Fukui Hirokazu 福井広一

… Alternative Names

FUKUI Hirokazu 福井広一

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Researcher Number	60378742
Other IDs
Affiliation (Current)	2025: 兵庫医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 兵庫医科大学, 医学部, 教授 2016 – 2022: 兵庫医科大学, 医学部, 准教授 2010 – 2015: Dokkyo Medical University, 医学部, 講師 2008 – 2009: Dokkyo Medical University, 医学部, 准教授 2005 – 2006: 獨協医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related Except Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology
Keywords	Principal Investigator 臨床 / 再生医学 / 遺伝子 / 免疫学 / 感染症 / 腸内細菌 / Reg / 癌 / 消化管生理学 / mucosal regeneration … More / carcinogenesis / ulcerative colitis / 粘膜再生 / 発癌 / 潰瘍性大腸炎 / 感染 / 病理学 … More Except Principal Investigator 細胞間接着装置 / クローディン / タイト結合 / 腸内細菌叢 / 炎症性腸疾患 / バイオマーカー / 腸管免疫 / 糖鎖 / LRG / 好酸球性消化管疾患 / 遺伝子改変マウス / 膵再生 / 細胞死 / 肝臓の脂肪化 / CRISPR/Cas9 / 慢性膵炎 / 膵星細胞 / 急性膵炎 / Reg / メカニズム / 消化器症状 / 微小炎症持続 / 過敏性腸症候群 / 機能性消化管疾患 / クロディン / IL-33 / 非びらん性胃食道逆流症 / 機能性ディスペプシア Less

Role of Reg family proteins in the gastrointestinal environment and mucosal barrier functionPrincipal Investigator
- Principal Investigator
  
  福井広一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hyogo Medical University
Oligosaccharide-mediated regulation of intestinal inflammation by LRG, a novel serum biomarker for inflammatory bowel disease
- Principal Investigator
  
  新崎信一郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hyogo Medical University
Role of Reg family proteins in the link between dysbiosis and minimal inflammation in the gastrointestinal tractPrincipal Investigator
- Principal Investigator
  
  Fukui Hirokazu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hyogo Medical University
The role of Reg family in pancreatitis
- Principal Investigator
  
  Ohmuraya Masaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hyogo Medical University
Development of new therapy for eosinophilic gastrointestinal diseases targeting the regulation of mucosal barrier
- Principal Investigator
  
  Oshima Tadayuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hyogo Medical University
Alterations of gut microbiome and mucosal permeability in inactive IBD patients with IBS-like symptom
- Principal Investigator
  
  TOMITA TOSHIHIKO
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hyogo Medical University
Role of Reg protein on the mucosal barrier function in the inflammatory gastrointestinal diseasesPrincipal Investigator
- Principal Investigator
  
  Fukui Hirokazu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Hyogo Medical University
The development and application of in vivo evaluation of mucosal barrier function in functional gastrointestinal disorders
- Principal Investigator
  
  OSHIMA Tadayuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Hyogo Medical University
Role of Reg protein on the maintenance of mucosal homeostasis in the gastrointestinal tractPrincipal Investigator
- Principal Investigator
  
  Fukui Hirokazu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Hyogo Medical University
Duodenal epithelial intercellular junction and IL-33 on the development of dyspepsia
- Principal Investigator
  
  OSHIMA TADAYUKI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Hyogo Medical University
Protective role of Reg protein on mucosal injury in the gastrointestinal tractPrincipal Investigator
- Principal Investigator
  
  FUKUI Hirokazu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Hyogo Medical University
Role of REG protein in the regeneration and carcinogenesis of colorectal epithelial cellsPrincipal Investigator
- Principal Investigator
  
  FUKUI Hirokazu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Dokkyo Medical University
Roles of Reg protein in the pathophysiology of ulcerative colitisPrincipal Investigator
- Principal Investigator
  
  FUKUI Hirokazu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Dokkyo Medical University

[Book] 消化器癌転移と遺伝子異常2006
- Author(s)
  福井広一
- Total Pages
  6
- Publisher
  最新医学社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590635
[Book] 日本臨床2005
- Author(s)
  福井広一
- Total Pages
  5
- Publisher
  日本臨床社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590635
[Book] 日本臨床2005
- Author(s)
  福井広一
- Total Pages
  5
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-17590635
[Journal Article] Pegfilgrastim for the management of neutropenia during neoadjuvant chemotherapy with docetaxel, cisplatin, and 5-fluorouracil in esophageal cancer patients.2024
- Author(s)
  Yoshimoto T, Oshima T, Fukada T, Imamura N, Nakanishi T, Ebisutani N, Morishita D, Mieno M, Nakai K, Sei H, Kitayama Y, Eda H, Okugawa T, Tomita T, Fukui H, Shinzaki S.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 29 Issue: 2 Pages: 142-148
- DOI
  10.1007/s10147-023-02438-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08016
[Journal Article] Regulatory T cells are increased and correlate with mast cells in eosinophilic esophagitis.2024
- Author(s)
  Chen J, Oshima T, Tomita T, Fukui H, Shinzaki S.
- Journal Title
  
  J Neurogastroenterol Motil
  
  Volume: 30 Issue: 1 Pages: 29-37
- DOI
  10.5056/jnm23040
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08016
[Journal Article] Effect of Bifidobacterium bifidum G9-1 on the intestinal environment and diarrhea-predominant irritable bowel syndrome (IBS-D)-like symptoms in patients with quiescent Crohn's disease: A prospective pilot study.2023
- Author(s)
  Tomita T, Fukui H, Okugawa T, Nakanishi T, Mieno M, Nakai K, Eda H, Kitayama Y, Oshima T, Shinzaki S, Miwa H.
- Journal Title
  
  J Clin Med
  
  Volume: 12 Issue: 10 Pages: 3368-3368
- DOI
  10.3390/jcm12103368
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08016, KAKENHI-PROJECT-23K25219
[Journal Article] Diarrhea-predominat irritable bowel syndrome-like symptoms in patients with quiescent Crohn's disease: Comprehensive analysis of clinical features and intestinal environment including the gut microbiome, organic acids, and intestinal permeability.2023
- Author(s)
  Tomita T, Fukui H, Morishita D, Maeda A, Makizaki Y, Tanaka Y, Ohno H, Oshima T, Miwa H.
- Journal Title
  
  J Neurogastroenterol Motil
  
  Volume: 29 Issue: 1 Pages: 102-112
- DOI
  10.5056/jnm22027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08016
[Journal Article] Reg family proteins contribute to inflammation and pancreatic stellate cells activation in chronic pancreatitis2023
- Author(s)
  Chen Wenting、Imasaka Mai、Lee Miyu、Fukui Hirokazu、Nishiura Hiroshi、Ohmuraya Masaki
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 12201-12201
- DOI
  10.1038/s41598-023-39178-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K20666, KAKENHI-PROJECT-22K07997, KAKENHI-PROJECT-21K08016
[Journal Article] Non-cardiac chest pain in Japan: prevalence, impact, and consultation behavior - a population-based study2023
- Author(s)
  Chen J, Oshima T, Kondo T, Tomita T, Fukui H, Shinzaki S, Miwa H.
- Journal Title
  
  J Neurogastroenterol Motil.
  
  Volume: 29 Issue: 4 Pages: 446-454
- DOI
  10.5056/jnm22184
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08066, KAKENHI-PROJECT-21K08016
[Journal Article] Esophageal mucosal permeability as a surrogate measure of cure in eosinophilic esophagitis.2022
- Author(s)
  Chen J, Oshima T, Huang X, Tomita T, Fukui H, Miwa H.
- Journal Title
  
  J Clin Med
  
  Volume: 11 Issue: 14 Pages: 4246-4246
- DOI
  10.3390/jcm11144246
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08016
[Journal Article] Efficacy of serotonin type 3 receptor antagonist ramosetron on diarrhea-predominant irritable bowel syndrome (IBS-D)-like symptoms in patients with quiescent inflammatory bowel disease: A randomized, double-blind, placebo-controlled trial.2022
- Author(s)
  Tomita T, Fukui H, Morishita D, Mori S, Oshima T, Shinzaki S, Miwa H.
- Journal Title
  
  J Clin Med
  
  Volume: 11 Issue: 23 Pages: 6822-6822
- DOI
  10.3390/jcm11236882
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08016
[Journal Article] Yokukansan suppresses gastric hypersensitivity and eosinophil-associated mcroinflammation in rats with functional dyspepsia.2022
- Author(s)
  Duan S, Imamura N, Kondo T, Kanda H, Kogure Y, Okugawa T, Fukushima M, Tomita T, Oshima T, Fukui H, Noguchi K, Dai Y, Miwa H.
- Journal Title
  
  J Neurogastroenterol Motil
  
  Volume: 28 Issue: 2 Pages: 255-264
- DOI
  10.5056/jnm21204
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08016, KAKENHI-PROJECT-20K07770
[Journal Article] Gastric xanthelasma, microsatellite instability and methylation of tumor suppressor genes in the gastric mucosa: correlation and comparison as a predictive marker for the development of synchronous/metachronous gastric cancer2022
- Author(s)
  Fukushima M, Fukui H, Watari J, Ito C, Hara K, Eda H, Tomita T, Oshima T, Miwa H.
- Journal Title
  
  J Clin Med
  
  Volume: 11 Issue: 1 Pages: 9-9
- DOI
  10.3390/jcm11010009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08016
[Journal Article] Duodenal cholinergic tuft cell number is increased in functional dyspepsia.2022
- Author(s)
  Huang X, Oshima T, Akiba Y, Yoshimoto T, Chen J, Taki M, Tomita T, Fukui H, Kaunitz JD, Miwa H.
- Journal Title
  
  Neurogastroenterol Motil
  
  Volume: 34 Issue: 10
- DOI
  10.1111/nmo.14378
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08016
[Journal Article] Microinflammation in the intestinal mucosa and symptoms of irritable bowel syndrome.2022
- Author(s)
  Yoshimoto T, Oshima T, Huang X, Tomita T, Fukui H, Miwa H.
- Journal Title
  
  J Gastroenterol
  
  Volume: 57 Issue: 2 Pages: 62-69
- DOI
  10.1007/s00535-021-01838-4
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08016
[Journal Article] Acid increases PGE<sub>2</sub> in the duodenal mucosa in rats2022
- Author(s)
  Fujimura T, Kondo T, Kobayashi K, Duan S, Kanda H, Kono T, Fukushima M, Tomita T, Oshima T, Fukui H, Fujii Y, Konemura T, Okada H, Yamanaka H, Dai Y, Noguchi K, Miwa H.
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 70 Issue: 1 Pages: 28-32
- DOI
  10.3164/jcbn.21-59
- NAID
  130008139100
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08016
[Journal Article] The potential role of REG family proteins in inflammatory and inflammation-associated diseases of the gastrointestinal tract2021
- Author(s)
  Sun C, Wang X, Hui Y, Fukui H, Wang B, Miwa H.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 22 Issue: 13 Pages: 7196-7196
- DOI
  10.3390/ijms22137196
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08016
[Journal Article] Senna Versus Magnesium Oxide for the Treatment of Chronic Constipation: A Randomized, Placebo-Controlled Trial.2021
- Author(s)
  Morishita D, Tomita T, Mori S, Kimura T, Oshima T, Fukui H, Miwa H.
- Journal Title
  
  Am J Gastroenterol.
  
  Volume: 116 Issue: 1 Pages: 152-161
- DOI
  10.14309/ajg.0000000000000942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07986, KAKENHI-PROJECT-21K08016
[Journal Article] Effect of a high-fat diet on the small-intestinal environment and mucosal integrity in the gut-liver axis2021
- Author(s)
  Nakanishi T, Fukui H, Wang X, Nishiumi S, Yokota H, Makizaki Y, Tanaka Y, Ohno H, Tomita T, Oshima T, Miwa H.
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 11 Pages: 3168-3168
- DOI
  10.3390/cells10113168
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08016
[Journal Article] Probiotic Bifidobacterium bifidum G9-1 has a preventive effect on the acceleration of colonic permeability and M1 macrophage population in maternally separated rats.2021
- Author(s)
  Wang X, Fukui H, Ran Y, Xu X, Ebisutani N, Nakanishi T, Tanaka Y, Maeda A, Makizaki Y, Tomita T, Oshima T, Miwa H.
- Journal Title
  
  Biomedicines
  
  Volume: 9 Issue: 6 Pages: 641-641
- DOI
  10.3390/biomedicines9060641
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08016
[Journal Article] Glutamine blocks interleukin-13-induced intestinal epithelial barrier dysfunction2021
- Author(s)
  Li M, Oshima T, Ito C, Yamada M, Tomita T, Fukui H, Miwa H.
- Journal Title
  
  Digestion
  
  Volume: 102 Issue: 2 Pages: 170-179
- DOI
  10.1159/000502953
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08016
[Journal Article] Role of the b-catenin/REG Ia axis in the proliferation of sessile serrated adenoma/polyps associated with Fusobacterium nucleatum2021
- Author(s)
  Nishimura H, Fukui H, Wang X, Ebisutani N, Nakanishi T, Tomita T, Oshima T, Hirota S, Miwa H.
- Journal Title
  
  Pathogens
  
  Volume: 10 Issue: 4 Pages: 434-434
- DOI
  10.3390/pathogens10040434
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08016
[Journal Article] Eosinophil-associated microinflammation in the gastroduodenal tract contributes to gastric hypersensitivity in a rat model of early-life adversity2021
- Author(s)
  Duan Shaoqi、Kondo Takashi、Miwa Hiroto、Yang Yanjing、Wang Shenglan、Kanda Hirosato、Kogure Yoko、Imamura Nobuko、Fujimura Tadahiro、Kono Tomoaki、Fukushima Masashi、Tozawa Katsuyuki、Tomita Toshihiko、Oshima Tadayuki、Fukui Hirokazu、Yamamoto Satoshi、Noguchi Koichi、Dai Yi
- Journal Title
  
  American Journal of Physiology-Gastrointestinal and Liver Physiology
  
  Volume: 320 Issue: 2 Pages: G206-G216
- DOI
  10.1152/ajpgi.00313.2020
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07770, KAKENHI-PROJECT-18K08019, KAKENHI-PROJECT-21K08016
[Journal Article] Vitamin D receptor is overexpressed in the duodenum of patients with irritable bowel syndrome2021
- Author(s)
  Miura K, Oshima T, Ito C, Horikawa T, Yamada M, Tomita T, Fukui H, Miwa H.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 36 Issue: 4 Pages: 951-958
- DOI
  10.1111/jgh.15225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08016
[Journal Article] Butyrate alleviates cytokine-induced barrier dysfunction by modifying caudin-2 levels2021
- Author(s)
  Huang X, Oshima T, Tomita T, Fukui H, Miwa H.
- Journal Title
  
  Biology-Basel
  
  Volume: 10 Issue: 3 Pages: 205-205
- DOI
  10.3390/biology10030205
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08016
[Journal Article] Decreased Colonic Guanylin/Uroguanylin Expression and Dried Stool Property in Mice With Social Defeat Stress.2020
- Author(s)
  Ebisutani N, Fukui H, Nishimura H, Nakanishi T, Morimoto K, Itou S, Nakamura A, Masutani M, Hori M, Tomita T, Oshima T, Kasahara E, Sekiyama A, Miwa H.
- Journal Title
  
  Front Physiol.
  
  Volume: 14 Pages: 599582-599582
- DOI
  10.3389/fphys.2020.599582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07986
[Journal Article] Lubiprostone induces claudin-1 and protects intestinal barrier function2020
- Author(s)
  Nishii N, Oshima T, Li M, Eda H, Nakamura K, Tamura A, Ogawa T, Yamasaki T, Kondo T, Kono T, Tozawa K, Tomita T, Fukui H, Miwa H.
- Journal Title
  
  Pharmacology
  
  Volume: 105 Issue: 1-2 Pages: 102-108
- DOI
  10.1159/000503054
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Journal Article] Alteration of Colonic Mucosal Permeability during Antibiotic-Induced Dysbiosis.2020
- Author(s)
  Ran Y, Fukui H, Xu X, Wang X, Ebisutani N, Tanaka Y, Maeda A, Makizaki Y, Ohno H, Kondo T, Kono T, Tozawa K, Tomita T, Oshima T, Miwa H.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 21 Issue: 17 Pages: 6108-6108
- DOI
  10.3390/ijms21176108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07986
[Journal Article] Phosphorylated STAT3 expression linked to SOCS3 methylation is associated with proliferative ability of gastric mucosa in patients with early gastric cancer2020
- Author(s)
  Fukui H, Watari J, Zhang X, Ran Y, Tomita T, Oshima T, Hirota S, Miwa H.
- Journal Title
  
  Oncol Lett
  
  Volume: 19 Pages: 3542-3550
- DOI
  10.3892/ol.2020.11462
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Journal Article] DNA methylation silencing of microRNA gene methylator in the precancerous background mucosa with and without gastric cancer: Analysis of the effects of H. pylori eradication and long-term aspirin use2019
- Author(s)
  Watari J, Ito C, Shimoda T, Tomita T, Oshima T, Fukui H, Das KM, Miwa H.
- Journal Title
  
  Sci Rep
  
  Volume: 9 Issue: 1 Pages: 12559-12559
- DOI
  10.1038/s41598-019-49069-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Journal Article] The Link Between Type III Reg and STAT3-Associated Cytokines in Inflamed Colonic Tissues2019
- Author(s)
  Xin Xu , Hirokazu Fukui , Ying Ran , Xuan Wang , Yoshihito Inoue , Nobuhiko Ebisudani, Heihachiro Nishimura, Toshihiko Tomita , Tadayuki Oshima , Jiro Watari , Hiroshi Kiyama , Hiroto Miwa
- Journal Title
  
  Mediators　Inflamm
  
  Volume: 6 Pages: 7859460-7859460
- DOI
  10.1155/2019/7859460
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07986, KAKENHI-PROJECT-17K09363
[Journal Article] Colonic M1 macrophage is associated with the prolongation of gastrointestinal motility and obesity in mice treated with vancomycin2019
- Author(s)
  Inoue Y, Fukui H, Xu X, Ran Y, Tomita T, Oshima T, Watari J, Miwa H.
- Journal Title
  
  Mol Med Rep
  
  Volume: 19 Pages: 2591-2598
- DOI
  10.3892/mmr.2019.9920
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Journal Article] Chenodeoxycholic acid releases proinflammatory cytokines from small intestinal epithelial cells through the farnesoid X receptor2019
- Author(s)
  Horikawa T, Oshima T, Li M, Kitayama Y, Eda H, Nakamura K, Tamura A, Ogawa T, Yamasaki T, Okugawa T, Kondo T, Kono T, Tozawa K, Tomita T, Fukui H, Watari J, Miwa H.
- Journal Title
  
  Digestion
  
  Volume: 100 Issue: 4 Pages: 286-294
- DOI
  10.1159/000496687
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Journal Article] Alteration of GLP-1/GPR43 expression and gastrointestinal motility in dysbiotic mice treated with vancomycin.2019
- Author(s)
  Xu X, Fukui H, Ran Y, Tomita T, Oshima T, Watari J, Miwa H.
- Journal Title
  
  Sci Rep
  
  Volume: 9 Issue: 1 Pages: 4381-4381
- DOI
  10.1038/s41598-019-40978-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363, KAKENHI-PROJECT-18K07986
[Journal Article] A randomized double-blind placebo-controlled trial on the effect of magnesium oxide in patients with chronic constipation2019
- Author(s)
  Mori S, Tomita T, Fujimura K, Asano H, Ogawa T, Yamasaki T, Kondo T, Kono T, Tozawa K, Oshima T, Fukui H, Kimura T, Watari J, Miwa H.
- Journal Title
  
  J Neurogastroenterol Motil
  
  Volume: 25 Issue: 4 Pages: 563-575
- DOI
  10.5056/jnm18194
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09363
[Journal Article] Duodenal low-grade inflammation and expression of tight junction proteins in functional dyspepsia2019
- Author(s)
  Taki M, Oshima T, Li M, Sei H, Tozawa K, Tomita T, Fukui H, Watari J, Miwa H
- Journal Title
  
  Neurogastroenterology & motility
  
  Volume: Epub ahead Issue: 10
- DOI
  10.1111/nmo.13576
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09297, KAKENHI-PROJECT-17K09363
[Journal Article] Recent understanding of the pathophysiology of functional dyspepsia: role of the duodenum as the pathogenic center2019
- Author(s)
  Miwa H, Oshima T, Tomita T, Fukui H, Kondo T, Yamasaki T, Watari J
- Journal Title
  
  Journal of gastroenterology
  
  Volume: 54 Issue: 4 Pages: 305-311
- DOI
  10.1007/s00535-019-01550-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09297
[Journal Article] Role of gut microbiota-gut hormone axis in the pathophysiology of functional gastrointestinal disorders.2018
- Author(s)
  Fukui H, Xu X, Miwa H.
- Journal Title
  
  J Neurogastroenterol Motil
  
  Volume: 24 Issue: 3 Pages: 367-386
- DOI
  10.5056/jnm18071
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Journal Article] Sex differences in associations among metabolic syndrome, obesity, related biomarkers, and colorectal adenomatous polyp risk in a Japanese population2018
- Author(s)
  Nakai K, Watari J, Tozawa K, Tamura A, Hara K, Yamasaki T, Kondo T, Kono T, Tomita T, Ohda Y, Oshima T, Fukui H, Sakurai J, Kim Y, Hayakawa Y, Fujisawa T, Morimoto T, Miwa H.
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 63 Issue: 2 Pages: 154-163
- DOI
  10.3164/jcbn.18-11
- NAID
  130007479962
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09363
[Journal Article] Filaggrin and tight junction proteins are crucial for IL-13-mediated esophageal barrier dysfunction2018
- Author(s)
  Wu L, Oshima T, Li M, Tomita T, Fukui H, Watari J, Miwa H.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 315 Issue: 3 Pages: G341-G350
- DOI
  10.1152/ajpgi.00404.2017
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363, KAKENHI-PROJECT-16K09297
[Journal Article] Effect of probiotic Bifidobacterium bifidum G9-1 on the relationship between gut microbiota profile and stress sensitivity in maternally separated rats2018
- Author(s)
  Fukui H, Oshima T, Tanaka Y, Oikawa Y, Makizaki Y, Ohno H, Tomita T, Watari J, Miwa H.
- Journal Title
  
  Sci Rep
  
  Volume: 8 Issue: 1 Pages: 12384-12384
- DOI
  10.1038/s41598-018-30943-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09363
[Journal Article] Long-term effects of H. pylori eradication on epigenetic alterations related to gastric carcinogenesis2018
- Author(s)
  Michigami Y, Watari J, Ito C, Nakai K, Yamasaki T, Kondo T, Kono T, Tozawa K, Tomita T, Oshima T, Fukui H, Morimoto T, Das KM, Miwa H.
- Journal Title
  
  Sci Rep
  
  Volume: 8 Issue: 1 Pages: 14369-14369
- DOI
  10.1038/s41598-018-32717-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Journal Article] Association between gastrointestinal motility and macrophage/mast cell distribution in mice during the healing stage after DSS-induced colitis2018
- Author(s)
  Kodani M, Fukui H, Tomita T, Oshima T, Watari J, Miwa H.
- Journal Title
  
  Mol Med Rep
  
  Volume: 17 Pages: 8167-8172
- DOI
  10.3892/mmr.2018.8926
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09363, KAKENHI-PROJECT-18K07986
[Journal Article] Magnitude and direction of the association between Clostridium difficile infection and proton pump inhibitors in adults and pediatric patients: a systematic review and meta-analysis.2018
- Author(s)
  Oshima T, Wu L, Li M, Fukui H, Watari J, Miwa H.
- Journal Title
  
  J Gastroenterol
  
  Volume: 53 Issue: 1 Pages: 84-94
- DOI
  10.1007/s00535-017-1369-3
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Journal Article] Adenosine triphosphate induces P2Y2 activation and IL-8 release in human esophageal epithelial cells2017
- Author(s)
  Wu L, Oshima T, Fukui H, Watari J, Miwa H.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 32 Issue: 7 Pages: 1341-1347
- DOI
  10.1111/jgh.13672
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Journal Article] Involvement of gut microbiota in the association between gastrointestinal motility and 5-HT expression/M2 macrophage behavior in the gastrointestinal tract2017
- Author(s)
  Yang M, Fukui H, Eda H, Kitayama Y, Hara K, Kodani M, Tomita T, Oshima T, Watari J, Miwa H
- Journal Title
  
  Mol Med Rep
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460953
[Journal Article] Effect of long-term aspirin use on molecular alterations in precancerous gastric mucosa in patients with and without gastric cancer2017
- Author(s)
  Michigami Y, Watari J, Ito C, Hara K, Yamasaki T, Kondo T, Kono T, Tozawa K, Tomita T, Oshima T, Fukui H, Morimoto T, Das KM, Miwa H.
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 13384-13384
- DOI
  10.1038/s41598-017-13842-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Journal Article] Acotiamide improves stress-induced gastric accommodation2017
- Author(s)
  Ikeo K, Oshima T, Sei H, Kondo T, Fukui H, Watari J, Miwa H.
- Journal Title
  
  Neurogastroenterol Motil
  
  Volume: 29 Issue: 4
- DOI
  10.1111/nmo.12991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09363
[Journal Article] Effect of vonoprazan, a potassium-competitive acid blocker, on the 13C-urea breath test in Helicobacter pylori-positive patients2017
- Author(s)
  Takimoto M, Tomita T, Yamasaki T, Fukui S, Taki M, Okugawa T, Kondo T, Kono T, Tozawa K, Arai E, Ohda Y, Oshima T, Fukui H, Watari J, Miwa H.
- Journal Title
  
  Dig Dis Sci
  
  Volume: 62 Issue: 3 Pages: 739-745
- DOI
  10.1007/s10620-016-4439-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09363
[Journal Article] Intravenous corticotropin-releasing hormone administration increases esophageal electrical sensitivity in healthy individuals2017
- Author(s)
  Yamasaki T, Tomita T, Takimoto M, Kondo T, Tozawa K, Ohda Y, Oshima T, Fukui H, Watari J, Miwa H.
- Journal Title
  
  Neurogastroenterol Motil
  
  Volume: 23 Issue: 4 Pages: 526-532
- DOI
  10.5056/jnm17067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09363
[Journal Article] A novel prostanoid EP1 receptor antagonist, ONO-8539, reduces acid-induced heartburn symptoms in healthy male volunteers: a randomized clinical trial.2017
- Author(s)
  Kondo T, Sei H, Yamasaki T, Tomita T, Ohda Y, Oshima T, Fukui H, Watari J, Miwa H.
- Journal Title
  
  J Gastroenterol
  
  Volume: 52 Issue: 10 Pages: 1081-1089
- DOI
  10.1007/s00535-017-1308-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09363
[Journal Article] A double-blind placebo controlled study of acotiamide hydrochloride for efficacy on gastrointestinal motility of patients with functional dyspepsia2017
- Author(s)
  Nakamura K, Tomita T, Oshima T, Asano H, Yamasaki T, Okugawa T, Kondo T, Kono T, Tozawa K, Ohda Y, Fukui H, Kazuhito F, Hirota S, Watari J, Miwa H.
- Journal Title
  
  J Gastroenterol
  
  Volume: 52 Issue: 5 Pages: 602-610
- DOI
  10.1007/s00535-016-1260-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09363
[Journal Article] Involvement of gut microbiota in the association between GLP-1/GLP-1 receptor expression and gastrointestinal motility2017
- Author(s)
  Yang M, Fukui H, Eda H, Xu X, Kitayama Y, Hara K, Kodani M, Tomita T, Oshima T, Watari J, Miwa H
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 312 Issue: 4 Pages: G367-G373
- DOI
  10.1152/ajpgi.00232.2016
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460953, KAKENHI-PROJECT-17K09363
[Journal Article] Prevalence of gastric motility disorders in patients with functional dyspepsia2017
- Author(s)
  Asano H, Tomita T, Nakamura K, Yamasaki T, Okugawa T, Kondo T, Kono T, Tozawa K, Ohda Y, Oshima T, Fukui H, Fukushima K, Hirota S, Watari J, Miwa H.
- Journal Title
  
  J Neurogastroenterol Motil
  
  Volume: 23 Issue: 3 Pages: 392-399
- DOI
  10.5056/jnm16173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09363
[Journal Article] Effect of Helicobacter pylori infection on the link between GLP-1 expression and motility of the gastrointestinal tract2017
- Author(s)
  Eda H, Fukui H, Uchiyama R, Kitayama Y, Hara K, Yang M, Kodani M, Tomita T, Oshima T, Watari J, Tsutsui H, Miwa H
- Journal Title
  
  PLOS One
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460953
[Journal Article] Genetic instability, CpG island methylator phenotype and proliferative activity are distinct differences between diminutive and small tubular adenoma of the colorectum2017
- Author(s)
  Nando Y, Watari J, Hara K, Yamasaki T, Okugawa T, Kondo T, Kono T, Tozawa K, Tomita T, Ohda Y, Oshima T, Fukui H, Matsubara N, Tomita N, Hirota S, Miwa H.
- Journal Title
  
  Hum Pathol
  
  Volume: 60 Pages: 37-45
- DOI
  10.1016/j.humpath.2016.09.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09363
[Journal Article] Involvement of gut microbiota in the association between gastrointestinal motility and 5-HT expression/M2 macrophage behavior in the gastrointestinal tract2017
- Author(s)
  Yang M, Fukui H, Eda H, Kitayama Y, Hara K, Kodani M, Tomita T, Oshima T, Watari J, Miwa H.
- Journal Title
  
  Mol Med Rep
  
  Volume: 16 Issue: 3 Pages: 3482-3488
- DOI
  10.3892/mmr.2017.6955
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Journal Article] Claudin-2 expression is upregulated in the ileum of diarrhea predominant irritable bowel syndrome patients2017
- Author(s)
  Ishimoto H, Oshima T, Sei H, Yamasaki T, Kondo T, Tozawa K, Tomita T, Ohda Y, Fukui H, Watari J, Miwa H.
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 60 Issue: 2 Pages: 146-150
- DOI
  10.3164/jcbn.16-92
- NAID
  130005398540
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09363
[Journal Article] Effect of Helicobacter pylori infection on the link between GLP-1 expression and motility of the gastrointestinal tract2017
- Author(s)
  Eda H, Fukui H, Uchiyama R, Kitayama Y, Hara K, Yang M, Kodani M, Tomita T, Oshima T, Watari J, Tsutsui H, Miwa H.
- Journal Title
  
  PLOS One
  
  Volume: 12 Issue: 5 Pages: e0177232-e0177232
- DOI
  10.1371/journal.pone.0177232
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Journal Article] Esophageal Epithelial-Derived IL-33 Is Upregulated in Patients with Heartburn2016
- Author(s)
  Hiroo Sei, Tadayuki Oshima, Jing Shan, Liping Wu, Takahisa Yamasaki, Takuya Okugawa, Takashi Kondo, Toshihiko Tomita, Hirokazu Fukui, Jiro Watari, Hiroto Miwa
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 4 Pages: e0154234-e0154234
- DOI
  10.1371/journal.pone.0154234
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460939
[Journal Article] Serotonin disrupts esophageal mucosal integrity: an investigation using a stratified squamous epithelial model2016
- Author(s)
  Liping Wu, Tadayuki Oshima, Toshihiko Tomita, Yoshio Ohda, Hirokazu Fukui, Jiro Watari, Hiroto Miwa
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 未
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460939
[Journal Article] Role of regenerating gene I in claudin expression and barrier function in the small intestine2016
- Author(s)
  Kitayama Y, Fukui H, Hara K, Eda H, Kodani M, Yang M, Sun C, Yamagishi H, Tomita T, Oshima T, Watari J, Takasawa S, Miwa H.
- Journal Title
  
  Transl Res
  
  Volume: 173 Pages: 92-100
- DOI
  10.1016/j.trsl.2016.03.007
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460953
[Journal Article] Interferon gamma-induced nuclear interleukin-33 potentiates the release of esophageal epithelial derived cytokines2015
- Author(s)
  Jing Shan, Tadayuki Oshima, Liping Wu, Hirokazu Fukui, Jiro Watari, Hiroto Miwa
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 3 Pages: e0151701-e0151701
- DOI
  10.1371/journal.pone.0151701
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460939
[Journal Article] FGF9 from cancer-associated fibroblasts is a possible mediator of invasion and anti-apoptosis of gastric cancer cells2015
- Author(s)
  Sun C, Fukui H, Hara K, Zhang X, Kitayama Y, Eda H, Tomita T, Oshima T, Kikuchi S, Watari J, Sasako M, Miwa H
- Journal Title
  
  BMC Cancer
  
  Volume: 15 Issue: 1 Pages: 333-333
- DOI
  10.1186/s12885-015-1353-3
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460953
[Journal Article] Effect of Effect of REG Ia protein on angiogenesis in gastric cancer tissuesREG I protein on angiogenesis in gastric cancer tissues2015
- Author(s)
  Hara K, Fukui H, Sun C, Kitayama Y, Eda H, Yamasaki T, Kondo T, Tomita T, Oshima T, Watari J, Fujimori T, Miwa H
- Journal Title
  
  Oncol Rep
  
  Volume: 33 Issue: 5 Pages: 2183-2189
- DOI
  10.3892/or.2015.3878
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460953
[Journal Article] Expression of Reg family genes in the gastrointestinal tract of mice treated with indomethacin2015
- Author(s)
  Sun C, Fukui H, Hara K, Kitayama Y, Eda H, Yang M, Yamagishi H, Tomita T, Oshima T, Watari J, Takasawa S, Chiba T, Miwa H
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 308 Issue: 9 Pages: G736-G744
- DOI
  10.1152/ajpgi.00362.2014
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460953
[Journal Article] Epithelial-derived nuclear IL-33 aggravates inflammation in the pathogenesis of reflux esophagitis.2015
- Author(s)
  Shan J, Oshima T, Muto T, Yasuda K, Fukui H, Watari J, Nakanishi K, Miwa H.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 40 Issue: 4 Pages: 414-423
- DOI
  10.1007/s00535-014-0988-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460521, KAKENHI-PROJECT-25460939
[Journal Article] IL-4 induces columnar like differentiation of esophageal squamous epithelium through JAK/PI3K pathway: possible role in pathogenesis of Barrett's esophagus.2014
- Author(s)
  Shan J, Oshima T, Farre R, Fukui H, Watari J, Miwa H.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460953
[Journal Article] IL-22 produced by cancer-associated fibroblasts promotes gastric cancer cell invasion via STAT3 and ERK signaling.2014
- Author(s)
  Fukui H, Zhang X, Sun C, Hara K, Kikuchi S, Yamasaki T, Kondo T, Tomita T, Oshima T, Watari J, Imura J, Fujimori T, Sasako M, Miwa H
- Journal Title
  
  Br J Cancer
  
  Volume: 111 Issue: 4 Pages: 183-490
- DOI
  10.1038/bjc.2014.336
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460413, KAKENHI-PROJECT-25460466, KAKENHI-PROJECT-26460953
[Journal Article] A Randomized, double-blind, placebo-controlled study of rebamipide for gastric mucosal injury taking aspirin with or without clopidogrel.2014
- Author(s)
  Tozawa K, Oshima T, Okugawa T, Ogawa T, Ohda Y, Tomita T, Hida N, Fukui H, Hori K, Watari J, Nakamura S, Miwa H.
- Journal Title
  
  Dig Dis Sci
  
  Volume: 59 Pages: 1885-1890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460953
[Journal Article] Gastric xanthelasma may be a warning sign for the presence of early gastric cancer.2014
- Author(s)
  Sekikawa A, Fukui H, Maruo T, Tsumura T, Kanesaka T, Okabe Y, Osaki Y.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 29 Issue: 5 Pages: 951-956
- DOI
  10.1111/jgh.12512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460953
[Journal Article] Diabetes mellitus increases the risk of early gastric cancer development.2014
- Author(s)
  Sekikawa A, Fukui H, Maruo T, Tsumura T, Okabe Y, Osaki Y.
- Journal Title
  
  Eur J Cancer
  
  Volume: 50 Issue: 12 Pages: 2065-2071
- DOI
  10.1016/j.ejca.2014.05.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460953
[Journal Article] Acidic deoxycholic acid and chenodeoxycholic acid induce IL-8 production through p38 MAPK and PKA in a squamous epithelial model2013
- Author(s)
  Shan J, Oshima T, Fukui H, Watari J, Miwa
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 28 Pages: 823-828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590929
[Journal Article] Overexpression of regenerating gene Iαappears to reflect aberration of crypt cell compartmentalization in sessile serrated adenoma/polyps of the colon2013
- Author(s)
  Okamoto K, Fujimori T, Yamaguchi T, Ichikawa K, Tomita S, Imura J, Ohkura Y, Yao T, Fujii S, Kusaka T, Sekikawa A, Fukui H, Chiba T, Kato H, Mitomi H
- Journal Title
  
  Diagn Pathol
  
  Volume: 8 Pages: 187-187
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590929
[Journal Article] Overexpression of regenerating gene Iα appears to reflect aberration of crypt cell compartmentalization in sessile serrated adenoma/polyp of the colon2013
- Author(s)
  Okamoto K, Fujimori T (16人中2番目)
- Journal Title
  
  Diagnostic Pathology
  
  Volume: 8 Issue: 1 Pages: 187-187
- DOI
  10.1186/1746-1596-8-187
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590410, KAKENHI-PROJECT-23590929, KAKENHI-PROJECT-25460413, KAKENHI-PROJECT-25460420
[Journal Article] Down-regulation of claudin-18 is associated with the proliferative and invasive potential of gastric cancer at the invasive front2013
- Author(s)
  Oshima T, Shan J, Okugawa T, Chen X, Hori K, Tomita T, Fukui H, Watari J, Miwa H
- Journal Title
  
  PLoS One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590929
[Journal Article] REG Iαis a biomarker for predicting response to chemotherapy with S-1 puls cisplatin in patients with unresectable stage IV gastric cancer2013
- Author(s)
  Sekikawa A, Fukui H, Zhang X, Maruo T, Tsumura T, Okabe Y, Wakasa T, Osaki Y, Chiba T, Tomita T, Oshima T, Watari J, Miwa H
- Journal Title
  
  Br J Cancer
  
  Volume: 108 Pages: 395-401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590929
[Journal Article] Down-regulation of claudin-3 is associated with proliferative potential in early gastric cancers2012
- Author(s)
  Okugawa T, Oshima T, Chen X, Hori K, Tomita T, Fukui H, Watari J, Miwa H
- Journal Title
  
  Dig Dis Sci
  
  Volume: 57 Pages: 1562-1567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590929
[Journal Article] Regenerating gene (REG) 1 alpha promotes pannus progression in patients with rheumatoid arthritis2012
- Author(s)
  Fujishiro M, Nozawa K, Kawasaki M, Yamaguchi A, Iwabuchi K, Yanagida M, Suzuki F, Miyazawa K, Fukui H, Kaneko K, Ogawa H, Takamori K, Takasaki Y, Sekigawa I
- Journal Title
  
  Mod Rheumatol
  
  Volume: 22 Pages: 228-237
- NAID
  10030615061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590929
[Journal Article] Bile salts disrupt human esophageal squamous epithelial barrier function by modulating tight junction proteins2012
- Author(s)
  Chen X, Oshima T, Shan J, Fukui H, Watari J, Miwa H
- Journal Title
  
  Am J Physiol
  
  Volume: 303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590929
[Journal Article] Trypsin impaired epithelial barrier function and induced IL-8 secretion through basolateral PAR-2: a lesson from a stratified squamous epithelial model2012
- Author(s)
  Shan J, Oshima T, Chen X, Fukui H, Watari J, Miwa H
- Journal Title
  
  Am J Physiol
  
  Volume: 303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590929
[Journal Article] Immunohistochemical analysis of REG I expression in ulcerative colitis-associated neoplastic lesions.2011
- Author(s)
  Tanaka H, Fukui H, Fujii S, Sekikawa A, Yamagishi H, Ichikawa K, Tomita S, Imura J, Yasuda Y, Chiba T, Fujimori T
- Journal Title
  
  Digestion 83
  
  Pages: 204-209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590747
[Journal Article] Acidic bile salts modulate the squamous epithelial barrier function by modulating tight junction proteins2011
- Author(s)
  Chen X, Oshima T, Tomita T, Fukui H, Watari J, Matsumoto T, Miwa H
- Journal Title
  
  Am J Physiol
  
  Volume: 301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590929
[Journal Article] DMBT1 is a novel gene induced by IL-22 in ulcerative colitis2011
- Author(s)
  Fukui H, Sekikawa A, Tanaka H, Fujimori Y, Katake Y, Fujii S, Ichikawa K, Tomita S, Imura J, Chiba T, Fujimori T
- Journal Title
  
  Inflam Bowel Dis
  
  Volume: 17 Pages: 1177-1188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590929
[Journal Article] Expression of -catenin and REG I in relation to cell proliferative ability in salivary gland tumors.2010
- Author(s)
  Hakata Y, Fukui H, Sekikawa A, Yamagishi H, Ichikawa K, Tomita S, Imura J, Kawamata H, Imai Y, Fujimori T
- Journal Title
  
  Exp Ther Med 1
  
  Pages: 437-443
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590747
[Journal Article] GRO promotes invasion of colorectal cancer cells.2010
- Author(s)
  Ogata H, Sekikawa A, Fukui H
- Journal Title
  
  Oncol Rep 24
  
  Pages: 1479-1486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590747
[Journal Article] Involvement of the IL-22/REG I axis in ulcerative colitis.2010
- Author(s)
  Sekikawa A, Fukui H, Suzuki K, Karibe T,Fujii S, Ichikawa K, Tomita S, Imura J, Shiratori K, Chiba T, Fujimori T
- Journal Title
  
  Lab Invest 90
  
  Pages: 496-505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590747
[Journal Article] Role of Necl-5 in the Pathophysiology of colorectal lesions induced by dimethylhydrazine and/or dextran sodium sulfate.2009
- Author(s)
  Abe A, Fukui H, Fujimori T
- Journal Title
  
  J Pathol 217
  
  Pages: 42-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590747
[Journal Article] Expression profile of REG family proteins, REG I and REG IV in advanced gastric cancer : Comparison with mucin phenotype and prognostic markers.2009
- Author(s)
  Yamagishi H, Fukui H, Sekikawa A
- Journal Title
  
  Modern Pathol 22
  
  Pages: 906-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590747
[Journal Article] Involvement of REG I protein in the regeneration of ductal epithelial cells in the minor salivary glands of patients with Sjogren's syndrome.2009
- Author(s)
  Kimura T, Fukui H, Sekikawa A
- Journal Title
  
  Clin Exp Immunol 155
  
  Pages: 16-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590747
[Journal Article] EXTL3 promoter methylation down-regulates EXTL3 and heparan sulphate expression in mucinous colorectal cancers.2008
- Author(s)
  Karibe T, Fukui H, Sekikawa A, Shiratori K, Fujimori T
- Journal Title
  
  J Pathol 216
  
  Pages: 32-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590747
[Journal Article] Expression of SDF-1 and nuclear CX predict lymph node metastasis in colorectal cancer.2008
- Author(s)
  Yoshitake N, Fukui H, Yamagishi H, Sekikawa A, Fujii S, Tomita S, Ichikawa K, Imura J, Hiraishi H, Fujimori T
- Journal Title
  
  Br J Cancer 98
  
  Pages: 1682-1689
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590747
[Journal Article] Inhibitory effects of the cyclooxygenase-2 inhibitor, etodolac, on colitis-associated tumorigenesis in p53-deficient mice treated with dextran sulfate sodium.2008
- Author(s)
  Mukawa K, Fukui H, Fujimori T
- Journal Title
  
  Oncol Rep 19
  
  Pages: 393-399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590747
[Journal Article] REG I protein me anti-apoptotic effect of STAT3 signaling in gastric cancer cells.2008
- Author(s)
  Sekikawa A, Fukui H, Fujii S, Ichikawa K, Tomita S, Imura J, Chiba T, Fujimori T
- Journal Title
  
  Carcinogenesis 29
  
  Pages: 76-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590747
[Journal Article] Colonic expression of heme oxygenase-1 is associated with a better long-term survival in patients with colorectal cancer2007
- Author(s)
  Fukui H, Becker JC, Imai Y, Sekikawa A, Kimura T, Yamagishi H, Yoshitake N, Pohle T, Domschke W, Fujimori T.
- Journal Title
  
  Scan J Gastroenterol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590635
[Journal Article] Colonic expression of hemr oxygenase-1 is associated with a better long-term survival in patients with colorectal cancer2007
- Author(s)
  Fukui H
- Journal Title
  
  Scan J Gastroenterol (In press)
- Data Source
  KAKENHI-PROJECT-17590635
[Journal Article] Colonic expression of heme oxygenase-1 is associated with a better long-term survival in patients with colorectal cancer2007
- Author(s)
  Fukui H
- Journal Title
  
  Scan J Gastroenterol (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590635
[Journal Article] Nuclear expression of phosphorylated EGFR is associated with poor prognosis of patients with esophageal squamous cell carcinoma2007
- Author(s)
  Hoshino M, Fukui H, Ono Y, Sekikawa A, Ichikawa K, Tomita S, Imai Y, Imura J, Hiraishi H, Fujimori T.
- Journal Title
  
  Pathobiology (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590635
[Journal Article] Human papillomavirus infection is involved in the development of colonic squamous cell dysplasia in ulcerative colitis-associated carcinogenesis2007
- Author(s)
  Yoshitake N, Fukui H, Fujii S, Mukawa K, Tominaga K, Sekikawa A, Tomita S, Ichikawa K, Imura J, Nakajima K, Nezu R, Yamada Y, Yoshihara H, Hiraishi H, Fujimori T.
- Journal Title
  
  Inflam Bowel Dis (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590635
[Journal Article] Expression of the REG IV gene in ulcerative colitis2007
- Author(s)
  Nanakin A, Fukui H, Fujii S, Sekikawa A, Kanda N, Hisatsune H, Seno H, Konda Y, Fujimori T, Chiba T.
- Journal Title
  
  Lab Invest 87
  
  Pages: 304-314
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590635
[Journal Article] Magnifying pharmaco-endoscopy : response of microvessels to epinephrine stimulation in differentiated early gastric cancers2006
- Author(s)
  Fukui H
- Journal Title
  
  Gastrointest Endosc 64
  
  Pages: 40-44
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590635
[Journal Article] Gastric mucosal hyperplasia via up-regulation of gastrin induced by persistent activation of gastric innate immunity in MHC class II-deficient mice2006
- Author(s)
  Fukui T
- Journal Title
  
  Gut 55
  
  Pages: 607-615
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590635
[Journal Article] Gastric mucosal hyperplasia via up-regulation of gastrin, induced by persistent activation of gastric innate immunity in MHC class II-deficient mice2006
- Author(s)
  Fukui T, Nishio A, Okazaki K, Uza N, Ueno S, Kido M, Inoue S, Kitamura H, Kiriya K, Ohashi S, Asada M, Tamaki H, Matsuura M, Kawasaki K, Suzuki K, Uchida K, Fukui H, Nakase H, Watanabe N, Chiba T.
- Journal Title
  
  Gut 55
  
  Pages: 607-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590635
[Journal Article] Hypoxia induced by benign intestinal epithelial cells is associated with cydooxygenase-2 expression in stromal cells through AP-1-dependent pathway2006
- Author(s)
  Uenoyama Y, Seno H, Fukuda A, Sekikawa A, Nanakin A, Sawabu T, Kawada M, Kanda N, Suzuki K, Yada N, Fukui H, Chiba T.
- Journal Title
  
  Oncogene 25
  
  Pages: 3277-85
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590635
[Journal Article] Signal transducers and activators of transcription 3 activationis involved in nuclear accumulation of β-catenin in colorectal cancer2006
- Author(s)
  Kawada M, Seno H, Uenoyama Y, Sawabu T, Kanda N, Fukui H, Shimahara Y, Chiba T.
- Journal Title
  
  Cancer Res 66
  
  Pages: 2913-2917
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590635
[Journal Article] Magnifying pharmaco-endoscopy : response of microvessels to epinephrine stimulation in differentiated early gastric cancers2006
- Author(s)
  Fukui H, Shirakawa K, Nakamura T, Suzuki K, Masuyama H, Fujimori T, Hiraishi H, Terano A.
- Journal Title
  
  Gastrointest Endosc 64
  
  Pages: 40-44
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590635
[Journal Article] Involvement of cyclooxygenase-2 in gastric mucosal hypertrophy in gastrin transgenic mice2006
- Author(s)
  Kanda N, Seno H, Kawada M, Sawabu T, Uenoyama Y, Nakajima T, Konda Y, Fukui H, Takeuchi T, Chiba T.
- Journal Title
  
  Am J Physiol 290
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590635
[Journal Article] Possible role of REG la protein in ulcerative colitis and colitic cancer2005
- Author(s)
  Sekikawa A, Fukui H, Fujii S, Nanakin A, Kanda N, Uenoyama Y, Sawabu T, Hisatsune H, Kusaka T, Ueno S, Nakase H, Seno H, Fujimori T, Chiba T.
- Journal Title
  
  Gut 54
  
  Pages: 1437-1444
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590635
[Journal Article] Hes1-deficient mice show precocious differentiation of Paneth cells in the small intestine2005
- Author(s)
  Suzuki K, Fukui H, Kayahara T, Sawada M, Seno H, Fukuzawa H, Hiai H, Kageyama R, Okano H, Chiba T.
- Journal Title
  
  Biochem Biophys Res Comm 328
  
  Pages: 348-352
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590635
[Journal Article] REG la protein may function as a trophic and/or anti-apoptotic factor in the development of gastric cancer2005
- Author(s)
  Sekikawa A, Fukui H, Fujii S, Takeda J, Nanakin A, Hisatsune H, Seno H, Takasawa S, Okamoto H, Fujimori T, Chiba T.
- Journal Title
  
  Gastroenterology 128
  
  Pages: 642-653
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590635
[Journal Article] Expression of Reg 1alpha protein in human gastric cancers2004
- Author(s)
  Fukui H, Fujii S, Takeda J, Kayahara T, Sekikawa A, Nanakin A, Suzuki K, Hisatsune H, Seno H, Sawada M, Fujimori T, Chiba T.
- Journal Title
  
  Digestion 69
  
  Pages: 177-184
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590635
[Journal Article] Expression of Reg I alpha protein in human gastric cancers2004
- Author(s)
  Fukui H
- Journal Title
  
  Digestion 69
  
  Pages: 177-184
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590635
[Presentation] 寛解期炎症性腸疾患における過敏性腸症候群症状に対するラモセトロンの臨床効果2023
- Author(s)
  富田寿彦、福井広一、森下大輔、北山義隆、江田裕嗣、奥川卓也、大島忠之、新﨑信一郎、三輪洋人.
- Organizer
  第25回日本神経消化器病学会
- Data Source
  KAKENHI-PROJECT-21K08016
[Presentation] 潰瘍性大腸炎に対するトファシチニブとフィルゴチニブの短期有効性および安全性2023
- Author(s)
  422.八木聡一、福井広一、横山恵子、賀来宏司、高木康宏、池ノ内真衣子、佐藤寿行、河合幹夫、横山陽子、上小鶴孝二、富田寿彦、新﨑信一郎.
- Organizer
  第14回日本炎症性腸疾患学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08016
[Presentation] 潰瘍性大腸炎に対するUpadacitinibの短期治療成績2023
- Author(s)
  池ノ内真衣子、福井広一、横山恵子、賀来宏司、八木聡一、高木康宏、佐藤寿行、河合幹夫、上小鶴孝二、横山陽子、富田寿彦、新﨑信一郎．
- Organizer
  第14回日本炎症性腸疾患学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08016
[Presentation] 寛解期クローン病患者における過敏性腸症候群様症状と腸内環境の関連について2022
- Author(s)
  富田俊彦，福井広一，三輪洋人．
- Organizer
  第 64 回日本消化器学会大会
- Data Source
  KAKENHI-PROJECT-21K08016
[Presentation] 高脂肪食起因性脂肪肝発症における小腸内環境の変化について2022
- Author(s)
  中西貴士，福井広一，三重野将敏，鶴田晋也，岡村政道，吉原俊也，吉本崇典，中井啓介，北山嘉隆，原謙，江田裕嗣，奥川卓也，富田寿彦，大島忠之，三輪洋人
- Organizer
  第 64 回日本消化器学会大会
- Data Source
  KAKENHI-PROJECT-21K08016
[Presentation] 社会的敗北ストレスマウスにおける腸内細菌叢の変化および大腸グアニリン/ウログアニリン発現と便性状の関連2021
- Author(s)
  戎谷信彦、福井広一、三輪洋人．
- Organizer
  第 107 回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-21K08016
[Presentation] Esophageal epithelial barrier function and inflammation in eosinophilic esophagitis before and after treatment2021
- Author(s)
  Junji Chen, Tadayuki Oshima, Toshihiko Tomita, Hirokazu Fukui, Hiroto Miwa
- Organizer
  第49回日本潰瘍学会
- Data Source
  KAKENHI-PROJECT-19K08480
[Presentation] 精神的ストレスが guanylin/uroguanylin 発現と便性状に及ぼす影響について2021
- Author(s)
  戎谷信彦，福井広一，中西貴士，富田寿彦，大島忠之，三輪洋人．
- Organizer
  第 23 回日本神経消化器学会
- Data Source
  KAKENHI-PROJECT-21K08016
[Presentation] Effect of treatment on esophageal epithelial barrier function and inflammation in eosinophilic esophagitis2021
- Author(s)
  Junji Chen, Tadayuki Oshima, Keisuke Nakai, Yoshitaka Kitayama, Ken Hara, Akio Tamura, Masashi Fukushima, Takuya Okugawa, Toshihiko Tomita, Hirokazu Fukui, Hiroto Miwa
- Organizer
  Asian Pacific Digestive Week (APDW) 2021
- Data Source
  KAKENHI-PROJECT-19K08480
[Presentation] 慢性便秘症の健康関連QOLや労働生産性に与える影響－傾向スコア解析による検討－2020
- Author(s)
  富田寿彦，馬場健次，数森清康，大島忠之，福井広一，三輪洋人．
- Organizer
  第21回日本神経消化器病学会・第47回日本潰瘍学会
- Data Source
  KAKENHI-PROJECT-18K07986
[Presentation] Relationship between bile acids and low-grade inflammation of small intestine in IBS2019
- Author(s)
  Horikawa T, Oshima T, Li M, Kondo T, Kono T, Tozawa K, Tomita T, Fukui H, Watari J, Miwa H
- Organizer
  The 12th International Gastrointestinal Consensus Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09297
[Presentation] Alteration of colonic mucosal permeability under antibiotics-induced dysbiotic condition2019
- Author(s)
  Ran Y, Fukui H, Xu X, Kondo T, Kono T, Tozawa K, Tomita T, Oshima T, Watari J, Miwa H.
- Organizer
  Annual Meetings of the American Gastroenterology Association and American Association for the Study of Liver Disease at the Digestive Disease Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Presentation] Antibiotics treatment affects body metabolism and GI motility accompanied by the alteration of macrophage polarization in the colonic tissues2019
- Author(s)
  Fukui H, Inoue Y, Ran Y, Kondo T, Kono T, Tozawa K, Tomita T, Oshima T, Watari J, Miwa H.
- Organizer
  nnual Meetings of the American Gastroenterology Association and American Association for the Study of Liver Disease at the Digestive Disease Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Presentation] Axis of Reg III/STAT3-associated cytokines in DSS-induced colitis in mice2019
- Author(s)
  Fukui H, Nishimura H, Ogawa T, Kondo T, Kono T, Tozawa K, Tomita T, Oshima T, Miwa H.
- Organizer
  Asian Pacific Digestive Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Presentation] Alteration of gut microbiota affects Reg IIIγ expression in the intestine2019
- Author(s)
  Nishimura H, Fukui H, Ogawa T, Kondo T, Kono T, Tozawa K, Tomita T, Oshima T, Miwa H.
- Organizer
  Asian Pacific Digestive Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Presentation] 機能性ディスペプシアにおける十二指腸微細炎症（Duodenal microinflammation in functional dyspepsia）2019
- Author(s)
  大島忠之，滝　正登，清　裕生，堀川知紀，Li Min，西井謙夫，富田寿彦，福井広一，渡　二郎，三輪洋人
- Organizer
  第15回日本消化管学会総会学術集会
- Data Source
  KAKENHI-PROJECT-16K09297
[Presentation] Antibiotics treatment prolongs gastrointestinal transit time accompanied by increase of colonic GLP-1/GPR43 expression.2018
- Author(s)
  Inoue Y, Fukui H, Xu X, Kondo T, Kono T, Tozawa K, Ohda Y, Tomita T, Oshima T, Watari J, Miwa H.
- Organizer
  Annual Meetings of the American Gastroenterology Association and American Association for the Study of Liver Disease at the Digestive Disease Week.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Presentation] 母子分離ラットモデルにおける腸内細菌叢と消化管機能に関する検討2018
- Author(s)
  福井広一，大島忠之，三輪洋人.
- Organizer
  第104回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-17K09363
[Presentation] CDCA released proinflammatory cytokine from small intestinal epithelial cells2018
- Author(s)
  Horikawa T, Oshima T, Li M, Kondo T, Kono T, Tozawa K, Tomita T, Fukui H, Watari J, Miwa H
- Organizer
  3rd Meeting of the Federation of Neurogastroeterology and Motility Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09297
[Presentation] Clinical outcome of patients after endoscopic resection for T1-stage colorectal cancer.2018
- Author(s)
  Eda H, Fukui H, Kono T, Kitayama Y, Nakamura K, Tamura A, Ogawa T, Yamasaki T, Kondo T, Tozawa K, Tomita T, Oshima T, Watari J, Miwa H.
- Organizer
  Asian Pacific Digestive Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Presentation] Capsule endoscopic observation of small intestine in patients with familial adenomatous polyposis.2018
- Author(s)
  Kono T, Fukui H, Katsuyuki T, Tomita T, Oshima T, Watari J, Miwa H.
- Organizer
  Asian Pacific Digestive Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Presentation] Microbiota and gut hormones2017
- Author(s)
  Fukui H, Miwa H.
- Organizer
  5th Biennial Congress of the Asian Neurogastroenterology & Motility Association
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Presentation] Duodenal low-grade inflammation and tight junction proteins in functional dyspepsia.2017
- Author(s)
  Taki M, Oshima T, Takimoto M, Nakamura K, Tamura A, Hara K, Kobayashi M, Okugawa T, Kono T, Tozawa K, Tomita T, Taniguchi Y, Ohda Y, Fukui H, Watari J, Miwa H.
- Organizer
  Digestive Disease Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09297
[Presentation] Effect of gut microbiota on Reg IIIr expression in relation to intestinal immunity.2017
- Author(s)
  Xin Xu, Fukui H, Eda H, Yamasaki T, Kondo T, Tozawa K, Ohda Y, Tomita T, Oshima T, Watari J, Miwa H.
- Organizer
  5th Biennial Congress of Asian Neurogastroenterology and Motility Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Presentation] Effect of gut microbiota on GLP-1 receptor expression in relation to gastrointestinal motility.2017
- Author(s)
  Xin Xu, Fukui H, Eda H, Yamasaki T, Kondo T, Tozawa K, Ohda Y, Tomita T, Oshima T, Watari J, Miwa H.
- Organizer
  Annual Meetings of the American Gastroenterology Association and American Association for the Study of Liver Disease at the Digestive Disease Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Presentation] Role of gut microbiota on GLP-1 receptor expression and gastrointestinal motility.2017
- Author(s)
  Xin Xu, Fukui H, Eda H, Yamasaki T, Kondo T, Tozawa K, Ohda Y, Tomita T, Oshima T, Watari J, Miwa H.
- Organizer
  5th Biennial Congress of Asian Neurogastroenterology and Motility Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Presentation] Low-grade inflammation and epithelial junctional proteins of duodenal mucosa in functional dyspepsia2017
- Author(s)
  Masato Taki, Tadayuki Oshima, Kumiko Nakamura, Mayu Takimoto, Akio Tamura, Ken Hara, Masaya Kobayashi, Takuya Okugawa, Tomoaki Kono, Katsuyuki Tozawa, ToshihikoTomita, Yoshio Ohda, Hirokazu Fukui, Jiro Watari, Hiroto Miwa
- Organizer
  ANMA & JSNM Joint Meeting 2017
- Place of Presentation
  Osaka International Convention Center (大阪府大阪市)
- Year and Date
  2017-03-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09297
[Presentation] Relationship between intestinal motility and small intestinal inflammation after acute colitis.2017
- Author(s)
  Fukui H, Kodani M, Tozawa K, Ohda Y, Tomita T, Oshima T, Watari J, Miwa H.
- Organizer
  Annual Meetings of the American Gastroenterology Association and American Association for the Study of Liver Disease at the Digestive Disease Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Presentation] Effect of gut microbiota on Reg IIIr expression in relation to intestinal immunity2017
- Author(s)
  Xin Xu, Fukui H, Eda H, Yamasaki T, Kondo T, Tozawa K, Ohda Y, Tomita T, Oshima T, Watari J, Miwa H
- Organizer
  Biennial Congress of Asian Neurogastroenterology and Motility Association
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2017-03-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460953
[Presentation] 腸内細菌が GLP-1/GLP-1 receptor 発現と消化管運動に及ぼす影響について2017
- Author(s)
  福井広一，江田裕嗣，三輪洋人．
- Organizer
  第 103 回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-17K09363
[Presentation] The duodenum, a new target for research2017
- Author(s)
  Tadayuki Oshima, Masato Taki, Liping Wu, Toshihiko Tomita, Hirokazu Fukui, Jiro Watari, Hiroto Miwa
- Organizer
  ANMA & JSNM Joint Meeting 2017
- Place of Presentation
  Osaka International Convention Center (大阪府大阪市)
- Year and Date
  2017-03-23
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09297
[Presentation] Ratio of neutrophil to lymphocytes is useful to predict the prognosis of patients with paclitaxel plus ramucirumab treatment for unresectable advanced gastric cancer.2017
- Author(s)
  Hara K, Fukui H, Tozawa K, Takimoto M, Nakamura K, Tamura A, Okugawa T, Tomita T, Ohda Y, Oshima T, Watari J, Miwa H.
- Organizer
  Annual Meetings of the American Gastroenterology Association and American Association for the Study of Liver Disease at the Digestive Disease Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09363
[Presentation] Role of microbiota in gut hormone and gastrointestinal motility2017
- Author(s)
  Fukui H
- Organizer
  2017 Academic Congress of Intestinal Diseases Tianjin&・China
- Place of Presentation
  Tianjin, China
- Year and Date
  2017-01-08
- Invited
- Data Source
  KAKENHI-PROJECT-26460953
[Presentation] Role of microbiota in gut hormone and gastrointestinal motility2017
- Author(s)
  Fukui H
- Organizer
  2017 Academic Congress of Intestinal Diseases Tianjin・China
- Invited
- Data Source
  KAKENHI-PROJECT-17K09363
[Presentation] Involvement of gut microbiota in the association between macrophage and gastrointestinal motility2016
- Author(s)
  Yang M, Fukui H, Eda H, Kodani M, Yamasaki T, Kondo T, Ikehara H, Ohda Y, Tomita T, Oshima T, Watari J, Miwa H
- Organizer
  Annual Meetings of the American Gastroenterology Association and American Association for the Study of Liver Disease at the Digestive Disease Week
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-05-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460953
[Presentation] Effect of REG protein on the link between claudin expression and mucosal permeability in the small intestine2016
- Author(s)
  Fukui H, Kitayama Y, Hara K, Yamasaki T, Kondo T, Ikehara H, Ohda Y, Tomita T, Oshima T, Watari J, Miwa H
- Organizer
  Annual Meetings of the American Gastroenterology Association and American Association for the Study of Liver Disease at the Digestive Disease Week
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-05-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460953
[Presentation] Alteration of gastrointestinal motility and mast cell behavior in mice after DSS-induced colitis2016
- Author(s)
  Kodani M, Fukui H, Tomita T, Oshima T, Watari J, Miwa H.
- Organizer
  Federation of Neurogastroenterology and Motility Meeting 2016
- Place of Presentation
  San Francisco, USA
- Year and Date
  2016-08-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460953
[Presentation] Serum Reg Ia is a marker to predict histological and clinical activity in ulcerative colitis2015
- Author(s)
  Tozawa K, Fukui H, Yamasaki T, Kondo T, Kono T, Toyoshima F, Ikehara H, Ohda Y, Tomita T, Oshima T, Watari J, Miwa H
- Organizer
  Annual Meetings of the American Gastroenterology Association and American Association for the Study of Liver Disease at the Digestive Disease Week
- Place of Presentation
  Washington, USA
- Year and Date
  2015-05-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460953
[Presentation] Effect of REG protein on mucosal permeability and adhesion molecule expression in the small intestine2015
- Author(s)
  Kitayama Y, Fukui H, Yamasaki T, Kondo T, Kono T, Toyoshima F, Ikehara H, Ohda Y, Tomita T, Oshima T, Watari J, Miwa H
- Organizer
  Annual Meetings of the American Gastroenterology Association and American Association for the Study of Liver Disease at the Digestive Disease Week
- Place of Presentation
  Washington, USA
- Year and Date
  2015-05-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460953
[Presentation] Upregulation and the regulation of esophageal epithelial-derived IL-33 in non-erosive reflux disease2015
- Author(s)
  Hiroo Sei, Tadayuki Oshima, Jing Shan, Liping Wu, Takashi Kondo, Tomoaki Kono, Fumihiko Toyoshima, Katsuyuki Tozawa, Hisatomo Ikehara, Yoshio Ohda, Toshihiko Tomita, Hirokazu Fukui, Jiro Watari, Hiroto Miwa
- Organizer
  Digestive Disease Week 2015
- Place of Presentation
  Walter E. Washington Convention Center, Washington, DC
- Year and Date
  2015-05-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460939
[Presentation] 食道上皮細胞内のIL-33は胃食道逆流症の増悪に関与する2015
- Author(s)
  大島忠之，単　晶，ウ　リピン，清　裕生，原　謙，小川智広，山崎尊久，奥川卓也，河野友彰，近藤　隆，池原久朝，上山茂充，谷口友佳子，富田寿彦，應田義雄，福井広一，渡　二郎，三輪洋人
- Organizer
  合同学術集会2015 第17回日本神経消化器病学会
- Place of Presentation
  沖縄科学技術大学院大学，沖縄
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-25460939
[Presentation] 非びらん性食道胃逆流症におけるIL-33の発現と炎症性サイトカインの産生に関する検討2015
- Author(s)
  清　裕生，大島忠之，L. Wu，山崎尊久，近藤　隆，河野友彰，豊島史彦，戸澤勝之，池原久朝，富田寿彦，應田義雄，福井広一，渡　二郎，三輪洋人
- Organizer
  第57回日本消化器病学会大会（JDDW 2015）
- Place of Presentation
  グランドプリンス新高輪，東京
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25460939
[Presentation] 機能性ディスペプシアにおける十二指腸粘膜の炎症細胞浸潤2015
- Author(s)
  清　裕生，大島忠之，ウ　リピン，原　謙，小川智広，山崎尊久，奥川卓也，近藤　隆，河野友彰，戸澤勝之，池原久朝，谷口友佳子，上山茂充，富田寿彦，應田義雄，福井広一，渡　二郎，三輪洋人
- Organizer
  合同学術集会2015 第17回日本神経消化器病学会
- Place of Presentation
  沖縄科学技術大学院大学，沖縄
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-25460939
[Presentation] Effect of H. pylori infection on GLP-1 expression and gastrointestinal motility2015
- Author(s)
  Eda H, Fukui H, Kitayama Y, Hara K, Yamasaki T, Kondo T, Tozawa K, Ikehara H, Ohda Y, Tomita T, Oshima T, Watari J, Miwa H
- Organizer
  Asia Pacific Digestive Week
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460953
[Presentation] 胃炎―胃癌相関におけるSTAT3シグナル活性の意義について2014
- Author(s)
  福井広一
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2014-04-24
- Data Source
  KAKENHI-PROJECT-23590929
[Presentation] NSAID 起因性消化管粘膜傷害における Reg 蛋白の役割2014
- Author(s)
  福井広一，原謙，三輪洋人
- Organizer
  第 56 回日本消化器病学会大会
- Place of Presentation
  神戸
- Year and Date
  2014-10-23
- Data Source
  KAKENHI-PROJECT-26460953
[Presentation] Involvement of STAT3 activation in the development of early gastric cancer2014
- Author(s)
  Sakamoto H, Fukui H, Kono T, Ikehara H, Tomita T, Oshima T, Watari J, Miwa H
- Organizer
  Asia Pacific Digestive Week
- Place of Presentation
  Bali, Indonesia
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-26460953
[Presentation] 胃炎－胃癌相関における STAT3 シグナル活性の意義について2014
- Author(s)
  福井広一，渡二郎，三輪洋人
- Organizer
  第 100 回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2014-04-24
- Data Source
  KAKENHI-PROJECT-26460953
[Presentation] NSAID起因性消化管粘膜傷害におけるReg遺伝子の発現意義について2013
- Author(s)
  福井広一
- Organizer
  第41回日本潰瘍学会
- Place of Presentation
  吹田市
- Year and Date
  2013-12-07
- Data Source
  KAKENHI-PROJECT-23590929
[Presentation] GROαpromotes invasion of gastric cancer cells2013
- Author(s)
  Fukui H
- Organizer
  Digestive Disease Week 2013
- Place of Presentation
  Orland, USA
- Year and Date
  2013-05-18
- Data Source
  KAKENHI-PROJECT-23590929
[Presentation] Expression of Reg family genes in the gastrointestinal tract injured by indomethacin2013
- Author(s)
  Sun C, Fukui H
- Organizer
  The Asian Pacific Digestive Week/World Congress of Gastroenterology
- Place of Presentation
  Shanghai, China
- Year and Date
  2013-09-23
- Data Source
  KAKENHI-PROJECT-23590929
[Presentation] 胃癌細胞の浸潤におけるインターロイキン22の役割について2012
- Author(s)
  福井広一
- Organizer
  第98回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2012-04-20
- Data Source
  KAKENHI-PROJECT-23590929
[Presentation] 腸上皮化生と胃癌組織におけるREG蛋白発現の意義について2012
- Author(s)
  福井広一
- Organizer
  第54回日本消化器病学会大会
- Place of Presentation
  神戸
- Year and Date
  2012-10-11
- Data Source
  KAKENHI-PROJECT-23590929
[Presentation] REG Iαplays a role in resistance to chemotherapy in gastric cancer2012
- Author(s)
  Fukui H
- Organizer
  United European Gastroenterology Week
- Place of Presentation
  Amsterdam, Netherland
- Year and Date
  2012-10-23
- Data Source
  KAKENHI-PROJECT-23590929
[Presentation] Involvement of IL-22 signaling in gastric cancer cell invasion2012
- Author(s)
  Fukui H
- Organizer
  Digestive Disease Week 2012
- Place of Presentation
  San Diego, USA
- Year and Date
  2012-05-20
- Data Source
  KAKENHI-PROJECT-23590929
[Presentation] 胃炎発癌における STAT3/REG シグナルの役割2011
- Author(s)
  福井広一
- Organizer
  第 53 回日本消化器病学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590929
[Presentation] 胃癌治療における REG 蛋白の標的分子としての可能性について2011
- Author(s)
  福井広一
- Organizer
  第 97 回日本消化器病学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590929
[Presentation] Involvement of IL-22/STAT3 signaling in the expression of antimicrobial molecules in gastrointestinal epithelial cells2011
- Author(s)
  Fukui H
- Organizer
  Digestive Disease Week 2011
- Place of Presentation
  Chicago, USA
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-23590929
[Presentation] Involvement of IL-22/STAT3 Signaling in the Expression of Antimicrobial Molecules in Gastrointestinal Epithelial Cells2011
- Author(s)
  Fukui H
- Organizer
  Digestive Disease Week 2011
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-23590929
[Presentation] 胃炎発癌におけるSTAT3/REGシグナルの役割2011
- Author(s)
  福井広一
- Organizer
  第53回日本消化器病学会大会
- Place of Presentation
  福岡
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-23590929
[Presentation] 胃癌治療におけるREG蛋白の標的分子としての可能性について2011
- Author(s)
  福井広一
- Organizer
  第97回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-23590929
[Presentation] 潰瘍性大腸炎関連腫瘍におけるREG Iα発現の意義2010
- Author(s)
  福井広一
- Organizer
  第99回日本病理学会総会
- Place of Presentation
  東京
- Year and Date
  2010-04-27
- Data Source
  KAKENHI-PROJECT-20590747
[Presentation] 潰瘍性大腸炎関連腫瘍におけるREG I発現の意義2010
- Author(s)
  福井広一
- Organizer
  第99回日本病理学会総会
- Place of Presentation
  東京
- Year and Date
  2010-04-27
- Data Source
  KAKENHI-PROJECT-20590747
[Presentation] 潰瘍性大腸炎粘膜におけるインターロイキン22おまびREG Iαの発現について2009
- Author(s)
  福井広一
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20590747
[Presentation] 潰瘍性大腸炎粘膜におけるインターロイキン22およびREG Iαの発現について2009
- Author(s)
  福井広一
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20590747
[Presentation] 大腸粘液癌におけるヘパラン硫酸発現とEXTL3プロモーターメチレーションの関連について2009
- Author(s)
  福井広一
- Organizer
  Japan DDW 2009 第51回日本消化器病学会大会
- Place of Presentation
  京都
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-20590747
[Presentation] EXTL3 promoter methylation is involved in the reduction of heparan sulfate expression in mucinous colorectal cancers2008
- Author(s)
  福井広一
- Organizer
  日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20590747
[Presentation] REG Iα gene expression is inducible by IL-6-STAT3 signal pathway in H. pylori-induced gastritis2008
- Author(s)
  Fukui H
- Organizer
  7th China-Korea-Japan Joint Conference on Helicobacter Infection
- Place of Presentation
  Kyoto
- Year and Date
  2008-02-22
- Data Source
  KAKENHI-PROJECT-20590747
[Presentation] GROa promotes invasion of gastric cancer cells
- Author(s)
  Fukui H
- Organizer
  Digestive Disease Week 2013
- Place of Presentation
  Orland, USA
- Data Source
  KAKENHI-PROJECT-23590929
[Presentation] REG Ia plays a role in resistance to chemotherapy in gastric cancer
- Author(s)
  Fukui H
- Organizer
  United European Gastroenterology Week
- Place of Presentation
  Amsterdam, Netherland
- Data Source
  KAKENHI-PROJECT-23590929
[Presentation] Expression of Reg family genes in the gastrointestinal tract injured by indomethacin
- Author(s)
  Sun C, Fukui H, Shan Jin, Toshihiko Tomita, Tadayuki Oahima, Jiro Watari, Miwa H.
- Organizer
  The Asian Pacific Digestive Week/World Congress of Gastroenterology
- Place of Presentation
  Shanghai, China
- Data Source
  KAKENHI-PROJECT-23590929
[Presentation] 胃炎―胃癌相関におけるSTAT3シグナル活性の意義につい
- Author(s)
  福井広一
- Organizer
  第 100 回日本消化器病学会総会
- Place of Presentation
  東京都千代田区
- Data Source
  KAKENHI-PROJECT-23590929
[Presentation] NSAID 起因性消化管粘膜傷害における Reg 遺伝子の発現意義について
- Author(s)
  福井広一
- Organizer
  第 41 回日本潰瘍学会
- Place of Presentation
  吹田市
- Data Source
  KAKENHI-PROJECT-23590929
[Presentation] 胃癌細胞の浸潤におけるインターロイキン 22 の役割について
- Author(s)
  福井広一
- Organizer
  第98回日本消化器病学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590929
[Presentation] 腸上皮化生と胃癌組織における REG 蛋白発現の意義について
- Author(s)
  福井広一
- Organizer
  第54回日本消化器病学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23590929

1. MIWA Hiroto (80190833)

# of Collaborated Projects: 8 results

# of Collaborated Products: 109 results
2. OSHIMA Tadayuki (00381814)

# of Collaborated Projects: 6 results

# of Collaborated Products: 78 results
3. WATARI Jiro (10311531)

# of Collaborated Projects: 4 results

# of Collaborated Products: 66 results
4. TOMITA TOSHIHIKO (60388824)

# of Collaborated Projects: 3 results

# of Collaborated Products: 27 results
5. 新崎信一郎 (60546860)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. Ohmuraya Masaki (60398229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 横山陽子 (40529004)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. IMURA Johji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. YASUDA Koubun

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 藤盛孝博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 戴毅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 神田浩里

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fukui Hirokazu 福井 広一

FUKUI Hirokazu 福井 広一

Research Projects

Research Products

Co-Researchers

Role of Reg family proteins in the gastrointestinal environment and mucosal barrier functionPrincipal Investigator

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Oligosaccharide-mediated regulation of intestinal inflammation by LRG, a novel serum biomarker for inflammatory bowel disease

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Role of Reg family proteins in the link between dysbiosis and minimal inflammation in the gastrointestinal tractPrincipal Investigator

Principal Investigator

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The role of Reg family in pancreatitis

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Development of new therapy for eosinophilic gastrointestinal diseases targeting the regulation of mucosal barrier

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Alterations of gut microbiome and mucosal permeability in inactive IBD patients with IBS-like symptom

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Review Section

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Role of Reg protein on the mucosal barrier function in the inflammatory gastrointestinal diseasesPrincipal Investigator

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The development and application of in vivo evaluation of mucosal barrier function in functional gastrointestinal disorders

Principal Investigator

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Role of Reg protein on the maintenance of mucosal homeostasis in the gastrointestinal tractPrincipal Investigator

Principal Investigator

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Duodenal epithelial intercellular junction and IL-33 on the development of dyspepsia

Principal Investigator

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Protective role of Reg protein on mucosal injury in the gastrointestinal tractPrincipal Investigator

Principal Investigator

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Role of REG protein in the regeneration and carcinogenesis of colorectal epithelial cellsPrincipal Investigator

Principal Investigator

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Roles of Reg protein in the pathophysiology of ulcerative colitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Fukui Hirokazu 福井広一

FUKUI Hirokazu 福井広一