KIMURA Tadashi 木村忠史

Researcher Number	60344214
Other IDs
Affiliation (based on the past Project Information) *help	2018 – 2020: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員 2015: 国立研究開発法人産業技術総合研究所, 創薬基盤研究部門, 主任研究員 2014: 独立行政法人産業技術総合研究所, 糖鎖創薬技術研究センター, 主任研究員 2010 – 2013: 独立行政法人産業技術総合研究所, バイオメディカル研究部門, 主任研究員
Review Section/Research Field	Principal Investigator Chemical biology / ケミカルバイオロジー Except Principal Investigator Anesthesiology / Basic Section 55050:Anesthesiology-related
Keywords	Principal Investigator パドルキメラ / パッチクランプ / 進化分子工学 / 電位センサー / イオンチャネル / ICK / 大腸菌 / 電気生理 / PERISS法 / カルシウムチャネル … More / ペプチド / トランスクリプトーム / cDNAライブラリー / スキャフォールド / 次世代シーケンス / 毒液 / トランスクリプトーム解析 / 生理活性ペプチド / 毒腺 / タランチュラ … More Except Principal Investigator ナトリウムチャネル / 新規鎮痛薬 / Nav1.7阻害薬 / ミスセンス / Nav1.7 / ウインドウカレント / パッチクランプ / ノックインマウス / 変異 / ramp電流 / 遺伝子変異 / バイオインフォマティクス / 創薬 / 1塩基変異 / ナトリウムチャネル1.7 / 無痛症 / 局所麻酔薬 / 痛み Less

Development of novel Nav1.7 antagonist by using molecular pharmacological methods
- Principal Investigator
  
  Ishida Takashi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Shinshu University
Discovery of novel Nav1.7 inhibitors by using bioinformatics
- Principal Investigator
  
  Kawamata Mikito
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Anesthesiology
- Research Institution
  Shinshu University
Peptide drug discovery to identify the calcium channel subfamily by molecular evolutional techniquePrincipal Investigator
- Principal Investigator
  
  Kimura Tadashi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical biology
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Search and analysis of bioactive peptides from a spider venom glandPrincipal Investigator
- Principal Investigator
  
  KIMURA Tadashi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  ケミカルバイオロジー
- Research Institution
  National Institute of Advanced Industrial Science and Technology

All 2016 2015 2014 2012

All Journal Article Presentation

[Journal Article] In vivo support for the new concept of pulmonary blood flow-mediated CO2 gas excretion in the lungs2015
- Author(s)
  Kawai Y, Ajima K, Kaidoh M, Sakaguchi M, Tanaka S, Kawamata M, Kimura H, and Ohhashi T
- Journal Title
  
  Am J Physiol Lung Mol
  
  Volume: in press Issue: 12 Pages: 263-8
- DOI
  10.1152/ajplung.00205.2014
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590272, KAKENHI-PROJECT-26350145, KAKENHI-PROJECT-15K15568, KAKENHI-PROJECT-15H02562, KAKENHI-PROJECT-24390365
[Journal Article] The application of the Escherichia coli giant spheroplast for drug screening with automated planar patch clamp system2015
- Author(s)
  Kyoko Kikuchi, Mika Sugiura, Chizuko Nishizawa-Harada and Tadashi Kimura
- Journal Title
  
  Biotechnology Reports
  
  Volume: 7 Pages: 17-23
- DOI
  10.1016/j.btre.2015.04.007
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25350984
[Journal Article] High proteolytic resistance of spider-derived inhibitor cystine knots2015
- Author(s)
  Kyoko Kikuchi, Mika Sugiura and Tadashi Kimura
- Journal Title
  
  International Journal of Peptides
  
  Volume: 2015 Pages: 537508-537508
- DOI
  10.1155/2015/537508
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25350984
[Journal Article] 標的分子とタンパク質ライブラリーの今日発現系によるペプチド創製2014
- Author(s)
  木村忠史
- Journal Title
  
  化学工業
  
  Volume: Vol.65, No1265 Pages: 19-25
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25350984
[Journal Article] Molecular Cloning and Sequence Analysis of the cDNAs Encoding Toxin-Like Peptides from the Venom Glands of Tarantula Grammostola rosea2012
- Author(s)
  Tadashi Kimura, Seigo Ono and Tai Kubo
- Journal Title
  
  International journal of peptides
  
  Volume: Vol. 2012 Pages: 731293-731293
- DOI
  10.1155/2012/731293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22603016
[Presentation] ICK peptides, their proteolysis-resistance2016
- Author(s)
  Tadashi Kimura
- Organizer
  AsiaTIDES2016
- Place of Presentation
  京都
- Year and Date
  2016-02-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25350984
[Presentation] ICKペプチドのプロテアーゼ耐性の検討2016
- Author(s)
  木村忠史
- Organizer
  日本薬学会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25350984

1. KUBO Tai (10178030)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. Ishida Takashi (60531952)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Kameyama Kimihiko (50224697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Kawamata Mikito (90315523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Ueda Hiroshi (00145674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 清澤研吉 (50624772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 中田勉 (70452141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 山田充彦 (10263237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 上園保仁 (20213340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 杉山由紀 (10468100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. AJIMA Kumiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 河合佳子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 大橋俊夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KIMURA Tadashi 木村 忠史

Research Projects

Research Products

Co-Researchers

Development of novel Nav1.7 antagonist by using molecular pharmacological methods

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Discovery of novel Nav1.7 inhibitors by using bioinformatics

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Peptide drug discovery to identify the calcium channel subfamily by molecular evolutional techniquePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Search and analysis of bioactive peptides from a spider venom glandPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] In vivo support for the new concept of pulmonary blood flow-mediated CO2 gas excretion in the lungs2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The application of the Escherichia coli giant spheroplast for drug screening with automated planar patch clamp system2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High proteolytic resistance of spider-derived inhibitor cystine knots2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 標的分子とタンパク質ライブラリーの今日発現系によるペプチド創製2014

Author(s)

Journal Title

Data Source

[Journal Article] Molecular Cloning and Sequence Analysis of the cDNAs Encoding Toxin-Like Peptides from the Venom Glands of Tarantula Grammostola rosea2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] ICK peptides, their proteolysis-resistance2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ICKペプチドのプロテアーゼ耐性の検討2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

KIMURA Tadashi 木村忠史