HIRASE Tetsuaki 平瀬徹明

Researcher Number	60363446
Affiliation (based on the past Project Information) *help	2012 – 2013: 独立行政法人国立循環器病研究センター, 研究所, 室長 2011: 独立行政法人国立循環器病研究センター, 分子生物学部, 室長 2007 – 2008: 佐賀大学, 医学部, 助教 2005 – 2006: 佐賀大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Metabolomics Except Principal Investigator Circulatory organs internal medicine / Thoracic surgery / Kidney internal medicine
Keywords	Principal Investigator cvtokine / inflammation / atherosclerosis / cardiovascular disease / サイトカイン / 炎症 / 動脈硬化 / 循環器・高血圧 / AMP deaminase / インスリン抵抗性 / 骨格筋 / amp deaminase … More Except Principal Investigator … More CYP2J2 / mitral regurgitation / less invasive surgery / coronary endothelium / coronary artery bypass grafting / NFκB / 冠動脈バイパス術 / 僧帽弁閉鎖不全 / 低侵襲手術 / 冠動脈内皮 / 心拍動下冠動脈バイパス術 / diabetes mellitus / kidney disease / 糖尿病 / 腎臓病 / endothelial cell / atherosclerosis / endothelial function / 脂質 / 循環器・高血圧 / 血管内皮機能 / スタチン / 脂質異常症 / 高脂血症 / 動脈硬化 / 心不全 Less

AMPD1 plays a role in the regulation of insulin sensitivity.Principal Investigator
- Principal Investigator
  
  HIRASE Tetsuaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  National Cardiovascular Center Research Institute
Study of new therapy for heart failure
- Principal Investigator
  
  NODE Koichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Saga University
The role of EET in cardiovascular disease.
- Principal Investigator
  
  NODE Koichi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Saga University
Involvement of WSX-1 in atherosclerosisPrincipal Investigator
- Principal Investigator
  
  HIRASE Tetsuaki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Saga University
Development of CYP2J2 gene therapy for glomeruonephritis and diabetic nephropathy
- Principal Investigator
  
  MIYAZONO Motoaki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Saga University
Analysis of coronary endothelial damage and other adverse effects during off-pump CABG
- Principal Investigator
  
  OKAZAKI Yukio
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Saga University

All 2014 2013 2012 2008 2007 2006 2005 Other

All Journal Article Presentation

[Journal Article] 動脈硬化予防ガイドライン2007年版からみた脂質異常症のと.らえ方と治療方針(6)2008
- Author(s)
  平瀬徹明, 野出孝一
- Journal Title
  
  薬局 59・2
  
  Pages: 200-203
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590748
[Journal Article] A guideline for the treatment of dyslipidemia2008
- Author(s)
  Tetsuaki Hirase, Koichi node
- Journal Title
  
  The Journal of Practical Pharmacy 59
  
  Pages: 200-203
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590748
[Journal Article] Xenogenic macrophage immunization reduces atherosclerosis in apolipoprotein E knockout mice2007
- Author(s)
  Yamashita T, Kawashima S, Hirase T, Shinohara M, Takaya T, Sasaki N, Takeda M, Tawa H, Inoue N, Hirata K, Yokoyama M.
- Journal Title
  
  American Journal of Physiology 293
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590748
[Journal Article] Xenogenic macrophage immunization reduces atherosclerosis in apolipoprotein E knockout mice.2007
- Author(s)
  Yamashita T, Kawashima S, Hirase T, Rhinohara M, Takaya T, Sasaki N, Takeda M, Tawa H, Inoue N, Hirata K, Yokoyama M.
- Journal Title
  
  American Journal of Physiology 293
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590748
[Journal Article] Atorvastatin inhibits angiotensin II-induced T-type Ca^<2+> channel expression in endothelial cells2006
- Author(s)
  Wang D, Hirase T, Inoue T, Node K
- Journal Title
  
  Biochemical and Biophysical Research Communications 347
  
  Pages: 394-400
- Data Source
  KAKENHI-PROJECT-17590748
[Journal Article] アンジオテンシンIIの動脈硬化促進作用2006
- Author(s)
  平瀬徹明、野出孝一
- Journal Title
  
  Progress in Medicine 26
  
  Pages: 3135-3137
- Data Source
  KAKENHI-PROJECT-17590748
[Journal Article] 血管内皮細胞と動脈硬化2006
- Author(s)
  平瀬徹明、野出孝一
- Journal Title
  
  循環器科 59
  
  Pages: 21-24
- Data Source
  KAKENHI-PROJECT-17590748
[Journal Article] メタボリックシンドロームにおける動脈硬化予防を目指した薬物治療法の可能性2006
- Author(s)
  平瀬徹明、野出孝一
- Journal Title
  
  医学のあゆみ 217
  
  Pages: 23-26
- Data Source
  KAKENHI-PROJECT-17590748
[Journal Article] 酸化ストレスによる血管内皮機能障害とスタチン2006
- Author(s)
  平瀬徹明、野出孝一
- Journal Title
  
  別冊医学のあゆみ
  
  Pages: 262-264
- Data Source
  KAKENHI-PROJECT-17590748
[Journal Article] Atorvastatin inhibits angiotensin II-induced T-type Ca2+ channel expression in endothelial cells.2006
- Author(s)
  Wang D, Hirase T, Inoue T, Node K.
- Journal Title
  
  Biochem Biophys Res Commun. 347(2)
  
  Pages: 394-400
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590747
[Journal Article] スタチンの心血管保護作用2006
- Author(s)
  平瀬徹明、野出孝一
- Journal Title
  
  医学のあゆみ 218
  
  Pages: 111-113
- Data Source
  KAKENHI-PROJECT-17590748
[Journal Article] Stent-induced neutrophil activation is associated with an oxidative burst in the inflammatory process, leading to neointimal thickening.2005
- Author(s)
  Inoue T, Kato T, Hikichi Y, Hashimoto S, Hirase T, Morooka T, Imoto Y, Takeda Y, Sendo F, Node K.
- Journal Title
  
  Thromb Haemost. 95(1)
  
  Pages: 43-48
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590747
[Journal Article] メタボリックシンドローム包括的治療薬としてのアンジオテンシン受容体阻害薬とスタチン系薬剤2005
- Author(s)
  平瀬徹明, 野出孝一
- Journal Title
  
  メタボリックシンドローム-病態の分子生物学
  
  Pages: 156-160
- Data Source
  KAKENHI-PROJECT-17590748
[Journal Article] Simvastatin stimulates vascular endothelial growth factor production by hypoxia-inducible factor-1α up-regulation in endothelial cells
- Author(s)
  Ai Nishimoto-Hazuku, Tetsuaki Hirase, Noriko Ide, Yuji Ikeda, Koichi Node
- Journal Title
  
  Journal of Cardiovascular Pharmacology (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590748
[Journal Article] Angiotensin II Increases the Expression of IP-l0 and Renin-angiotensin System in Endothelial Cells.
- Author(s)
  Noriko Ide, Tetsuaki Hirase, Al Nishimoto-Hazuku, Yuji Ikeda, Koichi Node
- Journal Title
  
  Hypertension Research (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590748
[Journal Article] Simvastatin stimulates vascular endothelial growth factor production by hypoxia-inducihle factor-la up-regulation in endothelial cells.
- Author(s)
  Ai Nishimoto-Hazuku, Tetsuaki Hirase, Noriko Ide, Yuji Ikeda, Koichi Node
- Journal Title
  
  Journal of Cardiovascular Pharmacology (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590748
[Journal Article] Angiotensin II Increases the Expression of IP-10 and Renin-angiotensin System in Endothelial Cells
- Author(s)
  Noriko Ide, Tetsuaki Hirase, Ai Nishimoto-Hazuku, Yuji Ikeda, Koichi Node
- Journal Title
  
  Hypertension Research (印刷中)
- NAID
  10021936907
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590748
[Presentation] 高脂肪食により誘導されるインスリン抵抗性への糖代謝におけるAMP deaminaseの関与2014
- Author(s)
  平瀬徹明、Andreas Tandelilin、遠山桂子、程継東、森崎裕子、森崎隆幸
- Organizer
  第47回日本痛風・核酸代謝学会総会
- Place of Presentation
  神戸
- Year and Date
  2014-02-20
- Data Source
  KAKENHI-PROJECT-23591342
[Presentation]2014
- Author(s)
  Andreas Tandelilin、Tetsuaki Hirase、Keiko Toyama、Jidong Cheng、Hiroko Morisaki、Takayuki Morisaki
- Organizer
  第47回日本痛風・核酸代謝学会総会
- Place of Presentation
  神戸
- Year and Date
  2014-02-20
- Data Source
  KAKENHI-PROJECT-23591342
[Presentation] 糖代謝におけるAMP代謝酵素AMPD3の役割2013
- Author(s)
  平瀬徹明、アンドレアスタンデリリン、遠山桂子、程継東、森崎裕子、森崎隆幸
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2013-12-03
- Data Source
  KAKENHI-PROJECT-23591342
[Presentation] 骨格筋インスリン感受性調節におけるAMP代謝酵素AMPD1の役割2013
- Author(s)
  アンドレアスタンデリリン、平瀬徹明、遠山桂子、程継東、森崎裕子、森崎隆幸
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2013-12-03
- Data Source
  KAKENHI-PROJECT-23591342
[Presentation] AMP deaminase 1(AMPD1)はインスリンシグナルを調節する2013
- Author(s)
  平瀬徹明、遠山桂子、程継東、森崎裕子、森崎隆幸
- Organizer
  第46回日本痛風・核酸代謝学会総会
- Place of Presentation
  東京
- Year and Date
  2013-02-14
- Data Source
  KAKENHI-PROJECT-23591342
[Presentation] AMPD1 plays a role in the regulation of insulin sensitivity2012
- Author(s)
  平瀬徹明、遠山桂子、程継東、森崎裕子、森崎隆幸
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23591342
[Presentation] AMPD1 plays a role in the regulation of insulin sensitivity.2012
- Author(s)
  平瀬　徹明、遠山　桂子、程　継東、森崎　裕子、森崎　隆幸
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23591342
[Presentation] 骨格筋インスリン感受性調節におけるAMP代謝酵素AMPD1の役割
- Author(s)
  アンドレアス　タンデリリン、平瀬　徹明、遠山　桂子、新谷　拓也、程　継東、森崎　裕子、森崎　隆幸
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23591342
[Presentation] 高脂肪食により誘導されるインスリン抵抗性へのAMP deaminaseの関与
- Author(s)
  平瀬　徹明、Andreas Tandelilin、遠山　桂子、程　継東、森崎　裕子、森崎　隆幸
- Organizer
  第47回日本痛風・核酸代謝学会総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23591342
[Presentation] AMPD1 is involved in the regulation of insulin sensitivity
- Author(s)
  Andreas Tandelilin、Tetsuaki Hirase、Keiko Toyama、Jidong Cheng、Hiroko Morisaki、Takayuki Morisaki
- Organizer
  第47回日本痛風・核酸代謝学会総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23591342
[Presentation] 糖代謝におけるAMP代謝酵素AMPD3の役割
- Author(s)
  平瀬　徹明、アンドレアス　タンデリリン、遠山　桂子、新谷　拓也、程　継東、森崎　裕子、森崎　隆幸
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23591342

1. NODE Koichi (80359950)

# of Collaborated Projects: 4 results

# of Collaborated Products: 15 results
2. INOUE Teruo (20168454)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
3. AKASHI Makoto (30398119)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. MORISAKI Takayuki (30174410)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
5. MORISAKI Hiroko (40311451)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
6. YOSHIDA Hiroki (40260715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MIYAZONO Motoaki (70380780)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. IKEDA Yuji (30244023)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ANDO Takashi (40281191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. OKAZAKI Yukio (80203975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ITOH Tsuyoshi (10110496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SATOSHI SAtoshi (20291528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. FURUKAWA Kojiro (90264176)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HIRASE Tetsuaki 平瀬 徹明

Research Projects

Research Products

Co-Researchers

AMPD1 plays a role in the regulation of insulin sensitivity.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of new therapy for heart failure

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of EET in cardiovascular disease.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Involvement of WSX-1 in atherosclerosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of CYP2J2 gene therapy for glomeruonephritis and diabetic nephropathy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of coronary endothelial damage and other adverse effects during off-pump CABG

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 動脈硬化予防ガイドライン2007年版からみた脂質異常症のと.らえ方と治療方針(6)2008

Author(s)

Journal Title

Description

Data Source

[Journal Article] A guideline for the treatment of dyslipidemia2008

Author(s)

Journal Title

Description

Data Source

[Journal Article] Xenogenic macrophage immunization reduces atherosclerosis in apolipoprotein E knockout mice2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Xenogenic macrophage immunization reduces atherosclerosis in apolipoprotein E knockout mice.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Atorvastatin inhibits angiotensin II-induced T-type Ca^<2+> channel expression in endothelial cells2006

Author(s)

Journal Title

Data Source

[Journal Article] アンジオテンシンIIの動脈硬化促進作用2006

Author(s)

Journal Title

Data Source

[Journal Article] 血管内皮細胞と動脈硬化2006

Author(s)

Journal Title

Data Source

[Journal Article] メタボリックシンドロームにおける動脈硬化予防を目指した薬物治療法の可能性2006

Author(s)

Journal Title

Data Source

[Journal Article] 酸化ストレスによる血管内皮機能障害とスタチン2006

Author(s)

Journal Title

Data Source

HIRASE Tetsuaki 平瀬徹明