Shimoyamada Hiroaki 下山田博明

… Alternative Names

SHIMOYAMADA Hiroaki 下山田博明

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Researcher Number	60381472
Other IDs
Affiliation (Current)	2025: 獨協医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2014: 杏林大学, 医学部, 講師 2011 – 2013: 杏林大学, 医学部, 助教 2008 – 2010: 横浜市立大学, 医学部, 助教 2007: 横浜市立大学, 医学研究科, 助教 2005 – 2006: 横浜市立大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Experimental pathology / Human pathology Except Principal Investigator Human pathology
Keywords	Principal Investigator 血管内皮増殖因子 / 肺癌 / 悪性中皮腫 / 悪件中皮腫 / NAB2 / 中皮腫 / VEGF / Egr-1 / 癌性リンパ管症 / 胸膜播種 … More Except Principal Investigator … More 肺癌 / 小細胞癌 / 分子病理学 / 人体病理学 / POU / 転写因子 / 分化形質 / カルチノイド腫瘍 / 大細胞神経内分泌癌 / 小細胞肺癌 / 神経内分泌癌 / CLIC4 / 異型性 / lung cancer / atypism / 悪性神経内分泌腫瘍 / TTF-1 / 悪性神経内分泌細胞 / 肺がん / エピジェネティック / エピジェネティックス / メチレーション / VEGF-A / プロモーター / エピジェネティクス / 癌化 / 癌抑制遺伝子 / 癌遺伝子 / Egr-1 / インスリン様増殖因子結合蛋白2 / 大細胞癌 / 扁平上皮癌 / 腺癌 / NeuroD1 / Promoter / IGFBP-2 Less

Molecular pathological analyses of proneural/neuroendocrine phenotype-obtaining mechanisms on lung cancer cells
- Principal Investigator
  
  YAZAWA Takuya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Chiba University
  Kyorin University
The molecular basis of morphological atypism (proteome analysis of KRAS downstream factors)
- Principal Investigator
  
  OKUDELA KOJI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Yokohama City University
Therapeutic approach to lung cancer and malignant mesothelioma by inhibition of VEGR-VEGFR pathwayPrincipal Investigator
- Principal Investigator
  
  SHIMOYAMADA Hiroaki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kyorin University
  Yokohama City University
Analysis of expression mechanisms of neuroendocrine cancer cell-specific molecules via TTF-1
- Principal Investigator
  
  YAZAWA Takuya
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kyorin University
  Yokohama City University
Exhaustive search for onco-suppressor genes induced by Egr-1 and cause-analysis of their repression in association with carcinogenesis
- Principal Investigator
  
  YAZAWA Takuya
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Yokohama City University
肺小細胞癌において高発現するインスリン様増殖因子結合蛋白2の発現機序及び機能解析
- Principal Investigator
  
  KITAMURA Hitoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Yokohama City University
肺癌の胸幹播種・癌性リンパ管症における血管内皮増殖因子の関与とその治療法の解明Principal Investigator
- Principal Investigator
  
  下山田博明
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Yokohama City University

All 2014 2013 2012 2011 2010 2009 2006

All Journal Article Presentation Book

[Book] 臨床画像No.92012
- Author(s)
  下山田博明
- Publisher
  メジカルビュー社
- Data Source
  KAKENHI-PROJECT-22590366
[Journal Article] Expression of developing neural transcription factors in lung carcinoid tumors2014
- Author(s)
  Endo T, Yazawa T, Shishido-Hara Y, FUjiwara M, Shimoyamada H, Ishii J, Sato H, Tachibana K, Takei H, Kondo H, Goya T, Endo S, Kamma H
- Journal Title
  
  Pathology International
  
  Volume: 64 Issue: 8 Pages: 365-374
- DOI
  10.1111/pin.12183
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590428
[Journal Article] POU domain transcription factor BRN2 is crucial for expression of ASCL1, ND1 and neuroendocrine marker molecules and cell growth in small cell lung cancer2013
- Author(s)
  Ishii J, Sato H, Sakaeda M, Shishido-Hara Y, Hiramatsu C, Kamma H, Shimoyamada H, Fujiwara M, Endo T, Aoki I, Yazawa T.
- Journal Title
  
  Pathol Int.
  
  Volume: 63(3) Pages: 158-68
- Data Source
  KAKENHI-PROJECT-22590366
[Journal Article] POU domain transcription factor BRN2 is crucial for expression of ASCL1, ND1 and neuroendocrine marker molecules and cell growth in small cell lung cancer2013
- Author(s)
  Ishii J, Sato H, et al.
- Journal Title
  
  Pathology International
  
  Volume: 63 Issue: 3 Pages: 158-168
- DOI
  10.1111/pin.12042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790361, KAKENHI-PROJECT-24500421, KAKENHI-PROJECT-24590428
[Journal Article] Neural lineage-specific homeoprotein BRN2 is directly involved in TTF1 expression in small-cell lung cancer2013
- Author(s)
  Sakaeda M, Sato H, et al.
- Journal Title
  
  Laboratory Investigation
  
  Volume: 93 Issue: 4 Pages: 408-421
- DOI
  10.1038/labinvest.2013.2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790361, KAKENHI-PROJECT-24500421, KAKENHI-PROJECT-24590428
[Journal Article] Neural lineage-specific homeoprotein BRN2 is directly involved in TTF1 expression in small-cell lung cancer2013
- Author(s)
  Sakaeda M, Sato H, Ishii J, Miyata C, Kamma H, Shishido-Hara Y, Shimoyamada H, Fujiwara M, Endo T, Tanaka R, Kondo H, Goya T, Aoki I, Yazawa T.
- Journal Title
  
  Lab Invest
  
  Volume: 93(4) Pages: 408-21
- Data Source
  KAKENHI-PROJECT-22590366
[Journal Article]2013
- Author(s)
  Sakata R, Shimoyamada H, Yanagisawa M, Murakami T, Makiyama K, Nakaigawa N, Inayama Y, Ohashi K, Nagashima Y, Yao M, Kubota Y
- Journal Title
  
  Nonfunctioning juxtaglomerular cell tumor.
  
  Pages: 973865-973865
- Data Source
  KAKENHI-PROJECT-22590366
[Journal Article] Differences of molecular expression mechanisms among neural cell adhesion molecule 1, synaptophysin, and chrmogranin A in lung cancer cells2012
- Author(s)
  Kashiwagi K, Ishii J, Sakaeda M, Arimasu Y, Shimoyamada H, Sato H, Miyata C, Kamma H, Aoki I, Yazawa T
- Journal Title
  
  Pathol Int
  
  Volume: VOL.62 Issue: 4 Pages: 232-245
- DOI
  10.1111/j.1440-1827.2011.02781.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590376, KAKENHI-PROJECT-22790361, KAKENHI-PROJECT-24590428
[Journal Article] Differences of molecular expression mechanisms among neural cell adehesion molecule 1, synaptophysin, and chromogranin A in lung cancer cells2012
- Author(s)
  Kashiwagi K, Ishii J, Sakaeda M, Arimasu Y, Shimoyamada H, Sato H, Miyata C, Kamma H, Aoki I, Yazawa T.
- Journal Title
  
  Pathol Int
  
  Volume: 62 Pages: 232-245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590376
[Journal Article] Gastric metastasis from a primary renal leiomyosarcoma.2012
- Author(s)
  Yodonawa S, Ogawa I, Yoshida S, Ito H, Kato A, Kubokawa R, Tokoshima E, Shimoyamada H
- Journal Title
  
  Case Rep Gastroenterol
  
  Volume: 6(2) Pages: 314-8
- Data Source
  KAKENHI-PROJECT-22590366
[Journal Article] Differences of molecular expression mechanisms among neural cell adhesion molecule 1, synaptophysin, and chromogranin A in lung cancer cells2012
- Author(s)
  Kashiwagi K, Ishii J, Sakaeda M, Arimasu Y, Shimoyamada H, Sato H, Miyata C, Kamma H, Aoki I, Yazawa T.
- Journal Title
  
  Pathol Int.
  
  Volume: 62(4) Pages: 232-45
- NAID
  10031185195
- Data Source
  KAKENHI-PROJECT-22590366
[Journal Article] Insulin-like growth factor binding protein-4 gene silencing in lung adenocarcinomas2011
- Author(s)
  Sato H, Sakaeda M, Ishii J, Kashiwagi K, Shimoyamada H, Okudela K, Tajiri M, Ohmori T, Ogura T, Woo T, Masuda M, Hirata K, Kitamura H, Yazawa T.
- Journal Title
  
  Pathol Int
  
  Volume: 61 Pages: 19-27
- NAID
  10031185042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590376
[Journal Article] Insulin-like growth factor binding protein-4 gene silencing in lung adenocarcinomas.2011
- Author(s)
  Sato H, Sakaeda M, Ishii J, Kashiwagi K, Shimoyamada H, Okudela K, Tajiri M, Ohmori T, Ogura T, Woo T, Masuda M, Hirata K, Kitamura H, Yazawa T.
- Journal Title
  
  Pathol Int.
  
  Volume: 61(1) Pages: 19-27
- NAID
  10031185042
- Data Source
  KAKENHI-PROJECT-22590366
[Journal Article] Early growth response-1 induces and enhances vascular endothelial growth factor-A expression in lung cancer cells2010
- Author(s)
  Shimoyamada H, Yazawa T, Sato H, Okudela K, Ishii J, Sakaeda M, Kashiwagi K, Suzuki T, Mitsui H, Woo T, Tajiri M, Ohmori T, Ogura T, Masuda M, Oshiro H, Kitamura H.
- Journal Title
  
  Am J Pathol
  
  Volume: 177 Pages: 70-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590376
[Journal Article] Morphometric profiling of lung cancers-its association with clinicopathologic, biologic, and molecular genetic features2010
- Author(s)
  Okudela K, Woo T, Mitsui H, Yazawa T, Shimoyamada H, Tajiri M, Ogawa N, Masuda M, Kitamura H.
- Journal Title
  
  Am J Surg Pathol
  
  Volume: 34(2) Pages: 243-55
- Data Source
  KAKENHI-PROJECT-22590366
[Journal Article] Proposal of an improved histological sub-typing system for lung adenocarcinoma - significant prognostic values for stage I disease.2010
- Author(s)
  Okudela K, Woo T, Mitsui H, Yazawa T, Shimoyamada H, Tajiri M, Ogawa N, Masuda M, Kitamura H.
- Journal Title
  
  Int J Clin Exp Pathol.
  
  Volume: 3(4) Pages: 348-66
- Data Source
  KAKENHI-PROJECT-22590366
[Journal Article] Proposal of an improved histological sub-typing system for lung adenocarcinoma. significant prognostic values for stage I disease2010
- Author(s)
  Okudela K, Woo T, Mitsui H, Yazawa T, Shimoyamada H, Tajiri M, Ogawa N, Masuda M, Kitamura H.
- Journal Title
  
  Int J Clin Exp Pathol
  
  Volume: 25 Pages: 348-366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590376
[Journal Article] Morphometric profiling of lung cancers. its association with clinicopathologic, biologic, and molecular genetic features2010
- Author(s)
  Okudela K, Woo T, Mitsui H, Yazawa T, Shimoyamada H, Tajiri M, Ogawa N, Masuda M, Kitamura H.
- Journal Title
  
  Am J Surg Pathol
  
  Volume: 34 Pages: 243-255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590376
[Journal Article] A case of epithelial-myoepithelial carcinoma of the bronchus. a review of reported cases and a comparison with other salivary gland-type carcinomas of the bronchus2010
- Author(s)
  Okudela K, Yazawa T, Tajiri M, Omori T, Takahashi K, Woo T, Shimoyamada H, Ogawa N, Kitamura H
- Journal Title
  
  Pathol Res Pract
  
  Volume: 206 Pages: 121-129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590376
[Journal Article] Early growth response-1 induces and enhances vascular endothelial Growth factor-A expression in lung cancer cells2010
- Author(s)
  下山田博明
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 177 Pages: 70-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590366
[Journal Article] Early growth response-1 induces and enhances vascular endothelial growth factor-A expression in lung cancer cells.2010
- Author(s)
  Shimoyamada H, Yazawa T, Sato H, Okudela K, Ishii J, Sakaeda M, Kashiwagi K, Suzuki T, Mitsui H, Woo T, Tajiri M, Ohmori T, Ogura T, Masuda M, Oshiro H, Kitamura H
- Journal Title
  
  Am J Pathol
  
  Volume: 177(1) Pages: 70-83
- Data Source
  KAKENHI-PROJECT-22590366
[Journal Article]2009
- Author(s)
  Yazawa T, Sato H, Shimoyamada H, Okudela K, Woo T, Tajiri M, Ogura T, Ogawa N, Suzuki T, Mitsui H, Ishii J, Miyata C, Sakaeda M, Goto K, Kashiwagi K, Masuda M, Takahashi T, Kitamura H.
- Journal Title
  
  Am J Pathol
  
  Volume: 175 Pages: 976-987
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590376
[Journal Article] Neuroendocrine cancer-specific up-regulating mechanism of insulin-like growth factor binding protein-2 in small cell lung cancer2009
- Author(s)
  Yazawa T, Sato H, Shimoyamada H, Okudela K, Woo T, Tajiri M, Ogura T, Ogawa N, Suzuki T, Mitsui H, Ishii J, Miyata C, Sakaeda M, Goto K, Kashiwagi K, Masuda M, Takahashi T, Kitamura H.
- Journal Title
  
  Am J Pathol (in press)
- Data Source
  KAKENHI-PROJECT-19590358
[Journal Article] Down-regulation of DUSP6 expression in lung cancers-its mechanism and potential role in carcinogenesis2009
- Author(s)
  Okudela K, Yazawa T, Woo T, Sakaeda M, Ishii J, Shimoyamada H, Sato H, Tajiri M, Ogawa N, Masuda M, Takahashi T, Sugimura H, Kitamura H.
- Journal Title
  
  Am J Pathol (in press)
- Data Source
  KAKENHI-PROJECT-19590358
[Journal Article] Small cell lung cancer : significance of RB alterations and TTF-1 expression in its carcinogenesis, phenotype, and biology2009
- Author(s)
  Kitamura H, Yazawa T, Sato H, Okudela K, Shimoyamada H.
- Journal Title
  
  Endocr Pathol 20
  
  Pages: 101-107
- Data Source
  KAKENHI-PROJECT-19590358
[Journal Article] Down-regulation of FXYD3 expression in human lung cancers : its mechanism and potential role in carcinogenesis2009
- Author(s)
  Okudela K, Yazawa T, Ishii J, Woo T, Mitsui H, Bunai T, Sakaeda M, Shimoyamada H, Sato H, Tajiri M, Ogawa N, Masuda M, Sugimura H, Kitamura H.
- Journal Title
  
  Am J Pathol
  
  Volume: 175 Pages: 2646-2656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590376
[Journal Article] Neuroendocrine cancer-specific up-regulating mechanism of insulin-like growth factor binding protein-2 in small cell lung cancer2009
- Author(s)
  Yazawa T, Sato H, Shimoyamada H, Okudela K, et al.
- Journal Title
  
  American Journal of Pathology 175
  
  Pages: 976-987
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590376
[Journal Article] Down-regulation of DUSP6 expression in lung cancer : its mechanism and potential role in carcinogenesis2009
- Author(s)
  Okudela K, Yazawa T, Woo T, Sakaeda M, Ishii J, Mitsui H, Shimoyamada H, Sato H, Tajiri M, Ogawa N, Masuda M, Takahashi T, Sugimura H, Kitamura H.
- Journal Title
  
  Am J Pathol
  
  Volume: 175 Pages: 867-881
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590376
[Journal Article] A case of epithelial-myoepithelial carcinoma of the bronchus-a review of reported cases and a comparison with other salivary gland-type carcinomas of the bronchus2009
- Author(s)
  Okudela K, Yazawa T, Tajiri M, Omori T, Takahashi K, Woo T, Shimoyamada H, Ogawa N, Kitamura H.
- Journal Title
  
  Pathol Res Pract (in press)
- Data Source
  KAKENHI-PROJECT-19590358
[Journal Article] Cancer stem cell : implications in cancer biology and therapy with special reference to lung cancer2009
- Author(s)
  Kitamura H, Okudela K, Yazawa T, Sato H, Shimoyamada H.
- Journal Title
  
  Lung Cancer
  
  Volume: 66 Pages: 275-281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590376
[Journal Article] Growth regulation via insulin-like growth factor binding protein-4 and -2 in association with mutant k-ras in lung epithelia.2006
- Author(s)
  Sato H, Yazawa T, Shimoyamada H, Kitamura H et al.
- Journal Title
  
  American Journal of Pathology 169巻5号
  
  Pages: 1550-1566
- NAID
  40015536016
- Data Source
  KAKENHI-PROJECT-18659098
[Journal Article] Growth regulation via insulin-like growth factor binding protein-4 and -2 in association with mutant K-ras in lung epithelia.2006
- Author(s)
  Sato H, Yazawa T, Shimoyamada H et al.
- Journal Title
  
  American Journal of Pathology 169巻5号
  
  Pages: 1550-1566
- Data Source
  KAKENHI-PROJECT-17790242
[Presentation] 肺の神経内分泌系悪性腫瘍とIII/IV型POU遺伝子2014
- Author(s)
  石井　順、矢澤卓也、佐藤華子、宍戸-原由紀子、平松千恵、下山田博明、藤原正親、菅間　博
- Organizer
  第103回日本病理学会総会
- Place of Presentation
  広島国際会議場（広島県・広島市）
- Year and Date
  2014-04-24
- Data Source
  KAKENHI-PROJECT-24590428
[Presentation] POU型転写因子BRN2は肺小細胞癌細胞の神経/神経内分泌形質発現および増殖活性に関与する2013
- Author(s)
  石井順、佐藤華子、榮田昌史、原由紀子、平松千恵、菅間博、下山田博明、藤原正親、遠藤哲哉、青木一郎、矢澤卓也
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590428
[Presentation] 肺小細胞癌におけるTTF-1発現はPOUドメイン転写因子BRN2により直接的に制御されている2013
- Author(s)
  榮田昌史、佐藤華子、石井順、菅間博、原由紀子、平松千恵、下山田博明、藤原正親、遠藤哲哉、矢澤卓也
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590428
[Presentation] 肺神経内分泌腫瘍におけるBRN2、ASCL1、TTF1の発現性の検討2013
- Author(s)
  遠藤哲哉、石井順、榮田昌史、藤原正親、宍戸-原由紀子、下山田博明、平野和彦、寺戸雄一、菅間博、矢澤卓也
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590428
[Presentation] 甲状腺癌においてTTF-1により発現変化する遺伝子の網羅的解析2012
- Author(s)
  下山田博明, 大森嘉彦, 榮田昌史, 有益優, 石井順, 矢澤卓也, 菅間博
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Year and Date
  2012-04-28
- Data Source
  KAKENHI-PROJECT-21590376
[Presentation] 肺癌の神経／神経内分泌形質にASCL1およびRESTが与える影響の解析2012
- Author(s)
  石井順、有益優、榮田昌史、柏木維人、下山田博明、佐藤華子、宮田千恵、藤原正親、菅間博、青木一郎、矢澤卓也
- Organizer
  第101日本病理学会総会
- Place of Presentation
  新宿、東京都
- Data Source
  KAKENHI-PROJECT-24590428
[Presentation] 肺癌におけるThyroid transcription factor-1の発現機序に関与する因子の検索2012
- Author(s)
  榮田昌史、佐藤華子、宮田千恵、石井順、有益優、柏木維人、下山田博明、菅間博、青木一郎、矢澤卓也
- Organizer
  第101日本病理学会総会
- Place of Presentation
  新宿、東京都
- Data Source
  KAKENHI-PROJECT-24590428
[Presentation] 肺癌におけるThyroid Transcription Factor-1の発現機序に関与する因子の検索2012
- Author(s)
  榮田昌史, 佐藤華子, 宮田千恵, 石井順, 有益優, 柏木維人, 下山田博明, 菅間博, 青木一郎, 矢澤卓也
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Year and Date
  2012-04-27
- Data Source
  KAKENHI-PROJECT-21590376
[Presentation] 甲状腺癌においてTTF-1により発現変化する遺伝子の網羅的解析2012
- Author(s)
  下山田博明
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590366
[Presentation] 肺癌の神経/神経内分泌形質にASCL1およびRESTが与える影響の解析2012
- Author(s)
  石井順, 有益優, 榮田昌史, 柏木維人, 下山田博明, 佐藤華子, 宮田千恵, 藤原正親, 菅間博, 青木一郎, 矢澤卓也
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Year and Date
  2012-04-27
- Data Source
  KAKENHI-PROJECT-21590376
[Presentation] 気管支の上皮筋肉上皮腫の一例2011
- Author(s)
  奥寺康司、矢澤卓也、田尻道彦、下山田博明、北村均
- Organizer
  日本病理学会総会（第１００回）
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23590428
[Presentation] 神経内分泌マーカー発現に対するNeuroD, ASCL1の関与について2011
- Author(s)
  柏木維人, 石井順, 榮田昌史, 有益優, 佐藤華子, 奥寺康司, 下山田博明, 矢澤卓也
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  横浜
- Year and Date
  2011-04-28
- Data Source
  KAKENHI-PROJECT-21590376
[Presentation] 神経内分泌マーカー発現に対するNeuroD, ASCL1の関与について2011
- Author(s)
  柏木維人, 石井順, 榮田昌史, 有益優, 佐藤華子, 奥寺康司, 下山田博明, 矢澤卓也
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2011-04-28
- Data Source
  KAKENHI-PROJECT-21590376
[Presentation] 肺癌細胞におけるNeuroD発現はNeural Cell Adhesion Molecule 1(NCAM1)を誘導する2010
- Author(s)
  柏木維人, 石井順, 榮田昌史, 佐藤華子, 奥寺康司, 下山田博明, 北村均, 矢澤卓也
- Organizer
  第99回日本病理学会総会
- Place of Presentation
  東京
- Year and Date
  2010-04-28
- Data Source
  KAKENHI-PROJECT-21590376
[Presentation] IGFBP-4 expression deficiency by epigenetic silencing in non-small cell lung cancers2010
- Author(s)
  佐藤華子, 榮田昌史, 石井順, 柏木維人, 奥寺康司, 下山田博明, 北村均, 矢澤卓也
- Organizer
  第99回日本病理学会総会
- Place of Presentation
  東京
- Year and Date
  2010-04-28
- Data Source
  KAKENHI-PROJECT-21590376
[Presentation] An altered histological sub-typing system for lung adenocarcinoma2010
- Author(s)
  奥寺康司, .哲漢, 三井秀昭, 矢澤卓也, 下山田博明, 田尻道彦, 小川伸郎, 益田宗孝, 北村均
- Organizer
  第99回日本病理学会総会
- Place of Presentation
  東京
- Year and Date
  2010-04-28
- Data Source
  KAKENHI-PROJECT-21590376
[Presentation] 癌におけるインスリン様増殖因子結合蛋白-2(IGFBP-2)およびIGFBP-4の発現現弱機構の解析2009
- Author(s)
  佐藤華子, 矢澤卓也, 下山田博明, 奥寺康司, 榮田昌史, 石井順, 宮田千恵, 後藤和哉, 柏木維人, 北村均
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  京都
- Year and Date
  2009-05-02
- Data Source
  KAKENHI-PROJECT-21590376
[Presentation] 肺腺癌におけるTTF-1遺伝子プロモーターのメチル化解析2009
- Author(s)
  矢澤卓也, 佐藤華子, 宮田千恵, 下山田博明, 奥寺康司, 石井順, 榮田昌史, 後藤和哉, 柏木維人, 北村均
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  京都
- Year and Date
  2009-05-02
- Data Source
  KAKENHI-PROJECT-21590376
[Presentation] がん細胞の異型性の分子基盤(イオンチャンネル制御因子FXYD3の関与)2009
- Author(s)
  奥寺康司, 矢澤卓也, 下山田博明, .哲漢, 佐藤華子, 竹内智康, 石井順, 榮田昌史, 後藤和哉, 宮田千恵, 柏木維人, 椙村春彦, 北村均
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  京都
- Year and Date
  2009-05-02
- Data Source
  KAKENHI-PROJECT-21590376
[Presentation] ヒト肺腺癌におけるVEGF-Aの発現機序におけるNAB2, egr-1の役割の解明2009
- Author(s)
  下山田博明, 矢澤卓也, 佐藤華子, 奥寺康司, 宮田千恵, 榮田昌史, 石井順, 後藤和哉, 柏木維人, 北村均
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  京都
- Year and Date
  2009-05-02
- Data Source
  KAKENHI-PROJECT-21590376

1. YAZAWA Takuya (50251054)

# of Collaborated Projects: 6 results

# of Collaborated Products: 44 results
2. OKUDELA Koji (10326027)

# of Collaborated Projects: 4 results

# of Collaborated Products: 32 results
3. KITAMURA Hitoshi (20094302)

# of Collaborated Projects: 3 results

# of Collaborated Products: 21 results
4. SATO Hanako (60438132)

# of Collaborated Projects: 3 results

# of Collaborated Products: 37 results
5. KATAYA Akira (10333113)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NAGAHARA Noriyuki (10208043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. WOO Tetsukan (90537177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HARA Yukiko (40313267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. FUJIWARA Masachika (20407026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
10. KAMMA Hiroshi (10195191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
11. ISHII Jun

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
12. SAKAEDA Masashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results

Shimoyamada Hiroaki 下山田 博明

SHIMOYAMADA Hiroaki 下山田 博明

Research Projects

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Co-Researchers

Molecular pathological analyses of proneural/neuroendocrine phenotype-obtaining mechanisms on lung cancer cells

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The molecular basis of morphological atypism (proteome analysis of KRAS downstream factors)

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Therapeutic approach to lung cancer and malignant mesothelioma by inhibition of VEGR-VEGFR pathwayPrincipal Investigator

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Analysis of expression mechanisms of neuroendocrine cancer cell-specific molecules via TTF-1

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Exhaustive search for onco-suppressor genes induced by Egr-1 and cause-analysis of their repression in association with carcinogenesis

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肺小細胞癌において高発現するインスリン様増殖因子結合蛋白2の発現機序及び機能解析

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肺癌の胸幹播種・癌性リンパ管症における血管内皮増殖因子の関与とその治療法の解明Principal Investigator

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[Book] 臨床画像No.92012

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[Journal Article] Expression of developing neural transcription factors in lung carcinoid tumors2014

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[Journal Article] POU domain transcription factor BRN2 is crucial for expression of ASCL1, ND1 and neuroendocrine marker molecules and cell growth in small cell lung cancer2013

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[Journal Article] POU domain transcription factor BRN2 is crucial for expression of ASCL1, ND1 and neuroendocrine marker molecules and cell growth in small cell lung cancer2013

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[Journal Article] Neural lineage-specific homeoprotein BRN2 is directly involved in TTF1 expression in small-cell lung cancer2013

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[Journal Article] Neural lineage-specific homeoprotein BRN2 is directly involved in TTF1 expression in small-cell lung cancer2013

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[Journal Article]2013

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[Journal Article] Differences of molecular expression mechanisms among neural cell adhesion molecule 1, synaptophysin, and chrmogranin A in lung cancer cells2012

Author(s)

Shimoyamada Hiroaki 下山田博明

SHIMOYAMADA Hiroaki 下山田博明