SHIRAKAWA Yasuhiro 白川靖博

Researcher Number	60379774
Affiliation (based on the past Project Information) *help	2020 – 2023: 岡山大学, 医学部, 客員研究員 2016 – 2019: 岡山大学, 医歯薬学総合研究科, 准教授 2015: 岡山大学, 大学院医歯薬学総合研究科消化器外科, 准教授 2014 – 2015: 岡山大学, 医歯(薬)学総合研究科, 准教授 2014 – 2015: 岡山大学, 大学院医歯薬学総合研究科, 准教授 2013: 岡山大学, 大学病院, 講師 2004 – 2005: 岡山大学, 医学部・歯学部附属病院, 医員
Review Section/Research Field	Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related Except Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related / Basic Section 58060:Clinical nursing-related
Keywords	Principal Investigator 食道癌 / 癌関連線維芽細胞 / がん微小環境 / 治療抵抗癌 / 放射線治療 / 放射線療法 / 化学療法 / 癌微小環境 / 転移 / 遠隔転移 … More / 腫瘍微小環境 / 癌関連線維芽細胞尾 / 遊走能 / 浸潤能 / リンパ節転移 / 近赤外線光 / 光線免疫療法 / 新規治療法 / 新規治療薬 / 食道がん / がん関連線維芽細胞 … More Except Principal Investigator 食道癌 / 癌関連線維芽細胞 / CAFs / 光線免疫療法 / がん微小環境 / Photoimmunotherapy / 癌微小環境 / PD-L1 / 標的治療 / HER2 / EGFR / PDXモデル / FAP / immunotherapy / Esophageal cancer / Tumor microenvironment / mixmethod research / QOL調査 / 半構造化面接 / 胸部食道がん / 長期がんサバイバー / 内容分析 / 食道がん術後長期サバイバー / 食道切除術 / 日常生活支援 / 術後長期サバイバー / 尺度開発 / 長期サバイバー / 食道がん / 放射線療法 / 化学療法 / 近赤外線光 / 線維芽細胞 / 消化器癌 / 治療抵抗性 / CAF / Canada / international information exchange / animal model of diabetes / insulin-secreting immortalized human cells / human telomerase gene / lentiviral vector / ブタ糖尿病モデル / カナダ / 国際情報交換 / 糖尿病動物モデル / インスリン分泌ヒト不死化株 / ヒトテロメラーゼ遺伝子 / レンチウイルスベクター / PCR / 遺伝子解析 / GFP / TGF-beta / アデノウイルス / テロメラーゼ / 上皮間葉転換 / 循環癌細胞 / ﾄﾗﾝｽﾚｰｼｮﾅﾙﾘｻｰﾁ / トランスレーショナルリサーチ / 医療・福祉 / 細胞・組織 / 遺伝子 / 癌 Less

Exploratory study on the relationship between CAFs and the PD1/PD-L1
- Principal Investigator
  
  Tanabe Shunsuke
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Okayama University
Preclinical study of photoimmunotherapy for tumor microenvironment
- Principal Investigator
  
  Noma Kazuhiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Okayama University
Negative spiral mechanism of cancer associated microenvironment iPrincipal Investigator
- Principal Investigator
  
  Shirakawa Yasuhiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Okayama University
The construction of daily life support nursing model to postoperative long-term survivor of thoracic esophagus cancer
- Principal Investigator
  
  Mori Keiko
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58060:Clinical nursing-related
- Research Institution
  Okayama University
  Hamamatsu University School of Medicine
Inspection about the influence of circulating tumor microenvironment for metastasisPrincipal Investigator
- Principal Investigator
  
  Shirakawa YAsuhiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Okayama University
Novel targeting therapy to cancer-associated fibroblasts for treatment-resistant carcinomas
- Principal Investigator
  
  Noma Kazuhiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Okayama University
"Cell-in-cell" activity-based tumor-specific delivery of biologics
- Principal Investigator
  
  FUJIWARA Toshiyoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Okayama University
Therapeutic potential of circulating tumor microenvironment based on metastatic mechanismPrincipal Investigator
- Principal Investigator
  
  Shirakawa Yasuhiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Okayama University
Fluorescent virus-guided capturing of epithelial-mesenchymal transition (EMT)-induced circulating tumor cells (CTCs) for genetic analysis
- Principal Investigator
  
  FUJIWARA Toshiyoshi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Okayama University
Development of cell therapies using reversibly immortalized human pancreatic beta cell lines
- Principal Investigator
  
  KOBAYASHI Naoya
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Okayama University

All 2019 2017 2015 2005

All Journal Article Presentation

[Journal Article] Cancer-associated fibroblasts (CAFs) promote the lymph node metastasis of esophageal squamous cell carcinoma.2019
- Author(s)
  Kashima H, Noma K, Ohara T, Kato T, Katsura Y, Komoto S, Sato H, Katsube R, Ninomiya T, Tazawa H, Shirakawa Y, Fujiwara T.
- Journal Title
  
  International Journal of Cancer
  
  Volume: 144 Issue: 4 Pages: 828-840
- DOI
  10.1002/ijc.31953
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05416, KAKENHI-PROJECT-16K10500
[Journal Article] 宿主正常細胞である癌関連線維芽細胞を標的とした新たな食道癌治療法の開発2015
- Author(s)
  野間和広, 賀島　肇, 二宮卓之, 勝部亮一, 渡邉伸一郎, 大原利章, 田澤　大, 香川俊輔, 白川靖博, 藤原俊義
- Journal Title
  
  癌と化学療法
  
  Volume: 42 Pages: 1228-1230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462020
[Journal Article] Therapeutic Potential of Targeting Cancer-Associated Fibroblasts in Esophageal Cancer2015
- Author(s)
  Noma K, Kashima H, Ninomiya T, Katsube R, Watanabe S, Ohara T, Tazawa H, Kagawa S, Shirakawa Y, Fujiwara T.
- Journal Title
  
  癌と化学療法
  
  Volume: 42 Pages: 1228-30
- Data Source
  KAKENHI-PROJECT-26861077
[Journal Article] Establishment of insulin-secreting human cell lines for diabetes-targeted cell therapies.2005
- Author(s)
  Kobayashi N, Okitsu T, Chen Y, Yamatsuji T, Shirakawa Y, Inai K, Akasu H, Tanaka N
- Journal Title
  
  Transplantation Now 18(4)
  
  Pages: 429-434
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390380
[Presentation] 癌関連線維芽細胞は食道癌のリンパ節転移を促進するか　～臨床検体の解析と同所移植モデルを用いた検証～2017
- Author(s)
  賀島　肇，野間　和広，佐藤　浩明，桂　佑貴，加藤　卓也，大原　利章，田澤　大，白川　靖博，藤原　俊義
- Organizer
  第 26 回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-16K10500
[Presentation] Cancer associated fibroblasts promote tumor metastasis coexisting with cancer cells in blood circulation2017
- Author(s)
  Kashima H, Noma K, Sato H, Katsura Y, Kato T, Ohara T, Tazawa H, Shirakawa Y, Fujiwara T
- Organizer
  AACR annual meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10500
[Presentation] 食道癌におけるFAP(fibroblast activation protein)陽性癌関連線維芽細胞の発現と癌転移の関係2015
- Author(s)
  賀島肇，野間和広，加藤卓也，勝部亮一，二宮卓之，大原利章，田澤大，白川靖博，香川俊輔，藤原俊義
- Organizer
  第26回消化器癌発生学会
- Place of Presentation
  鳥取県　米子市
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-25462020

1. NOMA Kazuhiro (10534761)

# of Collaborated Projects: 6 results

# of Collaborated Products: 5 results
2. FUJIWARA Toshiyoshi (00304303)

# of Collaborated Projects: 5 results

# of Collaborated Products: 4 results
3. KAGAWA Shunsuke (00362971)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. KASHIMA Hajime

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. KOBAYASHI Naoya (10325102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. IWAGAKI Hiromi (50240867)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MOCHITATE Katsumi (20132863)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MATSUKAWA Hiroyoshi (10379729)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OHARA Toshiaki (40623533)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. TAZAWA Hiroshi (90415513)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. Mori Keiko (70325091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Tanabe Shunsuke (20534770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 雄西智恵美 (00134354)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 竹内裕也 (20265838)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 本家淳子 (20824981)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 秋元典子 (90290478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 片山はるみ (90412345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 末田朋美 (90553983)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 前田直見 (10751117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. KATSUBE Ryoichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. 中路修平

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHIRAKAWA Yasuhiro 白川 靖博

Research Projects

Research Products

Co-Researchers

Exploratory study on the relationship between CAFs and the PD1/PD-L1

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Preclinical study of photoimmunotherapy for tumor microenvironment

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Negative spiral mechanism of cancer associated microenvironment iPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The construction of daily life support nursing model to postoperative long-term survivor of thoracic esophagus cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Inspection about the influence of circulating tumor microenvironment for metastasisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel targeting therapy to cancer-associated fibroblasts for treatment-resistant carcinomas

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

"Cell-in-cell" activity-based tumor-specific delivery of biologics

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Therapeutic potential of circulating tumor microenvironment based on metastatic mechanismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Fluorescent virus-guided capturing of epithelial-mesenchymal transition (EMT)-induced circulating tumor cells (CTCs) for genetic analysis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of cell therapies using reversibly immortalized human pancreatic beta cell lines

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cancer-associated fibroblasts (CAFs) promote the lymph node metastasis of esophageal squamous cell carcinoma.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 宿主正常細胞である癌関連線維芽細胞を標的とした新たな食道癌治療法の開発2015

Author(s)

Journal Title

Data Source

[Journal Article] Therapeutic Potential of Targeting Cancer-Associated Fibroblasts in Esophageal Cancer2015

Author(s)

Journal Title

Data Source

[Journal Article] Establishment of insulin-secreting human cell lines for diabetes-targeted cell therapies.2005

Author(s)

Journal Title

SHIRAKAWA Yasuhiro 白川靖博

[Presentation] 癌関連線維芽細胞は食道癌のリンパ節転移を促進するか　～臨床検体の解析と同所移植モデルを用いた検証～2017