Kikuchi Jiro 菊池次郎

… Alternative Names

KIKUCHI Jiro 菊池次郎

菊池次朗キクチジロウ

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Researcher Number	60371035
Other IDs
Affiliation (Current)	2025: 自治医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2011 – 2023: 自治医科大学, 医学部, 准教授 2008 – 2010: Jichi Medical University, 医学部, 講師 2007: Jichi Medical University, School of Medicine, Associate Professor 2006: 自治医科大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator Hematology / Basic Section 54010:Hematology and medical oncology-related / Applied pharmacology Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Hematology
Keywords	Principal Investigator 多発性骨髄腫 / 薬剤耐性 / 造血器腫瘍 / エピジェネティクス / 血液腫瘍学 / 1q増多 / FOXM1 / 細胞間相互作用 / CD44 / 髄外増幅 … More / 血液内科学 / 感染 / CD180 / 骨髄微小環境 / Toll様受容体 / 国際情報交流 / ヒストン修飾 / 細胞・組織 / 再生医学 / 発生・分化 … More Except Principal Investigator ゲノム解析 / 転写制御 / 多発性骨髄腫 / Reaenerative medicine / Transcription / Gene / Cancer / 移植・再生医療 / 発現制御 / 遺伝子 / 癌 Less

t(11;14)陽性骨髄腫におけるCyclin D1の転写活性化作用の解明と新規治療への応用
- Principal Investigator
  
  古川雄祐
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Teikyo University of Science & Technology
1q増幅を有する多発性骨髄腫において転写因子FOXM1が予後悪化に働く機序の解明Principal Investigator
- Principal Investigator
  
  菊池次郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Jichi Medical University
Elucidation of the mechanisms of extramedullary disease development and drug resistance in multiple myeloma.Principal Investigator
- Principal Investigator
  
  Kikuchi Jiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Jichi Medical University
Myeloma cells are activated in bone marrow microenvironment by the CD180/MD-1 complex, which senses lipopolysaccharide.Principal Investigator
- Principal Investigator
  
  Kikuchi Jiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
Phosphorylation-mediated EZH2 inactivation promotes drug resistance in multiple myeloma.Principal Investigator
- Principal Investigator
  
  Kikuchi Jiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
Identification of a critical epigenetic mechanism via histone modification in drug resistance of blood cancer cells.Principal Investigator
- Principal Investigator
  
  KIKUCHI Jiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
ヒト末梢血白血球の脱分化による幹細胞の誘導Principal Investigator
- Principal Investigator
  
  菊池次郎
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Jichi Medical University
Elucidation of the de of histone deacetylases (HDACs) in leukemogenesis and its impfication in the treatment of leukemia
- Principal Investigator
  
  FURUKAWA Yusuke
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2008 2007 Other

All Journal Article Presentation

[Journal Article] EMD originates from hyaluronan-induced homophilic interactions of CD44 variant-expressing MM cells under shear stress2023
- Author(s)
  Jiro Kikuchi, Nobuyuki Kodama, Masataka Takeshita, Sho Ikeda, Takahiro Kobayashi, Yoshiaki Kuroda, Michihiro Uchiyama, Naoki Osada, Bjarne Bogen, Hiroshi Yasui, Naoto Takahashi, Akiyoshi Miwa, Yusuke Furukawa
- Journal Title
  
  Blood Adv
  
  Volume: 7 Issue: 4 Pages: 508-524
- DOI
  10.1182/bloodadvances.2022007291
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08761
[Journal Article] Fast in-vitro screening of FLT3-ITD inhibitors using silkworm-baculovirus protein expression system2022
- Author(s)
  Naoki Yamamoto, Jiro Kikuchi, Yusuke Furukawa, Naoya Shibayama
- Journal Title
  
  PLoS One
  
  Volume: 17 Issue: 5 Pages: e0261699-e0261699
- DOI
  10.1371/journal.pone.0261699
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08761
[Journal Article] A suitable anti-myeloma drug to overcome drug resistance in bone marrow microenvironment.2021
- Author(s)
  Kikuchi Jiro, Osada Naoki, Furukawa Yusuke.
- Journal Title
  
  International Journal of Myeloma
  
  Volume: 11 Pages: 7-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08761
[Journal Article] mTOR inhibitors sensitize multiple myeloma cells to venetoclax via IKZF3-and Blimp-1-mediated BCL-2 up-regulation2021
- Author(s)
  Naoki Osada, Jiro Kikuchi, Daisuke Koyama, Yoshiaki Kuroda, Hiroshi Yasui, Joel D Leverson, Yusuke Furukawa
- Journal Title
  
  Haematologica
  
  Volume: 106 Issue: 11 Pages: 3008-3013
- DOI
  10.3324/haematol.2021.278506
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08847, KAKENHI-PROJECT-20K08761
[Journal Article] Autophagic degradation of NOXA underlies stromal cell-mediated resistance to proteasome inhibitors in mantle cell lymphoma2021
- Author(s)
  Kuroda Y, Koyama D, Kikuchi J, Mori S, Ichinohe T, Furukawa Y.
- Journal Title
  
  Leukemia research
  
  Volume: 111 Pages: 106672-106672
- DOI
  10.1016/j.leukres.2021.106672
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08847, KAKENHI-PROJECT-20K08761
[Journal Article] Soluble SLAMF7 Promotes the Growth of Myeloma Cells via Homophilic Interaction with Surface SLAMF7.2020
- Author(s)
  Kikuchi J, Hori M, Iha H, Toyama-Sorimachi N, Hagiwara S, Kuroda Y, Koyama D, Izumi T, Yasui H, Suzuki A, Furukawa Y.
- Journal Title
  
  Leukemia.
  
  Volume: 34 Issue: 1 Pages: 180-195
- DOI
  10.1038/s41375-019-0525-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08847, KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-17K09937, KAKENHI-PROJECT-17K09938, KAKENHI-PROJECT-20K08761, KAKENHI-PLANNED-15H05903
[Journal Article] AMP‐activated protein kinase activation primes cytoplasmic translocation and autophagic degradation of the BCR‐ABL protein in CML cells2020
- Author(s)
  Koyama Daisuke、Kikuchi Jiro、Kuroda Yoshiaki、Ohta Masatsugu、Furukawa Yusuke
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 1 Pages: 194-204
- DOI
  10.1111/cas.14698
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08847, KAKENHI-PROJECT-20K08761
[Journal Article] Bone marrow stromal cell-mediated degradation of CD20 leads to primary rituximab resistance in mantle cell lymphoma2020
- Author(s)
  Kuroda Yoshiaki、Yashima-Abo Akiko、Koyama Daisuke、Kikuchi Jiro、Mori Shigehisa、Ito Shigeki、Furukawa Yusuke
- Journal Title
  
  Leukemia
  
  Volume: in press Issue: 5 Pages: 1506-1510
- DOI
  10.1038/s41375-020-01035-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08847, KAKENHI-PROJECT-20K08761
[Journal Article] Molecular basis of clonal evolution in multiple myeloma2020
- Author(s)
  Furukawa Yusuke、Kikuchi Jiro
- Journal Title
  
  International Journal of Hematology
  
  Volume: 111 Issue: 4 Pages: 496-511
- DOI
  10.1007/s12185-020-02829-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08761
[Journal Article] Conversion of human fibroblasts into multipotent cells by cell-penetrating peptides2019
- Author(s)
  Kikuchi J, Hayashi N, Osada N, Sugitani M, and Furukawa Y.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 518 Issue: 1 Pages: 134-140
- DOI
  10.1016/j.bbrc.2019.08.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09937
[Journal Article] Eradication of central nervous system leukemia of T-cell origin with a brain-permeable LSD1 inhibitor.2019
- Author(s)
  Saito S, Kikuchi J, Koyama D, Sato S, Koyama H, Osada N, Kuroda Y, Akahane K, Inukai T, Umehara T, Furukawa Y.
- Journal Title
  
  Clin Cancer Res
  
  Volume: 25 Issue: 5 Pages: 1601-1611
- DOI
  10.1158/1078-0432.ccr-18-0919
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09937, KAKENHI-PROJECT-17K16193, KAKENHI-PROJECT-17K09938
[Journal Article] Lysine-specific Demethylase 1 Accelerates Oncogenesis in p53 Heterozygous Mice via Transcriptional Repression of the Residual Trp53 Allele.2019
- Author(s)
  Wada, T, Kikuchi, J, Koyama, D, Honda, H, Furukawa, Y.
- Journal Title
  
  Leukemia Res. 2019; 82: 29-32.
  
  Volume: 82 Pages: 29-32
- DOI
  10.1016/j.leukres.2019.05.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08847, KAKENHI-PROJECT-17K09937, KAKENHI-PROJECT-17K09938
[Journal Article] Kinetics of cytokine receptor internalization under steady-state conditions affects growth of neighboring blood cells.2019
- Author(s)
  Nagamachi A, Kikuchi J, Kanai A, Furukawa Y, Inaba T.
- Journal Title
  
  Haematologica
  
  Volume: in press Issue: 7 Pages: 1-14
- DOI
  10.3324/haematol.2019.232959
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02838, KAKENHI-PROJECT-17K09938, KAKENHI-PROJECT-20K08761
[Journal Article] Cell adhesion-induced phosphorylation and inactivation of EZH2 confer drug resistance to acute myeloid leukemia cells.2018
- Author(s)
  Kikuchi J, Kuroda Y, Koyama D, and Furukawa Y.
- Journal Title
  
  Int J Hematol
  
  Volume: 107 Issue: 3 Pages: 383-385
- DOI
  10.1007/s12185-017-2376-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09937, KAKENHI-PROJECT-17K16193, KAKENHI-PROJECT-17K09938
[Journal Article] Myeloma Cells Are Activated in Bone Marrow Microenvironment by the　CD180/MD-1 Complex, Which Senses Lipopolysaccharide.2018
- Author(s)
  Kikuchi J, Kuroda Y, Koyama D, Osada N, Izumi T, Yasui H, Kawase T, Ichinohe T, Furukawa Y.
- Journal Title
  
  Cancer Research
  
  Volume: 78 Issue: 7 Pages: 1766-1778
- DOI
  10.1158/0008-5472.can-17-2446
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16193, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17K09937, KAKENHI-PROJECT-17K09938
[Journal Article] Lysine-specific demethylase 1 inhibitors prevent teratoma development from human induced pluripotent stem cells.2018
- Author(s)
  Osada N, Kikuchi J, Umehara T, Sato S, Urabe M, Abe T, Hayashi N, Sugitani M, Hanazono Y, and Furukawa Y.
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 5 Pages: 6450-6462
- DOI
  10.18632/oncotarget.24030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09937, KAKENHI-PROJECT-16H05089, KAKENHI-PROJECT-17K09938
[Journal Article] Involvement of innate immunity in the expansion of multiple myeloma cells and therapeutic intervention with lenalidomide2018
- Author(s)
  Furukawa Y, Kuroda Y, Kikuchi J.
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 59 Issue: 8 Pages: 1048-1057
- DOI
  10.11406/rinketsu.59.1048
- NAID
  130007472200
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09937, KAKENHI-PROJECT-17K09938
[Journal Article] Anti-leukemic activity of bortezomib and carfilzomib on B-cell precursor ALL with IKZF1 deletion.2017
- Author(s)
  Takahashi K, Inukai T, Imamura T, Yano M, , Nemoto A, Sato H, Huang M, Abe M, Kagami K, Shinohara T, Watanabe A, Somazu S, Oshiro H, Akahane K, Goi K, Kikuchi J, Furukawa Y, Goto H, Minegishi M, Iwamoto S, Sugita K.
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 12 Pages: e0188680-e0188680
- DOI
  10.1371/journal.pone.0188680
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09937, KAKENHI-PROJECT-15K09645
[Journal Article] Epigenetic mechanisms of cell adhesion-mediated drug resistance in multiple myeloma.2016
- Author(s)
  Furukawa Y, Kikuchi J.
- Journal Title
  
  Int. J. Hematol
  
  Volume: 104 Issue: 3 Pages: 281-292
- DOI
  10.1007/s12185-016-2048-5
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461430
[Journal Article] Specific Antileukemic Activity of PD0332991, a CDK4/6 Inhibitor, against Philadelphia Chromosome-Positive Lymphoid Leukemia.2016
- Author(s)
  Nemoto A, Saida S, Kato I, Kikuchi J, Furukawa Y, Maeda Y, Akahane K, Honna-Oshiro H, Goi K, Kagami K, Kimura S, Sato Y, Okabe S, Niwa A, Watanabe K, Nakahata T, Heike T, Sugita K, Inukai T.
- Journal Title
  
  Mol Cancer Ther.
  
  Volume: 15 Issue: 1 Pages: 94-105
- DOI
  10.1158/1535-7163.mct-14-1065
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09645, KAKENHI-PROJECT-26670498, KAKENHI-PROJECT-26461430
[Journal Article] Overexpression of the shortest isoform of histone demethylase LSD1 primes hematopoietic stem cells for malignant transformation.2015
- Author(s)
  Wada T, Koyama D, Kikuchi J, Honda H, Furukawa Y.
- Journal Title
  
  Blood
  
  Volume: 125 Issue: 24 Pages: 3731-3746
- DOI
  10.1182/blood-2014-11-610907
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461430, KAKENHI-PROJECT-15K19557, KAKENHI-PROJECT-26293227
[Journal Article] Molecular Pathogenesis of Multiple Myeloma.2015
- Author(s)
  Furukawa, Y, Kikuchi J.
- Journal Title
  
  Int. J. Clin. Oncol.
  
  Volume: 20 Issue: 3 Pages: 413-422
- DOI
  10.1007/s10147-015-0837-0
- NAID
  40022340491
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461430
[Journal Article] Phosphorylation-mediated EZH2 inactivation promotes drug resistance in multiple myeloma.2015
- Author(s)
  Kikuchi J, Koyama D, Wada T, Izumi T, Hofgaad PO, Bogen B, Furukawa Y.
- Journal Title
  
  J Clin Invest
  
  Volume: 125 Issue: 12 Pages: 4375-4390
- DOI
  10.1172/jci80325
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461430, KAKENHI-PROJECT-15K19557
[Journal Article] Romidepsin overcomes cell adhesion-mediated drug resistance in multiple myeloma cells.2014
- Author(s)
  Sripayap P, Nagai T, Hatano K, Kikuchi J, Furukawa Y, Ozawa K
- Journal Title
  
  Acta Haematologica
  
  Volume: 132 Issue: 1 Pages: 1-4
- DOI
  10.1159/000357213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461435, KAKENHI-PROJECT-26461430
[Journal Article] Suitable drug combination with bortezomib for multiple myeloma under stroma-free conditions and in contact with fibronectin or bone marrow stromal cells.2014
- Author(s)
  Kikuchi J, Koyama D, Mukai YH, and Furukawa Y.
- Journal Title
  
  Int J Hematol
  
  Volume: in press Issue: 6 Pages: 726-736
- DOI
  10.1007/s12185-014-1573-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591405, KAKENHI-PUBLICLY-25118721, KAKENHI-PROJECT-25461434, KAKENHI-PROJECT-26461430
[Journal Article] Proteasome inhibitors exert cytotoxicity and increase chemosensitivity via transcriptional repression of Notch1 in T-cell acute lymphoblastic leukemia.2014
- Author(s)
  Koyama D, Kikuchi J, Hiraoka N, Wada T, Kurosawa H, Chiba S, and Furukawa Y.
- Journal Title
  
  Leukemia
  
  Volume: in press Issue: 6 Pages: 1216-1226
- DOI
  10.1038/leu.2013.366
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591405, KAKENHI-PROJECT-23591549, KAKENHI-PUBLICLY-25118721, KAKENHI-PROJECT-25461434, KAKENHI-PROJECT-26461430
[Journal Article] Arf tumor suppressor disrupts the oncogenic positive feedback loop including c-Myc and DDX5.2014
- Author(s)
  Tago K, Funakoshi-Tago M, Itoh H, Furukawa Y, Kikuchi J, Kato T, Suzuki K, Yanagisawa K
- Journal Title
  
  Oncogene
  
  Volume: 未定 Issue: 3 Pages: 310-318
- DOI
  10.1038/onc.2013.561
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23570166, KAKENHI-PUBLICLY-25118721, KAKENHI-PUBLICLY-25121724, KAKENHI-PROJECT-25293013, KAKENHI-PROJECT-25460073, KAKENHI-PROJECT-25461434, KAKENHI-PROJECT-26440062, KAKENHI-PROJECT-26461430
[Journal Article] Purine analog-like properties of bendamustine underlie rapid activation of DNA damage response and synergic effects with pyrimidine analogues in lymphoid malignancies.2014
- Author(s)
  Hiraoka N, Kikuchi J, Koyama D, Uesawa M, Akutsu M, Wada T, Abe M, Mori S, Nakamura Y, Kano Y, and Furukawa Y.
- Journal Title
  
  PLoS One
  
  Volume: 3
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461430
[Journal Article] HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias.2013
- Author(s)
  Calero-Nieto FJ, Joshi A, Bonadies N, Kinston S, Chan WI, Gudgin E, Pridans C, Landry JR, Kikuchi J, Huntly BJ, and Gottgens B.
- Journal Title
  
  Oncogene
  
  Volume: 32 Pages: 5471-5480
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591405
[Journal Article] Alkylating agents induce histone H3K18 hyperacetylation and potentiate HDAC inhibitor-mediated global histone acetylation and cytotoxicity in mantle cell lymphoma.2013
- Author(s)
  Hiraoka N, Kikuchi J, Koyama D, Wada T, Mori S, Nakamura Y, and Furukawa Y.
- Journal Title
  
  Blood Cancer J
  
  Volume: 3 Issue: 12 Pages: 2169-2169
- DOI
  10.1038/bcj.2013.66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591405
[Journal Article] Homopiperazine derivatives as a novel class of proteasome inhibitors with a unique mode of proteasome binding.2013
- Author(s)
  Kikuchi J, Shibayama N, Yamada S, Wada T, Nobuyoshi M, Izumi T, Akutsu M, Kano Y, Sugiyama K, Ohki M, Park SY, and Furukawa Y.
- Journal Title
  
  PLoS One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591405
[Journal Article] BCR-ABL regulates death receptor expression for TNF-related apoptosis-inducing ligand (TRAIL) in Philadelphia chromosome-positive leukemia.2013
- Author(s)
  Kuroda I, Inukai T, Zhang X, Kikuchi J, Furukawa Y, Nemoto A, Akahane K, Hirose K, Honna-Oshiro H, Goi K, Kagami K, Yagita H, Tauchi T, Maeda Y, Sugita K.
- Journal Title
  
  Oncogene
  
  Volume: 32 Pages: 1670-1681
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591405
[Journal Article] The novel orally active proteasome inhibitor K-7174 exerts anti-myeloma activity in vitro and in vivo by down-regulating the expression of class I histone deacetylases.2013
- Author(s)
  Kikuchi J, Yamada S, Koyama D, Wada T, Nobuyoshi M, Izumi T, Akutsu M, Kano Y, and Furukawa Y.
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Issue: 35 Pages: 25593-25602
- DOI
  10.1074/jbc.m113.480574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591405
[Journal Article] HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias2013
- Author(s)
  Calero-Nieto FJ, Joshi A, Bonadies N, Kinston S, Chan WI, Gudgin E, Pridans C, Landry JR, Kikuchi J, Huntly BJ, and Gottgens B
- Journal Title
  
  Oncogene
  
  Volume: 32
- Data Source
  KAKENHI-PROJECT-23591405
[Journal Article] Homopiperazine Derivatives as a Novel Class of Proteasome Inhibitors with a Unique Mode of Proteasome Binding.2013
- Author(s)
  Kikuchi J.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 4 Pages: e60649-e60649
- DOI
  10.1371/journal.pone.0060649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591047, KAKENHI-PROJECT-23591405, KAKENHI-PROJECT-23791089, KAKENHI-PROJECT-25291016, KAKENHI-PUBLICLY-23118524
[Journal Article] Alkylating agents induce histone H3K18 hyperacetylation and potentiate HDAC inhibitor-mediated global histone acetylation and cytotoxicity in mantle cell lymphoma2013
- Author(s)
  Hiraoka N, Kikuchi J, Koyama D, Wada T, Mori S, Nakamura Y, and Furukawa Y
- Journal Title
  
  Blood Cancer J
  
  Volume: 3
- Data Source
  KAKENHI-PROJECT-23591405
[Journal Article] Romidepsin overcomes cell adhesion-mediated drug resistance in multiple myeloma cells.2013
- Author(s)
  Sripayap P, Nagai T, Noborio-Hatano K, Kikuchi J, Furukawa Y, and Ozawa K.
- Journal Title
  
  Acta Hematol
  
  Volume: 132 Pages: 1-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591405
[Journal Article] The novel orally active proteasome inhibitor K-7174 exerts anti-myeloma activity in vitro and in vivo by down-regulating the expression of class I histone deacetylases2013
- Author(s)
  Kikuchi J, Yamada S, Koyama D, Wada T, Nobuyoshi M, Izumi T, Akutsu M, Kano Y, and Furukawa Y
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Pages: 25593-25602
- Data Source
  KAKENHI-PROJECT-23591405
[Journal Article] BCR-ABL regulates death receptor expression for TNF-related apoptosis-inducing ligand (TRAIL) in Philadelphia chromosome- positive leukemia2013
- Author(s)
  Kuroda I, Inukai T, Zhang X, Kikuchi J, Furukawa Y, Nemoto A, Akahane K, Hirose K, Honna-Oshiro H, Goi K, Kagami K, Yagita H, Tauchi T, Maeda Y, Sugita K
- Journal Title
  
  Oncogene
  
  Volume: 32 Pages: 1670-1681
- Data Source
  KAKENHI-PROJECT-23591405
[Journal Article] Romidepsin overcomes cell adhesion- mediated drug resistance in multiple myeloma cells2013
- Author(s)
  Sripayap P, Nagai T, Noborio-Hatano K, Kikuchi J, Furukawa Y, and Ozawa K
- Journal Title
  
  Acta Hematol
  
  Volume: 132 Pages: 1-4
- Data Source
  KAKENHI-PROJECT-23591405
[Journal Article] Homopiperazine derivatives as a novel class of proteasome inhibitors with a unique mode of proteasome binding2013
- Author(s)
  Kikuchi J, Shibayama N, Yamada S, Wada T, Nobuyoshi M, Izumi T, Akutsu M, Kano Y, Sugiyama K, Ohki M, Park SY, and Furukawa Y
- Journal Title
  
  PLoS One
  
  Volume: 8
- Data Source
  KAKENHI-PROJECT-23591405
[Journal Article] CD43, but not P-selectin Glycoprotein Ligand-1, Functions as an E-Selectin Counter-Receptor in Human Pre-B-Cell Leukemia NALL-12008
- Author(s)
  Nonomura, C., Kikuchi, J., Kiyokawa, N., Ozaki, H., Mitsunaga, K., Ando, H., Kanamori, A., Kannagi, .R., Fujimoto, J., Muroi, K., Furukawa., Y., Nakamura, M
- Journal Title
  
  Cancer Res 68
  
  Pages: 790-799
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591083
[Journal Article] The FLT3 Inhibitor PKC412 Exerts Differential Cell Cycle Effects on Leukemic Cells Depending on the Presence of FLT3 Mutations2008
- Author(s)
  Odgerel, T., Kikuchi, J., Wada, T., Shimizu, R., Futaki, K., Kano, Y., Furukawa., Y
- Journal Title
  
  Oncogene 27
  
  Pages: 3102-3110
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591083
[Journal Article] E2F-6 Suppresses Growth-associated Apoptosis of Human Hematopoietic Progenitor Cells by Counteracting Proapoptotic Activity of E2F-12007
- Author(s)
  Kikuchi, J., et. al.
- Journal Title
  
  Stem Cells 25
  
  Pages: 2439-2447
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591083
[Journal Article] E2F-6 Suppresses Growth-associated Apoptosis of Human Hematopoietic Progenitor Cells by Counteracting Proapoptotic Activity of E2F-12007
- Author(s)
  Kikuchi, J., Shimizu, R., Wada, T., Ando, H., Nakamura, M., Ozawa, K., Furukawa., Y
- Journal Title
  
  Stem Cells 25
  
  Pages: 2439-2447
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591083
[Journal Article] E2F-6 Suppresses Growth-associated Apoptosis of Human Hematopoietic Proge nitor Cells by Counteracting Proapoptotic Activity of E2F-1.2007
- Author(s)
  Kikuchi, J., et. al.
- Journal Title
  
  Stem Cells 25
  
  Pages: 2439-2447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591083
[Presentation] Extramedullary diseases originate from hyaluronan-induced homophilic cell-cell interaction of myeloma cells.2022
- Author(s)
  Jiro Kikuchi, Nobuyuki Kodama, Masataka Takeshita, Tomoko Hishima, Sho Ikeda, Takahiro Kobayashi, Yoshiaki Kuroda, Michihiro Uchiyama, Naoki Osada, Bjarne Bogen, Hiroshi Yasui, Naoto Takahashi, Akiyoshi Miwa, Yusuke Furukawa
- Organizer
  第47回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08761
[Presentation] c-FOS mediates IMiDs resistance acting as a co-activator of IKZF1-target genes in multiple myeloma.2022
- Author(s)
  Naoki Osada, Jiro Kikuchi, Hiroshi Yasui, Sho Ikeda, and Yusuke Furukawa
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08761
[Presentation] Osteoclasts robustly express SLAMF7 and secrete soluble SLAMF72022
- Author(s)
  Hirofumi Tenshin, Takeshi Harada, Yusuke Inoue, Jiro Kikuchi, Asuka Oda, Ryohei Sumitani, Masahiro Oura, Kimiko Sogabe, Tomoko Maruhashi, Mamiko Takahashi, Shiro Fujii, Shingen Nakamura, Hirokazu Miki, Masahiro Hiasa, Jumpei Teramachi, Yusuke Furukawa, Masahiro Abe
- Organizer
  第47回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08761
[Presentation] Extramedullary diseases originate from hyaluronan-induced homophilic interaction of CD44v-expressing myeloma cells2022
- Author(s)
  Jiro Kikuchi, Nobuyuki Kodama, Masataka Takeshita, Tomoko Hishima, Sho Ikeda, Takahiro Kobayashi, Yoshiaki Kuroda, Michihiro Uchiyama, Naoki Osada, Bjarne Bogen, Hiroshi Yasui, Naoto Takahashi, Akiyoshi Miwa, Yusuke Furukawa
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08761
[Presentation] c-FOS mediates IMiDs resistance by acting as a co-activator of IKZF1-target genes in multiple myeloma2022
- Author(s)
  Naoki Osada, Jiro Kikuchi, Hiroshi Yasui, Yusuke Furukawa
- Organizer
  第47回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08761
[Presentation] c-FOS mediates IMiDs resistance acting as a co-activator of IKZF1-target genes in multiple myeloma.2021
- Author(s)
  Osada Naoki, Kikuchi Jiro, Yasui Hiroshi, Furukawa Yusuke.
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08761
[Presentation] Extramedullary diseases originate from hyaluronan-induced homophilic cell-cell interaction of myeloma cells.2021
- Author(s)
  Kikuchi Jiro, Kodama Nobuyuki, Takeshita Masataka, Hijima Tomoko, Ikeda Sho, Kobayashi Takahiro, Kuroda Yoshiaki, Uchiyama Michihiro, Osada Naoki, Koyama Daisuke, Bogen Bjarne, Yasui Hiroshi, Takahashi Naoto, Miwa Akiyoshi, Furukawa Yusuke
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08761
[Presentation] Identification of suitable drugs to be combined with venetoclax for the treatment of multiple myeloma2021
- Author(s)
  Osada Naoki, Kikuchi Jiro, Koyama Daisuke, Kuroda Yoshiaki, Yasui Hiroshi, Leverson JD, Furukawa Yusuke.
- Organizer
  第46回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08761
[Presentation] Extramedullary diseases originate from hyaluronan-induced homophilic cell-cell interaction of myeloma cells.2021
- Author(s)
  Kikuchi Jiro, Kodama Nobuyuki, Takeshita Masataka, Hijima Tomoko, Ikeda Sho, Kobayashi Takahiro, Kuroda Yoshiaki, Uchiyama Michihiro, Osada Naoki, Koyama Daisuke, Bogen Bjarne, Yasui Hiroshi, Takahashi Naoto, Miwa Akiyoshi, Furukawa Yusuke
- Organizer
  第46回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08761
[Presentation] AMP‐activated protein kinase activation primes cytoplasmic translocation and autophagic degradation of the BCR‐ABL protein in CML cells2020
- Author(s)
  Koyama Daisuke、Kikuchi Jiro、Kuroda Yoshiaki、Ohta Masatsugu、Furukawa Yusuke
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08761
[Presentation] Soluble SLAMF7 promotes the growth of myeloma cells via homophilic interaction with surface SLAMF72020
- Author(s)
  Kikuchi Jiro、Hori Mitsuo、Iha Hidekatsu、Toyama-Sorimachi Noriko、Hagiwara Shotaro、Kuroda Yoshiaki、Koyama Daisuke、Izumi Tohru、Yasui Hiroshi、Suzuki Atsushi、Furukawa Yusuke
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08761
[Presentation] Bone marrow stromal cell-mediated degradation of CD20 leads to primary rituximab resistance in mantle cell lymphoma2020
- Author(s)
  Kuroda Yoshiaki、Yashima-Abo Akiko、Koyama Daisuke、Kikuchi Jiro、Mori Shigehisa、Ito Shigeki、Furukawa Yusuke
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08761
[Presentation] Kinetics of cytokine receptor internalization under steady-state conditions affects growth of neighboring blood cells2020
- Author(s)
  Nagamachi Akiko、Kikuchi Jiro、Kanai Akinori、Furukawa Yusuke、Inaba Toshiya
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08761
[Presentation] 骨髄腫細胞間相互作用による薬剤耐性獲得機構の解明2019
- Author(s)
  菊池次郎、長田直希、小山大輔、黒田芳明、安井寛、古川雄祐
- Organizer
  第44回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09937
[Presentation] Toll-like receptor and marrow microenvironment as therapeutic targets in multiple myeloma.2019
- Author(s)
  Kikuchi J, Furukawa Y.
- Organizer
  第81回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09937
[Presentation] Subcellular localization of BCR-ABL is regulated by AMPKα in response to ATP demand in CML cells.2019
- Author(s)
  Koyama D, Kikuchi J, Kuroda Y, Ohta M, Furukawa Y.
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09937
[Presentation] 免疫調節薬はToll様受容体CD180の発現抑制を介して感染をきっかけとした病態の進展を予防する2018
- Author(s)
  菊池次郎、黒田芳明、小山大輔、長田直希、和泉透、安井寛、川瀬孝和、一戸辰夫、古川雄祐
- Organizer
  第43回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09937
[Presentation] Microenvironment-induced autophagy promotes bortezomib resistance in mantle cell lymphoma2017
- Author(s)
  Yoshiaki Kuroda, Daisuke Toyama, Jiro Kikuchi, Yusuke Furukawa
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09937
[Presentation] Modulation of innate immunity as a mechanism of Lenalidomide maintenance for multiple myeloma2017
- Author(s)
  Yusuke Furukawa, Yoshiaki Kuroda, Jiro Kikuchi
- Organizer
  第79回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09937
[Presentation] エピジェネティク機構の解明に基づく侵襲性の低いｉＰＳ細胞腫瘍化抑制法の開発2017
- Author(s)
  長田直希、菊池次郎、齋藤詩緒里、卜部匡司、林仲信、杉谷雅彦、古川雄祐
- Organizer
  第１６回日本再生医療学会総会
- Place of Presentation
  仙台国際センター(宮城県仙台市)
- Year and Date
  2017-03-09
- Data Source
  KAKENHI-PROJECT-26461430
[Presentation] 細胞膜透過性ペプチドによる体細胞の初期化2017
- Author(s)
  菊池次郎、林仲信、杉谷雅彦、長田直希、古川雄祐
- Organizer
  第１６回日本再生医療学会総会
- Place of Presentation
  仙台国際センター(宮城県仙台市)
- Year and Date
  2017-03-09
- Data Source
  KAKENHI-PROJECT-26461430
[Presentation] The Toll-like receptor CD180 pathway mediates infection-triggered progression in multiple myeloma.2017
- Author(s)
  Jiro Kikuchi, Yoshiaki Kuroda, Daisuke Koyama, Naoki Osada, Tohru Izumi, Hiroshi Yasui, Takakazu Kawase, Tatsuo Ichinohe, Yusuke Furukawa
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09937
[Presentation] Toll様受容体CD180を介した多発性骨髄腫の進展機序2017
- Author(s)
  菊池次郎、黒田芳明、小山大輔、長田直希、和泉透、安井寛、川瀬孝和、一戸辰夫、古川雄祐
- Organizer
  第42回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09937
[Presentation] IGF-1R/PI3K/Akt as a critical signal transduction pathway of CAM-DR in multiple myeloma2016
- Author(s)
  Jiro Kikuchi, Daisuke Koyama, Taeko Wada, Tohru Izumi, Peter O Hofgaard, Bjarne Bogen, and Yusuke Furukawa1
- Organizer
  第７８回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26461430
[Presentation] Anti-leukemic activity of Carfilzomib against B-cell precursor ALL2016
- Author(s)
  Kazuya Takahashi, Takeshi Inukai, Meixian Huang, Itaru Kuroda, Kinuko Hirose, Atsushi Waatanabe, Shinpei Somazu, Kumiko Goi, Kaiko Kagami, Masako Abe, Kanji Sugita, Chihiro Tomoyasu, Mio Yano, Toshihiko Imamura, Hajime Hosoi, Jiro Kikuchi, Yusuke Furukawa
- Organizer
  第７８回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26461430
[Presentation] The shortest isoform of LSD1 act at the initial step to form pre-leukemic hematopoietic stem cells.2016
- Author(s)
  Taeko Wada, Daisuke Koyama, Jiro Kikuchi, Hiroaki Honda, Yusuke Furukawa
- Organizer
  第７８回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26461430
[Presentation] Phosphorylation-mediated EZH2 inactivation promotes drug resistance in multiple myeloma.2015
- Author(s)
  Jiro Kikuchi, Daisuke Koyama, Taeko Wada, Tohru Izumi, Peter O Hofgaard, Bjarne Bogen, and Yusuke Furukawa.
- Organizer
  ISEH-44th Annual Scientific meeting
- Place of Presentation
  Kyoto
- Year and Date
  2015-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461430
[Presentation] The shortest form of histone demethylase LSD1 is implicated in leukemogenesis.2015
- Author(s)
  Taeko Wada, Daisuke Koyama, Jiro Kikuchi, Hiroaki Honda, and Yusuke Furukawa.
- Organizer
  第７７回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26461430
[Presentation] Epigenetic mechanisms of cell adhesion mediated drug resistance in multiple myeloma.2015
- Author(s)
  Yusuke Furukawa, Jiro Kikuchi.
- Organizer
  第７７回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-17
- Invited
- Data Source
  KAKENHI-PROJECT-26461430
[Presentation] Overexpression of the shortest isoform of histone demethylase LSD1 primes hematopoietic stem/progenitor cells for malignant transformation.2015
- Author(s)
  Taeko Wada, Daisuke Koyama, Jiro Kikuchi, Hiroaki Honda, and Yusuke Furukawa.
- Organizer
  ISEH-44th Annual Scientific meeting
- Place of Presentation
  Kyoto
- Year and Date
  2015-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461430
[Presentation] Phosphorylation-mediated EZH2 inactivation promotes drug resistance in multiple myeloma.2015
- Author(s)
  Jiro Kikuchi, Daisuke Koyama, Taeko Wada, Tohru Izumi, Peter O Hofgaard, Bjarne Bogen, and Yusuke Furukawa.
- Organizer
  第７７回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26461430
[Presentation] Bortezomib overcomes the cell adhesion mediated drug resistance by down-regulating HDAC expression in multiple myeloma2013
- Author(s)
  Furukawa Y, Kikuchi J
- Organizer
  14^<th> International Myeloma Workshop
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2013-04-03
- Data Source
  KAKENHI-PROJECT-23591405
[Presentation] Homopiperazine derivatives as a novel class of proteasome inhibitors with a unique mode of proteasome binding2013
- Author(s)
  Kikuchi J, Shibayama N, Yamada S, Wada T, Nobuyoshi M, Izumi T, Akutsu M, Kano Y, Sugiyama K, Ohki M, Park SY, and Furukawa Y
- Organizer
  14^<th> International Myeloma Workshop
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2013-04-03
- Data Source
  KAKENHI-PROJECT-23591405
[Presentation] Homopiperazine derivatives as a novel class of proteasome inhibitors with a unique mode of proteasome binding2013
- Author(s)
  Kikuchi J, Shibayama N, Yamada S, Wada T, Nobuyoshi M, Izumi T, Akutsu M, Kano Y, Sugiyama K, Ohki M, Park SY, and Furukawa Y.
- Organizer
  第７５回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591405
[Presentation] Homopiperazine derivatives as a novel class of proteasome inhibitors with a unique mode of proteasome binding2013
- Author(s)
  Kikuchi J, Shibayama N, Yamada S, Wada T, Nobuyoshi M, Izumi T, Akutsu M, Kano Y, Sugiyama K, Ohki M, Park SY, and Furukawa Y
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2013-10-12
- Data Source
  KAKENHI-PROJECT-23591405
[Presentation] Homopiperazine derivatives as a novel class of proteasome inhibitors with a unique mode of proteasome binding2013
- Author(s)
  Kikuchi J, Shibayama N, Yamada S, Wada T, Nobuyoshi M, Izumi T, Akutsu M, Kano Y, Sugiyama K, Ohki M, Park SY, and Furukawa Y.
- Organizer
  14th International Myeloma Workshop
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23591405
[Presentation] Bortezomib overcomes the cell adhesion-mediated drug resistance by down-regulating HDAC expression in multiple myeloma2013
- Author(s)
  Furukawa Y, and Kikuchi J
- Organizer
  14th International Myeloma Workshop
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23591405
[Presentation] EZH2 activation as a novel strategy to overcome cell adhesion mediated-drug resistance in multiple myeloma
- Author(s)
  Jiro Kikuchi, Daisuke Koyama, Taeko Wada, Tohru Izumi, Peter O Hofgaard, Bjarne Bogen, and Yusuke Furukawa,
- Organizer
  第７６回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26461430
[Presentation] 多発性骨髄腫細胞に対するフィブロネクチン及び骨髄間質細胞との接着下におけるボルテゾミブ併用効果
- Author(s)
  菊池次郎、小山大輔、向井陽美、古川雄祐
- Organizer
  第３９回日本骨髄腫学会学術集会
- Place of Presentation
  掛川グランドホテル
- Year and Date
  2014-05-17 – 2014-05-18
- Data Source
  KAKENHI-PROJECT-26461430
[Presentation] The shortest isoform of histone demethylase LSD1 is implicated in leukemogenesis
- Author(s)
  Taeko Wada, Daisuke Koyama, Jiro Kikuchi, Hiroaki Honda and Yusuke Furukawa.
- Organizer
  第７６回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26461430
[Presentation] Proteasome inhibitors exert cytotoxicity and increase chemosensitivity via transcriptional repression of Notch1 in T-cell acute lymphoblastic leukemia.
- Author(s)
  Koyama D, Kikuchi J, Hiraoka N, Wada T, Kurosawa H, Chiba S, and Furukawa Y.
- Organizer
  第７６回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26461430

1. FURUKAWA Yusuke (00199431)

# of Collaborated Projects: 3 results

# of Collaborated Products: 21 results
2. WADA Taeko (30382956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 長田直希 (60840858)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TAGO Kenji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 小山大輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
6. 永井正

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 金井昭教

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 長町安希子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 稲葉俊哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 犬飼岳史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 渡邊敦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kikuchi Jiro 菊池 次郎

KIKUCHI Jiro 菊池 次郎

菊池 次朗 キクチ ジロウ

Research Projects

Research Products

Co-Researchers

t(11;14)陽性骨髄腫におけるCyclin D1の転写活性化作用の解明と新規治療への応用

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

1q増幅を有する多発性骨髄腫において転写因子FOXM1が予後悪化に働く機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanisms of extramedullary disease development and drug resistance in multiple myeloma.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Myeloma cells are activated in bone marrow microenvironment by the CD180/MD-1 complex, which senses lipopolysaccharide.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Phosphorylation-mediated EZH2 inactivation promotes drug resistance in multiple myeloma.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of a critical epigenetic mechanism via histone modification in drug resistance of blood cancer cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒト末梢血白血球の脱分化による幹細胞の誘導Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the de of histone deacetylases (HDACs) in leukemogenesis and its impfication in the treatment of leukemia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] EMD originates from hyaluronan-induced homophilic interactions of CD44 variant-expressing MM cells under shear stress2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fast in-vitro screening of FLT3-ITD inhibitors using silkworm-baculovirus protein expression system2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A suitable anti-myeloma drug to overcome drug resistance in bone marrow microenvironment.2021

Author(s)

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[Journal Article] mTOR inhibitors sensitize multiple myeloma cells to venetoclax via IKZF3-and Blimp-1-mediated BCL-2 up-regulation2021

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[Journal Article] Autophagic degradation of NOXA underlies stromal cell-mediated resistance to proteasome inhibitors in mantle cell lymphoma2021

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[Journal Article] Soluble SLAMF7 Promotes the Growth of Myeloma Cells via Homophilic Interaction with Surface SLAMF7.2020

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Kikuchi Jiro 菊池次郎

KIKUCHI Jiro 菊池次郎

菊池次朗キクチジロウ

[Journal Article] Myeloma Cells Are Activated in Bone Marrow Microenvironment by the　CD180/MD-1 Complex, Which Senses Lipopolysaccharide.2018