Araki Yasuhiro 荒木保弘

… Alternative Names

Researcher Number	60345254
Other IDs
External Links
Affiliation (Current)	2022: 大阪大学, 大学院歯学研究科, 助教
Affiliation (based on the past Project Information) *help	2018 – 2021: 大阪大学, 歯学研究科, 助教 2011 – 2015: 東京工業大学, フロンティア研究機構, 特任助教 2012: 東京工業大学, フロンティア研究機構, 助教 2002 – 2004: The University of Tokyo, Graduate School of Pharmaceutical Sciences, Dept. of Physiol. Chem., Research Associate, 大学院・薬学系研究科, 助手
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological Sciences / Molecular biology / Basic Section 43030:Functional biochemistry-related / Basic Section 44010:Cell biology-related Except Principal Investigator Biological Sciences / Functional biochemistry / Biological pharmacy / Biological pharmacy / Functional biochemistry
Keywords	Principal Investigator 酵母 / G蛋白質 / mRNA分解 / NMD経路 / Ski7 / Upf因子群 / Ski複合体 / エキソソーム / オートファジー / リン酸化 … More Except Principal Investigator JNK / MAPキナーゼ / G蛋白質 / 翻訳終結 / mRNA動態 / アポトーシス / SEK1 / リボソーム / ポリA結合蛋白質 / 脱アデニル化 / ストレス / mRNA分解 / NMD経路 / 翻訳終結因子 / エキソヌクレアーゼ / リン酸化酵素 / ATPアナログ / p38 / ポリA鎖結合蛋白質 / ポリA鎖分解 / ノックアウトマウス / シグナル伝達 / 染色体分離 / G protein / signal transduction / c-Jun / NFκB / MAP kinase / 翻訳 / 翻訳開始 / translation termination / mRNA / apoptosis / SAPK / マスト細胞 / ES細胞 / MKK7 / IgE受容体 / 顆粒放出 / インターロイキン3 / 幹細胞増殖因子 / Ski7蛋白質 / UPF因子 / 紫外線 / mRNAデアデニレーゼ / ERK / Gab2 / 神経変性疾患 / 好中球 / PI3キナーゼ / 細胞老化 / 小胞輸送 / エンドサイトーシス / 受容体 / リン酸化 / 微小管 / PI3-キナーゼ / Rab5 / RIN / アンフィファイシンII / Rab / アンフィファイシン / Ras / イノシトールリン脂質3キナーゼ / 細胞膜受容体 / 3量体Gタンパク質 / チロシンキナーゼ / 核内輸送 / Small GTPase Rab5 / vesicle transport / endocytosis / receptor / phosphorylation / 胎児肝 / 肝芽細胞 / 造血幹細胞 / 骨髄細胞 / 幹細胞 / モノクローナル抗体 / アルブミン / fetal liver / hepatic bud / hematopoietic stem cells / ポリ(A)鎖 / ポリ(A)ヌクレアーゼ / 脱キャップ酵素 / 神経細胞死 / ポリA鎖短縮酵素 / Ski遺伝子産物 / Ski蛋白質 / mRNA degradation / poly(A) tail / poly(A) nuclease / GTP結合蛋白質 / poly (A) / poly (A)結合蛋白質 / mRNAデアデニレース / mRNAデアデニラーゼ / GTP-binding protein / translation / poly(A) / poly(A)-binding protein / mRNA deadenylase / 肝形成 / メダカ / 細胞死 / 内胚葉 / liver formation / knockout mice / Medaka / endoderm / stress Less

成長と増殖を司るTORC1のタンパク質分解システムを介した活性制御機構の解明Principal Investigator
- Principal Investigator
  
  荒木保弘
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Osaka University
細胞成長を司るTORC1の活性化を誘導するアミノ酸感知システムの包括的理解Principal Investigator
- Principal Investigator
  
  荒木保弘
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Osaka University
Elucidation of attenuation system for autophagy by phosphatasesPrincipal Investigator
- Principal Investigator
  
  Araki Yasuhiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Institute of Technology
Studies on regulation of autophagosome formation by kinases andphosphatasesPrincipal Investigator
- Principal Investigator
  
  ARAKI Yasuhiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Institute of Technology
ATPアナログ認識可能な変異MAPキナーゼを利用した標的リン酸化基質の探索
- Principal Investigator
  
  仁科博史
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
Analysis of Mutation Affecting Liver Development and Function in Mice and Medaka
- Principal Investigator
  
  NISHINA Hiroshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Medical and Dental University
  The University of Tokyo
がん原因遺伝子の検出法と治療への応用を目指したmRNA分解制御機構の解明Principal Investigator
- Principal Investigator
  
  荒木保弘
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
mRNAの翻訳と分解を制御する新規G蛋白質群の機能
- Principal Investigator
  
  星野真一
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
ATPアナログ認識可能な変異MAPキナーゼを利用したリン酸化基質の探索
- Principal Investigator
  
  仁科博史
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
遺伝子発現調節としてのmRNA分解:G蛋白質Ski7と脱キャップ酵素による制御Principal Investigator
- Principal Investigator
  
  荒木保弘
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  The University of Tokyo
翻訳とmRNA動態を制御する新規G蛋白質群の機能
- Principal Investigator
  
  星野真一
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
新規G蛋白質群を介したナンセンス変異をもつmRNAの分解経路の解析
- Principal Investigator
  
  堅田利明
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
ATPアナログ認識可能な変異MAPキナーゼを利用したリン酸化基質の探索
- Principal Investigator
  
  仁科博史
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo
Analysis of a novel G protein family involved in mRNA translation and decay
- Principal Investigator
  
  HOSHINO Shin-ichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo
Identification of hepatic stem cells and development of its separation methods : Analysis of the self-replication and survival of the cells
- Principal Investigator
  
  NISHINA Hiroshi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo
The structure and function of a novel G protein family regulating eukaryotic mRNA dynamics
- Principal Investigator
  
  KATADA Toshiaki
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo
G蛋白質共役型及びFc受容体を介したマスト細胞のシグナル伝達機構
- Principal Investigator
  
  NISHINA Hiroshi
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
G protein-dependent vectorial transportation of receptors, ion channels, and transporters
- Principal Investigator
  
  KATADA Toshiaki
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo

All 2021 2020 2019 2018 2013 2012 2011 2004 2003 2001 Other

All Journal Article Presentation

[Journal Article] Vacuolar protein Tag1 and Atg1-Atg13 regulate autophagy termination during persistent starvation in S. cerevisiae2021
- Author(s)
  Shintaro Kira , Masafumi Noguchi , Yasuhiro Araki , Yu Oikawa , Tamotsu Yoshimori , Aiko Miyahara , Takeshi Noda
- Journal Title
  
  Journal of Cell Science
  
  Volume: 134 Pages: 1-13
- DOI
  10.1242/jcs.253682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06111
[Journal Article] Starvation-induced autophagy via calcium-dependent TFEB dephosphorylation is suppressed by Shigyakusan2020
- Author(s)
  Ikari Sumiko、Lu Shiou-Ling、Hao Feike、Imai Kenta、Araki Yasuhiro、Yamamoto Yo-hei、Tsai Chao-Yuan、Nishiyama Yumi、Shitan Nobukazu、Yoshimori Tamotsu、Otomo Takanobu、Noda Takeshi
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Pages: 0230156-0230156
- DOI
  10.1371/journal.pone.0230156
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06111, KAKENHI-PROJECT-17H05088
[Journal Article] 栄養を感知して細胞成長を促すTORC1の制御機構2019
- Author(s)
  荒木保弘　野田健司
- Journal Title
  
  生産と技術
  
  Volume: 71 Pages: 77-80
- NAID
  40021969974
- Data Source
  KAKENHI-PROJECT-18K06111
[Journal Article] Gtr/Ego-independent TORC1 activation is achieved through a glutamine-sensitive interaction with Pib2 on the vacuolar membrane2018
- Author(s)
  Hirofumi Ukai, Yasuhiro Araki, Shintaro Kira, Yu Oikawa, Alexander I. May, Takeshi Noda
- Journal Title
  
  PLOS Genetics
  
  Volume: April Pages: 1-1
- DOI
  10.1016/j.dental.2018.07.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06111
[Journal Article] Atg38 is required for autophagy-specific phosphatidylinositol 3-kinase complex integrity.2013
- Author(s)
  Araki Y, Ku W-C, Akioka M, May AI, Hayashi Y, Arisaka F, Ishihama Y, Ohsumi Y.
- Journal Title
  
  Journal of Cell Biology
  
  Volume: 203(2) Pages: 299-313
- DOI
  10.1083/jcb.201304123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570190, KAKENHI-PUBLICLY-24116513, KAKENHI-PROJECT-24241062, KAKENHI-PROJECT-24659017, KAKENHI-PROJECT-25460063
[Journal Article] Awakening the hibernation of autophagy research using yeast2012
- Author(s)
  荒木保弘
- Journal Title
  
  Leading Author's
  
  Volume: e005 Pages: 1-10
- DOI
  10.7875/leading.author.1.e005
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-23890059
[Journal Article] オートファジーを長き眠りからめざめさせた酵母2012
- Author(s)
  荒木保弘、大隅良典
- Journal Title
  
  ライフサイエンス領域融合レビュー
  
  Volume: e005 Pages: 1-10
- Data Source
  KAKENHI-PROJECT-23890059
[Journal Article] The CENP-A chaperone Scm3 becomes enriched at kinetochores in anaphase independently of CENP-A incorporation.2011
- Author(s)
  Luconi L., Araki Y., Erlemann S. and Schiebel E
- Journal Title
  
  Cell Cycle
  
  Volume: 10 Pages: 3369-3378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890059
[Journal Article] A nobel small GTPase subfamily Gie capable of associating with tubulin is required for chromosome segregation.2004
- Author(s)
  T.Okai, Y.Araki, M.Tada, T.Tateno, K., T.Katada
- Journal Title
  
  Journal of Cell Science (印刷中)
- Data Source
  KAKENHI-PROJECT-15770106
[Journal Article] RIN3: a novel Rab5 GEF interacting with amphiphysin II involved in early endocytic pathway.2003
- Author(s)
  H.Kajiho, K.Saito, K.Tsujita, K.Kontani, Y.Araki, H.Kurosu, T.Katada
- Journal Title
  
  Journal of Cell Science 116
  
  Pages: 4159-4168
- Data Source
  KAKENHI-PROJECT-15770106
[Journal Article] Interaction between Ski7p and Upflp is required for none-sense-mediated 3' -to-5' mRNA decay in yeast.2003
- Author(s)
  S.Takahashi, Y.Araki, T.Sakuno, T.Katada
- Journal Title
  
  The EMBO Journal 22
  
  Pages: 3951-3959
- Data Source
  KAKENHI-PROJECT-15770106
[Journal Article] Ski7p G protein interacts with the exosome and the Ski complex for 3'-to-5' mRNA decay in yeast.2001
- Author(s)
  Araki Y, et al.
- Journal Title
  
  EMBO J. 20
  
  Pages: 4684-4693
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12144202
[Journal Article] Ski7p G protein interacts with the exosome and the Ski complex for 3'-to-5' mRNA decay in yeast.2001
- Author(s)
  Araki Y, et al.
- Journal Title
  
  EMBO J. 20
  
  Pages: 4684-4693
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854025
[Journal Article] Ski7p G protein interacts with the exosome and the Ski complex for 3'-to 5' mRNA decay in yeast.2001
- Author(s)
  Araki Y, et al.
- Journal Title
  
  EMBO J. 20
  
  Pages: 4684-4693
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13854025
[Presentation] TORC1が活性化経路を二つ有する意義2020
- Author(s)
  荒木保弘
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06111
[Presentation] 細胞内二大分解系を司るTORC1の液滴形成による活性制御2019
- Author(s)
  荒木保弘，野田健司
- Organizer
  第92回日本生化学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06111
[Presentation] TORC1 の液滴形成による活性維持機構2019
- Author(s)
  荒木保弘，野田健司
- Organizer
  大阪大学蛋白研セミナー/第 3 回 LLPS 研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06111
[Presentation] 二つのTORC1活性化経路を失った酵母変異株からわかったこと2019
- Author(s)
  荒木保弘，鈴木清太郎，田中信武，野田健司
- Organizer
  第９回TOR研究会
- Data Source
  KAKENHI-PROJECT-18K06111
[Presentation] 酵母はいかにして栄養を感知するか2018
- Author(s)
  荒木保弘
- Organizer
  第22回酵母合同シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18K06111
[Presentation] TORC1 はアミノ酸合成を直接制御する2018
- Author(s)
  荒木保弘，野田健司
- Organizer
  第11回オートファジー研究会
- Data Source
  KAKENHI-PROJECT-18K06111
[Presentation] TORC1はセリン合成経路の促進を介して細胞増殖を司る2018
- Author(s)
  荒木保弘, 河村崚介, 北谷匠, 澤田崚平, 野田健司
- Organizer
  第８回TOR研究会
- Data Source
  KAKENHI-PROJECT-18K06111
[Presentation] Gtr/Ego-independent TORC1 activation is achieved through a glutamine-sensitive interaction with Pib2 on the vacuolar membrane2018
- Author(s)
  Araki Y, Ukai H, Kira S, Noda T
- Organizer
  Nutrient signaling, Cold Spring Habor meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06111
[Presentation] Identification of a novel component required for autophagy-specific PI3K complex integrity in yeast2012
- Author(s)
  Yasuhiro Araki、Wei-chi Ku、Yasushi Ishihama、Yoshinori Ohsumi
- Organizer
  The 6th International Symposium on Autophagy 2012
- Place of Presentation
  Bankoku Shinyokan,Okinawa
- Data Source
  KAKENHI-PROJECT-23890059
[Presentation] Identification of a novel component required for autophagy-specific PI3K complex integrity in yeast2012
- Author(s)
  Yasuhiro Araki
- Organizer
  The 6th International Symposium on Autophagy 2012
- Place of Presentation
  Bankoku Shinyokan, Okinawa
- Data Source
  KAKENHI-PROJECT-23890059
[Presentation] p25 is a novel component required for autophagy-specific PI3K complex integrity in yeast2012
- Author(s)
  荒木保弘、Wei-chi Ku、石濱泰、大隅良典
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡、福岡県
- Data Source
  KAKENHI-PROJECT-23890059
[Presentation] p25 is a novel component required for autophagy-specific PI3K complex integrity in yeast2012
- Author(s)
  荒木保弘
- Organizer
  第３５回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡（福岡県）
- Data Source
  KAKENHI-PROJECT-23890059
[Presentation] Identification of targets of the Atg1 protein kinase in autophagy2011
- Author(s)
  荒木保弘
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-23890059
[Presentation] Identification of targets of the Atg1 protein kinase in autophagy2011
- Author(s)
  荒木保弘、Wei-chi Ku、石濱泰、大隅良典
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、神奈川県
- Data Source
  KAKENHI-PROJECT-23890059
[Presentation] Atg38はオートファジー特異的PI3キナーゼ複合体の構成因子である
- Author(s)
  荒木保弘
- Organizer
  第7回オートファジー研究会
- Place of Presentation
  ヤマハリゾートつま恋（静岡県）
- Data Source
  KAKENHI-PROJECT-25460063
[Presentation] Atg38はオートファジー特異的PI3キナーゼ複合体の構成因子である
- Author(s)
  荒木保弘
- Organizer
  酵母遺伝学フォーラム第46回研究報告会
- Place of Presentation
  東北学院大学（宮城県）
- Data Source
  KAKENHI-PROJECT-25460063
[Presentation] Phosphorylation of Vps34 by Atg1 is required for autophagy
- Author(s)
  荒木保弘
- Organizer
  The 7th International Symposium on autophagy
- Place of Presentation
  The smoky Willow Resort, Hangshan, Anhui, China
- Year and Date
  2015-03-19 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25460063
[Presentation] PI3キナーゼの複合体特異的機能、構成因子と制御
- Author(s)
  荒木保弘
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜神奈川県
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25460063
[Presentation] オートファジーに必須なAtg1キナーゼの基質同定
- Author(s)
  荒木保弘
- Organizer
  第8回オートファジー研究会
- Place of Presentation
  シャトレーゼキングダムサッポロ　北海道
- Year and Date
  2014-11-09 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-25460063
[Presentation] PI3キナーゼ複合体のオートファジー特異的リン酸化制御
- Author(s)
  荒木保弘
- Organizer
  酵母遺伝学フォーラム第47回研究報告会
- Place of Presentation
  東京大学弥生講堂　東京都
- Year and Date
  2014-09-01 – 2014-09-03
- Data Source
  KAKENHI-PROJECT-25460063
[Presentation] A NOVEL COMPONENT OF AUTOPHAGY-SPECIFIC PHOSPHATIDYLINOSITOL 3-KINASE COMPLEX
- Author(s)
  荒木保弘
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  神戸国際展示場（兵庫県）
- Data Source
  KAKENHI-PROJECT-25460063

1. NISHINA Hiroshi (60212122)

# of Collaborated Projects: 13 results

# of Collaborated Products: 0 results
2. HOSHINO Shin-ichi (40219168)

# of Collaborated Projects: 13 results

# of Collaborated Products: 0 results
3. KATADA Toshiaki (10088859)

# of Collaborated Projects: 13 results

# of Collaborated Products: 0 results
4. KONTANI Kenji (30302615)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. KAJIHO Hiroaki (70401221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. WADA Teiji (80401389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ISHIHAMA YASUSHI

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 有坂文雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 大友孝信

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Araki Yasuhiro 荒木 保弘

荒木 保弘 アラキ ヤスヒロ

ARAKI Yasuhiro 荒木 保弘

Research Projects

Research Products

Co-Researchers

成長と増殖を司るTORC1のタンパク質分解システムを介した活性制御機構の解明Principal Investigator

Principal Investigator

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細胞成長を司るTORC1の活性化を誘導するアミノ酸感知システムの包括的理解Principal Investigator

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Elucidation of attenuation system for autophagy by phosphatasesPrincipal Investigator

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Studies on regulation of autophagosome formation by kinases andphosphatasesPrincipal Investigator

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がん原因遺伝子の検出法と治療への応用を目指したmRNA分解制御機構の解明Principal Investigator

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遺伝子発現調節としてのmRNA分解:G蛋白質Ski7と脱キャップ酵素による制御Principal Investigator

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Araki Yasuhiro 荒木保弘

荒木保弘アラキヤスヒロ

ARAKI Yasuhiro 荒木保弘