HONDA Kenya 本田賢也

… Alternative Names

本田賢也ホンダケンヤ

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Researcher Number	60334231
Other IDs
Affiliation (Current)	2025: 慶應義塾大学, 医学部(信濃町), 教授 2025: 国立研究開発法人理化学研究所, 生命医科学研究センター, チームディレクター
Affiliation (based on the past Project Information) *help	2020 – 2025: 慶應義塾大学, 医学部(信濃町), 教授 2018: 慶應義塾大学, 医学部(信濃町), 教授 2015: 国立研究開発法人理化学研究所, 統合生命医科学研究センター, チームリーダー 2015: 慶應義塾大学, 医学部, 教授 2015: 理化学研究所, 統合生命医科学研究センター, チームリーダー … More 2011: The University of Tokyo, 医学(系)研究科(研究院), 准教授 2009 – 2010: The University of Tokyo, 大学院・医学系研究科, 准教授 2009: 東京大学, 大学院・医学系研究科, 助手 2008: Osaka University, 医学系・研究科, 准教授 2007 – 2008: Osaka University, 医学系研究科, 准教授 2004 – 2006: The Univ. of Tokyo, Grad. Sch. of Med, Research Associate, 大学院医学系研究科, 助手 2001 – 2005: 東京大学, 大学院・医学系研究科, 助手 Less
Review Section/Research Field	Principal Investigator Immunology / Biological Sciences / Immunology / Biological Sciences Except Principal Investigator Biological Sciences / General surgery / Cardiovascular medicine / Experimental pathology
Keywords	Principal Investigator 腸内細菌 / サイトカイン / 粘膜免疫 / 樹状細胞 / IRF / Th17細胞 / IL-10 / インターフェロン / 長寿 / 腸炎 … More / 胆汁酸 / トリプシン / がん / 多剤耐性菌 / 常在細 / 百寿 / 抗生物質耐性菌 / 常在細菌 / 代謝疾患 / 大腸がん / ワクチン / 抗生物質耐性 / 錠剤最近 / クロストリジウム / 腸内フローラ / 無菌マウス / ノトバイオート / Treg細胞 / TH17細胞 / 制御性T細胞 / STAT / インターロイキン / イメージング / エンドソーム / クラススイッチ / TLR / 免疫 / ウイルス / TRAF6 / MyD88 / plasmacytoid dendritic cell / ウイルス感染 / IFN / 炎症性サイトカイン / Toll様受容体 / インターフェロン制御因子 … More Except Principal Investigator p53 / インターフェロン / 樹状細胞 / IRFファミリー / アポトーシス / 自然免疫 / Noxa / apoptosis / dendritic cells / IRF family / RANKL / ウイルス感染 / 転写因子 / Toll様受容体 / 発がん抑制 / TLR3 / 抗ウイルス応答 / エフェクターT細胞 / 大腸癌 / 制御性T細胞 / 免疫学 / 細菌 / 循環器・高血圧 / 腸内細菌叢 / 心不全 / 胆汁酸 / モデル動物 / 大腸腫瘍 / ノトバイオート / 大腸発癌 / マウスモデル / 腸内細菌 / antiviral defense / innate immunity / Toll-like receptor / interferon / 炎症性サイトカイン / 形質細胞様樹状細胞 / ウイルス感染防御 / osteoclast / Interferon / IRFファミリー転写因子 / 破骨細胞分化 / シグナルクロストーク / インターフェロン受容体 / Stat1 / RNAKL / 破骨細胞 / IRF / がん / Puma / 適応免疫 / Toll-like receptors / CD8+T細胞 / pathogen-associated molecules / シグナル伝達 / 遺伝子欠損マウス / IRF-7 / IRF-3 / 感染免疫 Less

Unraveling the principles of microbiota function for rationally-designed biotherapeuticsPrincipal Investigator
- Principal Investigator
  
  本田賢也
- Project Period (FY)
  2020 – 2025
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
常在菌Akkermansiaと恒常的宿主免疫応答を決定する細菌ゲノム因子の同定Principal Investigator
- Principal Investigator
  
  本田賢也
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Immunology
- Research Institution
  Keio University
Effect of Intestinal microbiota on inflammation induced colon cancer
- Principal Investigator
  
  Narushima Seiko
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Institute of Physical and Chemical Research
Elucidation of functional role of gut microbiota in heart failure
- Principal Investigator
  
  Akazawa Hiroshi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cardiovascular medicine
- Research Institution
  The University of Tokyo
Development of novel classification of colorectal cancer for immunotherapy
- Principal Investigator
  
  Nishikawa Hiroyoshi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  National Cancer Center Japan
  Osaka University
消化管免疫系の状態を決定する腸内細菌の探索Principal Investigator
- Principal Investigator
  
  本田賢也
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
樹状細胞主導の消化管粘膜バリアー維持機構Principal Investigator
- Principal Investigator
  
  本田賢也
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
  Osaka University
Regulatory signaling in intestinal dendritic cells preventing inflammatory bowel diseasesPrincipal Investigator
- Principal Investigator
  
  HONDA Kenya
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
インターフェロン制御因子ファミリー活性化の時空間ダイナミクスの解析Principal Investigator
- Principal Investigator
  
  本田賢也
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
  The University of Tokyo
Informatory expression system connecting cancer and immunity.
- Principal Investigator
  
  TANIGUCHI Tadatsugu
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
自然免疫系と獲得免疫系の連携における細胞特異的IFN遺伝子発現ネットワークの解析Principal Investigator
- Principal Investigator
  
  本田賢也
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
Functional analyses on roles of intetferon-IRF-family transcriptional factor
- Principal Investigator
  
  TAKAOKA Akinori
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tokyo
感染防御系におけるIFN及びIFN調節因子活性化の役割とその分子基盤の解析
- Principal Investigator
  
  高岡晃教
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
感染免疫システムにおける多様なシグナル伝達経路の活性化とその意義に関する研究
- Principal Investigator
  
  高岡晃教
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
感染免疫システムにおける多様なシグナル伝達経路の活性化とその意義に関する研究
- Principal Investigator
  
  TAKAOKA Akinori
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Gene expression network for tumor suppression
- Principal Investigator
  
  TANIGUCHI Tadatsugu
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo

[Book] 免疫応答と免疫病態の統合的分子理解…免疫系細胞における遺伝子発現の時空間制御2007
- Author(s)
  本田賢也, ら
- Total Pages
  269
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-19390137
[Book] 「免疫系細胞における遺伝子発現の時空間制御」[免疫応答と免疫病態の統合的分子理解](谷口維紹、山本一彦編)2007
- Author(s)
  本田賢也
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-19390137
[Book] 免疫応答と免疫病態の統合的分子理解…免疫系細胞における遺伝子発現の時空間制御2007
- Author(s)
  本田賢也, ら
- Total Pages
  269
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-18060008
[Journal Article] Centenarians have a diverse gut virome with the potential to modulate metabolism and promote healthy lifespan2023
- Author(s)
  Johansen Joachim、Atarashi Koji、Arai Yasumichi、Hirose Nobuyoshi、Sorensen Soren J.、Vatanen Tommi、Knip Mikael、Honda Kenya、Xavier Ramnik J.、Rasmussen Simon、Plichta Damian R.
- Journal Title
  
  Nature Microbiology
  
  Volume: 8 Issue: 6 Pages: 1064-1078
- DOI
  10.1038/s41564-023-01370-6
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05627, KAKENHI-PROJECT-23K27654
[Journal Article] Diet-mediated constitutive induction of novel IL4+ ILC2 cells maintains intestinal homeostasis in mice2023
- Author(s)
  Cui Wanlin, Nagano Yuji, Hatakeyama Masanori, Honda Kenya , et al.
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: － Issue: 8
- DOI
  10.1084/jem.20221773
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04804, KAKENHI-PROJECT-22K19422, KAKENHI-PROJECT-20H05627, KAKENHI-PLANNED-22H05191, KAKENHI-PROJECT-22H04995, KAKENHI-PROJECT-20H00504, KAKENHI-PROJECT-21H04801, KAKENHI-PROJECT-23K27654
[Journal Article] The effects of oral microbiota on health2022
- Author(s)
  Tuganbaev Timur、Yoshida Koji、Honda Kenya
- Journal Title
  
  Science
  
  Volume: 376 Issue: 6596 Pages: 934-936
- DOI
  10.1126/science.abn1890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H05627
[Journal Article] Microbiota imbalance induced by dietary sugar disrupts immune-mediated protection from metabolic syndrome2022
- Author(s)
  Kawano Yoshinaga、＿＿＿＿、Honda Kenya (13人中12番目）、Ivanov Ivaylo I.
- Journal Title
  
  Cell
  
  Volume: 185 Issue: 19 Pages: 3501-3519.e20
- DOI
  10.1016/j.cell.2022.08.005
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05627
[Journal Article] T Cell Responses to the Microbiota2022
- Author(s)
  Ivanov Ivaylo I.、Tuganbaev Timur、Skelly Ashwin N.、Honda Kenya
- Journal Title
  
  Annual Review of Immunology
  
  Volume: 40 Issue: 1 Pages: 559-587
- DOI
  10.1146/annurev-immunol-101320-011829
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H05627
[Journal Article] Identification of trypsin-degrading commensals in the large intestine2022
- Author(s)
  Li Youxian (32名中1番目）、___、Honda Kenya (32名中32番目）
- Journal Title
  
  Nature
  
  Volume: 609 Issue: 7927 Pages: 582-589
- DOI
  10.1038/s41586-022-05181-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05627
[Journal Article] Targeted suppression of human IBD-associated gut microbiota commensals by phage consortia for treatment of intestinal inflammation2022
- Author(s)
  Federici Sara、＿＿＿、Honda Kenya (53人中45番目）、＿＿＿、Elinav Eran
- Journal Title
  
  Cell
  
  Volume: 185 Issue: 16 Pages: 2879-2898.e24
- DOI
  10.1016/j.cell.2022.07.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05627
[Journal Article] Non‐zero‐sum microbiome immune system interactions2021
- Author(s)
  Tuganbaev Timur、Honda Kenya
- Journal Title
  
  European Journal of Immunology
  
  Volume: 51 Issue: 9 Pages: 2120-2136
- DOI
  10.1002/eji.202049065
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05627
[Journal Article] Toward the development of defined microbial therapeutics2021
- Author(s)
  Li Youxian、Honda Kenya
- Journal Title
  
  International Immunology
  
  Volume: 33 Issue: 12 Pages: 761-766
- DOI
  10.1093/intimm/dxab038
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05627
[Journal Article] Staphylococcus cohnii is a potentially biotherapeutic skin commensal alleviating skin inflammation2021
- Author(s)
  Ito Y, Sasaki T, Li Y, et al
- Journal Title
  
  Cell Reports
  
  Volume: 35 Issue: 4 Pages: 109052-109052
- DOI
  10.1016/j.celrep.2021.109052
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04954, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-20H05627, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-20H00495, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-21H02394, KAKENHI-PROJECT-21K08308
[Journal Article] Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians2021
- Author(s)
  Yuko Sato, Koji Atarashi, Damian R. Plichta, Yasumichi Arai, Satoshi Sasajima, SM. Kearney, Kozue Takeshita, AN. Skelly, Youxian Li, Takeshi Tanoue, Seiko Narushima, DR. Littman, MA. Fischbach, Y Uwamino, T Inoue, A Honda, Masahira Hattori, Tsuyoshi Murai, Ramnik J. Xavier, Nobuyoshi Hirose, Kenya Honda, et al.
- Journal Title
  
  Nature
  
  Volume: 599 Issue: 7885 Pages: 458-464
- DOI
  10.1038/s41586-021-03832-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05627, KAKENHI-PROJECT-20H00535, KAKENHI-PROJECT-18H03055, KAKENHI-PROJECT-21K08584, KAKENHI-PROJECT-21K18270
[Journal Article] Mining the microbiota for microbial and metabolite-based immunotherapies2019
- Author(s)
  Skelly Ashwin N.、Sato Yuko、Kearney Sean、Honda Kenya
- Journal Title
  
  Nature Reviews Immunology
  
  Volume: 印刷中 Issue: 5 Pages: 305-323
- DOI
  10.1038/s41577-019-0144-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18F18104
[Journal Article] Induction of Th17 cells by segmented filamentous bacteria in the murine intestine2015
- Author(s)
  Farkas AM, Panea C, 後藤義幸, 中藤学, Galan-Diez M, 成島聖子, 本田賢也, Ivanov II
- Journal Title
  
  J Immunol Methods
  
  Volume: 421 Pages: 104-111
- DOI
  10.1016/j.jim.2015.03.020
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06159, KAKENHI-PROJECT-26670194
[Journal Article] Induction of colonic regulatory T cells by indigenous Clostridium species2011
- Author(s)
  Koji Atarashi, Takeshi Tanoue, 他14名, Kenya Honda
- Journal Title
  
  Science
  
  Volume: 331 Pages: 337-341
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390150
[Journal Article] Immune responses to gut microbiota-commensals and pathogens.2010
- Author(s)
  Takeshi Tanoue, Yoshinori Umesaki, Kenya Honda
- Journal Title
  
  Gut Microbes
  
  Volume: 1 Pages: 224-233
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390150
[Journal Article] Regulatory mechanisms of immune responses to intestinal bacteria2009
- Author(s)
  Honda K, Takeda K.
- Journal Title
  
  Mucosal Immunol 2
  
  Pages: 187-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390137
[Journal Article] Induction of intestinal Th17 cells by segmented filamentous bacteria.2009
- Author(s)
  Ivanov II, Atarashi K, 他13名, Honda K, Littman DR.
- Journal Title
  
  Cell 30
  
  Pages: 485-498
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390150
[Journal Article] NFATc1 mediates Toll-like receptor-independent innate immune responses during Trypanosoma cruzi infection2009
- Author(s)
  Kayama H, 他8名, Honda K, Yamamoto M, Takeda K.
- Journal Title
  
  PLoS Pathog. 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057013
[Journal Article] Hematopoietic cell derived interferon controls viral replication and virus induced disease2009
- Author(s)
  Lang PA, Cervantes-Barragan L, Verschoor A, Navarini AA, Recher M, Pellegrini M, Flatz L, Bergthaler A, Honda K, Ludewig B, Ohashi PS, Lang KS
- Journal Title
  
  Blood 113
  
  Pages: 1045-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390137
[Journal Article] A selective contribution of the RIG-I-like receptor pathway to type I interferon responses activated by cytosolic DNA.2009
- Author(s)
  Choi MK, Wang Z, Ban T, Yanai H, Lu Y, Koshiba R, Nakaima Y, Hangai S, Savitsky D, Nakasato M, Negishi H, Takeuchi O, Honda K, Akira S, Tamura T, Taniguchi T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA Vol.106
  
  Pages: 17870-17875
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Triggering TLR7 in mice induces immune activation and lymphoid system disruption, resembling HIV-mediated pathology2009
- Author(s)
  Baenziger S, Heikenwalder M, Johansen P, Schlaepfer E, Hofer U, Miller RC, Diemand S, Honda K, Kundig TM, Aguzzi A, Speck RF
- Journal Title
  
  Blood 113
  
  Pages: 377-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390137
[Journal Article] Induction of intestinal Th17 cells by segmented filamentous bacteria2009
- Author(s)
  Ivanov II, Atarashi K, 他3名, Honda K, Littman DR.
- Journal Title
  
  Cell 30
  
  Pages: 485-498
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057013
[Journal Article] HMGB proteins function as universal sentinels for nucleic acid-mediated innate immune responses.2009
- Author(s)
  Yanai H, Ban T, Wang Z, Choi MK, Kawamura T, Negishi H, Nakasato M, Lu Y, Hangai S, Koshiba R, Savitsky D, Ronfani R, Akira S, Bianchi ME, Honda K, Tamura T, Kodama T, Taniguchi T.
- Journal Title
  
  Nature Vol.462
  
  Pages: 99-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] NFATc1 mediates Toll-like receptor-independent innate immune responses during Trypanosoma cruzi infection.2009
- Author(s)
  Kayama H, 他8名, Honda K, Yamamoto M, Takeda K.
- Journal Title
  
  PLoS Pathog. 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390150
[Journal Article] The contribution of transcription factor IRF1 to the interferon-gamma-interleukin 12 signaling axis and T(H)1 versus T(H)-17 differentiation of CD4(+) T cells2008
- Author(s)
  Kano SI., Sato K., Morishita Y., Vollstedt S., Kim S., Bishop K., Honda K., Kubo M., Taniguchi T.
- Journal Title
  
  Nature Immunology 9
  
  Pages: 34-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390137
[Journal Article] Homeostatic erythropoiesis by the transcription factor IRF2 through attenuation of type I interferon signaling.2008
- Author(s)
  Mizutani T, Tsuji K, Ebihara Y, Taki S, Ohba Y, Taniguchi T, Honda K.
- Journal Title
  
  Exp. Hematol. Vol.36
  
  Pages: 255-264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] ATP drives lamina propria T(H)17 cell differentiation2008
- Author(s)
  Atarashi K,(他8名), Honda K, Takeda K.
- Journal Title
  
  Nature 455
  
  Pages: 808-812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057013
[Journal Article] ATP drives lamina propria T(H)17 cell differentiation2008
- Author(s)
  Atarashi K, Nishimura J, Shima T, Umesaki Y, Yamamoto M, Onoue M, Yagita H, Ishii N, Evans R, Honda K, Takeda K.
- Journal Title
  
  Nature 455
  
  Pages: 808-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390137
[Journal Article] The contribution of transcription factor IRF1 to the interferon-gamma-interleukin 12 signaling axis and T(H)1 versus T(H)-17 differentiation of CD4(+) T cells.2008
- Author(s)
  Kano S, Sato K, Morishita Y, Vollstedt S, Kim S, Bishop K, Honda K, Kubo M, Taniguchi T.
- Journal Title
  
  Nat. Immunol. Vol.9
  
  Pages: 34-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Inefficient phagosome maturation in infant macrophages2008
- Author(s)
  Saito F, Kuwata H, Oiki E, Koike M, Uchiyama Y, Honda K, Takeda K.
- Journal Title
  
  BBRC 375
  
  Pages: 113-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390137
[Journal Article] A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity2008
- Author(s)
  Negishi H, Osawa T, Ogami K, Ouyang X, Sakaguchi S, Koshiba R, Yanai H, Seko Y, Shitara H, Bishop K, Yonekawa H, Tamura T, Kaisho T, Taya C, Taniguchi T, Honda K
- Journal Title
  
  PNAS 105
  
  Pages: 20446-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390137
[Journal Article] A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity.2008
- Author(s)
  Negishi H, Osawa T, Ogami K, Ouyang X, Sakaguchi S, Koshiba R, Yanai H, Seko Y, Shitara H, Bishop K, Yonekawa H, Tamura T, Kaisho T, Taya C, Taniguchi T, Honda K.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA Vol.105
  
  Pages: 20446-20451
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] ATP drives lamina propr ia T(H)17 cell differentiation.2008
- Author(s)
  Atarashi K, (他8名), Honda K, Takeda K.
- Journal Title
  
  Nature 455
  
  Pages: 808-812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390137
[Journal Article] Homeostatic erythropoiesis by the transcription factor IRF2 through attenuation of type I interferon signaling2008
- Author(s)
  Mizutani, T., K. Tsuji, Y. Ebihara, S. Taki, Y. Ohba, T. Taniguchi, K. Honda
- Journal Title
  
  Exp Hematol 36
  
  Pages: 255-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390137
[Journal Article] Lipocalin 2-dependent inhibition of mycobacterial growth in alveolar epithelium2008
- Author(s)
  Saiga H, Nishimura J, Kuwata H, Okuyama M, Matsumoto S, Sato S, Matsumoto M, Akira S, Yoshikai Y, Honda K, Yamamoto M, Takeda K
- Journal Title
  
  J Immunol 181
  
  Pages: 8521-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390137
[Journal Article] Class-specific Regulation of Pro-inflammatory Genes by MyD88 Pathways and IkBz2008
- Author(s)
  Kayama H, Ramirez-Carrozzi VR, Yamamoto M, Mizutani T, Kuwata H, Iba H, Matsumoto M, Honda K, Smale ST, Takeda K
- Journal Title
  
  J Biol Chem 283
  
  Pages: 12468-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390137
[Journal Article] A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity.2008
- Author(s)
  Negi shi H, (他14名), HondaK.
- Journal Title
  
  Proc Natl Acad Sci U S A. 105
  
  Pages: 20446-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390137
[Journal Article] DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response.2007
- Author(s)
  Takaoka A, Wang Z, Choi MK, Yanai H, Negishi H, Ban T, Lu Y, Miyagishi M, Kodama T, Honda K, Ohba Y, Taniguchi T.
- Journal Title
  
  Nature Vol.448
  
  Pages: 501-505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Pole of IFN regulatory factor 5 transcription factor in anitiviral immunity and tumor suppression.2007
- Author(s)
  Yanai H, Chen HM, Inuzaka T, Koado S, Mak TW, Takaoka A, Honda K, Taniguchi T.
- Journal Title
  
  Proc Natl Acad Sci U S A. 104
  
  Pages: 3402-3407
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression.2007
- Author(s)
  Yanai H., Chen H., Inuzuka T., Kondo S., Mak WT., Takaoka A., Honda K. Taniguchi T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA Vol.104
  
  Pages: 3402-3407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression.2007
- Author(s)
  Yanai, H., Chen, H.M., Inuzuka, T., Kondo, S., Mak, T.W., Takaoka, A., Honda, K., Taniguchi, T.
- Journal Title
  
  Proc Natl Acad sci USA 104巻
  
  Pages: 3402-3407
- Data Source
  KAKENHI-PROJECT-18060008
[Journal Article] DAI(DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response2007
- Author(s)
  Takaoka A, Wang Z, Choi MK, Yanai H, Negishi H, Ban T, Lu Y, Miyagishi M, Kodama T, Honda K, Ohba Y, Taniguchi T
- Journal Title
  
  Nature 448
  
  Pages: 501-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390137
[Journal Article] Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression.2007
- Author(s)
  Yanai, H., Chen, H., Inuzuka, T., Kondo, S., Mak, W.T., Takaoka.A., Honda, K., Taniguchi, T.
- Journal Title
  
  PNAS 104
  
  Pages: 3402-3407
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression.2007
- Author(s)
  Yanai, H., Chen, H.M., Inuzuka, T., Kondo, S., Mak, Takaoka, A., Honda, K., Taniguchi, T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 104
  
  Pages: 3402-3407
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] Cooperation between MyD88 and TRIF pathways in TLR synergy via IRF5 activation.2007
- Author(s)
  Ouyang, X., Negishi, H., Takeda, R., Fujita, Y., Taniguchi, T., Honda, K.
- Journal Title
  
  Biochem Biophys Res Commun 354巻
  
  Pages: 1045-1051
- Data Source
  KAKENHI-PROJECT-18060008
[Journal Article] IRFs : master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors.2006
- Author(s)
  Honda, K., Taniguchi, T.
- Journal Title
  
  Nat Rev Immunol 6巻
  
  Pages: 644-658
- Data Source
  KAKENHI-PROJECT-18060008
[Journal Article] IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors.2006
- Author(s)
  Honda K, Taniguchi T.
- Journal Title
  
  Nat. Rev. Immunol. Vol.6
  
  Pages: 644-659
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] IRFs : master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors.2006
- Author(s)
  Honda, K., Taniguchi, T.
- Journal Title
  
  Nature Rev. Immunol. 6
  
  Pages: 644-658
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Toll-like receptor signaling and IRF transcription factors.2006
- Author(s)
  Honda, K., Taniguchi, T.
- Journal Title
  
  IUBMB Life 58巻
  
  Pages: 290-295
- Data Source
  KAKENHI-PROJECT-18060008
[Journal Article] Evidence for licensing of IFN- γ -induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program.2006
- Author(s)
  Negishi, H., Fujita, Y., Yanai, H., Sakaguchi, S., Ouyang, X., Shinohara, M., Takayanagi, H., Ohba, Y., Taniguchi, T., Honda, K.
- Journal Title
  
  Proc. Natl. Acad. Sci. 103
  
  Pages: 15136-15141
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Evidence for licensing of IFN-γ-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program.2006
- Author(s)
  Negishi, H, Fujita, Y, Yanai, H, Sakaguchi, S, Ouyang, X, Shinohara, M, Takayanagi, H, Ohba, Y, Taniguchi, T, Honda, K
- Journal Title
  
  Proc Natl Acad Sci USA 103巻
  
  Pages: 15136-15141
- Data Source
  KAKENHI-PROJECT-18060008
[Journal Article] Type I interferon gene induction by the interferon regulatory factor family of transcription factors.2006
- Author(s)
  Honda, K., Takaoka, A., Taniguchi, T.
- Journal Title
  
  Immunity 25巻
  
  Pages: 349-360
- Data Source
  KAKENHI-PROJECT-18060008
[Journal Article] Evidence for licensing of IFN-γ-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program.2006
- Author(s)
  Negishi H, Fujita Y, Yanai H, Sakaguchi S, Ouyang X, Shinohara M, Takayanagi H, Ohba Y, Taniguchi T, Honda K.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA Vol.103
  
  Pages: 15136-15141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors.2005
- Author(s)
  Takaoka, A., Yanai, H., Kondo, S., Duncan, G., Negishi, H., Mizutani, T., Kano, S., Honda, K., Ohba, Y., Mak, T.M., Taniguchi, T.
- Journal Title
  
  Nature Vol. 434, No 7030
  
  Pages: 243-249
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219204
[Journal Article] Regulation of the type 1 IFN induction : a current view.2005
- Author(s)
  Honda, K., Yanai, H., Takaoka, A., Taniguchi T.
- Journal Title
  
  Int.Immunol. 17
  
  Pages: 1367-1378
- Data Source
  KAKENHI-PROJECT-16790284
[Journal Article] Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction.2005
- Author(s)
  Honda, K., Ohba, Y., Yanai, H., Negishi, H., Mizutani, T., Takaoka, A., Taya, C., Taniguchi, T.
- Journal Title
  
  Nature Vol.434
  
  Pages: 1035-1040
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] Negative regulation of Toll-like-receptor signaling by IRF-4.2005
- Author(s)
  Negishi H, Ohba Y, Yanai H, Takaoka A, Honma K, Yui K, Matsuyama T, Taniguchi T, Honda K.
- Journal Title
  
  Proc Natl Acad Sci U S A. 102
  
  Pages: 15989-15994
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] IRF-7 is the master regulator of type-1 interferon-dependent immune responses.2005
- Author(s)
  Honda, K., Yanai, H., Negishi, H., Asagiri, M., Sato, M., Mizutani, T., Shimada, N., Ohba, Y., Takaoka, A., Yoshida, N., Taniguchi, T
- Journal Title
  
  Nature 434
  
  Pages: 772-777
- Data Source
  KAKENHI-PROJECT-16790284
[Journal Article] Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors2005
- Author(s)
  Takaoka A., Yanai H., Kondo S., Duncan G., Negishi H., Mizutani T., Kano S., Honda K., Ohba Y., Mak T.M., Taniguchi T.
- Journal Title
  
  Nature 434
  
  Pages: 243-249
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] IRF-7 is the master regulator of type-I interferon-dependent immune responses.2005
- Author(s)
  Honda K, Yanai H, Negishi H, Asagiri M, Sato M, Mizutani T, Shimada N, Ohba Y, Takaoka A, Yoshida N, Taniguchi T.
- Journal Title
  
  Nature Vol.434
  
  Pages: 772-777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Spatiotemporal regulation of MyD88-IRF-7 signaling for robust type I interferon induction.2005
- Author(s)
  Honda K., Ohba, Y., Yanai, H., Negishi, H., Mizutani, T., Takaoka, A., Taya, C., Taniguchi, T.
- Journal Title
  
  Nature Vol 434
  
  Pages: 1035-1040
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12219204
[Journal Article] Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors2005
- Author(s)
  Takaoka A., Yanai H., Kondo S., Duncan G., Negishi H., Mizutani T., Kano S., Honda K., Ohba Y., Mak T.M., Taniguchi T.
- Journal Title
  
  Nature Vol.434
  
  Pages: 243-249
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Integral role of IRF-5 in the gene nduction programme activated by Toll-like receptors.2005
- Author(s)
  Takaoka, A., Yanai, H., Kondo, S., Duncan, G., Negishi, Mizutani, T., Kano, S., Honda, K., Ohba, Y., Mak, T.M., Taniguchi, T.
- Journal Title
  
  Nature 434
  
  Pages: 243-249
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] IRF-7 is the master regulator of type-I interferon-dependent immune responses.2005
- Author(s)
  Honda K., Yanai H., Negishi H., Asagiri M., Sato M., Mizutani T., Shimada N., Ohba Y., Takaoka A., Yoshida N., Taniguchi T.
- Journal Title
  
  Nature Vol 434, No. 7034
  
  Pages: 772-777
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219204
[Journal Article] Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction2005
- Author(s)
  Honda, K., Ohba, Y., Yanai, H., Negishi, H., Mizutani, T., Takaoka, A., Taya, C., Taniguchi, T.
- Journal Title
  
  Nature 434
  
  Pages: 1035-1040
- Data Source
  KAKENHI-PROJECT-16790284
[Journal Article] Negative regulation of Toll-like receptor signaling by IRF-42005
- Author(s)
  Negishi, H., Ohba, Y., Yanai, H., Takaoka, A., Honma, K., Yui, K., Matsuyama, T., Taniguchi, T., Honda, K.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA. Vol.102
  
  Pages: 15989-15994
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] IRF-7 is the master regulator of type-I interferon-dependent immune responses2005
- Author(s)
  Honda, K., Yanai, H., 他9名
- Journal Title
  
  Nature 434
  
  Pages: 772-777
- Data Source
  KAKENHI-PROJECT-16790284
[Journal Article] Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors.2005
- Author(s)
  Takaoka.A., Yanai, H., Kondo, S., Duncan, G., Negishi, H., Mizutani, T., Kano, S., Honda, K., Ohba, Y, Mak, T.M., Taniguchi, T.
- Journal Title
  
  Nature 434・7030
  
  Pages: 243-249
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors.2005
- Author(s)
  Takaoka, A., Yanai, H., Kondo, S., Duncan, G., Negishi, H., Mizutani, T., Kano, S., Honda, K., Ohba, Y., Mak, T.M., Taniguchi, T.
- Journal Title
  
  Nature Vol.434
  
  Pages: 243-249
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors.2005
- Author(s)
  Takaoka A, Yanai H, Kondo S, Duncan G, Negishi H, Mizutani T, Kano S, Honda K, Ohba Y, Mak TM, Taniguchi T.
- Journal Title
  
  Nature Vol.434
  
  Pages: 243-249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Negative regulation of Toll-like receptor signaling by IRF-4.Proc.Natl.Acad.Sci.USA.2005
- Author(s)
  Negishi, H., Ohba, Y., Yanai, H., Takaoka, A., Honma, K., Yui, K., Matsuyama, T., Taniguchi, T., Honda, K.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA. Vol.102
  
  Pages: 15989-15994
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] Negative regulation of Toll-like receptor signaling by IRF-4.2005
- Author(s)
  Negishi, H., Ohba, Y., Yanai, H., Takaoka, A., Honma, K., Yui, K., Matsuyama, T., Taniguchi, T., Honda, K.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 102
  
  Pages: 15989-15994
- Data Source
  KAKENHI-PROJECT-16790284
[Journal Article] Regulation of the type I IFN induction : a current view2005
- Author(s)
  Honda, K., Yanai, H., Takaoka, A., Taniguchi, T.
- Journal Title
  
  Int.Immunol Vol.17
  
  Pages: 367-1378
- NAID
  10020560939
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Negative regulation of Toll-like-receptor signaling by IRF-4.2005
- Author(s)
  Negishi, H., Ohba, Y., Yanai, H., Takaoka, A., Honma, Yui, K., Matsuyama, T., Taniguchi, T., Honda, K.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 120
  
  Pages: 15989-15994
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction.2005
- Author(s)
  Honda K., Ohba, Y., Yanai, H., Negishi H., Mizutani, T., Takaoka, A., Taya, C., Taniguchi, T
- Journal Title
  
  Nature 434
  
  Pages: 1035-1040
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] IRF-7 is the master regulator of type-I interferon-dependent immune responses.2005
- Author(s)
  Honda, K., Yanai, H., Negishi, H., Asagiri, M., Sato, M., Mizutani, T., Shimada, N., Ohba, Y., Takaoka, A., Yoshida, N., Taniguchi, T.
- Journal Title
  
  Nature Vol.434
  
  Pages: 772-777
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] Spatiotemporal regulation of MmyD88-IRF-7 signalling for robust type I interferon induction.2005
- Author(s)
  Honda K, Ohba Y, Yanai H, Negishi H, Mizutani T, Takaoka A, Taya C, Taniguchi T.
- Journal Title
  
  Nature Vol.434
  
  Pages: 1035-1040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Regulation of the type I IFN induction: a current view.2005
- Author(s)
  Honda K, Yanai H, Takaoka A, Taniguchi T.
- Journal Title
  
  Int. Immunol. Vol.17
  
  Pages: 1367-1378
- NAID
  10020560939
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type I nterferon induction.2005
- Author(s)
  Honda, K., Ohba, Y., Yanai, H., Negishi, H., Mizutani, T., Takaoka, A., Taya, C., Taniguchi, T.
- Journal Title
  
  Nature 434
  
  Pages: 1035-1040
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] IRF-7 is the masterregulator of type-I interferon-dependent immune responses.2005
- Author(s)
  Honda K., Yanai H., Negishi H., Asagiri M., Sato M., Mizutani T., Shimada N., Ohba Y., Takaoka A., Yoshida N., Taniguchi T.
- Journal Title
  
  Nature Vol 434, No. 7034
  
  Pages: 772-777
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12219204
[Journal Article] IRF-7 is the master regulator of type-I interferon-dependent immune responses.2005
- Author(s)
  Honda, K., Yanai, H., Negishi, H., Asagiri, M., Sato, M., Mizutani, T., Shimada, N., Ohba, Y., Takaoka, A., Yoshida, N., Taniguchi, T.
- Journal Title
  
  Nature 434
  
  Pages: 727-777
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] Negative regulation of Toll-like-receptor signaling by IRF-4.2005
- Author(s)
  Negishi H, Ohba Y, Yanai H, Takaoka A, Honma K, Yui K, Matsuyama T, Taniguchi T, Honda K.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA Vol.102
  
  Pages: 15989-15994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors.2005
- Author(s)
  Takaoka, A., Yanai, H., Kondo, S., Duncan, G., Negishi, H., Mizutani, T., Kano, S., Honda, K., Ohba, Y., Mak, T.M., Tanigichi, T.
- Journal Title
  
  Nature (in press)
- Data Source
  KAKENHI-PROJECT-12219204
[Journal Article] Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type I interferon induction2005
- Author(s)
  Honda K., Ohba, Y., Yanai, H., Negishi, H., Mizutani, T., Takaoka, A., Taya C., Taniguchi, T.
- Journal Title
  
  Nature Vol 434
  
  Pages: 1035-1040
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219204
[Journal Article] Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling.2004
- Author(s)
  Honda, K., Yanai, H., 他8名
- Journal Title
  
  Proc.Natl Acad.Sci.USA 101巻・43号
  
  Pages: 15416-15421
- Data Source
  KAKENHI-PROJECT-16790284
[Journal Article] Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling.2004
- Author(s)
  Honda, K., Yanai, H., Mizutani, T., Negishi, H., Shimada, N., Suzuki, N., Ohba, Y., Takaoka, A., Wen-Chen Yeh, Taniguchi, T
- Journal Title
  
  Proc.Natl.Acad.Sci.USA vol.101, no.43
  
  Pages: 15416-15421
- Data Source
  KAKENHI-PROJECT-12219204
[Journal Article] Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling.2004
- Author(s)
  Honda, K., Yanai, H, Mizutani, T, Negishi, H., Shimada, N, Suzuki, N, Obba, Y, Takaoka.A., Wen-Chen Yeh, Taniguchi, T.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 101・43
  
  Pages: 15416-15421
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] Negative regulation of IFN-α/β signaling by IFN regulatory factor 2 for homeostatic development of dendritic cells.2004
- Author(s)
  Honda K., Mizutani, T, Taniguchi, T.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA vol.101
  
  Pages: 2416-2421
- Data Source
  KAKENHI-PROJECT-12219204
[Journal Article] Negative regulation of IFN-α/β signaling by IFN regulatory factor 2 for homeostatic development of dendritic cells.2004
- Author(s)
  Honda, K., Mizutani, T., Taniguchi, T
- Journal Title
  
  Proc.Natl Acad.Sci.USA 101巻・8号
  
  Pages: 2416-2421
- Data Source
  KAKENHI-PROJECT-16790284
[Journal Article] Integration of IFN-α/β sinalling to p53 responses in tumour suppression and anitiviral defense.2003
- Author(s)
  Takaoka, A., Hayakawa, S., Yanai, H., Stoiber, D., Negishi H., Kikuchi, H., Sasaki, S., Imai, K., Shibue, T., Honda, K., Taniguchi, T.
- Journal Title
  
  Nature 424
  
  Pages: 516-526
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] Integration of IFN-a/f3 signalling to p53 responses in tumour suppression and antiviral defense.2003
- Author(s)
  Takaoka, A., Hayakawa, S., Yanai, H., Stoiber, D., Negishi, H., Kikuchi, H., Sasaki, S., Imai, K., Shibue, T., Honda, K., Taniguchi, T.
- Journal Title
  
  Nature 424
  
  Pages: 516-526
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16017220
[Patent] グルコン酸消費菌を有効成分とする抗菌組成物2023
- Inventor(s)
  古市宗弘本田賢也　ほか
- Industrial Property Rights Holder
  古市宗弘本田賢也　ほか
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Overseas
- Data Source
  KAKENHI-PROJECT-20H05627
[Patent] トリプシン又はＴＭＰＲＳＳ２の分解用組成物2023
- Inventor(s)
  Youxian Li, 本田賢也　ほか
- Industrial Property Rights Holder
  Youxian Li, 本田賢也　ほか
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-576680
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-20H05627
[Patent] トリプシン又はＴＭＰＲＳＳ２の分解用組成物2022
- Inventor(s)
  Youxian Li, 本田賢也　ほか
- Industrial Property Rights Holder
  Youxian Li, 本田賢也　ほか
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-20H05627
[Patent] 100歳以上の長寿者に特有の胆汁酸代謝菌の同定およびその代謝経路の解析2021
- Inventor(s)
  本田賢也, 新幸二, 佐藤優子
- Industrial Property Rights Holder
  本田賢也, 新幸二, 佐藤優子
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-20H05627
[Presentation] 腸内細菌と長寿2023
- Author(s)
  新　幸二、本田　賢也
- Organizer
  第46回日本神経科学大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H05627
[Presentation] Toward development of defined microbial therapeutics2023
- Author(s)
  本田　賢也
- Organizer
  7th Microbiome R&D and Business Collaboration Congress: Asia
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05627
[Presentation] Human Microbiota Regulation of Barrier Immunity2023
- Author(s)
  本田　賢也
- Organizer
  KEYSTONE SYMPOSIA on Molecular and Cellular Biology Regulation of Barrier Immunity (X8)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05627
[Presentation] Microbiome and Immunity: Role in Cancer2023
- Author(s)
  本田　賢也
- Organizer
  KEYSTONE SYMPOSIA on Molecular and Cellular Biology Microbiota and Cancer Immunity (K2)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05627
[Presentation] Toward the development of defined microbial therapeutics2023
- Author(s)
  本田　賢也
- Organizer
  EMBO | EMBL Symposium: The human microbiome
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05627
[Presentation] Harness connections between the microbiome and disease to improve human health2023
- Author(s)
  本田　賢也
- Organizer
  第41回札幌国際がんシンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05627
[Presentation] Toward the development of defined microbial therapeutics2023
- Author(s)
  本田　賢也
- Organizer
  The 21st Awaji International Forum on Infection and Immunity
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05627
[Presentation] Toward development of defined microbial therapeutics2023
- Author(s)
  Kenya Honda
- Organizer
  Global Immunotalks
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05627
[Presentation] Interspecies communication for structuring homeostatic microbiota2022
- Author(s)
  Kenya Honda
- Organizer
  IHMC2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05627
[Presentation] Toward the development of defined microbial therapeutics2022
- Author(s)
  Kenya Honda
- Organizer
  Microbiome Virtual International Forum
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05627
[Presentation] Microbiota and regulation of intestinal immunity2021
- Author(s)
  本田賢也
- Organizer
  The 2021 Principles of Mucosal Immunology course, Society for mucosal Immunology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05627
[Presentation] Identifying effector microbes that causally affect the host physiology to develop defined microbial therapeutics2021
- Author(s)
  本田賢也
- Organizer
  The 10th Microbiome Interactions in Health and Disease meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05627
[Presentation] Mining the microbiota and identifying effector microbes that causally affect the host physiology2021
- Author(s)
  本田賢也
- Organizer
  KEYSTONE SYMPOSIA
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05627
[Presentation] 腸内細菌による抗生物質耐性菌・ウィルス感染制御2021
- Author(s)
  本田賢也
- Organizer
  第70回日本感染症学会東日本地方会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H05627
[Presentation] 腸内細菌と発がん2021
- Author(s)
  本田賢也
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20H05627
[Presentation] Mining the gut microbiota and identifying effector microbes that causally affect the host physiology2021
- Author(s)
  本田賢也
- Organizer
  第5回日本循環器学会基礎研究フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-20H05627
[Presentation] 腸内細菌を標的とする疾患治療2021
- Author(s)
  本田賢也
- Organizer
  第34回日本外科感染症学会総会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H05627
[Presentation] 免疫とマイクロバイオーム2021
- Author(s)
  本田賢也
- Organizer
  第42回日本炎症・再生医学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H05627
[Presentation] 腸内細菌を標的とした疾患治療法の開発2021
- Author(s)
  本田賢也
- Organizer
  第109回日本泌尿器科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20H05627
[Presentation] SFB-mediated TH17 cell induction is influenced by mouse genetic background.2015
- Author(s)
  Tanoue T, Atarashi K, Nagano U, Watanabe E, Narushima S, Umesaki Y, Honda K.
- Organizer
  第44回日本免疫学会総会
- Place of Presentation
  札幌コンベンションセンター・札幌・北海道
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-26670194
[Presentation] Induction of intestinal Th1 cells by human salivary microbiota.2015
- Author(s)
  Atarashi K, Narushima S, Tanoue T, Nagano U, Honda K.
- Organizer
  第44回日本免疫学会総会
- Place of Presentation
  札幌コンベンションセンター・札幌・北海道
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-26670194
[Presentation] Commensal Bacteria-Mediated Treg Induction2011
- Author(s)
  Kenya Honda
- Organizer
  Keystone Symposium Dendritic Cells and the Initiation of Adaptive Immunity
- Place of Presentation
  Santa Fe, USA
- Year and Date
  2011-02-15
- Data Source
  KAKENHI-PROJECT-21390150
[Presentation] Immune regulation by intestinal microflora2010
- Author(s)
  Kenya Honda
- Organizer
  Surface Barrier Immunology Study Group(SBARIS)2nd meting
- Place of Presentation
  第一ホテル両国(東京都・墨田区)
- Year and Date
  2010-01-29
- Data Source
  KAKENHI-PROJECT-21390150
[Presentation] Regulation of adaptive immune cell differentiation by intestinal commensal bacteria2010
- Author(s)
  本田賢也
- Organizer
  2nd TNO Beneficial Microbes Conference
- Place of Presentation
  NH Conference Centre Leeuwenhorst in Noordwijkerhout(オランダ)
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-20057013
[Presentation] Immune regulation by intestinal microflora2010
- Author(s)
  本田賢也
- Organizer
  Surface Barrier Immunology Study Group(SBARIS)2nd meting
- Place of Presentation
  第一ホテル両国(東京都・墨田区)
- Year and Date
  2010-01-29
- Data Source
  KAKENHI-PROJECT-20057013
[Presentation] Regulation of adaptive immune cell differentiation by intestinal commensal bacteria2010
- Author(s)
  Kenya Honda
- Organizer
  2nd TNO Beneficial Microbes Conference
- Place of Presentation
  NH Conference Centre Leeuwenhorst in Noordwijkerhout(オランダ)
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-21390150
[Presentation] 腸内細菌によるTh17細胞の分化誘導機構2009
- Author(s)
  本田賢也
- Organizer
  日本インターフェロン・サイトカイン学会学術集会
- Place of Presentation
  京都大学医学部芝蘭会館(京都府)
- Year and Date
  2009-06-26
- Data Source
  KAKENHI-PROJECT-21390150
[Presentation] 腸内フローラによる免疫系制御2009
- Author(s)
  本田賢也
- Organizer
  高遠シンポジウム
- Place of Presentation
  高遠さくらホテル(長野県伊那市高遠町)
- Year and Date
  2009-08-28
- Data Source
  KAKENHI-PROJECT-21390150
[Presentation] Immune regulation by intestinal microflora2009
- Author(s)
  本田賢也
- Organizer
  日本免疫学会総会・学術集会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-20057013
[Presentation] 腸内フローラによるTH17 細胞誘導2009
- Author(s)
  本田賢也、新幸二、竹田潔
- Organizer
  第82回日本細菌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-19390137
[Presentation] Immune regulation by intestinal microflora2009
- Author(s)
  本田賢也
- Organizer
  The 9th Awaji International Forum on Infection and Immunity(AIFII)
- Place of Presentation
  The Westin Awaji Island Hotel(兵庫県)
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-20057013
[Presentation] Mechanism of Th17 cell differentiation in the intestinal lamina propria2009
- Author(s)
  Kenya Honda
- Organizer
  The 9th World Congress of Inflammation
- Place of Presentation
  京王プラザホテル(東京都)
- Year and Date
  2009-07-09
- Data Source
  KAKENHI-PROJECT-21390150
[Presentation] Immune regulation by intestinal microflora2009
- Author(s)
  本田賢也
- Organizer
  日本免疫学会総会・学術集会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-21390150
[Presentation] 腸内細菌によるTh17細胞の分化誘導機構2009
- Author(s)
  本田賢也
- Organizer
  日本インターフェロン・サイトカイン学会学術集会
- Place of Presentation
  京都大学医学部芝蘭会館(京都府)
- Year and Date
  2009-06-26
- Data Source
  KAKENHI-PROJECT-20057013
[Presentation] 腸内フローラによる免疫系制御2009
- Author(s)
  本田賢也
- Organizer
  高遠シンポジウム
- Place of Presentation
  高遠さくらホテル(長野県伊那市高遠町)
- Year and Date
  2009-08-28
- Data Source
  KAKENHI-PROJECT-20057013
[Presentation] Regulation of adaptive immune cell differentiation by intestinal commensal bacteria2009
- Author(s)
  本田賢也
- Organizer
  US-Japan GI Executive Meeting
- Place of Presentation
  京都府
- Year and Date
  2009-06-19
- Data Source
  KAKENHI-PROJECT-20057013
[Presentation] Regulation of adaptive immune cell differentiation by intestinal commensal bacteria2009
- Author(s)
  Kenya Honda
- Organizer
  US-Japan GI Executive Meeting
- Place of Presentation
  京都府
- Year and Date
  2009-06-19
- Data Source
  KAKENHI-PROJECT-21390150
[Presentation] Mechanism of Th17 cell differentiation in the intestinal lamina propria2009
- Author(s)
  本田賢也
- Organizer
  The 9th World Congress of Inflammation
- Place of Presentation
  京王プラザホテル(東京都)
- Year and Date
  2009-07-09
- Data Source
  KAKENHI-PROJECT-20057013
[Presentation] Immune regulation by intestinal microflora2009
- Author(s)
  Kenya Honda
- Organizer
  The 9th Awaji International Forum on Infection and Immunity(AIFII)
- Place of Presentation
  The Westin Awaji Island Hotel(兵庫県)
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-21390150
[Presentation] Extracellular ATP from commensal bacteria drives lamina propria TH17 cell differentiation2008
- Author(s)
  Kenya Honda, Koji Atarashi, Junichi Nishimura, and Kiyoshi Takeda
- Organizer
  Cold Spring Harbor Laboratory Meeting
- Place of Presentation
  New York
- Data Source
  KAKENHI-PROJECT-19390137
[Presentation] Extracellular ATP activates intestinal lamina propria dendritic cells to induce TH17 cells2008
- Author(s)
  Kenya Honda
- Organizer
  第10回国際樹状細胞シンポジウム
- Place of Presentation
  神戸
- Year and Date
  2008-10-03
- Data Source
  KAKENHI-PROJECT-19390137
[Presentation] Commensal bacteria-derived ATP drives lamina propria TH17 cells2008
- Author(s)
  Kenya, Honda
- Organizer
  Colloquium for the study of gastrointestinal defense system
- Place of Presentation
  Kitano Hospital, Osaka
- Year and Date
  2008-01-12
- Data Source
  KAKENHI-PROJECT-18060008
[Presentation] Extracellular ATP drives lamina propria TH17 cell differentiation2008
- Author(s)
  本田賢也
- Organizer
  日本分子生物学会第32回年会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20057013
[Presentation] Commensal bacteria-derived ATP drives lamina propria TH17 cells2008
- Author(s)
  Kenya Honda
- Organizer
  Colloquium for the study of gastrointestinal defense system
- Place of Presentation
  Kitano Hospital, Osaka
- Year and Date
  2008-01-12
- Data Source
  KAKENHI-PROJECT-19390137
[Presentation] Extracellular ATP activates intestinal lamina propr iadendri tic cells to induce TH17 cells2008
- Author(s)
  Kenya Honda
- Organizer
  第10回国際樹状細胞シンポジウム
- Place of Presentation
  神戸
- Year and Date
  2008-10-03
- Data Source
  KAKENHI-PROJECT-19390137
[Presentation] Extracellular ATP from commensal bacteria drives lamina propria TH17 cell differentiation2008
- Author(s)
  Kenya Honda, Koji Atarashi, Junichi Nishimura, and Kiyoshi Takeda
- Organizer
  JSI-RCAI Workshop 2008 粘膜免疫機構の制御と破綻
- Place of Presentation
  横浜
- Year and Date
  2008-03-14
- Data Source
  KAKENHI-PROJECT-19390137
[Presentation] Extracellular ATP drives lamina propria TH17 cell differentiation2008
- Author(s)
  Kenya Honda, Koji Atarashi, Junichi Nishimura, Kiyoshi Takeda
- Organizer
  BMB2008
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19390137

1. TAKAOKA Akinori (30323611)

# of Collaborated Projects: 6 results

# of Collaborated Products: 35 results
2. OOBA Yuusuke (30333503)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
3. TANIGUCHI Tadatsugu (50133616)

# of Collaborated Projects: 2 results

# of Collaborated Products: 27 results
4. YANAI Hideyuki (70431765)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
5. Narushima Seiko (80578336)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. TAMURA Tonohiko (50285144)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. TAKEDA Kiyoshi (20309446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
8. TAYA Chouji (90175456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. OGURA Yoshio (00135849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ATARASHI Koji (60546787)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. Akazawa Hiroshi (20396683)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KOMURO Issei (30260483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KAMO Takehiro (10722556)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. MORITA Hidetoshi (70257294)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. HATTORI Masahira (70175537)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Nishikawa Hiroyoshi (10444431)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. DOKI Yuichiro (20291445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 高柳広 (20334229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 田中信之 (80222115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 寺嶋秀騎 (60912897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. Li Youxian (20840185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
22. KEARNEY SEAN

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. 後藤義幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 畠山昌則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HONDA Kenya 本田 賢也

本田 賢也 ホンダ ケンヤ

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Co-Researchers

Unraveling the principles of microbiota function for rationally-designed biotherapeuticsPrincipal Investigator

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常在菌Akkermansiaと恒常的宿主免疫応答を決定する細菌ゲノム因子の同定Principal Investigator

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消化管免疫系の状態を決定する腸内細菌の探索Principal Investigator

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樹状細胞主導の消化管粘膜バリアー維持機構Principal Investigator

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Regulatory signaling in intestinal dendritic cells preventing inflammatory bowel diseasesPrincipal Investigator

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インターフェロン制御因子ファミリー活性化の時空間ダイナミクスの解析Principal Investigator

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自然免疫系と獲得免疫系の連携における細胞特異的IFN遺伝子発現ネットワークの解析Principal Investigator

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HONDA Kenya 本田賢也

本田賢也ホンダケンヤ