MAMIYA Kazuhisa 間宮和久

Researcher Number	60344610
External Links
Affiliation (based on the past Project Information) *help	2007: Shinshu University, 医学部, 助教 2003 – 2006: 弘前大学, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Ophthalmology Except Principal Investigator Ophthalmology / Ophthalmology
Keywords	Principal Investigator ソノポレーション / 神経保護効果 / グアニレートシクラーゼ / エレクトロポレーション / 遺伝子導入 / 緑内障濾過手術 / 緑内障手術 / エレクトロポレーション法 / matrix metalloproteinase-3 Except Principal Investigator アポトーシス … More / カルシウム拮抗剤 / 網膜電図 / ロドプシン / 視細胞 / 網膜変性 / 網膜色素変性 / TIMP / MMP / NMDA / 網膜神経節細胞 / アントシアニン / モデル動物 / レチノイド / 網膜変性症 / 動物モデル / 燐酸化 / 薬物治療 / 神経保護 / 緑内障 / extracellular matrix / α-adrenergic receptor / ocular surface / neuroprotection / antiglaucoma eye drops / tissue inhibitor of metalloprotease / matrix metalloprotease / 濾過手術 / 眼圧下降作用 / glial fibrillary acidic protein / N-methyl-D-asartate / 細胞外マトリクス / α受容体 / 眼表面組織 / 神経保護効果 / 抗緑内障点眼薬 / retinitis pigmentosa / anthocyanin / retinoid / electroretinogram / calcium channel blocker / photoreceptor cell / rhodopsin / retinal degeneration / Ca2+拮抗剤 / DNA microarray / 癌関連網膜症 / ロドプシンキナーゼ / calcium antagonist / neuron specific enolase(NSE) / apoptosis / autoantibody / retinal ganglion cell / autoimmunity / optic nerve / glaucoma / ニューロン特異エノラーゼ / 神経特異エノラーゼ(NSE) / 自己抗体 / 自己免疫 / 視神経 / ロジプシン / 分子病態 / リン酸化 / カルシウムチャンネルブロッカー / カルシウム / 視興奮 / 網膜色素上皮 / 修飾因子 / 網膜光傷害 / GCAP2 / rdsマウス / カルシウム拮抗薬 / カルシウム結合タンパク質 / electroporation法 / 遺伝子治療 / nipradilol / NO作用 / 抗緑内障薬 / エレクトロポレーション / グアニル酸シクラーゼ Less

Identification of molecular pathology of retinal degeneration
- Principal Investigator
  
  OHGURO Hiroshi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Sapporo Medical University
視神経乳頭周囲への遺伝子導入Principal Investigator
- Principal Investigator
  
  間宮和久
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Shinshu University
  Hirosaki University
新規の網膜細胞障害判定システムの確立:網膜変性に対する新しい治療法確立を目指して
- Principal Investigator
  
  大黒浩
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  Sapporo Medical University
  Hirosaki University
網膜変性症の修飾因子としての視細胞特異的カルシウム結合タンパクの役割
- Principal Investigator
  
  中澤満
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  Hirosaki University
エレクトロポレーション法による局所遺伝子導入法を用いた新しい緑内障濾過手術の開発Principal Investigator
- Principal Investigator
  
  間宮和久
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Hirosaki University
Study of effects of antiglaucoma eye drops on glaucomatous optic neuropathy and ocular serface.
- Principal Investigator
  
  OHGURO Ikuyo
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Hirosaki University
遺伝子導入による新しい薬剤効果増強法を用いた緑内障に対する神経保護治療の開発(抗緑内障薬nipradilolの持つNO作用の増強を目指して)
- Principal Investigator
  
  OHGURO Hiroshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  Hirosaki University
New drug therapy for retinal degeneration using calcium channel blockers
- Principal Investigator
  
  OHGURO Hiroshi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Hirosaki University
Study of autoimmune mechanisms in molecular pathology of glaucomatous optic neuropathy.
- Principal Investigator
  
  OHGURO Ikuyo
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Hirosaki University

All 2006 2005 2004 2003

All Journal Article Book

[Book] ハンドピース・チップの再使用、「術後眼内炎」(分担執筆)2005
- Author(s)
  間宮和久, 中澤満
- Total Pages
  280
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-16791039
[Book] ハンドピース・チップの再使用、「術後眼内炎」分担執筆2005
- Author(s)
  間宮和久, 中澤満
- Total Pages
  280
- Publisher
  文光堂, 東京
- Data Source
  KAKENHI-PROJECT-16659471
[Journal Article] Effects of anti-glaucoma drops on matrix metalloproteinase (MMP) and tissue inhibitor metalloproteinase (TIMP) balance in conjunctival and subconjunctival tissue.2006
- Author(s)
  Ito T, Ohguro H, Ohguro I, Mamiya K, Nakazawa M.
- Journal Title
  
  Invest Ophthalmol Vis Sci 47
  
  Pages: 823-830
- Data Source
  KAKENHI-PROJECT-18390463
[Journal Article] Effects of Antiglaucoma Drops on MMP and TIMP Balance in Conjunctival and Subconjunctival Tissue.2006
- Author(s)
  Ito T, Mamiya K et al.
- Journal Title
  
  Invest Ophthalmol Vis Sci. 47(3)
  
  Pages: 823-830
- Data Source
  KAKENHI-PROJECT-16791039
[Journal Article] Effects of anti-glaucoma drops on matrix metalloproteinase (MMP) and tissue inhibitor metalloproteinase (TIMP) balance in conjunctival and subconjunctival tissue2006
- Author(s)
  Ito T, Ohguro H, Ohguro I, Mamiya K, Nakazawa M.
- Journal Title
  
  Invest Ophthalmol Vis Sci 47
  
  Pages: 823-830
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390463
[Journal Article] Effects of anti-glaucoma drops on matrix metalloproteinase (MMP) and tissue inhibitor metalloproteinase (TIMP) balance in conjunctival and subconjunctival tissue.2006
- Author(s)
  Ito T, Ohguro H, Ohguro I, Mamiya K, Nakazawa M
- Journal Title
  
  Invest Ophthalmol Vis Sci 47
  
  Pages: 823-830
- Data Source
  KAKENHI-PROJECT-17659540
[Journal Article] Prolonged rhodopsin phosphorylation in light-induced retinal degeneration in rat models.2006
- Author(s)
  Ishikawa F, Ohguro H, Ohguro I, Yamazaki H, Mamiya K, Metoki T, Ito T, Yokoi Y, Nakazawa M.
- Journal Title
  
  Invest Ophthalmol Vis Sci 47
  
  Pages: 5204-5211
- Data Source
  KAKENHI-PROJECT-18390463
[Journal Article] Effects of Antiglaucoma Drops on MMP and TIMP Balance in Conjunctival and Subconjunctival Tissue.2006
- Author(s)
  Ito T, Mamiya K, et al.
- Journal Title
  
  Invest.Ophthalmol.Vis.Sci. 47・3
  
  Pages: 823-830
- Data Source
  KAKENHI-PROJECT-18791255
[Journal Article] Prolonged Rhodopsin Phosphorylation in Light-Induced Retinal Degeneration in Rat Models2006
- Author(s)
  Ishikawa F, Mamiya K, et al.
- Journal Title
  
  Invest.Ophthalmol.Vis.Sci. 47・12
  
  Pages: 5204-5211
- Data Source
  KAKENHI-PROJECT-18791255
[Journal Article] Effects of anti-glaucoma drops on MMP and TIMP balance in conjunctival and subconjunctival tissue.2006
- Author(s)
  Ito I, Ohguro H, Ohgro I, Mamiya K, Nakazawa M.
- Journal Title
  
  Invest Ophthalmol Vis Sci 47(3)
  
  Pages: 823-830
- Data Source
  KAKENHI-PROJECT-16659471
[Journal Article] Prolonged rhodopsin phosphorylation in light-induced retinal degeneration in rat models2006
- Author(s)
  Ishikawa F, Ohguro H, Ohguro I, Yamazaki H, Mamiya K, Metoki T, Ito T, Yokoi Y, Nakazawa M.
- Journal Title
  
  Invest Ophthalmol Vis Sci 47
  
  Pages: 5204-5211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390463
[Journal Article] Prolonged rhodopsin phosphorylation in light-induced retinal degeneration in rat models.2006
- Author(s)
  Ishikawa F, Ohguro H, Ohguro I, Yamazaki H, Mamiya K, Metoki T, Ito T, Yokoi Y, Nakazawa M
- Journal Title
  
  Invest Ophthalmol Vis Sci 47
  
  Pages: 5204-5211
- Data Source
  KAKENHI-PROJECT-17659540
[Journal Article] Effects of anti-glaucoma drops on NMDA-induced retinal dysfunctions.2005
- Author(s)
  Metoki T, Ohguro H, Ohguro I, Mamiya K, Ito T, Nakazawa M.
- Journal Title
  
  Jpn J Ophthalmol 49
  
  Pages: 453-461
- Data Source
  KAKENHI-PROJECT-17659540
[Journal Article] Study of effects of antiglaucoma eye drops on N-methyl-D-aspartate-induced retinal damage.2005
- Author(s)
  Metoki T, Mamiya K et al.
- Journal Title
  
  Jpn J Ophthalmol. 49(6)
  
  Pages: 453-461
- NAID
  10019218837
- Data Source
  KAKENHI-PROJECT-16791039
[Journal Article] 中心窩脈絡膜新生血管に対するlimited macular translocationの手術成績2005
- Author(s)
  山崎仁志, 間宮和久, 他
- Journal Title
  
  臨床眼科 59(1)
  
  Pages: 71-75
- Data Source
  KAKENHI-PROJECT-16791039
[Journal Article] 中心窩下脈絡膜新生血管に対するlimited macular translocationの手術成績2005
- Author(s)
  山崎仁志, 間宮和久ら
- Journal Title
  
  臨床眼科 59(1)
  
  Pages: 71-75
- Data Source
  KAKENHI-PROJECT-16791039
[Journal Article] Effects of anti-glaucoma drops on NMDA-induced retinal dysfunctions.2005
- Author(s)
  Metoki T, Ohguro H, Ohguro I, Mamiya K, Ito T, Nakazawa M.
- Journal Title
  
  Jpn J Ophthalmol 49
  
  Pages: 453-461
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390523
[Journal Article] 25Gシステムによる硝子体切除術に白内障および緑内障濾過手術を同時に施行し,良好な経過をたどった緑内障合併黄斑偽円孔の1症例.2005
- Author(s)
  大黒浩, 間宮和久ら
- Journal Title
  
  眼科 47(8)
  
  Pages: 1131-1135
- Data Source
  KAKENHI-PROJECT-16791039
[Journal Article] Effects of matrix metalloproteinase-3 gene transfer by electroporation in glaucoma filter surgery.2004
- Author(s)
  Mamiya K, Ohguro I et al.
- Journal Title
  
  Exp Eye Res 79
  
  Pages: 405-410
- Data Source
  KAKENHI-PROJECT-16591738
[Journal Article] Clinical and immunologic aspects of cancer-associated retinopathy2004
- Author(s)
  Ohguro H, Mamiya K et al.
- Journal Title
  
  Am.J.Ophthalmol. 137(6)
  
  Pages: 117-119
- Data Source
  KAKENHI-PROJECT-16791039
[Journal Article] マウス角膜線維芽細胞由来の不死化培養細胞における培養下コラーゲン線維形成におけるlumicanの効果2004
- Author(s)
  間宮和久, 中澤満
- Journal Title
  
  弘前医学 55(3,4)
  
  Pages: 108-114
- NAID
  110004772524
- Data Source
  KAKENHI-PROJECT-16791039
[Journal Article] Study of effects of calcium channel blockers on retinal degeneration of rd mouse.2004
- Author(s)
  Takano Y, Ohguro H, Dezawa M, Ishikawa H, Yamazaki H, Ohguro I, Mamiya K, Metoki T, Ishikawa F, Nakazawa M.
- Journal Title
  
  Biochem Biophys Res Commun 313
  
  Pages: 1015-1022
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390523
[Journal Article] Effects of matrix metalloproteinase-3 gene transfer by electroporation in glaucoma surgery2004
- Author(s)
  Mamiya K, et al.
- Journal Title
  
  EXPERIMENTAL EYE RESEARCH 79(7)
  
  Pages: 405-410
- Data Source
  KAKENHI-PROJECT-16791039
[Journal Article] Effects of MMC III gene transfer by electroporation in glaucoma filter surgery.2004
- Author(s)
  Mamiya K, Ohguro H, Nakazawa M.他
- Journal Title
  
  Experimental Eye Research 79(7)
  
  Pages: 405-410
- Data Source
  KAKENHI-PROJECT-16659471
[Journal Article] Effects of matrix metalloprotease-3 gene transfer by electroporation in glaucoma surgery.2004
- Author(s)
  Mamiya K, Ohguro I, et al.
- Journal Title
  
  Exp Eye Res 79
  
  Pages: 405-410
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591738
[Journal Article] Free-flapによる毛様体扁平部濾過手術併用硝子体手術を施行した血管新生緑内障の3例2004
- Author(s)
  大黒浩, 間宮和久, 他
- Journal Title
  
  あたらしい眼科 21(12)
  
  Pages: 1697-1699
- Data Source
  KAKENHI-PROJECT-16791039
[Journal Article] Study of drug effects of calcium channel blockers on retinal degeneration of rd mouse2004
- Author(s)
  Takano Y, Mamiya K et al.
- Journal Title
  
  Biochem.Biophys.Res.Com. 313
  
  Pages: 1015-1022
- Data Source
  KAKENHI-PROJECT-16791039
[Journal Article] Effects of matrix metalloproteinase-3 gene transfer by electroporation in glaucoma2004
- Author(s)
  Mamiya K, Ohguro H et al.
- Journal Title
  
  Exp.Eye Res. 79
  
  Pages: 405-410
- Data Source
  KAKENHI-PROJECT-15659408
[Journal Article] Effects of matrix metalloproteinase-3 gene transfer by electroporation in glaucoma surgery.2004
- Author(s)
  Mamiya K, Ohguro H, Ohguro I, Metoki T, Ishikawa F, Yamazaki H, Takano Y, Ito T, Nakazawa M.
- Journal Title
  
  Exp.Eye Res 79
  
  Pages: 405-410
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390523
[Journal Article] Effects of matrix metalloproteinase-3 gene transfer by electroporation in glaucoma2004
- Author(s)
  Mamiya K, Ohguro H et al.
- Journal Title
  
  Exp.Eye Res. 79
  
  Pages: 405-410
- Data Source
  KAKENHI-PROJECT-15390523
[Journal Article] Effects of matrix metalloproteinase-3 gene transfer by electroporation in glaucoma filter surgery.2004
- Author(s)
  Mamiya K, Ohguro I, et al.
- Journal Title
  
  Exp Eye Res 79
  
  Pages: 405-410
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591738
[Journal Article] Study of pharmacological effects of nilvadipine on RCS rat retinal degeneration by microarray analysis.2003
- Author(s)
  Sato M, Ohguro H, Ohguro I, Mamiya K, Takano Y, Yamazaki H, Metoki T, Miyagawa Y, Ishikawa F, Nakazawa M.
- Journal Title
  
  Biochem Biophys Res Commun 306
  
  Pages: 826-831
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390523
[Journal Article] Prolonged survival of the phosphorylated form of rhodopsin during dark adaptation of royal college surgeons rat.2003
- Author(s)
  Ohguro H, Ohguro I, Mamiya K, Maeda T, Nakazawa M.
- Journal Title
  
  FEBS letters 551
  
  Pages: 128-132
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390523
[Journal Article] Low expression of rhodopsin kinase in pineal gland in Royal College Surgeons rat.2003
- Author(s)
  Takano Y, Ohguro H, Ohguro I, Yamazaki H, Mamiya K, Ishikawa F, Nakazawa M.
- Journal Title
  
  Curr Eye Res 27
  
  Pages: 95-102
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390523

1. NAKAZAWA Mitsuru (80180272)

# of Collaborated Projects: 7 results

# of Collaborated Products: 16 results
2. OHGURO Hiroshi (30203748)

# of Collaborated Projects: 7 results

# of Collaborated Products: 20 results
3. OHGURO Ikuyo (90305235)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
4. 山崎仁志 (00374835)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
5. 三田村佳典 (30287536)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. ISHIKAWA Futoshi (00419962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. NISHIKIORI Nami (30444920)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KAWATA Hirokatsu (60438009)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 丸山幾代

# of Collaborated Projects: 0 results

# of Collaborated Products: 18 results

MAMIYA Kazuhisa 間宮 和久

Research Projects

Research Products

Co-Researchers

Identification of molecular pathology of retinal degeneration

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

視神経乳頭周囲への遺伝子導入Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新規の網膜細胞障害判定システムの確立:網膜変性に対する新しい治療法確立を目指して

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

網膜変性症の修飾因子としての視細胞特異的カルシウム結合タンパクの役割

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

エレクトロポレーション法による局所遺伝子導入法を用いた新しい緑内障濾過手術の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of effects of antiglaucoma eye drops on glaucomatous optic neuropathy and ocular serface.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

遺伝子導入による新しい薬剤効果増強法を用いた緑内障に対する神経保護治療の開発(抗緑内障薬nipradilolの持つNO作用の増強を目指して)

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New drug therapy for retinal degeneration using calcium channel blockers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of autoimmune mechanisms in molecular pathology of glaucomatous optic neuropathy.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] ハンドピース・チップの再使用、「術後眼内炎」(分担執筆)2005

Author(s)

Total Pages

Publisher

Data Source

[Book] ハンドピース・チップの再使用、「術後眼内炎」分担執筆2005

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Effects of anti-glaucoma drops on matrix metalloproteinase (MMP) and tissue inhibitor metalloproteinase (TIMP) balance in conjunctival and subconjunctival tissue.2006

Author(s)

Journal Title

Data Source

[Journal Article] Effects of Antiglaucoma Drops on MMP and TIMP Balance in Conjunctival and Subconjunctival Tissue.2006

Author(s)

Journal Title

Data Source

[Journal Article] Effects of anti-glaucoma drops on matrix metalloproteinase (MMP) and tissue inhibitor metalloproteinase (TIMP) balance in conjunctival and subconjunctival tissue2006

Author(s)

Journal Title

Data Source

MAMIYA Kazuhisa 間宮和久