KAKU Haruki 賀来春紀

Researcher Number	60346426
Affiliation (based on the past Project Information) *help	2011 – 2016: 岡山大学, 大学病院, 講師 2010 – 2015: 岡山大学, 岡山大学病院, 講師 2010: 岡山大学, 病院, 講師 2009: 岡山大学, 大学病院, 講師 2008: Okayama University, 医学部・歯学部附属病院, 講師 2007: Okayama University, 医学部・歯学部附属病院, 助教 2005 – 2006: 岡山大学, 医学部・歯学部附属病院, 助手
Review Section/Research Field	Principal Investigator Urology Except Principal Investigator Urology
Keywords	Principal Investigator エンハンサー / CMV / SV40 / hTERT / 遺伝子発現 / 自己癌ワクチン化 / 診断法 / GFP発現プラスミド試薬 / ウイルス製剤 / 遺伝子発現プラスミド … More / 蛍光蛋白（GFP） / 癌診断 / プラスミド / 膀胱癌 / ウイルスベクター / 緑色蛍光タンパク質 / 制限増殖型アデノウイルス / テロメラーゼ・プロモーター / 遺伝子治療 / 尿路性器癌 / 腫瘍学 … More Except Principal Investigator 前立腺癌 / 遺伝子治療 / 再生医学 / 再生 / 幹細胞 / サイトカイン / REIC/Dkk-3 / REIC / 腎臓 / 再生医療 / 男性ホルモン / アンドロゲン / 免疫学 / がん / タンパク質 / 癌免疫 / STAT / 癌 / ＲＥＩＣ／Ｄｋｋ３ / 細胞傷害性Tリンパ球 / 骨髄系免疫制御細胞 / REIC/Dkk3 / 骨髄系免疫抑制細胞 / 癌ワクチン / ノックアウトマウス / 蛋白治療. / REIK/DKK-3 / 樹状細胞 / 抗癌免疫 / 腎細胞癌 / 遺伝子導入 / 生分解性ポリマー / 生分解 / テーラーメイド / ポリマー Less

尿路癌に対する次世代癌免疫療法の創成Principal Investigator
- Principal Investigator
  
  賀来春紀
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Okayama University
Establishment and applicational research of androgen producing stem cells
- Principal Investigator
  
  Sugimoto Morito
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Okayama University
Induction and isolation of renal stem cells and establishment of foundation for renal regeneration research.
- Principal Investigator
  
  Watanabe Masami
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Urology
- Research Institution
  Okayama University
A novel therapeutic strategy for prostate cancer treatment with anti-cancer immunological proteins.
- Principal Investigator
  
  NASU Yasutomo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Okayama University
Investigation of the mechanisms of personalized-cancer vaccination by REIC/Dkk-3 based gene therapy.
- Principal Investigator
  
  KUMON Hiromi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Okayama University
Development of new diagnostic methods for bladder cancer using GFP expressing adenovirus vectorPrincipal Investigator
- Principal Investigator
  
  KAKU Haruki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Okayama University
Basic and developmental research of a novel anti-tumor protein with dendritic cell-inducible activity.
- Principal Investigator
  
  NASU Yasutomo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Okayama University
The development study of the new gene therapy that assumed telomerase activity for urinary cancers.Principal Investigator
- Principal Investigator
  
  KAKU Haruki
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Okayama University
生分解性ポリマーを用いたテーラーメイド型遺伝子治療用ベクターの開発研究
- Principal Investigator
  
  NASU Yasutomo
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Urology
- Research Institution
  Okayama University

All 2014 2013 2012 2011 2010 2008 2007 2006

All Journal Article Presentation Book

[Book] Suicide gene and immuno gene therapy for prostate cancer2011
- Author(s)
  Nasu Y, Sasaki K, Kumon H, Kaku H, Watanabe M
- Publisher
  Nihon Rinsho
- Data Source
  KAKENHI-PROJECT-21390441
[Book] REIC/Dkk-3 gene therapy2011
- Author(s)
  Watanabe M, Kaku H, Huang P, Kumon H, Nasu Y
- Publisher
  Nihon Rinsho
- Data Source
  KAKENHI-PROJECT-21390441
[Book] 前立腺癌(第2 版)-基礎・臨床研究のアップデート2011
- Author(s)
  渡部昌実、賀来春紀、黄鵬、那須保友、公文裕巳
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-22591767
[Book] 前立腺癌の治療遺伝子治療自殺遺伝子・免疫遺伝子を用いた遺伝子治療2011
- Author(s)
  那須保友、佐々木克己、賀来春紀、渡部昌実、公文裕巳
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-22591767
[Book] 遺伝子治療の最先端泌尿器疾患治療の新しいストラテジー(村井勝, 奥山明彦, 内藤誠二編)2007
- Author(s)
  賀来春紀, 那須保友, 公文裕巳
- Total Pages
  793
- Publisher
  メジカルビューシャ, 東京
- Data Source
  KAKENHI-PROJECT-18591754
[Book] 泌尿器疾患治療の新しいストラテジー2007
- Author(s)
  賀来春紀, 那須保友, 公文裕巳(村井勝, 奥山明彦, 内藤誠二編)
- Total Pages
  404
- Publisher
  メジカルビュー社
- Data Source
  KAKENHI-PROJECT-17659505
[Journal Article] Significant association of the Axin2 rs2240308 single nucleotide polymorphism with the incidence of prostate cancer.2014
- Author(s)
  Chao Ma, Chunxiao Liu, Peng Huang, Haruki Kaku, Jie Chen, Kai Guo, Hideo Ueki, Akiko Sakai, Yasutomo Nasu, Hiromi Kumon, Kenji Shimizu, Masami Watanabe.
- Journal Title
  
  Oncology Letters
  
  Volume: 8 Pages: 789-794
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462479
[Journal Article] Dramatic Increase in Expression of a Transgene by Insertion of Promoters Downstream of the Cargo Gene2014
- Author(s)
  Masakiyo Sakaguchi, Masami Watanabe, Rie Kinoshita, Haruki Kaku, Hideo Ueki, Junichiro Futami, Hitoshi Murata, Yusuke Inoue, Shun-Ai Li, Peng Huang, Endy Widya Putranto, I. Made, Winarsa Ruma, Yasutomo Nasu, Hiromi Kumon, Nam-ho Huh
- Journal Title
  
  Mol. Biotechnol
  
  Volume: 56 Issue: 7 Pages: 621-630
- DOI
  10.1007/s12033-014-9738-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23360370, KAKENHI-PROJECT-24390368, KAKENHI-PROJECT-25460490, KAKENHI-PROJECT-25861425, KAKENHI-PROJECT-26290039
[Journal Article] A novel gene expression system strongly enhances the anticancer effects of a REIC/Dkk-3-encoding adenoviral vector2014
- Author(s)
  Watanabe M., Sakaguchi M., Kinoshita R., Kaku H., Ariyoshi Y., Ueki H., Tanimoto R., Ebara S., Ochiai K., Futami J., Li SA., Huang P., Nasu Y., Huh NH., Kumon H
- Journal Title
  
  Oncology Reports
  
  Volume: 31巻 Issue: 3 Pages: 1089-95
- DOI
  10.3892/or.2013.2958
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390382, KAKENHI-PROJECT-24780313, KAKENHI-PROJECT-25462479, KAKENHI-PROJECT-25861425, KAKENHI-PROJECT-26290039
[Journal Article] Cancer stem cell-likecharacteristics of a CD133+ subpopulation in the J82 human bladder cancer cell line2013
- Author(s)
  Peng Huang, Masami Watanabe,Haruki Kaku
- Journal Title
  
  Molecular and Clinical Oncology
  
  Volume: 1 Pages: 180-184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591767
[Journal Article] Clinical significance of CD24 as a predictor of bladder cancer recurrence2013
- Author(s)
  Chunxiao Liu, Shaobo Zheng, Haiyan Shen, Kai Xu, Jie Chen, Hulin Li, Yawen Xu, Abai Xu, Binshen Chen, Haruki Kaku, Yasutomo Nasu, Hiromi Kumon, Peng Huang, Masami Watanabe
- Journal Title
  
  Oncology letters
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591767
[Journal Article] Preclinical biodistribution and safety study of reduced expression in immortalized cells/Dickkopf-3-encoding adenoviral vector for prostate cancer gene therapy2012
- Author(s)
  Sugimoto M., Watanabe M., Kaku H., Li SA., Noguchi H., Ueki H., Sakaguchi M., Huh NH., Nasu Y., Kumon H
- Journal Title
  
  Oncol Rep
  
  Volume: 28巻 Issue: 5 Pages: 1645-1652
- DOI
  10.3892/or.2012.2001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390382, KAKENHI-PROJECT-24390316, KAKENHI-PUBLICLY-24117711
[Journal Article] REIC/Dkk-3-encoding adenoviral vector as a potentially effective therapeutic agent for bladder cancer.2012
- Author(s)
  Hirata et al.
- Journal Title
  
  Int J Oncol.
  
  Volume: 41 Issue: 2 Pages: 559-564
- DOI
  10.3892/ijo.2012.1503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501013, KAKENHI-PROJECT-22616004, KAKENHI-PROJECT-23370089, KAKENHI-PROJECT-23390382, KAKENHI-PROJECT-23659213, KAKENHI-PROJECT-24390368, KAKENHI-PUBLICLY-24117711
[Journal Article] Preclinical Safety and Efficacy of in Situ REIC/Dkk-3 Gene Therapy for Prostate Cancer.2012
- Author(s)
  Kawauchi K, Watanabe M, Kaku H, Huang P, Sasaki K, Sakaguchi M, Ochiai K, Huh NH, Nasu Y, Kumon H.
- Journal Title
  
  Acta Med Okayama
  
  Volume: 66(1) Pages: 7-16
- NAID
  120003850603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390441
[Journal Article] Implications of transcriptional factor, OCT-4, in human bladder malignancy and tumor recurrence2012
- Author(s)
  Huang P Chen J Wang L Na Y Kaku H.Ueki H Sasaki K Yamaguchi K Zhang K Saika T Nasu Y Watanabe M, . Kumon H
- Journal Title
  
  Med Oncol
  
  Volume: 29 Pages: 829-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591767
[Journal Article] Preclinical biodistribution and safety study of REIC/Dkk-3 encoding adenovirus vector for prostate cancer gene therapy2012
- Author(s)
  Sugimoto M Watanabe M, Kaku H, , , , , , , .Preclinical Li SA Noguchi H Ueki H Sakaguchi M Huh NH Nasu Y Kumon H
- Journal Title
  
  Oncol Rep
  
  Volume: 28 Pages: 1645-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591767
[Journal Article] A novel gene expression system for detecting viable bladder cancer cells2012
- Author(s)
  Ueki H Watanabe M, Kaku H, , , , , , , , , , . Huang P Li SA Ochiai K Hirata T Noguchi H Yamada H Takei K Nasu Y Kashiwakura Y Kumon H
- Journal Title
  
  International Journal of Oncology
  
  Volume: 41 Pages: 135-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591767
[Journal Article] REIC/Dkk-3-encoding adenoviral vector as a potentially effective therapeutic agent for bladder cancer2012
- Author(s)
  Hirata T, Watanabe M, Kaku H, Kobayashi Y, Yamada H, Sakaguchi M, Takei K, Huh NH, Nasu Y, Kumon H
- Journal Title
  
  International Journal of Oncology
  
  Volume: 41 Pages: 559-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591767
[Journal Article] Preclinical safety and efficacy of in situ REIC/Dkk-3 gene therapy for prostate cancer2012
- Author(s)
  Kawauchi K., Watanabe M., Kaku H., Huang P., Sasaki K., Sakaguchi M., Ochiai K., Huh NH., Nasu Y., Kumon H
- Journal Title
  
  Acta Med Okayama
  
  Volume: 66巻 Pages: 7-16
- NAID
  120003850603
- URL
  http://escholarship.lib.okayama-u.ac.jp/amo/vol66/iss1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390382
[Journal Article] Implications of transcriptional factor2012
- Author(s)
  Huang P, Chen J, Wang L, Na Y,Kaku H, Ueki H, Sasaki K, Yamaguchi K, Zhang K, Saika T, Nasu Y, Watanabe M, Kumon H
- Journal Title
  
  OCT-4, in human bladder malignancy and tumor recurrence
  
  Volume: 29 Pages: 829-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591767
[Journal Article] Implications of transcriptional factor, OCT-4, in human bladder malignancy and tumor recurrence.2011
- Author(s)
  Huang P, Chen J, Wang L, Na Y, Kaku H, Ueki H, Sasaki K, Yamaguchi K, Zhang K, Saika T, Nasu Y, Watanabe M, Kumon H
- Journal Title
  
  Med Oncol.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390441
[Journal Article] REIC/Dkk-3遺伝子治療2011
- Author(s)
  渡部昌実, 賀来春紀, 他
- Journal Title
  
  前立腺癌(第2版)-基礎・臨床研究のアップデート-
  
  Pages: 559-563
- Data Source
  KAKENHI-PROJECT-22591767
[Journal Article] Advanced two-step transcriptional amplification as a novel method for cancer-specific gene expression and imaging2011
- Author(s)
  Watanabe M, Ueki H, Ochiai K, Huang P, Kobayashi Y, Nasu Y, Sasaki K,Kaku H, Kashiwakura Y, Kumon H.
- Journal Title
  
  Oncol Rep
  
  Volume: 26 Pages: 769-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591767
[Journal Article] Tumor suppressor REIC/Dkk-3 interacts with the dynein light chain, Tctex-12011
- Author(s)
  Ochiai, K., Watanabe, M., Ueki, H., Huang, P., Fujii, Y., Nasu, Y., Sakaguchi, M., Huh, NH., Kashiwakura, Y., Kaku, H., and Kumon, H.
- Journal Title
  
  Biochem. Biophy. Res. Com
  
  Volume: 412(2) Issue: 2 Pages: 391-395
- DOI
  10.1016/j.bbrc.2011.07.109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791476, KAKENHI-PROJECT-23390382
[Journal Article] Single nucleotide polymorphism WRN Leu1074Phe is associated with prostate cancer susceptibility in Chinese subjects.2011
- Author(s)
  Wang L, Kaku H, Huang P, Xu K, Yang K, Zhang J, Li M, Xie L, Wang X, Sakai A, Watanabe M, Nasu Y, Shimizu K, Kumon H, Na Y.
- Journal Title
  
  Acta Med Okayama
  
  Volume: 65(5) Pages: 315-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390441
[Journal Article] Tumor suppressor REIC/Dkk-3 interacts with the dynein light chain, Tctex-1.2011
- Author(s)
  Ochiai K, Watanabe M, Ueki H, Huang P, Fujii Y, Nasu Y, Noguchi H, Hirata T, Sakaguchi M, Huh NH, Kashiwakura Y, Kaku H, Kumon H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 412(2) Pages: 391-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390441
[Journal Article] Advanced two-step transcriptional amplification as a novel method for cancer-specific gene expression and imaging.2011
- Author(s)
  Watanabe M, Ueki H, Ochiai K, Huang P, Kobayashi Y, Nasu Y, Sasaki K, Kaku H, Kashiwakura Y, Kumon H
- Journal Title
  
  Oncol Rep.
  
  Volume: 26(4) Pages: 769-75
- DOI
  10.3892/or.2011.1371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390441, KAKENHI-PROJECT-22791476
[Journal Article] A randomized phase II trial of personalized peptide vaccine plus low dose estramustine phosphate(EMP) versus standard dose EMP in patients with castration resistant prostate cancer.2010
- Author(s)
  Noguchi M, Kakuma T, Uemura H, Nasu Y, Kumon H, Hirao Y, Moriya F, Suekane S, Matsuoka K, Komatsu N, Shichijo S, Yamada A, Itoh K.
- Journal Title
  
  Cancer Immunol Immunother.
  
  Volume: 59(7) Pages: 1001-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390441
[Journal Article] Potent antitumor effects of combined therapy with a telomerase-specific, replication-competent adenovirus(OBP-301)and IL-2 in a mouse model of renal cell carcinoma2010
- Author(s)
  Huang P Kaku H, , , , , , Chen J Kashiwakura Y Saika T Nasu Y Urata Y Fujiwara T, Watanabe M, . Potent antitumor Kumon H
- Journal Title
  
  Cancer Gene Ther
  
  Volume: 17 Pages: 484-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591767
[Journal Article] Expression pattern of REIC/Dkk-3 in various cell types and the implications of the soluble form in prostatic acinar development.2010
- Author(s)
  Zhang K, Watanabe M, Kashiwakura Y, Li SA, Edamura K, Huang P, Yamaguchi K, Nasu Y, Kobayashi Y, Sakaguchi M, Ochiai K, Yamada H, Takei K, Ueki H, Huh NH, Li M, Kaku H, Na Y, Kumon H.
- Journal Title
  
  Int J Oncol
  
  Volume: 37(6) Pages: 1495-501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390441
[Journal Article] Potent antitumor effects of combined therapy with a telomerase-specific, replication-competent adenovirus(OBP-301) and IL-2 in a mouse model of renal cell carcinoma.2010
- Author(s)
  Huang P, Kaku H, Chen J, Kashiwakura Y, Saika T, Nasu Y, Urata Y, Fujiwara T, Watanabe M, Kumon H.
- Journal Title
  
  Cancer Gene Ther.
  
  Volume: 17(7) Pages: 484-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390441
[Journal Article] Direct and distant antitumor effects of a telomerase-selective oncolytic adenoviral agent, OBP-301, in a mouse prostate cancer model2008
- Author(s)
  Huang P., Watanabe M., Kaku H., Kashiwakura Y., Chen J., Saika T., Nasu Y., Fujiwara T., Urata Y., Kumon H
- Journal Title
  
  Cancer Gene Therapy 15
  
  Pages: 315-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591754
[Journal Article] 岡山大学における前立腺癌遺伝子治療研究の現況と展望 -ベーシックリサーチからトランスレーショナルリサーチへ-2007
- Author(s)
  賀来春紀, 藤原俊義, 渡部昌実, 黄鵬, 陳潔, 谷本竜太フェルナンドアバルスア, 枝村康平真鍋大輔, 江原伸, 雑賀隆史那須保友, 公文裕巳
- Journal Title
  
  西日本泌尿器科 69
  
  Pages: 221-229
- NAID
  10019994587
- Data Source
  KAKENHI-PROJECT-17659505
[Journal Article] Suicide gene therapy with adenoviral delivery of HSV-tK gene for patients withlocal recurrence of prostate cancer after hormonal therapy2007
- Author(s)
  Nasu Y., Saika T., Ebara S., Kusaka N., Kaku H., Abarzua F., Manabe D., Thompson T.C.,Kumon H
- Journal Title
  
  Mol Ther. 15
  
  Pages: 834-840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591754
[Journal Article] Routine transurethral biopsy of the bladder is not necessary to evaluate the response to bacilluscalmette-guerin therapy2007
- Author(s)
  Murakami T., Ebara S., Saika T., Irie S., Takeda K., Maki Y., Miyaji S., Manabe D., Kaku H., Nasu Y., Tsushima T., Kumon H
- Journal Title
  
  Acta Med Okayama 61
  
  Pages: 341-344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591754
[Journal Article] Heat shock proteins play a crucial role in tumor-specific apoptosis by REIC/Dkk-32007
- Author(s)
  Abarzua F., Sakaguchi M., TaniSonegawa H., Li D.W., Edamura K., Kobayashi T., Watanabe M., Kashiwakura Y., Kaku H., Saika T., Nakamura K., Nasu Y., Kumon H., Huh NH
- Journal Title
  
  Int J Mol Med. 20
  
  Pages: 37-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591754
[Journal Article] Suicide gene therapy with adenoviral delivery of HSV-tK gene for patients with local recurrence of prostate cancer after hormonal therapy2007
- Author(s)
  Nasu Y, Saika T, Ebara S, Kusaka N, Kaku H, Abarzua F, Manabe D, Thompson T.C, Kumon H
- Journal Title
  
  Mol Ther 15
  
  Pages: 834-840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17659505
[Journal Article] 前立腺癌-基礎・臨床研究のアップデート-II.臨床研究治療遺伝子治療2007
- Author(s)
  賀来春紀, 那須保友, 雑賀隆史, 公文裕巳
- Journal Title
  
  自殺遺伝子・サイトカイン遺伝子を用いた遺伝子治療 65
  
  Pages: 522-527
- Data Source
  KAKENHI-PROJECT-18591754
[Journal Article] 岡山大学における前立腺癌遺伝子治療研究の現況と展望-ベーシックリサーチからトランスレーショナルリサーチヘー2006
- Author(s)
  賀来春紀, 藤原俊義, 公文裕巳, 渡部昌実, 黄鵬, 陳潔, 谷本竜太, フェルナンドアバルスア, 枝村康平, 真鍋大輔, 江原伸, 雑賀隆史, 那須保友, 公文裕巳
- Journal Title
  
  西日本泌尿器科 69
  
  Pages: 221-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591754
[Journal Article] Combination chemotherapy with estramustine phosphate, ifosand cisplatin for hormone-refractory prostate cancer2006
- Author(s)
  Kaku H., Saika T., Tsushima T., Nagai A., Yokoyama T., Abarzua F., Ebara S., Manabe D., Nasu Y., Kumon H
- Journal Title
  
  Acta Med Okayama 60
  
  Pages: 43-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591754
[Presentation] A phase I/II study of reduced expression in immortalized cells(REIC/Dkk-3)gene therapy for prostate cancer: Challenge to establish as a cancer vaccine2013
- Author(s)
  Ariyoshi Y.,Watanabe M.,Sasaki K.,Hirata T.,Tanimoto R.,Kaku H.,Ebara S.,Watanabe T.,Nasu Y.,Kumon H.
- Organizer
  Asian Pacific Prostate Society 2013
- Place of Presentation
  Melbourne, Australia
- Data Source
  KAKENHI-PROJECT-23390382
[Presentation] A super geneexpression system strongly enhances the anticancer effects of the REIC/Dkk-3 encoding adenoviral vector2013
- Author(s)
  Watanabe M.,Sakaguchi M.,Kaku H.,Ueki H.,Ariyoshi Y.,Hirata T.,Yoshioka T.,Huang P.,Li S-A.,Nasu Y.,Huh N.,Kumon H.
- Organizer
  Annual　Meeting　of Japan Society of Gene Therapy
- Place of Presentation
  Okayama，Okayama Convention Center
- Data Source
  KAKENHI-PROJECT-23390382
[Presentation] Immunomodulation and anti-cancer activity of REIC/Dkk-3 protein2013
- Author(s)
  Huang P.,Watanabe M.,Nasu Y.,Kaku H.,and　Kumon H.
- Organizer
  European Society of Gene and Cell Therapy
- Place of Presentation
  Madrid, Spain
- Data Source
  KAKENHI-PROJECT-23390382
[Presentation] Adenovirus-mediated REIC-Dkk-3 gene therapy induces tumor antigen-specific cytotoxic T-cell activation in mouse cancer models2013
- Author(s)
  Ariyoshi Y.,Hirata T.,Watanabe M.,Tanimoto R.,Sasaki K.,Kaku H.,Ebara S.,Watanabe T.,Nasu Y.,Kumon H.
- Organizer
  Annual　Meeting　of Japan Society of Gene Therapy
- Place of Presentation
  Okayama，Okayama Convention Center
- Data Source
  KAKENHI-PROJECT-23390382
[Presentation] REIC/Dkk-3 encoding adenoviral vector as a potentially effective therapeutic agent for bladder cancer2012
- Author(s)
  Hirata T, Watanabe M, Kaku H, Ebara S, Watanabe T, Nasu Y, Kumon H
- Organizer
  日本泌尿器科学会西日本総会
- Place of Presentation
  徳島
- Year and Date
  2012-11-09
- Data Source
  KAKENHI-PROJECT-22591767
[Presentation] 前立腺癌に対する遺伝子治療 -新たな免疫療法の開発をめざした取り組み2011
- Author(s)
  佐々木克己、那須保友、渡部昌実、賀来春紀、公文裕巳
- Organizer
  第63回日本泌尿器科学会西日本総会
- Place of Presentation
  福岡
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-22591767
[Presentation] 前立腺癌の治療(総論): 「前立腺癌早期発見早期診断プロジェクト」2011
- Author(s)
  賀来春紀
- Organizer
  フォローアップ協力セミナー
- Place of Presentation
  中国・長春
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-22591767
[Presentation] 前立腺癌の治療(各論): 「前立腺癌早期発見早期診断プロジェクト」2011
- Author(s)
  賀来春紀
- Organizer
  フォローアップ協力セミナー
- Place of Presentation
  中国・長春
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-22591767
[Presentation] A phase I/IIstudy of adenovirus mediated interleukin-12 gene therapy for hormone refractory prostate cancer :2011
- Author(s)
  Sasaki K, Nasu Y, Kaku H, Watanabe M, Nose H, Kanbara D, Saika T, Kumon H
- Organizer
  An interim report American Society of Clinical Oncology 2010 Genitourinary Cancers Symposium
- Place of Presentation
  Orlando, Florida, U.S.A.
- Year and Date
  2011-02-03
- Data Source
  KAKENHI-PROJECT-22591767
[Presentation] 前立腺癌に対するREIC 遺伝子治療2011
- Author(s)
  黄鵬,渡部昌実,賀来春紀,陳潔,那須保友,公文裕巳
- Organizer
  癌免疫外科研究会
- Place of Presentation
  和歌山市
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22591767
[Presentation] Cooperative research on genetic predisposition for prostate cancer in Asia by analyzing cumulative association of SNPs-the analyses data in Japanese.2010
- Author(s)
  Kaku H.
- Organizer
  27th日韓泌尿器科会議
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22591767
[Presentation] REIC/Dkk-3 stable transfectant indicates anti-tumor phentype in mouse prostate cancer RM9 cells2008
- Author(s)
  Kaku H
- Organizer
  14^<Th>JSGT
- Place of Presentation
  Sapporo, Japan
- Year and Date
  2008-06-13
- Data Source
  KAKENHI-PROJECT-18591754
[Presentation] The present and futre of gene therapy for prostate cancer inOkayama university2007
- Author(s)
  Kaku H
- Organizer
  The 1^<st> China-Japan Urological Congress
- Place of Presentation
  Xiamen, China
- Year and Date
  2007-11-17
- Data Source
  KAKENHI-PROJECT-18591754
[Presentation] Telomerase-specific replication-selective virotherapy for prostate cancer2006
- Author(s)
  賀来春紀
- Organizer
  第12回日本遺伝子治療学会
- Place of Presentation
  東京
- Year and Date
  2006-08-26
- Data Source
  KAKENHI-PROJECT-18591754

1. NASU Yasutomo (20237572)

# of Collaborated Projects: 5 results

# of Collaborated Products: 22 results
2. WATANABE Masami (70444677)

# of Collaborated Projects: 4 results

# of Collaborated Products: 23 results
3. UEKI Hideo (90537218)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
4. KUMON Hiromi (30144760)

# of Collaborated Projects: 3 results

# of Collaborated Products: 20 results
5. FUJIWARA Toshiyoshi (00304303)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. KAGAWA Syunsuke (00362971)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. Sugimoto Morito (30613161)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. NOGUCHI HIROFUMI (50378733)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 雑賀隆史 (10314676)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
10. 黄鵬 (00610841)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
11. HUH Namho (70142023)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. SAKAGUCHI Masakiyo (70379840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
13. 小武家誠 (50452579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 江原伸 (70379741)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 枝村康平 (90535816)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. KAZUHIKO Ochiai

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. FUTAMI Jyunichirou

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAKU Haruki 賀来 春紀

Research Projects

Research Products

Co-Researchers

尿路癌に対する次世代癌免疫療法の創成Principal Investigator

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Establishment and applicational research of androgen producing stem cells

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Induction and isolation of renal stem cells and establishment of foundation for renal regeneration research.

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A novel therapeutic strategy for prostate cancer treatment with anti-cancer immunological proteins.

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Investigation of the mechanisms of personalized-cancer vaccination by REIC/Dkk-3 based gene therapy.

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Development of new diagnostic methods for bladder cancer using GFP expressing adenovirus vectorPrincipal Investigator

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Basic and developmental research of a novel anti-tumor protein with dendritic cell-inducible activity.

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The development study of the new gene therapy that assumed telomerase activity for urinary cancers.Principal Investigator

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生分解性ポリマーを用いたテーラーメイド型遺伝子治療用ベクターの開発研究

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[Book] Suicide gene and immuno gene therapy for prostate cancer2011

Author(s)

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[Book] REIC/Dkk-3 gene therapy2011

Author(s)

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[Book] 前立腺癌(第2 版)-基礎・臨床研究のアップデート2011

Author(s)

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[Book] 前立腺癌の治療 遺伝子治療 自殺遺伝子・免疫遺伝子を用いた遺伝子治療2011

Author(s)

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[Book] 遺伝子治療の最先端泌尿器疾患治療の新しいストラテジー(村井勝, 奥山明彦, 内藤誠二編)2007

Author(s)

Total Pages

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Data Source

[Book] 泌尿器疾患治療の新しいストラテジー2007

KAKU Haruki 賀来春紀

[Book] 前立腺癌の治療遺伝子治療自殺遺伝子・免疫遺伝子を用いた遺伝子治療2011