Ueda Kazutaka 上田和孝

Researcher Number	60375798
Other IDs	https://orcid.org/0000-0002-0509-1840
Affiliation (Current)	2024: 国際医療福祉大学, その他部局等, 准教授 2024: 東京大学, 医学部附属病院, 特任講師
Affiliation (based on the past Project Information) *help	2020 – 2024: 東京大学, 医学部附属病院, 助教 2016 – 2019: 東京大学, 医学部附属病院, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / Medium-sized Section 52:General internal medicine and related fields / Obstetrics and gynecology
Keywords	Principal Investigator マクロファージ / 血管周囲脂肪 / 炎症 / 脂肪褐色化 / 動脈硬化 / 肥満 / エストロゲン / 細胞間相互作用 / β3受容体 / 血管周囲脂肪組織 … More / 急性大動脈解離 / 臓器周囲脂肪組織 / 炎症性サイトカイン / 血管傷害 / 褐色化 / 血管リモデリング / 視床下部 / エストロゲン受容体 / 性ホルモン / 性ステロイドホルモン / シグナル伝達 / 中枢神経 / 糖尿病 / 褐色脂肪 / 女性ホルモン / 中枢神経系 Less

器官周囲脂肪組織の空間的機能解析技術の構築と疾患メカニズム解明Principal Investigator
- Principal Investigator
  
  上田和孝
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  The University of Tokyo
血管の組織修復における細胞間相互作用の解明Principal Investigator
- Principal Investigator
  
  上田和孝
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  The University of Tokyo
A New Approach to Postmenopausal Atherosclerotic Disease Based on "Vascular Beiging"Principal Investigator
- Principal Investigator
  
  Ueda Kazutaka
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  The University of Tokyo
Estrogen-mediated regulation of energy balance via adipocyte beigingPrincipal Investigator
- Principal Investigator
  
  Ueda Kazutaka
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Tie2-Cre-Induced Inactivation of Non-Nuclear Estrogen Receptor-α Signaling Abrogates Estrogen Protection Against Vascular Injury2023
- Author(s)
  Liu Pang-Yen、Fukuma Nobuaki、Hiroi Yukio、Kunita Akiko、Tokiwa Hiroyuki、Ueda Kazutaka、Kariya Taro、Numata Genri、Adachi Yusuke、Tajima Miyu、Toyoda Masayuki、Li Yuxin、Noma Kensuke、Harada Mutsuo、Toko Haruhiro、Ushiku Tetsuo、Kanai Yoshimitsu、Takimoto Eiki、Liao James K.、Komuro Issei
- Journal Title
  
  JACC: Basic to Translational Science
  
  Volume: 8 Issue: 1 Pages: 55-67
- DOI
  10.1016/j.jacbts.2022.07.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16064, KAKENHI-PROJECT-22K16097, KAKENHI-PROJECT-22K16130, KAKENHI-PROJECT-20K07422, KAKENHI-PROJECT-22K08515, KAKENHI-PROJECT-21H02908, KAKENHI-PROJECT-20K07739
[Journal Article] Vertebral osteomyelitis secondary to infective endocarditis detected by repeated magnetic resonance imaging: a case report2023
- Author(s)
  Hashimoto Masaki、Ueda Kazutaka、Nakao Tomoko、Tanaka Takahiro、Komuro Issei
- Journal Title
  
  European Heart Journal - Case Reports
  
  Volume: 7 Issue: 11
- DOI
  10.1093/ehjcr/ytad552
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02908
[Journal Article] PGC-1α-mediated angiogenesis prevents pulmonary hypertension in mice2023
- Author(s)
  Fujiwara T, Takeda N, Hara H, Ishii S, Numata G, Tokiwa H, Katoh M, Maemura S, Suzuki T, Takiguchi H, Yanase T, Kubota Y, Nomura S, Hatano M, Ueda K, Harada M, Toko H, Takimoto E, Akazawa H, Morita H, Nishimura S, Komuro I.
- Journal Title
  
  JCI Insight
  
  Volume: 8 Issue: 17 Pages: 162632-162632
- DOI
  10.1172/jci.insight.162632
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16064, KAKENHI-PROJECT-22K16066, KAKENHI-PROJECT-22K08276, KAKENHI-PROJECT-23K07473, KAKENHI-PROJECT-21K08023, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-21H02908, KAKENHI-PROJECT-23K27352
[Journal Article] Novel AGL variants in a patient with glycogen storage disease type IIIb and pulmonary hypertension caused by pulmonary veno-occlusive disease: A case report2023
- Author(s)
  Shindo Akito、Ueda Kazutaka、Minatsuki Shun、Nakayama Yukiteru、Hatsuse Satoshi、Fujita Kanna、Nomura Seitaro、Hatano Masaru、Takeda Norifumi、Akazawa Hiroshi、Komuro Issei
- Journal Title
  
  Frontiers in Genetics
  
  Volume: 14 Pages: 1148067-1148067
- DOI
  10.3389/fgene.2023.1148067
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-21K08023, KAKENHI-PROJECT-22H00471, KAKENHI-PROJECT-21H02908
[Journal Article] The emerging role of estrogen's non-nuclear signaling in the cardiovascular disease2023
- Author(s)
  Tokiwa Hiroyuki、Ueda Kazutaka、Takimoto Eiki
- Journal Title
  
  Frontiers in Cardiovascular Medicine
  
  Volume: 10
- DOI
  10.3389/fcvm.2023.1127340
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16064, KAKENHI-PROJECT-21H02908
[Journal Article] Perivascular adipose tissue in vascular pathologies-a novel therapeutic target for atherosclerotic disease?2023
- Author(s)
  Adachi Yusuke、Ueda Kazutaka、Takimoto Eiki
- Journal Title
  
  Frontiers in Cardiovascular Medicine
  
  Volume: 10 Pages: 1151717-1151717
- DOI
  10.3389/fcvm.2023.1151717
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16097, KAKENHI-PROJECT-21H02908
[Journal Article] A pacing-controlled protocol for frequency-diastolic relations distinguishes diastolic dysfunction specific to a mouse HFpEF model2022
- Author(s)
  Numata Genri、Takimoto Eiki、Kariya Taro、Adachi Yusuke、Tokiwa Hiroyuki、Toyoda Masayuki、Mafune Ryo、Saito Yoshihiro、Nakamura Shun、Ueda Kazutaka、Ikeda Yuichi、Komuro Issei
- Journal Title
  
  American Journal of Physiology-Heart and Circulatory Physiology
  
  Volume: 323 Issue: 3 Pages: H523-H527
- DOI
  10.1152/ajpheart.00241.2022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16064, KAKENHI-PROJECT-22K16097, KAKENHI-PROJECT-22K16130, KAKENHI-PROJECT-22KJ1202, KAKENHI-PROJECT-21H02908
[Journal Article] Beiging of perivascular adipose tissue regulates its inflammation and vascular remodeling2022
- Author(s)
  Adachi Yusuke、Ueda Kazutaka、Nomura Seitaro、Ito Kaoru、Katoh Manami、Katagiri Mikako、Yamada Shintaro、Hashimoto Masaki、Zhai Bowen、Numata Genri、Otani Akira、Hinata Munetoshi、Hiraike Yuta、Waki Hironori、Takeda Norifumi、Morita Hiroyuki、Ushiku Tetsuo、Yamauchi Toshimasa、Takimoto Eiki、Komuro Issei
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 5117-5117
- DOI
  10.1038/s41467-022-32658-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16097, KAKENHI-PROJECT-22K16130, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19K17976, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-22H00471, KAKENHI-PROJECT-21H02908
[Journal Article] Factors associated with left ventricular reverse remodelling after percutaneous coronary intervention in patients with left ventricular systolic dysfunction2021
- Author(s)
  Adachi Y、Kiyosue A、Ando J、Kawahara T、Kodera S、Minatsuki S、Kikuchi H、Inaba T、Kiriyama H、Hirose K、Shinohara H、Saito A、Fujiwara T、Hara H、Ueda K、Sakakura K、Hatano M、Harada M、Takimoto E、Akazawa H、Morita H、Momomura S、Fujita H、Komuro I
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 239-239
- DOI
  10.1038/s41598-020-80491-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08097, KAKENHI-PROJECT-19K17667, KAKENHI-PROJECT-18K08096, KAKENHI-PROJECT-21H02908
[Journal Article] Three-Dimensional Visualization of Hypoxia-Induced Pulmonary Vascular Remodeling in Mice2021
- Author(s)
  Fujiwara Takayuki、Takeda Norifumi、Hara Hironori、Ishii Satoshi、Numata Genri、Tokiwa Hiroyuki、Maemura Sonoko、Suzuki Takaaki、Takiguchi Hiroshi、Kubota Yoshiaki、Seo Kinya、Sakata Asuka、Nomura Seitaro、Hatano Masaru、Ueda Kazutaka、Komuro Issei
- Journal Title
  
  Circulation
  
  Volume: 144 Issue: 17 Pages: 1452-1455
- DOI
  10.1161/circulationaha.121.056219
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08096, KAKENHI-PROJECT-19K11662, KAKENHI-PROJECT-21H04821, KAKENHI-PROJECT-21K16110, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-21K08023, KAKENHI-PROJECT-21H02908
[Journal Article] Estrogen Receptor-α Non-Nuclear Signaling Confers Cardioprotection and?Is?Essential to cGMP-PDE5 Inhibition?Efficacy2020
- Author(s)
  Fukuma Nobuaki、Takimoto Eiki、Ueda Kazutaka、Liu Pangyen、Tajima Miyu、Otsu Yu、Kariya Taro、Harada Mutsuo、Toko Haruhiro、Koga Kaori、Blanton Robert M.、Karas Richard H.、Komuro Issei
- Journal Title
  
  JACC: Basic to Translational Science
  
  Volume: 5 Issue: 3 Pages: 282-295
- DOI
  10.1016/j.jacbts.2019.12.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11662, KAKENHI-PROJECT-17H01560, KAKENHI-PROJECT-18K08096
[Journal Article] Regulatory Actions of Estrogen Receptor Signaling in the Cardiovascular System2020
- Author(s)
  Ueda K, Adachi Y, Liu P, Fukuma N, Takimoto E
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: 10 Pages: 909-909
- DOI
  10.3389/fendo.2019.00909
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18J13507, KAKENHI-PROJECT-18K08096
[Journal Article] Overview of the 83<sup>rd</sup> Annual Scientific Meeting of the Japanese Circulation Society　― Renaissance of Cardiology for the Creation of Future Medicine ―2019
- Author(s)
  Akazawa H, Toko H, Harada M, Ueda K, Kodera S, Kiyosue A, Fujiu K, Hatano M, Daimon M, Ando J, Takimoto E, Morita H, Komuro I
- Journal Title
  
  Circ J
  
  Volume: 83 Issue: 9 Pages: 1829-1835
- DOI
  10.1253/circj.CJ-19-0587
- NAID
  130007695023
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2019-08-23
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08097, KAKENHI-PROJECT-17H01560, KAKENHI-PROJECT-18K08096
[Journal Article] Endothelial Cell?Derived Angiocrines Elicit Physiological Cardiomyocyte Hypertrophy2019
- Author(s)
  Ueda Kazutaka、Toko Haruhiro、Komuro Issei
- Journal Title
  
  Circulation
  
  Volume: 139 Issue: 22 Pages: 2585-2587
- DOI
  10.1161/circulationaha.119.040632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11662, KAKENHI-PROJECT-17H01560, KAKENHI-PROJECT-18K08096
[Journal Article] Membrane-Initiated Estrogen Receptor Signaling Mediates Metabolic Homeostasis via Central Activation of Protein Phosphatase 2A2018
- Author(s)
  Ueda Kazutaka、Takimoto Eiki、Lu Qing、Liu Pangyen、Fukuma Nobuaki、Adachi Yusuke、Suzuki Ryo、Chou Shengpu、Baur Wendy、Aronovitz Mark J.、Greenberg Andrew S.、Komuro Issei、Karas Richard H.
- Journal Title
  
  Diabetes
  
  Volume: 67 Issue: 8 Pages: 1524-1537
- DOI
  10.2337/db17-1342
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09776, KAKENHI-PROJECT-18K08096
[Journal Article] Subendocardial Ischemia Because of Coronary Artery Spasm Causes Transient Severe Mitral Regurgitation.2018
- Author(s)
  Kaneko M, Ueda K, Nishimae I, Nitta S, Suzuki M, Kasao M, Shirai T.
- Journal Title
  
  Circ Heart Fail.
  
  Volume: 11 Issue: 12
- DOI
  10.1161/circheartfailure.118.005496
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08096
[Journal Article] Unliganded estrogen receptor alpha regulates vascular cell function and gene expression2017
- Author(s)
  Lu Qing、Schnitzler Gavin R.、Vallaster Caroline S.、Ueda Kazutaka、Erdkamp Stephanie、Briggs Christine E.、Iyer Lakshmanan K.、Jaffe Iris Z.、Karas Richard H.
- Journal Title
  
  Mol Cell Endocrinol
  
  Volume: 442 Pages: 12-23
- DOI
  10.1016/j.mce.2016.11.019
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20174
[Journal Article] ER Alpha Rapid Signaling Is Required for Estrogen Induced Proliferation and Migration of Vascular Endothelial Cells2016
- Author(s)
  Lu Q, Schnitzler GR, Ueda K, Iyer LK, Diomede OI, Andrade T, Karas RH.
- Journal Title
  
  PLOS ONE
  
  Volume: 11 Issue: 4 Pages: e0152807-e0152807
- DOI
  10.1371/journal.pone.0152807
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20174
[Presentation] Protects the Heart against Ischemic Damage through Regulating Lipid Metabolism in Myocardium2023
- Author(s)
  Guo J, Ueda K, Toko H, Harada M, Bujo S, Ishizuka M, Adachi A, Hashimoto M, Komuro I.
- Organizer
  第87回日本循環器学会総会
- Data Source
  KAKENHI-PROJECT-21H02908
[Presentation] Beiging of perivascular adipose tissue regulates its inflammation and vascular remodeling2023
- Author(s)
  Kazutaka Ueda
- Organizer
  第87回日本循環器学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02908
[Presentation] Pathophysiological significance of browning of perivascular adipose tissue in the development of atherosclerosis2019
- Author(s)
  Adachi Y, Ueda K, Ito K, Takimoto E, Komuro I.
- Organizer
  Annual Scientific Meeting of Japanese Circulation Society
- Data Source
  KAKENHI-PROJECT-18K08096
[Presentation] Pathophysiological Role of Browning of Perivascular Adipose Tissue in the Development of Vascular Remodeling2019
- Author(s)
  Adachi Y, Ueda K, Ito K, Takimoto E, Komuro I.
- Organizer
  Annual Symposium of the American Heart Association scientific sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08096
[Presentation] Pathophysiological Significance of Browning of Perivascular Adipose Tissue in the Development of Atherosclerosis.2019
- Author(s)
  Adachi Y, Ueda K, Ito K, Takimoto E, Komuro I.
- Organizer
  Annual Symposium of the American Heart Association Council on Basic Cardiovascular Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08096
[Presentation] Phenotypic change of perivascular adipose tissue associated with endovascular damage2019
- Author(s)
  Adachi Y, Ueda K, Ito K, Takimoto E, Komuro I.
- Organizer
  第2回日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-18K08096
[Presentation] Pathophysiological Significance of Browning of Perivascular Adipose Tissue in the Development of Atherosclerosis2019
- Author(s)
  Adachi Y, Ueda K, Ito K, Takimoto E, Komuro I
- Organizer
  第3回日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-18K08096
[Presentation] Phenotypic change of perivascular adipose tissue associated with endovascular damage.2018
- Author(s)
  Adachi Y, Ueda K, Ito K, Takimoto E, Komuro I.
- Organizer
  第22回日本心不全学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08096
[Presentation] Phenotypic change of perivascular adipose tissue associated with endovascular damage2018
- Author(s)
  Adachi Y, Ueda K, Ito K, Takimoto E, Komuro I.
- Organizer
  第2回日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-18K08096
[Presentation] エストロゲン受容体 Rapid, non-genomic シグナル経路による代謝恒常性の制御2016
- Author(s)
  上田和孝、瀧本英樹、Richard H. Karas、小室一成
- Organizer
  日本臨床分子医学会学術集会学術奨励(YIA)セッション
- Place of Presentation
  東京
- Year and Date
  2016-04-15
- Data Source
  KAKENHI-PROJECT-16K20174
[Presentation] エストロゲン受容体 Rapid, non-genomic シグナル経路による代謝恒常性の制御2016
- Author(s)
  上田和孝、瀧本英樹、Richard H. Karas、小室一成
- Organizer
  日本心血管内分泌代謝学会学術集会
- Place of Presentation
  東京
- Year and Date
  2016-12-06
- Data Source
  KAKENHI-PROJECT-16K20174

1. TAKIMOTO Eiki (20709513)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. 和田洋一郎 (10322033)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 佐藤守俊 (00323501)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. AKAZAWA Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. SUZUKI Ryo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. Chou Shengpu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 東口治弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 常盤洋之

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
9. 小室一成

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 安達裕助

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Ueda Kazutaka 上田 和孝

Research Projects

Research Products

Co-Researchers

器官周囲脂肪組織の空間的機能解析技術の構築と疾患メカニズム解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

血管の組織修復における細胞間相互作用の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A New Approach to Postmenopausal Atherosclerotic Disease Based on "Vascular Beiging"Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Estrogen-mediated regulation of energy balance via adipocyte beigingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Tie2-Cre-Induced Inactivation of Non-Nuclear Estrogen Receptor-α Signaling Abrogates Estrogen Protection Against Vascular Injury2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Vertebral osteomyelitis secondary to infective endocarditis detected by repeated magnetic resonance imaging: a case report2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PGC-1α-mediated angiogenesis prevents pulmonary hypertension in mice2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel AGL variants in a patient with glycogen storage disease type IIIb and pulmonary hypertension caused by pulmonary veno-occlusive disease: A case report2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The emerging role of estrogen's non-nuclear signaling in the cardiovascular disease2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Perivascular adipose tissue in vascular pathologies-a novel therapeutic target for atherosclerotic disease?2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A pacing-controlled protocol for frequency-diastolic relations distinguishes diastolic dysfunction specific to a mouse HFpEF model2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Beiging of perivascular adipose tissue regulates its inflammation and vascular remodeling2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Factors associated with left ventricular reverse remodelling after percutaneous coronary intervention in patients with left ventricular systolic dysfunction2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Three-Dimensional Visualization of Hypoxia-Induced Pulmonary Vascular Remodeling in Mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Estrogen Receptor-α Non-Nuclear Signaling Confers Cardioprotection and?Is?Essential to cGMP-PDE5 Inhibition?Efficacy2020

Author(s)

Ueda Kazutaka 上田和孝

[Journal Article] Overview of the 83<sup>rd</sup> Annual Scientific Meeting of the Japanese Circulation Society　― Renaissance of Cardiology for the Creation of Future Medicine ―2019