OGURI Tetsuya 小栗鉄也

… Alternative Names

小栗鉄也オグリテツヤ

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Researcher Number	60363925
Other IDs
Affiliation (Current)	2025: 名古屋市立大学, 医薬学総合研究院(医学), 教授
Affiliation (based on the past Project Information) *help	2024: 名古屋市立大学, 医薬学総合研究院(医学), 教授 2019 – 2022: 名古屋市立大学, 医薬学総合研究院(医学), 教授 2018: 名古屋市立大学, 大学院医学研究科, 教授 2015 – 2017: 名古屋市立大学, 大学院医学研究科, 准教授 2012 – 2015: 名古屋市立大学, 医学(系)研究科(研究院), 准教授 2011: 名古屋市立大学, 医学(系)研究科(研究院), 講師 2004 – 2005: 名古屋市立大学, 大学院・医学研究科, 助手
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Basic Section 50020:Tumor diagnostics and therapeutics-related / Applied pharmacology Except Principal Investigator Respiratory organ internal medicine / Basic Section 48030:Pharmacology-related / Basic Section 53030:Respiratory medicine-related
Keywords	Principal Investigator cross talk / 17β-estradiol / co-activator / HEG-β1 / Cdc25B / 遺伝子多型 / 肺癌 / アミノ酸トランスポーター / SLC7A5 / mTOR … More / LAT1 / MATE / 大腸癌 / オキサリプラチン / OCT6 / シスプラチン / 薬剤トランスポーター / estrogen receptor / mitogen-activated protein kinase pathway / EGF / 細胞周期調節 / neu / Her2 / EGFR / TGF-β1 / 蛋白発現誘 / ホルモン不応性 / エストロゲンレセプター / MAPKシグナル経路 / 発現誘導 / Thymidylate synthase / Pemetrexed / Lung cancer / methotrexate / pemetrexed / ABCC11 / 予測バイオマーカー / thymidylate synthase / ABCトランスポーター / ペメトレキシド … More Except Principal Investigator 肺癌 / ネスチン / 小細胞肺癌 / ABCトランスポーター / 一塩基多型 / EGFR遺伝子異常 / 分子標的薬 / 抗癌剤耐性 / 分子標的 / 好中球 / 好酸球 / 遺伝子多型 / 予後 / 咳受容体感受性 / 気道過敏性 / 好酸球性炎症 / 典型的喘息 / 慢性咳嗽 / 咳喘息 Less

薬理学的アプローチによる肺癌の分子標的治療の有効性と耐性化メカニズムの解明
- Principal Investigator
  
  上村剛大
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Nagoya City University
The significance of the amino acid transporter as a cancer therapeutic targets as well as therapeutic effect predictive markerPrincipal Investigator
- Principal Investigator
  
  Tetsuya Oguri
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Nagoya City University
Development of nestin-based therapeutic strategy for overcoming anticancer drug resistance in small cell lung cancer
- Principal Investigator
  
  Maeno Ken
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nagoya City University
Translational research of organic cation transporter as the predictive biomarker for lung cancer chemotherapyPrincipal Investigator
- Principal Investigator
  
  Tetsuya Oguri
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Nagoya City University
Clinical and therapeutic implications of nestin in small cell lung cancer
- Principal Investigator
  
  Maeno Ken
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nagoya City University
Pathophysiology and prognostic factors of classic asthma and cough variant asthma: A comprehensive study
- Principal Investigator
  
  Niimi Akio
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nagoya City University
  Kyoto University
The predictive biomarkers for antifolate anticancer drugsPrincipal Investigator
- Principal Investigator
  
  OGURI Tetsuya
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nagoya City University
The role of Cdc25B in lung cancer progressionPrincipal Investigator
- Principal Investigator
  
  OGURI Tetsuya
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  NAGOYA CITY UNIVERSITY

All 2020 2018 2017 2016 2015 2014 2013 2012 2011

All Journal Article Presentation

[Journal Article] Nestin Expression Affects Resistance to Chemotherapy and Clinical Outcome in Small Cell Lung Cancer2020
- Author(s)
  Sone Kazuki、Maeno Ken、Masaki Ayako、Kunii Eiji、Takakuwa Osamu、Kagawa Yusuke、Takeuchi Akira、Fukuda Satoshi、Uemura Takehiro、Fukumitsu Kensuke、Kanemitsu Yoshihiro、Ohkubo Hirotsugu、Takemura Masaya、Ito Yutaka、Oguri Tetsuya、Inagaki Hiroshi、Niimi Akio
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 10 Pages: 1367-1367
- DOI
  10.3389/fonc.2020.01367
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08181, KAKENHI-PROJECT-18H02633
[Journal Article] Clinical impact of high serum hepatocyte growth factor in advanced non-small cell lung cancer2017
- Author(s)
  Takahiro Tsuji, Yuichi Sakamori, Hiroaki Ozasa, Yoshitaka Yagi, Hitomi Ajimizu, Yuto Yasuda, Tomoko Funazo, Takashi Nomizo, Hironori Yoshida, Hiroki Nagai, Ken Maeno, Tetsuya Oguri, Toyohiro Hirai and Young Hak Kim
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 42 Pages: 71805-71816
- DOI
  10.18632/oncotarget.17895
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16J03807, KAKENHI-PROJECT-26461193
[Journal Article] Nivolumab-induced asthma in a patient with non-small-cell lung cancer2017
- Author(s)
  Maeno K、Fukuda S、Oguri T、Niimi A
- Journal Title
  
  Ann Oncol.
  
  Volume: 28 Issue: 11 Pages: 2891-2891
- DOI
  10.1093/annonc/mdx455
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461193
[Journal Article] Predictive Role of CYFRA21-1 and CEA for Subsequent Docetaxel in Non-small Cell Lung Cancer Patients2017
- Author(s)
  Sone K, Oguri T, Ito K, Kitamura Y, Inoue Y, Takeuchi A, Fukuda S, Takakuwa O, Maeno K, Asano T, Kanemitsu Y, Ohkubo H, Takemura M, Ito Y, Niimi A
- Journal Title
  
  Anticancer Res.
  
  Volume: 37 Pages: 5125-5131
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461193
[Journal Article] Organic cation transporter 6 directly confers resistance to anticancer platinum drugs2016
- Author(s)
  Oguri T, Kunii E, Fukuda S, Sone K, Uemura T, Takakuwa O, Kanemitsu Y, Ohkubo H, Takemura M, Maeno K, Ito Y, Niimi A.
- Journal Title
  
  Biomed Rep
  
  Volume: 5 Issue: 5 Pages: 639-643
- DOI
  10.3892/br.2016.772
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08593
[Journal Article] ABCB1 polymorphism as a predictive biomarker for amrubicin-induced neutropenia.2014
- Author(s)
  Takakuwa O, Oguri T, Uemura T, Kunii E, Nakao M, Hijikata H, Kawaguchi Y, Ohkubo H, Takemura M, Maeno K, Niimi A.
- Journal Title
  
  Anticancer Res
  
  Volume: 34 Issue: 5 Pages: 3517-3522
- DOI
  10.1007/s00280-015-2723-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591117
[Journal Article] Esophagitis resulting from treatment with crizotinib for anaplastic lymphoma kinase rearrangement-positive lung adenocarcinoma: A case report.2014
- Author(s)
  Takakuwa O, Oguri T, Yokoyama M, Hijikata H, Uemura T, Ohkubo H, Maeno K, Niimi A.
- Journal Title
  
  Mol Clin Oncol
  
  Volume: 2 Pages: 121-123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591117
[Journal Article] Thymidylate synthase gene copy number as a predictive marker for response to pemetrexed treatment of lung adenocarcinoma.2013
- Author(s)
  Kasai D, Ozasa H, Oguri T, Miyazaki M, Uemura T, Takakuwa O, Kunii E, Ohkubo H, Maeno K, Niimi A.
- Journal Title
  
  Anticancer Research
  
  Volume: 33 Pages: 1935-1940
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591156
[Journal Article] Analgesic Effect of Switching From Oral Opioids to a Once-a-Day Fentanyl Citrate Transdermal Patch in Patients With Lung Cancer.2013
- Author(s)
  Takakuwa O, Oguri T, Maeno K, Yokoyama M, Hijikata H, Uemura T, Ozasa H, Ohkubo H, Miyazaki M, Niimi A.
- Journal Title
  
  Am J Hosp Palliat Care.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591117
[Journal Article] Thymidylate Synthase gene copy number as a predictive marker for response to pemetrexed treatment in lung adenocarcinoma2013
- Author(s)
  Kasai D, Ozasa H, Oguri T, Miyazaki M, Uemura T, Takakuwa O, Kunii E, Ohkubo H, Maeno K, Niimi A
- Journal Title
  
  Anticancer Res
  
  Volume: 33 Pages: 1935-1940
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591156
[Journal Article] Transformed lymphoplasmacytic lymphoma involving the main carina: A case report.2013
- Author(s)
  Nakao M, Oguri T, Miyazaki M, Hijikata H, Yokoyama M, Kunii E, Uemura T, Takakuwa O, Ohkubo H, Maeno K, Niimi A.
- Journal Title
  
  Oncol Lett.
  
  Volume: 6 Pages: 4409-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591117
[Journal Article] Thymidylate synthase gene copy number as a predictive marker for response to pemetrexed treatment of lung adenocarcinoma.2013
- Author(s)
  Kasai D, Ozasa H, Oguri T, Miyazaki M, Uemura T, Takakuwa O, Kunii E, Ohkubo H, Maeno K, Niimi A.
- Journal Title
  
  Anticancer Res
  
  Volume: ３３ Pages: 1935-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591117
[Journal Article] Preclinical rationale for synergistic interaction of pemetrexed and cytotoxic nucleoside analogues.2012
- Author(s)
  Oguri-T, Ozasa H, Uemura T, Takakuwa O, Kunii E, Kasai D, Ohkubo H, Miyazaki M, Maeno K, Sato S.
- Journal Title
  
  Oncol Lett
  
  Volume: 4 Issue: 3 Pages: 571-575
- DOI
  10.3892/ol.2012.773
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591156
[Presentation] Expression of nestin affect resistance to chemotherapy and clinical outcome in small cell lung cancer2018
- Author(s)
  Sone K, Maeno K, Kunii E, Takakuwa O, Takeuchi A, Fukuda S, Asano T, Kanemitsu Y, Ohkubo H, Takemura M, Ito Y, Oguri T,　Niimi A
- Organizer
  American Association of Cancer Research Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08181
[Presentation] Expression of nestin affect resistance to chemotherapy and clinical outcome in small cell lung cancer2018
- Author(s)
  Sone K, Maeno K, Kunii E, Takakuwa O, Takeuchi A, Fukuda S, Asano T, Kanemitsu Y, Ohkubo H, Takemura M, Ito Y, Oguri T, Niimi A
- Organizer
  American Association of Cancer Research Annual Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461193
[Presentation] EGFR遺伝子変異陰性あるいは不明進行期肺癌に対するエルロチニブ治療効果予測因子としての腫瘍マーカーの検討2017
- Author(s)
  竹内章, 小栗鉄也, 曽根一輝, 福田悟史, 上村剛大, 金光禎寛, 大久保仁嗣, 高桑修, 竹村昌也, 前野健, 伊藤穣, 中村敦, 新実彰男
- Organizer
  日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-26461193
[Presentation] Expression of organic cation transporter 6 mediates the resistance to anticancer platinum drug cisplatin and oxaliplatin2016
- Author(s)
  Kazuki Sone, Satoshi Fukuda, Tetsuya Oguri, Eiji Kunii, Takehiro Uemura, Osamu Takakuwa, Ken Maeno, Akio Niimi
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県　横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K08593
[Presentation] Organic cation transporter 6 directly confers resistance to anticancer platinum drugs2015
- Author(s)
  小栗鉄也
- Organizer
  ESMO Asia 2015 Congresｓ
- Place of Presentation
  シンガポール
- Year and Date
  2015-12-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08593
[Presentation] Significance of thymidylate synthase copy numbers for resistance to pemetrexed in lung cancer2013
- Author(s)
  Kasai D, Oguri T, Ozasa H, Uemura T, Kunii E, Miyazaki M, Takakuwa O, Ohkubo H, Miyazaki M, Maeno K, Sato S
- Organizer
  103th Annual Meeting of American Association of Cancer Research
- Place of Presentation
  Chicago、USA
- Data Source
  KAKENHI-PROJECT-23591156
[Presentation] A SNP538(G>A) in ABCC11/MRP8 determines sensitivity for antimetabolites.2012
- Author(s)
  Uemura T, Oguri T, Ozasa H, Kasai-D, Kunii E, Miyazaki M, Takakuwa O, Ohkubo H, Miyazaki M, Maeno K, Sato S
- Organizer
  103th Annual Meeting of American Association of Cancer Research
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-23591156
[Presentation] Significance of thymidylate synthase copy numbers for resistance to pemetrexed in lung cancer.2012
- Author(s)
  Kasai-D, Oguri T, Ozasa H, Uemura T, Kunii E, Miyazaki M, Takakuwa O, Ohkubo H, Miyazaki M, Maeno K, Sato S.
- Organizer
  103th Annual Meeting of American Association of Cancer Research
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-23591156
[Presentation] A SNP538(G>A) in ABCC11/MRP8 determines sensitivity for antimetabolites2012
- Author(s)
  Uemura T, Oguri T, Ozasa H, Kasai D, Kunii E, Miyazaki M, Takakuwa O, Ohkubo H, Miyazaki M, Maeno K, Sato S
- Organizer
  103th Annual Meeting of American Association of Cancer Research
- Place of Presentation
  Chicago、USA
- Data Source
  KAKENHI-PROJECT-23591156
[Presentation] Thymidylate synthase gene copy number as a predictive marker for response to pemetrexed treatment in lung adenocarcinoma2012
- Author(s)
  笠井大嗣、小栗鉄也、小笹裕晃、上村剛大、國井英治、高桑修、大久保仁嗣、宮崎幹規、前野健、佐藤滋樹、新実彰男
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591156
[Presentation] Thymidylate synthase gene copy number as a predictive marker for response to pemetrexed treatment in lung adenocarcinoma2012
- Author(s)
  笠井大嗣、小栗鉄也、小笹裕晃、上村剛大、國井英治、高桑修、大久保仁嗣、宮崎幹規、前野健、佐藤滋樹、新実彰男
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ホテルロイトン（札幌）
- Data Source
  KAKENHI-PROJECT-23591156
[Presentation] Pemetrexed 治療効果予測因子としてのTS 遺伝子増幅の有用性についての基礎的検討2011
- Author(s)
  笠井大嗣、小栗鉄也，小笹裕晃，上村剛大，高桑　修，國井英治，大久保久嗣，宮崎幹規，前野　健，中村　敦，佐藤滋樹
- Organizer
  第52回日本肺癌学会
- Place of Presentation
  大阪国際会議場（大阪）
- Data Source
  KAKENHI-PROJECT-23591156
[Presentation] Pemetrexed治療効果予測因子としてのTS遺伝子増幅の有用性についての基礎的検討2011
- Author(s)
  笠井大嗣、小栗鉄也,小笹裕晃,上村剛大,高桑修,國井英治,大久保久嗣,宮崎幹規,前野健,中村敦,佐藤滋樹
- Organizer
  第52回日本肺癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23591156

1. Maeno Ken (10444952)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
2. Niimi Akio (30252513)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. MATSUMOTO Hisako (60359809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. ITO Isao (40447975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 小笹裕晃 (80572015)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 高桑修 (10647332)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 上村剛大 (70611565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KUNII Eiji

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. FUKUDA Satoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. Sone Kazuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

OGURI Tetsuya 小栗 鉄也

小栗 鉄也 オグリ テツヤ

Research Projects

Research Products

Co-Researchers

薬理学的アプローチによる肺癌の分子標的治療の有効性と耐性化メカニズムの解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The significance of the amino acid transporter as a cancer therapeutic targets as well as therapeutic effect predictive markerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of nestin-based therapeutic strategy for overcoming anticancer drug resistance in small cell lung cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Translational research of organic cation transporter as the predictive biomarker for lung cancer chemotherapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clinical and therapeutic implications of nestin in small cell lung cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathophysiology and prognostic factors of classic asthma and cough variant asthma: A comprehensive study

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The predictive biomarkers for antifolate anticancer drugsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of Cdc25B in lung cancer progressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Nestin Expression Affects Resistance to Chemotherapy and Clinical Outcome in Small Cell Lung Cancer2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical impact of high serum hepatocyte growth factor in advanced non-small cell lung cancer2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nivolumab-induced asthma in a patient with non-small-cell lung cancer2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Predictive Role of CYFRA21-1 and CEA for Subsequent Docetaxel in Non-small Cell Lung Cancer Patients2017

Author(s)

Journal Title

Data Source

[Journal Article] Organic cation transporter 6 directly confers resistance to anticancer platinum drugs2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ABCB1 polymorphism as a predictive biomarker for amrubicin-induced neutropenia.2014

Author(s)

Journal Title

OGURI Tetsuya 小栗鉄也

小栗鉄也オグリテツヤ