YAMANAKA Yoshitaka 山中良孝

Researcher Number	60346442
External Links
Affiliation (based on the past Project Information) *help	2002 – 2004: Okayama University Hospital, Assistant, 医学部・歯学部附属病院, 助手 2002: 岡山大学, 医学部付属病院, 助手 2002: 岡山大学, 医学部附属病院, 助手 2002: 岡山大学, 大学院・医歯学総合研究科, 助教授
Review Section/Research Field	Principal Investigator Pediatrics Except Principal Investigator Endocrinology / Pediatrics / Metabolomics / Pediatrics / Biological Sciences
Keywords	Principal Investigator BiP / HMGB1 / PTH / FGFR3 / transgenic mouse / hone organ culture / chondrocytes / Achondroplasia / 骨成長障害 / STAT1 … More / FGF recetor 3 / PLCγ / リガンド依存性 / 線維芽細胞成長因子受容体3 / 骨伸長 / 変異 / TDII / 副甲状腺ホルモン / Bip / トランスジェニックマウス / 骨器官培 / 成長軟骨 / 軟骨無形成症 … More Except Principal Investigator PTH / 軟骨細胞 / 器官培養 / 軟骨無形成症 / FGFR3 / FGF23 / XLH / Hyp / stat-1 / ATDC-5 / PTHrP / bone growth / achondroplasia / Stat1 / 骨成長障害 / STAT1 / FGF receptor 3 / アポトーシス / 骨成長 / 副甲状腺ホルモン / 線維芽細胞増殖因子受容体3型 / GSα / McCune-Albright Syndrome / phosphatonin / apoptpsis / Hypマウス / 低リン血症性くる病 / Fanconi症候群 / FGFR / 家族性低リン血症性ビタミンD抵抗性くる病 / 腫瘍性骨軟化症 / PHEX / cAMP / Gsα / McCune-Albright症候群 / bcl-2 / VPRKO / 変異FGFR3 / IGF-I / 細胞死 / 線維芽細胞成長因子受容体3 / 成長軟骨 / apoptosis / Bcl-2 / IGF-1 / Sillence / 遺伝子診断 / ビスフォスフォネート / COL1A2 / COL1A1 / ピリジノリン架橋 / DHPLC / 遺伝子解析 / Bisphosphonate / コラーゲン / 骨形成不全症 / cbfa 1 / アロマターゼ / 24,25-dihydroxyvitamin D / ビタミンD受容体ノックアウトマウス / 24,25(OH)2D3 / VDRKO / 1,25dihydroxyvitamin D / cbfa1 / runx2 / 移植 / 骨幹部 / 骨 / VDRKOマウス / FGFR-3 / Stat-1 / CFK2 / sprouty2 / 変異導入マウス / ATDC5 / shp2 / アデノウィルス / KDEL / stat1 / PLCγ / トランスジェニックマウス Less

An analysis and its translational approach of abnormal intracellular signal transduction in cartilage cells in achondroplasiaPrincipal Investigator
- Principal Investigator
  
  TANAKA Hiroyuki, 山中良孝
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Okayama University
骨形成不全症の分子病態と治療に関する研究
- Principal Investigator
  
  田中弘之
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Okayama University
Research on the function of the responsible genes for hypophosphatemic vitamin D resistant rickets and their pathogenetic mechanisms.
- Principal Investigator
  
  TANAKA Hiroyuki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Okayama University
Molecular basis on bone growth disturbance : Novel treatment for achondroplasia
- Principal Investigator
  
  INOUE Masaru
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Okayama University
骨系統疾患における軟骨骨化制御に関する研究-軟骨無形成症の病態解明・治療開発
- Principal Investigator
  
  TANAKA Hiroyuki, SEINO Yoshiki
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Okayama University
ビタミンD代謝物の新しい情報伝達機構に関する研究
- Principal Investigator
  
  清野佳紀
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Endocrinology
- Research Institution
  Okayama University
Mechanism of Bone Growth : Research on proliferation and apoptosis of growth plate chondrocyte.
- Principal Investigator
  
  SEINO Yoshiki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Endocrinology
- Research Institution
  Okayama University

All 2007 2005 2004 Other

All Journal Article Book

[Book] 骨の病気と付き合うには -本人と家族のために-2004
- Author(s)
  清野佳紀監修, 山中良孝編
- Total Pages
  237
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-16390303
[Book] 骨の病気と付き合うには -本人と家族のために-2004
- Author(s)
  清野佳紀監修, 山中良孝編
- Total Pages
  237
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-14570747
[Journal Article] Sustained phosphorylation of mutated FGFR3 is a crucial feature of genetic dwarfism and induces apoptosis of ATDC5 chondrogenic cell line via PLC γ-activated STAT1.2007
- Author(s)
  Harada D, Yamanaka Y^*, Ueda K, Nishimura R, Morishima T, Seino Y, Tanaka H.
- Journal Title
  
  Bone
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390303
[Journal Article] PTH has the potential to rescue disturbed bone growth in achondroplasia.2007
- Author(s)
  Ueda K^*, Yamanaka Y, Harada D, Yamagami E, Tanaka H, Seino Y.
- Journal Title
  
  Bone
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390303
[Journal Article] An effective case of growth hormone treatment on cartilage-hair hypoplasia.2005
- Author(s)
  Harada D, Yamanaka Y, et al.
- Journal Title
  
  Bone. 36(2)
  
  Pages: 317-322
- Data Source
  KAKENHI-PROJECT-15659247
[Journal Article] An effective case of Growth hormone Treatment on Cartilage-hair hypoplasia.2005
- Author(s)
  D Harada, Y Yamanaka, K Ueda, J Shimizu, M Inoue, Y Seino, H Tanaka
- Journal Title
  
  Bone
- Data Source
  KAKENHI-PROJECT-15659247
[Journal Article] An effective case of Growth hormone Treatment on Cartilage-hair hypoplasia.2005
- Author(s)
  D Harada, Y Yamanaka, K Ueda, J Shimizu. M Inoue, Y Seino, H Tanaka
- Journal Title
  
  Bone
- Data Source
  KAKENHI-PROJECT-14370337
[Journal Article] An effective case of growth hormone treatment on cartilage-hair hypoplasia.2005
- Author(s)
  Harada D, Yamanaka Y, et al.
- Journal Title
  
  Bone. 36(2)
  
  Pages: 317-322
- Data Source
  KAKENHI-PROJECT-16390303
[Journal Article] Development of novel therapy for achondroplasia : Use of parathyroid hormone.2005
- Author(s)
  Yamanaka Y, Tanaka H, Harada D, Ueda K, Seino Y.
- Journal Title
  
  Clinical Pediatric Endocrinology. (Suppl 23) 14
  
  Pages: 39-44
- NAID
  130004430956
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370337
[Journal Article] Development of novel therapy for achondroplasia : Use of parathyroid hormone. Clinical Pediatric Endocrinology.2005
- Author(s)
  Yamanaka Y, 他4名
- Journal Title
  
  Clinical Pediatric Endocrinology 14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370337
[Journal Article] Development of novel therapy for achondroplasia : Use of parathyroid hormone.2005
- Author(s)
  Yamanaka Y, Tanaka H, et al.
- Journal Title
  
  Clinical Pediatric Endocrinology (Suppl 23)14
  
  Pages: 39-44
- NAID
  130004430956
- Data Source
  KAKENHI-PROJECT-15659247
[Journal Article] An effective case of growth hormone treatment on cartilage-hair hypoplasia.2005
- Author(s)
  Harada D, Yamanaka Y, Ueda K, Shimizu J, Inoue M, Seino Y, Tanaka H.
- Journal Title
  
  Bone 36(2)
  
  Pages: 317-322
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370337
[Journal Article] Development of novel therapy for achondroplasia : Use of parathyroid hormone.2005
- Author(s)
  Yamanaka Y, Tanaka_H, et al.
- Journal Title
  
  Clinical Pediatric Endocrinology (Suppl 23) 14
  
  Pages: 39-44
- NAID
  130004430956
- Data Source
  KAKENHI-PROJECT-16390303
[Journal Article] An effective case of Growth hormone Treatment on Cartilage-hair hypoplasia.2005
- Author(s)
  D Harada, Y Yamanaka, K Ueda, J Shimizu, M Inoue, Y Seino, H Tanaka.
- Journal Title
  
  Bone
- Data Source
  KAKENHI-PROJECT-12137206
[Journal Article] くる病とリン代謝調節機構2004
- Author(s)
  山中良孝
- Journal Title
  
  小児科診療 67・10
  
  Pages: 120-125
- Data Source
  KAKENHI-PROJECT-16390303
[Journal Article] くる病とリン代謝調節機構2004
- Author(s)
  山中良孝
- Journal Title
  
  小児科診療 67・10
  
  Pages: 120-125
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570747
[Journal Article] 副甲状腺ホルモンを用いた軟骨無形成症の新規治療法の開発2004
- Author(s)
  山中良孝
- Journal Title
  
  内分泌・糖尿病科 19・3
  
  Pages: 268-275
- Data Source
  KAKENHI-PROJECT-14570747
[Journal Article] 副甲状腺ホルモンを用いた軟骨無形成症の新規治療法の開発2004
- Author(s)
  山中良孝
- Journal Title
  
  内分泌・糖尿病科 19・3
  
  Pages: 268-275
- Data Source
  KAKENHI-PROJECT-16390303
[Journal Article] 山中良孝2004
- Author(s)
  山中良孝
- Journal Title
  
  内分泌・糖尿病科 19・3
  
  Pages: 268-275
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570747
[Journal Article] PTH has the potential to rescue disturbed bone growth in achondroplasia.
- Author(s)
  Ueda K, Yamanaka Y, Harada D, Ymagami E, Tanaka H, Seino Y.
- Journal Title
  
  Bone (in press)
- Data Source
  KAKENHI-PROJECT-16390303
[Journal Article] Sustained phosphorylation of mutated FGFR3 is a crucial feature of genetic dwarfism and induces apoptosis of ATDC5 chondrogenic cell line via PLCγ-activated STAT1.
- Author(s)
  Ueda K, Yamanaka Y, Harada D, Ymagami E, Tanaka H, Seino Y.
- Journal Title
  
  Bone (in press)
- Data Source
  KAKENHI-PROJECT-16390303
[Journal Article] PTH has the potential to rescue disturbed bone growth in achondroplasia.
- Author(s)
  Ueda K^*, Yamanaka Y, Harada D, Yamagami E, Tanaka H, Seino Y
- Journal Title
  
  Bone 2007 (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390303
[Journal Article] Sustained phosphorylation of mutated FGFR3 is a crucial feature of genetic dwarfism and induces apoptosis of ATDC5 chondrogenic cell line via PLC γ-activated STAT1.
- Author(s)
  Harada D, Yamanaka Y^*, Ueda K, Nishimura R, Morishima T, Seino Y, Tanaka H.
- Journal Title
  
  Bone 2007 (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390303

1. TANAKA Hiroyuki (80231413)

# of Collaborated Projects: 9 results

# of Collaborated Products: 13 results
2. INOUE Masaru (20253023)

# of Collaborated Projects: 6 results

# of Collaborated Products: 4 results
3. SEINO Yoshiki (80028620)

# of Collaborated Projects: 5 results

# of Collaborated Products: 5 results
4. NINOMIYA Shinsuke (10325110)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results

YAMANAKA Yoshitaka 山中 良孝

Research Projects

Research Products

Co-Researchers

An analysis and its translational approach of abnormal intracellular signal transduction in cartilage cells in achondroplasiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

骨形成不全症の分子病態と治療に関する研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on the function of the responsible genes for hypophosphatemic vitamin D resistant rickets and their pathogenetic mechanisms.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular basis on bone growth disturbance : Novel treatment for achondroplasia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

骨系統疾患における軟骨骨化制御に関する研究-軟骨無形成症の病態解明・治療開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ビタミンD代謝物の新しい情報伝達機構に関する研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of Bone Growth : Research on proliferation and apoptosis of growth plate chondrocyte.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 骨の病気と付き合うには -本人と家族のために-2004

Author(s)

Total Pages

Publisher

Data Source

[Book] 骨の病気と付き合うには -本人と家族のために-2004

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Sustained phosphorylation of mutated FGFR3 is a crucial feature of genetic dwarfism and induces apoptosis of ATDC5 chondrogenic cell line via PLC γ-activated STAT1.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] PTH has the potential to rescue disturbed bone growth in achondroplasia.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] An effective case of growth hormone treatment on cartilage-hair hypoplasia.2005

Author(s)

Journal Title

Data Source

[Journal Article] An effective case of Growth hormone Treatment on Cartilage-hair hypoplasia.2005

Author(s)

Journal Title

Data Source

[Journal Article] An effective case of Growth hormone Treatment on Cartilage-hair hypoplasia.2005

Author(s)

Journal Title

Data Source

[Journal Article] An effective case of growth hormone treatment on cartilage-hair hypoplasia.2005

Author(s)

YAMANAKA Yoshitaka 山中良孝