HABU Noboru 羽生昇

Researcher Number	60365369
Other IDs
Affiliation (based on the past Project Information) *help	2016: 慶應義塾大学, 医学部(信濃町), 共同研究員 2015: 独立行政法人国立病院機構(東京医療センター臨床研究センター), 聴覚・平衡覚研究部, 研究員 2015: 慶應義塾大学, 医学部, 助教 2015: 独立行政法人国立病院機構東京医療センター, 臨床研究センター聴覚平衡覚研究部, 研究員 2013 – 2015: 慶應義塾大学, 医学部, 共同研究員 … More 2014: 独立行政法人国立病院機構(東京医療センター臨床研究センター), 聴覚・平衡覚研究部, 外部研究員 2013: 独立行政法人国立病院機構(東京医療センター臨床研究センター), その他部局等, 平衡覚障害研究室研究員 2012: 独立行政法人国立病院機構(東京医療センター臨床研究センター), その他部局等, その他 2011 – 2012: 慶應義塾大学, 医学部, 助教 2011: 国立病院機構東京医療センター臨床研究センター, 聴覚平衡覚研究部, 研究員 2011: 独立行政法人国立病院機構東京医療センター(臨床研究センター), 聴覚・平衡覚研究部, 研究員 2011: 独立行政法人国立病院機構東京医療センター(臨床研究センター), 聴覚平衡覚研究部, 外部研究員 2010: 独立行政法人国立病院機構(東京医療センター臨床研究センター), 聴覚平衡覚研究部, 外部研究員 2009: 独立行政法人国立病院機構東京医療センター(臨床研究センター), 聴覚・平衡覚研究部, 外部研究員 Less
Review Section/Research Field	Principal Investigator Otorhinolaryngology Except Principal Investigator Otorhinolaryngology
Keywords	Principal Investigator 転移 / 癌 / 国際情報交流 / 癌幹細胞 / 頭頸部癌 Except Principal Investigator 癌幹細胞 / 頭頸部癌 / EMT（上皮間葉転換） / 頸部リンパ節転移 / 多変量解析 … More / Cox2 / E-cadherin / 頭頸部扁平上皮癌 / 転写因子 / 唾液腺癌 / Flt-4 / 間葉上皮転換（MET） / 上皮成長因子 / ヒト乳頭腫ウイルス / 後発性リンパ節転移 / 細胞遊走運動 / 独立予後因子 / 生存率 / 転写抑制因子 / 細胞遊走能 / EMT(上皮間葉転換) / 転移 / 遺伝子 / DNAメチル化 / 頭頸部外科学 / EGFR / 幹細胞 Less

Expression of stem cell markers Oct3/4 and Nanog and its clinical significance in oral tongue squamous cell carcinomaPrincipal Investigator
- Principal Investigator
  
  HABU NOBORU
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Keio University
Control of metastasis and cancer stem-like cell property by inducing MET (mesenchymal-epithelial transition) in head and neck cancer
- Principal Investigator
  
  IMANISHI YORIHISA
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Keio University
  Kyorin University
HPV infection and cancer stem-cell in EGFR target therapy for head and neck cancer
- Principal Investigator
  
  Masato Fujii
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
Association with epithelial-mesenchymal trasition andcancer stem cell in Head and Neck cancerPrincipal Investigator
- Principal Investigator
  
  HABU Noboru
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Keio University
Study to control metastasis of HNSCC by targeting molecular mechanisms leading to epithelial-mesenchymal transition (EMT)
- Principal Investigator
  
  IMANISHI Yorihisa
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Keio University
Cancer stem cell and EGFR target therapy for head and neck cancer
- Principal Investigator
  
  FUJII Masato
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  独立行政法人国立病院機構東京医療センター(臨床研究センター)
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
Hypermethylation of PGP9.5 has an important role in head and neck cancer
- Principal Investigator
  
  TOKUMARU Yutaka
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  独立行政法人国立病院機構東京医療センター(臨床研究センター)
  独立行政法人国立病院機構(東京医療センター臨床研究センター)

All 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] Expression of Oct3/4 and Nanog in the head and neck squamous carcinoma cells and its clinical implications for delyaed neck metastasis in stageⅠ/Ⅱ　oral tongue squamous cell carcinoma2015
- Author(s)
  Noboru Habu
- Journal Title
  
  BMC cancer
  
  Volume: 18 Issue: 1 Pages: 730-730
- DOI
  10.1186/s12885-015-1732-9
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25861587, KAKENHI-PROJECT-24592614, KAKENHI-PROJECT-25462692
[Journal Article] Restoration of E-cadherin expression by selective Cox-2 inhibition and the clinical relevance of the epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma2014
- Author(s)
  Ryoichi Fujii, Yorihisa Imanishi, Katsushi Shibata, Nobuya Sakai, Koji Sakamoto, Seiji Shigetomi, Noboru Habu, Kuninori Otsuka, Yoichiro Sato, Yoshihiro Watanabe, Hiroyuki Ozawa, Toshiki Tomita, Kaori Kameyama, Masato Fujii, and Kaoru Ogawa
- Journal Title
  
  J Exp Clin Cancer Res
  
  Volume: 33 Issue: 1 Pages: 40-40
- DOI
  10.1186/1756-9966-33-40
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25462692
[Journal Article] 頭頸部腺様嚢胞癌の治療成績と臨床病理組織学的予後因子の検討2014
- Author(s)
  重冨征爾，今西順久，下田将之，冨田俊樹，小澤宏之，坂本耕二，藤井良一，羽生　昇，大塚邦憲，山下　拓，藤井正人，小川　郁
- Journal Title
  
  日本耳鼻咽喉科学会会報
  
  Volume: 117 Pages: 658-665
- NAID
  130004543643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462692
[Journal Article] 唾液腺導管癌の予後因子解析とHER-2およびアンドロゲン受容体発現の免疫組織化学的検討2013
- Author(s)
  大塚邦憲，今西順久，羽生　昇，佐藤陽一郎，他
- Journal Title
  
  日本耳鼻咽喉科学会会報
  
  Volume: 116 Pages: 1024-1032
- NAID
  10031201765
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462692
[Journal Article] 経口直達的下咽頭喉頭部分切除術における手技的工夫2013
- Author(s)
  今西順久，羽生　昇，佐藤陽一郎，渡部佳弘，他
- Journal Title
  
  頭頸部外科
  
  Volume: 23 Pages: 181-191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462692
[Journal Article] 舌扁平上皮癌症例の臨床統計学的検討2011
- Author(s)
  坂本耕二,今西順久,冨田俊樹,小澤宏之,田川崇正,藤井良一,重冨征爾,羽生昇,大塚邦憲,山下拓,菅家稔,藤井正人,小川郁
- Journal Title
  
  頭頸部癌
  
  Volume: 37 Pages: 529-535
- NAID
  10030815595
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591917
[Journal Article] Identification of Stem-like Cells in Head and Neck Cancer Cell Lines2010
- Author(s)
  Guangwei Sun, Masato Fujii, Akira Sonoda, Yutaka Tokumaru, Tatsuo Matsunaga, Noboru Habu
- Journal Title
  
  Anticancer Research
  
  Volume: 30
- URL
  http://ar.iiarjournals.org/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592211
[Presentation] Expression of stem cell markers Oct3/4 and Nanog in the head and neck squamous carcinoma cells and its clinical implications for delayed neck metastasis in stage I/II tongue squamous cell carcinoma2016
- Author(s)
  Noboru Habu, Yorihisa Imanishi, Kaori Kameyama, Masayuki Shimoda, Yutaka Tokumaru, Koji Sakamoto, Ryoichi Fujii, Seiji Shigetomi, Kuninori Otsuka, Yoichiro Sato, Yoshihiro Watanabe, Hiroyuki Ozawa, Toshiki Tomita, Masato Fujii, Kaoru Ogawa
- Organizer
  American Association for Cancer Research (AACR) 2016 Annual Meeting
- Place of Presentation
  New Orleans (USA)
- Year and Date
  2016-04-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462692
[Presentation] 咽頭扁平上皮癌におけるCox2-inhibitionとE-cadherin発現制御に関する検討2016
- Author(s)
  渡部佳弘，今西順久，小澤宏之，藤井良一，羽生　昇，佐藤陽一郎，関水真理子，伊藤文展，猪狩雄一，斎藤　真，小川　郁
- Organizer
  第4回南関東頭頸部腫瘍懇話会
- Place of Presentation
  ベルサール新宿グランド（東京都新宿区）
- Year and Date
  2016-03-31
- Data Source
  KAKENHI-PROJECT-25462692
[Presentation] 頭頸部扁平上皮癌における癌幹細胞様細胞マーカーの発現とその臨床的意義に関する検討2016
- Author(s)
  羽生　昇，今西順久，坂本耕二，藤井良一，重冨征爾，大塚邦憲，佐藤陽一郎，渡部佳弘，徳丸　裕，藤井正人，小川　郁
- Organizer
  第22回東大・慶應ジョイントカンファレンス
- Place of Presentation
  興和創薬本社ホール（東京都中央区）
- Year and Date
  2016-02-18
- Data Source
  KAKENHI-PROJECT-25462692
[Presentation] 頭頸部扁平上皮癌における選択的Cox-2阻害によるE-cadherin発現回復とEMT（epithelial-to-mesenchymal transition）の臨床的関連2015
- Author(s)
  藤井良一，今西順久，柴田克志，酒井伸也，坂本耕二，重冨征爾，羽生　昇，大塚邦憲，佐藤陽一郎，渡部佳弘，小澤宏之，冨田俊樹，亀山香織，藤井正人，小川　郁
- Organizer
  2015年度慶應義塾大学医学部耳鼻咽喉科学教室総会講演会
- Place of Presentation
  ベルサール新宿グランド（東京都新宿区）
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-25462692
[Presentation] 頭頸部扁平上皮癌における選択的Cox-2阻害によるE-cadherin発現回復とEMT (epithelial-to-mesenchymal transition)の臨床的関連2015
- Author(s)
  藤井良一，今西順久，柴田克志，酒井伸也，坂本耕二，重冨征爾，羽生　昇，大塚邦憲，佐藤陽一郎，渡部佳弘，小澤宏之，冨田俊樹，亀山香織，藤井正人，小川　郁
- Organizer
  第21回　東大・慶應ジョイントカンファレンス
- Place of Presentation
  東京
- Year and Date
  2015-02-12
- Data Source
  KAKENHI-PROJECT-25462692
[Presentation] Expression of stem cell markers Oct3/4 and Nanog and its clinical implication for delayed neck metastasis in tongue carcinoma2015
- Author(s)
  Noboru Habu
- Organizer
  第７４回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25861587
[Presentation] Expression of stem cell markers Oct3/4 and Nanog and its implications for delayed neck metastasis in tongue carcinoma2015
- Author(s)
  Noboru Habu, Yorihisa Imanishi, Kaori Kameyama, Masayuki Shimoda, Yutaka Tokumaru, Seiji Shigetomi, Hiroyuki Ozawa, Masato Fujii, Kaoru Ogawa
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-25462692
[Presentation] 頭頸部扁平上皮癌における癌幹細胞様細胞の発現とその臨床的意義に関する検討2013
- Author(s)
  羽生　昇
- Organizer
  第５１回日本癌治療学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24592614
[Presentation] 頭頸部扁平上皮癌における癌幹細胞様細胞の存在とmarkerの発現に関する検討2013
- Author(s)
  羽生昇
- Organizer
  第114回日本耳鼻咽喉科学会総会・学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-25861587
[Presentation] 頭頸部扁平上皮癌における癌幹細胞様細胞マーカーの発現とその臨床的意義に関する検討2013
- Author(s)
  羽生昇
- Organizer
  第51回日本癌治療学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25861587
[Presentation] 頭頸部扁平上皮癌における癌幹細胞様細胞の存在とマーカーの発現に関する検討2013
- Author(s)
  羽生　昇
- Organizer
  第114回　日本耳鼻咽喉科学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24592614
[Presentation] 頭頸部扁平上皮癌におけるCox2 inhibitionとE-cadherinおよび転写抑制因子の発現に関する検討2012
- Author(s)
  藤井良一, 今西順久, 柴田克志, 酒井伸也, 坂本耕二, 重冨征爾, 羽生昇, 大塚邦憲, 小川郁
- Organizer
  第50回日本癌治療学会
- Place of Presentation
  横浜
- Year and Date
  2012-10-26
- Data Source
  KAKENHI-PROJECT-22591917
[Presentation] Expressions of stem cell markers Oct3/4 and Nanog and its clinical significance in oral tongue squamous cell markers2012
- Author(s)
  Noboru Habu, Yorihisa Imanishi
- Organizer
  8thinternational conference on Head and Neck Cancer
- Place of Presentation
  Toronto, Canada
- Year and Date
  2012-07-25
- Data Source
  KAKENHI-PROJECT-23791933
[Presentation] 頭頸部扁平上皮癌におけるCox2とE-cadherinおよびその転写抑制因子の発現に関する臨床病理学的検討2012
- Author(s)
  藤井良一, 今西順久, 柴田克志, 酒井伸也, 坂本耕二, 重冨征爾, 羽生昇, 大塚邦憲, 冨田俊樹, 小川郁
- Organizer
  第36回頭頸部癌学会
- Place of Presentation
  島根
- Year and Date
  2012-06-07
- Data Source
  KAKENHI-PROJECT-22591917
[Presentation] Expression of stem cell markers Oct3/4 and Nanog and its clinical significance in oral tongue squamous cell carcinoma2012
- Author(s)
  羽生昇
- Organizer
  8th International Conference on Head and Neck Cancer
- Place of Presentation
  トロント（カナダ）
- Data Source
  KAKENHI-PROJECT-23791933
[Presentation] 頭頸部扁平上皮癌におけるがん幹細胞様細胞の存在とmarkerの発現に関する検討2011
- Author(s)
  羽生昇
- Organizer
  頭頸部癌学会
- Place of Presentation
  ウインク愛知（愛知県）
- Data Source
  KAKENHI-PROJECT-23791933
[Presentation] Expression of stem cell markers Oct3/4 and Nanog and its clinical significance in oral tongue squamous cell carcinoma2011
- Author(s)
  羽生昇
- Organizer
  第70回癌学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21592211
[Presentation] Expression of stem cell markers in Oct3/4 and Nanog and its clinical significance in oral tongue squamous cell carcinoma2011
- Author(s)
  羽生昇
- Organizer
  日本癌学会
- Place of Presentation
  名古屋国際会議場（愛知県）
- Data Source
  KAKENHI-PROJECT-23791933
[Presentation] 頭頸部扁平上皮癌におけるがん幹細胞の存在とmakerの発現に関する検討2011
- Author(s)
  羽生昇今西順久徳丸裕坂本耕二冨田俊樹小川郁藤井正人
- Organizer
  第35回日本頭頸部癌学会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-21592211
[Presentation] 口腔舌扁平上皮癌におけるOct3/4とNanogの発現とその臨床的意義2011
- Author(s)
  羽生昇藤井正人今西順久徳丸裕小川郁
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-21592211
[Presentation] 頭頸部扁平上皮癌における癌幹細胞用細胞の存在とmarkerの発言に関する検討2011
- Author(s)
  羽生昇
- Organizer
  第35回頭頸部癌学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21592211
[Presentation] Expressions of stem cell markers Oct3/4 and Nanog and its clinical significance in oral tongue squamous cell markers2011
- Author(s)
  羽生昇、今西順久、徳丸裕、藤井正人
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-23791933
[Presentation] 頭頸部扁平上皮癌における癌幹細胞様細胞の存在と癌幹細胞マーカーの発現に関する検討2011
- Author(s)
  羽生昇、今西順久、徳丸裕、藤井正人、小川郁
- Organizer
  第35回頭頸部癌学会
- Place of Presentation
  名古屋
- Year and Date
  2011-06-12
- Data Source
  KAKENHI-PROJECT-23791933
[Presentation] 頭頸部扁平上皮癌におけるSP細胞の同定と機能の解明2010
- Author(s)
  羽生昇徳丸裕藤井正人
- Organizer
  第34回日本頭頸部癌学会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-21592211
[Presentation] 頭頸部扁平上皮癌細胞株における上皮成長因子受容体と膜型MMPの相互作用2009
- Author(s)
  羽生昇
- Organizer
  第33回日本頭頸部癌学会
- Place of Presentation
  札幌市
- Year and Date
  2009-06-12
- Data Source
  KAKENHI-PROJECT-21592211
[Presentation] 頭頸部扁平上皮癌細胞株における上皮成長因子受容体と膜型MMPの相互作用2009
- Author(s)
  羽生昇徳丸裕角田晃一矢島陽子藤井正人
- Organizer
  第33回日本頭頸部癌学会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-21592211
[Presentation] 頭頸部扁平上皮癌における癌幹細胞様細胞マーカーの発現とその臨床的意義に関する検討
- Author(s)
  羽生昇，今西順久，他
- Organizer
  第51回日本癌治療学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25462692
[Presentation] 頭頸部扁平上皮癌におけるがん幹細胞様細胞の存在とmarkerの発現に関する検討
- Author(s)
  羽生昇，今西順久，他
- Organizer
  第114回日本耳鼻咽喉科学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-25462692

1. FUJII Masato (70129633)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
2. SUNG Koui (40425773)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. IMANISHI Yorihisa (80255538)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
4. FUJII Ryoichi (30348742)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
5. SHIGETOMI Seiji (30365366)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
6. OOTSUKA Kuninori (40465026)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
7. SATO Yoichiro (40624440)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
8. WATANABE Yoshihiro (30445374)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
9. SAKAMOTO Koji (80338136)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
10. TOKUMARU Yutaka (60245579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 孫廣い

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HABU Noboru 羽生 昇

Research Projects

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Expression of stem cell markers Oct3/4 and Nanog and its clinical significance in oral tongue squamous cell carcinomaPrincipal Investigator

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Control of metastasis and cancer stem-like cell property by inducing MET (mesenchymal-epithelial transition) in head and neck cancer

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HPV infection and cancer stem-cell in EGFR target therapy for head and neck cancer

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Association with epithelial-mesenchymal trasition andcancer stem cell in Head and Neck cancerPrincipal Investigator

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Study to control metastasis of HNSCC by targeting molecular mechanisms leading to epithelial-mesenchymal transition (EMT)

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Cancer stem cell and EGFR target therapy for head and neck cancer

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Hypermethylation of PGP9.5 has an important role in head and neck cancer

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[Journal Article] Expression of Oct3/4 and Nanog in the head and neck squamous carcinoma cells and its clinical implications for delyaed neck metastasis in stageⅠ/Ⅱ oral tongue squamous cell carcinoma2015

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[Journal Article] Restoration of E-cadherin expression by selective Cox-2 inhibition and the clinical relevance of the epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma2014

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[Journal Article] 頭頸部腺様嚢胞癌の治療成績と臨床病理組織学的予後因子の検討2014

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[Journal Article] 唾液腺導管癌の予後因子解析とHER-2およびアンドロゲン受容体発現の免疫組織化学的検討2013

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[Journal Article] 経口直達的下咽頭喉頭部分切除術における手技的工夫2013

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[Journal Article] 舌扁平上皮癌症例の臨床統計学的検討2011

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[Journal Article] Identification of Stem-like Cells in Head and Neck Cancer Cell Lines2010

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HABU Noboru 羽生昇

[Journal Article] Expression of Oct3/4 and Nanog in the head and neck squamous carcinoma cells and its clinical implications for delyaed neck metastasis in stageⅠ/Ⅱ　oral tongue squamous cell carcinoma2015