Osawa Masanori 大澤匡範

… Alternative Names

OSAWA Masanori 大澤匡範

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Researcher Number	60361606
Other IDs
Affiliation (Current)	2025: 慶應義塾大学, 薬学部(芝共立), 教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 慶應義塾大学, 薬学部(芝共立), 教授 2013 – 2014: 東京大学, 薬学研究科(研究院), 講師 2013: 東京大学, 大学院薬学系研究科, 講師 2012: 東京大学, 薬学研究科(研究院), 助教 2007 – 2011: The University of Tokyo, 大学院・薬学系研究科, 助教 2006: 東京大学, 大学院薬学系研究科, 助手 2004 – 2005: 東京大学, 大学院・薬学系研究科, 助手
Review Section/Research Field	Principal Investigator Physical pharmacy / Biological Sciences / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Biological Sciences / Complex systems / Science and Engineering Except Principal Investigator Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Basic Section 53010:Gastroenterology-related / Physical pharmacy / Complex systems
Keywords	Principal Investigator NMR / 構造生物学 / 電位依存性イオンチャネル / 相互作用解析 / 電位センサードメイン / 相互作用 / 膜タンパク質 / ITC / 電位依存性プロトンチャネル / アラキドン酸 … More / 多価不飽和脂肪酸 / 構造変化 / gating modifier toxin / 複合体構造 / 分子認識 / 不均一系 / 超分子 / ポリA結合蛋白質(PABP) / 翻訳終結因子eRF3 / 競合 / 拮抗 / 機能発現メカニズム / 動作メカニズム / 機能構造 / 結合親和性 / 14-3-3タンパク質 / リン酸化シグナル経路 / FoxO3 / 14-3-3 / リン酸化シグナル / 電位依存性H+チャネル / interaction / voltage sensing domain / Gating Modifier Toxin / VGIC / 創薬 / 電気生理学 / 電位センサー / ナノディスク / 脂質 / 脂質二重膜 / リポクオリティ / Gタンパク質 / GIRK / 内向き整流性K+チャネル / rHDL / 膜電位依存性 / 電位依存性K+チャネル / SS-locking / ポアドメイン / VSOP / KcsA / 構造揺らぎ / イオンゲート / イオンチャネル / 分子認識様式 / 安定同位体標識 / 膜蛋白質 / mRNA分解酵素 / mRNA分解 / ポリA結合タンパク質 / 立体構造解析 / mRNA分解制御 / ポリA結合蛋白質(PABP … More Except Principal Investigator B型肝炎ウイルス / NMR / タンパク質―タンパク質相互作用 / 侵入阻害剤 / 胆汁酸誘導体 / ウイルス侵入機構 / 感染制御 / 侵入阻害 / 侵入機構 / in silicoスクリーニング / 等温滴定型カロリメトリー / X線結晶構造解析 / HBV / ナノディスク / タンパク質－タンパク質相互作用 / タンパク質ータンパク質相互作用 / 無細胞タンパク質合成 / NTCP / キャプシド / 無細胞合成 / 構造平衡 / 転移交差飽和法 / 構造生物学 / 過渡的複合体 / 相互作用 / 膜タンパク質 / 核磁気共鳴法 Less

Mechanism of antagonistic action for intermolecular interactions between etiological biopolymers, and novel strategies for drug discoveryPrincipal Investigator
- Principal Investigator
  
  大澤匡範
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Keio University
Elucidation of the mechanism of hepatitis B virus entry and control of infection by entry inhibitors
- Principal Investigator
  
  伊藤清顕
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Aichi Medical University
Structural mechanism of voltage-gated ion channels based on the functional structures and their transitionsPrincipal Investigator
- Principal Investigator
  
  Osawa Masanori
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Keio University
Structural basis for the hepatocyte specific entry and replication mechanisms of hapatitis B virus and structural based drug discovery
- Principal Investigator
  
  Yokogawa Mariko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Keio University
14-3-3タンパク質によるリン酸化シグナル経路の熱力学的・構造生物学的基盤Principal Investigator
- Principal Investigator
  
  大澤匡範
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Keio University
Structural analysis of hepatocyte specific entry and replication mechanism of hepatitis B virus
- Principal Investigator
  
  Yokogawa Mariko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Keio University
リポクオリティと膜蛋白質の相互作用のＮＭＲ解析法の開発Principal Investigator
- Principal Investigator
  
  大澤匡範
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Keio University
抗がん剤トランスポーターの構造と機能発現機構の解明
- Principal Investigator
  
  秋元まどか
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Keio University
Functional regulation of voltage-gated ion channels targeting the voltage sensorPrincipal Investigator
- Principal Investigator
  
  Osawa Masanori
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Keio University
リポクオリティと膜蛋白質の相互作用のNMR解析法の開発Principal Investigator
- Principal Investigator
  
  大澤匡範
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
三量体G蛋白質によるイオンチャネル活性化シグナリングの構造基盤Principal Investigator
- Principal Investigator
  
  大澤匡範
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Voltage-dependent structural changes and functinal mechanism of voltage-dependent ion channelsPrincipal Investigator
- Principal Investigator
  
  OSAWA Masanori
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo
ＮＭＲによる電位依存性イオンチャネルの動的構造と機能発現機構の解明Principal Investigator
- Principal Investigator
  
  大澤匡範
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Structural analyses of the metastable ligand-receptor interactions
- Principal Investigator
  
  SHIMADA Ichio
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
Motional linkage between voltage sensor and ion gate in voltage-dependent ion channelsPrincipal Investigator
- Principal Investigator
  
  OSAWA Masanori
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo
不均一系超分子における分子認識機構を解明するNMR戦略の開発Principal Investigator
- Principal Investigator
  
  大澤匡範
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Development of an NMR strategy for the structural analysis of themolecular recognition in the membrane protein complex in lipidbilayersPrincipal Investigator
- Principal Investigator
  
  OSAWA Masanori
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo
不均一系超分子における分子認識機構を解明するNMR戦略の開発Principal Investigator
- Principal Investigator
  
  大澤匡範
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
翻訳終結と共役したmRNA分解制御機構の構造生物学的解明Principal Investigator
- Principal Investigator
  
  大澤匡範
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
不均一系超分子における分子認識機構を解明するNMR戦略の開発Principal Investigator
- Principal Investigator
  
  大澤匡範
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
翻訳終結因子eRF3のmRNA分解制御機構の構造生物学的解析Principal Investigator
- Principal Investigator
  
  大澤匡範
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo

[Book] 脂質クオリティ2018
- Author(s)
  大澤匡範、岡村康司、有田　誠、他
- Total Pages
  220
- Publisher
  羊土社
- ISBN
  9784758103718
- Data Source
  KAKENHI-PUBLICLY-18H04679
[Book] 脂質クオリティ2018
- Author(s)
  大澤匡範、岡村康司、有田　誠、他
- Total Pages
  220
- Publisher
  羊土社
- ISBN
  9784758103718
- Data Source
  KAKENHI-PROJECT-17H03978
[Book] Large Protein Complexes Revealed by Solution-State NMR: G Proteins and G Protein-Activated Inwardly Rectifying　Potassium Ion Channel2013
- Author(s)
  Osawa M., Mase Y., Yokogawa M., Takeuchi K. and Shimada I.
- Total Pages
  32
- Publisher
  Royal Society of Chemistry
- Data Source
  KAKENHI-PUBLICLY-25121707
[Book] Large Protein Complexes Revealed by Solution-State NMR: G Proteins and G Protein-Activated Inwardly Rectifying Potassium Ion Channel2013
- Author(s)
  Osawa M., Mase Y., Yokogawa M., Takeuchi K. and Shimada I.
- Total Pages
  32
- Publisher
  Royal Society of Chemistry
- Data Source
  KAKENHI-PROJECT-24590048
[Book] 【試料分析講座】「蛋白質の分析」, 分析化学会2012
- Author(s)
  大澤匡範、今井駿輔、嶋田一夫.
- Total Pages
  34
- Publisher
  丸善
- Data Source
  KAKENHI-PROJECT-24590048
[Book] 【試料分析講座】「蛋白質の分析」, 分析化学会2012
- Author(s)
  大澤匡範、今井駿輔、嶋田一夫.
- Total Pages
  34
- Publisher
  丸善
- Data Source
  KAKENHI-PUBLICLY-23107708
[Book] 実験医学別冊「生命科学のための機器分析実験ハンドブック」2007
- Author(s)
  大澤匡範
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-19590037
[Book] 実験医学別冊「生命科学のための機器分析実験ハンドブック」2007
- Author(s)
  大澤匡範
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-18054006
[Book] 「等温滴定型カロリメトリー(ITC)-熱量測定による相互作用の定量的解析-」実験医学別冊「生命科学のための機器分析実験ハンドブック2007
- Author(s)
  大澤匡範、嶋田一夫
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-19590037
[Journal Article] DLiP-PPI library: An integrated chemical database of small-to-medium-sized molecules targeting protein?protein interactions2023
- Author(s)
  Ikeda Kazuyoshi、Maezawa Yuta、Yonezawa Tomoki、Shimizu Yugo、Tashiro Toshiyuki、Kanai Satoru、Sugaya Nobuyoshi、Masuda Yoshiaki、Inoue Naoko、Niimi Tatsuya、Masuya Keiichi、Mizuguchi Kenji、Furuya Toshio、Osawa Masanori
- Journal Title
  
  Frontiers in Chemistry
  
  Volume: 10 Pages: 1-9
- DOI
  10.3389/fchem.2022.1090643
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15258, KAKENHI-PROJECT-21H02618, KAKENHI-PROJECT-23K24323
[Journal Article] TDP‐43 N‐terminal domain dimerisation or spatial separation by RNA binding decreases its propensity to aggregate2023
- Author(s)
  Miura Motoki、Sakaue Fumika、Matsuno Hirokazu、Morita Kento、Yoshida Akiko、Hara Rintaro Iwata、Nishimura Ren、Nishida Yurika、Yokogawa Mariko、Osawa Masanori、Yokota Takanori
- Journal Title
  
  FEBS Letters
  
  Volume: 597 Issue: 12 Pages: 1667-1676
- DOI
  10.1002/1873-3468.14635
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06494, KAKENHI-PROJECT-21H02618, KAKENHI-PROJECT-23K24323
[Journal Article] Applying deep learning to iterative screening of medium-sized molecules for protein-protein interaction-targeted drug discovery2023
- Author(s)
  Yugo Shimizu、Tomoki Yonezawa、Yu Bao、Junichi Sakamoto、Mariko Yokogawa、Toshio Furuya、Masanori Osawa、Kazuyoshi Ikeda
- Journal Title
  
  Chemical Communications
  
  Volume: 59 Issue: 44 Pages: 6722-6725
- DOI
  10.1039/d3cc01283b
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15258, KAKENHI-PROJECT-21K06494, KAKENHI-PROJECT-21H02618, KAKENHI-PROJECT-23K24323
[Journal Article] AI-driven molecular generation of not-patented pharmaceutical compounds using world open patent data2023
- Author(s)
  Shimizu Yugo、Ohta Masateru、Ishida Shoichi、Terayama Kei、Osawa Masanori、Honma Teruki、Ikeda Kazuyoshi
- Journal Title
  
  Journal of Cheminformatics
  
  Volume: 15 Issue: 1
- DOI
  10.1186/s13321-023-00791-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02618, KAKENHI-PROJECT-23K24323
[Journal Article] Paip2A inhibits translation by competitively binding to the RNA recognition motifs of PABPC1 and promoting its dissociation from the poly(A) tail2022
- Author(s)
  Takeru Sagae, Mariko Yokogawa, Ryoichi Sawazaki, Yuichiro Ishii, Nao Hosoda, Shin-Ichi Hoshino, Shunsuke Imai, Ichio Shimada, Masanori Osawa
- Journal Title
  
  J Biol Chem
  
  Volume: － Issue: 5 Pages: 101844-101844
- DOI
  10.1016/j.jbc.2022.101844
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06494, KAKENHI-PROJECT-21H02618, KAKENHI-PROJECT-23K24323
[Journal Article] Mechanism of hERG inhibition by gating-modifier toxin, APETx1, deduced by functional characterization2021
- Author(s)
  Matsumura Kazuki、Shimomura Takushi、Kubo Yoshihiro、Oka Takayuki、Kobayashi Naohiro、Imai Shunsuke、Yanase Naomi、Akimoto Madoka、Fukuda Masahiro、Yokogawa Mariko、Ikeda Kazuyoshi、Kurita Jun-ichi、Nishimura Yoshifumi、Shimada Ichio、Osawa Masanori
- Journal Title
  
  BMC Molecular and Cell Biology
  
  Volume: 22 Issue: 1 Pages: 1-16
- DOI
  10.1186/s12860-020-00337-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07284, KAKENHI-PUBLICLY-19H04973, KAKENHI-PUBLICLY-20H05449, KAKENHI-PROJECT-20H03424, KAKENHI-PROJECT-18K06152, KAKENHI-PROJECT-18K06606, KAKENHI-PROJECT-17H06097
[Journal Article] Peptide Toxins Targeting KV Channels2021
- Author(s)
  Matsumura Kazuki、Yokogawa Mariko、Osawa Masanori
- Journal Title
  
  Handb. Exp. Pharmacol.
  
  Volume: 267 Pages: 481-505
- DOI
  10.1007/164_2021_500
- ISBN
  9783030840518, 9783030840525
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02618, KAKENHI-PROJECT-21K06494
[Journal Article] Identification of novel inhibitors of Keap1/Nrf2 by a promising method combining protein-protein interaction-oriented library and machine learning2021
- Author(s)
  Shimizu Yugo、Yonezawa Tomoki、Sakamoto Junichi、Furuya Toshio、Osawa Masanori、Ikeda Kazuyoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 7420-7420
- DOI
  10.1038/s41598-021-86616-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02618
[Journal Article] Comprehensive Approach of 19F Nuclear Magnetic Resonance, Enzymatic, and In Silico Methods for Site-Specific Hit Selection and Validation of Fragment Molecules that Inhibit Methionine γ-Lyase Activity2021
- Author(s)
  Ikeda Kazuyoshi、Kezuka Yuichiro、Nonaka Takamasa、Yonezawa Tomoki、Osawa Masanori、Katoh Etsuko
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 64 Issue: 19 Pages: 14299-14310
- DOI
  10.1021/acs.jmedchem.1c00766
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02618
[Journal Article] GZD824 Inhibits GCN2 and Sensitizes Cancer Cells to Amino Acid Starvation Stress2020
- Author(s)
  Kato Yu、Kunimasa Kazuhiro、Takahashi Mizuki、Harada Ayaka、Nagasawa Ikuko、Osawa Masanori、Sugimoto Yoshikazu、Tomida Akihiro
- Journal Title
  
  Molecular Pharmacology
  
  Volume: 98 Issue: 6 Pages: 669-676
- DOI
  10.1124/molpharm.120.000070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16339, KAKENHI-PUBLICLY-19H04973, KAKENHI-PROJECT-19H03526, KAKENHI-PROJECT-18K07302, KAKENHI-PROJECT-18K07309, KAKENHI-PROJECT-18K19486
[Journal Article] Conformational equilibrium shift underlies altered K+ channel gating as revealed by NMR2020
- Author(s)
  Iwahashi Yuta、Toyama Yuki、Imai Shunsuke、Itoh Hiroaki、Osawa Masanori、Inoue Masayuki、Shimada Ichio
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 5168-5168
- DOI
  10.1038/s41467-020-19005-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H04973, KAKENHI-PROJECT-17H06110, KAKENHI-PROJECT-19K15704, KAKENHI-PROJECT-17H06097
[Journal Article] Structural mechanism underlying G protein family-specific regulation of G protein-gated inwardly rectifying potassium channel2019
- Author(s)
  Kano Hanaho、Toyama Yuki、Imai Shunsuke、Iwahashi Yuta、Mase Yoko、Yokogawa Mariko、Osawa Masanori、Shimada Ichio
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 1-13
- DOI
  10.1038/s41467-019-10038-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06606, KAKENHI-PUBLICLY-18H04679, KAKENHI-PUBLICLY-19H04973, KAKENHI-PROJECT-17H03978, KAKENHI-PROJECT-17H06097
[Journal Article] Nanodiscs for Structural Biology in a Membranous Environment2019
- Author(s)
  Yokogawa M., Fukuda M., Osawa M.
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 67 Issue: 4 Pages: 321-326
- DOI
  10.1248/cpb.c18-00941
- NAID
  130007621752
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2019-04-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06606, KAKENHI-PUBLICLY-18H04679, KAKENHI-PROJECT-17H03978
[Journal Article] Structural basis for the ethanol action on G-protein?activated inwardly rectifying potassium channel 1 revealed by NMR spectroscopy2018
- Author(s)
  Toyama Yuki、Kano Hanaho、Mase Yoko、Yokogawa Mariko、Osawa Masanori、Shimada Ichio
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 115 Issue: 15 Pages: 3858-3863
- DOI
  10.1073/pnas.1722257115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-16H01368, KAKENHI-PROJECT-17H03978, KAKENHI-PROJECT-16K18866, KAKENHI-PROJECT-18J13147
[Journal Article] Characterization of the multimeric structure of poly(A)-binding protein on a poly(A) tail2018
- Author(s)
  Sawazaki Ryoichi、Imai Shunsuke、Yokogawa Mariko、Hosoda Nao、Hoshino Shin-ichi、Mio Muneyo、Mio Kazuhiro、Shimada Ichio、Osawa Masanori
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 1455-1455
- DOI
  10.1038/s41598-018-19659-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-16H01368, KAKENHI-PUBLICLY-17H05539, KAKENHI-PROJECT-17H03978, KAKENHI-PROJECT-16K18866, KAKENHI-PROJECT-17H03635
[Journal Article] Functional roles of Mg2+ binding sites in ion-dependent gating of a Mg2+ channel, MgtE, revealed by solution NMR2018
- Author(s)
  Maruyama Tatsuro、Imai Shunsuke、Kusakizako Tsukasa、Hattori Motoyuki、Ishitani Ryuichiro、Nureki Osamu、Ito Koichi、Maturana Andr?s D、Shimada Ichio、Osawa Masanori
- Journal Title
  
  eLife
  
  Volume: 7
- DOI
  10.7554/elife.31596
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-18H04679, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-17H03978, KAKENHI-PROJECT-16H06294
[Journal Article] Dynamic regulation of GDP binding to G proteins revealed by magnetic field-dependent NMR relaxation analyses2017
- Author(s)
  Yuki Toyama, Hanaho Kano, Yoko Mase, Mariko Yokogawa, Masanori Osawa, Ichio Shimada
- Journal Title
  
  Nat. Commun.
  
  Volume: 8 Issue: 1 Pages: 14523-14523
- DOI
  10.1038/ncomms14523
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01368, KAKENHI-PROJECT-16K18866
[Journal Article] ATP-dependent modulation of MgtE in Mg2+ homeostasis2017
- Author(s)
  Tomita Atsuhiro、Zhang Mingfeng、Jin Fei、Zhuang Wenhui、Takeda Hironori、Maruyama Tatsuro、Osawa Masanori、Hashimoto Ken-ichi、Kawasaki Hisashi、Ito Koichi、Dohmae Naoshi、Ishitani Ryuichiro、Shimada Ichio、Yan Zhiqiang、Hattori Motoyuki、Nureki Osamu
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 148-148
- DOI
  10.1038/s41467-017-00082-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-16H01368, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-17H03978, KAKENHI-PROJECT-16H06294
[Journal Article] Nuclear Magnetic Resonance Approaches for Characterizing Protein-Protein Interactions2017
- Author(s)
  Toyama Yuki、Mase Yoko、Kano Hanaho、Yokogawa Mariko、Osawa Masanori、Shimada Ichio
- Journal Title
  
  Methods in Molecular Biology (invited review)
  
  Volume: 1684 Pages: 115-128
- DOI
  10.1007/978-1-4939-7362-0_10
- ISBN
  9781493973613, 9781493973620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-16H01368, KAKENHI-PROJECT-17H03978, KAKENHI-PROJECT-16K18866, KAKENHI-PROJECT-18K06606
[Journal Article] Disulfide mapping the voltage-sensing mechanism of a voltage-dependent potassium channel2016
- Author(s)
  Tomohiro Nozaki, Shin-ichiro Ozawa, Hitomi Harada, Tomomi Kimura, Masanori Osawa, Ichio Shimada
- Journal Title
  
  Sci. Rep.
  
  Volume: 6 Issue: 1 Pages: 37303-37303
- DOI
  10.1038/srep37303
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Journal Article] Calmodulin and STIM proteins: Two major calcium sensors in the cytoplasm and endoplasmic reticulum2015
- Author(s)
  Marshall CB, Nishikawa T, Osawa M, Stathopulos PB, Ikura M
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 印刷中 Issue: 1 Pages: 5-21
- DOI
  10.1016/j.bbrc.2015.01.106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590048, KAKENHI-PUBLICLY-25121707
[Journal Article] Structural basis for the binding of the membrane-proximal C-terminal region of chemokine receptor CCR2 with the cytosolic regulator FROUNT2014
- Author(s)
  Esaki K, Yoshinaga S, Tsuji T, Toda E, Terashima Y, Saitoh T, Kohda D, Kohno T, Osawa M, Ueda T, Shimada I, Matsushima K, Terasawa H
- Journal Title
  
  FEBS J
  
  Volume: 281 Issue: 24 Pages: 552-566
- DOI
  10.1111/febs.13096
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-21121001, KAKENHI-PROJECT-24590048, KAKENHI-PUBLICLY-25121707, KAKENHI-PROJECT-26670326, KAKENHI-PROJECT-26860317
[Journal Article] Functional dynamics of cell surface membrane proteins2014
- Author(s)
  Nishida N, Osawa M, Takeuchi K, Imai S, Stampoulis P, Kofuku Y, Ueda T, Shimada I
- Journal Title
  
  J Magn Reson
  
  Volume: 241 Pages: 86-96
- DOI
  10.1016/j.jmr.2013.11.007
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-21121001, KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-24590048, KAKENHI-PROJECT-24770090, KAKENHI-PUBLICLY-25121707, KAKENHI-PUBLICLY-25121708, KAKENHI-PUBLICLY-25121743, KAKENHI-PROJECT-25460033, KAKENHI-PLANNED-26119005
[Journal Article] Cross-saturation and transferred cross-saturation experiments2014
- Author(s)
  Ueda T, Takeuchi K, Nishida N, Stampoulis P, Kofuku Y, Osawa M, Shimada I
- Journal Title
  
  Q Rev Biophys
  
  Volume: 47 Issue: 2 Pages: 143-187
- DOI
  10.1017/s0033583514000043
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-21121001, KAKENHI-PROJECT-24590048, KAKENHI-PROJECT-24770090, KAKENHI-PUBLICLY-25121707, KAKENHI-PUBLICLY-25121708, KAKENHI-PROJECT-25460033, KAKENHI-PLANNED-26119005
[Journal Article] Backbone resonance assignments for G protein αi3 subunit in the GDP-bound state.2014
- Author(s)
  Mase Y., Yokogawa M., Osawa M., and Shimada I.
- Journal Title
  
  Biomol. NMR Assign.
  
  Volume: 8 Issue: 2 Pages: 237-241
- DOI
  10.1007/s12104-013-9491-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590048, KAKENHI-PUBLICLY-25121707
[Journal Article] Backbone resonance assignments for the cytoplasmic region of the Mg(2+) transporter MgtE in the Mg (2+)-unbound state2013
- Author(s)
  Maruyama T, Imai S, Osawa M, Hattori M, Ishitani R, Nureki O, Shimada I.
- Journal Title
  
  Biomol NMR Assign
  
  Volume: 7 Issue: 1 Pages: 93-96
- DOI
  10.1007/s12104-012-9385-y
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21121001, KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-21590040, KAKENHI-PROJECT-22687007, KAKENHI-PUBLICLY-23107708, KAKENHI-PROJECT-24590048, KAKENHI-PUBLICLY-25121707
[Journal Article] Backbone resonance assignments for G protein α(i3) subunit in the GDP-bound state2013
- Author(s)
  Mase Y, Yokogawa M, Osawa M, Shimada I.
- Journal Title
  
  Biomol NMR Assign
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121002
[Journal Article] Solution NMR study on functional mechanism of membrane proteins2013
- Author(s)
  Osawa M., Imai S., Takeuchi K, and Shimada I.
- Journal Title
  
  Seibutsubutsuri
  
  Volume: 53 Pages: 236-241
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25121707
[Journal Article] Solution NMR study on functional mechanism of membrane proteins2013
- Author(s)
  Osawa M., Imai S., Takeuchi K, and Shimada I.
- Journal Title
  
  Seibutsubutsuri
  
  Volume: 53 Pages: 236-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590048
[Journal Article] Backbone resonance assignments for the cytoplasmic region of the Mg^<2+> transporter MgtE in the Mg^<2+-> unboundstate2012
- Author(s)
  Maruyama T, Imai S, Osawa M, Hattori M, Ishitani R, Nureki O, Shimada I.
- Journal Title
  
  Biomol NMR Assign
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590040
[Journal Article] Spatial distribution of cytoplasmic domains of the Mg(2+)-transporter MgtE, in a solution lacking Mg(2+), revealed by paramagnetic relaxation enhancement2012
- Author(s)
  Imai S, Maruyama T, Osawa M, Hattori M, Ishitani R, Nureki O, Shimada I.
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1824 Issue: 10 Pages: 1129-1135
- DOI
  10.1016/j.bbapap.2012.06.008
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-22687007, KAKENHI-PROJECT-24590048, KAKENHI-PUBLICLY-23107708, KAKENHI-ORGANIZER-21121001
[Journal Article] Structural basis for the modulation of the gating property of G protein-gated inwardly rectifying potassium ion channel (GIRK)by the i/o-family G protein α subunit (Gdi_<i/o>)2012
- Author(s)
  間瀬瑶子
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 287 Issue: 23 Pages: 19537-19549
- DOI
  10.1074/jbc.m112.353888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J08566, KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-24590048, KAKENHI-PUBLICLY-23107708, KAKENHI-ORGANIZER-21121001
[Journal Article] Backbone resonance assignments for Gproteinτ(i3) subunit in the GTP-boundstate2012
- Author(s)
  Mase Y, Yokogawa M, Osawa M, Shimada I.
- Journal Title
  
  Biomol NMR Assign
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590040
[Journal Article] Functional equilibrium of the KcsA structure revealed by NMR2012
- Author(s)
  Imai S, Osawa M, Mita K, Toyonaga S, Machiyama A, Ueda T, Takeuchi K, Oiki S, Shimada I.
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Issue: 47 Pages: 39634-39641
- DOI
  10.1074/jbc.m112.401265
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-23370067, KAKENHI-PROJECT-23790064, KAKENHI-PROJECT-24590048, KAKENHI-PROJECT-24659096, KAKENHI-PROJECT-24659097, KAKENHI-PUBLICLY-23107708, KAKENHI-PUBLICLY-23107735, KAKENHI-ORGANIZER-21121001
[Journal Article] Backbone resonance assignments for G protein α(i3) subunit in the GTP-bound state2012
- Author(s)
  Mase Y, Yokogawa M, Osawa M, Shimada I.
- Journal Title
  
  Biomol NMR Assign
  
  Volume: 6 Issue: 2 Pages: 217-220
- DOI
  10.1007/s12104-012-9361-6
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-21590040, KAKENHI-PUBLICLY-23107708, KAKENHI-PROJECT-24590048, KAKENHI-ORGANIZER-21121001
[Journal Article] Functional dynamics of proteins revealed by solution NMR2012
- Author(s)
  Osawa M, Takeuchi K, Ueda T, Nishida N, Shimada I.
- Journal Title
  
  Curr Opin Struct Biol
  
  Volume: 22 Issue: 5 Pages: 660-669
- DOI
  10.1016/j.sbi.2012.08.007
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-23790064, KAKENHI-PROJECT-24590048, KAKENHI-PROJECT-24770090, KAKENHI-PUBLICLY-23107708, KAKENHI-PUBLICLY-23107735, KAKENHI-ORGANIZER-21121001
[Journal Article] Biological role of the two overlapping poly(A)-binding protein interacting motifs 2 (PAM2) of eukaryotic releasing factor eRF3 in mRNA decay.2012
- Author(s)
  Osawa M, Hosoda N, Nakanishi T, Uchida N, Kimura T, Imai S, Machiyama A, Katada T, Hoshino S, Shimada I.
- Journal Title
  
  RNA
  
  Volume: 18 Issue: 11 Pages: 1957-1967
- DOI
  10.1261/rna.035311.112
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-23659045, KAKENHI-PUBLICLY-24113513, KAKENHI-PROJECT-24570050, KAKENHI-PROJECT-24590048, KAKENHI-PROJECT-24657081, KAKENHI-PLANNED-20112005, KAKENHI-PUBLICLY-23107708, KAKENHI-ORGANIZER-21121001
[Journal Article] NMR Analyses of the GβγBinding and Conformational Rearrangements of the Cytoplasmic Pore of G Protein-activated Inwardly Rectifying Potassium Channel 1(GIRK1)2011
- Author(s)
  Yokogawa M, Osawa M, Takeuchi K, MaseY, Shimada I.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Issue: 3 Pages: 2215-2223
- DOI
  10.1074/jbc.m110.160754
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590040
[Journal Article] Structure determination of a protein assembly by amino acid selective cross-saturation2011
- Author(s)
  Eiji Kanamori, Shunsuke Igarashi, Masanori Osawa, Yoshifumi Fukunishi, Ichio Shimada, Haruki Nakamura
- Journal Title
  
  Proteins
  
  Volume: 79 Pages: 179-190
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121002
[Journal Article] Structure determination of a protein assembly by amino acid selective cross-saturation2011
- Author(s)
  Kanamori E., Igarashi S., Osawa M., Fukunishi Y., Shimada I., Nakamura H.
- Journal Title
  
  Proteins
  
  Volume: 79 Issue: 1 Pages: 179-190
- DOI
  10.1002/prot.22871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590040
[Journal Article] Quantitative characterization of the Tob interactions provides the thermodynamic basis on the translation termination-coupled deadenylase regulation2010
- Author(s)
  Lin Ruan, Masanori Osawa, Nao Hosoda, Shunsuke Imai, Asako Machiyama, Toshiaki Katada, Shin-ichi Hoshino, Ichio Shimada
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 285 Pages: 27624-27631
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121002
[Journal Article] NMR analyses of the interaction between CCR5 and its ligand using functional reconstitution of CCR5 in lipid bilayers2010
- Author(s)
  Yoshiura C, Kofuku Y, Ueda T, Mase Y, Yokogawa M, Osawa M, Terashima Y, Matsushima K, Shimada I
- Journal Title
  
  J Am Chem Soc.
  
  Volume: 132(19) Issue: 19 Pages: 6768-77
- DOI
  10.1021/ja100830f
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-21590040
[Journal Article] NMR analyses of the interaction between CCR5 and its ligand using functional reconstitution of CCR5 in lipid bilayers2010
- Author(s)
  Chie Yoshiura, Yutaka Kofuku, Takumi Ueda, Yoko Mase, Mariko Yokogawa, Masanori Osawa, Yuya Terashima, Kouji Matsushima, Ichio Shimada
- Journal Title
  
  J.Am.Chem.Soc.
  
  Volume: 132 Pages: 6768-6777
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121002
[Journal Article] Quantitative characterization of Tob interactions provides the thermodynamic basis for translation termination-coupled deadenylase regulation2010
- Author(s)
  Ruan L., Osawa M., Hosoda N., Imai S., Machiyama A., Katada T., Hoshino S., Shimada I.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285(36) Issue: 36 Pages: 27624-27631
- DOI
  10.1074/jbc.m110.138867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590040
[Journal Article] Structural basis underlying the dual gate properties of KcsA2010
- Author(s)
  Imai S, Osawa M, Takeuchi K, Shimada I
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 107(14) Issue: 14 Pages: 6216-21
- DOI
  10.1073/pnas.0911270107
- Data Source
  KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-21590040
[Journal Article] Backbone resonance assignments for the ligand binding subunit of the histidine permeasecomplex(HisJ) from Escherichia coli, under histidine-bound and unbound states2010
- Author(s)
  Igarashi S., Osawa M., Ozawa S., Shimada I.
- Journal Title
  
  Biomol. NMR Assign
  
  Volume: 4(1) Issue: 1 Pages: 17-20
- DOI
  10.1007/s12104-009-9200-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590040
[Journal Article] Backbone resonance assignments for the ligand binding subunit of the histidine permease complex (HisJ) from Escherichia coli, under histidine-bound and unbound states.2010
- Author(s)
  Igarashi S, Osawa M, Ozawa S, Shimada I.
- Journal Title
  
  Biomol NMR Assign.
  
  Volume: 4 Pages: 7-20
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121002
[Journal Article] Structural basis underlying the dual gate properties of KcsA2010
- Author(s)
  Shunsuke Imai, Masanori Osawa, Koh Takeuchi, Ichio Shimada
- Journal Title
  
  Proc.Natl.Acad.Sci.USA.
  
  Volume: 107 Pages: 6216-6221
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121002
[Journal Article] Evidence for the direct interaction of spermine with inwardly rectifying potassium channel2009
- Author(s)
  Masanori Osawa, et al
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 284 Pages: 26117-126
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121002
[Journal Article] Evidence for the direct interaction of spermine with the inwardly rectifying potassium channel2009
- Author(s)
  Osawa M., Yokogawa M., Muramatsu T., Kimura T., Mase Y., Shimada I.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 284(38) Issue: 38 Pages: 26117-26126
- DOI
  10.1074/jbc.m109.029355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590040
[Journal Article] Evidence for the direct interaction of spermine with the inwardly rectifying potassium channel.2009
- Author(s)
  Osawa M
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 26117-26126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590040
[Journal Article] Cross-saturation and transferred cross-saturation experiments2009
- Author(s)
  Shimada I., Ueda T., Matsumoto M., Sakakura M., Osawa M., Takeuchi K., Nishida N., Takahashi H.
- Journal Title
  
  Prog. Nuc. Magn. Reson. Spect
  
  Volume: 54 Issue: 2 Pages: 123-140
- DOI
  10.1016/j.pnmrs.2008.07.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590040
[Journal Article] Backbone resonance assignments for the cytoplasmic regions of Gprotein-activated inwardly rectifying potassium channel 1(GIRK1)2009
- Author(s)
  Yokogawa M., Muramatsu T., Takeuchi K., Osawa M., Shimada I.
- Journal Title
  
  Biomol. NMR Assign
  
  Volume: 3(1) Issue: 1 Pages: 125-128
- DOI
  10.1007/s12104-009-9156-6
- Data Source
  KAKENHI-PROJECT-21590040
[Journal Article] Evidence for the direct interaction of spermine with the inwardly rectifying potassium channel2009
- Author(s)
  Osawa M
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 26117-26126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20051005
[Journal Article] Amino acidselective cross-saturation method foridentification of proximal residue pairsin a protein-protein complex2008
- Author(s)
  Igarashi S., Osawa M., Takeuchi K., Ozawa S., Shimada I.
- Journal Title
  
  J Am Chem Soc. 130
  
  Pages: 12168-12176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590037
[Journal Article] Mechanism of mRNA deadenylation : evidence for a molecular interplaybetween translation termination factoreRF3 and mRNA deadenylases2007
- Author(s)
  Funakoshi Y, Doi Y, Hosoda N, Uchida N,Osawa M, Shimada I, Tsujimoto M,Suzuki T, Katada T, Hoshino S.
- Journal Title
  
  Genes Dev. 21(23)
  
  Pages: 3135-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590037
[Journal Article] Nickel binding to NikA : anadditional binding site reconcilesspectroscopy, calorimetry andcrystallography2007
- Author(s)
  Addy C, Ohara M, Kawai F, Kidera A,Ikeguchi M, Fuchigami S, Osawa M,Shimada I, Park SY, Tame JR andHeddle JG.
- Journal Title
  
  Acta Crystallogr D BiolCrystallogr 63
  
  Pages: 221-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590037
[Journal Article] Structural insights into activation ofphosphatidylinositol 4-kinase (Pik1) byyeast frequenin (Frq1)2007
- Author(s)
  Strahl T, Huttner IG, Lusin JD, OsawaM, King D, Thorner J, Ames JB.
- Journal Title
  
  J Biol Chem. 282(42)
  
  Pages: 30949-59
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590037
[Journal Article] Structuralbasis of the collagen-binding mode ofdiscoidin domain receptor 22007
- Author(s)
  Ichikawa O, Osawa M, Nishida N,Goshima N, and Shimada I.
- Journal Title
  
  EMBO J 26
  
  Pages: 4168-4176
- Data Source
  KAKENHI-PROJECT-19590037
[Journal Article] Mg^<2+> and Ca^<2+> differentially regulate DNA binding and dimerization of DREAM.2005
- Author(s)
  Osawa M
- Journal Title
  
  J.Biol.Chem. 280・18
  
  Pages: 18008-18014
- Data Source
  KAKENHI-PROJECT-17053005
[Journal Article] Mg^<2+> and Ca^<2+> differentially regulate DNA binding and dimerization of DREAM.2005
- Author(s)
  Osawa M
- Journal Title
  
  J.Biol.Chem. 280・18
  
  Pages: 18008-18014
- Data Source
  KAKENHI-PROJECT-17026005
[Journal Article] Mg^<2+> and Ca^<2+> differentially regulate DNA binding and dimerization of DREAM.2005
- Author(s)
  Osawa M, Dace A, Tong KI, Valiveti A, Ikura M, Ames JB.
- Journal Title
  
  J.Biol.Chem. 280・18
  
  Pages: 18008-18014
- Data Source
  KAKENHI-PROJECT-16790032
[Presentation] B型肝炎ウイルスに直接作用する胆汁酸誘導体による新規治療薬の開発2023
- Author(s)
  奥村彰規，山下ユキコ，井口裕介，池田和由，横川真梨子，大澤匡範，宇根瑞穂，伊藤清顕
- Organizer
  第44回胆汁酸研究会
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] 14-3-3ζによる転写因子FOXO3aの阻害メカニズムの解明2023
- Author(s)
  榎本翔太, 桑山知也, 中塚将一, 横川真梨子, 河津光作, 中村吏佐, 木村友美, 田辺幹雄, 千田俊哉, 齋藤潤, 佐谷秀行, 大澤匡範
- Organizer
  第46回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] NMRを活用したSARS-CoV-2スパイクタンパク質とhACE2の相互作用を標的とするSARS-CoV-2侵入阻害化合物の分子設計2023
- Author(s)
  横川真梨子, 堀内まほろ, 金一駿希, 大竹帝河, 米澤朋起, 清水祐吾, 池田和由, 山本雄一朗, 酒井祥太, 野口耕司, 深澤征義, 大澤匡範
- Organizer
  第23回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] 14-3-3ζによる転写因子FOXO3aの阻害メカニズムの解明2023
- Author(s)
  榎本翔太, 桑山知也, 中塚将一, 横川真梨子, 河津光作, 中村吏佐, 木村友美, 田辺幹雄, 千田俊哉, 齋藤潤, 佐谷秀行，大澤匡範
- Organizer
  第62回NMR討論会
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] NMRを活用したSARS-CoV-2スパイクタンパク質とhACE2の相互作用を標的とするSARS-CoV-2侵入阻害化合物の分子設計2023
- Author(s)
  横川真梨子, 堀内まほろ, 金一駿希, 大竹帝河, 米澤朋起, 清水祐吾, 池田和由, 山本雄一朗, 酒井祥太, 野口耕司, 深澤征義, 大澤匡範
- Organizer
  第23回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] NMRを活用したSARS-CoV-2スパイクタンパク質とhACE2の相互作用を標的とするSARS-CoV-2侵入阻害化合物の分子設計2023
- Author(s)
  横川真梨子, 堀内まほろ, 金一駿希, 大竹帝河, 米澤朋起, 清水祐吾, 池田和由, 山本雄一朗, 酒井祥太, 野口耕司, 深澤征義, 大澤匡範
- Organizer
  第23回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] タンパク質-タンパク質相互作用をターゲットとした感染阻害大環状物質の探索と構造活性相関解析2023
- Author(s)
  米澤朋起, 清水祐吾, 池田和由, 山本雄一朗, 野口耕司, 酒井祥太, 深澤征義, 浅見仁太, 清水敏之, 大戸梅治, 横川真梨子, 大澤匡範
- Organizer
  第51回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] Structural basis of the inhibition of the Keap1-Nrf2 interaction by novel PPI inhibitors discovered by machine learning2023
- Author(s)
  Kojima Koujin, Ishida Hanako, Harada Ayaka, Yonezawa Tomoki, Shimizu Yugo, Ikeda Kazuyoshi, Yokogawa Mariko, Osawa Masanori
- Organizer
  CBI学会2023年大会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] ALSの原因となるTDP-43沈殿を抑制するRNAの創製2023
- Author(s)
  西村錬, 西田優理華, 横川真梨子, 坂上史佳, 横田隆徳, 大澤匡範
- Organizer
  第20回次世代を担う若手のためのフィジカル・ファーマフォーラム (PPF2023)
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] 14-3-3ζによる転写因子FOXO3aの阻害メカニズムの解明2023
- Author(s)
  榎本翔太，桑山知也，中塚将一，横川真梨子，河津光作，中村吏佐，木村友美，田辺幹雄，千田俊哉，齋藤潤，佐谷秀行，大澤匡範
- Organizer
  第62回NMR討論会
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] Structural insights into the inhibitory mechanism of transcription factor FOXO3a by phosphorylation and 14-3-3ζ2023
- Author(s)
  榎本翔太，桑山知也，中塚将一，横川真梨子，河津光作，中村吏佐，木村友美，田辺幹雄，千田俊哉，齋藤潤，佐谷秀行，大澤匡範
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] リン酸化および14-3-3ζの結合による転写因子FOXO3aの機能抑制機構の解明2023
- Author(s)
  榎本翔太，桑山知也，横川真梨子，中塚将一，河津光作，中村吏佐，木村友美，齋藤潤，佐谷秀行，大澤匡範
- Organizer
  PPF2023　第20回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] Discovery of the middle-sized compounds inhibiting the SARS-CoV-2 viral entry, using in silico approach and NMR analysis2023
- Author(s)
  Yokogawa M, Horiuchi H, Kaneichi S, Otake T, Yonezawa T, Shimizu Y, Ikeda K, Yamamoto Y, Sakai S, Noguchi K, Fukasawa M, Osawa M
- Organizer
  CBI学会2023年大会
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] タンパク質-タンパク質相互作用をターゲットとした感染阻害大環状物質の探索と構造活性相関解析2023
- Author(s)
  米澤朋起, 清水祐吾, 池田和由, 山本雄一朗, 野口耕司, 酒井祥太, 深澤征義, 浅見仁太, 清水敏之, 大戸梅治, 横川真梨子, 大澤匡範
- Organizer
  第51回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] SARS-CoV-2スパイクタンパク質に結合してSARS-CoV-2の侵入を阻害する化合物の創製2023
- Author(s)
  金一駿希，横川真梨子，堀内まほろ，大竹帝河，米澤朋起，清水祐吾，池田和由，山本雄一朗，酒井祥太，野口耕司，深澤征義，大澤匡範
- Organizer
  第62回NMR討論会
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] AH-337 is a novel bile acid derivative designed to inhibit HBV entry2023
- Author(s)
  Okumura A, Yamashita Y, Iguchi Y, Yokogawa M, Ohashi H, Arai J, Umezawa K, Ikeda K, Osawa M, Watashi K, Wakita T, Une M, Ito K
- Organizer
  2023 International HBV Meeting
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] ALSの原因となるTDP-43の沈殿形成を抑制するRNAの探索2023
- Author(s)
  西田優理華、西村錬、横川真梨子、坂上史佳、横田隆徳、大澤匡範
- Organizer
  第６７回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] NMR解析により得られたKeap1-Nrf2のPPI阻害化合物のKeap1結合の構造基盤2023
- Author(s)
  小島行人，石田英子，原田彩佳，米澤朋起，清水祐吾，池田和由，横川真梨子，大澤匡範
- Organizer
  第62回NMR討論会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] Oolonghomobisflavan CによるB型肝炎ウイルス阻害機構の解明2023
- Author(s)
  石場智彬，横川真梨子，横田旭美，大澤匡範
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] hACE2に結合してSARS-CoV-2の侵入を阻害する化合物の創製2023
- Author(s)
  横川真梨子，堀内まほろ，金一駿希，大竹帝河，米澤朋起，清水祐吾，池田和由，山本雄一朗，酒井祥太，野口耕司，深澤征義，大澤匡範
- Organizer
  第62回NMR討論会
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] SARS-CoV-2スパイクタンパク質に結合してSARS-CoV-2の侵入を阻害する化合物の創製2023
- Author(s)
  金一駿希, 横川真梨子, 堀内まほろ,大竹帝河, 米澤朋起, 清水祐吾, 池田和由, 山本雄一朗, 酒井祥太, 野口耕司, 深澤征義, 大澤匡範
- Organizer
  第62回NMR討論会
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] 14-3-3ζによる転写因子FOXO3aの阻害メカニズムの解明2023
- Author(s)
  榎本翔太, 桑山知也, 中塚将一, 横川真梨子, 河津光作, 中村吏佐, 木村友美, 田辺幹雄, 千田俊哉, 齋藤潤, 佐谷秀行，大澤匡範
- Organizer
  第62回NMR討論会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] B-cell translocation gene 2 (BTG2) によるCaf1依存的なpoly(A)分解の促進機構の解明2023
- Author(s)
  片岡奈緒, 横川真梨子, 石井裕一郎, 城えりか, 高嶋大翔, 沢崎綾一, 寒河江彪流, 尾上耕一, 星野真一, 大澤匡範
- Organizer
  第46回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] ALSの原因となるTDP-43沈殿を抑制するRNAの創製2023
- Author(s)
  西村錬，西田優理華，横川真梨子，坂上史佳，横田隆徳，大澤匡範
- Organizer
  PPF2023　第20回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] hACE2に結合してSARS-CoV-2の侵入を阻害する化合物の創製2023
- Author(s)
  横川真梨子, 堀内まほろ, 金一駿希, 大竹帝河, 米澤朋起, 清水祐吾, 池田和由, 山本雄一朗, 酒井祥太, 野口耕司, 深澤征義, 大澤匡範
- Organizer
  第62回NMR討論会
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] リン酸化および14-3-3ζの結合による転写因子FOXO3aの機能抑制機構の解明2023
- Author(s)
  榎本翔太, 桑山知也, 横川真梨子, 中塚将一, 河津光作, 中村吏佐, 木村友美, 齋藤潤, 佐谷秀行, 大澤匡範
- Organizer
  第20回次世代を担う若手のためのフィジカル・ファーマフォーラム (PPF2023)
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] 14-3-3ζによる転写因子FOXO3aの阻害メカニズムの解明2023
- Author(s)
  榎本翔太, 桑山知也, 中塚将一, 横川真梨子, 河津光作, 中村吏佐, 木村友美, 田辺幹雄, 千田俊哉, 齋藤潤, 佐谷秀行, 大澤匡範
- Organizer
  第46回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] ALSの原因となるTDP-43沈殿を抑制するRNAの創製2023
- Author(s)
  西村錬, 西田優理華, 横川真梨子, 坂上史佳, 横田隆徳, 大澤匡範
- Organizer
  第20回次世代を担う若手のためのフィジカル・ファーマフォーラム (PPF2023)
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] HBV PreS1/NTCP相互作用を標的とした阻害剤簡易スクリーニング系の構築2023
- Author(s)
  堀渕慶太, 入間田早瑛, 山本雄一朗, 横川真梨子, 清水祐吾, 米澤朋起, 池田和由, 浅見仁太,清水敏之, 大戸梅治, 深澤征義, 大澤匡範, 野口耕司
- Organizer
  第６７回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] NMR解析により得られたKeap1-Nrf2のPPI阻害化合物のKeap1結合の構造基盤2023
- Author(s)
  小島行人，石田英子，原田彩佳，米澤朋起，清水祐吾，池田和由，横川真梨子，大澤匡範
- Organizer
  第62回NMR討論会
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] HBV PreS1/NTCP相互作用を標的とした阻害剤簡易スクリーニング系の構築2023
- Author(s)
  堀渕慶太, 入間田早瑛, 山本雄一朗, 横川真梨子, 清水祐吾, 米澤朋起, 池田和由, 浅見仁太,清水敏之, 大戸梅治, 深澤征義, 大澤匡範, 野口耕司
- Organizer
  第６７回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] Structural basis of the inhibition of the Keap1-Nrf2 interaction by novel PPI inhibitors discovered by machine learning2023
- Author(s)
  Koujin Kojima，Hanako Ishida，Ayaka Harada，Tomoki Yonezawa，Yugo Shimizu，Kazuyoshi Ikeda，Mariko Yokogawa，Masanori Osawa
- Organizer
  CBI学会2023年大会
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] NMR解析により得られたKeap1-Nrf2のPPI阻害化合物のKeap1結合の構造基盤2023
- Author(s)
  小島行人，石田英子，原田彩佳，米澤朋起，清水祐吾，池田和由，横川真梨子，大澤匡範
- Organizer
  第62回NMR討論会
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] NMRを活用したSARS-CoV-2スパイクタンパク質とhACE2の相互作用を標的とするSARS-CoV-2侵入阻害化合物の分子設計2023
- Author(s)
  横川真梨子, 堀内まほろ, 金一駿希, 大竹帝河, 米澤朋起, 清水祐吾, 池田和由, 山本雄一朗, 酒井祥太, 野口耕司, 深澤征義, 大澤匡範
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] Oolonghomobisflavan CによるB型肝炎ウイルス阻害機構の解明2023
- Author(s)
  石場智彬, 横川真梨子, 横田旭美, 大澤匡範
- Organizer
  日本薬学会第143回年会
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] タンパク質-タンパク質相互作用をターゲットとした感染阻害大環状物質の探索と構造活性相関解析2023
- Author(s)
  米澤朋起，清水祐吾，池田和由，山本雄一朗，野口耕司，酒井祥太，深澤征義，横川真梨子，大澤匡範
- Organizer
  第51回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] NMRを活用したSARS-CoV-2スパイクタンパク質とhACE2の相互作用を標的とするSARS-CoV-2侵入阻害化合物の分子設計2023
- Author(s)
  横川真梨子, 堀内まほろ, 金一駿希, 大竹帝河, 米澤朋起, 清水祐吾, 池田和由, 山本雄一朗, 酒井祥太, 野口耕司, 深澤征義, 大澤匡範
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] Structural mechanism for the acceleration of the Caf1-dependent deadenylation of mRNA by BTG22023
- Author(s)
  片岡奈緒，横川真梨子，石井裕一郎，城えりか，高嶋大翔，沢崎綾一，寒河江彪流，尾上耕一，星野真一，大澤匡範
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] Discovery of the middle-sized compounds inhibiting the SARS-CoV-2 viral entry, using in silico approach and NMR analysis2023
- Author(s)
  横川真梨子, 堀内まほろ, 金一駿希, 大竹帝河, 米澤朋起, 清水祐吾, 池田和由, 山本雄一朗, 酒井祥太, 野口耕司, 深澤征義, 大澤匡範
- Organizer
  CBI学会2023年大会
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] ALSの原因となるTDP-43の沈殿形成を抑制するRNAの探索2023
- Author(s)
  西田優理華、西村錬、横川真梨子、坂上史佳、横田隆徳、大澤匡範
- Organizer
  第６７回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] SARS-CoV-2スパイクタンパク質に結合してSARS-CoV-2の侵入を阻害する化合物の創製2023
- Author(s)
  金一駿希，横川真梨子，堀内まほろ，大竹帝河，米澤朋起，清水祐吾，池田和由，山本雄一朗，酒井祥太，野口耕司，深澤征義，大澤匡範
- Organizer
  第62回NMR討論会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] HBV PreS1/NTCP相互作用に対する阻害剤簡易スクリーニング系の構築2023
- Author(s)
  堀渕慶太，入間田早瑛，山本雄一朗，横川真梨子，清水祐吾，米澤朋起，池田和由，浅見仁太，清水敏之，大戸梅治，深澤征義，大澤匡範，野口耕司
- Organizer
  第67回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] 阻害剤のインシリコスクリーニング2023
- Author(s)
  米澤朋起, 清水祐吾, 池田和由, 山本雄一朗, 野口耕司, 酒井祥太, 深澤征義, 横川真梨子, 大澤匡範
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] COVID-19の原因となるタンパク質-タンパク質相互作用を標的とする合成中分子阻害剤のインシリコスクリーニング2023
- Author(s)
  米澤朋起, 清水祐吾, 池田和由, 山本雄一朗, 野口耕司, 酒井祥太, 深澤征義, 横川真梨子, 大澤匡範
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] hACE2に結合してSARS-CoV-2の侵入を阻害する化合物の創製2023
- Author(s)
  横川真梨子，堀内まほろ，金一駿希，大竹帝河，米澤朋起，清水祐吾，池田和由，山本雄一朗，酒井祥太，野口耕司，深澤征義，大澤匡範
- Organizer
  第62回NMR討論会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] ALSの原因となるTDP-43の沈殿形成を抑制するRNAの探索2023
- Author(s)
  西田優理華，西村錬，横川真梨子，坂上史佳，横田隆徳，大澤匡範
- Organizer
  第67回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] Discovery of the middle-sized compounds inhibiting the SARS-CoV-2 viral entry, using in silico approach and NMR analysis2023
- Author(s)
  Mariko YOKOGAWA, Mahoro HORIUCHI, Shunki KANEICHI, Taiga OTAKE, Tomoki YONEZAWA, Yugo SHIMIZU, Kazuyoshi IKEDA, Yuichiro YAMAMOTO, Shota SAKAI, Kohji NOGUCHI, Masayoshi FUKASAWA, Masanori OSAWA
- Organizer
  CBI学会2023年大会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] B-cell translocation gene 2 (BTG2) によるCaf1依存的なpoly(A)分解の促進機構の解明2023
- Author(s)
  片岡奈緒, 横川真梨子, 石井裕一郎, 城えりか, 高嶋大翔, 沢崎綾一, 寒河江彪流, 尾上耕一, 星野真一, 大澤匡範
- Organizer
  第46回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] リン酸化および14-3-3ζの結合による転写因子FOXO3aの機能抑制機構の解明2023
- Author(s)
  榎本翔太, 桑山知也, 横川真梨子, 中塚将一, 河津光作, 中村吏佐, 木村友美, 齋藤潤, 佐谷秀行, 大澤匡範
- Organizer
  第20回次世代を担う若手のためのフィジカル・ファーマフォーラム (PPF2023)
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] Structural basis of the inhibition of the Keap1-Nrf2 interaction by novel PPI inhibitors discovered by machine learning2023
- Author(s)
  Kojima K, Ishida H, Harada A, Yonezawa T, Shimizu Y, Ikeda K, Yokogawa M, Osawa M
- Organizer
  CBI学会2023年大会
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] Paip2A inhibits translation by competitively binding to the RNA recognition motifs of poly(A)-binding protein C1 and promoting its dissociation from the poly(A) tail2022
- Author(s)
  Takeru Sagae, Mariko Yokogawa, Ryoichi Sawazaki, Yuichiro Ishii, Nao Hosoda, Shin-ichi Hoshino, Shunsuke Imai, Ichio Shimada, Masanori Osawa
- Organizer
  日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] Structural insights into the inhibitory mechanism of transcription factor FOXO3a by 14-3-3ζ2022
- Author(s)
  桑山知也，中塚将一，横川真梨子，河津光作，中村吏佐，木村友美，田辺幹雄，千田俊哉，齋藤潤，佐谷秀行，大澤匡範
- Organizer
  第61回NMR討論会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] Paip2 competitively dissociates PABPC1 from poly(A) by accessing RRM2 of the poly(A)-bound PABPC12022
- Author(s)
  Takeru Sagae, Mariko Yokogawa, Ryoichi Sawazaki, Yuichiro Ishii, Nao Hosoda, Shin-ichi Hoshino, Shunsuke Imai, Ichio Shimada, Masanori Osawa
- Organizer
  日本蛋白質科学会学会年会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] Paip2A inhibits translation by competitively binding to the RNA recognition motifs of poly(A)-binding protein C1 and promoting its dissociation from the poly(A) tail2022
- Author(s)
  Takeru Sagae, Mariko Yokogawa, Ryoichi Sawazaki, Yuichiro Ishii, Nao Hosoda, Shin-ichi Hoshino, Shunsuke Imai, Ichio Shimada, Masanori Osawa
- Organizer
  International Council on Magnetic Resonance in Biological Systems
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] PoSSuMds Update : Addition Of Clinical Candidates And COVID-19 Clinical Trials Information2022
- Author(s)
  Tomoki Yonezawa, Yuko Tsuchiya, Masanori Osawa, Kentaro Tomii, Kazuyoshi Ikeda
- Organizer
  The Chem-Bio Informatics Society
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] 新型コロナウイルスSARS-CoV-2スパイクタンパク質阻害剤の探索2022
- Author(s)
  小林明日香, 祝部真澄, 山本雄一朗, 村江真奈, 清水芳実, 酒井祥太, 深澤征義, 米澤朋起, 清水祐吾, 池田和由, 横川真梨子, 大澤匡範, 野口耕司
- Organizer
  第34回微生物シンポジウム
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] Paip2A inhibits translation by competitively binding to the RNA recognition motifs of poly(A)-binding protein C1 and promoting its dissociation from the poly(A) tail2022
- Author(s)
  寒河江彪流，横川真梨子，沢崎綾一，石井裕一郎，細田直，星野真一，今井駿輔，嶋田一夫，大澤匡範
- Organizer
  第61回NMR討論会
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] ヴァーチャルライブラリーを用いたタンパク質-タンパク質阻害と膜透過性を考慮した中分子ライブラリー構築2022
- Author(s)
  米澤朋起，大澤匡範，大田雅照，本間光貴，池田和由
- Organizer
  第50回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] Paip2A inhibits translation by competitively binding to the RNA recognition motifs of poly(A)-binding protein C1 and promoting its dissociation from the poly(A) tail2022
- Author(s)
  Takeru Sagae, Mariko Yokogawa, Ryoichi Sawazaki, Yuichiro Ishii, Nao Hosoda, Shin-ichi Hoshino, Shunsuke Imai, Ichio Shimada, Masanori Osawa
- Organizer
  日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] NMRによるPPI 阻害化合物と標的タンパク質との相互作用の構造生物学的解析とドラッグデザイン2022
- Author(s)
  小島行人，清水祐吾，米澤朋起，池田和由，原田彩佳，横川真梨子，大澤匡範
- Organizer
  第19回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] 14-3-3ζによる転写因子FOXO3aの阻害メカニズムの解明2022
- Author(s)
  桑山知也，中塚将一，横川真梨子，河津光作，中村吏佐，木村友美，田辺幹雄，千田俊哉，齋藤潤，佐谷秀行，大澤匡範
- Organizer
  第61回NMR討論会
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] Oolonghomobisflavan CによるB型肝炎ウイルス阻害機構の解明2022
- Author(s)
  石場智彬，横川真梨子，横田旭美，大澤匡範
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] Paip2 competitively dissociates PABPC1 from poly(A) by accessing RRM2 of the poly(A)-bound PABPC12022
- Author(s)
  Sagae T, Yokogawa M, Sawazaki R, Ishii Y, Hosoda N, Hoshino S, Imai S, Shimada I, Osawa M
- Organizer
  日本蛋白質科学会学会年会
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] 創薬プロセスにおいて創出される化合物の高速な特許性予測手法の開発2022
- Author(s)
  清水祐吾、大澤匡範、池田和由、幸瞳、大田雅照、本間光貴
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] Bile acid derivative INT-767 interacts with the preS1 of HBsAg2022
- Author(s)
  Okumura A, Yokogawa M, Yamashita Y, Iguchi Y, Ohashi H, Une M, Umezawa K, Watashi K, Wakita T, Yoneda M, Osawa M, Ito K
- Organizer
  2022 International HBV Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] 新型コロナウイルスSARS-CoV-2スパイクタンパク質阻害剤の探索2022
- Author(s)
  小林明日香, 祝部真澄, 山本雄一朗, 村江真奈, 清水芳実, 酒井祥太, 深澤征義, 米澤朋起, 清水祐吾, 池田和由, 横川真梨子, 大澤匡範, 野口耕司
- Organizer
  第34回微生物シンポジウム
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] Paip2A inhibits translation by competitively binding to the RNA recognition motifs of poly(A)-binding protein C1 and promoting its dissociation from the poly(A) tail2022
- Author(s)
  Osawa M
- Organizer
  The 7th International Symposium on Drug Discovery and Design by NMR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] Paip2A inhibits translation by competitively binding to the RNA recognition motifs of poly(A)-binding protein C1 and promoting its dissociation from the poly(A) tail2022
- Author(s)
  Masanori Osawa
- Organizer
  The 7th International Symposium on Drug Discovery and Design by NMR
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] Paip2 competitively dissociates PABPC1 from poly(A) by accessing RRM2 of the poly(A)-bound PABPC12022
- Author(s)
  Takeru Sagae, Mariko Yokogawa, Ryoichi Sawazaki, Yuichiro Ishii, Nao Hosoda, Shin-ichi Hoshino, Shunsuke Imai, Ichio Shimada, Masanori Osawa
- Organizer
  日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] Paip2A inhibits translation by competitively binding to the RNA recognition motifs of poly(A)-binding protein C1 and promoting its dissociation from the poly(A) tail2022
- Author(s)
  Takeru Sagae, Mariko Yokogawa, Ryoichi Sawazaki, Yuichiro Ishii, Nao Hosoda, Shin-ichi Hoshino, Shunsuke Imai, Ichio Shimada, Masanori Osawa
- Organizer
  International Council on Magnetic Resonance in Biological Systems
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] Paip2A inhibits translation by competitively binding to the RNA recognition motifs of poly(A)-binding protein C1 and promoting its dissociation from the poly(A) tail2022
- Author(s)
  Sagae T, Yokogawa M, Sawazaki R, Ishii Y, Hosoda N, Hoshino S, Imai S, Shimada I, Osawa M
- Organizer
  日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] 新型コロナウイルス感染症 (COVID-19) の原因PPIを標的とする合成中分子阻害剤の合理的設計プラットフォーム2022
- Author(s)
  大澤匡範
- Organizer
  第5回 Translational and Regulatory Sciencesシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] ヴァーチャルライブラリーを用いたタンパク質-タンパク質阻害と膜透過性を考慮した中分子ライブラリー構築2022
- Author(s)
  米澤朋起，大澤匡範，大田雅照，本間光貴，池田和由
- Organizer
  第50回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] AI・ケモインフォマティクス・構造生物学の連携による新規Protein-Protein Interaction(PPI)阻害化合物の探索2022
- Author(s)
  大澤匡範
- Organizer
  日本神経学会主催産官学創薬スクール
- Invited
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] Structural insights into the inhibitory mechanism of transcription factor FOXO3a by 14-3-3ζ2022
- Author(s)
  桑山知也，中塚将一，横川真梨子，河津光作，中村吏佐，木村友美，田辺幹雄，千田俊哉，齋藤潤，佐谷秀行，大澤匡範
- Organizer
  第61回NMR討論会
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] NMRを活用したSARS-CoV-2スパイクタンパク質とhACE2の相互作用を標的とするSARS-CoV-2侵入阻害化合物の分子設計2022
- Author(s)
  横川真梨子, 堀内まほろ, 金一駿希, 大竹帝河, 米澤朋起, 清水祐吾, 池田和由, 山本雄一朗, 酒井祥太, 野口耕司, 深澤征義, 大澤匡範
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] 胆汁酸誘導体によるB型肝炎ウイルス感染制御2022
- Author(s)
  奥村彰規，伊藤清顕，横川真梨子，山下ユキコ, 井口裕介, 池田和由，大澤匡範, 宇根瑞穂，米田政志
- Organizer
  第43回胆汁酸研究会
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] NMRによるPPI 阻害化合物と標的タンパク質との相互作用の構造生物学的解析とドラッグデザイン2022
- Author(s)
  小島行人，清水祐吾，米澤朋起，池田和由，原田彩佳，横川真梨子，大澤匡範
- Organizer
  第19回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] COVID-19の原因となるタンパク質-タンパク質相互作用を標的とする合成中分子阻害剤のin silico解析2022
- Author(s)
  米澤朋起、清水祐吾、池田和由、山本雄一朗、野口耕司、酒井祥太、深澤征義、横川真梨子、大澤匡範
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] COVID-19の原因となるタンパク質-タンパク質相互作用を標的とする合成中分子阻害剤のインシリコスクリーニング2022
- Author(s)
  米澤朋起, 清水祐吾, 池田和由, 山本雄一朗, 野口耕司, 酒井祥太, 深澤征義, 横川真梨子, 大澤匡範
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] 新型コロナウイルスSARS-CoV-2スパイクタンパク質阻害剤の探索2022
- Author(s)
  小林明日香，祝部真澄，山本雄一朗，村江真奈，清水芳実，酒井祥太，深澤征義，米澤朋起，清水祐吾，池田和由，横川真梨子，大澤匡範，野口耕司
- Organizer
  第34回微生物シンポジウム
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] COVID-19の原因となるタンパク質-タンパク質相互作用を標的とする合成中分子阻害剤のin silico解析2022
- Author(s)
  米澤朋起、清水祐吾、池田和由、山本雄一朗、野口耕司、酒井祥太、深澤征義、横川真梨子、大澤匡範
- Organizer
  日本薬学会第142回年会 (オンライン)
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] Paip2A inhibits translation by competitively binding to the RNA recognition motifs of poly(A)-binding protein C1 and promoting its dissociation from the poly(A) tail2022
- Author(s)
  寒河江彪流，横川真梨子，沢崎綾一，石井裕一郎，細田直，星野真一，今井駿輔，嶋田一夫，大澤匡範
- Organizer
  第61回NMR討論会
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] NMRによるPPI 阻害化合物と標的タンパク質との相互作用の構造生物学的解析とドラッグデザイン2022
- Author(s)
  小島行人，清水祐吾，米澤朋起，池田和由，原田彩佳，横川真梨子，大澤匡範
- Organizer
  第19回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] PoSSuMds Update : Addition Of Clinical Candidates And COVID-19 Clinical Trials Information2022
- Author(s)
  Yonezawa T, Tsuchiya Y, Osawa M, Tomii K, Ikeda K
- Organizer
  The Chem-Bio Informatics Society
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] Paip2A inhibits translation by competitively binding to the RNA recognition motifs of poly(A)-binding protein C1 and promoting its dissociation from the poly(A) tail2022
- Author(s)
  寒河江彪流，横川真梨子，沢崎綾一，石井裕一郎，細田直，星野真一，今井駿輔，嶋田一夫，大澤匡範
- Organizer
  第61回NMR討論会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] Paip2A inhibits translation by competitively binding to the RNA recognition motifs of poly(A)-binding protein C1 and promoting its dissociation from the poly(A) tail2022
- Author(s)
  Sagae T,Yokogawa M, Sawazaki R, Ishii Y, Hosoda N, Hoshino S, Imai S,Shimada I, Osawa M
- Organizer
  International Council on Magnetic Resonance in Biological Systems
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24323
[Presentation] 医薬品特許化合物データベースの構築とその構造発生への応用2022
- Author(s)
  清水祐吾, 幸瞳, 大田雅照,本間光貴, 大澤匡範, 池田和由
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] Structural Mechanism of Translational Repression by PABP-interacting protein 22021
- Author(s)
  Takeru Sagae, Mariko Yokogawa, Ryoichi Sawazaki, Nao Hisoda, Shin-ichi Hoshino, Masanori Osawa
- Organizer
  ISMAR-APNMR-NMRSJ-SEST 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] Gating-modifier toxin APETx1による電位依存性カリウムイオンチャネルhERG阻害機構の解析2021
- Author(s)
  大澤匡範
- Organizer
  BINDS-PDBj講習会「PDBから見てわかるタンパク質の最新研究」
- Invited
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] B-cell translocation gene 2 (BTG2)によるポリA分解促進機構の解明2021
- Author(s)
  石井裕一郎、横川真梨子、城えりか、高嶋大翔、沢崎綾一、寒河江彪流、尾上耕一、星野真一、大澤匡範
- Organizer
  日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] リン酸化および14-3-3ζによる転写因子FOXO3aの阻害メカニズムの解明2021
- Author(s)
  桑山知也, 中塚将一, 横川真梨子, 河津光作, 中村吏佐, 木村友美, 田辺幹雄, 齋藤潤, 千田俊哉, 佐谷秀行, 大澤匡範
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] リン酸化および14-3-3ζによる転写因子FoxO3aの阻害メカニズムの解明2021
- Author(s)
  中塚将一、桑山知也、横川真梨子、河津光作、中村吏佐、木村友美、田辺幹雄、千田俊哉、齋藤潤、佐谷秀行、大澤匡範
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] Structural Mechanism of Translational Repression by PABP-interacting Protein 22021
- Author(s)
  Takeru Sagae, Mariko Yokogawa, Ryoichi Sawazaki, Nao Hosoda, Shin-ichi Hoshino, Masanori Osawa
- Organizer
  ISMAR-APNMR-NMRSJ-SEST 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] Gating-modifier toxin APETx1による電位依存性カリウムイオンチャネルhERG阻害機構の解析2021
- Author(s)
  松村一輝、下村拓史、久保義弘、岡貴之、小林直宏、今井駿輔、簗瀬尚美、秋元まどか、福田昌弘、横川真梨子、池田和由、栗田順一、西村善文、嶋田一夫、大澤匡範
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] 分子内ジスルフィド結合による電位依存性K+チャネルの膜電位依存的構造変化機構の解明2021
- Author(s)
  石川貴大、原田彩佳、横川真梨子、前田知輝、日向寺孝禎、藤田浩平、野崎智裕、嶋田一夫、大澤匡範
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] 分子内ジスルフィド結合による電位依存性K+チャネルの膜電位依存的構造変化機構の解明2021
- Author(s)
  石川貴大、原田彩佳、横川真梨子、前田知輝、日向寺孝禎、藤田浩平、野崎智裕、嶋田一夫、大澤匡範
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] 分子内ジスルフィド結合による電位依存性K+チャネルの膜電位依存的構造変化機構の解明2021
- Author(s)
  原田彩佳、石川貴大、横川真梨子、前田知輝、日向寺孝禎、藤田浩平、野崎智裕、嶋田一夫、大澤匡範
- Organizer
  日本薬学会　第141年会
- Data Source
  KAKENHI-PUBLICLY-19H04973
[Presentation] 電位依存性K+チャネルの動作メカニズムとペプチドによる阻害メカニズム2021
- Author(s)
  大澤匡範
- Organizer
  第28回日本血液代替物学会年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] Gating-modifier toxin APETx1による電位依存性カリウムイオンチャネルhERG阻害機構の解析2021
- Author(s)
  大澤匡範
- Organizer
  生理学研究所研究会「構造情報を基盤とした膜機能分子の生理機能理解に向けて」
- Invited
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] Gating-modifier toxin APETx1による電位依存性カリウムイオンチャネルhERG阻害機構の解析2021
- Author(s)
  松村一輝, 下村拓史, 久保義弘, 岡貴之, 小林直宏, 今井駿輔, 簗瀬尚美, 秋元まどか, 福田昌弘, 横川真梨子, 池田和由, 栗田順一, 西村善文, 嶋田一夫, 大澤匡範
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] B-cell translocation gene 2 (BTG2)によるポリA分解促進機構の解明2021
- Author(s)
  石井裕一郎, 横川真梨子, 城えりか, 高嶋大翔, 沢崎綾一, 寒河江彪流, 尾上耕一, 星野真一, 大澤匡範
- Organizer
  第94回日本生化学大会年会
- Data Source
  KAKENHI-PROJECT-21K06494
[Presentation] 分子内ジスルフィド結合による電位依存性K+チャネルの膜電位依存的構造変化機構の解明2021
- Author(s)
  原田彩佳, 石川貴大, 横川真梨子, 前田知輝, 日向寺孝禎, 藤田浩平, 野崎智裕, 嶋田一夫, 大澤匡範
- Organizer
  日本薬学会　第141年会
- Data Source
  KAKENHI-PROJECT-18K06606
[Presentation] リン酸化および14-3-3ζによる転写因子FoxO3aの阻害メカニズムの解明2021
- Author(s)
  中塚将一、桑山知也、横川真梨子、河津光作、中村吏佐、木村友美、田辺幹夫、千田俊哉、齋藤潤、佐谷秀行、大澤匡範
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] リン酸化および14-3-3ζによる転写因子FOXO3aの阻害メカニズムの解明2021
- Author(s)
  桑山知也、中塚将一、横川真梨子、河津光作、中村吏佐、木村友美、田辺幹夫、千田俊哉、齋藤潤、佐谷秀行、大澤匡範
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H02618
[Presentation] PABP-interacting Protein 2による翻訳抑制機構の解明2020
- Author(s)
  寒河江彪流, 横川真梨子, 沢崎綾一, 細田直, 星野真一, 大澤匡範
- Organizer
  第43回　日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-19H04973
[Presentation] PABP-interacting Protein 2による翻訳抑制機構の解明2020
- Author(s)
  寒河江彪流, 横川真梨子, 沢崎綾一, 細田直, 星野真一, 大澤匡範
- Organizer
  第43回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06606
[Presentation] Structural Mechanism of Translational Repression by PABP-interacting Protein 22020
- Author(s)
  Takeru Sagae, Mariko Yokogawa, Ryoichi Sawazaki, Nao Hosoda, Shin-ichi Hoshino, Masanori Osawa
- Organizer
  第20回日本蛋白質科学会年会
- Data Source
  KAKENHI-PUBLICLY-19H04973
[Presentation] B型肝炎ウイルスの肝細胞特異的な侵入機構の解明2020
- Author(s)
  石場智彬, 横川真梨子, 横田旭美, 室井大輝, 大澤匡範
- Organizer
  第43回　日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-19H04973
[Presentation] B型肝炎ウイルスの肝細胞特異的な侵入機構の解明2020
- Author(s)
  石場智彬, 横川真梨子, 横田旭美, 室井大輝, 大澤匡範
- Organizer
  第43回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06606
[Presentation] Gating-modifier toxin APETx1による電位依存性カリウムイオンチャネルhERG阻害機構の解析2020
- Author(s)
  松村一輝, 下村拓史, 久保義弘, 岡貴之, 小林直宏, 今井駿輔, 簗瀬尚美, 秋元まどか, 福田昌弘, 横川真梨子, 池田和由, 栗田順一, 西村善文, 嶋田一夫, 大澤匡範
- Organizer
  第43回　日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-19H04973
[Presentation] Structural basis for the hepatocyte-specific entry of hepatitis B virus2020
- Author(s)
  Tomoaki Ishiba, Mariko Yokogawa, Terumi Yokota, Taiki Muroi, Masanori Osawa
- Organizer
  第20回日本蛋白質科学会年会
- Data Source
  KAKENHI-PUBLICLY-19H04973
[Presentation] Structural basis for the hepatocyte-specific entry of hepatitis B virus2020
- Author(s)
  Tomoaki Ishiba, Mariko Yokogawa, Terumi Yokota, Taiki Muroi, Masanori Osawa
- Organizer
  第20回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-18K06606
[Presentation] Gating-modifier toxin APETx1による電位依存性カリウムイオンチャネルhERG阻害機構の解析2020
- Author(s)
  松村一輝, 下村拓史, 久保義弘, 岡貴之, 小林直宏, 今井駿輔, 簗瀬尚美, 秋元まどか, 福田昌弘, 横川真梨子, 池田和由, 栗田順一, 西村善文, 嶋田一夫, 大澤匡範
- Organizer
  第43回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06606
[Presentation] Structural Mechanism of Translational Repression by PABP-interacting Protein 22020
- Author(s)
  Takeru Sagae, Mariko Yokogawa, Ryoichi Sawazaki, Nao Hosoda, Shin-ichi Hoshino, Masanori Osawa
- Organizer
  第20回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-18K06606
[Presentation] Elucidation of the inhibitory mechanism of a sea anemone toxin, APETx1, targeting a human heart voltage-gated potassium channel, hERG1.2019
- Author(s)
  松村一輝、福田昌弘、簗瀬尚美、秋元まどか、黒川洵子、横川真梨子、大澤匡範
- Organizer
  第42回　日本分子生物学会
- Data Source
  KAKENHI-PROJECT-18K06606
[Presentation] リン酸化による転写因子FOXO3aの機能抑制機構の解2019
- Author(s)
  河津光作、中塚将一、横川真梨子、中村吏佐、木村友美、齋藤潤、佐谷秀行、大澤匡範
- Organizer
  第63回　日本薬学会関東支部大会
- Data Source
  KAKENHI-PUBLICLY-19H04973
[Presentation] BTG2によるポリ A 分解促進機構の構造生物学的解明2019
- Author(s)
  高嶋大翔、城えりか、横川真梨子、沢崎綾一、寒河江彪流、尾上耕一、星野真一、大澤匡範
- Organizer
  第63回　日本薬学会関東支部大会
- Data Source
  KAKENHI-PUBLICLY-19H04973
[Presentation] BTG2によるポリ A 分解促進機構の構造生物学的解明2019
- Author(s)
  高嶋大翔、城えりか、横川真梨子、沢崎綾一、寒河江彪流、尾上耕一、星野真一、大澤匡範
- Organizer
  第63回　日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] 電位依存性K+チャネルの膜電位依存的構造変化機構の解明2019
- Author(s)
  日向寺孝禎、横川真梨子、藤田浩平、野崎智裕、嶋田一夫、大澤匡範
- Organizer
  第63回　日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] 電位依存性H+チャネルHv1のアラキドン酸による活性化促進機構の解明2019
- Author(s)
  村上玲、吉敷純、横川真梨子、松葉広昭、木村友美、川鍋陽、岡村康司、嶋田一夫、大澤匡範
- Organizer
  第63回　日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] Elucidation of the inhibitory mechanism of a sea anemone toxin, APETx1, targeting a human heart voltage-gated potassium channel, hERG12019
- Author(s)
  松村一輝、福田昌弘、簗瀬尚美、秋元まどか、黒川洵子、横川真梨子、大澤匡範
- Organizer
  第42回　日本分子生物学会
- Data Source
  KAKENHI-PUBLICLY-18H04679
[Presentation] Elucidation of the inhibitory mechanism of a sea anemone toxin, APETx1, targeting a human heart voltage-gated potassium channel, hERG12019
- Author(s)
  松村一輝、福田昌弘、簗瀬尚美、秋元まどか、黒川洵子、横川真梨子、大澤匡範
- Organizer
  第42回　日本分子生物学会
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] ヌクレオシド輸送体ENT1 の膜輸送機構の構造生物学的解明2019
- Author(s)
  岸孝一郎、福田昌弘、大澤匡範
- Organizer
  第63回　日本薬学会関東支部大会
- Data Source
  KAKENHI-PUBLICLY-18H04679
[Presentation] リン酸化による転写因子FOXO3a の機能抑制機構の解明2019
- Author(s)
  河津光作、中塚将一、横川真梨子、中村吏佐、木村友美、齋藤潤、佐谷秀行、大澤匡範
- Organizer
  第63回　日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-18K06606
[Presentation] BTG2によるポリ A 分解促進機構の構造生物学的解明2019
- Author(s)
  高嶋大翔、城えりか、横川真梨子、沢崎綾一、寒河江彪流、尾上耕一、星野真一、大澤匡範
- Organizer
  第63回　日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-18K06606
[Presentation] 電位依存性K+チャネルの膜電位依存的構造変化機構の解明2019
- Author(s)
  日向寺孝禎、横川真梨子、藤田浩平、野崎智裕、嶋田一夫、大澤匡範
- Organizer
  第63回　日本薬学会関東支部大会
- Data Source
  KAKENHI-PUBLICLY-18H04679
[Presentation] 電位依存性 K+チャネルの膜電位依存的構造変化機構の解明2019
- Author(s)
  日向寺孝禎、横川真梨子、藤田浩平、野崎智裕、嶋田一夫、大澤匡範
- Organizer
  第63回　日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-18K06606
[Presentation] 電位依存性H+ チャネルHv1のアラキドン酸による活性化促進機構の解明2019
- Author(s)
  村上玲、吉敷純、横川真梨子、松葉広昭、木村友美、川鍋陽、岡村康司、嶋田一夫、大澤匡範
- Organizer
  第63回　日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-18K06606
[Presentation] 電位依存性H+チャネルHv1のアラキドン酸による活性化促進機構の解明2019
- Author(s)
  村上玲、吉敷純、横川真梨子、松葉広昭、木村友美、川鍋陽、岡村康司、嶋田一夫、大澤匡範
- Organizer
  第63回　日本薬学会関東支部大会
- Data Source
  KAKENHI-PUBLICLY-18H04679
[Presentation] 電位依存性カリウムイオンチャネルの膜電位依存的構造変化機構の解明2018
- Author(s)
  藤田浩平, 横川真梨子, 上和田遥平, 日向寺孝禎, 野崎智裕, 嶋田一夫, 大澤匡範
- Organizer
  第62回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-18K06606
[Presentation] 電位依存性カリウムイオンチャネルの膜電位依存的構造変化機構の解明2018
- Author(s)
  藤田浩平、横川真梨子、上和田遥平、日向寺孝禎、野崎智裕、嶋田一夫、大澤匡範
- Organizer
  第62回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] Hanatoxin1による電位依存性プロトンチャネルHv1阻害機構の解明2018
- Author(s)
  中久木友哉, 横川真梨子, 泉谷俊稀, 大澤匡範
- Organizer
  第62回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-18K06606
[Presentation] Gタンパク質のファミリー選択的なK+チャネル活性制御機構の構造生物学的解明2018
- Author(s)
  加納花穂, 外山侑樹, 今井駿輔, 岩橋優太, 間瀬瑶子, 横川真梨子, 大澤匡範, 嶋田一夫
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06606
[Presentation] 電位依存性カリウムイオンチャネルの膜電位依存的構造変化機構の解明2018
- Author(s)
  藤田浩平、横川真梨子、上和田遥平、日向寺孝禎、野崎智裕、嶋田一夫、大澤匡範
- Organizer
  第62回日本薬学会関東支部大会
- Data Source
  KAKENHI-PUBLICLY-18H04679
[Presentation] Hanatoxin1による電位依存性プロトンチャネルHv1阻害機構の解明2018
- Author(s)
  中久木友哉、横川真梨子、泉谷俊稀、大澤匡範
- Organizer
  第62回日本薬学会関東支部大会
- Data Source
  KAKENHI-PUBLICLY-18H04679
[Presentation] Development of an informatics system for diversity of compound library2018
- Author(s)
  Yugo Shimizu, Masanori Osawa, Kazuyoshi Ikeda
- Organizer
  CBI学会2018年大会
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] 電位依存性カリウムイオンチャネルhERGの閉状態の安定化による、hERG開閉機構の構造生物学的解明2018
- Author(s)
  松村一輝、簗瀬尚美、秋元まどか、岩崎菜々美、坂本多穗、黒川洵子、横川真梨子、大澤匡範
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] Ｂ型肝炎ウイルスの粒子形成機構の解明2018
- Author(s)
  横川真梨子，石場智彬，池田寿子，藤田浩平，横田旭美，大澤匡範
- Organizer
  第57回NMR討論会
- Data Source
  KAKENHI-PROJECT-18K06606
[Presentation] Gating modifier toxin, APETx1Gating modifier toxin, APETx1による電位依存性カリウムイオンチャネルhERG1の阻害機構の構造生物学的解明2018
- Author(s)
  松村一輝、福田昌弘、簗瀬尚美、秋元まどか、岩崎菜々美、坂本多穗、黒川洵子、横川真梨子、大澤匡範
- Organizer
  第41回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] Gating modifier toxin, APETx1による電位依存性カリウムイオンチャネルhERG1の阻害機構の構造生物学的解明2018
- Author(s)
  松村一輝, 福田昌弘. 簗瀬尚美, 秋元まどか, 岩崎菜々美, 坂本多穗, 黒川洵子, 横川真梨子, 大澤匡範
- Organizer
  第41回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06606
[Presentation] Hanatoxin1による電位依存性プロトンチャネルHv1阻害機構の解明2018
- Author(s)
  中久木友哉，横川真梨子，泉谷俊稀，大澤匡範
- Organizer
  第2回慶應ライフサイエンスシンポジウム
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] Gating modifier toxin, APETx1による電位依存性カリウムイオンチャネルhERG1の阻害機構の構造生物学的解明2018
- Author(s)
  松村一輝、福田昌弘、簗瀬尚美、秋元まどか、岩崎菜々美、坂本多穗、黒川洵子、横川真梨子、大澤匡範
- Organizer
  第41回分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04679
[Presentation] B型肝炎ウイルスの粒子形成機構の解明2018
- Author(s)
  横川真梨子、石場智彬、池田寿子、藤田浩平、横田旭美、大澤匡範
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] Structural dynamics of potassium ion channels revealed by side-chain methyl13C-1H multiple quantum relaxation analyses.2018
- Author(s)
  Yuki Toyama, Hanaho Kano, Yoko Mase, Mariko Yokogawa, Masanori Osawa and Ichio Shimada.
- Organizer
  59th Experimental Nuclear Magnetic Resonance Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] Hanatoxin1による電位依存性プロトンチャネルHv1阻害機構の解明2018
- Author(s)
  中久木友哉、横川真梨子、泉谷俊稀、大澤匡範
- Organizer
  第62回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] Functional roles of Mg2+ binding sites in ion-dependent gating of a Mg2+ channel, MgtE, revealed by solution NMR.2018
- Author(s)
  大澤匡範
- Organizer
  第56回日本生物物理学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04679
[Presentation] 14-3-3ζと抗癌活性化合物の相互作用の構造生物学的解析2018
- Author(s)
  中村吏佐、河津光作、齋藤潤、佐谷秀行、大澤匡範
- Organizer
  第62回日本薬学会関東支部大会
- Data Source
  KAKENHI-PUBLICLY-18H04679
[Presentation] Hanatoxin1による電位依存性プロトンチャネルHv1阻害機構の解明2018
- Author(s)
  中久木友哉，横川真梨子，泉谷俊稀，大澤匡範
- Organizer
  第2回慶應ライフサイエンスシンポジウム
- Data Source
  KAKENHI-PUBLICLY-18H04679
[Presentation] 溶液NMR 法によるMg2+ チャネルMgtE の開閉機構の解明2018
- Author(s)
  大澤匡範
- Organizer
  大阪大学蛋白質研究所セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] Functional roles of Mg2+ binding sites in ion-dependent gating of a Mg2+ channel, MgtE, revealed by solution NMR.2018
- Author(s)
  丸山達朗 , 今井駿輔 , 草木迫司 , 服部素之 , 石谷隆一郎 , 濡木理 , 伊藤耕一 , Maturana Andres D. , 嶋田一夫 , 大澤匡範
- Organizer
  第57回NMR討論会
- Data Source
  KAKENHI-PUBLICLY-18H04679
[Presentation] 14-3-3ζと抗癌活性化合物の相互作用の構造生物学的解析2018
- Author(s)
  中村吏佐、河津光作、齋藤潤、佐谷秀行、大澤匡範
- Organizer
  第62回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] 電位依存性カリウムイオンチャネルの膜電位依存的構造変化機構の解明2018
- Author(s)
  藤田浩平，横川真梨子，上和田遥平，日向寺孝禎，野崎智裕，嶋田一夫，大澤匡範
- Organizer
  第2回慶應ライフサイエンスシンポジウム
- Data Source
  KAKENHI-PUBLICLY-18H04679
[Presentation] Characterization of the multimeric structure of poly(A)-binding protein on a poly(A) tail.2018
- Author(s)
  Ryoichi Sawazaki, Shunsuke Imai, Mariko Yokogawa, Nao Hosoda, Shin-ichi Hoshino, Muneyo Mio, Kazuhiro Mio, Ichio Shimada, Masanori Osawa.
- Organizer
  第18回日本蛋白質科学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04679
[Presentation] Characterization of the multimeric structure of poly(A)-binding protein on a poly(A) tail.2018
- Author(s)
  Ryoichi Sawazaki, Shunsuke Imai, Mariko Yokogawa, Nao Hosoda, Shin-ichi Hoshino, Muneyo Mio, Kazuhiro Mio, Ichio Shimada, Masanori Osawa.
- Organizer
  第18回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] Development of an informatics system for diversity of compound library2018
- Author(s)
  Yugo Shimizu, Masanori Osawa, Kazuyoshi Ikeda
- Organizer
  CBI学会2018年大会
- Data Source
  KAKENHI-PUBLICLY-18H04679
[Presentation] Structural dynamics of potassium ion channels revealed by side-chain methyl 13C-1H multiple quantum relaxation analyses2018
- Author(s)
  Yuki Toyama, Hanaho Kano, Yoko Mase, Mariko Yokogawa, Masanori Osawa, Ichio Shimada
- Organizer
  59th Experimental Nuclear Magnetic Resonance Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06606
[Presentation] Functional roles of Mg2+ binding sites in ion-dependent gating of a Mg2+ channel, MgtE, revealed by solution NMR2018
- Author(s)
  大澤匡範
- Organizer
  第56回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] Gタンパク質共役型内向き整流性カリウムチャネルのエタノール依存的な活性化機構の解明2018
- Author(s)
  外山侑樹, 加納花穂, 間瀬瑶子, 横川真梨子, 大澤匡範, 嶋田一夫
- Organizer
  第57回NMR討論会
- Data Source
  KAKENHI-PROJECT-18K06606
[Presentation] 溶液NMR 法によるMg2+ チャネルMgtE の開閉機構の解明2018
- Author(s)
  大澤匡範
- Organizer
  大阪大学蛋白質研究所セミナー
- Data Source
  KAKENHI-PUBLICLY-18H04679
[Presentation] Structural dynamics of potassium ion channels revealed by side-chain methyl13C-1H multiple quantum relaxation analyses.2018
- Author(s)
  Yuki Toyama, Hanaho Kano, Yoko Mase, Mariko Yokogawa, Masanori Osawa and Ichio Shimada.
- Organizer
  59th Experimental Nuclear Magnetic Resonance Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04679
[Presentation] 電位依存性カリウムイオンチャネルの膜電位依存的構造変化機構の解明2018
- Author(s)
  藤田浩平，横川真梨子，上和田遥平，日向寺孝禎，野崎智裕，嶋田一夫，大澤匡範
- Organizer
  第2回慶應ライフサイエンスシンポジウム
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] 電位依存性カリウムイオンチャネルhERGの閉状態の安定化による、hERG開閉機構の構造生物学的解明2018
- Author(s)
  松村一輝、簗瀬尚美、秋元まどか、岩崎菜々美、坂本多穗、黒川洵子、横川真梨子、大澤匡範
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] B型肝炎ウイルスの粒子形成機構の解明2018
- Author(s)
  横川真梨子、石場智彬、池田寿子、藤田浩平、横田旭美、大澤匡範
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] Functional roles of Mg2+ binding sites in ion-dependent gating of a Mg2+ channel, MgtE, revealed by solution NMR2018
- Author(s)
  丸山達朗 , 今井駿輔 , 草木迫司 , 服部素之 , 石谷隆一郎 , 濡木理 , 伊藤耕一 , Maturana Andres D. , 嶋田一夫 , 大澤匡範
- Organizer
  第57回NMR討論会
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] B型肝炎ウイルスの粒子形成機構の解明2017
- Author(s)
  横川真梨子、石場智彬、池田寿子、藤田浩平、横田旭美、大澤匡範
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] B型肝炎ウイルスの粒子形成機構の解明2017
- Author(s)
  横川真梨子、石場智彬、池田寿子、藤田浩平、横田旭美、大澤匡範
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] 電位依存性プロトンチャネルVSOP/Hv1のアラキドン酸による活性化促進機構の解明2017
- Author(s)
  松葉広昭、横川真梨子、木村友美、望月綾野、川鍋陽、岡村康司、嶋田一夫、大澤匡範
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] Structural mechanism underlying the millisecond gating of K+ channel2017
- Author(s)
  Yuta Iwahashi, Yuki Toyama, Shunsuke Imai, Masanori Osawa, Ichio Shimada
- Organizer
  58th Experimental Nuclear Magnetic Resonance Conference
- Place of Presentation
  Asilomar Conference Grounds, Pacific Grove, California, USA
- Year and Date
  2017-03-26
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] 電位依存性プロトンチャネルVSOP/Hv1のアラキドン酸による活性化促進機構の解明2017
- Author(s)
  松葉広昭、横川真梨子、木村友美、望月綾野、川鍋陽、岡村康司、嶋田一夫、大澤匡範
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] 緩和速度の磁場依存性解析によるGタンパク質へのGDP結合の動的制御機構の解明2017
- Author(s)
  外山侑樹, 加納花穂, 間瀬瑶子, 横川真梨子, 大澤　匡範, 嶋田　一夫
- Organizer
  第56回NMR討論会
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] Development of Structure-free Design and Analysis for Compound Libraries Based on Chemical and Bioactive Diversity2017
- Author(s)
  Yugo Shimizu, Kazuyoshi Ikeda, Masanori Osawa
- Organizer
  CBI学会
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] Development of structure-free analysis for compound libraries based on chemical and bioactive diversity2017
- Author(s)
  Yugo Shimizu, Kazuyoshi Ikeda, Masanori Osawa
- Organizer
  CBI学会
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] Dynamic regulation of GDP binding to G proteins revealed by magnetic field-dependent NMR relaxation analyses2017
- Author(s)
  Yuki Toyama, Hanaho Kano, Yoko Mase, Mariko Yokogawa, Masanori Osawa, Ichio Shimada
- Organizer
  58th Experimental Nuclear Magnetic Resonance Conference
- Place of Presentation
  Asilomar Conference Grounds, Pacific Grove, California, USA
- Year and Date
  2017-03-26
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] Dynamic regulation of GDP binding to G proteins revealed by magnetic field-dependent NMR relaxation analyses2017
- Author(s)
  Hanaho Kano, Yuki Toyama, Yoko Mase, Mariko Yokogawa, Masanori Osawa, Ichio Shimada
- Organizer
  2017 Taiwan-Japan Biomedical Symposium on Magnetic Resonance
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] ポリA上のPABP多量体による翻訳調節メカニズムの解明2017
- Author(s)
  沢崎綾一、今井駿輔、横川真梨子、細田直、星野真一、三尾和弘、三尾宗代、嶋田一夫、大澤匡範
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] Dynamic regulation of GDP binding to G proteins revealed by magnetic field-dependent NMR relaxation analyses2017
- Author(s)
  Hanaho Kano, Yuki Toyama, Yoko Mase, Mariko Yokogawa, Masanori Osawa, Ichio Shimada
- Organizer
  2017 Taiwan-Japan Biomedical Symposium on Magnetic Resonance
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] ポリA上のPABP多量体による翻訳調節メカニズムの解明2017
- Author(s)
  沢崎綾一、今井駿輔、横川真梨子、細田直、星野真一、三尾和弘、三尾宗代、嶋田一夫、大澤匡範
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] Gタンパク質のファミリー選択的なK+チャネル活性制御機構の解明2017
- Author(s)
  加納花穂, 外山侑樹, 岩橋優太, 間瀬瑶子, 横川真梨子, 大澤　匡範, 嶋田　一夫
- Organizer
  第17回日本蛋白質科学会年会
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] 生物活性情報に基づく構造非開示での化合物ライブラリー多様性評価法の開発2017
- Author(s)
  清水祐吾、池田和由、大澤匡範
- Organizer
  第45回　構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] Gタンパク質のファミリー選択的なK+チャネル活性制御機構の解明2017
- Author(s)
  加納花穂, 外山侑樹, 岩橋優太, 間瀬瑶子, 横川真梨子, 大澤　匡範, 嶋田　一夫
- Organizer
  第17回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] 緩和速度の磁場依存性解析によるGタンパク質へのGDP結合の動的制御機構の解明2017
- Author(s)
  外山侑樹, 加納花穂, 間瀬瑶子, 横川真梨子, 大澤　匡範, 嶋田　一夫
- Organizer
  第56回NMR討論会
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] カリウムチャネルのミリ秒オーダーの開閉の構造機構の解明2017
- Author(s)
  岩橋優太、外山侑樹、今井駿輔、大澤匡範、嶋田一夫
- Organizer
  第17回日本蛋白質科学会年会
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] カリウムチャネルのミリ秒オーダーの開閉の構造機構の解明2017
- Author(s)
  岩橋優太、外山侑樹、今井駿輔、大澤匡範、嶋田一夫
- Organizer
  第17回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] Structure-Free化合物ライブラリー解析システムの構築と検証2017
- Author(s)
  池田和由、清水祐吾、大澤匡範
- Organizer
  第45回　構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-17H03978
[Presentation] 生物活性情報に基づく構造非開示での化合物ライブラリー多様性評価法の開発2017
- Author(s)
  清水祐吾、池田和由、大澤匡範
- Organizer
  第45回　構造活性相関シンポジウム
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] Structure-Free化合物ライブラリー解析システムの構築と検証2017
- Author(s)
  池田和由、清水祐吾、大澤匡範
- Organizer
  第45回　構造活性相関シンポジウム
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] Structural Characterization of PABP Multimerization on Poly(A) Tail2016
- Author(s)
  Ryoichi Sawazaki, Shunsuke Imai, Mariko Yokogawa, Yoko Usui, Takeru Sagae, Shin-ichi Hoshino, Ichio Shimada, Masanori Osawa
- Organizer
  The 27th International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  京都国際会議場（京都府京都市）
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] Structural Basis for Voltage-Sensing Mechanism of a Voltage-Dependent Potassium Channel2016
- Author(s)
  Tomohiro Nozaki, Shin-ichiro Ozawa, Hitomi Harada, Tomomi Kimura, Masanori Osawa, Ichio Shimada
- Organizer
  The 27th International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  京都国際会議場（京都府京都市）
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] Functional Roles of Mg2+-Binding Sites in Mg2+-Dependent Gating of an Mg2+ Channel, MgtE,Revealed by NMR2016
- Author(s)
  Tatsuro Maruyama, Shunsuke Imai, Motoyuki Hattori, Ryuichiro Ishitani, Osamu Nureki, Ichio Shimada, Masanori Osawa
- Organizer
  The 27th International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  京都国際会議場（京都府京都市）
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] Developments and applications of multiple quantum NMR methods to characterize functional dynamics of high molecular weight proteins2016
- Author(s)
  Yuki Toyama, Hanaho Kano, Yoko Mase, Mariko Yokogawa, Masanori Osawa, Ichio Shimada
- Organizer
  The 54th Annual Meeting of the Biophysical Society of Japan
- Place of Presentation
  つくば国際会議場(茨城県つくば市）
- Year and Date
  2016-11-25
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] Structural basis for the inhibition of voltage-dependent K+ channel by gating modifier toxin2016
- Author(s)
  Shin-ichiro Ozawa, Tomomi Kimura, Tomohiro Nozaki, Hitomi Harada, Ichio Shimada, Masanori Osawa
- Organizer
  International and Interdisciplinary Symposium 2016
- Place of Presentation
  東京医科歯科大学（東京都文京区）
- Year and Date
  2016-07-11
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] Molecular mechanism of the ATP-dependent modulation of the Mg2+ channel MgtE for Mg2+ homeositasis2016
- Author(s)
  Atsuhiro Tomita, Mingfeng Zhang, Hironori Takeda, Fei Jin, Tatsuro Maruyama, Masanori Osawa, Ryuichiro Ishitani, Ichio Shimada, Zhiqiang Yan, Motoyuki Hattori, Osamu Nureki
- Organizer
  The 54th Annual Meeting of the Biophysical Society of Japan
- Place of Presentation
  つくば国際会議場(茨城県つくば市）
- Year and Date
  2016-11-25
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] Structural Basis for the Inhibition of Voltage-dependent K+ Channel by Gating Modifier Toxin2016
- Author(s)
  Shin-ichiro Ozawa, Tomomi Kimura, Tomohiro Nozaki, Hitomi Harada, Ichio Shimada, Masanori Osawa
- Organizer
  The 27th International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  京都国際会議場（京都府京都市）
- Year and Date
  2016-08-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] Structural basis for the inhibition of voltage-dependent K+ channel by gating modifier toxin2016
- Author(s)
  Masanori Osawa, hin-ichiro Ozawa, Tomomi Kimura, Tomohiro Nozaki, Hitomi Harada, Ichio Shimada
- Organizer
  The 42nd Naito Conference
- Place of Presentation
  シャトレーゼガトーキングダム（北海道札幌市）
- Year and Date
  2016-10-04
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] Gating modifier toxinによる電位依存性K+チャネル阻害の構造基盤2016
- Author(s)
  大澤匡範
- Organizer
  第60回日本薬学会関東支部大会
- Place of Presentation
  東京大学（東京都文京区）
- Year and Date
  2016-09-17
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] NMR Method for Characterizing Microsecond-to-Millisecond Chemical Exchanges Utilizing2016
- Author(s)
  Yuki Toyama, Masanori Osawa, Mariko Yokogawa, Ichio Shimada
- Organizer
  The 27th International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  京都国際会議場（京都府京都市）
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] NMR Method for Characterizing Microsecond-to-Millisecond Chemical Exchanges Utilizing Differential Multiple-Quantum Relaxation in High Molecular Weight Protein2016
- Author(s)
  Yuki Toyama, Masanori Osawa, Mariko Yokogawa, Ichio Shimada
- Organizer
  第16回東京大学生命科学シンポジウム
- Place of Presentation
  東京大学（東京都文京区）
- Year and Date
  2016-04-23
- Data Source
  KAKENHI-PUBLICLY-16H01368
[Presentation] 電位依存性カリウムイオンチャネルの膜電位感受機構の解明2014
- Author(s)
  野﨑智裕, 小澤新一郎, 原田瞳, 木村友美, 大澤匡範, 嶋田一夫
- Organizer
  日本薬学会　第134年会
- Place of Presentation
  熊本大学（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-24590048
[Presentation] 電位依存性カリウムイオンチャネルの膜電位感受機構の解明2014
- Author(s)
  野﨑智裕, 小澤新一郎, 原田瞳, 木村友美, 大澤匡範, 嶋田一夫
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学(熊本県熊本市)
- Data Source
  KAKENHI-PUBLICLY-25121707
[Presentation] 電位依存性カリウムイオンチャネルの膜電位感受機構の解明2014
- Author(s)
  野﨑智裕, 小澤新一郎, 原田瞳, 木村友美, 大澤匡範, 嶋田一夫
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本県熊本市
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] イオンチャネルの機能に関連した動的構造2013
- Author(s)
  今井駿輔、大澤匡範、三田建一郎、豊永翔、町山麻子、上田卓見、竹内恒、老木成稔、嶋田一夫
- Organizer
  第35回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  東京大学（東京都文京区）
- Data Source
  KAKENHI-PUBLICLY-25121707
[Presentation] Structurral elucidation of the Mg2+-dependent gating mechanism of a Mg2+ transporter MgtE2013
- Author(s)
  丸山達朗, 今井駿輔, 大澤匡範, 服部素之, 石谷隆一郎, 濡木理, 嶋田一夫
- Organizer
  Nagoya Symposium - Frontiers in Structural Physiology
- Place of Presentation
  愛知県名古屋市
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] イオンチャネルの機能に関連した動的構造2013
- Author(s)
  今井駿輔、大澤匡範、三田建一郎、豊永翔、町山麻子、上田卓見、竹内恒、老木成稔、嶋田一夫
- Organizer
  第35回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  東京大学（東京都文京区）
- Data Source
  KAKENHI-PROJECT-24590048
[Presentation] Structural Basis for Regulation of G Protein Regulation of G Protein-activated Inwardly Rectifying Potassium Channel 1 (GIRK1) by G Protein2013
- Author(s)
  大澤匡範、間瀬瑤子、横川真梨子、竹内恒、嶋田一夫
- Organizer
  Nagoya Symposium - Frontiers in Structural Physiology
- Place of Presentation
  愛知県名古屋市
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] イオンチャネルの機能に関連した動的構造2013
- Author(s)
  今井駿輔、○大澤匡範、三田建一郎、豊永翔、町山麻子、上田卓見、竹内恒、老木成稔、嶋田一夫
- Organizer
  第35回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  東京都文京区
- Invited
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] Structural basis for the modulation of the gating property of G protein-gated inwardly rectifying potassium ion channel (GIRK) by G protein α subunit in the i/o-family (Gαi/o)2012
- Author(s)
  間瀬瑤子、横川真梨子、大澤匡範、嶋田一夫
- Organizer
  25th ICMRBS
- Place of Presentation
  リヨン、フランス
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] ATP effect on Mg2+-dependent gating of a Mg2+ channel MgtE2012
- Author(s)
  丸山達朗, 今井駿輔, 大澤匡範, 服部素之, 石谷隆一郎, 濡木理, 嶋田一夫
- Organizer
  第85回生化学会大会
- Place of Presentation
  福岡県福岡市
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] ATP effect on Mg2+-dependent gating of a Mg2+ channel MgtE2012
- Author(s)
  Maruyama T, Imai S, Osawa M, Hattori M, Ishitani R, Nureki O, Shimada I.
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場(福岡)
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PUBLICLY-23107708
[Presentation] 内向き整流性カリウムチャネル開閉機構の解明2012
- Author(s)
  外山侑樹、大澤匡範、横川真梨子、豊永翔、町山麻子、嶋田一夫
- Organizer
  第12回日本蛋白質科学会
- Place of Presentation
  愛知県名古屋市
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] Structural analyses of the gating mechanism of inwardly rectifying potassium channel2012
- Author(s)
  Y. Toyama, M. Osawa, M. Yokogawa, S. Toyanaga, A, Machiyama, I. Shimada
- Organizer
  第12回　日本蛋白質科学会年会
- Place of Presentation
  名古屋国際会議場　（愛知）
- Year and Date
  2012-06-02
- Data Source
  KAKENHI-PUBLICLY-23107708
[Presentation] Structural basis for modulation of gating property of G protein-gated inwardly rectifying potassium ion channel (GIRK) by i/o-family G protein α subunit (Gαi/o).2012
- Author(s)
  Mase Y, Yokogawa M, Osawa M, Shimada I.
- Organizer
  The XXVth International Conference on Magnetic Resonance
- Place of Presentation
  Lyon　（フランス）
- Year and Date
  2012-08-19
- Data Source
  KAKENHI-PUBLICLY-23107708
[Presentation] Elucidation of the Mg2+-dependent gating mechanism of a Mg2+ transporter MgtE2012
- Author(s)
  丸山達朗, 今井駿輔, 大澤匡範, 服部素之, 石谷隆一郎, 濡木理, 嶋田一夫
- Organizer
  25th ICMRBS
- Place of Presentation
  リヨン、フランス
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] Structural analyses of the gating mechanism of inwardly rectifying potassium channel2012
- Author(s)
  Y. Toyama, M. Osawa, M. Yokogawa, S. Toyanaga, A, Machiyama, I. Shimada
- Organizer
  Program for Young Researcher Symposium in Europe
- Place of Presentation
  Oxford (英国)
- Year and Date
  2012-06-06
- Data Source
  KAKENHI-PUBLICLY-23107708
[Presentation] Structural Elucidation of Mg2+-dependent Gating Mechanism of a Mg2+ Transporter MgtE2012
- Author(s)
  Maruyama T, Imai S, Osawa M, Hattori M, Ishitani R, Nureki O, Shimada I.
- Organizer
  The XXVth International Conference on Magnetic Resonance
- Place of Presentation
  Lyon　（フランス）
- Year and Date
  2012-08-19
- Data Source
  KAKENHI-PUBLICLY-23107708
[Presentation] Structural investigation of voltage-sensing mechanism of voltage-dependent K^+ channels2011
- Author(s)
  原田瞳, 大澤匡範, 小澤新一郎, 木村友美, 野崎智裕, 嶋田一夫
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PUBLICLY-23107708
[Presentation] Structural basis for the inhibition of voltage-dependent potassium (Kv) channels by gating modifier toxins2011
- Author(s)
  小澤新一郎, 大澤匡範, 木村友美, 原田瞳, 野崎智裕, 嶋田一夫
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PUBLICLY-23107708
[Presentation] Structural basis for the inhibition of voltage-dependent potassium (Kv) channels by gating modifier toxins2011
- Author(s)
  小澤新一郎, 大澤匡範, 木村友美, 原田瞳, 野崎智裕, 嶋田一夫
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-21590040
[Presentation] Structural investigation of voltage-sensing mechanism of voltage-dependent K+ channels (ポスター)2011
- Author(s)
  原田瞳#, 大澤匡範, 小澤新一郎#, 木村友美, 野崎智裕*, 嶋田一夫
- Organizer
  第34回日本分子生物学会年会日本分子生物学会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] Structural investigation of voltage-sensing mechanism of voltage-dependent K^+ channels2011
- Author(s)
  原田瞳, 大澤匡範, 小澤新一郎, 木村友美, 野崎智裕, 嶋田一夫
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-21590040
[Presentation] Structural basis for the inhibition of voltage-dependent potassium (Kv) channels by gating modifier toxins (ポスター)2011
- Author(s)
  小澤新一郎#、大澤匡範、木村友美、原田瞳#、野崎智裕*、嶋田一夫
- Organizer
  第34回日本分子生物学会年会日本分子生物学会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] Structural studies onthe interaction of spermine withinwardly rectifying potassium channel2008
- Author(s)
  Osawa M. et.al.
- Organizer
  XXIIIrd International Conference onMagnetic Resonance in BiologicalSystems
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2008-08-24
- Data Source
  KAKENHI-PROJECT-19590037
[Presentation] Structural studies on the interaction of spermine with inwar dly rectifying potassium channel2008
- Author(s)
  Osawa M.
- Organizer
  XXIIIrd International Conference on Magnet ic Resonance in Biological Systems
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2008-08-24
- Data Source
  KAKENHI-PROJECT-20051005
[Presentation] Structura .studies on the interaction of sperrmine with inwardly rectifying potassium channel2008
- Author(s)
  Osawa M.
- Organizer
  XXIIIrd International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2008-08-24
- Data Source
  KAKENHI-PROJECT-19590037
[Presentation] Structural analyses of the gating mechanism of inwardly rectifying potassium channel
- Author(s)
  Toyama Y, Osawa M, Yokogawa M, Shimada I
- Organizer
  International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  Dallas （USA）
- Year and Date
  2014-08-24 – 2014-08-29
- Data Source
  KAKENHI-PUBLICLY-25121707
[Presentation] Gタンパク質三量体によるGタンパク質共役型内向き整流性カリウムチャネル活性制御機構の構造生物学的解明
- Author(s)
  加納花穂, 外山侑樹, 岩橋優太, 間瀬瑶子, 横川真梨子,　大澤　匡範, 嶋田　一夫
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24590048
[Presentation] メチルTROSY法による膜タンパク質の機能調節メカニズムの解明
- Author(s)
  大澤匡範, 今井駿輔, 竹内恒, 嶋田一夫
- Organizer
  NMR討論会
- Place of Presentation
  大阪大学（大阪府吹田市）
- Year and Date
  2014-11-04 – 2014-11-06
- Invited
- Data Source
  KAKENHI-PUBLICLY-25121707
[Presentation] 電位依存性カリウムイオンチャネルの膜電位感受機構の解明
- Author(s)
  野﨑智裕、小澤新一郎、原田瞳、木村友美、大澤匡範、嶋田一夫
- Organizer
  第12回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Place of Presentation
  箱根高原ホテル（神奈川県足柄下郡）
- Year and Date
  2014-07-14 – 2014-07-15
- Data Source
  KAKENHI-PROJECT-24590048
[Presentation] 電位依存性カリウムイオンチャネルの膜電位感受機構の解明
- Author(s)
  野﨑智裕、小澤新一郎、原田瞳、木村友美、大澤匡範、嶋田一夫
- Organizer
  第12回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Place of Presentation
  箱根高原ホテル（神奈川県足柄下郡箱根町）
- Year and Date
  2014-07-14 – 2014-07-15
- Data Source
  KAKENHI-PUBLICLY-25121707
[Presentation] Structural Basis for Regulation of G Protein-activated Inwardly Rectifying Potassium
- Author(s)
  Osawa M, Mase Y, Yokogawa M,Takeuchi K, Shimada I
- Organizer
  日本生生物物理学会年会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2014-09-25 – 2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-24590048
[Presentation] メチルTROSY法による膜タンパク質の機能調節メカニズムの解明
- Author(s)
  大澤匡範, 今井駿輔, 竹内恒, 嶋田一夫
- Organizer
  NMR討論会
- Place of Presentation
  大阪大学（大阪府吹田市）
- Year and Date
  2014-11-04 – 2014-11-06
- Invited
- Data Source
  KAKENHI-PROJECT-24590048
[Presentation] Structural Basis for Regulation of G Protein-activated Inwardly Rectifying Potassium Channel 1 (GIRK1) by G Proteins
- Author(s)
  Osawa M, Mase Y, Yokogawa M,Takeuchi K, Shimada I
- Organizer
  International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  Dallas （USA）
- Year and Date
  2014-08-24 – 2014-08-29
- Invited
- Data Source
  KAKENHI-PROJECT-24590048
[Presentation] Structural analyses of the gating mechanism of inwardly rectifying potassium channel
- Author(s)
  Y. Toyama, M. Osawa, M. Yokogawa, S. Toyanaga, A, Machiyama, I. Shimada
- Organizer
  Program for Young Researcher Symposium in Europe
- Place of Presentation
  Oxford　(英国)
- Data Source
  KAKENHI-PROJECT-24590048
[Presentation] Gタンパク質三量体によるGタンパク質共役型内向き整流性カリウムチャネル活性制御機構の構造生物学的解明
- Author(s)
  加納花穂, 外山侑樹, 岩橋優太, 間瀬瑶子, 横川真梨子,　大澤　匡範, 嶋田　一夫
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PUBLICLY-25121707
[Presentation] Structural analyses of the gating mechanism of inwardly rectifying potassium channel
- Author(s)
  Y. Toyama, M. Osawa, M. Yokogawa, S. Toyanaga, A, Machiyama, I. Shimada
- Organizer
  第12回　日本蛋白質科学会年会
- Place of Presentation
  名古屋国際会議場　（愛知）
- Data Source
  KAKENHI-PROJECT-24590048
[Presentation] Structural Elucidation of Mg2+-dependent Gating Mechanism of a Mg2+ Transporter MgtE
- Author(s)
  T. Maruyama, S. Imai, M. Osawa, M. Hattori, R. Ishitani, O. Nureki, I. Shimada
- Organizer
  The XXVth International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  Lyon　（フランス）
- Data Source
  KAKENHI-PROJECT-24590048
[Presentation] ATP effect on Mg2+-dependent gating of a Mg2+ channel MgtE
- Author(s)
  T. Maruyama, S. Imai, M. Osawa, M. Hattori, R. Ishitani, O. Nureki, I. Shimada
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場(福岡)
- Data Source
  KAKENHI-PROJECT-24590048
[Presentation] Structural Basis for Regulation of G Protein-activated Inwardly Rectifying Potassium Channel 1 (GIRK1) by G Proteins
- Author(s)
  Osawa M, Mase Y, Yokogawa M,Takeuchi K, Shimada I
- Organizer
  International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  Dallas （USA）
- Year and Date
  2014-08-24 – 2014-08-29
- Invited
- Data Source
  KAKENHI-PUBLICLY-25121707
[Presentation] Structural Basis for Regulation of G Protein-activated Inwardly Rectifying Potassium Channel 1 (GIRK1) by G Proteins
- Author(s)
  Osawa M, Mase Y, Yokogawa M,Takeuchi K, Shimada I
- Organizer
  日本生生物物理学会年会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2014-09-25 – 2014-09-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-25121707
[Presentation] Structural analyses of the gating mechanism of inwardly rectifying potassium channel
- Author(s)
  Toyama Y, Osawa M, Yokogawa M, Shimada I
- Organizer
  International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  Dallas （USA）
- Year and Date
  2014-08-24 – 2014-08-29
- Data Source
  KAKENHI-PROJECT-24590048
[Presentation] Structural basis for the modulation of the gating property of G protein-gated inwardly rectifying potassium ion channel (GIRK) by the i/o-family G protein α subunit (Gαi/o)
- Author(s)
  Yoko Mase, Mariko Yokogawa, Masanori Osawa, and Ichio Shimada
- Organizer
  The XXVth International Conference on Magnetic Resonance in Biological Systems (ICMRBS)
- Place of Presentation
  Lyon　（フランス）
- Data Source
  KAKENHI-PROJECT-24590048

1. SHIMADA Ichio (70196476)

# of Collaborated Projects: 8 results

# of Collaborated Products: 65 results
2. Yokogawa Mariko (60648020)

# of Collaborated Projects: 5 results

# of Collaborated Products: 103 results
3. KAINOSHO Masatsune (20137029)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. JEE Jungoo (50381554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. UEDA Takumi (20451859)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
6. NISHIDA Noritaka (50456183)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 秋元まどか (80775304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 石田英子 (70563295)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 伊藤清顕 (50551420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. 宇根瑞穂 (20144826)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. 梅澤一夫 (70114402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 清水祐吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. 神田大輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 下村拓史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 梅沢一夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. 間瀬瑶子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 加藤優

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Osawa Masanori 大澤 匡範

OSAWA Masanori 大澤 匡範

Research Projects

Research Products

Co-Researchers

Mechanism of antagonistic action for intermolecular interactions between etiological biopolymers, and novel strategies for drug discoveryPrincipal Investigator

Principal Investigator

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Review Section

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Elucidation of the mechanism of hepatitis B virus entry and control of infection by entry inhibitors

Principal Investigator

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Review Section

Research Institution

Structural mechanism of voltage-gated ion channels based on the functional structures and their transitionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural basis for the hepatocyte specific entry and replication mechanisms of hapatitis B virus and structural based drug discovery

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

14-3-3タンパク質によるリン酸化シグナル経路の熱力学的・構造生物学的基盤Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural analysis of hepatocyte specific entry and replication mechanism of hepatitis B virus

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

リポクオリティと膜蛋白質の相互作用のＮＭＲ解析法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

抗がん剤トランスポーターの構造と機能発現機構の解明

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional regulation of voltage-gated ion channels targeting the voltage sensorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

リポクオリティと膜蛋白質の相互作用のNMR解析法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

三量体G蛋白質によるイオンチャネル活性化シグナリングの構造基盤Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Voltage-dependent structural changes and functinal mechanism of voltage-dependent ion channelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ＮＭＲによる電位依存性イオンチャネルの動的構造と機能発現機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Osawa Masanori 大澤匡範

OSAWA Masanori 大澤匡範

[Book] Large Protein Complexes Revealed by Solution-State NMR: G Proteins and G Protein-Activated Inwardly Rectifying　Potassium Ion Channel2013