yoshida chiharu 吉田千春

… Alternative Names

YOSHIDA Chiharu 吉田千春

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Researcher Number	60360666
Other IDs
Affiliation (Current)	2025: 地方独立行政法人大阪府立病院機構大阪母子医療センター(研究所), 病因病態部門, 主任研究員
Affiliation (based on the past Project Information) *help	2017 – 2024: 地方独立行政法人大阪府立病院機構大阪母子医療センター(研究所), 病因病態部門, 主任研究員 2016: 地方独立行政法人大阪府立病院機構大阪府立母子保健総合医療センター(研究所), 病因病態部門, 主任研究員 2012 – 2015: 地方独立行政法人大阪府立病院機構大阪府立母子保健総合医療センター(研究所), その他部局等, 研究員 2012: 地方独立行政法人大阪府立病院機構大阪府立母子保健総合医療センター(研究所), 研究員 2011: 地方独立行政法人大阪府立病院機構大阪府立母子保健総合医療センター(研究所), 病因病態部門, 研究員 … More 2010: 地方独立行政法人大阪府立病院機構大阪府立母子保健総合医療センター(研究所), 病院病態部門, 研究員 2009: 研究員 2008: 地方独立行政法人大阪府立病院機構, 大阪府立母子保健総合医療センター(研究所), 研究員 2007: Research Institute, Osaka Medical Center for Maternal and Child Health, 病因病態部門, 研究員 2005 – 2006: 地方独立行政法人大阪府立病院機構大阪府立母子保健総合医療センター(研究所), 病因病態部門, 研究員 2004: 独立行政法人理化学研究所, ボディプラン研究グループ, 研究員 2003: 独立行政法人理化学研究所, ボディプラン研究グループ, 基礎科学特別研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 44020:Developmental biology-related / Developmental biology / Dermatology / System genome science Except Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Developmental biology / Biological Sciences
Keywords	Principal Investigator マウス / 神経管閉鎖不全 / 表皮分化 / 表皮形成 / 二分脊椎 / 神経管閉鎖 / 遺伝子改変マウス / 表皮 / トランスジェニックマウス / 転写制御 … More / Wnt / 核内局在制御 / 分子輸送 / 先天異常 / 上皮形成 / ノンカノニカル / 脱ユビキチン化 / カノニカルWnt経路 / 核-細胞質輸送 / 顕在性二分脊椎 / 核内局在 / 遺伝子欠損マウス / 脱ユビキチン酵素 / 発生 / 細胞分化 / マウス胎児 / EB細胞 / 表皮細胞 / 表皮細胞層 / Wnt経路 / イメージング / 表皮外胚葉 / 神経上皮 / マイクロアレイ / 遺伝学 / 発生・分化 / 発生分化 / Dickkopf1遺伝子 / canonicalシグナル / 臓側内胚葉 / Foxa2遺伝子 / Otx2遺伝子 / 前後軸 / DKK1遺伝子 / 前脳形成 / canonical シゲナル / mdkk1 / 制御調節 / 軸決定 / 前方臓側内胚葉 / ホメオボックス / ノックアウトマウス / 前後軸形成 / Dickkopf1 / canonical / Otx2 … More Except Principal Investigator マウス / 二分脊椎 / 表皮分化 / 前後軸 / 核-細胞質輸送 / 哺乳動物 / 先天異常 / 遺伝子改変マウス / 口蓋裂疾患 / 遺伝子欠損マウス / 表皮癒合 / 神経管閉鎖不全 / 疾患モデルマウス / 口唇口蓋裂 / 上皮癒合 / ライブイメージング / 細胞動態 / ライヘルト膜 / 着床 / 前後軸形成 / マウス胚 / ラミニン / 基底膜 / 細胞外マトリックス / 発生・分化 / uterus / extracellular matrix / basement membrane / morphogenesis / mouse / anterior-posterior axis / micro-environments / 前脳形成 / Dkk1 / ゲノム / 進化プロセス / Wntシグナル / BAC Less

神経管閉鎖過程におけるカノニカルWnt経路に依存したGRHL3の核内局在と機能の制御機構Principal Investigator
- Principal Investigator
  
  吉田千春
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Osama Woman's and Children's Hospital
Identification of partner molecules that bind directly to GRHL3 factors during epidermal differentiation.
- Principal Investigator
  
  持田京子
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Osama Woman's and Children's Hospital
Identification of partner molecules that bind directly to GRHL3 factors during epidermal differentiation.Principal Investigator
- Principal Investigator
  
  Yoshida Chiharu
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Osama Woman's and Children's Hospital
Elucidation of the common etiology of spina bifida and cleft palate caused by epithelial fusion defects.
- Principal Investigator
  
  Mochida Kyoko
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Osama Woman's and Children's Hospital
Studies on roles of extracellular microenvironments in the body axis formation
- Principal Investigator
  
  Matsuo Isao
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Developmental biology
- Research Institution
  Osama Woman's and Children's Hospital
Fate specification coupled to neural tube closure between surface ectoderm and neural ectoderm.Principal Investigator
- Principal Investigator
  
  YOSHIDA Chiharu
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Research Institute, Osaka Medical Center for Maternal and Child Health
Comprehensive analysis of the ectoderm differentiation using the system imagingPrincipal Investigator
- Principal Investigator
  
  YOSHIDA Chiharu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  System genome science
- Research Institution
  Research Institute, Osaka Medical Center for Maternal and Child Health
比較ゲノム解析による軸決定進化プロセスの解明
- Principal Investigator
  
  MATSUO Isao
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Research Institute, Osaka Medical Center for Maternal and Child Health
器官形成過程におけるWnt関連因子の機能解析Principal Investigator
- Principal Investigator
  
  吉田千春
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Developmental biology
- Research Institution
  Research Institute, Osaka Medical Center for Maternal and Child Health
マウス胚の前後軸決定機構におけるWntシグナルの役割Principal Investigator
- Principal Investigator
  
  吉田千春
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Developmental biology
- Research Institution
  Research Institute, Osaka Medical Center for Maternal and Child Health
  The Institute of Physical and Chemical Research

[Book] 実験モデルマウスを用いた二分脊椎発症のメカニズムの解明2015
- Author(s)
  木村-吉田千春
- Publisher
  Brain and Spinal Cord B&C
- Data Source
  KAKENHI-PROJECT-25461720
[Book] ヘパラン硫酸鎖を介したFGF シグナルの局所的な受容機構, 細胞工学312012
- Author(s)
  松尾勲、木村-吉田千春、下川佳世
- Data Source
  KAKENHI-PROJECT-22510221
[Book] FGFシグナル制御の新たな制御機構-新規な活性調節分子の発見と関連疾患治療の最先端「基礎の基礎」, 細胞工学312012
- Author(s)
  松尾勲、後藤典子、下川佳世、木村-吉田千春
- Data Source
  KAKENHI-PROJECT-22510221
[Book] Wnt シグナルとマウス前後軸決定~Wnt 拮抗因子Dickkopf1 遺伝子に着目して~, 医学のあゆみ2010
- Author(s)
  木村-吉田千春、平松竜司、松尾勲
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-22510221
[Book] BET ファミリーとエピジェネティクな遺伝子発現制御機構2010
- Author(s)
  爪麻美、木村-吉田千春、松尾勲
- Publisher
  大阪府立母子保健総合医療センター雑誌
- Data Source
  KAKENHI-PROJECT-22510221
[Book] マウス胚における前後軸形成機構の解析, プレインサイエンス・レビュー20092009
- Author(s)
  木村-吉田千春
- Publisher
  クバプロ
- Data Source
  KAKENHI-PROJECT-20017028
[Book] 細胞工学2004
- Author(s)
  木村-吉田千春, 松尾勲
- Total Pages
  4
- Data Source
  KAKENHI-PROJECT-15770151
[Book] マウスの胚において細胞膜表面のヘパラン硫酸鎖はFGF シグナルの局所的な受容に働く, ライフサイエンス新着論文レビュー
- Author(s)
  下川佳世、木村-吉田千春、松尾勲
- URL
  http://first.lifesciencedb.jp/archives/3537(2011)
- Data Source
  KAKENHI-PROJECT-22510221
[Journal Article] USP39 is essential for mammalian epithelial morphogenesis through upregulation of planar cell polarity components2022
- Author(s)
  Kimura-Yoshida C, Mochida K, Kanno SI, Matsuo I.
- Journal Title
  
  Communications Biology
  
  Volume: 378 Issue: 1 Pages: 1-18
- DOI
  10.1038/s42003-022-03254-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06685, KAKENHI-PROJECT-19K08291, KAKENHI-PROJECT-21K19467, KAKENHI-PUBLICLY-21H05794, KAKENHI-PROJECT-19H03238
[Journal Article] Identification of Cell Autonomous and Non-Cell Autonomous Functions of Heparan Sulfate Glycosaminoglycan Chains by Creating Chimeric Mouse Embryos2022
- Author(s)
  Matsuo I, Kimura-Yoshida C.
- Journal Title
  
  Methods in molecular biology.
  
  Volume: 2303 Pages: 579-593
- DOI
  10.1007/978-1-0716-1398-6_44
- ISBN
  9781071613979, 9781071613986
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06685, KAKENHI-PROJECT-19H03238
[Journal Article] Developmental and mechanical roles of Reichert's membrane in mouse embryos2022
- Author(s)
  Isao Matsuo, Chiharu Kimura-Yoshida, Yoko Ueda.
- Journal Title
  
  Philos Trans R. Soc Lond B Biol Sci.
  
  Volume: 377 Issue: 1865 Pages: 20210257-20210257
- DOI
  10.1098/rstb.2021.0257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06685, KAKENHI-PROJECT-21K19467, KAKENHI-PUBLICLY-21H05794, KAKENHI-PROJECT-19H03238
[Journal Article] BET proteins are essential for the specification and maintenance of the epiblast lineage in mouse preimplantation embryos.2022
- Author(s)
  Tsume-Kajioka M, Kimura-Yoshida C, Mochida K, Ueda Y, Matsuo I
- Journal Title
  
  BMC Biology
  
  Volume: 20 Issue: 1 Pages: 01251-0
- DOI
  10.1186/s12915-022-01251-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10202, KAKENHI-PROJECT-18K15738, KAKENHI-PROJECT-19K06685, KAKENHI-PROJECT-19K08291, KAKENHI-PROJECT-21K06194, KAKENHI-PROJECT-21K19467, KAKENHI-PROJECT-19H03238, KAKENHI-PUBLICLY-21H05794
[Journal Article] Intrauterine pressures adjusted by Reichert’s membrane are crucial for early mouse morphogenesis.2020
- Author(s)
  Yoko Ueda, Chiharu Kimura-Yoshida, Kyoko Mochida, Mami Tsume, Yoshitaka Kameo, Taiji Adachi, Olivier Lefebvre, Ryuji Hiramatsu and Isao Matsuo
- Journal Title
  
  Cell Reports
  
  Volume: 31 Issue: 7 Pages: 107637-107637
- DOI
  10.1016/j.celrep.2020.107637
- NAID
  120006951713
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04771, KAKENHI-PROJECT-17K10202, KAKENHI-PROJECT-19K06397, KAKENHI-ORGANIZER-15H05856, KAKENHI-PUBLICLY-19H04798, KAKENHI-PROJECT-19H03238, KAKENHI-INTERNATIONAL-15K21726, KAKENHI-PROJECT-19K06685, KAKENHI-PROJECT-19K08291, KAKENHI-PROJECT-18K15738
[Journal Article] Competition for Mitogens Regulates Spermatogenic Stem Cell Homeostasis in an Open Niche2019
- Author(s)
  Kitadate Y., Jorg DJ., Tokue M,. Maruyama A., Ishikawa R., Tsuchiya S., Segi-Nishida E., Nakagawa T., Uchida A., Kimura-Yoshida C., Mizuno S., Sugiyama F., Azami T., Ema M., Noda C., Kobayashi S., Matsuo I., Kanai Y., Nagasawa T., Sugimoto Y., Takahashi S., Simons BD., Yoshida S.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 24 Issue: 1 Pages: 79-92
- DOI
  10.1016/j.stem.2018.11.013
- NAID
  120007128265
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07424, KAKENHI-PROJECT-17K08316, KAKENHI-ORGANIZER-15H05897, KAKENHI-PUBLICLY-17H05783, KAKENHI-PLANNED-18H05551, KAKENHI-PROJECT-16H02507, KAKENHI-PROJECT-15K15408, KAKENHI-PLANNED-25114002, KAKENHI-PROJECT-19K06685, KAKENHI-PROJECT-19K22503, KAKENHI-PLANNED-15H05905, KAKENHI-PUBLICLY-18H04886, KAKENHI-PROJECT-17H03990, KAKENHI-PROJECT-19J22868, KAKENHI-PUBLICLY-18H04771, KAKENHI-PLANNED-18H05552, KAKENHI-PROJECT-17H01501, KAKENHI-PROJECT-26291053, KAKENHI-PUBLICLY-16H01251
[Journal Article] Cytoplasmic localization of GRHL3 upon epidermal differentiation triggers cell shape change for epithelial morphogenesis2018
- Author(s)
  Chiharu Kimura-Yoshida, Kyoko Mochida, Masa-aki Nakaya, Takeomi Mizutani and Isao Matsuo
- Journal Title
  
  Nature Communications
  
  Volume: 9(1) Issue: 1 Pages: 4059-4059
- DOI
  10.1038/s41467-018-06171-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05783, KAKENHI-PROJECT-15K15408, KAKENHI-PUBLICLY-18H04771, KAKENHI-PROJECT-26291053
[Journal Article] Cre-loxPシステムを用いた表皮形成におけるβ-cateninコンディショナルノックアウトマウスの作製と表現型解析2016
- Author(s)
  木村-吉田千春
- Journal Title
  
  大阪府立母子保健総合医療センター雑誌
  
  Volume: 32 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461720
[Journal Article] Coordinately Co-opted Multiple Transposable Elements Constitute an Enhancer for wnt5a Expression in the Mammalian Secondary Palate.2016
- Author(s)
  Nishihara H., Kobayashi N., Kimura-Yoshida C., Yan K., Bormuth O., Ding Q., Nakanishi A., Sasaki T., Hirakawa M., Sumiyama K., Furuta Y., Tarabykin V., Matsuo I., and Okada N.
- Journal Title
  
  PLoS Genet.
  
  Volume: 12(10) Issue: 10 Pages: 1-17
- DOI
  10.1371/journal.pgen.1006380
- NAID
  120005997729
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01456, KAKENHI-PROJECT-26291053, KAKENHI-PROJECT-26291075, KAKENHI-PROJECT-25461720, KAKENHI-PROJECT-15K15408, KAKENHI-PROJECT-26840117
[Journal Article] Fate Specification of Neural Plate Border by Canonical Wnt Signaling and Grhl3 is Crucial for Neural Tube Closure2015
- Author(s)
  Chiharu Kimura-Yoshida, Kyoko Mochida, Kristina Ellwanger, Christof Niehrs, Isao Matsuo
- Journal Title
  
  EBioMedicine
  
  Volume: 未定 Issue: 6 Pages: 513-527
- DOI
  10.1016/j.ebiom.2015.04.012
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461720, KAKENHI-PROJECT-15K15408
[Journal Article] Extracellular distribution of diffusible growth factors controlled by heparan sulfate proteoglycans during mammalian embryogenesis.2014
- Author(s)
  Isao Matsuo and Chiharu Kimura-Yoshida.
- Journal Title
  
  Philosophical transactions of the Royal Society of London. Series B, Biological sciences
  
  Volume: 369 Issue: 1657 Pages: 20130545-20130545
- DOI
  10.1098/rstb.2013.0545
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461720, KAKENHI-PROJECT-26291053
[Journal Article] ヘパラン硫酸鎖によるFGFシグナルの細胞外での活性制御2014
- Author(s)
  松尾勲、木村-吉田千春
- Journal Title
  
  大阪府立母子保健総合医療センター雑誌
  
  Volume: 30 Pages: 6-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26291053
[Journal Article] Extracellular modulation of Fibroblast Growth Factor signaling through heparan sulfate proteoglycans in mammalian development.2013
- Author(s)
  Matsuo I, Kimura-Yoshida C.
- Journal Title
  
  Current opinion in genetics & development.
  
  Volume: 24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510221
[Journal Article] External mechanical cues trigger the establishment of the anterior-posterior axis in early mouse embryos2013
- Author(s)
  Ryuji Hiramatsu et al.
- Journal Title
  
  Developmental Cell
  
  Volume: 27 Issue: 2 Pages: 131-144
- DOI
  10.1016/j.devcel.2013.09.026
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24116713, KAKENHI-PROJECT-25461720
[Journal Article] Extracellular modulation of Fibroblast Growth Factor signaling through heparan sulfate proteoglycans in mammalian development2013
- Author(s)
  Isao Matsuo and Chiharu Kimura-Yoshida
- Journal Title
  
  Curr. Opin. Genet. Dev
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510221
[Journal Article] Extracellular modulation of Fibroblast Growth Factor signaling through heparan sulfate proteoglycans in mammalian development2013
- Author(s)
  Isao Matsuo and Chiharu Kimura-Yoshida
- Journal Title
  
  Current Opinion in Genetics & Development
  
  Volume: 23 Issue: 4 Pages: 399-407
- DOI
  10.1016/j.gde.2013.02.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461720, KAKENHI-PUBLICLY-24116713
[Journal Article] へパラン硫酸鎖を介したFGFシグナルの局所的な受容機構2012
- Author(s)
  松尾勲、木村ｰ吉田千春、下川佳世
- Journal Title
  
  細胞工学
  
  Volume: 31 Pages: 426-431
- Data Source
  KAKENHI-PROJECT-22510221
[Journal Article] Brd2 is required for cell cycle exit and neuronal differentiation through the E2F1 pathway in mouse neuroepithelial cells.2012
- Author(s)
  Tsume M, Kimura-Yoshida C, Mochida K, Shibukawa Y, Amazaki S, Wada Y, Hiramatsu R, Shimokawa K, Matsuo I.
- Journal Title
  
  Biochemical and biophysical research communications.
  
  Volume: 425 Pages: 762-768
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510221
[Journal Article] Brd2 is required for cell cycle exit and neuronal differentiation through the E2F1 pathway in mouse neuroepithelial cells2012
- Author(s)
  Mami Tsume, Chiharu Kimura-Yoshida, Kyoko Mochida, Yukinao Shibukawa, Saori Amazaki, Yoshinao Wada, Ryuji Hiramatsu, Kayo Shimokawa, and Isao Matsuo
- Journal Title
  
  Biochemical Biophysical Research Communications
  
  Volume: 425 Pages: 762-768
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510221
[Journal Article] A genetic study of the effects of reduced Frs2α gene dosage in exostoses development and cartilage abnormalities observed in Ext2 heterozygous mutant mice. Khondokar Nasirujjaman2011
- Author(s)
  Chiharu Kimura-Yoshida, Noriko Gotoh, Ryuji Hiramatsu and Isao Matsuo
- Journal Title
  
  Journal of Osaka Medical Center & Research Institute for Maternal & Child Health
  
  Volume: 26 Pages: 101-108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510221
[Journal Article] Cell surface heparan sulfate chains regulate local reception of FGF signaling in the mouse embryo2011
- Author(s)
  Kayo Shimokawa, Chiharu. Kimura-Yoshida, Naoko Nagai, Kazuhiro Mukai, Kazumi Matsubara, Hideto Watanabe, Yoichi Matsuda, Kyoko Mochida and Isao Matsuo
- Journal Title
  
  Developmental Cell
  
  Volume: 21 Pages: 257-272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510221
[Journal Article] Wntシグナルとマウス前後軸決定-Wnt拮抗因子Dickkopf 1遺伝子に着目して2010
- Author(s)
  木村-吉田千春、平松竜司、松尾勲
- Journal Title
  
  医学のあゆみ
  
  Volume: 233(10) Pages: 985-992
- Data Source
  KAKENHI-PROJECT-22510221
[Journal Article] BETファミリーとエピジェネティクな遺伝子発現制御機構2010
- Author(s)
  爪真美、木村-吉田千春、松尾勲
- Journal Title
  
  大阪府立母子保健総合医療センター雑誌
  
  Volume: 26 Pages: 10-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510221
[Journal Article] Possible involvement of SINEs in mammalian-specific brain formation.2008
- Author(s)
  T.Sasaki, H.Nishihara, M.Hirakawa, K.Fujimura, M.Tanaka, N.Kokubo, C.Kimura-Yoshida.I.Matsuo, K.Sumiyama, N.Saitou, T.Shimogori, and N.Okada.
- Journal Title
  
  Proceeding of the National Academy of Science of the United States of America. 105
  
  Pages: 4220-4225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18770214
[Journal Article] Cruciai roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes.2007
- Author(s)
  Kimura-Yoshida et al.
- Journal Title
  
  Proceeding of the National Academy of Sciences. 104
  
  Pages: 5919-5924
- Data Source
  KAKENHI-PROJECT-18770214
[Journal Article] Canonical Wnt signaling and its antagonist regulate anterior-posterior axis polarization by guiding cell migration in mouse visceral endoderm.2006
- Author(s)
  Kimura-Yoshida et al.
- Journal Title
  
  Developmental Cell 9
  
  Pages: 639-650
- Data Source
  KAKENHI-PROJECT-15770151
[Presentation] USP39 is essential for mammalian epithelial morphogenesis through upregulation of planar cell polarity components.2023
- Author(s)
  Chiharu Kmura-Yoshida, Kyoko Mochida, Shin-Ichiro Kanno, Isao Matsuo
- Organizer
  The 56th annual meeting of the Japanese Society of Developmental Biologists
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08291
[Presentation] 神経管閉鎖に働く特異な表皮細胞を誘導する新規因子の探索2023
- Author(s)
  木村‐吉田　千春, 持田　京子，菅野新一郎, 松尾　勲
- Organizer
  第126回日本小児科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08291
[Presentation] 神経管閉鎖に働く特異な表皮細胞を誘導する新規因子の探索2023
- Author(s)
  木村‐吉田　千春, 持田　京子，菅野新一郎, 松尾　勲
- Organizer
  第126回日本小児科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K06685
[Presentation] USP39 is essential for mammalian epithelial morphogenesis through upregulation of planar cell polarity components.2023
- Author(s)
  Chiharu Kmura-Yoshida, Kyoko Mochida, Shin-Ichiro Kanno, Isao Matsuo
- Organizer
  The 56th annual meeting of the Japanese Society of Developmental Biologists
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06685
[Presentation] 哺乳動物の上皮形成過程において、脱ユビキチン化酵素USP39因子は平面内極性(PCP経路）構成因子を活性化することで機能する2022
- Author(s)
  木村-吉田千春、持田京子、菅野新一郎、松尾勲
- Organizer
  第45回日本分子生物学会年会　（幕張メッセ）
- Data Source
  KAKENHI-PROJECT-19K06685
[Presentation] 哺乳動物の上皮形成過程において、脱ユビキチン化酵素USP39因子は平面内極性(PCP経路）構成因子を活性化することで機能する2022
- Author(s)
  木村-吉田千春、持田京子、菅野新一郎、松尾勲
- Organizer
  第45回日本分子生物学会年会　（幕張メッセ）
- Data Source
  KAKENHI-PROJECT-19K08291
[Presentation] マウス胚を用いた力学測定の実践2021
- Author(s)
  木村―吉田　千春、上田　陽子
- Organizer
  日本動物学会関東支部　第73回大会公開シンポジウム
- Data Source
  KAKENHI-PROJECT-19K06685
[Presentation] Intrauterine mechanical environment produced by smooth muscle contractions for early mouse morphogenesis2021
- Author(s)
  Isao Matsuo, Chiharu Kimura-Yoshida, Yoko Ueda
- Organizer
  第126回日本解剖学会総会・全国学術集会　第98回日本生理学会大会　合同大会細胞・組織のメカニクス
- Data Source
  KAKENHI-PROJECT-19K06685
[Presentation] BRD4はJAK/STAT標的遺伝子の転写活性化を介してマウス着床前胚におけるエピブラストの特異化に必要である2020
- Author(s)
  爪麻美、木村（吉田）千春、上田陽子、持田京子、松尾勲
- Organizer
  第43回日本分子生物学会年会 MBSJ2020
- Data Source
  KAKENHI-PROJECT-19K08291
[Presentation] Principles in the symmetry breaking in animal and plant development Embryo shape change from sphere to egg-cylinder mediated by intrauterine pressures is crucial for mouse primary axis formation.2020
- Author(s)
  Yoko Ueda, Chiharu Kimura-Yoshida, Kyoko Mochida, Mami Tsume, Yoshitaka Kameo, Taiji Adachi, Lefebvre Olivier, Ryuji Hiramatsu, Isao Matsuo
- Organizer
  第43回日本分子生物学会年会 MBSJ2020
- Data Source
  KAKENHI-PROJECT-19K06685
[Presentation] BRD4はJAK/STAT標的遺伝子の転写活性化を介してマウス着床前胚におけるエピブラストの特異化に必要である2020
- Author(s)
  爪麻美、木村－吉田千春、上田陽子、持田京子、松尾勲
- Organizer
  第43回日本分子生物学会年会 MBSJ2020
- Data Source
  KAKENHI-PROJECT-19K06685
[Presentation] Principles in the symmetry breaking in animal and plant development Embryo shape change from sphere to egg-cylinder mediated by intrauterine pressures is crucial for mouse primary axis formation.2020
- Author(s)
  Yoko Ueda, Chiharu Kimura-Yoshida, Kyoko Mochida, Mami Tsume, Yoshitaka Kameo, Taiji Adachi, Lefebvre Olivier, Ryuji Hiramatsu, Isao Matsuo
- Organizer
  第43回日本分子生物学会年会 MBSJ2020
- Data Source
  KAKENHI-PROJECT-19K08291
[Presentation] GRHL3タンパクの細胞質における局在が上皮細胞の分化過程から形態形成過程へと進行させる2019
- Author(s)
  Kimura-Yoshida C., Mochida K., Nakaya M., Mizutani T., Matsuo I.
- Organizer
  第52回日本発生生物学会大会　（大阪）
- Data Source
  KAKENHI-PROJECT-19K06685
[Presentation] マウス胚卵円筒形成に必要な子宮内の力学的環境2019
- Author(s)
  Ueda Y., Kimura-Yoshida C., Matsuo I.
- Organizer
  第52回日本発生生物学会大会　（大阪）
- Invited
- Data Source
  KAKENHI-PROJECT-19K06685
[Presentation] GRHL3タンパクの細胞質における局在が上皮細胞の分化過程から形態形成過程へと進行させる2019
- Author(s)
  Kimura-Yoshida C., Mochida K., Nakaya M., Mizutani T., Matsuo I.
- Organizer
  第52回日本発生生物学会大会　（大阪）
- Data Source
  KAKENHI-PROJECT-19K08291
[Presentation] マウス着床後胚におけるライヘルト膜の力学的機能の解析2018
- Author(s)
  上田陽子、吉田千春、爪麻美、持田京子、松尾勲
- Organizer
  第41回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-26291053
[Presentation] GRHL3 triggers epithelial morphogenesis from differentiation in uncommitted ectodermal progenitors during neural tube2018
- Author(s)
  Chiharu Kimura-Yoshida, Kyoko Mochida, Takeomi Mizutani, Isao Matsuo
- Organizer
  International Young Scientists Workshop on Neural Development & Stem Cells 2018
- Data Source
  KAKENHI-PROJECT-26291053
[Presentation] GRHL3因子は核から細胞質へ局在を変えることで、機能的で弾性率に富んだ上皮細胞を誘導する2018
- Author(s)
  木村-吉田千春、持田京子、中谷雅明、水谷武臣、松尾勲
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-26291053
[Presentation] マウス神経管閉鎖過程におけるGrainyhead-like 3の機能解析2017
- Author(s)
  松尾　勲、木村一吉田　千春
- Organizer
  Wnt研究会2017
- Data Source
  KAKENHI-PROJECT-26291053
[Presentation] Surface ectoderm specification of uncommitted ectodermal progenitors in the neural plate border is crucial for neural tube closure2017
- Author(s)
  Chiharu Kimura-Yoshida, Isao Matsuo
- Organizer
  50th Annual Meeting for the Japanese Society of Developmental Biologists
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291053
[Presentation] 神経管閉鎖時におけるGrainyhead-like 3遺伝子発現表皮細胞の機能解析2017
- Author(s)
  木村一吉田千春、持田京子、水谷武臣、松尾勲
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-26291053
[Presentation] Fate specification of neural plate border by canonical Wnt signaling and Grhl3 is crucial for mammalian neural tube closure.2016
- Author(s)
  Kimura-Yoshida C., Mochida K., Ellwanger K., Niehrs C., and Matsuo I.
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-25461720
[Presentation] Fate specification of neural plate border by canonical Wnt signaling and Grhl3 is crucial for mammalian neural tube closure2016
- Author(s)
  Chiharu Kimura-Yoshida, Kyoko Mochida, Kristina Ellwanger, Christof Niehrs, and Isao Matsuo
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-26291053
[Presentation] カルポニン３ノックアウトマウスの表現型解析2015
- Author(s)
  渋川幸直、山崎奈津子、大門江津子、木村－吉田千春、持田京子、松尾勲、和田芳直
- Organizer
  BMB2015　第38回日本分子生物学会年会　第88回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26291053
[Presentation] カルポニン３ノックアウトマウスの表現型解析2015
- Author(s)
  渋川幸直, 山崎奈津子, 大門江津子, 木村ー吉田千春, 持田京子, 松尾勲, 和田芳直
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25461720
[Presentation] 神経管閉鎖過程におけるカノニカルWnt経路とGrhl3 遺伝子を介した未分化前駆細胞から表皮への細胞運命決定機構2015
- Author(s)
  木村-吉田千春、持田京子、Kristina Ellwanger、Christof Niehrs、松尾勲
- Organizer
  BMB2015　第38回日本分子生物学会年会　第88回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26291053
[Presentation] 神経管閉鎖過程におけるカノニカルWnt経路とGrhl3遺伝子を介した未分化前駆細胞から表皮への細胞運命決定機構2015
- Author(s)
  木村-吉田千春、持田京子、Kristina Ellwanger、Christof Niehrs、松尾勲
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25461720
[Presentation] Canonical Wnt Signaling Specifies Neural- and Surface-ectoderm Cell Fates through Grainyhead-like Factors to Coordinate Mammalian Neurulation2013
- Author(s)
  Chiharu Kimura-Yoshida, Kyoko Mochida,Kristina Ellwanger, Christof Niehrs, Isao Matsuo
- Organizer
  The 61st NIBB conference in Mammalian Embryogenesis
- Place of Presentation
  愛知県岡崎市
- Data Source
  KAKENHI-PROJECT-25461720
[Presentation] Bipotential ectodermal stem cells, crucial boundaries between surface ectoderm and neural ectoderm, are specified in coordination with mammalian neural tube closure2013
- Author(s)
  Isao Matsuo, Kyoko Mochida, Kristina Ellwanger, Christof Niehrs, Chiharu Kimura-Yoshida
- Organizer
  2013 Exciting Biologies meeting, "Biology of Boundaries"
- Place of Presentation
  SavudrijaCroatia
- Data Source
  KAKENHI-PROJECT-25461720
[Presentation] The Role of External Mechanical Cues in the Establishment of the Anterior-posterior Axis in Early Mouse Embryos2013
- Author(s)
  Ryuji Hiramatsu, Chiharu Kimura-Yoshida, Isao Matsuo
- Organizer
  The 61st NIBB conference in Mammalian Embryogenesis
- Place of Presentation
  愛知県岡崎市
- Data Source
  KAKENHI-PROJECT-25461720
[Presentation] マウス胚発生過程におけるBETドメインタンパク質の役割2013
- Author(s)
  爪麻美、木村-吉田千春、松尾勲
- Organizer
  第86回日本生化学学会年会
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-25461720
[Presentation] 哺乳類胚発生メカニズム解明への力学的アプローチ2013
- Author(s)
  平松竜司、吉田千春、松尾勲
- Organizer
  第156回日本獣医学会
- Place of Presentation
  岐阜県
- Data Source
  KAKENHI-PROJECT-25461720
[Presentation] External mechanical cues establish the anterior-posterior axis polarity in early mouse development2013
- Author(s)
  Ryuji Hiramatsu, Toshiki Matsuoka, Chiharu Kimura-Yoshida, Sung-Woong Han, Kyoko Mochida, Taiji Adachi, Shuichi Takayama and Isao Matsuo
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-25461720
[Presentation] Dickkopf1, an antagonist for canonical Wnt signaling, regulates determination between neuroectoderm and surface ectoderm from ectodermal cell lineage.2012
- Author(s)
  Chiharu KIMURA-YOSHIDA, Isao MATSUO
- Organizer
  Mouse Moulecular Genetics
- Place of Presentation
  サンフランシスコ
- Data Source
  KAKENHI-PROJECT-22510221
[Presentation] Dickkopf1, an antagonist for canonical Wnt signaling, regulates determination between neuroectoderm and surface ectoderm from ectodermal cell lineage2012
- Author(s)
  Chiharu Kimura-Yoshida and Isao Matsuo
- Organizer
  Mouse Molecular Genetics Meeting
- Place of Presentation
  Asilomar Conference Grounds, Pacific Grove, CA, USA ポスター
- Year and Date
  2012-10-04
- Data Source
  KAKENHI-PROJECT-22510221
[Presentation] Dickkopf1, an antagonist for canonical Wnt signaling, regulates determination between neuroectoderm and surface ectoderm from ectodermal cell lineage2011
- Author(s)
  Chiharu Kimura-Yoshida and Isao Matsuo
- Organizer
  Stem Cell Biology
- Place of Presentation
  Cold Spring Harbor Laboratory, NY, USA, ポスター
- Data Source
  KAKENHI-PROJECT-22510221
[Presentation] Dickkopf1, an antagonist for canonical Wnt signaling regulates determination between neuroectoderm and surface ectoderm from ectodermal cell lineage2011
- Author(s)
  C.Kimura-Yoshida, I.Matsuo
- Organizer
  Stem cell Biology
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Data Source
  KAKENHI-PROJECT-22510221
[Presentation] WNT signaling regulates forebrain size by determining the border or cell fate between neuroectoderm and surface ectoderm2009
- Author(s)
  Chiharu Kimura-Yoshida
- Organizer
  Wnt 2009 meeting EMBO Workshop Wnt Signaling in Development and Disease
- Place of Presentation
  Arolla, Switzerland
- Year and Date
  2009-08-27
- Data Source
  KAKENHI-PROJECT-20017028
[Presentation] Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation ofanterior visceral endoderm-specific genes2008
- Author(s)
  木村-吉田千春, 等
- Organizer
  第40回日本発生生物学会、第59回合同大会目本細胞生物学会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2008-05-28
- Data Source
  KAKENHI-PROJECT-18770214

1. MATSUO Isao (10264285)

# of Collaborated Projects: 3 results

# of Collaborated Products: 32 results
2. Mochida Kyoko (00834417)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
3. Ueda Yoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 中川俊徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

yoshida chiharu 吉田 千春

YOSHIDA Chiharu 吉田 千春

Research Projects

Research Products

Co-Researchers

神経管閉鎖過程におけるカノニカルWnt経路に依存したGRHL3の核内局在と機能の制御機構Principal Investigator

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Identification of partner molecules that bind directly to GRHL3 factors during epidermal differentiation.

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Identification of partner molecules that bind directly to GRHL3 factors during epidermal differentiation.Principal Investigator

Principal Investigator

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Review Section

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Elucidation of the common etiology of spina bifida and cleft palate caused by epithelial fusion defects.

Principal Investigator

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Studies on roles of extracellular microenvironments in the body axis formation

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Fate specification coupled to neural tube closure between surface ectoderm and neural ectoderm.Principal Investigator

Principal Investigator

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Comprehensive analysis of the ectoderm differentiation using the system imagingPrincipal Investigator

Principal Investigator

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比較ゲノム解析による軸決定進化プロセスの解明

Principal Investigator

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Review Section

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器官形成過程におけるWnt関連因子の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

マウス胚の前後軸決定機構におけるWntシグナルの役割Principal Investigator

Principal Investigator

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Research Institution

[Book] 実験モデルマウスを用いた二分脊椎発症のメカニズムの解明2015

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[Book] ヘパラン硫酸鎖を介したFGF シグナルの局所的な受容機構, 細胞工学312012

Author(s)

Data Source

[Book] FGFシグナル制御の新たな制御機構-新規な活性調節分子の発見と関連疾患治療の最先端「基礎の基礎」, 細胞工学312012

Author(s)

Data Source

[Book] Wnt シグナルとマウス前後軸決定~Wnt 拮抗因子Dickkopf1 遺伝子に着目して~, 医学のあゆみ2010

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Publisher

Data Source

[Book] BET ファミリーとエピジェネティクな遺伝子発現制御機構2010

yoshida chiharu 吉田千春

YOSHIDA Chiharu 吉田千春