1248/bpb.b16-00582
- NAID
  130005188881
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293035, KAKENHI-PROJECT-26461544
[Journal Article] Identification of cyclic peptides for facilitation of transcellular transport of phages across intestinal epithelium in vitro and in vivo2017
- Author(s)
  Yamaguchi Shunsuke、Ito Shingo、Kurogi-Hirayama Mio、Ohtsuki Sumio
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 262 Pages: 232-238
- DOI
  10.1016/j.jconrel.2017.07.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15162
[Journal Article] Attenuation of Phosphorylation by Deoxycytidine Kinase is Key to Acquired Gemcitabine Resistance in a Pancreatic Cancer Cell Line : Targeted Proteomic and Metabolomic Analyses in PK9 Cells2012
- Author(s)
  Ohmine K, Kawaguchi K, Ohtsuki S, Motoi F, et al
- Journal Title
  
  Pharm Res
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591766
[Journal Article] Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors2011
- Author(s)
  Y. Uchida, S. Ohtsuki, Y. Katsukura, C. Ikeda, T. Suzuki, J. Kamiie, T. Terasaki
- Journal Title
  
  J Neurochem
  
  Volume: 117(2) Pages: 333-345
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] Simultaneous absolute quantification of 11 cytochrome P450 isoforms in human liver microsomes by liquid chromatography tandem mass spectrometry with in silico target peptide selection2011
- Author(s)
  Hirotaka Kawakami, Sumio Ohtsuki, Junichi Kamiie, Takashi Suzuki, Takaaki Abe, Tetsuya Terasaki
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 100 Pages: 341-352
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22136001
[Journal Article] 膵癌の個別化医療分子生物学的解析を中心に2011
- Author(s)
  元井冬彦, 川口桂, 大峰健, 大槻純男, 大塚英郎, 他
- Journal Title
  
  外科
  
  Volume: 73巻 Pages: 1073-1078
- Data Source
  KAKENHI-PROJECT-21591766
[Journal Article] Reduction of LAT1 mRNA expression in brain capillaries in a mouse model of Parkinson's disease2010
- Author(s)
  Ohtsuki S
- Journal Title
  
  Biol.Pharm.Bull.
  
  Volume: 33(7) Pages: 1250-1252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] Involvement of multidrug resistance- associated protein 4 in efflux transport of prostaglandin E2 across mouse blood-brain barrier and its inhibition by intravenous administration of cephalosporins.2010
- Author(s)
  S. Akanuma, K. Hosoya, S. Ito, M. Tachikawa, T. Terasaki, S. Ohtsuki
- Journal Title
  
  J. Pharmacol. Exp. Ther 99
  
  Pages: 912-919
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] Atrial natriuretic peptide is eliminated from the brain by natriuretic peptide receptor-C-mediated brain-to-blood efflux transport at the blood-brain barrier2010
- Author(s)
  S. Ito, S. Ohtsuki, Y. Katsukura, M. Funaki, Y. Koitabashi, A. Sugino, S. Murata, T. Terasaki
- Journal Title
  
  J. Cereb. Blood Flow Metab.
  
  Volume: 31 Pages: 457-466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] 中枢への薬物分布におけるトランスポーターの機能と役割2009
- Author(s)
  大槻純男、寺崎哲也
- Journal Title
  
  日本薬理学雑誌 134
  
  Pages: 83-86
- NAID
  10025741265
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] 中枢への薬物分布におけるトランスポーターの機能と役割2009
- Author(s)
  大槻純男
- Journal Title
  
  日本薬理学雑誌 134
  
  Pages: 83-86
- NAID
  10025741265
- Data Source
  KAKENHI-PROJECT-19390038
[Journal Article] 中枢への薬物分布におけるトランスポーターの機能と役割2009
- Author(s)
  大槻純男
- Journal Title
  
  日本薬理学雑誌 134
  
  Pages: 83-86
- NAID
  10025741265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] Targeted Absolute Proteomicsを用いたトランスポーターの新しい研究展開2009
- Author(s)
  大槻純男、上家潤一、寺崎哲也
- Journal Title
  
  遺伝子医学MOOK12
  
  Pages: 48-54
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] Targeted Absolute Proteomics を用いたトランスポーターの新しい研究展開2009
- Author(s)
  大槻純男、寺崎哲也
- Journal Title
  
  遺伝子医学 12
  
  Pages: 48-54
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] 中枢への薬物分布におけるトランスポーターの機能と役割2009
- Author(s)
  大槻純男
- Journal Title
  
  日本薬理学雑誌 134
  
  Pages: 83-86
- NAID
  10025741265
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] 中枢への薬物分布におけるトランスポーターの機能と役割2009
- Author(s)
  大槻純男
- Journal Title
  
  日本薬理学雑誌
  
  Volume: 134 Pages: 83-86
- NAID
  10025741265
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] Targeted Absolute Proteomicsを用いたトランスポーターの新しい研究展開2009
- Author(s)
  大槻純男、上家潤一、寺崎哲也
- Journal Title
  
  遺伝子医学MOOK12
  
  Pages: 48-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] Targeted Absolute Proteomicsを用いたトランスポーターの新しい研究展開2009
- Author(s)
  大槻純男
- Journal Title
  
  遺伝子医学 12
  
  Pages: 48-54
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] mRNA expression levels of tight junction protein genes in mouse brain capillary endothelial cells highly purified by magnetic cell sorting2008
- Author(s)
  S. Ohtsuki, H. Yamaguchi, Y. Katsukura, T. Asashima, T. Terasaki
- Journal Title
  
  J. Neurochem 104
  
  Pages: 147-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] mRNA expression levels of tight junction protein genes in mouse brain capillary endothelial cells highly purified by magnetic cell sorting.2008
- Author(s)
  Sumio Ohtsuki
- Journal Title
  
  Journal of Neurochemistry 104
  
  Pages: 147-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390038
[Journal Article] Expression of nuclear receptor mRNA and liver X receptor-mediated regulation of ABC transporter A1 at rat blood-brain barrier.2008
- Author(s)
  Akanuma S, Hori S, Ohtsuki S, Fujiyoshi M, Terasaki T
- Journal Title
  
  Neurochem. Int 52
  
  Pages: 669-674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] Quantitative atlas of membrane transporter proteins: Development and application of a highly sensitive simultaneous LC/MS/MS method combined with novel in-silico peptide selection criteria.2008
- Author(s)
  Kamiie J, Ohtsuki S, Iwase R, Ohmine K, Katsukura Y, Yanai K, Sekine Y, Uchida Y, Ito S, Terasaki T
- Journal Title
  
  Pharm. Res 25
  
  Pages: 1469-1483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] 生体膜分子を基盤とする薬剤開発・治療に向けた新展開2008
- Author(s)
  大槻純男
- Journal Title
  
  薬学雑誌 128
  
  Pages: 495-496
- NAID
  110006656187
- Data Source
  KAKENHI-PROJECT-19390038
[Journal Article] mRNA expression levels of tight junction protein genes in mouse brain capillary endothelial cells highly purified by magnetic cell sorting.2008
- Author(s)
  S. Ohtsuki
- Journal Title
  
  J. Neurochem. 104
  
  Pages: 147-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] Quantitative atlas of membrane transporter proteins : Development and application of a highly sensitive simultaneous LC/MS/MS method combined with novel in-silico peptide selection criteria2008
- Author(s)
  J. Kamiie, S. Ohtsuki, R. Iwase, K. Ohmine, Y. Katsukura, K. Yanai, Y. Sekine, Y. Uchida, S. Ito, T. Terasaki
- Journal Title
  
  Pharm. Res.
  
  Volume: 25 Pages: 1469-1483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] mRNA expression levels of tight junction protein genes in mouse brain capillary endothelial cells highly purified by magnetic cell sorting.2008
- Author(s)
  S. Ohtsuki
- Journal Title
  
  J. Neurochem 104
  
  Pages: 147-154
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] 血液脳関門におけるモノアミン関連トランスポーターの役割2008
- Author(s)
  大槻純男
- Journal Title
  
  Clinical Neuroscience 26
  
  Pages: 1077-1080
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] mRNA expression levels of tight junction protein genes in mouse brain capillary endothelial cells highly purified by magnetic cell sorting2008
- Author(s)
  S. Ohtsuki, H. Yamaguchi, Y. Katsukura, T. Asashima, T. Terasaki
- Journal Title
  
  J. Neurochem.
  
  Volume: 104 Pages: 147-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] mRNA expression levels of tight junction protein genes in mouse brain capillary endothelial cells highly purified by magnetic cell sorting2008
- Author(s)
  S. Ohtsuki, H. Yamaguchi, Y. Katsukura, T. Asashima, T. Terasaki
- Journal Title
  
  J.Neurochem. 104
  
  Pages: 147-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390038
[Journal Article] mRNA expression levels of tight junction protein genes in mouse brain capillary endothelial cells highly purified by magnetic cell sorting.2008
- Author(s)
  Ohtsuki S, Yamaguchi H, Katsukura Y, Asashima T, Terasaki T
- Journal Title
  
  J. Neurochem 104
  
  Pages: 147-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] mRNA expression levels of tight junction protein genes in mouse brain capillary endothelial cells highly purified by magnetic cell sorting2008
- Author(s)
  S. Ohtsuki
- Journal Title
  
  J. Neurochem 104
  
  Pages: 147-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] Quantitative atlas of membrane transporter proteins : Development and application of a highly sensitive simultaneous LC/MS/MS method combined with novel in-silico peptide selection criteria2008
- Author(s)
  J. Kamiie, S. Ohtsuki, R. Iwase, K. Ohmine, Y. Katsukura, K. Yanai, Y. Sekine, Y. Uchida, S. Ito, T. Terasaki
- Journal Title
  
  Pharm. Res. 25
  
  Pages: 1469-1483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] 生体膜分子を基盤とする薬剤開発・治療に向けた新展開2008
- Author(s)
  大槻純男, 崔吉道
- Journal Title
  
  薬学雑誌 128
  
  Pages: 495-496
- NAID
  110006656187
- Data Source
  KAKENHI-PROJECT-19390038
[Journal Article] Expression of nuclear receptor mRNA and liver X receptor-mediated regulation of ABC transporter A1 at rat blood-brain barrier2008
- Author(s)
  S. Akanuma, S. Hori, S. Ohtsuki, M. Fujiyoshi, T. Terasaki
- Journal Title
  
  Neurochem. Int.
  
  Volume: 52 Pages: 669-674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] Quantitative atlas of membrane transporter proteins : Development and application of a highly sensitive simultaneous LC/MS/MS method combined with novel in-silico peptide selection criteria2008
- Author(s)
  J. Kamiie, S. Ohtsuki, R. Iwase, K. Ohmine, Y. Katsukura, K. Yanai, Y. Sekine, Y. Uchida, S. Ito, T. Terasaki
- Journal Title
  
  Pharm.Res. 25
  
  Pages: 1469-1483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390038
[Journal Article] Establishing a method to isolate rat brain capillary endothelial cells by magnetic cell sorting and dominant mRNA expression of multidrug resistance-associated protein 1 and 4 in highly purified rat brain capillary endothelial cells2007
- Author(s)
  . S. Ohtsuki, H. Yamaguchi, T. Asashima, T. Terasaki
- Journal Title
  
  Pharm. Res. 24
  
  Pages: 588-694
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] Establishing a method to isolate rat brain capillary endothelial cells by magnetic cell sorting and dominant mRNA expression of multidrug resistance-associated protein 1 and 4 in highly purified rat brain capillary endothelial cells2007
- Author(s)
  S. Ohtsuki, H. Yamaguchi, T. Asashima, T. Terasaki
- Journal Title
  
  Pharm. Res.
  
  Volume: 24 Pages: 588-694
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] Establishing a method to isolate rat brain capillary endothelial cells by magnetic cell sorting and dominant mRNA expression of multidrug resistance-associated protein 1 and 4 in highly purified rat brain capillary endothelial cells.2007
- Author(s)
  S. Ohtsuki
- Journal Title
  
  Pharm. Res. 24
  
  Pages: 688-694
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] Contribution of carrier-mediated transport systems to the blood-brain barrier as a supporting and protecting interface for the brain2007
- Author(s)
  S. Ohtsuki, T. Terasaki
- Journal Title
  
  Pharm. Res.
  
  Volume: 24 Pages: 1745-1758
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] Multichannel liquid chromatography. tandem mass spectrometry cocktail method for comprehensive substrate characterization of multidrug resistance-associated protein 4 transporter2007
- Author(s)
  Y. Uchida, J. Kamiie, S. Ohtsuki, T. Terasaki
- Journal Title
  
  Pharm. Res.
  
  Volume: 24 Pages: 2281-2296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] Contribution of carrier-mediated transport systems to the blood-brain barrier as a supporting and protecting interface for the brain; importance for CNS drug discoverv and development.2007
- Author(s)
  S. Ohtsuki
- Journal Title
  
  Pharm. Res. 24
  
  Pages: 1745-1757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] Correlation of induction of ATP binding cassette transporter A5 (ABCA5) and ABCB1 mRNAs with differentiation state of human colon tumor.2007
- Author(s)
  Ohtsuki S, Kamoi M, Watanabe Y, Suzuki H, Hori S, Terasaki T
- Journal Title
  
  Biol. Pharm. Bull 30
  
  Pages: 1144-1146
- NAID
  110006278407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] Brain-to-blood elimination of 24S-hydroxycholesterol from rat brain is mediated by organic anion transporting polypeptide 2 (oatp2) at the blood-brain barrier2007
- Author(s)
  S. Ohtsuki, S. Ito, A. Matsuda, S. Hori, T. Abe, T. Terasaki
- Journal Title
  
  J.Neurochem. 103
  
  Pages: 1430-1438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390038
[Journal Article] Contribution of carrier-mediated transport systems to the blood-brain barrier as a supporting and protecting interface for the brain; importance for CNS drug discovery and development.2007
- Author(s)
  S. Ohtsuki
- Journal Title
  
  Pharm. Res. 24
  
  Pages: 1745-1757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] Brain-to-blood elimination of 24S-hydroxy- cholesterol from rat brain is mediated by organic anion transporting polypeptide 2 (oatp2) at the blood-brain barrier.2007
- Author(s)
  Ohtsuki S, Ito S, Matsuda A, Hori S, Abe T, Terasaki T
- Journal Title
  
  J. Neurochem 103
  
  Pages: 1430-1438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] Establishing a method to isolate rat brain capillary endothelial cells by magnetic cell sorting and dominant mRNA expression of multidrug resistance-associated protein 1 and 4 in highly purified rat brain capillary endothelial cells.2007
- Author(s)
  Ohtsuki S, Yamaguchi H, Asashima T, Terasaki T
- Journal Title
  
  Pharm. Res 24
  
  Pages: 688-694
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] Brain-to-blood elimination of 24S-hydroxycholesterol from rat brain is mediated by organic anion transporting polypeptide 2(oatp2)at the blood-brain barrier2007
- Author(s)
  Sumio Ohtsuki
- Journal Title
  
  Journal of Neurochemistry 103
  
  Pages: 2482-2490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390038
[Journal Article] Multichannel liquid chromatography-tandem mass spectrometry cocktail method for comprehensive substrate characterization of multidrug resistance-associated protein 4 transporter2007
- Author(s)
  Y. Uchida, J. Kamiie, S. Ohtsuki, T. Terasaki
- Journal Title
  
  Pharm.Res. 24
  
  Pages: 2281-2296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390038
[Journal Article] Correlation of induction of ATP binding cassette transporter A5 (ABCA5) and ABCB1 mRNAs with differentiation state of human colon tumor.2007
- Author(s)
  S. Ohtsuki
- Journal Title
  
  Biol. Pharm. Bull. 30
  
  Pages: 1144-1146
- NAID
  110006278407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] 24S-Hydroxycholesterol induces cholesterol release from choroid plexus epithelial cells in an apical- and apoE isoform-dependent manner concomitantly with the induction of ABCA1 and ABCG1 expression.2007
- Author(s)
  Fujiyoshi M, Ohtsuki S, Hori S, Tachikawa M, Terasaki T
- Journal Title
  
  J. Neurochem 100
  
  Pages: 968-978
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] Brain-to-blood elimination of 24S-hydroxycholesterol from rat brain is mediated by organic anion transporting polypeptide 2 (oatp2) at the blood-brain barrier.2007
- Author(s)
  S. Ohtsuki
- Journal Title
  
  J. Neurochem. 103
  
  Pages: 1430-1438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] Contribution of carrier-mediated transport systems to the blood-brain barrier as a supporting and protecting interface for the brain ; importance for CNS drug discovery and development2007
- Author(s)
  S. Ohtsuki, T. Terasaki
- Journal Title
  
  Pharm. Res. 24
  
  Pages: 1745-1758
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] Establishing a method to isolate rat brain capillary endothelial cells by magnetic cell sorting and dominant mRNA expression of multidrug resistance-associated protein 1 and 4 in highly purified rat brain capillary endothelial cells.2007
- Author(s)
  S.Ohtsuki
- Journal Title
  
  Pharm. Res. 24
  
  Pages: 588-694
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] Hyperammonemia induces transport of taurine and creatine and suppresses claudin-12 gene expression in brain capillary endothelial cells in vitro.2007
- Author(s)
  M. Belanger, T. Asashima, S. Ohtsuki, H. Yamaguchi, S. Ito, T. Terasaki
- Journal Title
  
  Neurochem. Int 50
  
  Pages: 95-101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] Multichannel liquid chromatography-tandem mass spectrometry cocktail method for comprehensive substrate characterization of multidrug resistance-associated protein 4 transporter2007
- Author(s)
  Y. Uchida, J. Kamiie, S. Ohtsuki, T. Terasaki
- Journal Title
  
  Pharm. Res. 24
  
  Pages: 2281-2296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] Multichannel Liquid chromatography-tandem mass spectrometry cocktail method for comprehensive substrate characterization of multidrug resistance-associated protein 4 transporter.2007
- Author(s)
  Uchida Y, Kamiie J, Ohtsuki S, Terasaki T
- Journal Title
  
  Pharm. Res 24
  
  Pages: 2281-2296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] Modulation and compensation of the mRNA expression of energy related transporters in the brain of glucose transporter 1-deficient mice.2006
- Author(s)
  Ohtsuki S, Kikkawa T, Hori S, Terasaki T
- Journal Title
  
  Biol. Pharm. Bull 29
  
  Pages: 1587-1591
- NAID
  110005663994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] 脳関門輸送の分子機構と脳へのDDS2006
- Author(s)
  大槻純男
- Journal Title
  
  DDS学会誌 21
  
  Pages: 102-110
- NAID
  10018118754
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390037
[Journal Article] 脳関門輸送の分子機構と脳へのDDS2006
- Author(s)
  大槻純男
- Journal Title
  
  DDS学会誌 21
  
  Pages: 102-110
- NAID
  10018118754
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] Modulation and compensation of the mRNA expression of energy related transporters in the brain of glucose transporter 1-deficient mice.2006
- Author(s)
  S.Ohtsuki
- Journal Title
  
  Biol. Pharm. Bull. 29
  
  Pages: 1587-1591
- NAID
  110005663994
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] Molecular mechanisms of the blood-brain barrier transport and DDS to the brain.2006
- Author(s)
  Sumio Ohtsuki
- Journal Title
  
  Drug Delivery System 21
  
  Pages: 102-110
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390037
[Journal Article] Major involvement of low-density lipoprotein receptor- related protein 1 in the clearance of plasma free amyloid beta-peptide by the liver.2006
- Author(s)
  Tamaki C., Ohtsuki S, Iwatsubo T, Hashimoto T, Yamada K, Yabuki C, Terasaki T
- Journal Title
  
  Pharm Res 23
  
  Pages: 1407-1416
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] ATP-binding cassette transporter G2 mediates the efflux of phototoxins on the luminal membrane of retinal capillary endothelial cells.2006
- Author(s)
  Asashima T, Hori S, Ohtsuki S, Tachikawa M, Watanabe M, Mukai C, Kitagaki S, Miyakoshi N, Terasaki T
- Journal Title
  
  Pharm Res 23
  
  Pages: 1235-1242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] Vascular endothelium-selective gene induction by Tie2 promoter/enhancer in the brain and retina of a transgenic rat.2005
- Author(s)
  S.Ohtsuki
- Journal Title
  
  Pharm. Res. 22
  
  Pages: 852-857
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] Dominant expression of androgen receptors and their functional regulation of organic anion transporter 3 in rat brain capillary endothelial cells ; comparison of gene expression between the blood-brain and -retinal barriers.2005
- Author(s)
  S.Ohtsuki
- Journal Title
  
  J.Cell.Physiol. 204
  
  Pages: 896-900
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] Distinct spatio-temporal expression of ABCA and ABCG transporters in the developing and adult mouse brain.2005
- Author(s)
  Tachikawa M, Watanabe M, Hori S, Fukaya M, Ohtsuki S, Asashima T, Terasaki T
- Journal Title
  
  J Neurochem 95
  
  Pages: 294-304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081002
[Journal Article] 脳を守る血液脳関門の輸送機構2005
- Author(s)
  大槻純男
- Journal Title
  
  CYRICニュース 37
  
  Pages: 4-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390037
[Journal Article] Dominant expression of androgen receptors and their functional regulation of organic anion transporter 3 in rat brain capillary endothelial cells; comparison of gene expression between the blood-brain and -retinal barriers.2005
- Author(s)
  S.Ohtsuki
- Journal Title
  
  J. Cell. Physiol. 204
  
  Pages: 896-900
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] Dominant expression of androgen receptors and their functional regulation of organic anion transporter 3 in rat brain capillary endothelial cells ; comparison of gene expression between the blood-brain and -retinal barriers.2005
- Author(s)
  Sumio Ohtsuki
- Journal Title
  
  J.Cell.Physiol. 204
  
  Pages: 896-900
- Data Source
  KAKENHI-PROJECT-16390037
[Journal Article] Vascular endothelium-selective gene induction by Tie2 promoter/enhancer in the brain and retina of a transgenic rat.2005
- Author(s)
  S.Ohtsuki
- Journal Title
  
  Pharm.Res. 22
  
  Pages: 852-857
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] Dominant expression of androgen receptors and their functional regulation of organic anion transporter 3 in rat brain capill ary endothelial cells ; comparison of gene expression between the blood-brain and-retinal barriers.2005
- Author(s)
  Sumio Ohtsuki
- Journal Title
  
  J.Cell.Physiol. 204
  
  Pages: 896-900
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390037
[Journal Article] Transport system at the blood-brain barrier to protect brain functions.2005
- Author(s)
  Sumio Ohtsuki
- Journal Title
  
  CYRIC News 37
  
  Pages: 4-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390037
[Journal Article] Dominant expression of androgen receptors and their functional regulation of organic anion transporter 3 in rat brain capillary endothelial cells; comparison of gene expression between the blood-brain and -retinal barriers.2005
- Author(s)
  Sumio Ohtsuki
- Journal Title
  
  Journal of Cellular Physiology 204
  
  Pages: 896-900
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390037
[Journal Article] mRNA expression of the ATP-binding cassette transporter subfamily A (ABCA) in rat and human brain capillary endothelial cells.2004
- Author(s)
  Sumio Ohtsuki
- Journal Title
  
  Biol.Pharm.Bull. 27
  
  Pages: 1437-1440
- NAID
  110003608990
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390037
[Journal Article] Localization of organic anion transporting polypepetide 3(oatp3) in mouse brain parenchymal and capillary endothelial cells.2004
- Author(s)
  S.Ohtsuki
- Journal Title
  
  J.Neurochem. 90
  
  Pages: 743-749
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] Application of the blood brain barrier transport as a dynamic transport system.2004
- Author(s)
  S.Ohtsuki
- Journal Title
  
  Monthly Yakuji 46
  
  Pages: 1243-1249
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] Localization of organic anion transporting polypeptide 3 (oatp3) in mouse brain parenchymal and capillary endothelial cells.2004
- Author(s)
  Sumio Ohtsuki
- Journal Title
  
  J.Neurochem. 90
  
  Pages: 743-749
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390037
[Journal Article] Localization of organic anion transporting polypepetide 3 (oatp3) in mouse brain parenchymal and capillary endothelial cells.2004
- Author(s)
  S.Ohtsuki
- Journal Title
  
  J. Neurochem. 90
  
  Pages: 743-749
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] New aspects of the blood brain barrier transporters ; its physiological roles in the central nervous system.2004
- Author(s)
  S.Ohtsuki
- Journal Title
  
  Biological & Pharmaceutical Bulletin 27
  
  Pages: 1489-1496
- NAID
  110003608642
- Data Source
  KAKENHI-PROJECT-16390037
[Journal Article] New aspects of the blood brain barrier transporters; its physiological roles in the central nervous system.2004
- Author(s)
  Sumio Ohtsuki
- Journal Title
  
  Biological ＆ Pharmaceutical Bulletin 27
  
  Pages: 1489-1496
- NAID
  110003608642
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390037
[Journal Article] New aspects of the blood brain barrier transporters; its physiological roles in the central nervous system.2004
- Author(s)
  Sumio Ohtsuki
- Journal Title
  
  Biol.Pharm.Bull. 27
  
  Pages: 1489-1496
- NAID
  110003608642
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390037
[Journal Article] 中枢支援防御システムとしての血液脳関門輸送の生理機能2004
- Author(s)
  大槻純男
- Journal Title
  
  薬学雑誌 24
  
  Pages: 791-802
- NAID
  110003666135
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390037
[Journal Article] Mouse "reduced in osteosclerosis" transporter (Roct) functions as an organic anion transporter 3 (mOAT3) and is localized at abluminal membrane of blood-brain barrier.2004
- Author(s)
  S.Ohtsuki
- Journal Title
  
  J. Pharmacol. Exp. Ther. 309
  
  Pages: 1273-1281
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] mRNA expression of the ATP-binding cassette transporter subfamily A (ABCA) in rat and human brain capillary endothelial cells.2004
- Author(s)
  S.Ohtsuki et al.
- Journal Title
  
  Biological & Pharmaceutical Bulletin 27
  
  Pages: 1437-1440
- NAID
  110003608990
- Data Source
  KAKENHI-PROJECT-16390037
[Journal Article] Localization of organic anion transporting polypeptide 3 (oatp3) in mouse brain parenchymal and capillary endothelial cells.2004
- Author(s)
  S.Ohtsuki et al.
- Journal Title
  
  Journal of Neurochemistry 90
  
  Pages: 743-749
- Data Source
  KAKENHI-PROJECT-16390037
[Journal Article] Mouse "reduced in osteosclerosis" transporter (Roct) functions as an organic anion transporter 3(mOAT3) and is localized at abluminal membrane of blood-brain barrier.2004
- Author(s)
  S.Ohtsuki
- Journal Title
  
  J.Pharmacol.Exp.Ther. 309
  
  Pages: 1273-1281
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] mRNA expression of the ATP-binding cassette transporter subfamily A (ABCA) in rat and human brain capillary endothelial cells.2004
- Author(s)
  Sumio Ohtsuki
- Journal Title
  
  Biological ＆ Pharmaceutical Bulletin 27
  
  Pages: 1437-1440
- NAID
  110003608990
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390037
[Journal Article] Localization of organic anion transporting polypepetide 3 (oatp3) in mouse brain parenchymal and capillary endothelial cells.2004
- Author(s)
  S.Ohtsuki
- Journal Title
  
  J.Neurochem. 90
  
  Pages: 743-749
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] mRNA expression of the ATP-binding cassette transporter subfamily A (ABCA) in rat and human brain capillary endothelial cells.2004
- Author(s)
  S.Ohtsuki
- Journal Title
  
  Biol. Pharm. Bull. 27
  
  Pages: 1437-1440
- NAID
  110003608990
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] Mouse "reduced in osteosclerosis" transporter (Roct) functions as an organic anion transporter 3 (mOAT3) and is localized at abluminal membrane of blood-brain barrier.2004
- Author(s)
  S.Ohtsuki
- Journal Title
  
  J.Pharmacol.Exp.Ther. 309
  
  Pages: 1273-1281
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] mRNA expression of the ATP-binding cassette transporter subfamily A (ABCA) in rat and human brain capillary endothelial cells.2004
- Author(s)
  S.Ohtsuki
- Journal Title
  
  Biol.Pharm.Bull. 27
  
  Pages: 1437-1440
- NAID
  110003608990
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] Localization of organic anion transporting polypeptide 3 (oatp3) in mouse brain parenchymal and capillary endothelial cells.2004
- Author(s)
  Sumio Ohtsuki
- Journal Title
  
  Journal of Neurochemistry 90
  
  Pages: 743-749
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390037
[Journal Article] ダイナミック輸送システムとしての血液脳関門と中枢創薬研究への応用2004
- Author(s)
  大槻純男
- Journal Title
  
  月刊薬事 46
  
  Pages: 1243-1249
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] Physiological roles of the blood-brain barrier transport system as CN S supporting and protecting system.2004
- Author(s)
  Sumio Ohtsuki
- Journal Title
  
  Yakugaku Zasshi 24
  
  Pages: 791-802
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390037
[Journal Article] mRNA expression of the ATP-binding cassette transporter subfamily A(ABCA) in rat and human brain capillary endothelial cells.2004
- Author(s)
  S.Ohtsuki
- Journal Title
  
  Biol.Pharm.Bull. 27
  
  Pages: 1437-1440
- NAID
  110003608990
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] 血液脳関門の分子生理2003
- Author(s)
  大槻純男
- Journal Title
  
  ファルマシア 39
  
  Pages: 1057-1061
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] In vitro study on the functional expression of organic anion transporting polypeptide 3 at rat choloid plexus epithelial cells and its involvement in the cerebrospinal fluid-to-blood-transport of estrone-3-sulfate.2003
- Author(s)
  S.Ohtsuki
- Journal Title
  
  Mol.Pharmacol. 63
  
  Pages: 532-537
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] 血液脳関門におけるセロトニントランスポーター2003
- Author(s)
  大槻純男
- Journal Title
  
  Clinical Neuroscience 21(6)
  
  Pages: 641-643
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] The blood-brain barrier protecting the brain.2003
- Author(s)
  S.Ohtsuki
- Journal Title
  
  Future materials 3
  
  Pages: 2-6
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] Serotonin transporter at the blood-brain barrier.2003
- Author(s)
  S.Ohtsuki
- Journal Title
  
  Clinical neuroscience 21(6)
  
  Pages: 641-643
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] Molecular mechanism in the drug permeation and efflux at the blood-brain barrier.2003
- Author(s)
  S.Ohtsuki
- Journal Title
  
  Folia Pharmacoligica Japonica 122
  
  Pages: 55-64
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] Molecular physiology of the blood-brain barrier.2003
- Author(s)
  S.Ohtsuki
- Journal Title
  
  Farumashia 39
  
  Pages: 1057-1061
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] In vitro study on the functional expression of organic anion transporting polypeptide 3 at rat choloid plexus epithelial cells and its involvement in the cerebrospinal fluid-to-blood-transport of estrone-3-sulfate.2003
- Author(s)
  S.Ohtsuki
- Journal Title
  
  Mol. Pharmacol. 63
  
  Pages: 532-537
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] 脳を守る脳関門トランスポーター2003
- Author(s)
  大槻純男
- Journal Title
  
  未来材料(Review視点-護る) 3
  
  Pages: 2-6
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] 血液脳関門の薬物透過と排出の分子機構〜中枢支援防御システム〜2003
- Author(s)
  大槻純男
- Journal Title
  
  日本薬理学雑誌 122
  
  Pages: 55-64
- NAID
  130000085998
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] Physiological roles of the blood-brain barrier transport as the CNS supporting and protecting system.2002
- Author(s)
  S.Ohtsuki
- Journal Title
  
  Basics and clinics in neuroscience Vol 11
  
  Pages: 23-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] Role of blood-brain barrier organic anion transporter 3 (OAT3) in the efflux of indoxyl sulfate, a uremic toxin : Its involvement in neurotransmitter metabolite clearance from the brain.2002
- Author(s)
  S.Ohtsuki
- Journal Title
  
  J. Neurochem. 83
  
  Pages: 57-66
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] The blood-brain barrier creatine transporter is a major pathway for supplying creatine to the brain.2002
- Author(s)
  S.Ohtsuki
- Journal Title
  
  J.Cereb.Blood Flow Metab. 22
  
  Pages: 1327-1335
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] Role of blood-brain barrier organic anion transporter 3 (OATS) in the efflux of indoxyl sulfate, a uremic toxin : Its involvement in neurotransmitter metabolite clearance from the brain.2002
- Author(s)
  S.Ohtsuki
- Journal Title
  
  J.Neurochem. 83
  
  Pages: 57-66
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Journal Article] The blood-brain barrier creatine transporter is a major pathway for supplying creatine to the brain.2002
- Author(s)
  S.Ohtsuki
- Journal Title
  
  J. Cereb. Blood Flow Metab. 22
  
  Pages: 1327-1335
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207104
[Patent] 血液脳関門透過性ペプチド2019
- Inventor(s)
  19.伊藤慎悟、大槻純男、山口駿介
- Industrial Property Rights Holder
  19.伊藤慎悟、大槻純男、山口駿介
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-18H02590
[Patent] 血液脳関門透過性ペプチド2018
- Inventor(s)
  伊藤慎悟、大槻純男、山口駿介
- Industrial Property Rights Holder
  伊藤慎悟、大槻純男、山口駿介
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-134042
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18H02590
[Patent] 膠芽腫マーカー及びその使用2017
- Inventor(s)
  中田光俊，寺崎哲也、大槻純男
- Industrial Property Rights Holder
  中田光俊，寺崎哲也、大槻純男
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-233838
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16K15645
[Patent] 新規な細胞膜透過性ペプチド2017
- Inventor(s)
  伊藤慎悟、大槻純男
- Industrial Property Rights Holder
  伊藤慎悟、大槻純男
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Overseas
- Data Source
  KAKENHI-PROJECT-16K15162
[Patent] 新規な細胞膜透過性ペプチド2016
- Inventor(s)
  伊藤慎悟、大槻純男
- Industrial Property Rights Holder
  熊本大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016-05-18
- Overseas
- Data Source
  KAKENHI-PROJECT-16K15162
[Patent] 質量分析におけるペプチドピークの同定・定量のためのデータベース作成方法2014
- Inventor(s)
  大槻純男
- Industrial Property Rights Holder
  大槻純男
- Industrial Property Rights Type
  特許
- Filing Date
  2014-07-07
- Overseas
- Data Source
  KAKENHI-PROJECT-26640092
[Patent] 質量分析計を使った膜タンパク質の定量方法2011
- Inventor(s)
  上家潤一、大槻純男、寺崎哲也
- Industrial Property Rights Holder
  国立大学法人東北大学
- Filing Date
  2011-03-08
- Overseas
- Data Source
  KAKENHI-PROJECT-18109002
[Patent] 質量分析計を使った膜タンパク質の定量方法2011
- Inventor(s)
  上家潤一、大槻純男、寺崎哲也
- Industrial Property Rights Holder
  国立大学法人東北大学
- Filing Date
  2011-01-28
- Data Source
  KAKENHI-PROJECT-18109002
[Patent] 質量分析計を使った膜タンパク質の定量方法2010
- Inventor(s)
  上家潤一、大槻純男、寺崎哲也
- Industrial Property Rights Holder
  国立大学法人東北大学
- Filing Date
  2010-10-07
- Overseas
- Data Source
  KAKENHI-PROJECT-18109002
[Patent] 質量分析計を使った膜タンパク質の定量方法2008
- Inventor(s)
  上家潤一、大槻純男、寺崎哲也
- Industrial Property Rights Holder
  国立大学法人東北大学
- Filing Date
  2008-05-22
- Overseas
- Data Source
  KAKENHI-PROJECT-18109002
[Patent] 質量分析計を使った膜タンパク質の定量方法2008
- Inventor(s)
  上家潤三大槻純男寺崎哲也
- Industrial Property Rights Holder
  東北大学
- Filing Date
  2008-05-16
- Overseas
- Data Source
  KAKENHI-PROJECT-18109002
[Patent] 質量分析計を使った膜タンパク質の定量方法2008
- Inventor(s)
  上家潤一大槻純男寺崎哲也
- Industrial Property Rights Holder
  東北大学
- Filing Date
  2008-05-08
- Overseas
- Data Source
  KAKENHI-PROJECT-18109002
[Patent] 質量分析計を使った膜タンパク質の定量方法2008
- Inventor(s)
  上家潤一、大槻純男、寺崎哲也
- Industrial Property Rights Holder
  国立大学法人東北大学
- Filing Date
  2008-05-16
- Overseas
- Data Source
  KAKENHI-PROJECT-18109002
[Patent] 質量分析計を使った膜タンパク質の定量方法2008
- Inventor(s)
  上家潤一、大槻純男、寺崎哲也
- Industrial Property Rights Holder
  国立大学法人東北大学
- Filing Date
  2008-06-17
- Overseas
- Data Source
  KAKENHI-PROJECT-18109002
[Patent] 質量分析計を使った膜タンパク質の定量方法2008
- Inventor(s)
  上家潤一、大槻純男、寺崎哲也
- Industrial Property Rights Holder
  国立大学法人東北大学
- Filing Date
  2008-05-08
- Overseas
- Data Source
  KAKENHI-PROJECT-18109002
[Patent] 質量分析計を使った膜タンパク質の定量方法2008
- Inventor(s)
  上家潤一大槻純男寺崎哲也
- Industrial Property Rights Holder
  東北大学
- Filing Date
  2008-06-17
- Overseas
- Data Source
  KAKENHI-PROJECT-18109002
[Patent] 質量分析計を使った膜タンパク質の定量方法2008
- Inventor(s)
  上家潤三大槻純男寺崎哲也
- Industrial Property Rights Holder
  東北大学
- Filing Date
  2008-05-08
- Overseas
- Data Source
  KAKENHI-PROJECT-18109002
[Patent] 質量分析計を使った膜タンパク質の定量方法2008
- Inventor(s)
  上家潤一大槻純男寺崎哲也
- Industrial Property Rights Holder
  東北大学
- Filing Date
  2008-05-22
- Overseas
- Data Source
  KAKENHI-PROJECT-18109002
[Patent] 質量分析計を使った膜タンパク質の定量方法2008
- Inventor(s)
  上家潤一、大槻純男、寺崎哲也
- Industrial Property Rights Holder
  国立大学法人東北大学
- Filing Date
  2008-05-08
- Overseas
- Data Source
  KAKENHI-PROJECT-18109002
[Patent] 質量分析計を使った膜タンパク質の定量方法2008
- Inventor(s)
  上家潤一大槻純男寺崎哲也
- Industrial Property Rights Holder
  東北大学
- Filing Date
  2008-05-06
- Overseas
- Data Source
  KAKENHI-PROJECT-18109002
[Patent] 質量分析計を使った膜タンパク質の定量方法2008
- Inventor(s)
  上家潤一、大槻純男、寺崎哲也
- Industrial Property Rights Holder
  国立大学法人東北大学
- Filing Date
  2008-05-06
- Overseas
- Data Source
  KAKENHI-PROJECT-18109002
[Presentation] Identification of cell-surface proteins internalized into in vitro human brain microvascular endothelial cells by SWATH-based quantitative proteomics.2019
- Author(s)
  Shingo Ito, Mariko Oishi, Tatsuki Uemura, Takeshi Masuda, Tomomi Furihata, Pierre-Olivier Couraud, Sumio Ohtsuki
- Organizer
  BBB signaling 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02590
[Presentation] Cyclic peptides facilitating BBB permeability of macromolecules.2019
- Author(s)
  Sumio Ohtsuki
- Organizer
  1st Mini-Symposium on the Blood Brain Barrier
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02590
[Presentation] オミクスの網羅的・定量的解析によって拓かれる創薬・動態研究2019
- Author(s)
  大槻純男
- Organizer
  薬物動態談話会 1月例会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02590
[Presentation] Identification of cyclic peptide facilitating permeability of M13 phage across the blood-brain barrier,2019
- Author(s)
  Shunsuke Yamaguchi, Shingo Ito, Takeshi Masuda, Sumio Ohtsuki
- Organizer
  2019 Cerebral Vascular Biology Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02590
[Presentation] 高分子を脳実質へ送達する血液脳関門透過性環状ペプチドの同定2019
- Author(s)
  山口駿介、伊藤慎悟、増田豪、大槻純男
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18H02590
[Presentation] ミクログリアの細胞表面に発現するアルツハイマー病危険因子CD33のリガンドの同定2019
- Author(s)
  太田千晴、於久祐己、堀祐真、長井京介、増田豪、大槻純男、長田重一、城谷圭朗、岩田修永
- Organizer
  第36回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-18K06787
[Presentation] Identification of novel internalized cell surface proteins in human brain capillary endothelial cells by SWATH-MS2018
- Author(s)
  Shingo Ito, Mariko Oishi, Takeshi Masuda, Tomomi Furihata, Sumio Ohtsuki
- Organizer
  SFN2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02590
[Presentation] 環状ペプチドによる小腸透過キャリアの開発2018
- Author(s)
  大槻純男、増田豪、伊藤慎悟
- Organizer
  立命館大学創剤研究コンソーシアム2017年度第2回研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16K15162
[Presentation] インスリン抵抗性マウスにおける脳関門および脳実質のタンパク質発現および機能変動の解明2018
- Author(s)
  緒方星陵、伊藤慎悟、増田豪、大槻純男
- Organizer
  創剤フォーラム第24回若手研究会
- Data Source
  KAKENHI-PROJECT-18H02590
[Presentation] 定量プロテオミクスを活用した脳血管研究2018
- Author(s)
  大槻純男
- Organizer
  第2回九州血管の会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02590
[Presentation] 脳内への高分子送達に資する新規BBB透過性環状ペプチドの同定2018
- Author(s)
  山口駿介、伊藤慎悟、増田豪、大槻純男
- Organizer
  第12回次世代を担う若手医療薬科学シンポジウム
- Data Source
  KAKENHI-PROJECT-18H02590
[Presentation] Identification of internalized plasma membrane proteins in human brain capillary endothelial cells.2018
- Author(s)
  Mariko Oishi, Shingo Ito, Takeshi Masuda, Tomomi Furihata, Sumio Ohtsuki
- Organizer
  Mass Spec and Proteomics 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02590
[Presentation] Comprehensive identification of internalized membrane proteins in human brain capillary endothelial cells.2018
- Author(s)
  Mariko Oishi, Shingo Ito, Takeshi Masuda, Tomomi Furihata, Sumio Ohtsuki
- Organizer
  The 2nd Workshop for Korea-Japan Young Scientists on Pharmaceutics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02590
[Presentation] Membrane enrichment for targeted proteomics of enzymes and transporters in different tissues and cell lines.2018
- Author(s)
  Sumio Ohtsuki
- Organizer
  ISSX Workshop on LC-MS Proteomics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02590
[Presentation] 高分子医薬品の脳内送達に資する血液脳関門透過性環状ペプチドの同定2018
- Author(s)
  山口駿介、伊藤慎悟、増田豪、大槻純男
- Organizer
  第1回超分子薬剤学FGシンポジウム
- Data Source
  KAKENHI-PROJECT-18H02590
[Presentation] 患者由来iPS細胞を利用したアルツハイマー病のサブタイプ特異的バイオマーカーの探索2017
- Author(s)
  岩田修永、松尾和哉、大槻純男、浅井　将、近藤孝之、井上治久、城谷圭朗
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  ブリックホール（長崎県・長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-26460200
[Presentation] トランスオミクスによるSLC22A18の生理機能の解明2017
- Author(s)
  伊藤慎悟、本多玄太郎、赤澤貴憲、寺崎哲也、大槻純男
- Organizer
  第10回トランスポーター研究会九州部会
- Data Source
  KAKENHI-PROJECT-16K08373
[Presentation] トランスオミクスによるオーファントランスポーターSLC22A18の生理機能解明2017
- Author(s)
  伊藤慎悟、本多玄太郎、赤澤貴憲、寺崎哲也、大槻純男
- Organizer
  第41回蛋白質と酵素の構造と機能に関する九州シンポジウム
- Data Source
  KAKENHI-PROJECT-16K08373
[Presentation] オーファントランスポーターSLC22A18のタンパク質翻訳後修飾への関与2017
- Author(s)
  伊藤慎悟、本多玄太郎、赤澤貴憲、寺崎哲也、大槻純男
- Organizer
  日本プロテオーム学会2017
- Data Source
  KAKENHI-PROJECT-16K08373
[Presentation] 経口投与型高分子医薬品の開発を目指した小腸透過性環状ペプチドの同定と評価2017
- Author(s)
  原田智徳、山口駿介、増田豪、伊藤慎悟、大槻純男
- Organizer
  第41回蛋白質と酵素の構造と機能に関する九州シンポジウム
- Data Source
  KAKENHI-PROJECT-16K15162
[Presentation] 高分子医薬品の小腸透過を改善させる小腸透過性環状ペプチドの同定2016
- Author(s)
  山口駿介、伊藤慎悟、平山未央、大槻純男
- Organizer
  第32回DDS学会
- Place of Presentation
  静岡
- Year and Date
  2016-06-30
- Data Source
  KAKENHI-PROJECT-16K15162
[Presentation] 脳クレアチン欠乏症候群に関連する新規変異クレアチントランスポーターのクレアチン輸送活性低下とそのメカニズムの解明2016
- Author(s)
  上村立記、伊藤慎悟、太田悠介、立川正憲、平山未央、和田敬仁、寺崎哲也、大槻純男
- Organizer
  第40回　蛋白質と酵素の構造と機能に関する九州シンポジウム
- Place of Presentation
  鹿児島
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-26293035
[Presentation] アルツハイマー病サブグループのバイオマーカーの探索2016
- Author(s)
  松尾和哉、大槻純男、浅井将、城谷圭朗、近藤孝之、井上治久、岩田修永
- Organizer
  第33回日本薬学会九州支部大会
- Place of Presentation
  鹿児島大学(鹿児島県・鹿児島市）
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-26460200
[Presentation] Identification of Novel Cyclic Peptides for Facilitating Intestinal Permeability of Macromolecule2016
- Author(s)
  Shunsuke Yamaguchi, Shingo Ito, Mio Hirayama, Sumio Ohtsuki
- Organizer
  2016 AAPS Annual Meeting and Exposition
- Place of Presentation
  Debver, USA
- Year and Date
  2016-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15162
[Presentation] 患者由来iPS細胞を利用したアルツハイマー病のバイオマーカーの探索2016
- Author(s)
  岩田修永、松尾和哉、大槻純男、浅井将、近藤孝之、井上治久、城谷圭朗
- Organizer
  第35回日本認知症学会学術集会
- Place of Presentation
  東京国際フォーラム（東京都・千代田区）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-26460200
[Presentation] 経口投与型DDS開発を目指した小腸透過性環状ペプチドの同定とin vivo有効性評価2016
- Author(s)
  伊藤慎悟、大槻純男
- Organizer
  第39回薬物動態懇談会
- Place of Presentation
  浜松
- Year and Date
  2016-11-10
- Invited
- Data Source
  KAKENHI-PROJECT-16K15162
[Presentation] Targeted proteomic approach to cancer biomarkers and diagnosis2016
- Author(s)
  Sumio Ohtsuki
- Organizer
  Japna-US Workshop for Early Cancer Research: Biomarker Discovery for Early Cancer Detection
- Place of Presentation
  東京
- Year and Date
  2016-03-07
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26640092
[Presentation] アルツハイマー病サブグループのバイオマーカーの探索2016
- Author(s)
  松尾和哉、吉崎涼平、大槻純男、浅井将、城谷圭朗、近藤孝之、井上治久、岩田修永
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センタ―他(宮城県・仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26460200
[Presentation] 経口投与型バイオ医薬品の開発に資する小腸透過性環状ペプチドの同定2016
- Author(s)
  山口駿介、伊藤慎悟、平山未央、大槻純男
- Organizer
  第33回日本薬学会九州支部大会
- Place of Presentation
  鹿児島
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-16K15162
[Presentation] Development of biomarkers specific for Alzheimer's disease subgroups2016
- Author(s)
  Matsuo K, Ohtsuki S, Asai M, Shirotani K, Kondo T, Inoue H, and Iwata N
- Organizer
  The 8th Takeda Science Foundation Symposium on PharmaSciences
- Place of Presentation
  武田薬品研修所（大阪府・吹田市）
- Year and Date
  2016-01-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460200
[Presentation] SLC22A18 is involved in the proliferation of MCF-7 human breast cancer cells by altering cellular protein expression2016
- Author(s)
  Shingo Ito, Yu Fujino, Sumio Ohtsuki
- Organizer
  Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
- Place of Presentation
  Kumamoto, Japan
- Year and Date
  2016-10-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08373
[Presentation] Biomarkers of glioblastoma identified by quantitative proteomics with SWATH mass spectrometry2016
- Author(s)
  Nakada M, Miyauchi E, Tachikawa M, Furuta T, Sabit H, Ohtsuki S, Terasaki T.
- Organizer
  The 21st International Conference on Brain Tumor Research & Therapy
- Place of Presentation
  Okinawa, Bankoku Shinryokan
- Year and Date
  2016-04-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15645
[Presentation] 新規変異クレアチントランスポーターのクレアチン輸送活性低下とそのメカニズムの解明2016
- Author(s)
  上村立記、伊藤慎悟、太田悠介、立川正憲、黒木未央、和田敬仁、寺崎哲也、大槻純男
- Organizer
  第9回トランスポーター研究会九州部会
- Place of Presentation
  宮崎
- Data Source
  KAKENHI-PROJECT-26293035
[Presentation] 脳クレアチン欠乏症候群に関連する新規変異クレアチントランスポーターの発現・局在と輸送機能特性の解析2015
- Author(s)
  上村立記、伊藤慎悟、太田悠介、立川正憲、平山未央、和田敬仁、寺崎哲也、大槻純男
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-26461544
[Presentation] 疾患iPS細胞を用いたアルツハイマー病サブタイプ特異的バイオマーカーの探索2015
- Author(s)
  松尾和哉、大槻純男、浅井将、城谷圭朗、近藤孝之、井上治久、岩田修永
- Organizer
  平成27年度日本生化学会九州支部例会
- Place of Presentation
  九州大学箱崎キャンパス（福岡県・福岡市）
- Year and Date
  2015-05-16
- Data Source
  KAKENHI-PROJECT-26460200
[Presentation] 定量的標的プロテオミクスを活用したがんバイオマーカー研究2015
- Author(s)
  大槻純男
- Organizer
  第22回HAB研究機構学術年会
- Place of Presentation
  東京
- Year and Date
  2015-06-26
- Invited
- Data Source
  KAKENHI-PROJECT-26640092
[Presentation] 質量分析でタンパク質を測ると何が見えるか2015
- Author(s)
  大槻純男
- Organizer
  第40回西日本薬剤学研究会
- Place of Presentation
  九重
- Year and Date
  2015-08-21
- Invited
- Data Source
  KAKENHI-PROJECT-26640092
[Presentation] Molecular genetic study and urine analysis of Japanese patients with cerebral creatine deficiency syndromes.2015
- Author(s)
  H. Shimbo, H. Osaka, M. Tachikawa, S. Ohtsuki, S. Ito, T. Goto, Y. Tsuyusaki, N. Aida, K. Kurosawa, Y. Kurosawa, H. Kato, K. Takano, T. Wada.
- Organizer
  65th American Society of Human Genetics
- Place of Presentation
  Baltimore
- Year and Date
  2015-10-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461544
[Presentation] Changes of cellular localization and transport activity by a novel mutation in creatine transporter associated with chronic cerebral creatine depletion2015
- Author(s)
  Tatsuki Uemura, Shingo Ito, Yusuke Ota, Masanori Tachikawa, Takahito Wada, Mio Hirayama, Tetsuya Terasaki, Sumio Ohtsuki
- Organizer
  International Symposium on Chronic Inflammatory Diseases
- Place of Presentation
  Kumamoto
- Year and Date
  2015-10-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461544
[Presentation] 基礎と臨床をつなぐ次世代プロテオミクス2015
- Author(s)
  大槻純男
- Organizer
  第1回川島カンファレンス
- Place of Presentation
  岐阜
- Year and Date
  2015-11-14
- Invited
- Data Source
  KAKENHI-PROJECT-26640092
[Presentation] 「脳クレアチン欠乏症候群の臨床研究班」の取り組み2015
- Author(s)
  和田敬仁，小坂仁，相田典子，後藤知英，露崎悠，新保裕子，加藤秀一，高野亨子，大槻純男，伊藤慎悟，立川正憲，黒澤裕子
- Organizer
  第57回日本小児神経学会
- Place of Presentation
  大阪
- Year and Date
  2015-05-27
- Data Source
  KAKENHI-PROJECT-26461544
[Presentation] 生命科学・薬物動態研究者による定量プロテオミクス開発と応用2015
- Author(s)
  大槻純男
- Organizer
  BMAS2015
- Place of Presentation
  長崎
- Year and Date
  2015-08-22
- Invited
- Data Source
  KAKENHI-PROJECT-26640092
[Presentation] 新規変異クレアチントランスポーターの機能と発現解析2015
- Author(s)
  上村立記、伊藤慎悟、落合祐介、立川正憲、平山未央、和田敬仁、大槻純男
- Organizer
  第31回日本薬学会九州支部大会
- Place of Presentation
  神戸
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-26461544
[Presentation] Tatsuki Uemura, Shingo Ito, Yusuke Ota, Masanori Tachikawa, Takahito Wada, Mio Hirayama, Tetsuya Terasaki, Sumio Ohtsuki: Changes in transport activity and cellular localization by a novel missense mutation in human creatine transporter found in Japanese cerebral creatine deficiency syndromes patients2015
- Author(s)
  Tatsuki Uemura, Shingo Ito, Yusuke Ota, Masanori Tachikawa, Takahito Wada, Mio Hirayama, Tetsuya Terasaki, Sumio Ohtsuki
- Organizer
  Barcelona BioMed Conference Blood Braine Barrier
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2015-10-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461544
[Presentation] 質量分析でタンパク質を測ると何が見えるか2015
- Author(s)
  大槻純男
- Organizer
  第40回西日本薬剤学研究会
- Place of Presentation
  九重
- Year and Date
  2015-08-21
- Invited
- Data Source
  KAKENHI-PROJECT-26293035
[Presentation] 質量分析を利用したタンパク質定量による定量的生命科学への展開2014
- Author(s)
  大槻純男
- Organizer
  第24回WSフォーラム
- Place of Presentation
  福岡
- Year and Date
  2014-11-21
- Invited
- Data Source
  KAKENHI-PROJECT-26293035
[Presentation] Ion library accumulation by RT calibration2014
- Author(s)
  Sumio Ohtsuki
- Organizer
  ABSCIEX users meeting
- Place of Presentation
  Baltimore, USA
- Year and Date
  2014-06-15
- Invited
- Data Source
  KAKENHI-PROJECT-26640092
[Presentation] "多"がつくと大変な標的定量プロテオミクス：一緒に楽をしましょう！2014
- Author(s)
  大槻純男
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-16
- Invited
- Data Source
  KAKENHI-PROJECT-26640092
[Presentation] MS/MS ALL (SWATH) によって進化する定量プロテオミクス2014
- Author(s)
  大槻純男
- Organizer
  日本プロテオーム学会2014年会
- Place of Presentation
  筑波
- Year and Date
  2014-07-17
- Invited
- Data Source
  KAKENHI-PROJECT-26640092
[Presentation] 定量的標的プロテオミクスによるファーマコプロテオミクスアプローチ2011
- Author(s)
  大槻純男
- Organizer
  日本薬学会第131年会
- Place of Presentation
  ツインメッセ静岡、静岡(招待講演)
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-ORGANIZER-22136001
[Presentation] 定量的標的プロテオミクスによって拓かれる新しい創薬研究への展開2010
- Author(s)
  大槻純男
- Organizer
  創剤フォーラム第16回シンポジウム
- Place of Presentation
  東京
- Year and Date
  2010-10-22
- Data Source
  KAKENHI-PLANNED-22136014
[Presentation] Quantification of Transporter/Enzyme Protein in Human Tissue by Mass Spectrometry : A New Path to Pharmacoproteomics (PPx)2010
- Author(s)
  T. Terasaki, S. Ohtsuki
- Organizer
  9th International ISSX meeting, Symposium 3 : Clinical Pharmacology of Drug Transport : From Bench to Bedside
- Place of Presentation
  Istanbul, Turkey
- Year and Date
  2010-09-05
- Data Source
  KAKENHI-PROJECT-18109002
[Presentation] 定量的標的プロテオミクスによって拓かれる新しい創薬研究への展開2010
- Author(s)
  大槻純男
- Organizer
  創剤フォーラム第16回シンポジウム
- Place of Presentation
  アルカディア市ヶ谷、東京(招待講演)
- Year and Date
  2010-10-22
- Data Source
  KAKENHI-ORGANIZER-22136001
[Presentation] Development of highly sensitive simultaneous protein quantification by LC-MS/MS and its application for the research of human disease2010
- Author(s)
  T.Terasaki, S.Ohtsuki
- Organizer
  28th The Japan Endocrine Society (JES) Summer Seminar on Endocrinology & Metabolism (Toward the Progress and Development of Endocrinology
- Place of Presentation
  Nagasaki
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-18109002
[Presentation] Multiplexed-MRM法による膜タンパク質群の一斉定量とファーマコプロテオミクスへの応用2010
- Author(s)
  大槻純男
- Organizer
  日本分析化学会第59年会
- Place of Presentation
  仙台
- Year and Date
  2010-09-16
- Data Source
  KAKENHI-PLANNED-22136014
[Presentation] Multiplexed-MRM法による膜タンパク質群の一斉定量とファーマコプロテオミクスへの応用2010
- Author(s)
  大槻純男
- Organizer
  日本分析化学会第59年会
- Place of Presentation
  東北大学川内キャンパス、仙台(招待講演)
- Year and Date
  2010-09-16
- Data Source
  KAKENHI-ORGANIZER-22136001
[Presentation] Quantitative protein analysis of human glioblastoma2010
- Author(s)
  T.Terasaki, M.Nakada, C.Ikeda, Y.Hayashi, J.Hamada, Y.Sonoda, T.Kumabe, T.Tominaga, S.Ohtsuki
- Organizer
  Neoangiogenesis in Brain Tumours, International meeting of Signal Transduction of the Blood-Brain Barrier, Zurich 2010
- Place of Presentation
  Zurich, Switzerland
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-18109002
[Presentation] Quantitative protein analysis of human glioblastoma, Neoangiogenesis in Brain Tumours2010
- Author(s)
  T. Terasaki, M. Nakada, C. Ikeda, Y. Hayashi, J. Hamada, Y. Sonoda, T. Kumabe, T. Tominaga, S. Ohtsuki
- Organizer
  International meeting of Signal Transduction of the Blood-Brain Barrier, Zurich 2010, Symposium 9
- Place of Presentation
  Zurich, Switzerland
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-18109002
[Presentation] 次世代のファーマコプロテオミクスと中枢神経作用薬の開発2010
- Author(s)
  大槻純男
- Organizer
  第20回日本臨床精神神経薬理学会・第40回日本神経精神薬理学会年会合同年会
- Place of Presentation
  仙台国際センター、仙台(招待講演)
- Year and Date
  2010-09-17
- Data Source
  KAKENHI-ORGANIZER-22136001
[Presentation] Quantification of Transporter/Enzyme Protein in Human Tissue by Mass Spectrometry : A New Path to Pharmacoproteomics (PPx)2010
- Author(s)
  T.Terasaki, S.Ohtsuki
- Organizer
  9th International ISSX meeting
- Place of Presentation
  Istanbul, Turkey
- Year and Date
  2010-09-05
- Data Source
  KAKENHI-PROJECT-18109002
[Presentation] 次世代のファーマコプロテオミクスと中枢神経作用薬の開発2010
- Author(s)
  大槻純男
- Organizer
  第20回日本臨床精神神経薬理学会・第40回日本神経精神薬理学会年会合同年会
- Place of Presentation
  仙台
- Year and Date
  2010-09-17
- Data Source
  KAKENHI-PROJECT-22390026
[Presentation] タンパク質の定量によって拓かれる新しい創薬研究2010
- Author(s)
  大槻純男
- Organizer
  第23回バイオメディカル分析科学シンポジウム
- Place of Presentation
  ホテル大観荘、松島(招待講演)
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-ORGANIZER-22136001
[Presentation] Development of highly sensitive simultaneous protein quantification by LC-MS/MS and its application for the research of human disease2010
- Author(s)
  T. Terasaki, S. Ohtsuki
- Organizer
  28th The Japan Endocrine Society (JES)Summer Seminar on Endocrinology & Metabolism (Toward the Progress and Development of Endocrinology, Session 1 : Advancement of Research Technologies)
- Place of Presentation
  Huis Ten Bosch, Nagasaki
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-18109002
[Presentation] タンパク質の定量によって拓かれる新しい創薬研究2010
- Author(s)
  大槻純男
- Organizer
  第23回,バイオメディカル,分析科学,シンポジウム
- Place of Presentation
  松島
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-PLANNED-22136014
[Presentation] New approach to drug design by quantitative membrane proteomics2009
- Author(s)
  大槻純男, 寺崎哲也
- Organizer
  Special lecture in Seoul Netional University
- Place of Presentation
  Seoul
- Year and Date
  2009-05-20
- Data Source
  KAKENHI-PROJECT-17081002
[Presentation] In vitro-to-in vivo re-construction of blood-brain barrier penetration integrating P-glycoprotein absolute expression, its in vitro activity, and free fractions in plasma and brain.2009
- Author(s)
  内田康雄、大槻純男
- Organizer
  8th Cerebral Vascular International Conference
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19390038
[Presentation] ファーマコプロテオミクスを基盤とする新しい薬物動態研究2009
- Author(s)
  大槻純男, 寺崎哲也
- Organizer
  第13回薬物動態談話会セミナー
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-18109002
[Presentation] プロテオミクス技術に基づくtailormade chemotherapyの展望2009
- Author(s)
  川口桂、元井冬彦、藤川奈々子、有明恭平、横山智、大塚英郎、力山敏樹、片寄友、大峰健、大槻純男、寺崎哲也、江川新一、海野倫明
- Organizer
  第47回日本癌治療学会学術会
- Place of Presentation
  横浜
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21591766
[Presentation] プロテオミクス技術に基づくtailormade chemotherapy の展望2009
- Author(s)
  川口桂、元井冬彦、藤川奈々子、有明恭平、横山智、大塚英郎、力山敏樹、片寄友、大峰健、大槻純男, ほか
- Organizer
  第47回日本癌治療学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21591766
[Presentation] ファーマコプロテオミクス解析によるガン薬剤耐性機構の解明2009
- Author(s)
  大槻純男, 寺崎哲也
- Organizer
  日本医療薬学会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-18109002
[Presentation] 膜タンパク質絶対発現量解析法を応用した薬物脳移行性予測への挑戦2009
- Author(s)
  内田康雄、大槻純男
- Organizer
  日本薬剤学会第24年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-19390038
[Presentation] ファーマコプロテオミクス解析によるガン薬剤耐性機構の解明2009
- Author(s)
  大槻純男
- Organizer
  日本医療薬学会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-17081002
[Presentation] Pharmacoproteomics as a novel method for the prediction of drug delivery to the brain2009
- Author(s)
  T. Terasaki, Y. Uchida, H. Kawakami, Y. Katsukura, J. Kamiie, S. Ohtsuki
- Organizer
  7th Retrometabolism Based Drug Design and Targeting Conference
- Place of Presentation
  Orlando, Florida, USA
- Year and Date
  2009-05-11
- Data Source
  KAKENHI-PROJECT-17081002
[Presentation] 膵癌細胞における薬物輸送担体タンパク群及び関連代謝酵素の網羅的同時絶対定量解析に基づくGEM感受性・耐性規定因子の同定2009
- Author(s)
  川口桂、元井冬彦、大峰健、大槻純男、大塚英郎, ほか
- Organizer
  第109回日本外科学会定期学術集会
- Place of Presentation
  福岡
- Year and Date
  2009-04-02
- Data Source
  KAKENHI-PROJECT-21591766
[Presentation] New approach to drug design by quantitative membrane proteomics2009
- Author(s)
  大槻純男
- Organizer
  Special lecture in Seoul Netional University
- Place of Presentation
  ソウル、韓国
- Year and Date
  2009-05-20
- Data Source
  KAKENHI-PROJECT-20659021
[Presentation] In vitro-to-in vivo re-construction of blood-brain barrier penetration integrating P-glycoprotein absolute expression, its in vitro activity, and free fractions in plasma and brain2009
- Author(s)
  Y. Uchida, S. Ohtsuki, J. Kamiie, T. Terasaki
- Organizer
  8th Cerebral Vascular International Conference (CVB2009)
- Place of Presentation
  Sendai, Japan
- Data Source
  KAKENHI-PROJECT-19390038
[Presentation] 膜タンパク質絶対発現量解析法を応用した薬物脳移行性予測への挑戦 : P-glycoprotein 基質に焦点を当てて2009
- Author(s)
  内田康雄, 大槻純男, 上家潤一, 寺崎哲也
- Organizer
  日本薬剤学会第24年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-19390038
[Presentation] ファーマコプロテオミクスを基盤とする新しい薬物動態研究2009
- Author(s)
  大槻純男
- Organizer
  第13回薬物動態談話会セミナー
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-19390038
[Presentation] Pharmacoproteomics in Cancer Research2009
- Author(s)
  大槻純男, 寺崎哲也
- Organizer
  2009 AAPS Annual Meeting and Exposition
- Place of Presentation
  Los Angels, USA
- Data Source
  KAKENHI-PROJECT-18109002
[Presentation] Transporter protein qunatification for the future of thransporter science. Advanced Technologies for the Future of Transporter Sciences2009
- Author(s)
  T. Terasaki, J. Kamiie, S. Ohtsuki
- Organizer
  The 36th Congress of the International Union of Physiological Sciences (IUPS2009)
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-18109002
[Presentation] ファーマコプロテオミクスを基盤とする新しい薬物動態研究2009
- Author(s)
  大槻純男
- Organizer
  第13回薬物動態談話会セミナー
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-17081002
[Presentation] New approach to drug design by quantitative membrane proteomics2009
- Author(s)
  S. Ohtsuki
- Organizer
  Special lecture in Seoul National University
- Place of Presentation
  Seoul, Korea
- Year and Date
  2009-05-20
- Data Source
  KAKENHI-PROJECT-17081002
[Presentation] ファーマコプロテオミクス解析によるガン薬剤耐性機構の解明2009
- Author(s)
  大槻純男, 寺崎哲也
- Organizer
  日本薬剤学会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-18109002
[Presentation] Multiplexed-MRMによるヒトメンブレンプロテオミクス解析-トリプル四重極質量分析計を用いた新しいアプローチによる膜タンパク質群の高感度同時定量-2009
- Author(s)
  大槻純男
- Organizer
  日本ヒトプロテオーム機構第7回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20659021
[Presentation] New approach to drug design by quantitative membrane proteomics2009
- Author(s)
  S. Ohtsuki
- Organizer
  Special lecture in Seoul Netional University
- Place of Presentation
  Seoul, Korea
- Year and Date
  2009-05-20
- Data Source
  KAKENHI-PROJECT-18109002
[Presentation] Transporter protein quantification for the future of transporter science. Advanced Technologies for the Future of Transporter Sciences2009
- Author(s)
  T. Terasaki, J. Kamiie, S. Ohtsuki
- Organizer
  36th Congress of the International Union of Physiological Sciences
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-17081002
[Presentation] 標的プロテオミクスによる膜タンパク質研究の新たな展開2008
- Author(s)
  大槻純男
- Organizer
  BMA2008、若手シンポジウム
- Place of Presentation
  札幌
- Year and Date
  2008-08-06
- Data Source
  KAKENHI-PROJECT-18109002
[Presentation] Award Lecture for New Investigator Award.2008
- Author(s)
  Sumio Ohtsuki
- Organizer
  2nd ISSX Asian Pacific Regional Meeting
- Place of Presentation
  上海,中国
- Year and Date
  2008-05-12
- Data Source
  KAKENHI-PROJECT-19390038
[Presentation] 標的プロテオミクスによる膜タンパク質研究の新たな展開2008
- Author(s)
  大槻純男
- Organizer
  BMA2008、若手シンポジウム
- Place of Presentation
  札幌
- Year and Date
  2008-08-06
- Data Source
  KAKENHI-PROJECT-17081002
[Presentation] Multiplexed-MRM法による遺伝子情報からの膜タンパク質群の絶対発現量プロフアイル解析2008
- Author(s)
  大槻純男
- Organizer
  アプライドバイオシステムズ・タンパク質研究・プロテオミクス研究セミナー
- Place of Presentation
  東京
- Year and Date
  2008-11-14
- Data Source
  KAKENHI-PROJECT-18109002
[Presentation] Quantitative targeted proteomics as a new strategy for the blood-brain barrier research2008
- Author(s)
  S. Ohtsuki
- Organizer
  2008 the Pharmaceutical Society of Korea Metting
- Place of Presentation
  Jeju, Korea
- Data Source
  KAKENHI-PROJECT-17081002
[Presentation] Multiplexed-MRM法による遺伝子情報からの膜タンパク質群の絶対発現量プロフアイル解析2008
- Author(s)
  大槻純男
- Organizer
  アプライドバイオシステムズ・タンパク質研究・プロテオミクス研究セミナー
- Place of Presentation
  大阪
- Year and Date
  2008-11-12
- Data Source
  KAKENHI-PROJECT-18109002
[Presentation] ABCA1 deficiency does not affect the amyloid-beta elimination across the blood-brain barrier2008
- Author(s)
  S. Ohtsuki
- Organizer
  Gordon Research conference "Barriers of the CNS"
- Place of Presentation
  Tilton, NH. USA
- Data Source
  KAKENHI-PROJECT-17081002
[Presentation] Pharmacoproteomics in Cancer Research2008
- Author(s)
  S. Ohtsuki, R. Iwase, J. Kamiie, K. Ohmine, H. Harigae, T. Terasaki
- Organizer
  2009 AAPS Annual Meeting and Exposition
- Place of Presentation
  Los Angels, CA, USA
- Data Source
  KAKENHI-PROJECT-18109002
[Presentation] Reconstruction of in vivo BBB P-glycoprotein function based on its absolute expression amount and in vitro transport activity2008
- Author(s)
  Y. Uchida, J. Kamiie, S. Ohtsuki, T. Terasaki
- Organizer
  Gordon Research conference "Barriers of the CNS"
- Place of Presentation
  Tilton, NH. USA
- Data Source
  KAKENHI-PROJECT-19390038
[Presentation] 標的プロテオミクスによる膜タシパク質研究の新たな展開2008
- Author(s)
  大槻純男
- Organizer
  BMA2008、若手シンポジウム
- Place of Presentation
  札幌
- Year and Date
  2008-08-06
- Data Source
  KAKENHI-PROJECT-20659021
[Presentation] Award Lecture for New Investigator Award2008
- Author(s)
  S. Ohtsuki
- Organizer
  2nd ISSX Asian Pacific Regional Meeting
- Place of Presentation
  Shanghai, China
- Data Source
  KAKENHI-PROJECT-17081002
[Presentation] Blood-Brain Barrier Pharmacoproteomics (PPx): Targeted absolute proteomics-based pharmacokinetics as a new path for the blood-brain barrier research2008
- Author(s)
  T. Terasaki, Y. Uchida, J. Kamiie, S. Ohtsuki
- Organizer
  BLOOD-BRAIN BARRIER CONSORTIUM CLUB Symposium: 'The impact of efflux transports on CNS drug distribution'
- Place of Presentation
  Gordon Museum, Hodgkin Building, King's College Guy's Campus, London, United Kingdom
- Year and Date
  2008-11-14
- Data Source
  KAKENHI-PROJECT-17081002
[Presentation] Targeted proteomics of the BBB tight junction2008
- Author(s)
  S. Ohtsuki
- Organizer
  Gordon Research conference "Barriers of the CNS"
- Place of Presentation
  Tilton, NH. USA
- Data Source
  KAKENHI-PROJECT-17081002
[Presentation] Quantitative Targeted Proteomicsによる膜タンパク質の網羅的定量技術の開発と応用2008
- Author(s)
  大槻純男
- Organizer
  第5回東北大学バイオサイエンスシンポジウム
- Place of Presentation
  仙台
- Year and Date
  2008-05-19
- Data Source
  KAKENHI-PROJECT-17081002
[Presentation] Reconstruction of in vivo P-glycoprotein activity from in vitro information by targeted absolute proteomics2008
- Author(s)
  S. Ohtsuki, Y. Uchida, T. Terasaki
- Organizer
  2nd World Conference on Magic Bullets (Ehrlich II)
- Place of Presentation
  Nurnberg, Germany
- Data Source
  KAKENHI-PROJECT-19390038
[Presentation] Reconstruction of in vivo P-glycoprotein activity from in vitro infnrmatinn by tarcreted absolute nroteomics2008
- Author(s)
  S. Ohtsuki
- Organizer
  2nd World Conference on Magic Bullets (Ehrlich II)
- Place of Presentation
  Nurnberg, Germany
- Data Source
  KAKENHI-PROJECT-18109002
[Presentation] Targeted proteomics analysis of tight junction proteins expressed at the blood-brain barrier2008
- Author(s)
  S. Ohtsuki, S. Murata, Y. Katsukura, J. Kamiie, P.O. Couraud, T. Terasaki
- Organizer
  The 11th international symposium on "Signal transduction in the Blood-Brain Barriers"
- Place of Presentation
  Amsterdam, Netherlands
- Data Source
  KAKENHI-PROJECT-17081002
[Presentation] Award Lecture for New Investigator Award2008
- Author(s)
  S. Ohtsuki
- Organizer
  2nd ISSX Asian Pacific Regional Meeting
- Place of Presentation
  Shanghai, Chaina
- Data Source
  KAKENHI-PROJECT-19390038
[Presentation] Award Lecture for New Investigator Award2008
- Author(s)
  S. Ohtsuki
- Organizer
  2nd ISSX Asian Pacific Regional Meeting
- Place of Presentation
  Shanghai, Chaina
- Data Source
  KAKENHI-PROJECT-17081002
[Presentation] Reconstruction of P-glycoprotein function at blood-brain barrier based on its absolute expression amount and in vitro transport activity2008
- Author(s)
  Y. Uchida, S. Ohtsuki, J. Kamiie, T. Terasaki
- Organizer
  2008 AAPS Annual Meeting and Exposition
- Place of Presentation
  Atlanta, GA, USA
- Data Source
  KAKENHI-PROJECT-19390038
[Presentation] ain barrier transport protein for the brain drug delivery2007
- Author(s)
  T. Terasaki, J. Kamiie, S. Ohtsuki
- Organizer
  6th Retrometabolism Based Drug Design and Targeting Conference
- Place of Presentation
  Budapest, Hungary
- Data Source
  KAKENHI-PROJECT-17081002
[Presentation] 有機アニオントランスポーターoatp2を介した24(S)hydroxycholesterolの生体膜輸送2007
- Author(s)
  大槻純男
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19390038
[Presentation] Special Lecture: Quantitative proteomics in transporter biology as a new strategy of the drug delivery research2007
- Author(s)
  T. Terasaki, J. Kamiie, S. Ohtsuki
- Organizer
  International Workshop and Symposium on Transport, Metabolism and Disposition
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-17081002
[Presentation] 有機アニオントランスポーター oatp2を介した24(S)hydroxycholesterol の生体膜輸送2007
- Author(s)
  大槻純男, 伊藤慎悟, 松田明大, 堀里子, 阿部高明, 寺崎哲也
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390038
[Presentation] Functional expression of transporters for organic anion at the blood-brain barrier2007
- Author(s)
  T. Terasaki, J. Kamiie, S. Ohtsuki
- Organizer
  7th Cerebral Vascular Biology International Conference
- Place of Presentation
  Ottawa, Canada
- Data Source
  KAKENHI-PROJECT-17081002
[Presentation] Quantitative proteomics as a path to new blood-brain barrier research2007
- Author(s)
  T. Terasaki, J. Kamiie, S. Ohtsuki
- Organizer
  Tenth Symposium Signal Transduction in the Blood-Brain Barriers
- Place of Presentation
  Potsdam, Germany
- Data Source
  KAKENHI-PROJECT-17081002
[Presentation] Quantitative and Simultaneous LC-MS/MS Analysis for Membrane Proteins: Its Application for the Blood-Brain Barrier Biology2006
- Author(s)
  T. Terasaki, J. Kamiie, S. Ohtsuki
- Organizer
  Invited lecture at Seminar of Institut Cochin
- Place of Presentation
  Paris, France
- Year and Date
  2006-12-22
- Data Source
  KAKENHI-PROJECT-17081002
[Presentation] Quantitative proteomics for membrane proteins as a new strategy for the blood-brain barrier biology2006
- Author(s)
  T. Terasaki, J. Kamiie, S. Ohtsuki
- Organizer
  Invited lecture at Seminar of Universite d'Atrois
- Place of Presentation
  Lens, France
- Year and Date
  2006-12-20
- Data Source
  KAKENHI-PROJECT-17081002
[Presentation] Brain-to-blood efflux transporters at the blood brain barrier as a CNS detoxifying system2005
- Author(s)
  T. Terasaki, S. Ohtsuki
- Organizer
  1th Indo-Japanese Conference on Advances in Pharmaceutical Research and Technology - with special emphasis on Drug Discovery and Drug Delivery
- Place of Presentation
  Mumbai, India
- Data Source
  KAKENHI-PROJECT-17081002
[Presentation] ヒトクレアチントランスポーター変異症例におけるクレアチン輸送機能の解明
- Author(s)
  上村立記、伊藤慎悟、落合祐介、立川正憲、平山未央、和田敬仁、大槻純男
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26293035
[Presentation] 新規変異クレアチントランスポーターの機能と発現解析
- Author(s)
  上村立記、伊藤慎悟、落合祐介、立川正憲、平山未央、和田敬仁、大槻純男
- Organizer
  第31回日本薬学会九州支部大会
- Place of Presentation
  福岡
- Year and Date
  2014-12-05 – 2014-12-06
- Data Source
  KAKENHI-PROJECT-26293035

1. TERASAKI Tetsuya (60155463)

# of Collaborated Projects: 9 results

# of Collaborated Products: 58 results
2. ITO Shingo (20466535)

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46. 松井啓隆 (60379849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. 林光博 (50735628)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. 古川龍彦 (40219100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. 南謙太朗 (20735956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. 落合博 (60640753)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
51. 中岡博史 (70611193)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
52. DONG Yu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
53. KITABAYASHI Tomohiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ohtsuki Sumio 大槻 純男

OHTSUKI Sumio 大槻 純男

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New molecular mechanisms for membrane-mediated transcellular transport across the blood brain barrierPrincipal Investigator

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Mcrotransport of the blood-brain barrier and its application to the permeable carrier.Principal Investigator

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Elucidation of pemeable mechanism of new intestinal permeable peptidePrincipal Investigator

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Mechanism of cellular localization of mutated creatine transporter toward therapy for creatine deficiency syndromesPrincipal Investigator

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Ultra-deep quantitative proteomics with RT-normalized peptide databasePrincipal Investigator

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Ohtsuki Sumio 大槻純男

OHTSUKI Sumio 大槻純男