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ishiyama ken  石山 謙

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Ishiyama Ken  石山 謙

ISHIYAMA Ken  石山 謙

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Researcher Number 60377380
Other IDs
External Links
Affiliation (Current) 2025: 国立健康危機管理研究機構, 国立国際医療センター, 医長
Affiliation (based on the past Project Information) *help 2016 – 2022: 金沢大学, 附属病院, 講師
2011: 金沢大学, 医学系, 協力研究員
2004: Kanazawa University Hospital, Instructor, 医学部附属病院, 助手
Review Section/Research Field
Principal Investigator
Basic Section 54010:Hematology and medical oncology-related / Hematology
Except Principal Investigator
Hematology / Laboratory medicine
Keywords
Principal Investigator
血液免疫学 / WT1 / トロンボポエチン受容体作動薬 / minute PNH顆粒球 / クロナリティ / miniscule PNH顆粒球 / クローン性造血 / 体細胞遺伝子変異 / ロミプロスチム / トロンボポエチン受容体作動薬(TPO-RA) … More / 再生不良性貧血 / LRCH1 / 13番染色体長腕の部分欠失(del(13q) / CD109 / 赤血球分化 / TGF-β / OLFM4 / 13番染色体長腕の部分欠失(del(13q)) / 自己免疫性造血不全 … More
Except Principal Investigator
HLA-DR15 / DRS-1 / 自己抗体 / PNH / 再生不良性貧血 / 白血病 / 癌 / バイオマーカー / 骨髄異形成症候群 / moesin / autoantigen / aplastic anemia / 慢性骨髄性白血病 / モエシン / RB遺伝子 / 13q- / GPI-アンカー膜蛋白 / PNH型血球 / 骨髄不全 / CD109 / TGF-β / GPIアンカー膜蛋白 / 自己抗原 / 細胞傷害性T細胞 / HLA / 6pUPD Less
  • Research Projects

    (5 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (11 People)
  •  Effects of romiplostim, a thrombopoietin receptor agonist, on hematopoiesis and DNA repairPrincipal Investigator

    • Principal Investigator
      Ishiyama Ken
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Kanazawa University
  •  Analysis of mechanisms underlying preferential commitment of hematopoietic stem cells with del(13q) in patients with autoimmune hematopoietic failurePrincipal Investigator

    • Principal Investigator
      Ishiyama Ken
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Kanazawa University
  •  Development of diagnostic kit for myelodysplastic anemia

    • Principal Investigator
      Sugiyama Daisuke
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Laboratory medicine
    • Research Institution
      Kyushu University
  •  Identification of auto-antigens which trigger the development of immune-mediated bone marrow failure

    • Principal Investigator
      NAKAO Shinji
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Kanazawa University
  •  Analysis of autoantigens in aplastic anemia : identification of an epitope recognized by CD4^+ T cells specific to hematopoietic progenitor cells

    • Principal Investigator
      NAKAO Shinji
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Kanazawa University

All 2022 2021 2020 2011 2009 2004

All Journal Article Presentation

  • [Journal Article] Clinical significance of the increased expression of the WT1 gene in peripheral blood of patients with acquired aplastic anemia2022

    • Author(s)
      Ishiyama Ken、Dung Tran Cao、Imi Tatsuya、Hosokawa Kohei、Nannya Yasuhito、Yamazaki Hirohito、Ogawa Seishi、Nakao Shinji
    • Journal Title

      eJHaem

      Volume: 3 Issue: 4 Pages: 1116-1125

    • DOI

      10.1002/jha2.563

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08367, KAKENHI-PROJECT-20K08708
  • [Journal Article] Frequent HLA-DR loss on hematopoietic stem progenitor cells in patients with cyclosporine-dependent aplastic anemia carrying HLA-DR152022

    • Author(s)
      Tsuji Noriaki、Hosokawa Kohei、Urushihara Ryota、Tanabe Mikoto、Katagiri Takamasa、Ozawa Tatsuhiko、Takamatsu Hiroyuki、Ishiyama Ken、Yamazaki Hirohito、Kishi Hiroyuki、Ogawa Seishi、Nakao Shinji
    • Journal Title

      Leukemia

      Volume: 36 Issue: 6 Pages: 1666-1675

    • DOI

      10.1038/s41375-022-01549-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08367, KAKENHI-PROJECT-22K08473, KAKENHI-PROJECT-21H02962, KAKENHI-PROJECT-20K08707, KAKENHI-PROJECT-20K08708
  • [Journal Article] Paroxysmal nocturnal hemoglobinuria‐phenotype cells predict a good response to eltrombopag in patients with refractory aplastic anemia2020

    • Author(s)
      Ishiyama Ken、Sato Keijiro、Imi Tatsuya、Hosokawa Kohei、Kondo Yukio、Sugimori Naomi、Yamazaki Hirohito、Nakao Shinji
    • Journal Title

      eJHaem

      Volume: 1 Issue: 1 Pages: 243-248

    • DOI

      10.1002/jha2.51

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08708
  • [Journal Article] Origin and fate of blood cells deficient in glycosylphosphatidylinositol-anchored protein among patients with bone marrow failure2009

    • Author(s)
      Sugimori, C., Mochizuki, K., Qi, Z., Sugimori, N., Ishiyama, K., Kondo, Y., Yamazaki, H., Takami, A., Okumura, H., Nakao, S.
    • Journal Title

      Br J Haematol

      Volume: 147 Pages: 102-112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390291
  • [Journal Article] Origin and fate of blood cells deficient in glycosylphosphatidylino sitol-anchored protein among patients with bone marrow failure.2009

    • Author(s)
      Sugimori C, Mochizuki K, Qi Z, Sugimori N, Ishiyama K, Kondo Y, Yamazaki H, Takami A, Okumura H, Nakao S
    • Journal Title

      Br J Haematol 147

      Pages: 102-112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390291
  • [Journal Article] Graft-versus-leukemia effect of allogeneic stem cell transplantation : a Japanese single center study.2004

    • Author(s)
      Ishiyama K, Takami A, Shiobara S, Koizumi S, Nakao S
    • Journal Title

      Haemarologica 89-7

      Pages: 887-889

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390298
  • [Journal Article] Graft-versus-leukemia effect of allogeneic stem cell transplantation ; a Japanese single center study.2004

    • Author(s)
      Ishiyama K, et al.
    • Journal Title

      Haematologica 89・7

      Pages: 887-889

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390298
  • [Presentation] Presence of minute GPI(-) granulocytes represents non-immune pathophysiology of bone marrow failure2022

    • Author(s)
      Dung Cao Tran、Hiroki Mizumaki、Kohei Hosokawa、Hiroyuki Takamatsu、Hirohito Yamazaki、Ken Ishiyama、Toshihiro Miyamoto、Shinji Nakao
    • Organizer
      第84回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K08708
  • [Presentation] Low incidence of MDS-related gene mutations in patients with long-standing AA refractory to IST2022

    • Author(s)
      井美 達也、南谷 泰仁、材木 義隆、丸山 裕之、細川 晃平、吉田 晶代、高松 博幸、石山 謙、山崎 宏人、小川 誠司、宮本 敏浩、中尾 眞二
    • Organizer
      第84回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K08708
  • [Presentation] Markedly high prevalence of HLA-lacking leukocytes in patients with very severe aplastic anemia.2021

    • Author(s)
      10.Tatsuya Imi,Ryota Urushihara,Noriaki Tsuji,Mikoto Tanabe,Hiroki Mizumaki,Yoshitaka Zaimoku,Kohei Hosokawa,Hiroyuki Takamatsu,Ken Ishiyama,Hirohito Yamazaki,Shinji Nakao.
    • Organizer
      日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K08708
  • [Presentation] TPO-RA長期投与中の難治性再生不良性貧血患者では体細胞変異が検出されることは稀である2020

    • Author(s)
      井美達也、南谷泰仁、細川晃平、岩城憲子、高松博幸、石山謙、山﨑宏人、小川誠司、中尾眞二
    • Organizer
      日本血液学会学術集会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08708
  • [Presentation] Bone marrow failure with 13q deletion : A distinct clinicopathological entity with immune pathophysiology2011

    • Author(s)
      Hosokawa, K., Katagir, T., Sugimori, N., Ishiyama, K., Sasaki, Y., Seiki, Y., Sato-Otsubo, A., Sanad a, M., MD, Ogawa, S., Nakao, S.
    • Organizer
      The American Society of Hematology 53rd Annual Meeting
    • Place of Presentation
      San Diego Convention Center(California, USA.)
    • Year and Date
      2011-12-12
    • Data Source
      KAKENHI-PROJECT-21390291
  • [Presentation] Bone marrow failure with 13q deletion : A distinct clinicopat hological entity with immune pathophysiology2011

    • Author(s)
      Kohei Hosokawa, Takamasa Katagir, Naomi Sugimori, Ken Ishiyama, Yumi Sasaki, Yu Seiki, Aiko Sato-Otsubo, Masashi Sanada, MD, Seishi Ogawa, Shinji Nakao
    • Organizer
      The American Society of Hematology 53rd Annual Meeting
    • Place of Presentation
      San Diego Convention Center, California, USA
    • Year and Date
      2011-12-12
    • Data Source
      KAKENHI-PROJECT-21390291
  • 1.  NAKAO Shinji (70217660)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  YAMAZAKI Hirohito (50361994)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 3.  KONDO Yukio (10322116)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 4.  TAKAMATSU Hiroyuki (70401932)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  CHUHJO Tatsuya (00303298)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  TAKAMI Akiyoshi (80324078)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 7.  Sugiyama Daisuke (00426652)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  細道 一善 (50420948)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  OKAWA Katsuya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  中尾 真二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 10 results
  • 11.  細川 晃平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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