AMANO Kenji 天野賢治

Researcher Number	60333340
Other IDs
Affiliation (based on the past Project Information) *help	2017: 国立研究開発法人理化学研究所, その他, 研究員 2015 – 2016: 国立研究開発法人理化学研究所, 脳科学総合研究センター, 研究員 2008 – 2009: The Institute of Physical and Chemical Research, 神経遺伝研究チーム, リサーチアソシエイト 2007: The Institute of Physical and Chemical Research, 神経遺伝研究チーム, リサーチアソシエイト 2004 – 2006: 独立行政法人理化学研究所, 神経遺伝研究チーム, リサーチアソシエイト
Review Section/Research Field	Principal Investigator Pediatrics Except Principal Investigator Psychiatric science
Keywords	Principal Investigator DSCAM / トリソミー / 過剰発現 / Ts1Cje / ダウン症候群 / マウスモデル / 動試験 / Ts1CjeDSCAM / TslCje / 精神遅滞 … More / 摘出脳幹-脊髄標本 / 電気生理学実験 / 神経系免疫グロブリンスーパーファミリー( / 呼吸障害 / ニューロンネットワーク / 致死 / 延髄呼吸中枢 / 吸息先行型ニューロン / 免疫グロブリンスーパーファミリー / 中枢性呼吸障害 / ノックアウトマウス / Affymetrix / 生後0日目 / GeneChip / 遺伝子発現解析 … More Except Principal Investigator 大脳基底核 / Stxbp1 / Ampakine / Munc18-1 / 大田原症候群 / intellectual disability / ampakine / 攻撃性 / てんかん / シナプス伝達 / MUNC18-1 / STXBP1 Less

Circuit mechanisms for intractable epilepsy and intellectual disabilities caused by impairments of synaptic transmission
- Principal Investigator
  
  Miyamoto Hiroyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Institute of Physical and Chemical Research
Investigation of roles of DSCAM in mental retardation of Down syndromePrincipal Investigator
- Principal Investigator
  
  AMANO Kenji
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  The Institute of Physical and Chemical Research
出生後24時間以内に死亡するDscamノックアウトマウスを用いた呼吸障害の解析Principal Investigator
- Principal Investigator
  
  天野賢治
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  The Institute of Physical and Chemical Research
ダウン症マウスモデル(Ts1Cje)を用いた体系的遺伝子発現解析Principal Investigator
- Principal Investigator
  
  天野賢治
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  The Institute of Physical and Chemical Research

All 2018 2017 2007 2004

All Journal Article Presentation

[Journal Article] DYRK1A-haploinsufficiency in mice causes autistic-like features and febrile seizures2018
- Author(s)
  Raveau Matthieu、Shimohata Atsushi、Amano Kenji、Miyamoto Hiroyuki、Yamakawa Kazuhiro
- Journal Title
  
  Neurobiology of Disease
  
  Volume: 110 Pages: 180-191
- DOI
  10.1016/j.nbd.2017.12.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09848, KAKENHI-PROJECT-18K07577
[Journal Article] Potentiation of excitatory synaptic transmission ameliorates aggression in mice with Stxbp1 haploinsufficiency2017
- Author(s)
  Miyamoto Hiroyuki、Shimohata Atsushi、Abe Manabu、Abe Teruo、Mazaki Emi、Amano Kenji、Suzuki Toshimitsu、Tatsukawa Tetsuya、Itohara Shigeyoshi、Sakimura Kenji、Yamakawa Kazuhiro
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 26 Issue: 24 Pages: 4961-4974
- DOI
  10.1093/hmg/ddx379
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01972, KAKENHI-PROJECT-17K19444, KAKENHI-PROJECT-15H04290, KAKENHI-PROJECT-15K09848, KAKENHI-PROJECT-16H06276
[Journal Article] Ts1Cje Down syndrome model mice exhibit environmental stimuli-triggered locomotor hyperactivity and sociability concurrent with increased flux through central dopamine and serotonin metabolism.2017
- Author(s)
  Shimohata A, Ishihara K, Hattori S, Miyamoto H, Morishita H, Ornthanalai G, Raveau M, Ebrahim AS, Amano K, Yamada K, Sago H, Akiba S, Mataga N, Murphy NP, Miyakawa T, Yamakawa K.
- Journal Title
  
  Exp Neurol
  
  Volume: S0014-4886(17) Pages: 30069-9
- DOI
  10.1016/j.expneurol.2017.03.009
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06462, KAKENHI-PROJECT-25242078, KAKENHI-PROJECT-25460077, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-15K09848
[Journal Article] Dosage-dependent over-expression of genes in the trisomic region of Ts1Cje mouse model for Down syndrome2004
- Author(s)
  Amano K. et al.
- Journal Title
  
  Human Molecular Genetics Vol.13, No.13
  
  Pages: 1333-1340
- Data Source
  KAKENHI-PROJECT-16790604
[Journal Article] Dosage-dependent over-expression of genes in the trisomic region of Ts1Cjemouse model for Down syndrome2004
- Author(s)
  Amano K. et al.
- Journal Title
  
  Human Molecular Genetics Vol.13, No.13
  
  Pages: 1333-1340
- Data Source
  KAKENHI-PROJECT-16790604
[Presentation] Dscam deficiency causes congenital central hypoventilation2007
- Author(s)
  天野賢治
- Organizer
  第2回MCCS-Asiaシンポジウム
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-09-08
- Data Source
  KAKENHI-PROJECT-18790744
[Presentation] Loss of pre-inspiratory neuron synchroneity in mice with Dscam1 deficiency2007
- Author(s)
  Kenji Amano
- Organizer
  Society for Neuroscience, 2007
- Place of Presentation
  San Diego Convention Center
- Year and Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-18790744
[Presentation] 乳幼児突然死症候群モデルとしてのDscamノックアウトマウス2007
- Author(s)
  天野賢治
- Organizer
  第49回日本小児神経学会総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2007-07-06
- Data Source
  KAKENHI-PROJECT-18790744

1. Miyamoto Hiroyuki (90312280)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 阿部学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 宮川剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

AMANO Kenji 天野 賢治

Research Projects

Research Products

Co-Researchers

Circuit mechanisms for intractable epilepsy and intellectual disabilities caused by impairments of synaptic transmission

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of roles of DSCAM in mental retardation of Down syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

出生後24時間以内に死亡するDscamノックアウトマウスを用いた呼吸障害の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ダウン症マウスモデル(Ts1Cje)を用いた体系的遺伝子発現解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] DYRK1A-haploinsufficiency in mice causes autistic-like features and febrile seizures2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Potentiation of excitatory synaptic transmission ameliorates aggression in mice with Stxbp1 haploinsufficiency2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ts1Cje Down syndrome model mice exhibit environmental stimuli-triggered locomotor hyperactivity and sociability concurrent with increased flux through central dopamine and serotonin metabolism.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dosage-dependent over-expression of genes in the trisomic region of Ts1Cje mouse model for Down syndrome2004

Author(s)

Journal Title

Data Source

[Journal Article] Dosage-dependent over-expression of genes in the trisomic region of Ts1Cjemouse model for Down syndrome2004

Author(s)

Journal Title

Data Source

[Presentation] Dscam deficiency causes congenital central hypoventilation2007

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Loss of pre-inspiratory neuron synchroneity in mice with Dscam1 deficiency2007

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 乳幼児突然死症候群モデルとしてのDscamノックアウトマウス2007

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

AMANO Kenji 天野賢治