sasahara yoji 笹原洋二

… Alternative Names

Sasahara Yoji 笹原洋二

SASAHARA Yoji 笹原洋二

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Researcher Number	60372314
Other IDs
External Links
Affiliation (Current)	2025: 東北大学, 医学系研究科, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2023: 東北大学, 医学系研究科, 准教授 2016 – 2017: 東北大学, 医学系研究科, 准教授 2016: 東北大学, 大学院医学系研究科, 准教授 2014 – 2016: 東北大学, 医学(系)研究科(研究院), 准教授 2011 – 2013: 東北大学, 大学病院, 講師 … More 2008 – 2010: Tohoku University, 病院, 講師 2007: 東北大学, 病院, 助教 2006: Tohoku University, Hospital, Research Associate, 病院・助手 2006: 東北大学, 病院, 助手 2004 – 2005: 東北大学, 加齢医学研究所, 助手 Less
Review Section/Research Field	Principal Investigator Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 54010:Hematology and medical oncology-related Except Principal Investigator Pediatrics / Lifelong developmental nursing
Keywords	Principal Investigator Wiskott-Aldrich症候群 / WIP / WASP / CDC42 / 網羅的遺伝子解析 / 遺伝性血小板減少症 / シグナル伝達 / 原発性免疫不全症 / TLN1 / MECOM … More / トランスレーショナルリサーチ / 血液学 / 遺伝子 / NOGマウス / ヒト化マウス / 免疫学 / マイクロアレイ / 原発性免疫不全症候群 / WAS … More Except Principal Investigator X-SCID / 遺伝子治療 / EBV / B-LCL / γc鎖 / 重症複合免疫不全症 / 細胞障害性T細胞 / 人工抗原提示 / X染色体連鎖性好中球減少症 / WIP欠損症 / WASP恒常的活性化変異 / WIP / WASP / tetoramer / cytotoxic T cells / peptide antigens / 細胞障害活性定量 / フローサイトメーター / CD28抗体 / HLA-A24 / 汎用性人工抗原提示細胞 / 抗原提示細胞 / テトラマー解析 / ペプチド抗原 / suicide gene / gene therapy / γc chain / severe combined immunodeficiency / primary immunodeficiency / 原発生免疫不全症 / 自殺遺伝子 / 原発性免疫不全症 / トランジション / 家族 / 震災 / 小児がん / 看護学 / transition / 動物モデル / 先天性免疫不全症 / 挿入変異 / レトロウィルスベクター / セカンドヒット / k-ras / 白血病 / AF10 / MLL / LMO2 / レトロウイルスベクター / NOGマウス / キメラ二重鎖切断酵素 / HSVtk / 二重鎖切断酵素 / 人工抗原提示細胞 / 神経芽細胞腫 Less

Prpposal of novel inherited thrombocytopenias by clarifying molecular pathogenesis of cytoskeletal signaling and hematopoiesis.Principal Investigator
- Principal Investigator
  
  笹原洋二
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Tohoku University
Establishment of comprehensive genetic analysis and proposal of novel disease entities in inherited thrombocytopenias.Principal Investigator
- Principal Investigator
  
  Sasahara Yoji
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Tohoku University
How to support compiled transition childhood survivors and their families have experienced
- Principal Investigator
  
  Kamibeppu Kiyoko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Lifelong developmental nursing
- Research Institution
  The University of Tokyo
Responsible genes and molecular pathogenesis of inherited thrombocytopenia with small or normal-sized plateletsPrincipal Investigator
- Principal Investigator
  
  SASAHARA Yoji
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Tohoku University
The open conformation of WASP regulates its nuclear localization and gene transcription in myeloid cells
- Principal Investigator
  
  WATANABE YUKO
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Tohoku University
Study on molecular pathogenesis of X-linked neutropenia and WIP deficiency by using NOG mice and human myeloid cell line.Principal Investigator
- Principal Investigator
  
  SASAHARA Yoji
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Tohoku University
Clinical significance of WASP protein complex in nucleus.Principal Investigator
- Principal Investigator
  
  SASAHARA Yoji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Tohoku University
Leukemogenesis due to insertional mutagenesis-a NOG mouse model-
- Principal Investigator
  
  TSUCHIYA Shigeru
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Tohoku University
X連鎖重症複合免疫不全症に対するキメラ二重鎖切断酵素を利用した遺伝子治療法の開発
- Principal Investigator
  
  KUMAKI Satoru
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Tohoku University
神経芽腫腫瘍抗原に対する人工免疫グロブリンレセプターを利用した新規免疫療法の開発
- Principal Investigator
  
  TSUCHIYA Shigeru
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Tohoku University
Wiskott-Aldrich症候群の分子病態の解明とType2-WASの提唱Principal Investigator
- Principal Investigator
  
  笹原洋二
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Pediatrics
- Research Institution
  Tohoku University
Induction of human cytotoxic T cells by peptide-pulsed universal antigen presenting cells
- Principal Investigator
  
  TSUCHIYA Shigeru
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Tohoku University
Development of new and safer gene therapy method for severe combined immunodeficiency.
- Principal Investigator
  
  KUMAKI Satoru
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Tohoku University

[Book] 臨床免疫・アレルギー科　CDC42が誘導するインフラマソームの新たな炎症誘導機構2023
- Author(s)
  笹原洋二
- Total Pages
  5
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-23K07286
[Book] 別冊　日本臨牀　血液症候群（第3版）Ⅱ　ーその他の血液疾患を含めてー　Wiskott-Aldrich症候群2023
- Author(s)
  笹原洋二
- Total Pages
  6
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-23K07286
[Book] 血液専門医テキスト（改訂第4版）　先天性血小板減少症・機能異常症2023
- Author(s)
  笹原洋二
- Total Pages
  4
- Publisher
  南江堂
- ISBN
  9784524203710
- Data Source
  KAKENHI-PROJECT-23K07286
[Book] 原発性免疫不全症候群　診療の手引き（改訂第2版）　ウィスコット・オルドリッチ（Wiskott-Aldrich症候群）（WAS）2023
- Author(s)
  笹原洋二
- Total Pages
  6
- Publisher
  診断と治療社
- ISBN
  9784787826305
- Data Source
  KAKENHI-PROJECT-23K07286
[Book] ITP　小児科診療ガイドライン-最新の診療指針-第5版2022
- Author(s)
  笹原洋二
- Total Pages
  5
- Publisher
  総合医学社
- ISBN
  9784883784707
- Data Source
  KAKENHI-PROJECT-19K08855
[Book] 小児免疫性血小板減少症診療ガイドライン2022年度版2022
- Author(s)
  石黒精、森麻希子、宮川義隆、今泉益栄、小林尚明、笹原洋二、内山徹、高橋幸博、東川正宗、日本小児血液・がん学会血小板委員会
- Total Pages
  91
- Publisher
  診断と治療社
- ISBN
  9784787825544
- Data Source
  KAKENHI-PROJECT-19K08855
[Journal Article] Reduced-intensity conditioning is effective for allogeneic hematopoietic stem cell transplantation in infants with MECOM-associated syndrome2022
- Author(s)
  Irie Masahiro、Katayama Saori、Moriya Kunihiko、Niizuma Hidetaka、Suzuki Nobu、Saito-Nanjo Yuka、Onuma MasaeiIkeda Junji、Kato Motohiro、Takita Junko、Maeda Miho、Aoki Yoko、Imaizumi Masue、Sasahara Yoji
- Journal Title
  
  International Journal of Hematology
  
  Volume: 117 Issue: 4 Pages: 598-606
- DOI
  10.1007/s12185-022-03505-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07791, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-20H03637, KAKENHI-PROJECT-19K08855, KAKENHI-PROJECT-21K19405, KAKENHI-PROJECT-23K07286
[Journal Article] Trapping of CDC42 C-terminal variants in the Golgi drives pyrin inflammasome hyperactivation2022
- Author(s)
  Nishitani-Isa M, Mukai K, Honda Y, Nihira H, Tanaka T, Shibata H, Miyamoto T, Komada K, Hiejima E, Izawa K, Kawasaki Y, Osawa M, Katata Y, Onodera S, Watanabe T, Kure S, Takita J, Ohara O, Saito M, Nishikomori R, Taguchi T, Sasahara Y#, Yasuki T#. (# Equal corresponding author)
- Journal Title
  
  J Exp Med
  
  Volume: 219(6) Issue: 6
- DOI
  10.1084/jem.20211889
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08855, KAKENHI-PROJECT-22K07829, KAKENHI-PROJECT-22K15919, KAKENHI-PROJECT-20H03202
[Journal Article] Phenotypic heterogeneity in individuals with MECOM variants in 2 families.2022
- Author(s)
  Niihori T, Tanoshima R, Sasahara Y, Sato A, Irie M, Saito-Nanjo Y, Funayama R, Shirota M, Abe T, Okuyama Y, Ishii N, Nakayama K, Kure S, Imaizumi M, Aoki Y.
- Journal Title
  
  Blood Adv.
  
  Volume: - Issue: 18 Pages: 5257-5261
- DOI
  10.1182/bloodadvances.2020003812
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03637, KAKENHI-PROJECT-21H02458, KAKENHI-PROJECT-19K08855, KAKENHI-PROJECT-20K07546, KAKENHI-PROJECT-20K08766
[Journal Article] 小児免疫性血小板減少症診療ガイドライン2022
- Author(s)
  石黒精、森麻希子、宮川義隆、今泉益栄、小林尚明、笹原洋二、内山徹、野村理、堀内清華、高橋幸博、東川正宗、日本小児血液・がん学会血小板委員会
- Journal Title
  
  日本小児血液・がん学会雑誌
  
  Volume: 159(1) Pages: 50-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08855
[Journal Article] Impairment of cytokine production following immunological synapse formation in patients with Wiskott-Aldrich syndrome and leukocyte adhesion deficiency type 1.2022
- Author(s)
  Sasahara Y, Wada T, Morio T.
- Journal Title
  
  Clin Immunol
  
  Volume: 242 Pages: 109098-109098
- DOI
  10.1016/j.clim.2022.109098
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08855
[Journal Article] 総説　先天性血小板減少症・異常症の診療ガイド2021
- Author(s)
  笹原洋二、國島伸治、石黒精、日本小児血液・がん学会血小板委員会
- Journal Title
  
  日本小児血液・がん学会雑誌
  
  Volume: 58(3) Pages: 253-262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08855
[Journal Article] 総説　先天性血小板減少症・異常症2021
- Author(s)
  笹原洋二
- Journal Title
  
  臨床血液　日本血液学会雑誌
  
  Volume: 62(8) Pages: 1319-1326
- Data Source
  KAKENHI-PROJECT-19K08855
[Journal Article] Wiskott-Aldrich（ウイスコット・オルドリッチ）症候群2020
- Author(s)
  笹原洋二
- Journal Title
  
  小児感染免疫学
  
  Volume: － Pages: 628-632
- Data Source
  KAKENHI-PROJECT-19K08855
[Journal Article] ARPC1B欠損症2020
- Author(s)
  笹原洋二
- Journal Title
  
  原発性免疫不全症候群―最新の疾患分類と新規疾患を中心にー
  
  Volume: － Pages: 93-95
- Data Source
  KAKENHI-PROJECT-19K08855
[Journal Article] Wiskott-Aldrich症候群2020
- Author(s)
  笹原洋二
- Journal Title
  
  新臨床内科学
  
  Volume: － Pages: 1806-1807
- Data Source
  KAKENHI-PROJECT-19K08855
[Journal Article] 免疫系以外の症状を呈する、あるいは症候群を呈する複合免疫不全症　概念及びトピックス2020
- Author(s)
  笹原洋二
- Journal Title
  
  原発性免疫不全症候群―最新の疾患分類と新規疾患を中心にー
  
  Volume: － Pages: 87-92
- Data Source
  KAKENHI-PROJECT-19K08855
[Journal Article] 免疫性血小板減少性紫斑病2020
- Author(s)
  笹原洋二
- Journal Title
  
  今日の小児治療指針
  
  Volume: － Pages: 550-551
- Data Source
  KAKENHI-PROJECT-19K08855
[Journal Article] 免疫不全症にみられる悪性腫瘍の特徴2019
- Author(s)
  笹原洋二
- Journal Title
  
  小児科診療
  
  Volume: 83 Pages: 341-344
- Data Source
  KAKENHI-PROJECT-19K08855
[Journal Article] Wiskott-Aldrich症候群に合併した全身性自己免疫性炎症にRituximabが奏効した一例2019
- Author(s)
  中野智太、新妻秀剛、片山紗乙莉、渡辺祐子、入江正寛、力石健、笹原洋二、呉繁夫
- Journal Title
  
  日本小児血液・がん学会雑誌
  
  Volume: 56 Pages: 221-224
- NAID
  130007705321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08855
[Journal Article] 総説：単一血球減少と小児がんを合併する原発性免疫不全症2017
- Author(s)
  笹原洋二
- Journal Title
  
  日本小児血液・がん学会雑誌
  
  Volume: 54（2） Pages: 101-105
- Data Source
  KAKENHI-PROJECT-26461562
[Journal Article] Wiskott-Aldrich症候群2016
- Author(s)
  笹原洋二
- Journal Title
  
  日本臨牀　免疫症候群Ⅲ　第2版
  
  Volume: 36 Pages: 179-182
- Data Source
  KAKENHI-PROJECT-26461562
[Journal Article] WIP欠損症2016
- Author(s)
  笹原洋二
- Journal Title
  
  日本臨牀　免疫症候群Ⅲ　第2版
  
  Volume: 36 Pages: 183-186
- Data Source
  KAKENHI-PROJECT-26461562
[Journal Article] The WASP-WIP complex in the molecular pathogenesis of Wiskott-Aldrich syndrome.2016
- Author(s)
  Sasahara Y.
- Journal Title
  
  Pediatr. Int.
  
  Volume: 58(1) Issue: 1 Pages: 4-7
- DOI
  10.1111/ped.12819
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461562
[Journal Article] TAR症候群（thrombocytopenia with absent radius症候群）2016
- Author(s)
  笹原洋二
- Journal Title
  
  小児科診療
  
  Volume: 79 Pages: 191-191
- Data Source
  KAKENHI-PROJECT-26461562
[Journal Article] Wiskott-Aldrich症候群の分子病態に関する研究2016
- Author(s)
  笹原洋二
- Journal Title
  
  東北医学雑誌
  
  Volume: 128 Pages: 52-53
- Data Source
  KAKENHI-PROJECT-26461562
[Journal Article] 遺伝性血小板減少症2016
- Author(s)
  笹原洋二
- Journal Title
  
  小児内科
  
  Volume: 48 Pages: 1026-1031
- Data Source
  KAKENHI-PROJECT-26461562
[Journal Article] 総説：ITPと鑑別が必要な小型・正常大の血小板を有する遺伝性血小板減少症2015
- Author(s)
  笹原洋二
- Journal Title
  
  日本小児血液・がん学会雑誌
  
  Volume: 52(3) Pages: 311-316
- Data Source
  KAKENHI-PROJECT-26461562
[Journal Article] Analyses of genetic and clinical parameters for screening patients with inherited thrombocytopenia with small or normal-sized platelets.2015
- Author(s)
  Ouchi-Uchiyama M, Sasahara Y, Kikuchi A, Goi K, Nakane T, Ikeno M, Noguchi Y, Uike N, Miyajima Y, Matsubara K, Koh K, Sugita K, Imaizumi M, Kure S.
- Journal Title
  
  Pediatr. Blood & Cancer
  
  Volume: 62(12) Issue: 12 Pages: 2082-2088
- DOI
  10.1002/pbc.25668
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461562
[Journal Article] Mutations in MECOM, Encoding Oncoprotein EVI1, Cause Radioulnar Synostosis with Amegakaryocytic Thrombocytopenia.2015
- Author(s)
  Niihori T, Ouchi-Uchiyama M, Sasahara Y, Kaneko T, Hashii Y, Irie M, Sato A, Saito-Nanjo Y, Funayama R, Nagashima T, Inoue S, Nakayama K, Ozono K, Kure S, Matsubara Y, Imaizumi M, Aoki Y.
- Journal Title
  
  Am J Hum Genet.
  
  Volume: 97 Issue: 6 Pages: 848-854
- DOI
  10.1016/j.ajhg.2015.10.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461520, KAKENHI-PROJECT-26461562, KAKENHI-PROJECT-26830064
[Journal Article] Wiskott-Aldrich症候群2015
- Author(s)
  笹原洋二
- Journal Title
  
  小児内科　小児疾患診療のための病態生理２　改訂第５版
  
  Volume: 47 Pages: 686-690
- Data Source
  KAKENHI-PROJECT-26461562
[Journal Article] 総説　先天性血小板減少症の診断と分子病態2014
- Author(s)
  笹原洋二
- Journal Title
  
  小児科
  
  Volume: 55(1) Pages: 105-114
- Data Source
  KAKENHI-PROJECT-26461562
[Journal Article] A nationwide survey of Aicardi-Goutieres syndrome patients identifies a strong association between dominant TREX1 mutations and chilblain lesions: Japanese cohort study.2014
- Author(s)
  Abe J, Nakamura K, Nishikomori R, Kato M, Mitsuiki N, Izawa K, Awaya T, Kawai T, Yasumi T, Toyoshima I, Hasegawa K, Ohshima Y, Hiragi T, Sasahara Y, Suzuki Y, Kikuchi M, Osaka H, Ohya T, Ninomiya S, Fujikawa S, Akasaka M, Iwata N, Kawakita A, Funatsuka M, Shintaku H, Ohara O, Ichinose H, Heike T.
- Journal Title
  
  Rheumatology
  
  Volume: 53(3) Pages: 448-458
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] Binding of WASP/N-WASP interacting protein WIP to actin regulates focal adhesion assembly and adhesion.2014
- Author(s)
  Ramesh N, Massaad MJ, Kumar L, Suresh K, Sasahara Y, Anton I, Bhasin M, Libermann T, Geha RS.
- Journal Title
  
  Mol. Cell. Biol.
  
  Volume: 34(14) Pages: 2600-2610
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461562
[Journal Article] IDH2 and TP53 mutations are correlated with gliomagenesis in a patient with Maffucci syndrome.2014
- Author(s)
  Moriya M, Kato Kaneko M, Liu X, Hosaka M, Fujishima F, Sakuma J, Ogasawara S, Watanabe M, Sasahara Y, Kure S, Kato Y.
- Journal Title
  
  Cancer Science
  
  Volume: 105(3) Pages: 359-362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] Selective expansion of regulatory T cells in mixed chimera after allogeneic bone marrow transplantation in a patient with IPEX syndrome.2014
- Author(s)
  Horino S, Sasahara Y, Satoh M, Niizuma H, Kumaki S, Abukawa D, Satoh A, Imaizumi M, Kanegane H, Kamachi Y, Sasaki S, Terui K, Ito Y, Kobayashi I, Ariga T, Tsuchiya S, Kure S.
- Journal Title
  
  Pediatr. Transplant.
  
  Volume: 188(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] Mesenchymal chondrosarcoma diagnosed by FISH for HEY1-NCOA2 fusion gene.2014
- Author(s)
  Moriya K, Katayama S, Onuma M, Hosaka M, Watanabe M, Hasegawa T, Sasahara Y, Kure S.
- Journal Title
  
  Pediatr. Int.
  
  Volume: in press.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] Open conformation of WASP regulates its nuclear localization and gene transcription in myeloid cells.2014
- Author(s)
  Looi CY, Sasahara Y, Watanabe Y, Satoh M, Hakozaki I, Du W, Uchiyama T, Kumaki S, Kure S, Tsuchiya S.
- Journal Title
  
  Int. Immunol.
  
  Volume: 26(6) Pages: 341-352
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] 総説　先天性血小板減少症の診断と分子病態2014
- Author(s)
  笹原洋二
- Journal Title
  
  小児科
  
  Volume: 55(1) Pages: 105-114
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] Binding of WASP/N-WASP interacting protein WIP to actin regulates focal adhesion assembly and adhesion.2014
- Author(s)
  Ramesh N, Massaad MJ, Kumar L, Suresh K, Sasahara Y, Anton I, Bhasin M, Libermann T, Geha RS.
- Journal Title
  
  Mol. Cell. Biol.
  
  Volume: 34(14) Pages: 2600-2610
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] Unilateral phrenic nerve pulsy: A rare manifestation of vincristine neurotoxicity.2014
- Author(s)
  Moriya K, Kakisaka Y, Onuma M, Sasahara Y, Kure S.
- Journal Title
  
  Indian J Pediatr.
  
  Volume: in press.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] The open conformation of WASP regulates its nuclear localization and gene transcription in myeloid cells.2014
- Author(s)
  2.Looi CY, Sasahara Y, Watanabe Y, Sato M, Hakozaki I, Uchiyama M, Wong WF, Uchiyama T, Kumaki S, Tsuchiya S, Kure S
- Journal Title
  
  International Immnology
  
  Volume: 26 Issue: 6 Pages: 341-352
- DOI
  10.1093/intimm/dxt072
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860836, KAKENHI-PROJECT-26461562, KAKENHI-PROJECT-26461597, KAKENHI-PROJECT-26860780
[Journal Article] GNE myopathy associated with congenital thrombocytopenia: a report of two siblings.2014
- Author(s)
  Izumi R, Niihori T, Suzuki N, Sasahara Y, Nishiyama A, Nishiyama S, Endo K, Kato M, Warita H, Konno H, Tateyama M, Nagashima T, Funayama R, Nakayama K, Kure S, Matsubara Y, Aoki Y, Aoki M.
- Journal Title
  
  Neuromuscul. Disord.
  
  Volume: 24(12) Issue: 12 Pages: 1068-1072
- DOI
  10.1016/j.nmd.2014.07.008
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23591528, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-26461520, KAKENHI-PROJECT-26461562, KAKENHI-PROJECT-26670085, KAKENHI-PROJECT-26830064
[Journal Article] 総説　小型および正常サイズの血小板を有する先天性血小板減少症の診断と分子病態における最近の知見2013
- Author(s)
  笹原洋二、大内芽里、今泉益栄
- Journal Title
  
  日本小児血液がん学会雑誌
  
  Volume: 50(2) Pages: 186-191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] PBSCT is associated with poorer survival and increased chronic GVHD than BMT in Japanese patients with acute leukemia and HLA-matched sibling donor.2013
- Author(s)
  Shinzato A, Tabuchi K, Atsuta Y, Inoue M, Inagaki J, Yabe H, Koh K, Kato K, Ohta H, Kigasawa H, Kitoh T, Ogawa A, Takahashi Y, Sasahara Y, Kato S, Adachi S.
- Journal Title
  
  Pediatr. Blood & Cancer
  
  Volume: 60(9) Pages: 1573-1579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] A case series of CAEBV of children and young adults treated with reduced intensity conditioning and allogeneic bone marrow transplantation; a single center study.2013
- Author(s)
  Watanabe Y, Sasahara Y, Satoh M, Looi CY, Katayama S, Suzuki T, Suzuki N, Ouchi M, Horino S, Moriya K, Nanjyo Y, Onuma M, Kitazawa H, Irie M, Niizuma H, Uchiyama T, Rikiishi T, Kumaki S, Minegishi M, Wada T, Yachie A, Tsuchiya T, Kure S.
- Journal Title
  
  Eur. J. Haematol.
  
  Volume: 91 Pages: 242-248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] Wiskott-Aldrich syndrome presenting with a clinical picture mimicking juvenile myelomonocytic leukemia.2013
- Author(s)
  Yoshimi A, Kamachi Y, Imai K, Watanabe N, Kobayashi R, Yoshida M, Kobayashi C, Hama A, Muramatsu H, Sasahara Y, Morio T, Nonoyama S, Ehl S, Manabe A, Niemeyer C, Kojima S, et al.
- Journal Title
  
  Pediatr Blood & Cancer
  
  Volume: 60 Pages: 836-841
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] Interstitial lung disease in two brothers with novel compound heterozygous ABCA3 mutations.2013
- Author(s)
  Kitazawa H, Moriya K, Niizuma H, Kawano K, Saito-Nanjo Y, Uchiyama T, Rikiishi T, Sasahara Y, Sakamoto O, Setoguchi Y, Kure S.
- Journal Title
  
  Eur. J. Pediatr.
  
  Volume: 172(7) Pages: 953-957
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] Degradation of the Wiskott-Aldrich syndrome protein by calpain and the ubiquitin-proteasome pathway regulates T cell receptor (TCR) driven F-actin assembly.2013
- Author(s)
  Watanabe Y, Sasahara Y, Ramesh N, Massaad MJ, Looi CY, Kumaki S, Kure S, Geha RS, Tsuchiya S.
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] Successful treatment with rituximab of an infant with refractory autoimmune hemolytic anemia.2013
- Author(s)
  Moriya K, Matsuhashi T, Onuma M, Niizuma H, Rikiishi T, Asada H, Suzuki J, Sasahara Y, Kure S.
- Journal Title
  
  Int. J. Hematol.
  
  Volume: 98(2) Pages: 237-239
- NAID
  10031194740
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] B-cell function after unrelated umbilical cord blood transplantation using a minimal-intensity conditioning regimen in patients with X-SCID.2013
- Author(s)
  Kumaki S, Sasahara Y, Kamachi Y, Muramatsu H, Morio T, Goi K, Sugita K, Urabe T, Takada H, Kojima S, Tsuchiya S, Hara T.
- Journal Title
  
  Int. J. Hematol.
  
  Volume: 98 Pages: 355-360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] Wiskott-Aldrich syndrome presenting with a clinical picture mimicking juvenile myelomonocytic leukemia.2013
- Author(s)
  Oshimi A, Kamachi Y, Imai K, Watanabe N, Kinoshita A, Nakadate H, Kanazawa T, Oozono S, Kobayashi R, Yoshida M, Kobayashi C, Hama A, Muramatsu H, Sasahara Y, Jakob M, Morio T, Nonoyama S, Ehl S, Manabe A, Niemeyer C, Kojima S.
- Journal Title
  
  Pediatr. Blood & Cancer
  
  Volume: 60(5) Pages: 836-841
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] Long-term outcome of childhood aplastic anemia patients who underwent allogeneic hematopoietic stem cell transplantation from HLA-matched sibling dono in Japan.2013
- Author(s)
  Kikuchi A, Yabe H, Kato K, Koh K, Inagaki J, Sasahara Y, Suzuki R, Yoshida N, Kudo K, Kobayashi R, Tabuchi K, Kawa K, Kojima S.
- Journal Title
  
  Bone Marrow Transplant.
  
  Volume: 48(5) Pages: 657-660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] 免疫不全症を伴う特徴的な症候群　その１―Wiskott-Aldrich症候群、高IgE症候群―2013
- Author(s)
  笹原洋二
- Journal Title
  
  小児科診療
  
  Volume: 76(3) Pages: 407-412
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] T cell receptor ligation causes Wiskott-Aldrich syndrome protein degradation and F-actin assembly downregulation.2013
- Author(s)
  Watanabe Y, Sasahara Y, Ramesh N, Massaad MJ, Looi CY, Kumaki S, Kure S, Geha RS, Tsuchiya S.
- Journal Title
  
  J. Allergy Clin. Immunol.
  
  Volume: 132 Pages: 648-655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] Long-term outcome of childhood aplastic anemia patients who underwent allogeneic hematopoietic stem cell transplantation from an HLA-matched sibling donor in Japan.2013
- Author(s)
  Kikuchi A, Yabe H, Kato K, Koh K, Inagaki J, Sasahara Y, Suzuki R, YoshidaN, Kudo K, Kobayashi R, Tabuchi K, Kawa K, Kojima S, for the Japanese Hematopoietic Cell Transplantation Registry
- Journal Title
  
  Bone Marrow Transplant
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] 小型および正常サイズの血小板を有する先天性血小板減少症の診断と分子病態における最近の知見2013
- Author(s)
  笹原洋二
- Journal Title
  
  日本小児血液がん学会雑誌
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] Interstitial lung disease in two brothers with novel compound heterozygous ABCA3 mutations.2013
- Author(s)
  Kitazawa H, Moriya K, Niizuma H, Kawano K, Saito-Nanjo Y, Uchiyama T, Rikiishi T, Sasahara Y, Sakamoto O, Setoguchi Y, Kure S.
- Journal Title
  
  Eur J Pediatr
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] Development of a multi-step leukemogenesis model of MLL-rearranged leukemia using humanized mice.2012
- Author(s)
  Moriya K, Suzuki M, Watanabe Y, Takahashi T, Aoki Y, Uchiyama T, Kumaki S, Sasahara Y, Minegishi M, Kure S, Tsuchiya S, Sugamura K, Ishii N.
- Journal Title
  
  PLoS One
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] DiGeorge症候群2012
- Author(s)
  笹原洋二
- Journal Title
  
  小児疾患の診断治療基準　改訂４版
  
  Volume: 44 Pages: 234-235
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] 複合免疫不全症2012
- Author(s)
  笹原洋二
- Journal Title
  
  小児の発熱A to Z
  
  Volume: 増刊号 Pages: 155-159
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] Stem cell transplantation for pediatric patients with non-anaplastic peripheral T-cell lymphoma in Japan.2012
- Author(s)
  Kobayashi R, Fujita N, Mitsui T, Iwasaki F, Suzumiya J, Kuroda H, Nishimura R,Sasahara Y, Takeshita Y, Kato K, Okumura H, Sakamaki H, Yabe H, Kawa K, Kato K, Suzuki R.
- Journal Title
  
  Br J Hematol
  
  Volume: 159 Pages: 88-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] Second allogeneic hematopoietic SCT for relapsed ALL in children.2012
- Author(s)
  Kato M , Horikoshi Y , Okamoto Y, Takahashi Y, Hasegawa D, Koh K, Takita J, Inoue M, Kigasawa H, Ogawa A, Sasahara Y, Kawa K, Yabe H, Sakamaki H, Suzuki R, Kato K.
- Journal Title
  
  Bone Marrow Transplant
  
  Volume: 1 Pages: 1-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] Casitas B-cell lymphoma mutation in childhood T-cell acute lymphoblastic leukemia.2012
- Author(s)
  Saito Y, Aoki Y, Muramatsu H, Makishima H, Maciejewski JP, Imaizumi M, Rikiishi T, Sasahara Y, Kure S, Niihori T, Tsuchiya S, Kojima S, and Matsubara Y.
- Journal Title
  
  Leukemia Res
  
  Volume: 36 Pages: 1009-1015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] Identification of FOXP3-negative regulatory T-like (CD4+CD25+CD127low)cells in patients with immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome.2011
- Author(s)
  Otsubo K, Kanegane H, Sasahara Y, Ochs HD, Miyawaki T, et al.
- Journal Title
  
  Clin. Immunol.
  
  Volume: 141 Pages: 111-120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] Vincristine-resistant Kasabach-Meritt phenomenon successfully treated With low-dose irradiation.2011
- Author(s)
  Watanabe Y, Sasahara Y, et al.
- Journal Title
  
  Int.J.Hematol.
  
  Volume: 93 Pages: 126-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591242
[Journal Article] Autoantibodies to villin occur frequently in IPEX, a severe immune dysregulatiosyndrome caused by mutation of FOXP3.2011
- Author(s)
  Kobayashi I, Kubota M, Sasahara Y, Whitesell L, Ariga T, et al.
- Journal Title
  
  Clin. Immunol.
  
  Volume: 141 Pages: 83-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] Octa-arginine mediated delivery of wild-type Lnk inhibits Jak2-dependent leukemia cell growth by promoting apoptosis.2011
- Author(s)
  Chung YL, Sasahara Y, Futaki S, Tsuchiya S, Kumaki S, et al.
- Journal Title
  
  PLOS One
  
  Volume: 6(8)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] Vincristine-resistant Kasabach-Meritt phenomenon successfully treated with low-dose irradiation.2011
- Author(s)
  Watanabe Y, Sasahara Y, Tsuchiya S, ほか
- Journal Title
  
  Int.J.Hematol. 93
  
  Pages: 126-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591242
[Journal Article] Nationwide survey of patients with primary immunodeficiency diseases in Japan.2011
- Author(s)
  Ishimura M, Takada H, Sasahara Y, Miyawaki T, Hara T, et al.
- Journal Title
  
  J. Clin. Immunol.
  
  Volume: 1 Pages: 1-5
- NAID
  120005133089
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591528
[Journal Article] 4度の造血幹細胞移植を施行した重症再生不良性貧血に1例における内分泌学的合併症2010
- Author(s)
  管野潤子、笹原洋二, 他
- Journal Title
  
  日本小児血液学会雑誌
  
  Volume: 24(1) Pages: 47-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591242
[Journal Article] 4度の造血幹細胞移植を施行した重症再生不良性貧血に1例における内分泌学的合併症2010
- Author(s)
  管野潤子、笹原洋二、土屋滋、ほか
- Journal Title
  
  日本小児血液学会雑誌 24(1)
  
  Pages: 47-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591242
[Journal Article] Refractory chronic immune thrombocytopenic purpura in a chila with acute lymphoblastic leukemia.2009
- Author(s)
  Horino S, Sasahara Y, et al.
- Journal Title
  
  Int.J.Hematol. 90
  
  Pages: 483-485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591242
[Journal Article] Refractory chronic immune thrombocytopenic purpura in a child with acute lymphoblastic leukemia.2009
- Author(s)
  Horino S, Sasahara Y, Tsuchiya S, ほか
- Journal Title
  
  Int.J.Hematol. 90
  
  Pages: 483-485
- NAID
  10026109509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591242
[Journal Article] Identification of severe combined immunodeficiency by T-cell receptor excision circles quiantification using Guthrie cards.2009
- Author(s)
  Morinishi Y, Sasahara Y, et al.
- Journal Title
  
  J.Pediatr. 155(6)
  
  Pages: 829-833
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591242
[Journal Article] Identification of severe combined immunodeficiency by T-cell receptor excision circles quiantification using Guthrie cards.2009
- Author(s)
  Morinishi Y, Sasahara Y, Nonoyama S, ほか
- Journal Title
  
  J.Pediatr. 155(6)
  
  Pages: 829-833
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591242
[Journal Article] WIP is a chaperone for Wiskott-Aldrich syndrome protein (WASP)2007
- Author(s)
  De la Fuente MA*, Sasahara Y*, et al.(*co-first authors)
- Journal Title
  
  Proc. Natl. Acad. Sci. USA. 104(3)
  
  Pages: 926-931
- Data Source
  KAKENHI-PROJECT-16689020
[Journal Article] A second-site mutation in the initiation codon of WAS (WASP) gene results in expansion of subsets of lymphocytes in an Wiskott-Aldrich Syndrome patient.2006
- Author(s)
  Du W, Kumaki S, Uchiyama S, Yachi A, Chung Yeng L, Kawai S, Minegishi M, Ramesh N, Geha RS, Sasahara Y, Tsuchiya S.
- Journal Title
  
  Hum Mutat. 27
  
  Pages: 370-5
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390294
[Journal Article] Application of HSVtk suicide gene to X-SCID gene therapy : Ganciclovir treatment offsets gene corrected X-SCID B cells.2006
- Author(s)
  Uchiyama T, Kumaki S, Ishikawa Y, Onodera M, Sato M, Du W, Sasahara Y, Tanaka N, Sugamura K, Tsuchiya S.
- Journal Title
  
  Bioch Bioph Res Comm 341
  
  Pages: 391-398
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390320
[Journal Article] WIP regulates WASP homeostasis2006
- Author(s)
  Sasahara Y, Ramesh N, et al.
- Journal Title
  
  Immunity (submitted)
- Data Source
  KAKENHI-PROJECT-16689020
[Journal Article] Application of HSVtk suicide gene to X-SCID gene therapy : Ganciclovir treatment offsets gene corrected X-SCID B cells.2006
- Author(s)
  Uchiyama T, Kumaki S, Ishikawa Y, Onodera M, Sato M, Du W, Sasahara Y, Tanaka N, Sugamura K, Tsuchiya S.
- Journal Title
  
  Biochem Biophys Res Commun. 341
  
  Pages: 391-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390294
[Journal Article] Application of HSVtk suicide gene to X-SCID gene therapy : Ganciclovir treatment offsets gene corrected X-SCID B cells.2006
- Author(s)
  Uchiyama T, Kumaki S, Ishikawa Y, Onodera M, Sato M, Du W, Sasahara Y, Tanaka N, Sugamura K, Tsuchiya S
- Journal Title
  
  BBRC 341
  
  Pages: 391-398
- Data Source
  KAKENHI-PROJECT-16390294
[Journal Article] A second-site mutation in the initiation codon of WAS (WASP) gene results in expansion of subsets of lymphocytes in an Wiskott-Aldrich Syndrome patient.2006
- Author(s)
  Du W, Kumaki S, Uchiyama S, Yachi A, Chung Yeng L, Kawai S, Minegishi M, Ramesh N, Geha RS, Sasahara Y, Tsuchiya S.
- Journal Title
  
  Human Genet (In Press)
- Data Source
  KAKENHI-PROJECT-16390294
[Journal Article] A second-site mutation in the initiation codon of WAS (WASP) gene results in expansion of subsets of lymphocytes in an Wiskott-Aldrich Syndrome patient.2006
- Author(s)
  Du W, Kumaki S, Uchiyama T, Yachie A, Kawai S, Minegishi M, Ramesh N, Geha RF, Sasahara Y, Tsuchiya S.
- Journal Title
  
  Hum Mutat 27
  
  Pages: 370-375
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390320
[Journal Article] Application of HSVtk suicide gene to X-SCID gene therapy : Ganciclovir treatment offsets gene corrected X-SCID B cells.2006
- Author(s)
  Uchiyama T, Kumaki S, Ishikawa Y, Onodera M Sato M, Du W, Sasahara Y, Tanaka N, Sugamura K, Tsuchiya S
- Journal Title
  
  BBRC 341
  
  Pages: 391-398
- Data Source
  KAKENHI-PROJECT-16659269
[Journal Article] A second-site mutation in the initiation codon of WAS (WASP) gene results in expansion of subsets of lymphocytes in an Wiskott-Aldrich Syndrome patient.2006
- Author(s)
  Du W, Kumaki S, Uchiyama S, Yachi A, Chung Yeng L, Kawai S, Minegishi M, Ramesh N, Geha RS, Sasahara Y, Tsuchiya S.
- Journal Title
  
  Human Genet (In Press)
- Data Source
  KAKENHI-PROJECT-16659269
[Journal Article] A second-site mutation in the initiation codon of WASP gene results in expansion of subsets of lymphocytes in a Wiskott-Aldrich syndrome patient2006
- Author(s)
  Du W, Sasahara Y, et al.
- Journal Title
  
  Human Mutation (In press)
- Data Source
  KAKENHI-PROJECT-16689020
[Journal Article] A novel JAK3 mutation in a Japanese patient with severe combined immunodeficiency.2005
- Author(s)
  Uchiyama T, Kumaki S, Fujiwara M, Nishida Y, Hakozaki I, Imai K, Du W, Yoshinari M, Sasahara Y, Tsuchiya S.
- Journal Title
  
  Pediatr Int. 47
  
  Pages: 575-578
- NAID
  10016939145
- Data Source
  KAKENHI-PROJECT-16390294
[Journal Article] A novel JAK3 mutation in a Japanese patient with severe combined immunodeficiency2005
- Author(s)
  Ucniyama T, Sasahara Y, et al.
- Journal Title
  
  Pediatr.Int. 47(5)
  
  Pages: 575-578
- NAID
  10016939145
- Data Source
  KAKENHI-PROJECT-16689020
[Journal Article] Application of HSVtk suicide gene to X-SCID gene therapy : Ganciclovir treatment offsets gene corrected X-SCID B cells.2005
- Author(s)
  Uchiyama T, Sasahara Y, et al.
- Journal Title
  
  Biocnem.Biophy.Res.Comm. 341(2)
  
  Pages: 391-398
- Data Source
  KAKENHI-PROJECT-16689020
[Journal Article] A novel JAK3 mutation in a Japanese patient with severe combined immunodeficiency.2005
- Author(s)
  Uchiyama T, Kumaki S, Fujiwara M, Nishida Y, Hakozaki I, Imai K, Du W, Yoshinari M, Sasahara Y, Tsuchiya S.
- Journal Title
  
  Pediatr Int 47
  
  Pages: 575-578
- NAID
  10016939145
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390320
[Journal Article] 総説Wiskott-Aldrich症候群の分子病態-最近の知見から-2005
- Author(s)
  笹原洋二, 土屋滋
- Journal Title
  
  臨床免疫、日本臨床免疫学会誌 28(3)
  
  Pages: 140-147
- Data Source
  KAKENHI-PROJECT-16689020
[Journal Article] A novel JAK3 mutation in a Japanese patient with severe combined immunodeficiency.2005
- Author(s)
  Uchiyama T, Kumaki S, Fujiwara M, Nishida Y, Hakozaki I, Imai K, Du W, Yoshinari M, Sasahara Y, Tsuchiya S.
- Journal Title
  
  Pediatr Int. 47
  
  Pages: 575-578
- NAID
  10016939145
- Data Source
  KAKENHI-PROJECT-16659269
[Journal Article] WIP regulates signaling via the high affinity receptor for IgE in mast cells.2004
- Author(s)
  Kettner A, Sasahara Y, et al.
- Journal Title
  
  Journal of Experimental Medicine 199(3)
  
  Pages: 357-368
- Data Source
  KAKENHI-PROJECT-16689020
[Journal Article] WASPによる免疫シナプス形成の制御2004
- Author(s)
  笹原洋二
- Journal Title
  
  Molecular Medicine臨時増刊号<免疫2005> 41
  
  Pages: 160-164
- Data Source
  KAKENHI-PROJECT-16689020
[Journal Article] Wiskott-Aldrich症候群2004
- Author(s)
  笹原洋二, 土屋滋
- Journal Title
  
  小児内科特集免疫不全症 36(11)
  
  Pages: 1771-1777
- Data Source
  KAKENHI-PROJECT-16689020
[Presentation] 妊娠・出産を経験した先天性血栓性血小板減少性紫斑病の一例2024
- Author(s)
  笹原洋二、戒能明、菊池敦生、他。
- Organizer
  第15回東北小児血液疾患研究会
- Data Source
  KAKENHI-PROJECT-23K07286
[Presentation] 妊娠・出産を経験した実症例から学ぶ先天性血栓性血小板減少性紫斑病2023
- Author(s)
  笹原洋二
- Organizer
  第59回日本周産期・新生児医学会
- Data Source
  KAKENHI-PROJECT-23K07286
[Presentation] Wiskott-Aldrich症候群および白血球接着不全症1型における免疫学的シナプス形成後のサイトカイン産生異常2023
- Author(s)
  笹原洋二、和田泰三、森尾友宏
- Organizer
  第126回日本小児科学会学術集会
- Data Source
  KAKENHI-PROJECT-23K07286
[Presentation] 特別講演：先天性血小板減少症の診断と治療における最近の知見2022
- Author(s)
  笹原洋二
- Organizer
  第90回東海小児血液懇話会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08855
[Presentation] 腸管合併症を呈するPID2021
- Author(s)
  笹原洋二
- Organizer
  第4回日本免疫不全・自己炎症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08855
[Presentation] 東北地区における原発性免疫不全症治療について2021
- Author(s)
  笹原洋二
- Organizer
  第10回東北免疫不全症研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08855
[Presentation] 教育講演　先天性血小板減少症・異常症2021
- Author(s)
  笹原洋二
- Organizer
  第83回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08855
[Presentation] 原発性免疫不全症におけるゲノム医療の新展開2017
- Author(s)
  笹原洋二
- Organizer
  第79回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-26461562
[Presentation] 特発性血小板減少性紫斑病を合併し血清TARC値が低値であったアトピー性皮膚炎の1例2017
- Author(s)
  小澤麻紀、笹原洋二、相場節也
- Organizer
  第116回日本皮膚科学会総会
- Place of Presentation
  仙台市、仙台国際センター
- Data Source
  KAKENHI-PROJECT-26461562
[Presentation] 単一血球減少と免疫不全症2016
- Author(s)
  笹原洋二
- Organizer
  第58回日本小児血液・がん学会学術集会
- Place of Presentation
  品川区、品川プリンスホテル
- Invited
- Data Source
  KAKENHI-PROJECT-26461562
[Presentation] 当科で診断した遺伝性血小板減少症とその分子病態2016
- Author(s)
  笹原洋二
- Organizer
  第9回東北小児血液疾患研究会
- Place of Presentation
  仙台市、江陽グランドホテル
- Data Source
  KAKENHI-PROJECT-26461562
[Presentation] ITPと鑑別が必要な原発性免疫不全症と遺伝性血小板減少症2016
- Author(s)
  笹原洋二
- Organizer
  第1回道北免疫不全症講演会
- Place of Presentation
  旭川市、旭川グランドホテル
- Invited
- Data Source
  KAKENHI-PROJECT-26461562
[Presentation] Invited lecture: Hematopoietic stem cell transplantation for primary immunodeficiency and inborn errors of metabolism: a Japanese multicenter study.2015
- Author(s)
  Sasahara Y
- Organizer
  The Pediatric Hematology and Oncology Precision Therapy Forum
- Place of Presentation
  復旦大学、上海市、中華人民共和国
- Year and Date
  2015-11-06
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461562
[Presentation] 特別講演: ITPと鑑別が必要な先天性血小板減少症・免疫不全症2015
- Author(s)
  笹原洋二
- Organizer
  第1回山形血液研究会
- Place of Presentation
  ホテルメトロポリタン山形、山形市、山形県
- Year and Date
  2015-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-26461562
[Presentation] 招待講演: ＩＴＰと鑑別が必要な小型・正常大の血小板を有する先天性血小板減少症2015
- Author(s)
  笹原洋二
- Organizer
  第23回日本小児ITP研究会
- Place of Presentation
  甲府富士屋ホテル、甲府市、山梨県
- Year and Date
  2015-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-26461562
[Presentation] ＩＴＰと鑑別が必要な先天性血小板減少症・免疫不全症2015
- Author(s)
  笹原洋二
- Organizer
  第15回若葉小児科臨床研究会
- Place of Presentation
  生田会館（神戸）
- Year and Date
  2015-02-21
- Invited
- Data Source
  KAKENHI-PROJECT-26461562
[Presentation] 招待講演　ITPと鑑別が必要な先天性血小板減少症・免疫不全症2015
- Author(s)
  笹原洋二
- Organizer
  第15回若葉小児科臨床研究会
- Place of Presentation
  生田会館（神戸）
- Year and Date
  2015-02-21
- Invited
- Data Source
  KAKENHI-PROJECT-23591528
[Presentation] Plenary session: 小型・正常大の血小板を有する先天性血小板減少症の臨床的および遺伝学的解析2015
- Author(s)
  笹原洋二、内山芽里、今泉益栄、呉繁夫
- Organizer
  第57回日本小児血液・がん学会学術集会
- Place of Presentation
  甲府富士屋ホテル、甲府市、山梨県
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-26461562
[Presentation] 原発性免疫不全症から考察する小児IBD2014
- Author(s)
  笹原洋二
- Organizer
  第14回日本小児IBD研究会
- Place of Presentation
  東京都
- Invited
- Data Source
  KAKENHI-PROJECT-23591528
[Presentation] 原発性免疫不全症に対する造血幹細胞移植ー日本全体の概要と当科症例からー2014
- Author(s)
  笹原洋二、佐藤大記、齋藤麻耶子、森谷邦彦、渡辺祐子、小沼正栄、力石健、久間木悟、峯岸正好、土屋滋、呉繁夫
- Organizer
  第37回仙台BMT懇話会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-23591528
[Presentation] 当科におけるCAEBV移植5症例の検討2013
- Author(s)
  笹原洋二　大内芽里　鈴木信　堀野智史　小沼正栄　入江正寛　内山徹　力石健峯岸正好　呉繁夫
- Organizer
  第36回仙台BMT懇話会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-23591528
[Presentation] 同胞間同種骨髄移植後、ドナーT細胞にEBVゲノムが確認されたCAEBVの１例2013
- Author(s)
  笹原洋二、渡辺祐子、小沼正栄、入江正寛、内山徹、力石健、呉繁夫
- Organizer
  第22回EBV感染症研究会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-23591528
[Presentation] WASPとIL-10受容体遺伝子変異を同定した乳児期発症炎症性腸疾患2症例の臨床的検討2013
- Author(s)
  笹原洋二、鈴木資、片山紗乙莉、大内芽里、鈴木信、小沼正栄、内山徹、入江正寛、力石健、呉繁夫
- Organizer
  第32回東北免疫研究会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-23591528
[Presentation] シンポジウム3 小児免疫不全症の現状と展望　免疫不全症に対する造血幹細胞移植2013
- Author(s)
  笹原洋二
- Organizer
  第55回日本小児血液がん学会学術集会
- Place of Presentation
  福岡市
- Invited
- Data Source
  KAKENHI-PROJECT-23591528
[Presentation] WASPとIL-10受容体遺伝子変異を同定した乳児期発症炎症性腸疾患の2症例2013
- Author(s)
  笹原洋二、鈴木資、片山紗乙莉、大内芽里、鈴木信、小沼正栄、内山徹、入江正寛、力石健、呉繁夫
- Organizer
  第3回東北小児感染免疫研究会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-23591528
[Presentation] WASPとIL-10受容体遺伝子変異を同定した乳児期発症炎症性腸疾患2症例の臨床的検討2013
- Author(s)
  笹原洋二、大内芽里、鈴木信、鈴木資、片山紗乙莉、入江正寛、呉繁夫、浅田洋司、角田文彦、虻川大樹
- Organizer
  第116回日本小児科学会学術集会
- Place of Presentation
  広島市
- Data Source
  KAKENHI-PROJECT-23591528
[Presentation] RISTを施行した当科年長児および成人期WAS/XLT3症例の臨床的検討2012
- Author(s)
  笹原洋二、鈴木信、大内芽里、渡辺祐子、小沼正栄、入江正寛、内山徹、力石健、峯岸正好
- Organizer
  第25回東北BMT研究会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-23591528
[Presentation] 細胞外寄生菌に対する感染防御機構2012
- Author(s)
  笹原洋二
- Organizer
  第44回日本小児感染症学会
- Place of Presentation
  北九州市
- Invited
- Data Source
  KAKENHI-PROJECT-23591528
[Presentation] Functional roles of WIP in Wiskott-Aldrich syndrome2012
- Author(s)
  Yoji Sasahara, Yuko Watanabe, Looi Chung Yeng, Shigeru Tsuchiya, Shigeo Kure.
- Organizer
  8th Congress of Asian Society for Pediatric Research
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-23591528
[Presentation] Spontaneous reversionを伴う原発性免疫不全症2症例における長期的臨床経過の検討2012
- Author(s)
  笹原洋二、佐藤美季、斉藤由佳、小沼正栄、入江正寛、内山徹、力石健、呉繁夫
- Organizer
  第115回日本小児科学会学術集会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-23591528
[Presentation] Mechanisms of ubiquitination and degradation of Wiskott-Aldrich syndrome protein inT cells.2011
- Author(s)
  Yoji Sasahara, Yuko Watanabe, Looi Chung Yeng, Shigeru Tsuchiya.
- Organizer
  7th Asian Society for Pediatric Research/Pediatric Academic Society 2011 joint meeting
- Place of Presentation
  Denver, CO, USA.
- Data Source
  KAKENHI-PROJECT-23591528
[Presentation] Role of WIP in Wiskott-Aldrich syndrome2010
- Author(s)
  Yoji Sasahara
- Organizer
  The 2^<nd> Symposium for PID in Asia
- Place of Presentation
  千葉、かずさDNA研究所
- Year and Date
  2010-02-04
- Data Source
  KAKENHI-PROJECT-20591242
[Presentation] Wiskott-Aldrich症候群の分子病態からみた感染症とWIPの役割2010
- Author(s)
  笹原洋二
- Organizer
  第42回日本小児感染症学会
- Place of Presentation
  仙台
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-20591242
[Presentation] 骨髄非破壊的前処置にて造血幹細胞移植を施行した原発性免疫不全症6症例の検討2010
- Author(s)
  笹原洋二、土屋滋, 他
- Organizer
  第72回日本血液学会
- Place of Presentation
  横浜
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-20591242
[Presentation] ITPとの鑑別に重要なWAS/XLTの分子病態におけるWIPの役割2010
- Author(s)
  笹原洋二、土屋滋、他
- Organizer
  第52回日本小児血液学会
- Place of Presentation
  大阪
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-20591242
[Presentation] 骨髄非破壊的前処置にて造血幹細胞移植を施行した原発性免疫不全症6症例の検討2010
- Author(s)
  笹原洋二、土屋滋、他
- Organizer
  第113回日本小児科学会学術集会
- Place of Presentation
  盛岡
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-20591242
[Presentation] 悪性リンパ腫を合併したWiskott-Aldrich症候群患者に対するRISTによる骨髄移植の経験2010
- Author(s)
  力石健、笹原洋二、他
- Organizer
  第32回日本造血細胞移植学会総会
- Place of Presentation
  浜松
- Year and Date
  2010-02-20
- Data Source
  KAKENHI-PROJECT-20591242
[Presentation] Wiskott-Aldrich症候群の分子病態の多様性とWIP欠損症発見の試み2010
- Author(s)
  笹原洋二、土屋滋、他
- Organizer
  第72回日本血液学会
- Place of Presentation
  横浜
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-20591242
[Presentation] 骨髄非破壊的前処置にて造血幹細胞移植を施行した原発性免疫不全症6症例の検討2010
- Author(s)
  笹原洋二、土屋滋、他
- Organizer
  第72 回日本血液学会
- Place of Presentation
  横浜
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-20591242
[Presentation] Functional analysis of constitutively active forms of WASP2009
- Author(s)
  Chung Yeng Looi, Yoji Sasahara, Yuko Watanabe, Satoru Kumaki, Shigeru Tsuchiva
- Organizer
  第112回日本小児科学会学術集会
- Place of Presentation
  奈良県文化会館・奈良県新公会堂・奈良商工会議所・奈良中小企業会館
- Data Source
  KAKENHI-PROJECT-19390280
[Presentation] ABCA3遺伝子の変異を認めた特発性間質性肺炎の兄弟例2009
- Author(s)
  川野研悟, 北沢博, 新妻秀剛, 斉藤由佳, 坂本修, 笹原洋二, 土屋滋
- Organizer
  第112回日本小児科学会学術集会
- Place of Presentation
  奈良県文化会館・奈良県新公会堂・奈良商工会議所・奈良中小企業会館
- Data Source
  KAKENHI-PROJECT-19390280
[Presentation] ダブルフィラデルフィア染色体陽性の急性リンパ性白血病の1例2009
- Author(s)
  渡辺庸平, 鈴木信, 力石健, 笹原洋二, 土屋滋
- Organizer
  第51回日本小児血液学会
- Place of Presentation
  東京ベイホテル東急
- Data Source
  KAKENHI-PROJECT-19390280
[Presentation] 派生染色体不均衡転座der(1;7)(q10;p10)を持つ6歳MDS女児に且齊帯血移植した1例2009
- Author(s)
  星能元, 笹原洋二, 力石健, 斉藤由佳, 新妻秀剛, 小沼正栄, 久間木悟, 土屋滋
- Organizer
  第112回日本小児科学会学術集会
- Place of Presentation
  奈良県文化会館・奈良県新公会堂・奈良商工会議所・奈良中小企業会館
- Data Source
  KAKENHI-PROJECT-19390280
[Presentation] 同種骨髄移植後特異な臨床経過をたどった重症複合免疫不全症の3例2008
- Author(s)
  久間木悟, 峯岸正好, 笹原洋二, 熊谷直憲, 根東義明, 谷内江昭宏, 土屋滋
- Organizer
  第50回日本小児血液学会
- Place of Presentation
  幕張メッセ国際会議場
- Data Source
  KAKENHI-PROJECT-19390280
[Presentation] WASP異常症の多様性とその分子病態の解明に向けて2008
- Author(s)
  笹原洋二, 渡辺祐子, Chen Looi Yeng, 佐藤美季, 箱崎郁子, 久間木悟, 土屋滋
- Organizer
  第50回日本小児血液学会
- Place of Presentation
  幕張メッセ国際会議場
- Data Source
  KAKENHI-PROJECT-19390280
[Presentation] 22q11.2領域の Germline deletion をベースに発症した乳児悪性ラブドイド腫瘍2008
- Author(s)
  新妻秀剛, 力石健, 笹原洋二, 岸本光司, 大平美紀, 中川原章, 久間木悟, 土屋滋
- Organizer
  第24回日本小児がん学会
- Place of Presentation
  幕張メッセ国際会議場
- Data Source
  KAKENHI-PROJECT-19390280
[Presentation] 宮城県における造血幹細胞移植後患者の内分泌学的晩期障害2008
- Author(s)
  菅野潤子, 吉成みやこ, 笹原洋二, 佐藤篤, 藤原幾磨, 小川英伸, 峯岸正好, 今泉益栄, 久間木悟, 土屋滋
- Organizer
  第111回日本小児科学会学術集会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-19390280
[Presentation] Meettheex pert ; Waltzing with WASP2008
- Author(s)
  笹原洋二
- Organizer
  第50回日本小児血液学会
- Place of Presentation
  幕張
- Year and Date
  2008-11-16
- Data Source
  KAKENHI-PROJECT-20591242
[Presentation] WIP is a chaperone fro Wiskott-Aldrich syndrome protein2008
- Author(s)
  Sasahara y, Ramesh N, Tsuchiya S, Geha R.
- Organizer
  50th annual meeting, American Society of Hematology
- Place of Presentation
  San Francisco/California
- Data Source
  KAKENHI-PROJECT-19390280
[Presentation] Meet the expert ; Waltzing with WASP2008
- Author(s)
  笹原洋二
- Organizer
  第50回日本小児血液学会
- Place of Presentation
  幕張
- Year and Date
  2008-11-16
- Data Source
  KAKENHI-PROJECT-20591242
[Presentation] WIP is a chaperone for WASP2008
- Author(s)
  Yoji Sasahara, Shigeru Tsuchiya, et.al.
- Organizer
  第50回米国血液学会
- Place of Presentation
  サンフランシスコ(米国)
- Data Source
  KAKENHI-PROJECT-20591242
[Presentation] 免疫不全症に合併した悪性リンパ腫2例2008
- Author(s)
  青木由貴, 遠藤明史, 満生紀子, 小野敏明, 磯田健志, 冨澤大輔, 高木正稔, 梶原道子, 長澤正之, 森尾友宏, 水谷修紀, 笹原洋二, 久間木悟, 土屋滋, 大石力
- Organizer
  第50回日本小児血液学会
- Place of Presentation
  幕張メッセ国際会議場
- Data Source
  KAKENHI-PROJECT-19390280
[Presentation] WASP異常症の多様性とその分子病態の解明に向けて2008
- Author(s)
  笹原洋二、土屋滋、他
- Organizer
  第50回日本小児血液学会
- Place of Presentation
  幕張
- Year and Date
  2008-11-15
- Data Source
  KAKENHI-PROJECT-20591242
[Presentation] 骨髄非破壊的前処置を用いた同胞間造血幹細胞移植を行った高IgM症候群の一例2008
- Author(s)
  斉藤由佳, 笹原洋二, 新妻秀剛, 川野研悟, 堀野智史, 星能元, 峯岸正好, 久間木悟, 土屋滋
- Organizer
  第50回日本小児血液学会
- Place of Presentation
  幕張メッセ国際会議場
- Data Source
  KAKENHI-PROJECT-19390280
[Presentation] 原発巣と転移巣で異なる性質を持つと考えられた神経芽腫の2例2008
- Author(s)
  川野研悟, 堀野智史, 新妻秀剛, 齊藤由佳, 力石健, 笹原洋二, 久間木悟, 峯岸正好, 土屋滋
- Organizer
  第24回日本小児がん学会
- Place of Presentation
  幕張メッセ国際会議場
- Data Source
  KAKENHI-PROJECT-19390280
[Presentation] RISTによる臍帯血移植を施行したX連鎖重症複合免疫不全症の1例2008
- Author(s)
  鈴木力生, 笹原洋二, 渡辺祐子, 堀野智史, 久間木悟, 土屋滋
- Organizer
  第111回日本小児科学会学術集会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-19390280
[Presentation] WIP is a chaperone for WASP2008
- Author(s)
  Yoji Sasahara
- Organizer
  50^<th> American Society of Hematology (第50回米国血液学会) Annual Meeting
- Place of Presentation
  サンフランシスコ(米国)
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-20591242
[Presentation] 慢性活動性EBV感染症の4例2008
- Author(s)
  渡辺祐子, 阿部弘, 新妻秀剛, 星能元, 力石健笹原洋二, 坂本修, 吉成みやこ, 久間木悟, 土屋滋
- Organizer
  第111回日本小児科学会学術集会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-19390280
[Presentation] Spontaneous reversionを伴う白血球接着不全症I型症例の病態解析2007
- Author(s)
  笹原洋二, 他
- Organizer
  第110回日本小児科学会学術集会
- Place of Presentation
  京都
- Year and Date
  2007-04-21
- Data Source
  KAKENHI-PROJECT-19390280
[Presentation] 教育講演　ITPと鑑別が必要な血小板疾患
- Author(s)
  笹原洋二
- Organizer
  第56回日本小児血液がん学会学術集会
- Place of Presentation
  岡山コンベンションセンター（岡山）
- Year and Date
  2014-11-28 – 2014-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-23591528
[Presentation] T cell receptor ligation causes Wiskott-Aldrich syndrome protein degradation and F-actin assembly downregulation in T cells.
- Author(s)
  Sasahara Y, Watanabe Y, Kure S, Massaad MJ, Ramesh N, Geha RS.
- Organizer
  6th Biennial Meeting of the European Society for Immunodeficiencies
- Place of Presentation
  プラハコングレスセンター（プラハ）
- Year and Date
  2014-10-29 – 2014-11-01
- Data Source
  KAKENHI-PROJECT-26461562
[Presentation] ＩＴＰと鑑別が必要な血小板疾患
- Author(s)
  笹原洋二
- Organizer
  第56回日本小児血液がん学会学術集会
- Place of Presentation
  岡山コンベンションセンター（岡山）
- Year and Date
  2014-11-28 – 2014-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-26461562
[Presentation] RISTを施行した当科年長児および成人期WAS/XLT3症例の臨床的検討
- Author(s)
  笹原洋二、力石健、北沢博、内山徹、峯岸正好、久間木悟、土屋滋
- Organizer
  第5回日本免疫不全症研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591528
[Presentation] Tcell receptor ligation causes Wiskott-Aldrich syndrome protein degradation and F-actin assembly downregulation in T cells.
- Author(s)
  Sasahara Y, Watanabe Y, Massaad MJ, Ramesh N, Geha RS.
- Organizer
  6th Biennial Meeting of the European Society for Immunodeficiencies.
- Place of Presentation
  プラハコングレスセンター（プラハ）
- Year and Date
  2014-10-29 – 2014-11-01
- Data Source
  KAKENHI-PROJECT-23591528

1. TSUCHIYA Shigeru (30124605)

# of Collaborated Projects: 5 results

# of Collaborated Products: 25 results
2. KUMAKI Satoru (20311566)

# of Collaborated Projects: 4 results

# of Collaborated Products: 19 results
3. Kamibeppu Kiyoko (70337856)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. SATO Iori (20622252)

# of Collaborated Projects: 1 results

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5. KITA Sachiko (70757046)

# of Collaborated Projects: 1 results

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6. SOEJIMA Takafumi (00768989)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MINEGISHI Masayoshi (20211592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. WATANABE YUKO (40610671)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 石井直人 (60291267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 新妻秀剛 (30392252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
11. 塩飽仁 (50250808)

# of Collaborated Projects: 1 results

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12. 本多奈美 (60282133)

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13. 小見山智恵子 (60581634)

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14. 森下美紀 (10758840)

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15. 池田真理 (70610210)

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16. 阿南和昭 (80343036)

# of Collaborated Projects: 1 results

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17. RIKIISHI Ken

# of Collaborated Projects: 1 results

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18. INOUE Yukiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. SUZUKI Yuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. IMAIZUMI Masue

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. NAGOYA Yuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. YAMANE Yuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. TAKAHASHI Momoko

# of Collaborated Projects: 1 results

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24. HAYASAKA Hiroe

# of Collaborated Projects: 1 results

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25. TUDA Reiko

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26. GOTO Minami

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27. TAKAHASHI Yukari

# of Collaborated Projects: 1 results

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28. SATO ATUSHI

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. HIRATA Youichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. IWASAKI Miwa

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# of Collaborated Products: 0 results
31. SATAKE Kazuyo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. KIKUCHI Ryota

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. HOSHI Yasutaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. OSUKI Yuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. KAZAMA Yukari

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. TERAUCHI Chie

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. TAKEUCHI Ayaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. MAEDA Miho

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. ISHIDA Yasusi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. KOH Katuyosi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. FUKUCHI Tomoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. TANAKA Harumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. INOUE Masami

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. WATANABE Kentaro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. TAKITA Junko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. TOKUYAMA Mika

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. WATANABE Kenichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. TADA Keiichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. MOURI Mirei

# of Collaborated Projects: 1 results

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50. SUZUKI Miho

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
51. OHNO Sinji

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52. YAMAUCHI Hideko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
53. TAKEI Junko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
54. YUBUNE Kuniko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
55. NAKAMURA Seigo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
56. FUKUCHIMOTO Harumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
57. KURIHARA Kayoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
58. EMOTO Shun

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
59. TOBE hiromi

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# of Collaborated Products: 0 results
60. SUZUKI Seigo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
61. NAKAMURA Mayumi

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# of Collaborated Products: 0 results
62. NAKAJIMA Shohei

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
63. OSHIRO Rei

# of Collaborated Projects: 1 results

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64. UMESHITA Kaori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
65. KOBAYASHI Asuka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
66. MURATA Sho

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67. KIBI Satoshi

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68. NIIHORI Tetsuya

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# of Collaborated Products: 2 results
69. 森谷邦彦

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# of Collaborated Products: 1 results
70. 青木洋子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
71. 松原洋一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
72. 阿部太紀

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# of Collaborated Products: 1 results
73. 内山徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

sasahara yoji 笹原 洋二

Sasahara Yoji 笹原 洋二

SASAHARA Yoji 笹原 洋二

Research Projects

Research Products

Co-Researchers

Prpposal of novel inherited thrombocytopenias by clarifying molecular pathogenesis of cytoskeletal signaling and hematopoiesis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of comprehensive genetic analysis and proposal of novel disease entities in inherited thrombocytopenias.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

How to support compiled transition childhood survivors and their families have experienced

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Responsible genes and molecular pathogenesis of inherited thrombocytopenia with small or normal-sized plateletsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The open conformation of WASP regulates its nuclear localization and gene transcription in myeloid&nbsp;cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on molecular pathogenesis of X-linked neutropenia and WIP deficiency by using NOG mice and human myeloid cell line.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clinical significance of WASP protein complex in nucleus.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Leukemogenesis due to insertional mutagenesis-a NOG mouse model-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

X連鎖重症複合免疫不全症に対するキメラ二重鎖切断酵素を利用した遺伝子治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

神経芽腫腫瘍抗原に対する人工免疫グロブリンレセプターを利用した新規免疫療法の開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Wiskott-Aldrich症候群の分子病態の解明とType2-WASの提唱Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Induction of human cytotoxic T cells by peptide-pulsed universal antigen presenting cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new and safer gene therapy method for severe combined immunodeficiency.

Principal Investigator

sasahara yoji 笹原洋二

Sasahara Yoji 笹原洋二

SASAHARA Yoji 笹原洋二

The open conformation of WASP regulates its nuclear localization and gene transcription in myeloid cells

[Book] 臨床免疫・アレルギー科　CDC42が誘導するインフラマソームの新たな炎症誘導機構2023

[Book] 別冊　日本臨牀　血液症候群（第3版）Ⅱ　ーその他の血液疾患を含めてー　Wiskott-Aldrich症候群2023

[Book] 血液専門医テキスト（改訂第4版）　先天性血小板減少症・機能異常症2023

[Book] 原発性免疫不全症候群　診療の手引き（改訂第2版）　ウィスコット・オルドリッチ（Wiskott-Aldrich症候群）（WAS）2023

[Book] ITP　小児科診療ガイドライン-最新の診療指針-第5版2022

[Journal Article] 総説　先天性血小板減少症・異常症の診療ガイド2021

[Journal Article] 総説　先天性血小板減少症・異常症2021