IKEMIZU SHINJI 池水信二

… Alternative Names

IKEMIZU Shinji 池水信二

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Researcher Number	60333522
Other IDs
External Links
Affiliation (Current)	2025: 熊本大学, 大学院生命科学研究部(薬), 准教授
Affiliation (based on the past Project Information) *help	2013 – 2018: 熊本大学, 大学院生命科学研究部(薬), 准教授 2015: 熊本大学, 生命科学研究部, 准教授 2012 – 2013: 熊本大学, 大学院生命科学研究部, 准教授 2009 – 2011: Kumamoto University, 大学院・生命科学研究部, 准教授 2007 – 2008: Kumamoto University, 大学院・医学薬学研究部, 准教授 … More 2005 – 2006: 熊本大学, 大学院医学薬学研究部, 助教授 2003 – 2004: 熊本大学, 大学院・医学薬学研究部, 助教授 2001 – 2002: 熊本大学, 大学院・薬学研究科, 助教授 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Structural biochemistry / Biological Sciences / Structural biochemistry Except Principal Investigator Biological pharmacy / Biological Sciences
Keywords	Principal Investigator 構造生物学 / シグナル伝達 / サイトカイン / 分子認識 / 免疫学 / 免疫 / 分子認識機構 / 生体分子 / 蛋白質 / 補助刺激分子 … More / 受容体 / 分化 / 複合体 / 生物物理 / 免疫応答 / T細胞活性化 / タンパク質 / サイトカイン受容体複合体 / X線結晶解析 / 結晶構造 / サイトカイン受容体 / 構造解析 / 結晶学 / T細胞 … More Except Principal Investigator MEF / CFTR / ETS transcription factor / PML nuclear body / lysozyme / calreticulin / calnexin / molecular chaperone / heat shock protein / vitamin K / 分子シャペロン / Heat Shock Protein / ガン / ガン抑制遺伝子 / 温熱療法 / クルクミン / カルレティキュリン / カルネキシン / 遺伝病 / 蛋白質-蛋白質相互作用 / 染色体凝縮 / 3次元構造 / 蛋白質の結晶化 / 蛋白質の大量調製 / 巨核球分化 Less

Structural basis of the Th1 cell differentiation.Principal Investigator
- Principal Investigator
  
  Ikemizu Shinji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kumamoto University
T細胞制御機構の構造生物学的基盤Principal Investigator
- Principal Investigator
  
  池水信二
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
Structural studies of immune responses.Principal Investigator
- Principal Investigator
  
  Ikemizu Shinji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kumamoto University
炎症性サイトカインと受容体の構造生物学的認識機構の解明Principal Investigator
- Principal Investigator
  
  池水信二
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
IL-27の構造生物学的シグナル伝達機構の解明Principal Investigator
- Principal Investigator
  
  池水信二
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
Structural basis of the molecular recognitions involve T cell differentiation.Principal Investigator
- Principal Investigator
  
  IKEMIZU Shinji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kumamoto University
IL-2/IL-2R複合体形成機構の構造生物学的研究Principal Investigator
- Principal Investigator
  
  池水信二
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
IL-2/Il-2R複合体形成機構の構造生物学的基盤Principal Investigator
- Principal Investigator
  
  池水信二
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
補助刺激分子の構造生物学的研究Principal Investigator
- Principal Investigator
  
  池水信二
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
CD28を介した補助刺激の構造を基にしたシグナル伝達機構の解明Principal Investigator
- Principal Investigator
  
  池水信二
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
補助刺激分子のシグナル伝達機構の構造生物学的研究Principal Investigator
- Principal Investigator
  
  池水信二
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kumamoto University
Development of therapeutic ways targeting molecular chaperones and ets transcription factors
- Principal Investigator
  
  KAI Hirofumi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kumamoto University
造血幹細胞から巨核球への分化に関わる蛋白質群の3次元構造と機能
- Principal Investigator
  
  山縣ゆり子
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University

All 2019 2018 2017 2013 2012 2011 2010 2009 2008 2007 2006 2005

All Journal Article Presentation Book Patent

[Book] Structural Biology in Immunology2018
- Author(s)
  Shinji Ikemizu，Simon J. Davis
- Total Pages
  186
- Publisher
  ELSEVIER
- ISBN
  9780128033708
- Data Source
  KAKENHI-PROJECT-16K07276
[Book] 日本臨牀関節リウマチ(第2版)2010
- Author(s)
  池鯉鮒麻美, 池水信二
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-20370040
[Book] 関節リウマチ(第2版) 寛解を目指す治療の新時代2010
- Author(s)
  池鯉鮒麻美, 池水信二
- Publisher
  日本臨林社
- Data Source
  KAKENHI-PROJECT-20370040
[Book] 臨床薬理の進歩、282008
- Author(s)
  池水信二, 他
- Publisher
  臨床薬理研究振興財団
- Data Source
  KAKENHI-PROJECT-20370040
[Journal Article] X-ray Structure Analysis of Human Oxidized Nucleotide Hydrolase MTH1 using Crystals Obtained under Microgravity2019
- Author(s)
  Nakamura T, Hirata K, Fujimiya K, Chirifu M, Arimori T, Tamada T, Ikemizu S, Yamagata Y
- Journal Title
  
  International journal of microgravity science and application
  
  Volume: 36 Issue: 1 Pages: 360103
- DOI
  10.15011//jasma.36.360103
- NAID
  130007769928
- ISSN
  2188-9783
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06600, KAKENHI-PROJECT-16K07276, KAKENHI-PROJECT-18H02389
[Journal Article] Crystal Structure of the CD200/CD200R Complex2019
- Author(s)
  Takumi Shirouzono, Ryuto Sakiyama, Mami Chirifu, Toshiyuki Kojima, Hajime Karasuyama, Shinji Ikemizu,
- Journal Title
  
  SPring-8/SACLA Research Report
  
  Volume: 7(1) Pages: 1-4
- NAID
  130007969603
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07276
[Journal Article] A molecular and preclinical comparison of the PD-1?targeted T-cell checkpoint inhibitors nivolumab and pembrolizumab2017
- Author(s)
  Fessas Petros、Lee Hassal、Ikemizu Shinji、Janowitz Tobias
- Journal Title
  
  Seminars in Oncology
  
  Volume: 44 Issue: 2 Pages: 136-140
- DOI
  10.1053/j.seminoncol.2017.06.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07276
[Journal Article] Crystallization and preliminary X-ray analysis of human MTH1 with a homogeneous N-terminus.2013
- Author(s)
  Koga Y, Inazato M, Nakamura T, Hashikawa C, Chirifu M, Michi A, Yamashita T, Toma S, Kuniyasu A, Ikemizu S, Nakabeppu Y, Yamagata Y.
- Journal Title
  
  Acta Crystallogr Sect F Struct Biol Cryst Commun
  
  Volume: 69(Pt 1) Issue: 1 Pages: 45-48
- DOI
  10.1107/s1744309112048002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22221004, KAKENHI-PROJECT-23390027, KAKENHI-PROJECT-23659025, KAKENHI-PROJECT-23790052, KAKENHI-PROJECT-25440031, KAKENHI-PLANNED-22131007, KAKENHI-PUBLICLY-23121523, KAKENHI-PUBLICLY-24113719
[Journal Article] Mutants of lymphotoxin-<alpha> with augmented cytotoxic activity via TNFR1 for use in cancer therapy.2013
- Author(s)
  Morishige, T., Narimatsu, S., Ikemizu, S., Tsunooda, S., Tsutsumi Y., Mukai, Y., Okada, N., Nakagawa, S.
- Journal Title
  
  Cytokine
  
  Volume: 61 Pages: 578-584
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25121727
[Journal Article] Structure and interactions of the human programmed cell death 1 receptor.2013
- Author(s)
  Cheng, X., Veverka, V., Radhakrishnan, A., Waters, L.C., Muskett, F.W., Morgan, S., Huo, J., Yu, C., Evans, E.J., Leslie, A.J., Griffiths, M., Stubberfield, C., Griffin, R., Henry, A.J., Jansson, A., Ladbury, J.E., Ikemizu, S., Carr, M.D., Davis, S.J.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Pages: 11771-11785
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25440031
[Journal Article] Crystallization and preliminary X-ray analysis of human MTH1 with a homogeneous N-terminus.2013
- Author(s)
  Koga, Y., Inazato, M., Nakamura, T., Hashikawa, C., Chirifu, M., Michi, A., Yamashita, T., Toma, S., Kuniyasu, A., Ikemizu, S., Nakabeppu, Y., & Yamagata, Y.
- Journal Title
  
  Acta Crysatllogr. F
  
  Volume: 69 Pages: 45-48
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25121727
[Journal Article] Impact of antibodies against amyloidogenic transthyretin (ATTR) on phenotypes of patients with familial amyloidotic polyneuropathy (FAP) ATTR Valine30Methionine.2013
- Author(s)
  Obayashi, K., Tasaki, M., Jono, H., Ueda, M., Shinriki, S., Misumi, Y., Yamashita, T., Oshima, T., Nakamura, T., Ikemizu, S., Anan, I., Suhr, O., & Ando, Y.
- Journal Title
  
  Clin. Chim. Acta
  
  Volume: 419 Pages: 127-131
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25121727
[Journal Article] Structure and interactions of the human programmed cell death 1 receptor.2013
- Author(s)
  Cheng, X., Veverka, V., Radhakrishnan, A., Waters, L.C., Muskett, F.W., Morgan, S., Huo, J., Yu, C., Evans, E.J., Leslie, A.J., Griffiths, M., Stubberfield, C., Griffin, R., Henry, A.J., Jansson, A., Ladbury, J.E., Ikemizu, S., Carr, M.D., Davis, S.J.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Pages: 11771-11785
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25121727
[Journal Article] mpact of antibodies against amyloidogenic transthyretin (ATTR) on phenotypes of patients with familial amyloidotic polyneuropathy (FAP) ATTR Valine30Methionine.2013
- Author(s)
  Obayashi, K., Tasaki, M., Jono, H., Ueda, M., Shinriki, S., Misumi, Y., Yamashita, T., Oshima, T., Nakamura, T., Ikemizu, S., Anan, I., Suhr, O., & Ando, Y.
- Journal Title
  
  Clin. Chim. Acta
  
  Volume: 419 Pages: 127-131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25440031
[Journal Article] Mutants of lymphotoxin-<alpha> with augmented cytotoxic activity via TNFR1 for use in cancer therapy.2013
- Author(s)
  Morishige, T., Narimatsu, S., Ikemizu, S., Tsunooda, S., Tsutsumi Y., Mukai, Y., Okada, N., Nakagawa, S.
- Journal Title
  
  Cytokine
  
  Volume: 61 Pages: 578-584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25440031
[Journal Article] Impact of antibodies against amyloidogenic transthyretin (ATTR) on phenotypes of patients with familial amyloidotic polyneuropathy (FAP) ATTR Valine30Methionine2013
- Author(s)
  Obayashi K, Tasaki M, Jono H, Ueda M, Shinriki S, Misumi Y, Yamashita T, Oshima T, Nakamura T, Ikemizu S, Anan I, Suhr O, Ando Y
- Journal Title
  
  Clin Chim Acta
  
  Volume: 419 Pages: 127-31
- DOI
  10.1016/j.cca.2013.02.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500430, KAKENHI-PROJECT-23659303, KAKENHI-PROJECT-24249036, KAKENHI-PROJECT-24590699, KAKENHI-PROJECT-24790557, KAKENHI-PROJECT-25870541, KAKENHI-PUBLICLY-23121523
[Journal Article] Preparation, Crystallization and Preliminary X-ray Diffraction Studies of the Glycosylated Form of Human Interleukin-232012
- Author(s)
  T.Shirouzono, et al
- Journal Title
  
  Acta Cryst
  
  Volume: F68(in press) Issue: 4 Pages: 432-435
- DOI
  10.1107/s1744309112005295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390008, KAKENHI-PUBLICLY-23121523
[Journal Article] IL-2 and IL-15 signaling complex: different but the same.2012
- Author(s)
  Ikemizu, S., Chirifu, M. Davis, S.
- Journal Title
  
  Nature Immunology
  
  Volume: 13 Issue: 12 Pages: 1141-1142
- DOI
  10.1038/ni.2472
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23121523
[Journal Article] Rigid-body ligand recognition drives cytotoxic T-lymphocyte antigen 4 (CTLA-4) receptor triggering.2011
- Author(s)
  Yu, C., Sonnen, A.F.-P., George, R., Dessailly, B.H., Stagg, L.J., Evans, E.J., Orengo, C.A., Stuart, D.I., Ladbury, J.E., Ikemizu, S., Gilbert, R.J.C., Davis, S.J.
- Journal Title
  
  J.Biol.Chem. 286
  
  Pages: 6685-6696
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370040
[Journal Article] Rigid-body ligand recognition drives cytotoxic T-lymphocyte antigen 4 (CTLA-4) receptor triggering2011
- Author(s)
  Yu, C, Sonnen, A.F-P, George, R, Dessailly, BH, Stagg, L.J., Evans, E.J., Orengo, C.A., Stuart, D.I., Ladbury, J.E., Ikemizu, S., Gilbert, R.J.C., Davis, S.J.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 286 Issue: 8 Pages: 6685-6696
- DOI
  10.1074/jbc.m110.182394
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23121523
[Journal Article] Diverse Substrate Recognition and Hydrolysis Mechanisms of Human NUDT52011
- Author(s)
  Takao Arimori, at al
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 39 Issue: 20 Pages: 8972-8983
- DOI
  10.1093/nar/gkr575
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22131007, KAKENHI-PROJECT-22370003, KAKENHI-PROJECT-22570007, KAKENHI-PUBLICLY-23121523, KAKENHI-PROJECT-23790052
[Journal Article] Rigid-body ligand recognition drives cytotoxic T-lymphocyte antigen 4 (CTLA-4) receptor triggering.2011
- Author(s)
  Yu, C., Sonnen, A.F.-P., George, R., Dessailly, B.H., Stagg, L.J., Evans, E.J., Orengo, C.A., Stuart, D.I., Ladbury, J.E., Ikemizu, S., Gilbert, R.J.C., Davis, S.J.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 286 Pages: 6686-6696
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370040
[Journal Article] Creation of lysine-deficient mutant lymphotoxin-alpha with receptor selectivity by using a phage display system2010
- Author(s)
  Yoshioka, Y., Watanabe, H., Morishige, T., Yao, X., Ikemizu, S., Naga o, C., Ahmad, S., Mizuguchi, K., Tsunoda, S., Tsutsumi, Y., Mukai, Y., Okada, N., Nakagawa, S.
- Journal Title
  
  Biomaterials 31
  
  Pages: 1935-1943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20051019
[Journal Article] The crystal structure of green tea polyphenol(-) -epigallocatechingallate (EGCG)-transthyretin complex reveals novel binding site distinct from thyroxine binding site2010
- Author(s)
  Miyata, M., Sato, T., Kugimiya, M., Sho, M., Nakamura, T., Ikemizu, S., Chirifu, M., Mizuguchi, M., Nabeshima, Y., Suwa, Y., Morioka, H., Arimori, T., Suico, M. A., Shuto, T., Sako, Y., Momohara, M., Koga, T., Morino-Koga, S., Yamagata, Y., Kai, H.
- Journal Title
  
  Biochemistry 49
  
  Pages: 6104-6114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370040
[Journal Article] The crystal structure of green tea polyphenol(-)-epigallocatechingallate (EGCG)-transthyretin complex reveals novel binding site distinct from thyroxine binding site2010
- Author(s)
  Miyata, M., Sato, T., Kugimiya, M., Sho, M., Nakamura, T., Ikemizu, S., Chirifu, M., Mizuguchi, M., Nabeshima, Y., Suwa, Y., Morioka, H., Arimori, T., Suico, M.A., Shuto, T., Sako, Y., Momohara, M., Koga, T., Morino-Koga, S., Yamagata, Y., Kai, H.
- Journal Title
  
  Biochemistry
  
  Volume: 49 Pages: 6014-6114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370040
[Journal Article] Creation of lysine-deficient mutant lymphotoxin-alpha with receptor selectivity by using a phage display system2010
- Author(s)
  Yoshioka, Y., Watanabe, H., Morishige, T., Yao, X., Ikemizu, S., Nagao, C., Ahmad, S., Mizuguchi, K., Tsunoda, S., Tsutsumi, Y., Mukai, Y., Okada, N., Nakagawa, S.
- Journal Title
  
  Biomaterials 31
  
  Pages: 1935-1943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370040
[Journal Article] Role of the Glutamic Acid 54 Residue in Transthyretin Stability and Thyroxine Binding2010
- Author(s)
  Miyata M, Sato T, Mizuguchi M, Nakamura T, Ikemizu S, Nabeshima Y, Susuki S, Suwa Y, Morioka H, Ando Y, Suico MA, Shuto T, Koga T, Yamagata Y, Kai H.
- Journal Title
  
  Biochemistry 49
  
  Pages: 114-123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370040
[Journal Article]2010
- Author(s)
  池鯉鮒麻美, 池水信二
- Journal Title
  
  関節リウマチ(日本臨牀社)
  
  Pages: 145-148
- Data Source
  KAKENHI-PROJECT-20370040
[Journal Article] Role of the Glutamic Acid 54 Residue in Transthyretin Stability and Thyroxine Binding2010
- Author(s)
  Miyata M, Sato T, Mizuguchi M, Nakamura T, Ikemizu S, Nabeshima Y, Susuki S, Suwa Y, Morioka H, Ando Y, Suico MA, Shuto T, Koga T, Yamagata Y, Kai H.
- Journal Title
  
  Biochemistry 49
  
  Pages: 114-123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20051019
[Journal Article] Structure-Function Relationship of Tumor Necrosis Factor (TNF) and Its Receptor Interaction Based on 3D Structural Analysis of a Fully Active TNFR1-Selective TNF Mutant.2009
- Author(s)
  Mukai, Y., Shibata, H., Nakamura, T., Yoshioka, Y., Abe, Y., Nomura, T., Taniai, M., Ohta, T., Ikemizu, S., Nakagawa, S., Tsunoda, S., Kamada, H., Yamagata, Y., Tsutsumi, Y.
- Journal Title
  
  J.Mol.Biol. 285
  
  Pages: 1221-1229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20051019
[Journal Article] Structure-Function Relationship of Tumor Necrosis Factor(TNF)and Its Receptor Interaction Based on 3D Structural Analysis of a Fully Active TNFR1-Selective TNF Mutant2009
- Author(s)
  Mukai, Y., Shibata, H., Nakamura, T., Yoshioka, Y., Abe, Y., Nomura, T., Taniai, M., Ohta, T., Ikemizu, S., Nakagawa, S., Tsunoda, S., Kamada, H., Yamagata, Y., Tsutsumi, Y.
- Journal Title
  
  J.Mol.Biol. 285
  
  Pages: 1221-1229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370040
[Journal Article] Structure-Function Relationship of Tumor Necrosis Factor (TNF) and Its Receptor Interaction Based on 3D Structural Analysis of a Fully Active TNFR1-Selective TNF Mutant.2009
- Author(s)
  Mukai, Y., Shibata, H., Nakamura, T., Yoshioka, Y., Abe, Y., Nomura, T., Taniai, M., Ohta, T., Ikemizu, S., Nakagawa, S., Tsunoda, S., Kamada, H., Yamagata, Y., Tsutsumi, Y.
- Journal Title
  
  J.Mol.Biol. 285
  
  Pages: 1221-1229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370040
[Journal Article] Preparation, crystallization and preliminary X-ray diffraction analysis of the DNA-binding domain of the Ets transcription factor in complex with target DNA2008
- Author(s)
  Suwa, Y., Nakamura, T., Toma, S., Ikemizu, S., Kai, H., Yamagata, Y.
- Journal Title
  
  Acta Crysatllogr. F64
  
  Pages: 171-174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370040
[Journal Article] Role of the conformational change in the C-terminus of b2-microglobulin in dialysis- related amyloidosis2008
- Author(s)
  Kim, J., Motomiya, Y., Ueda, M, Nakamura, M., Misumi, Y., Saito, S., Ikemizu, S., Misumi, S., Ota, K., Shinriki, S., Kai, H., Ando, Y.
- Journal Title
  
  Ann.Clin.Biochem. 45
  
  Pages: 489-495
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370040
[Journal Article] Chromium (III) ion and thyroxine cooperate to stabilize the transthyretin tetramer and suppress in vitro amyloid fibril formation.2006
- Author(s)
  Sato, T., Ando, Y., Susuki, S., Mikami, F., Ikemizu, S., Nakamura, M., Suhr, O., Anraku, M., Kai, T., Suico.M.A., Shuto, T., Mizuguchi, M., Yamagata, Y., Kai, H.
- Journal Title
  
  FEBS Letters 580
  
  Pages: 491-496
- NAID
  120005499991
- Data Source
  KAKENHI-PROJECT-18054025
[Journal Article] Critical YxKxHxxxRP motif in the C-terminal region of GATA3 for its DNA binding and function2006
- Author(s)
  Shinnakasu, R., Yamashita, M., Hosokawa, H., Hasegawa, A., Ikemizu, S., Nakayama, T.
- Journal Title
  
  J. Immunol. 177
  
  Pages: 5801-5810
- Data Source
  KAKENHI-PROJECT-18054025
[Journal Article] Crystal structure and binding properties of the CD2 and CD244 (2B4) binding protein, CD482006
- Author(s)
  Evans, E.J., Castro, M.A.A., O'Brien, R., Kearney, A., Walsh, H., Sparks, L.M., Tucknott, M.G., Davies, E.A., Carmo, A.M., van der Merwe, P.A., Stuart, D.I., Jones, E.Y., Ladbury, J.E., Ikemizu, S., Davis, S.J.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 29309-29320
- Data Source
  KAKENHI-PROJECT-18054025
[Journal Article] Chromium (III) ion and thyroxine cooperate to stabilize the transthyretin tetramer and suppress in vitro amyloid fibril formation.2006
- Author(s)
  Sato, T., Ando, Y., Susuki, S., Mikami, F., Ikemizu, S., Nakamura, M., Suhr, O., Anraku, M., Kai, T., Suico.M.A., Shuto, T., Mizuguchi, M., Yamagata, Y., Kai H.
- Journal Title
  
  FEBS Letters 580
  
  Pages: 491-496
- NAID
  120005499991
- Data Source
  KAKENHI-PROJECT-17053022
[Journal Article] Crystallization and preliminary X-ray analysis of human MTH1 complexed with two oxidized nucleotides, 8-oxo-dGMP and 2-oxo-dATP.2006
- Author(s)
  Nakamura, T., Kitaguchi, Y., Miyazawa, M., Kamiya, H., Toma, S., Ikemizu, S., Shirakawa, M., Nakabeppu, Y., Yamagata, Y.
- Journal Title
  
  Acta Crystallograph. F62
  
  Pages: 1283-1285
- Data Source
  KAKENHI-PROJECT-18054025
[Journal Article] Lactoferrin Glu561Asp Facilitates Secondary Amyloidosis in the Cornea2005
- Author(s)
  Araki-Sasaki, K., Ando, Y., Nakamura, M., Kitagawa, K., Ikemizu, S., Kawaji, T., Yamashita, T., Ueda, M., Hirano, K., Yamada, K., Matsumoto, K., Kinoshita.S., Tanihara.H.
- Journal Title
  
  British J.Ophthalmology 89
  
  Pages: 684-688
- Data Source
  KAKENHI-PROJECT-17053022
[Patent] IL-15とIL-15Rαとの複合体の結晶2007
- Inventor(s)
  池水信二・池鯉鮒麻美
- Industrial Property Rights Holder
  熊本大学
- Filing Date
  2007-04-27
- Data Source
  KAKENHI-PROJECT-18054025
[Presentation] Crystal structure of human oxidative nucleotide hydrolase in complex with a newly found substrate2018
- Author(s)
  Kana Fujimiya, Teruya Nakamura, Yuta Suzuki, Shaimaa Waz, Keisuke Hirata, Mami Chirifu, Shinji Ikemizu, Yuriko Yamagata
- Organizer
  第56回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-16K07276
[Presentation] 免疫タンパク質―受容体の分子認識機構の解明2018
- Author(s)
  池水　信二
- Organizer
  佐賀大学シンクロトロン光応用研究センター講演会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07276
[Presentation] Role of protonation at Asp residues in the broad substrate specificity of human oxidative nucleotide hydrolase2017
- Author(s)
  Teruya Nakamura, Shaimaa Waz, Keisuke Hirata, Mami Chirifu, Shinji Ikemizu, Yuriko Yamagata
- Organizer
  2017 West Coast Protein Crystallography Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07276
[Presentation] カルボン酸の結合距離解析によるhMTH1の基質認識部位のプロトネーション状態の同定2017
- Author(s)
  中村照也、Shaimaa Waz、平田啓介、池鯉鮒麻美、池水信二、山縣ゆり子
- Organizer
  第17回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-16K07276
[Presentation] High resolution and time-resolved X-ray crystallographic study on enzymatic reaction of human MTH12017
- Author(s)
  Teruya Nakamura, Shaimaa Waz, Keisuke Hirata, Mami Chirifu, Shinji Ikemizu, Yuriko Yamagata
- Organizer
  第55回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-16K07276
[Presentation] 幅広い基質特異性を持つ酸化ヌクレオチド加水分解酵素の反応過程の観察2017
- Author(s)
  平田啓介，中村照也，Shaimaa Waz, 池鯉鮒麻，池水信二，山縣ゆり子
- Organizer
  第17回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-16K07276
[Presentation] インターロイキン23のX線結晶構造解析2011
- Author(s)
  四郎園巧, 池鯉鮒麻美, 中村千陽, 中村照也, 山縣ゆり子, 池水信二
- Organizer
  第28回PFシンポジウム
- Place of Presentation
  つくば国際会議場エポカル
- Data Source
  KAKENHI-PUBLICLY-23121523
[Presentation] 機能未知ヒト一回膜貫通型タンパク質のC末ドメインの立体構造に基づく機能解明の試み(1)2010
- Author(s)
  石田智愛, 中村照也, 新堀晶子, 古賀由香里, 池水信二, 甲斐広文, 谷時雄, 山縣ゆり子
- Organizer
  第26回PFシンポジウム
- Place of Presentation
  つくば(つくば国際会議場)
- Data Source
  KAKENHI-PROJECT-20051019
[Presentation] 機能未知ヒト一回膜貫通型タンパク質のC末ドメインの立体構造に基づく機能解明の試み(1)2010
- Author(s)
  石田智愛, 中村照也, 新堀晶子, 古賀由香里, 池水信二, 甲斐広文, 谷時雄, 山縣ゆり子
- Organizer
  第26回PFシンポジウム
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-20370040
[Presentation] ヌクレオシド2リン酸から1リン酸に加水分解する酵素の反応リン酸部位が基質により異なる不思議とその構造的基盤の解明2010
- Author(s)
  有森貴夫、玉置春彦、紙谷浩之、中村照也、池水信二、石橋徹、原島秀吉、関口睦夫、山縣ゆり子
- Organizer
  日本薬学会第130回年会
- Place of Presentation
  岡山(岡山コンベンションセンター)
- Data Source
  KAKENHI-PROJECT-20051019
[Presentation] Crystal Structure of the Glycosylated Form of Interleukin-232010
- Author(s)
  Chirifu, M., Hayashi, C., Nakamura, T., Yamagata, Y., Ikemizu, S.
- Organizer
  3^<rd> International Symposium on Diffraction Structural Biology
- Place of Presentation
  Orsay-France
- Data Source
  KAKENHI-PROJECT-20370040
[Presentation] Structural and NMR analyses revealed unexpected mechanisms of substrate recognition and catalysis by house-cleaning enzymes2010
- Author(s)
  T. Arimori, H. Tamaoki, H. Kamiya, T. Nakamura, S. Ikemizu, T. Ishibashi, H. Harashima, M. Sekiguchi, Y. Yamagata
- Organizer
  The BSR and MASR meetings
- Place of Presentation
  Melbourne, Australia (Melbourne Convention and Exhibition Centre)
- Data Source
  KAKENHI-PROJECT-20051019
[Presentation] 補助刺激分子の構造生物学的研究2010
- Author(s)
  池水信二
- Organizer
  第34回阿蘇シンポジウム
- Place of Presentation
  阿蘇リゾートグランヴィリオホテル
- Data Source
  KAKENHI-PROJECT-20370040
[Presentation] ヌクレオシド2リン酸から1リン酸に加水分解する酵素の反応リン酸部位が基質により異なる不思議とその構造的基盤の解明2010
- Author(s)
  有森貴夫, 玉置春彦, 紙谷浩之, 中村照也, 池水信二, 石橋徹, 原島秀吉, 関口睦夫, 山縣ゆり子
- Organizer
  日本薬学会第130回年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20370040
[Presentation] Structural and NMR analyses revealed unexpected mechanisms of substrate recognition and catalysis by house-cleaning enzymes2010
- Author(s)
  有森貴夫, 玉置春彦, 紙谷浩之, 中村照也, 池水信二, 石橋徹, 原島秀吉, 関口睦夫, 山縣ゆり子
- Organizer
  The BSR and MASR meetings
- Place of Presentation
  Melbourne, Australia
- Data Source
  KAKENHI-PROJECT-20370040
[Presentation] 「サイトカイン制御因子による多様な生体調節」,「IL15およびIL-23の構造生物学的研究」2009
- Author(s)
  池水信二
- Organizer
  第32回日本分子生物学会ワークショップ
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-20370040
[Presentation] ヌクレオシド2リン酸を1リン酸へ加水分解する酵素が異なるリン酸部と反応する不思議とその構造基盤2009
- Author(s)
  有森貴夫, 玉置春彦, 紙谷浩之, 中村照也, 池水信二, 石橋徹, 原島秀吉, 関口睦夫, 山縣ゆり子
- Organizer
  特定領域研究「生体超分子構造」第6回公開シンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20370040
[Presentation] 細胞内浄化酵素ヒトNUDT5の幅広い基質特異性発現機構の解明2009
- Author(s)
  有森貴夫, 玉置春彦, 紙谷浩之, 中村照也, 池水信二, 石橋徹, 原島秀吉関口睦夫, 山縣ゆり子
- Organizer
  第26回薬学会九州支部大会
- Place of Presentation
  福岡(九州大学)
- Data Source
  KAKENHI-PROJECT-20051019
[Presentation] ヌクレオシド2リン酸を1リン酸へ加水分解する酵素が異なるリン酸部と反応する不思議とその構造基盤2009
- Author(s)
  有森貴夫、玉置春彦、紙谷浩之、中村照也、池水信二、石橋徹、原島秀吉、関口睦夫、山縣ゆり子
- Organizer
  特定領域研究「生体超分子構造」第6回公開シンポジウム
- Place of Presentation
  大阪(千里ライフサイエンスセンター)
- Data Source
  KAKENHI-PROJECT-20051019
[Presentation] Mechanistic insight into hydrolysis of oxidized purine nucleotide diphosphates by human NUDT52009
- Author(s)
  有森貴夫, 玉置春彦, 紙谷浩之, 中村照也, 池水信二, 石橋徹, 原島秀吉, 関口睦夫, 山縣ゆり子
- Organizer
  2009 Advanced Science Research Symposium at Fukuoka Dental College
- Place of Presentation
  Fukuoka
- Year and Date
  2009-12-07
- Data Source
  KAKENHI-PROJECT-20370040
[Presentation] IL15およびIL-23の構造生物学的研究2009
- Author(s)
  池水信二
- Organizer
  第32回日本分子生物学会ワークショップ「サイトカイン制御因子による多様な生体調節」
- Place of Presentation
  横浜(パシフィコ横浜)
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-20051019
[Presentation] IL15およびIL-23の構造生物学的研究2009
- Author(s)
  池水信二
- Organizer
  第32回日本分子生物学会ワークショップ「サイトカイン制御因子による多様な生体調節」
- Place of Presentation
  横浜
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-20370040
[Presentation] IL-23の結晶構造解析2009
- Author(s)
  池鯉鮒麻美・林千陽・中村照也・山縣ゆり子・池水信二
- Organizer
  特定領域研究「生体超分子構造」第6回公開シンポジウム
- Place of Presentation
  大阪(千里ライフサイエンスセンター)
- Data Source
  KAKENHI-PROJECT-20051019
[Presentation] IL-23の結晶構造解析2009
- Author(s)
  池鯉鮒麻美・林千陽・中村照也・山縣ゆり子・池水信二
- Organizer
  特定領域研究「生体超分子構造」第5回ワークショップ
- Place of Presentation
  湘南(湘南国際村センター国際会議場)
- Data Source
  KAKENHI-PROJECT-20051019
[Presentation] IL-23の結晶構造解析2009
- Author(s)
  池鯉鮒麻美・林千陽・中村照也・山縣ゆり子・池水信二
- Organizer
  特定領域研究「生体超分子構造」第5回ワークショップ
- Place of Presentation
  湘南
- Data Source
  KAKENHI-PROJECT-20370040
[Presentation] インターロイキン23のX線結晶構造解析2009
- Author(s)
  池鯉鮒麻美・林千陽・中村照也・山縣ゆり子・池水信二
- Organizer
  第9回日本蛋白質科学会年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-20370040
[Presentation] 酸化損傷ヌクレオチド加水分解酵素と新規基質の複合体結晶構造2009
- Author(s)
  有森貴夫, 紙谷浩之, 玉置春彦, 中村照也, 池水信二, 石橋徹, 原島秀吉, 関口睦夫, 山縣ゆり子
- Organizer
  第9回日本蛋白質科学会年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-20370040
[Presentation] 酸化損傷ヌクレオチド加水分解酵素と新規基質の複合体結晶構造2009
- Author(s)
  有森貴夫, 紙谷浩之, 玉置春彦, 中村照也, 池水信二, 石橋徹, 原島秀吉, 関口睦夫, 山縣ゆり子
- Organizer
  第9回日本蛋白質科学会年会
- Place of Presentation
  熊本(熊本全日空ホテルニュースカイ)
- Data Source
  KAKENHI-PROJECT-20051019
[Presentation] 酸化損傷ヌクレオチド加水分解酵素hMTH1の超高分解能結晶の作製と時間分割構造解析による反応過程の追跡2009
- Author(s)
  稲里みゆき, 中村照也, 池水信二, 中別府雄作, 山縣ゆり子
- Organizer
  第26回薬学会九州支部大会
- Place of Presentation
  福岡(九州大学)
- Data Source
  KAKENHI-PROJECT-20051019
[Presentation] IL-23の結晶構造解析2009
- Author(s)
  池鯉鮒麻美・林千陽・中村照也・山縣ゆり子・池水信二
- Organizer
  特定領域研究「生体超分子構造」第6回公開シンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20370040
[Presentation] ヒトNUDT5蛋白質は様々な酸化デオキシリボヌクレオシド二リン酸を分解する2009
- Author(s)
  石田智愛, 中村照也, 新堀晶子, 池水信二, 甲斐広文, 谷時雄, 山縣ゆり子
- Organizer
  特定領域研究「生体超分子構造」第5回ワークショップ
- Place of Presentation
  湘南
- Data Source
  KAKENHI-PROJECT-20370040
[Presentation] 酸化損傷ヌクレオチド加水分解酵素hMTH1の超高分解能結晶の作製と時間分割構造解析による反応過程の追跡2009
- Author(s)
  稲里みゆき, 中村照也, 池水信二, 中別府雄作, 山縣ゆり子
- Organizer
  第26回薬学会九州支部大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20370040
[Presentation] ヒトNUDT5蛋白質は様々な酸化デオキシリボヌクレオシドニリン酸を分解する2009
- Author(s)
  石田智愛, 中村照也, 新堀晶子, 池水信二, 甲斐広文, 谷時雄, 山縣ゆり子
- Organizer
  特定領域研究「生体超分子構造」第5回ワークショップ
- Place of Presentation
  湘南(湘南国際村センター国際会議場)
- Data Source
  KAKENHI-PROJECT-20051019
[Presentation] 細胞内浄化酵素ヒトNUDT5の幅広い基質特異性発現機構の解明2009
- Author(s)
  有森貴夫, 玉置春彦, 紙谷浩之, 中村照也, 池水信二, 石橋徹, 原島秀吉, 関口睦夫, 山縣ゆり子
- Organizer
  第26回薬学会九州支部大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20370040
[Presentation] Mechanistic insight into hydrolysis of oxidized purine nucleotide diphosphates by human NUDT52009
- Author(s)
  T. Arimori, H. Tamaoki, H. Kamiya, T. Nakamura, S. Ikemizu, T. Ishibashi, H. Harashima, M. Sekiguchi, Y. Yamagata
- Organizer
  2009 Advanced Science Research Symposium at Fukuoka Dental College
- Place of Presentation
  Fukuoka (Fukuoka Dental College)
- Year and Date
  2009-12-07
- Data Source
  KAKENHI-PROJECT-20051019
[Presentation] インターロイキン23のX線結晶構造解析2009
- Author(s)
  池鯉鮒麻美・林千陽・中村照也・山縣ゆり子・池水信二
- Organizer
  第9回日本蛋白質科学会年会
- Place of Presentation
  熊本(熊本全日空ホテルニュースカイ)
- Data Source
  KAKENHI-PROJECT-20051019
[Presentation] IL15-IL-15Ra複合体の構造生物学的研究2008
- Author(s)
  池水信二
- Organizer
  平成20年度日本インーターフェロン・サイトカイン学会(奨励賞受賞講演)
- Place of Presentation
  札幌市,北海道大学百年記念会館
- Data Source
  KAKENHI-PROJECT-20370040
[Presentation] 15L15とIL-15Raの分子認識機構の構造生物学的基盤2008
- Author(s)
  池水信二
- Organizer
  BMB2008シンポジウム「シグナル伝達タンパク質の分子認識機構研究の新展開」
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20051019
[Presentation] IL15-IL-15Ra複合体の構造生物学的研究2008
- Author(s)
  池水信二
- Organizer
  平成20年度日本インーターフェロン・サイトカイン学会
- Place of Presentation
  札幌
- Year and Date
  2008-07-12
- Data Source
  KAKENHI-PROJECT-20051019
[Presentation] 免疫蛋白質の分子認識機構2008
- Author(s)
  池水信二
- Organizer
  第5回動脈硬化フォーラム
- Place of Presentation
  佐賀
- Year and Date
  2008-04-28
- Data Source
  KAKENHI-PROJECT-20051019
[Presentation] IL15-IL-15Ra複合体の構造生物学的研究2008
- Author(s)
  池水信二
- Organizer
  平成20年度日本イン-ターフェロン・サイトカイン学会
- Place of Presentation
  札幌
- Year and Date
  2008-07-12
- Data Source
  KAKENHI-PROJECT-20370040
[Presentation] 免疫蛋白質の分子認識機構2008
- Author(s)
  池水信二
- Organizer
  第5回動脈硬化フォーラム
- Place of Presentation
  佐賀
- Year and Date
  2008-04-28
- Data Source
  KAKENHI-PROJECT-20370040
[Presentation] IL15とIL-15Raの分子認識機構の構造生物学的基盤2008
- Author(s)
  池水信二
- Organizer
  BMB2008シンポジウム「シグナル伝達タンパク質の分子認識機構研究の新展開」
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20370040
[Presentation] 「シグナル伝達タンパク質の分子認識機構研究の新展開」,「IL15とIL-15Raの分子認識機構の構造生物学的基盤」2008
- Author(s)
  池水信二
- Organizer
  BMB2008シンポジウム
- Place of Presentation
  神戸市,神戸国際会議場
- Data Source
  KAKENHI-PROJECT-20370040
[Presentation] IL-15/IL-15Rα 複合体の構造生物学的研究2007
- Author(s)
  池水信二
- Organizer
  日本インターフェロン・サイトカイン学会年会
- Place of Presentation
  京都
- Year and Date
  2007-07-05
- Data Source
  KAKENHI-PROJECT-18054025

1. KAI Hirofumi (30194658)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. ARIMA Hidetoshi (50260964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. YAMADA Gen (80174712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. SHUTO Tsuyoshi (80333524)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 山縣ゆり子 (40183678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 土井健史 (00211409)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SUICO Mary Ann (20363525)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 中別府雄作

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. メリー・アンスイコ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 安東由喜雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 山下太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

IKEMIZU SHINJI 池水 信二

IKEMIZU Shinji 池水 信二

Research Projects

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Co-Researchers

Structural basis of the Th1 cell differentiation.Principal Investigator

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T細胞制御機構の構造生物学的基盤Principal Investigator

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Structural studies of immune responses.Principal Investigator

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炎症性サイトカインと受容体の構造生物学的認識機構の解明Principal Investigator

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IL-27の構造生物学的シグナル伝達機構の解明Principal Investigator

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Structural basis of the molecular recognitions involve T cell differentiation.Principal Investigator

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IL-2/IL-2R複合体形成機構の構造生物学的研究Principal Investigator

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IL-2/Il-2R複合体形成機構の構造生物学的基盤Principal Investigator

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補助刺激分子の構造生物学的研究Principal Investigator

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CD28を介した補助刺激の構造を基にしたシグナル伝達機構の解明Principal Investigator

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補助刺激分子のシグナル伝達機構の構造生物学的研究Principal Investigator

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Development of therapeutic ways targeting molecular chaperones and ets transcription factors

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造血幹細胞から巨核球への分化に関わる蛋白質群の3次元構造と機能

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IKEMIZU SHINJI 池水信二

IKEMIZU Shinji 池水信二

[Book] 日本臨牀関節リウマチ(第2版)2010