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KASAHARA Toshlko  笠原 敏子

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笠原 敏子  カサハラ トシコ

KASAHARA Toshiko  笠原 敏子

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Researcher Number 60328086
Other IDs
Affiliation (Current) 2025: 帝京大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2007 – 2008: Teikyo University, 医学部, 講師
2002 – 2005: 帝京大学, 医学部, 講師
Review Section/Research Field
Principal Investigator
Functional biochemistry / General medical chemistry / General medical chemistry
Except Principal Investigator
Biological Sciences / Functional biochemistry
Keywords
Principal Investigator
酵母 / 基質認識 / 糖輸送体 / Yeast / Substrate recognition / Chimera / Glucose transporter / GLUT / キメラ / Glut … More
Except Principal Investigator
… More Substrate recognition / Chimera / GLUT / 酵母 / 基質認識 / キメラ / 糖輸送体 / Sorbitol transport / galactose malabsorption / glucose / Sugar transport / Transporter / Membrane transport / MFS / glucose transporter / ソルビトール / グルコース・ガラクトース吸収不全症 / 糖輸送 / 輸送体 / 膜輸送 / Yeast / Glucose transporter / Hxt2 Less
  • Research Projects

    (5 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (2 People)
  •  Structure and function of human glucose transporter GLUT1Principal Investigator

    • Principal Investigator
      KASAHARA Toshlko
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Teikyo University
  •  MFS transporter : Analysis of transport mechanism by correlation of gene and structure

    • Principal Investigator
      KASAHARA Michihiro
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Teikyo University
  •  Molecular mechanism of yeast glucose transporterPrincipal Investigator

    • Principal Investigator
      KASAHARA Toshiko
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Teikyo University
  •  Substrate recognition site o f human glucose transporterPrincipal Investigator

    • Principal Investigator
      KASAHARA Toshiko
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Teikyo University
  •  Functional analysis of sugar transporter

    • Principal Investigator
      KASAHARA Michihiro
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Teikyo University

All 2009 2008 2007 2006 2004

All Journal Article Presentation

  • [Journal Article] Identification of a key residue determining substrate affinity in the human glucose transporter GLUT12009

    • Author(s)
      Toshiko Kasahara, et al.
    • Journal Title

      Biochimica et Biophysica Acta Biomembranes (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590288
  • [Journal Article] Identification of a key residue determining substrate affinity in the human glucose transporter GLUT12009

    • Author(s)
      Kasahara, T., Maeda, M., Boles, E. and Kasahara, M.
    • Journal Title

      Biochim. Biophys. Acta 1788

      Pages: 1051-1055

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590288
  • [Journal Article] Identification by comprehensive chimeric analysis of a key residue responsible for high affinity glucose transporter by yeast Hxt22007

    • Author(s)
      Kasahara, T., Maeda, M., Ishiguro, M. and Kasahara, M.
    • Journal Title

      J.Biol.Chem. 282

      Pages: 13146-13150

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590288
  • [Journal Article] Identification by comprehensive chimeric analysis of a key residue responsible for high affinity glucose transporter by yeast Hxt22007

    • Author(s)
      Kasahara, T., Maeda, M., Ishiguro, M. and Kasahara, M.
    • Journal Title

      J. Biol. Chem. 282

      Pages: 13146-13150

    • Data Source
      KAKENHI-PROJECT-19590288
  • [Journal Article] Eight amino acid residues in transmembrane segments of yeast glucose transporter Hxt2 are required for high-affinity transport2006

    • Author(s)
      Kasahara, T., Ishiguro, M., Kasahara, M.
    • Journal Title

      J. Biol. Chem. 281(in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16055201
  • [Journal Article] Eight amino acid residues in transmembrane segments of yeast glucose transporter Hxt2 are required for high-affinity transport.2006

    • Author(s)
      Kasahara, T.et al.
    • Journal Title

      J.Biol.Chem. 281(In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16055201
  • [Journal Article] Eight amino acid residues in transmembrane segments of yeast glucose transporter Hxt2 are required for high-affinity transport2006

    • Author(s)
      Kasahara, T., Ishiguro, M., Kasahara, M.
    • Journal Title

      J.Biol.Chem. 281(in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16570123
  • [Journal Article] Eight amino acid residues in transmembrane segments of yeast glucose transporter Hxt2 are required for high-affinity transport2006

    • Author(s)
      Kasahara, T., Ishiguro, M., Kasahara, M.
    • Journal Title

      J. Biol. Chem 281(In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16570123
  • [Journal Article] Comprehensive chimeric analysis of amino acid residues critical for high affinity glucose transport by Hxt2 of Saccharomyces cerevisiae2004

    • Author(s)
      Kasahara, T., Ishiguro, M., Kasahara, M.
    • Journal Title

      J. Biol. Chem. 279

      Pages: 30274-30278

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16055201
  • [Journal Article] Comprehensive chimeric analysis of amino acid residues critical for high affinity glucose transport by Hxt2 of Saccharomyces cerevisiae.2004

    • Author(s)
      Kasahara, T., Ishiguro, M, Kasahara, M
    • Journal Title

      J.Biol.Chem. 279

      Pages: 30274-30278

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16055201
  • [Journal Article] Comprehensive chimeric analysis of amino acid residues critical for high affinity glucose transport by Hxt2 of Saccharomyces cerevisiae.2004

    • Author(s)
      Kasahara, T., Ishiguro, M., Kasahara, M.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 30274-30278

    • Data Source
      KAKENHI-PROJECT-16055201
  • [Journal Article] Comprehensive chimeric analysis of amino acid residues critical for high-affinity glucose transport by Saccharomyces cerevisiae2004

    • Author(s)
      Kasahara, T., Ishiguro, M., Kasahara, M.
    • Journal Title

      J. Biol. Chem. 279

      Pages: 30274-30278

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16570123
  • [Journal Article] Comprehensive chimeric analysis of amino acid residues critical for high-affinity glucose transport by Saccharomyces cerevisiae2004

    • Author(s)
      Kasahara, T., Ishiguro, M., Kasahara, M.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 30274-30278

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16570123
  • [Presentation] 酵母Hxt familyに属するグルコース輸送体のそれぞれの基質親和性を規定する膜貫通領域7にある部位2008

    • Author(s)
      笠原敏子、笠原道弘
    • Organizer
      酵母遺伝学フォーラム第41回研究報告会
    • Place of Presentation
      北海道大学学術交流会館
    • Data Source
      KAKENHI-PROJECT-19590288
  • [Presentation] ヒト糖輸送体GLUT1の基質親和性を規定するアミノ酸残基2008

    • Author(s)
      笠原道弘, 他
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会 合同大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19590288
  • [Presentation] 酵母の親和性の異なる糖輸送体に共通する親和性決定の鍵となるアミノ酸残基2008

    • Author(s)
      笠原敏子、笠原道弘
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19590288
  • [Presentation] ヒト糖輸送体GLUT1の基質親和性を規定するアミノ酸残基2008

    • Author(s)
      笠原道弘、笠原敏子
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19590288
  • [Presentation] 酵母の親和性の異なる糖輸送体に共通する親和性決定の鍵となるアミノ酸残基2008

    • Author(s)
      笠原敏子, 他
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会 合同大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19590288
  • [Presentation] 酵母糖輸送体Hxt7の膜貫通部位5,7,8のCysteine-scanning mutagenesisによる糖輸送に関与するアミノ酸残基の同定2007

    • Author(s)
      笠原 道弘、前田 眞理、笠原 敏子
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会 合同大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-11
    • Data Source
      KAKENHI-PROJECT-19590288
  • [Presentation] A key residue responsible for determining affinity for glucose in human glucose transporter GLUT1 expressed in a heterologous yeast system2007

    • Author(s)
      笠原敏子、前田眞理、E, Boles、笠原道弘
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-11
    • Data Source
      KAKENHI-PROJECT-19590288
  • [Presentation] 酵母の糖輸送体Hxt2の高親和性基質認識に関与するアミノ酸残基間の相互作用2007

    • Author(s)
      前田 眞理、笠原 敏子、石黒 正路、笠原 道弘
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会 合同大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-11
    • Data Source
      KAKENHI-PROJECT-19590288
  • [Presentation] 酵母の糖輸送体Hxt2の高親和性基質認識に関与するアミノ酸残基間の相互作用2007

    • Author(s)
      前田眞理、笠原敏子、石黒正路、笠原道弘
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-11
    • Data Source
      KAKENHI-PROJECT-19590288
  • [Presentation] 酵母糖輸送体Hxt7の膜貫通部位5, 7, 8のCysteine-scanning mutagenesisによる糖輸送に関与するアミノ酸残基の同定2007

    • Author(s)
      笠原道弘、前田眞理、笠原敏子
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Place of Presentation
      パシフイコ横浜
    • Year and Date
      2007-12-11
    • Data Source
      KAKENHI-PROJECT-19590288
  • [Presentation] A key residue responsible for determining affinity for glucose in human glucose transporter GLUT1 expressed in a heterologous yeast system2007

    • Author(s)
      笠原 敏子、前田 眞理、E.Boles、笠原 道弘
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会 合同大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-11
    • Data Source
      KAKENHI-PROJECT-19590288
  • 1.  KASAHARA Michihiro (40010102)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 2.  豊福 恭子
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results

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