Sakaue Motoharu 坂上元栄

… Alternative Names

坂上元栄サカウエモトハル

SAKAUE Motohara 坂上元栄

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Researcher Number	60348589
Other IDs
Affiliation (Current)	2025: 麻布大学, 獣医学部, 教授
Affiliation (based on the past Project Information) *help	2025: 麻布大学, 獣医学部, 教授 2018 – 2019: 麻布大学, 獣医学部, 教授 2017: 麻布大学, 獣医学部, 准教授 2009 – 2011: Azabu University, 獣医学部, 准教授 2007 – 2008: Azabu University, 獣医学部, 講師 2006: 北里大学, 薬学部, 講師
Review Section/Research Field	Principal Investigator Applied veterinary science / Basic Section 42020:Veterinary medical science-related / Veterinary medical science / Environmental pharmacy
Keywords	Principal Investigator 神経細胞死 / 脳由来神経栄養因子 / TrkB / 小脳顆粒細胞 / 脳由来神経影響因子 / メラノサイト / 毛包 / 色素幹細胞 / バルジ / 毛色 … More / グリア細胞 / ACh / ChAT / AChE / メチル水銀 / 神経細胞腫由来B35細胞 / 小脳粒細胞 / ラット / 神経芽細胞腫由来B35細胞 / 初代培養系 / 3,4-dihydro-5-[4-(1-piperidinyl)butoxy]-1(2H)-isoquinolinorle / glutathione / IMR-32 / 活性酸素種 / poly(ADP-ribose)polymerase / 小脳初代培養系 / 神経細胞変性モデル / 3,4-dihydro-5-[4-(1-piperidiny1)butoxy]-1(2H)-isoquinolinone / グルタチオン Less

動物模様における白色毛発生機序に関する研究Principal Investigator
- Principal Investigator
  
  坂上元栄
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Azabu University
Possibility of regulation for functions of glial cells through acethylcholine-related enzymesPrincipal Investigator
- Principal Investigator
  
  Sakaue Motoharu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Veterinary medical science
- Research Institution
  Azabu University
The novel effect of brain-derived neurotrophic factor : elucidation of the mechanism of the accelerating effect on methylmercury-induced neuronal cell deathPrincipal Investigator
- Principal Investigator
  
  SAKAUE Motoharu
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied veterinary science
- Research Institution
  Azabu University
Study for accelerating effect of brain-derived neurotrophic factor on methylmercury-induced neuronal deathPrincipal Investigator
- Principal Investigator
  
  SAKAUE Motohara
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied veterinary science
- Research Institution
  Azabu University
PARP阻害剤の神経細胞保護作用機序の解明と神経細胞変性疾患予防への応用可能性Principal Investigator
- Principal Investigator
  
  坂上元栄
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Azabu University
  Kitasato University

All 2020 2019 2018 2011 2010 2009

All Journal Article Presentation

[Journal Article] Immunohistochemical analysis for acetylcholinesterase and choline acetyltransferase in mouse cerebral cortex after traumatic brain injury2020
- Author(s)
  HORIO Tomoyo、OZAWA Aisa、KAMIIE Junichi、SAKAUE Motoharu
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 82 Issue: 6 Pages: 827-835
- DOI
  10.1292/jvms.19-0551
- NAID
  130007866433
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08117
[Journal Article] Acetylcholine suppresses the increase of glia fibrillary acidic protein expression via acetylcholine receptors in cAMP-induced astrocytic differentiation of rat C6 glioma cells2019
- Author(s)
  Ozawa Aisa、Kadowaki Erina、Horio Tomoyo、Sakaue Motoharu
- Journal Title
  
  Neuroscience Letters
  
  Volume: 698 Pages: 146-153
- DOI
  10.1016/j.neulet.2019.01.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08117
[Journal Article] Vitamin K has the potential to protect neurons from methylmercury-induced cell death in vitro2011
- Author(s)
  Sakaue, M., et al
- Journal Title
  
  Journal of Neuroscience Research
  
  Volume: 89 Issue: 7 Pages: 1052-1058
- DOI
  10.1002/jnr.22630
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390036, KAKENHI-PROJECT-22780271
[Journal Article] Acceleration of methylmercury-induced cell death of rat cerebellar neurons by brain-derived neurotrophic factor in vitro.2009
- Author(s)
  Sakaue M, Mori N, Makita M, Fujishima K, Hara S, Arishima K, Yamamoto M.
- Journal Title
  
  Brain Res. 1273
  
  Pages: 155-162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20780221
[Journal Article] Acceleration of methylmercury-induced cell death of rat cerebellar neurons by brain-derived neurotrophic factor in vitro2009
- Author(s)
  Sakaue M., et.al.
- Journal Title
  
  Brain Research (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20780221
[Presentation] 脳損傷モデルマウスにおけるastrocyte・microglia でのacetylcholinesterase およびcholine acetyltransferase 局在2018
- Author(s)
  ○堀尾朋世，小澤秋沙, 池本美貴, 中内維彌, 佐藤幸妃, 豊田紗千乃，坂上元栄
- Organizer
  第123回日本解剖学会総会・全国学術集会，東京
- Data Source
  KAKENHI-PROJECT-17K08117
[Presentation] BDNFのメチル水銀誘導性神経細胞死促進作用における細胞内GSHの関与の可能性2010
- Author(s)
  牧武宏, 坂上元栄、金子拓矢、小澤秋沙、関口仁美、邉見奈津子、門脇絵里奈、山本雅子、有嶋和義
- Organizer
  日本獣医学会第150回学術集会
- Place of Presentation
  帯広畜産大学(帯広)
- Year and Date
  2010-09-18
- Data Source
  KAKENHI-PROJECT-22780271
[Presentation] BDNFによるメチル水銀誘導性神経細胞死促進作用における細胞内GSHの関与の可能性2010
- Author(s)
  牧武宏, 坂上元栄, 金子拓矢, 小澤秋沙, 関口仁美, 邉見奈津子, 門脇絵里奈, 山本雅子, 有嶋和義
- Organizer
  日本獣医学会第150回学術集会
- Place of Presentation
  帯広畜産大学(帯広)
- Data Source
  KAKENHI-PROJECT-22780271

1. 小澤秋沙 (80803171)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. MAKI Takehiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Sakaue Motoharu 坂上 元栄

坂上 元栄 サカウエ モトハル

SAKAUE Motohara 坂上 元栄

Research Projects

Research Products

Co-Researchers

動物模様における白色毛発生機序に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Possibility of regulation for functions of glial cells through acethylcholine-related enzymesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The novel effect of brain-derived neurotrophic factor : elucidation of the mechanism of the accelerating effect on methylmercury-induced neuronal cell deathPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study for accelerating effect of brain-derived neurotrophic factor on methylmercury-induced neuronal deathPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

PARP阻害剤の神経細胞保護作用機序の解明と神経細胞変性疾患予防への応用可能性Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Immunohistochemical analysis for acetylcholinesterase and choline acetyltransferase in mouse cerebral cortex after traumatic brain injury2020

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Acetylcholine suppresses the increase of glia fibrillary acidic protein expression via acetylcholine receptors in cAMP-induced astrocytic differentiation of rat C6 glioma cells2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Vitamin K has the potential to protect neurons from methylmercury-induced cell death in vitro2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Acceleration of methylmercury-induced cell death of rat cerebellar neurons by brain-derived neurotrophic factor in vitro.2009

Author(s)

Journal Title

Data Source

[Journal Article] Acceleration of methylmercury-induced cell death of rat cerebellar neurons by brain-derived neurotrophic factor in vitro2009

Author(s)

Journal Title

Data Source

[Presentation] 脳損傷モデルマウスにおけるastrocyte・microglia でのacetylcholinesterase およびcholine acetyltransferase 局在2018

Author(s)

Organizer

Data Source

[Presentation] BDNFのメチル水銀誘導性神経細胞死促進作用における細胞内GSHの関与の可能性2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] BDNFによるメチル水銀誘導性神経細胞死促進作用における細胞内GSHの関与の可能性2010

Author(s)

Organizer

Place of Presentation

Data Source

Sakaue Motoharu 坂上元栄

坂上元栄サカウエモトハル

SAKAUE Motohara 坂上元栄