IMAI Kenichi 今井健一

Researcher Number	60381810
Other IDs
Affiliation (Current)	2025: 日本大学, 歯学部, 教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 日本大学, 歯学部, 教授 2011 – 2014: 日本大学, 歯学部, 准教授 2010 – 2011: 日本大学, 歯学部, 講師 2008: Nagoya City University, 大学院・医学研究科, 助教 2007: Nagoya City University, 大学院・医学研究科, 研究員 2005 – 2006: 名古屋市立大学, 大学院医学研究科, 研究員
Review Section/Research Field	Principal Investigator Virology / Pathobiological dentistry/Dental radiology / Medium-sized Section 57:Oral science and related fields / Basic Section 57080:Social dentistry-related / Basic Section 57020:Oral pathobiological science-related Except Principal Investigator Social dentistry / Basic Section 57080:Social dentistry-related / Morphological basic dentistry
Keywords	Principal Investigator 歯周病 / ウイルス / 潜伏感染 / 根尖性歯周炎 / EBV / 炎症性サイトカイン / 転写 / HDAC / HIV / EBウイルス … More / 歯周疾患 / ＥＢＶ / エピジェネティクス / AP-4 / 口腔ケア / 誤嚥性肺炎 / 口腔健康管理 / インフルエンザ / 慢性閉塞性肺疾患 / COVID-19 / 肺炎 / 歯周病原菌 / ＬＭＰ１ / BZLF1 / 唾液 / 破骨細胞 / NOGマウス / 炎症性サイトカイン」 / インプラント周囲炎 / 炎症 / P. gingivaｌis / メチル化 / エピジェネティック / HDA / ヒストン / G9a / 酪酸 / HIV/AIDS / エノズ / AIDS / repression / TATA box / TBP / HIV-1 / 転写抑制 … More Except Principal Investigator ランチビオテックスバクテリオシン / ランチビオテックス / ランチビオテクス / 口腔内細菌 / バクテリオシン / ミュータンス菌 / Porphyromonas gingivalis / ジンジパイン / 口腔細菌 / インフルエンザウイルス / 膣内細菌 / 腸内細菌叢 / HIV / エピジェネティク制御 / n-酪酸 / 短鎖脂肪酸 / 歯周病 / 微生物間相互作用 / ウイルス / HDAC / 酸化ストレス / EBV / エピジェネティクス / 酪酸 / 老化微生物 / カテキン / 老化 / 口腔微生物 / 歯学 / 衛生 / 医療・福祉 / 口腔ケア Less

歯周病発症機序のパラダイムシフトへの挑戦ーヒト化マウスでのウイルス関与の立証ーPrincipal Investigator
- Principal Investigator
  
  今井健一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Nihon University
Strategic approach towards etiological elucidation and novel therapeutic and prophylactic development of lower respiratory diseases due to aspiration of periodontopathic bacteriaPrincipal Investigator
- Principal Investigator
  
  今井健一
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Nihon University
Analysis of the possibility that colonization of bacteriocin-producing bacteria in the oral cavity may cause intestinal microbiota dysbiosis
- Principal Investigator
  
  Hideo Yonezawa
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Tokyo Dental College
  Kyorin University
A strategic approach to elucidate the etiology of EBV-induced periodontitis and to develop novel therapiesPrincipal Investigator
- Principal Investigator
  
  IMAI Kenichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Nihon University
Strategic approach towards etiological elucidation and novel therapy development of periodontitis attributed to EBVPrincipal Investigator
- Principal Investigator
  
  IMAI Kenichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nihon University
Study on the effects of oral bacteria in influenza virus infection
- Principal Investigator
  
  KAMIO Noriaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Social dentistry
- Research Institution
  Nihon University
Etiological elucidation of periodontal disease attributed to EBVPrincipal Investigator
- Principal Investigator
  
  IMAI kenichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nihon University
Effects of butyric acid producing bacteria on epigenetic gene regulation and systemic diseases
- Principal Investigator
  
  OCHIAI Kuniyasu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nihon University
Elucidation of molecular mechanisms HIV viral latency and its reactivation involving epigenetic regulationPrincipal Investigator
- Principal Investigator
  
  IMAI Kenichi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  Nihon University
Possibility of the oral microorganism control in the elderly by a gel-entrapped catechin
- Principal Investigator
  
  TAMURA Muneaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Social dentistry
- Research Institution
  Nihon University
Role of transcriptional factor AP-4 in the maintenance of HIV-1 latencyPrincipal Investigator
- Principal Investigator
  
  IMAI Kenichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  Nagoya City University
転写因子AP-4によるHIV遺伝子発現抑制機構の解明Principal Investigator
- Principal Investigator
  
  今井健一
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  Nagoya City University

[Book] 口腔微生物学　感染と免疫2021
- Author(s)
  石原和幸、今井健一、大島朋子、落合智子、葛城啓彰、清浦有祐、高橋幸裕、田中芳彦、浜田信城、
- Total Pages
  423
- Publisher
  学建書院
- Data Source
  KAKENHI-PROJECT-19K10078
[Book] 口腔微生物学－感染と免疫－　第6版2018
- Author(s)
  石原和幸今井健一小川知彦落合邦康落合智子葛城啓彰上西秀則清浦有祐古西清田中芳彦中澤太浜田信城前田伸子
- Total Pages
  433
- Publisher
  学研書院
- Data Source
  KAKENHI-PROJECT-16K11526
[Book] 腸内細菌・口腔細菌と全身疾患2015
- Author(s)
  神尾宜昌, 今井健一, 田村宗明, 落合邦康他
- Total Pages
  259
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-15K11430
[Book] 化学療法の領域　「口腔内細菌とウイルス感染症　-歯周病原菌によるエピジェネティック制御を介する潜伏HIVの再活性化機構-」2011
- Author(s)
  今井健一
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] Fusobacterium nucleatum exacerbates chronic obstructive pulmonary disease in elastase-induced emphysematous mice.2022
- Author(s)
  Suzuki R, Kamio N, Kaneko T, Yonehara Y, Imai K.
- Journal Title
  
  FEBS Open Bio.
  
  Volume: 12(3) Issue: 3 Pages: 638-648
- DOI
  10.1002/2211-5463.13369
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10078, KAKENHI-PROJECT-21K10265
[Journal Article] Porphyromonas gingivalis Mfa1 fimbria putatively binds to TLR2 and induces both IL-6 and IL-8 production in human bronchial epithelial cells.2022
- Author(s)
  Takahashi Y, Cueno ME, Kamio N, Iinuma T, Hasegawa T, Imai K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 589 Pages: 35-40
- DOI
  10.1016/j.bbrc.2021.12.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10078, KAKENHI-PROJECT-20K09931, KAKENHI-PROJECT-21K10265
[Journal Article] Epstein-Barr Virus Promotes the Production of Inflammatory Cytokines in Gingival Fibroblasts and RANKL-Induced Osteoclast Differentiation in RAW264.7 Cells.2022
- Author(s)
  Yokoe S, Hasuike A, Watanabe N, Tanaka H, Karahashi H, Wakuda S, Takeichi O, Kawato T, Takai H, Ogata Y, Sato S, Imai K
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 23(2) Issue: 2 Pages: 80-80
- DOI
  10.3390/ijms23020809
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10078, KAKENHI-PROJECT-20K09945, KAKENHI-PROJECT-20K09980
[Journal Article] Expression of the SARS-CoV-2 Receptor ACE2 and Proinflammatory Cytokines Induced by the Periodontopathic Bacterium Fusobacterium nucleatum in Human Respiratory Epithelial Cells2021
- Author(s)
  Takahashi Y, Watanabe N, Kamio N, Yokoe S, Suzuki R, Sato S, Iinuma T, Imai K
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 22(3) Issue: 3 Pages: 1352-1352
- DOI
  10.3390/ijms22031352
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10078, KAKENHI-PROJECT-18K09920
[Journal Article] Analysis of the Interaction Between HIV and Periodontopathic Bacteria That Reactivates HIV Replication in Latently Infected Cells.2021
- Author(s)
  Imai K.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 2210 Pages: 207-214
- DOI
  10.1007/978-1-0716-0939-2_20
- ISBN
  9781071609385, 9781071609392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10078
[Journal Article] Relationship between the oral cavity and respiratory diseases: Aspiration of oral bacteria possibly contributes to the progression of lower airway inflammation.2021
- Author(s)
  Imai K, Iinuma T, Sato S.
- Journal Title
  
  Jap. Dent. Sci. Rev.
  
  Volume: 53 Pages: 224-230
- DOI
  10.1016/j.jdsr.2021.10.003
- NAID
  210000172915
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10078
[Journal Article] 口腔と全身疾患研究の最前線　はじめに2021
- Author(s)
  今井健一
- Journal Title
  
  医学のあゆみ
  
  Volume: 277(12) Pages: 1009-1010
- Data Source
  KAKENHI-PROJECT-19K10078
[Journal Article] Aspiration of periodontopathic bacteria due to poor oral hygiene potentially contributes to the aggravation of COVID-192021
- Author(s)
  Takahashi Y, Watanabe N, Kamio N, Kobayashi R, Iinuma T, Imai K
- Journal Title
  
  Journal of Oral Science
  
  Volume: 63 Issue: 1 Pages: 1-3
- DOI
  10.2334/josnusd.20-0388
- NAID
  130007959227
- ISSN
  1343-4934, 1880-4926
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10078, KAKENHI-PROJECT-18K09920
[Journal Article] Structural Comparison of the SARS CoV 2 Spike Protein Relative to Other Human-Infecting Coronaviruses2021
- Author(s)
  Cueno ME, Imai K
- Journal Title
  
  Front Medicine
  
  Volume: 7 Pages: 594439-594439
- DOI
  10.3389/fmed.2020.594439
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10078, KAKENHI-PROJECT-19K10097
[Journal Article] Insights on the structural variations of the furin-like cleavage site found among the December, 2019-July, 2020 SARS-CoV-2 spike glycoprotein: A computational study linking viral evolution and infection.2021
- Author(s)
  Cueno ME, Ueno M, Iguchi R, Harada T, Miki Y, Yasumaru K, Kiso N, Wada K, Baba K, Imai K.
- Journal Title
  
  Front Medicine
  
  Volume: 8 Pages: 613412-613412
- DOI
  10.3389/fmed.2021.613412
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10078, KAKENHI-PROJECT-19K10097
[Journal Article] Porphyromonas gingivalis enhances pneumococcal adhesion to human alveolar epithelial cells by increasing expression of host platelet-activating factor receptor.2021
- Author(s)
  Kamio N, Hayata M, Tamura M, Tanaka H, Imai K
- Journal Title
  
  FEBS Lett
  
  Volume: in press Issue: 11 Pages: 1604-1612
- DOI
  10.1002/1873-3468.14084
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10078, KAKENHI-PROJECT-18K09920, KAKENHI-PROJECT-21K10219
[Journal Article] Butyric Acid in Saliva of Chronic Periodontitis Patients Induces Transcription of the EBV Lytic Switch Activator BZLF1: A Pilot Study.2020
- Author(s)
  Koike R, Nodomi K, Watanabe N, Ogata Y, Takeichi O, Takei M, Kaneko T, Tonogi M, Kotani AI, Imai K
- Journal Title
  
  in Vivo
  
  Volume: 34 Issue: 2 Pages: 587-594
- DOI
  10.21873/invivo.11811
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11994, KAKENHI-PROJECT-19K10078
[Journal Article] Structural insights into the potential changes in receptor binding site found in the 1998-2018 influenza B/Yamagata hemagglutinin: A putative correlation between receptor binding site structural variability and seasonal infection.2020
- Author(s)
  1.Cueno ME, Iguchi K, , Suemitsu K, Hirano M, Hanzawa K, Isoda T, Ueno M, Iguchi R, Otani A, Imai K
- Journal Title
  
  J. Mol. Graph. Model
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10078
[Journal Article] Epstein-Barr virus reactivation by persistent apical periodontal pathogens2020
- Author(s)
  Himi K, Takeichi O, Imai K, Hatori K, Tamura T, Ogiso B
- Journal Title
  
  Int Endod J
  
  Volume: 53 Pages: 492-505
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10078
[Journal Article] EBV LMP1 in gingival epithelium potentially contributes to human chronic periodontitis via inducible IL8 production2019
- Author(s)
  Watanabe N, Nodomi K, Koike R, Kato A, Takeichi O, Kotani A, Kaneko T, Sakagami H, Takei M, Ogata Y, Sato S, Imai K
- Journal Title
  
  In Vivo
  
  Volume: 33 Pages: 1793-1800
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10078
[Journal Article] Singlet oxygen generated by a new nonthermal atmospheric pressure air plasma device exerts a bactericidal effect on oral pathogens.2019
- Author(s)
  Hirano Y, Hayashi M, Tamura M, Yoshino F, Yoshida A, Masubuchi M, Imai K, Ogiso B
- Journal Title
  
  J Oral sci
  
  Volume: 61 Pages: 521-525
- NAID
  130007751580
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10078
[Journal Article] Cynaropicrin from Cynara scolymus L. suppresses Porphyromonas gingivalis LPS-induced production of inflammatory cytokines in human gingival fibroblasts and RANKL-induced osteoclast differentiation in RAW264.7 cells.2019
- Author(s)
  Hayata M, Watanabe N, Kamio N, Tamura M, Nodomi K, Tanaka K, Iddamalgoda A, Tsuda H, Ogata Y, Sato S, Ueda K, Imai K
- Journal Title
  
  J Nat Med
  
  Volume: 73 Pages: 114-123
- NAID
  40021790096
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10078
[Journal Article] The periodontopathic bacterium Fusobacterium nucleatum induced proinflammatory cytokine Ppoduction by human respiratory epithelial cell lines and in the lower respiratory organs in Mice.2019
- Author(s)
  Hayata M, Watanabe N, Tamura M, Kamio N, Tanaka H, Nodomi K, Miya C, Nakayama E, Ueda K, Ogata Y, Imai K
- Journal Title
  
  Cell Physiol Biochem
  
  Volume: 53 Pages: 49-61
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10078
[Journal Article] Network analytics approach towards identifying potential antivirulence drug targets within the Staphylococcus aureus staphyloxanthin biosynthetic network2018
- Author(s)
  Marni E. Cueno, Kenichi Imai
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: 645 Pages: 81-86
- DOI
  10.1016/j.abb.2018.03.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11525, KAKENHI-PROJECT-16K11526
[Journal Article] Various cellular components change as the rat ages: An insight into the putative overall age-related cellular stress network2018
- Author(s)
  Cueno ME, Imai K
- Journal Title
  
  Experimental Gerontology
  
  Volume: 102 Pages: 36-42
- DOI
  10.1016/j.exger.2017.11.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11525, KAKENHI-PROJECT-16K11526
[Journal Article] Porphyromonas endodontalis reactivates latent Epstein-Barr virus.2018
- Author(s)
  Makino K, Takeichi O, Imai K, Inoue H, Hatori K, Himi K, Saito I, Ochiai K, Ogiso B
- Journal Title
  
  International Endodontic Journal
  
  Volume: 51 Issue: 12 Pages: 1410-1419
- DOI
  10.1111/iej.12959
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11717, KAKENHI-PROJECT-16K01830, KAKENHI-PROJECT-16K11526
[Journal Article] 歯周病の病因に関する最近の話題－細菌とウイルスの相互作用－.2018
- Author(s)
  1.今井健一
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 69 Pages: 180-185
- NAID
  40021473960
- Data Source
  KAKENHI-PROJECT-16K11526
[Journal Article] Cynaropicrin from Cynara scolymus L. suppresses Porphyromonas gingivalis LPS-induced production of inflammatory cytokines in human gingival fibroblasts and RANKL-induced osteoclast differentiation in RAW264.7 cells2018
- Author(s)
  Hayata Mayumi、Watanabe Norihisa、Kamio Noriaki、Tamura Muneaki、Nodomi Keiko、Tanaka Kiyotaka、Iddamalgoda Arunasiri、Tsuda Hiromasa、Ogata Yorimasa、Sato Shuichi、Ueda Kouichiro、Imai Kenichi
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: 73 Issue: 1 Pages: 114-123
- DOI
  10.1007/s11418-018-1250-6
- NAID
  40021790096
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09892, KAKENHI-PROJECT-18K09920, KAKENHI-PROJECT-17K11994, KAKENHI-PROJECT-16K11526
[Journal Article] Periodontal disease level-butyric acid putatively contributes to the ageing blood: A proposed link between periodontal diseases and the ageing process.2017
- Author(s)
  Cueno ME, Seki K, Ochiai K, Imai K
- Journal Title
  
  Mech Ageing
  
  Volume: 162 Pages: 100-105
- DOI
  10.1016/j.mad.2017.01.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11526
[Journal Article] Bactericidal effect of hydroxyl radicals generated by the sonolysis and photolysis of hydrogen peroxide for endodontic applications2017
- Author(s)
  Ibi H, Hayashi M, Yoshino F, Tamura M, Yoshida A, Kobayashi Y, Shimizu K, Lee M-C, Imai K, Ogiso B
- Journal Title
  
  Microbial Pathogenesis
  
  Volume: 103 Pages: 65-70
- DOI
  10.1016/j.micpath.2016.12.010
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21454, KAKENHI-PROJECT-16K11901, KAKENHI-PROJECT-16K11526, KAKENHI-PROJECT-16K11566, KAKENHI-PROJECT-15K11275
[Journal Article] Prevalence of Epstein-Barr virus DNA and Porphyromonas gingivalis in Japanese peri-implantitis patients.2017
- Author(s)
  Kato A, Imai K, Sato H, Ogata Y
- Journal Title
  
  BMC Oral Health
  
  Volume: 17（１） Issue: 1 Pages: 148-148
- DOI
  10.1186/s12903-017-0438-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11526
[Journal Article] 歯周病の発症と進行へのウイルス感染の関与の可能性2016
- Author(s)
  小方頼昌, 加藤彩子, 今井健一, 落合邦康
- Journal Title
  
  千葉県歯科医学会誌
  
  Volume: 6 Pages: 8-11
- Data Source
  KAKENHI-PROJECT-16K11526
[Journal Article] Structural Significance of the β1K396 Residue Found in the Porphyromonas gingivalis Sialidase β-Propeller Domain: A Computational Study with Implications for Novel Therapeutics Against Periodontal Disease.2014
- Author(s)
  Cueno ME, Kamio N, Imai K, Ohya M, Tamura M, Ochiai K
- Journal Title
  
  OMICS : A Journal of Integrative Biology
  
  Volume: 18 Pages: 591-599
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592843
[Journal Article] 細菌・ヘルペスウイルス共感染による歯周病進行の可能性.2014
- Author(s)
  小方頼昌, 加藤彩子, 今井健一, 落合邦康
- Journal Title
  
  日本歯周病学会誌
  
  Volume: 56 Pages: 267-271
- NAID
  130004842576
- Data Source
  KAKENHI-PROJECT-24592843
[Journal Article] Butyric acid-induced rat jugular blood cytosolic oxidative stress is associated with SIRT1 decrease.2014
- Author(s)
  Cueno ME, Imai K, Tamura M, Ochiai K
- Journal Title
  
  Cell Stress Chaperon
  
  Volume: 19 Issue: 2 Pages: 295-298
- DOI
  10.1007/s12192-013-0462-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23592714, KAKENHI-PROJECT-24593168
[Journal Article] Role of the histone H3 lysine 9 methyltransferase Suv39 h1 in maintaining Epsteinn-Barr virus latency in B95-8 cells.2014
- Author(s)
  Imai K, Kamio N, Cueno ME, Saito Y, Inoue H, Saito I, Ochiai K.
- Journal Title
  
  The FEBS journal
  
  Volume: 281 Issue: 9 Pages: 2148-2158
- DOI
  10.1111/febs.12768
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592783, KAKENHI-PROJECT-24592843, KAKENHI-PROJECT-24792010
[Journal Article] Butyric acid-induced rat jugular blood cytosolic oxidative stress is associated with SIRT1 decrease.2014
- Author(s)
  Cueno ME, Imai K, Tamura M, Ochiai K
- Journal Title
  
  Cell Stress Chaperones
  
  Volume: 19 Pages: 295-298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592843
[Journal Article] 歯周疾患の発症と進展におけるウイルスの関与第3回：ウイルスと歯周病との関連2013
- Author(s)
  小方頼昌, 加藤彩子, 今井健一, 落合邦康
- Journal Title
  
  日本歯科評論
  
  Volume: 73 Pages: 143-145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] Butyric acid retension in gingival tissue induces oxidative stress in jugular blood mitochondria2013
- Author(s)
  Marni E. Cueno
- Journal Title
  
  Cell Stress and Chaperones
  
  Volume: 18 Issue: 5 Pages: 661-665
- DOI
  10.1007/s12192-013-0409-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390398, KAKENHI-PROJECT-23592714, KAKENHI-PROJECT-24592843, KAKENHI-PROJECT-24792010
[Journal Article] Overlapping glycosylation sequon influences the glycosylation pattern of a chimeric protein expressed in tomato leaf and callus2013
- Author(s)
  Cueno ME, Imai K, Okamoto T, Ochiai K
- Journal Title
  
  J Biotechnol
  
  Volume: 164 Issue: 1 Pages: 9-12
- DOI
  10.1016/j.jbiotec.2012.12.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714, KAKENHI-PROJECT-24792010
[Journal Article] Homology modeling study toward identifying structural properties in the HA2 B-loop that would influence the HA1 receptor-binding site.2013
- Author(s)
  Cueno ME, Imai K, Shimizu K, Ochiai K
- Journal Title
  
  J Mol Graph Model
  
  Volume: 44 Pages: 161-167
- DOI
  10.1016/j.jmgm.2013.05.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592843, KAKENHI-PROJECT-24792010
[Journal Article] Higher prevalence of Epstein-Barr virus DNA in deeper periodontal pockets of chronic periodontitis in Japanese patients2013
- Author(s)
  Kato A, Imai K, Ochiai K, Ogata Y
- Journal Title
  
  PLOS ONE
  
  Volume: 8 Issue: 8 Pages: 1-5
- DOI
  10.1371/journal.pone.0071990
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714, KAKENHI-PROJECT-24592843, KAKENHI-PROJECT-25463229
[Journal Article] BIX01294 suppresses osteoclast differentiation on mouse macrophage-like Raw264.7 cells2013
- Author(s)
  Tsuda H, Zhao N, Imai K, Ochiai K, Yang P, Suzuki N
- Journal Title
  
  Bosn J Basic Med Sci
  
  Volume: 13 Pages: 271-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] Interaction between endogenous bacterial flora and latent HIV infection.2013
- Author(s)
  Victriano AF, Imai k, Okamoto T
- Journal Title
  
  Clin Vaccine Immunol.
  
  Volume: 20(6) Issue: 6 Pages: 773-779
- DOI
  10.1128/cvi.00766-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592843
[Journal Article] 歯周疾患の発症と発展におけるウイルスの関与第2回：根尖性歯周炎とヘルペスウイルス感染2013
- Author(s)
  武市収, 小木曽文内, 今井健一, 落合邦康
- Journal Title
  
  日本歯科評論
  
  Volume: 73 Pages: 130-132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] Effect of microbial coinfection with HIV-1 and butyric acid-producing anaerobic bacteria on AIDS progression2013
- Author(s)
  Imai K,Ochiai K
- Journal Title
  
  J 0ral Biosci
  
  Volume: vol.55 Issue: 2 Pages: 55-60
- DOI
  10.1016/j.job.2013.03.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] 歯周疾患の病因論におけるウイルスの意義2013
- Author(s)
  今井健一, 落合邦康
- Journal Title
  
  日本歯科評論
  
  Volume: 73(7) Pages: 151-153
- Data Source
  KAKENHI-PROJECT-24592843
[Journal Article] Orally supplemented catechin increases heme amounts and catalase activities in rat heart blood mitochondoria: A comparison between middle-aged and young rats2013
- Author(s)
  Cueno ME, Tamura M, Imai K, Ochiai K
- Journal Title
  
  Experimental Gerontology
  
  Volume: 48 Issue: 11 Pages: 1319-1322
- DOI
  10.1016/j.exger.2013.08.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] BIX01294 suppresses osteoclast differentiation on mouse macrophage-like Raw264.7 cells2013
- Author(s)
  Tsuda H,Zhao N,Imai K,Ochiai K,Yang P,Suzuki N
- Journal Title
  
  Bosn J Basic Med Sci
  
  Volume: vol.13 Pages: 271-275
- URL
  http://www.bjbms.org/archives/2013-4/11-Tsuda.pdf#search
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] 歯周疾患の発症と進展におけるウイルスの関与　第１回：歯周疾患の病因論におけるウイルスの意義.2013
- Author(s)
  今井健一，落合邦康
- Journal Title
  
  日本歯科評論
  
  Volume: 73 Pages: 151-153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] Effect of microbial coinfection with HIV-1 and butyric acid-producing anaerobic bacteria on AIDS progression.2013
- Author(s)
  Imai K, Ochiai K
- Journal Title
  
  J. Oral. Biosci.
  
  Volume: 55 Pages: 55-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592843
[Journal Article] The periodontal pathogen Porphyromonas gingivalis induces the Epstein-Barr virus lytic switch transactivator ZEBRA by histone modification2012
- Author(s)
  Imai K
- Journal Title
  
  Biochimie
  
  Volume: 第94巻 Pages: 839-846
- NAID
  10031131378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592664
[Journal Article] 「歯学的医学」の実践を目指して-.2012
- Author(s)
  今井健一他
- Journal Title
  
  日本歯科評論
  
  Volume: 72(10) Pages: 9-11
- Data Source
  KAKENHI-PROJECT-24592843
[Journal Article] 「歯学的医学」の実践を目指して-.2012
- Author(s)
  今井健一他
- Journal Title
  
  日本歯科評論
  
  Volume: 72(10) Pages: 9-11
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] Microbial interaction of periodontopathic bacteria and Epstein–Barr virus and their implication of periodontal diseases.2012
- Author(s)
  Imai K et al.
- Journal Title
  
  J. Oral Biosci.
  
  Volume: 54(3) Issue: 3 Pages: 164-168
- DOI
  10.1016/j.job.2012.07.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714, KAKENHI-PROJECT-24592843
[Journal Article] Cytokinin dehydrogenase differentially regulates cytokinin and indirectly affects hydrogen peroxidase accumulation in tomato leaf.2012
- Author(s)
  Cueno ME et al.
- Journal Title
  
  J. plant. physi
  
  Volume: 169(8) Issue: 8 Pages: 834-838
- DOI
  10.1016/j.jplph.2012.01.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714, KAKENHI-PROJECT-24592843, KAKENHI-PROJECT-24792010
[Journal Article] Reactivation of latent HIV-1 by a wide variety of butyric acid-producing bacteria.2012
- Author(s)
  Imai K et al.
- Journal Title
  
  Cell. Mol. Life Sci.
  
  Volume: 69(15) Issue: 15 Pages: 2583-2592
- DOI
  10.1007/s00018-012-0936-2
- NAID
  10029976312
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714, KAKENHI-PROJECT-24592843
[Journal Article] Reactivation of latent HIV-1 by a wide variety of butyric acid-producing bacteria2012
- Author(s)
  Imai K, Yamada K, Tamura M, Ochiai K, Okamoto T
- Journal Title
  
  Cell. Mol. Life Sci.
  
  Volume: (in press)
- NAID
  10029976312
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790437
[Journal Article] Microbial Interaction of Periodontopathic Bacterium Porphyromonas gingivalis and HIV -Possible Causal Link of Periodontal Diseases to AIDS Progression-2012
- Author(s)
  Imai K et al.
- Journal Title
  
  Current HIV Research
  
  Volume: 10 Issue: 3 Pages: 213-220
- DOI
  10.2174/157016212800618183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714, KAKENHI-PROJECT-24592843
[Journal Article] Microbial interaction between HIV-1 and anaerobic bacteria producing butyric acid: its potential implication in AIDS progression.2012
- Author(s)
  Imai K et al.
- Journal Title
  
  Future virology
  
  Volume: 7(10) Issue: 10 Pages: 1005-1014
- DOI
  10.2217/fvl.12.92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714, KAKENHI-PROJECT-24592843
[Journal Article] The periodontal pathogen Porphyromonas gingivalis induces the Epstein-Barr Virus lytic switch transactivator ZEBRA by histone modification2011
- Author(s)
  Imai K, et al
- Journal Title
  
  Biochimie
  
  Volume: 94(3) Pages: 839-846
- NAID
  10031131378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790437
[Journal Article] Microbial Interaction of Periodontopathic Bacterium Porphyromonas gingivalis and HIV -Possible Causal Link of Periodontal Diseases to AIDS Progression2011
- Author(s)
  Imai K,Victriano AF,Ochiai K,Okamoto T
- Journal Title
  
  J. 0ral Biosci
  
  Volume: vol.53(3) Issue: 3 Pages: 213-220
- DOI
  10.1016/s1349-0079(11)80004-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] 感染症における微生物間相互作用-酪酸産生常在菌による潜伏感染HIV-1賦活化-2011
- Author(s)
  今井健一
- Journal Title
  
  無菌生物J Germfree Life gnotobiol
  
  Volume: 第41巻 Pages: 117-121
- NAID
  10029976312
- Data Source
  KAKENHI-PROJECT-21592664
[Journal Article] Role of histone modification on transcriptional regulation and HIV-1 gene expression: possible mechanisms of periodontal diseases in AIDS progression.2011
- Author(s)
  Imai K
- Journal Title
  
  J Oral Sci.
  
  Volume: 53 Pages: 1-13
- NAID
  130000659030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] Novel histone deacetylase inhibitor NCH-51 activates latent HIV-1 gene expression2011
- Author(s)
  Ann Florence B
- Journal Title
  
  Fed.Eur.Biochem.Soc.Lett
  
  Volume: 585 Issue: 7 Pages: 1103-1111
- DOI
  10.1016/j.febslet.2011.03.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390034, KAKENHI-PROJECT-23592714
[Journal Article] Butyric acid effects in the development of periodontitis and systemic diseases2011
- Author(s)
  Ochiai K, Imai K, Tamura M, Kurita-Ochiai T
- Journal Title
  
  J Oral Biosci
  
  Volume: 53(3) Pages: 213-220
- NAID
  10029494848
- Data Source
  KAKENHI-PROJECT-21592664
[Journal Article] Novel histone deacetylase inhibitor NCH-51 activates latent HIV-1 gene expression2011
- Author(s)
  Victoriano AF, Imai K, Togami H, Ueno T, Asamitsu K, Suzuki T, Miyata N, Ochiai K, Okamoto T
- Journal Title
  
  FEBS. L.
  
  Volume: Vol.685(7) Pages: 1103-1111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790437
[Journal Article] Functional characterization of human cyclin T1 N-terminal region for human immunodeficiency virus-1 Tat transcriptional activation2011
- Author(s)
  Asamitsu K, Hibi Y, Imai K, Victoriano AF, Kurimoto E, Kato K, Okamoto T
- Journal Title
  
  J Mol Biol.
  
  Volume: Vol.410(5) Pages: 887-895
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790437
[Journal Article] 感染症における微生物間相互作用－酪酸産生常在菌による潜伏感染HIV-1賦活化－2011
- Author(s)
  今井健一
- Journal Title
  
  無菌生物
  
  Volume: 41 Pages: 117-122
- NAID
  10029976312
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] Role of histone modification on transcriptional regulation and HIV-1 gene expression: possible mechanisms of periodontal diseases in AIDS progression2011
- Author(s)
  Imai K,Ochiai K
- Journal Title
  
  Journal of Oral Science
  
  Volume: 53 Issue: 1 Pages: 1-13
- DOI
  10.2334/josnusd.53.1
- NAID
  130000659030
- ISSN
  1343-4934, 1880-4926
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] Molecular mechanisms of HIV-1 latency and its breakdown by Periodontal diseases.2010
- Author(s)
  Imai, K, et al
- Journal Title
  
  J.Oral Biosci.
  
  Volume: 52(3) Pages: 260-267
- NAID
  10027106213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790437
[Journal Article] Involvement of histone H3 Lysine 9 (H3K9) methyl transferase G9a in the maintenance of HIV-1 latency and its reactivation by BIX01294.2010
- Author(s)
  Imai K, et al.
- Journal Title
  
  J Biol.Chem.
  
  Volume: 285(22) Pages: 16538-16545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790437
[Journal Article] Involvement of histone H3 Lysine 9(H3K9) methyl transferase G9a in the maintenance of HIV-1 latency and its reactivation by BIX012942010
- Author(s)
  Imai K, Togami H, Okamoto T
- Journal Title
  
  J Biol Chem.
  
  Volume: Vol.285(22) Pages: 16538-16545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790437
[Journal Article] Reactivation of latent HIV-1 infection by the periodontopathic bacterium Porphyromonas gingivalis involves histone modification2009
- Author(s)
  Imai, k, Ochiai, K. and T. Okamoto
- Journal Title
  
  J. Immunol Vol. 182 (6)
  
  Pages: 3688-3695
- NAID
  130004570886
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790345
[Journal Article] Reactivation of latent HIV-1 infection by the periodontopathic bacterium Porphyromonas gingivalis involves histone modification2009
- Author(s)
  Imai K, Ochiai K and Okamoto T
- Journal Title
  
  J. Immunol 182(6)
  
  Pages: 3688-3695
- NAID
  130004570886
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790345
[Journal Article] Inhibition of Human Immunodeficiency Virus Type 1 Replication by Blocking IκB Kinase with Noraristeromycin2008
- Author(s)
  Asamitsu K, Yamaguchi T, Nakata K, Hibi Y, Victoriano AF, Imai K, Onozaki K, Kitade Y, Okamoto T
- Journal Title
  
  J Biochem Vol. 144(5)
  
  Pages: 581-589
- NAID
  10024913235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790345
[Journal Article] Inhibition of Human Immunodeficiency Virus Type 1 Replicati on by Blocking I k B Kinase with Noraristeromycin2008
- Author(s)
  Asamitsu K, Yamaguchi T, Naka to K, Hibi Y, Victoriano AF, Imai K, Onozaki K, Kitade Y, Okamoto T
- Journal Title
  
  J Biochem 144(5)
  
  Pages: 581-589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790345
[Journal Article] HIV転写調節機構とその治療制御の可能性2007
- Author(s)
  今井健一,岡本尚
- Journal Title
  
  蛋白質・核酸・酵素 Vol.52(10)
  
  Pages: 1121-1127
- Data Source
  KAKENHI-PROJECT-19790345
[Journal Article] Involvement of RelA-associated inhibitor (RAI) in regulation of trophoblast differentiation via interaction with transcriptional factor Sp12007
- Author(s)
  Minekawa, R, M. Sakata, Y. Okamoto, M. Hayashi, A. Isobe, T. Takeda, T. Yamamoto, M. Koyama, M. Ohmichi, K. Tasaka, K. Imai, Okamoto. T, and Y. Murata
- Journal Title
  
  Endocrinology Vol. 148(12)
  
  Pages: 5803-5810
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790345
[Journal Article] Induction ofOGG1 gene expression by HIV-1 Tat2005
- Author(s)
  Imai K
- Journal Title
  
  J.Biol.Chem. 280・29
  
  Pages: 26701-26701
- Data Source
  KAKENHI-PROJECT-17790309
[Journal Article] Transcripional Repression of Human Immunodeficiency Virus Type 1 by AP-4.2003
- Author(s)
  Imai, K.
- Journal Title
  
  J.Bioi.Chem. 281
  
  Pages: 12495-12505
- Data Source
  KAKENHI-PROJECT-17790309
[Presentation] Porphyromonas gingivalis gingipains potentially affects MUC5AC gene expression and protein levels in respiratory epithelial cells2021
- Author(s)
  Norihisa Watanabe, Sho Yokoe, Marni E. Cueno, Shuichiro Maruoka, Yasuhiro Gon, Shuichi Sato, Kenichi Imai
- Organizer
  第25回アジア太平洋呼吸器学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10078
[Presentation] 口腔とCOVID-19との関連～口腔細菌による呼吸器疾患進展の可能性～2021
- Author(s)
  今井健一
- Organizer
  第24回日本歯科医学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K10078
[Presentation] 口腔・唾液中のSARS-CoV-2.2021
- Author(s)
  今井健一
- Organizer
  第63回歯科基礎医学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K10078
[Presentation] EBV-LMP1 Potentially Contributes to Chronic Periodontitis via Inducible IL-8 Production2021
- Author(s)
  Watanabe N, Imai K, Hasuike A, Kojima T, Kawamoto K, Karahashi Y, Sato S
- Organizer
  General Session & Exhibition of the IADR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10078
[Presentation] Proinflammatory nature of aspirated Fusobacterium nucleatum may cause pneumonia2021
- Author(s)
  Sho Yokoe, Kenichi Imai, Tsunehiro Ezawa, Takeshi Fukuda, Shuichi Sato
- Organizer
  General Session & Exhibition of the IADR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10078
[Presentation] Proinflammatory nature of aspirated periodontopathic bacteria may cause pneumonia2020
- Author(s)
  Miya C, Suzuki R, Nodomi K, Tamura M, Kamio N, Kaneko T, Tonogi M, Imai K
- Organizer
  98th General Session & Exhibition of the IADR. Washington
- Data Source
  KAKENHI-PROJECT-19K10078
[Presentation] 口腔細菌のウイルス感染症促進作用－HIV再活性化とCOVID-19に及ぼす影響を中心に―2020
- Author(s)
  今井健一
- Organizer
  第34回日本エイズ学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K10078
[Presentation] The periodontopathic bacterium Fusobacterium nucleatum induced proinflammatory cytokine production by human respiratory epithelial cells and in the lower respiratory organs in mice2020
- Author(s)
  Imai k, Watanabe N, Yokoe S, Sato S
- Organizer
  第68国際歯科研究学会日本部会［JADR］総会・学術大会
- Data Source
  KAKENHI-PROJECT-19K10078
[Presentation] 下気道の炎症性疾患と口腔との関連　　－歯周病原菌による呼吸器上皮細胞とマウス下気道からの炎症性サイトカイン誘導－.2020
- Author(s)
  今井健一
- Organizer
  第60回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K10078
[Presentation] 口腔と下気道の炎症性疾患との関連. －F. nucleatumによる呼吸器からの炎症性サイトカイン誘導2020
- Author(s)
  髙橋佑和, 今井健一, 飯沼利光
- Organizer
  第31回春期日本老年歯科医学会学術大会,
- Data Source
  KAKENHI-PROJECT-19K10078
[Presentation] 口腔フローラと健康寿命－「細菌-ウイルス-宿主相互作用」の観点から－.2019
- Author(s)
  今井健一
- Organizer
  第40回日本歯内療法学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K10078
[Presentation] EBV関連悪性リンパ腫モデルマウスの作製とヒトリンパ腫との組織レベルでの比較検討2019
- Author(s)
  小池亮, 今井健一
- Organizer
  第61回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-19K10078
[Presentation] 口腔細菌と呼吸器感染症関連微生物との相互作用 ─歯周病原細菌が肺炎とインフルエンザの発症に及ぼす影響─.2019
- Author(s)
  神尾宜昌, 田村宗明, 今井健一
- Organizer
  第93回日本感染症学会総会・学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-19K10078
[Presentation] P. gingivalis LPS誘導性炎症性サイトカイン産生とRANKL誘導性破骨細胞分化に対するアーティチョーク由来シナロピクリンの抑制効果2019
- Author(s)
  渡辺典久, 横江将, 佐藤秀一, 今井健一
- Organizer
  第61回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-19K10078
[Presentation] 口腔の特性と常在微生物叢による感染症2018
- Author(s)
  今井健一
- Organizer
  第33回日本環境感染学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K11526
[Presentation] 口腔細菌による肺炎発症機序の解明－P. gingivalisは呼吸器上皮細胞の炎症性サイトカイン産生を誘導する－2018
- Author(s)
  早田真由美，田村宗明，神尾宜昌，田中一，渡辺典久，宮千尋，植田耕一郎，今井健一
- Organizer
  第91回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-15K11430
[Presentation] EBV reactivation by refractory apical periodontitis-related bacteria2018
- Author(s)
  K. Himi, O.Takeichi, K. Hatori, K. Makino, H. Kudo, H. Tanaka, K. Imai, B. Ogiso
- Organizer
  IADR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11526
[Presentation] 口腔細菌と全身疾患との関わり2018
- Author(s)
  今井健一
- Organizer
  平成30年度日本補綴歯科学会東京支部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-16K11526
[Presentation] EBV-LMP1 induces IL-8 production via regulation of the NF-kB pathway in the human gingival epithelial cells2018
- Author(s)
  Kenichi Imai
- Organizer
  The 43rd FEBS Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11526
[Presentation] 歯周病原菌P. gingivalisはPAFRの発現と肺炎球菌の肺上皮細胞への付着を促進する2018
- Author(s)
  神尾宜昌，早田真由美，渡辺典久，納富啓子，田村宗明，今井健一
- Organizer
  第91回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-15K11430
[Presentation] 口腔衛生状態と呼吸器疾患との関連から医療連携を再考する2018
- Author(s)
  今井健一
- Organizer
  第27回日本有病者歯科医療学会総会・学術大会第38回日本歯科薬物療法学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-16K11526
[Presentation] 口腔細菌による誤嚥性肺炎発症機序の解明２：歯周病原菌は呼吸器上皮細胞の炎症性サイトカイン産生を誘導する2017
- Author(s)
  今井健一，早田真由美，渡辺典久，神尾宜昌，田村宗明，田中一，植田耕一郎
- Organizer
  第23回日本摂食嚥下リハビリテーション学会学術大会
- Data Source
  KAKENHI-PROJECT-15K11430
[Presentation] 口腔細菌による誤嚥性肺炎発症メカニズムの解明;歯周病原菌は種々の呼吸器系上皮細胞からの炎症性サイトカイン産生を誘導する2017
- Author(s)
  渡辺典久, 早田真由美, 田村宗明, 神尾宜昌, 田中一, 佐藤秀一, 今井健一
- Organizer
  日本歯周病学会60周年記念京都大会
- Data Source
  KAKENHI-PROJECT-16K11526
[Presentation] 口腔細菌による誤嚥性肺炎発症メカニズムの解明－歯周病原菌は種々の呼吸器系上皮細胞からの炎症性サイトカイン産生を誘導する－2017
- Author(s)
  渡辺典久，早田真由美，田村宗明，神尾宜昌，田中一，佐藤秀一，今井健一
- Organizer
  日本歯周病学会60周年記念京都大会
- Data Source
  KAKENHI-PROJECT-15K11430
[Presentation] 歯周病の発生と進展におけるEBV関与の可能性－EBVのLMP1はNF-κBを活性化し歯肉上皮細胞からの炎症性サイトカインを誘導する－2017
- Author(s)
  今井健一, 渡邊典久, 佐藤秀一, 小方頼昌
- Organizer
  第60回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11526
[Presentation] 口腔細菌による誤嚥性肺炎発症機序の解明2: 歯周病原菌は呼吸器上皮細胞の炎症性サイトカイン産生を誘導する.2017
- Author(s)
  今井健一, 早田真由美, 渡辺典久, 神尾宜昌, 田村宗明, 田中一, 植田耕一郎
- Organizer
  第23回日本摂食嚥下リハビリテーション学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11526
[Presentation] EBV-LMP1 promotes production of inflammatory cytokines through NF-kB signaling in gingival epithelial cells: its potentioal implication in periodontitis progression.2017
- Author(s)
  今井健一
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K11526
[Presentation] 歯周病原菌と肺炎発症との関連：Porphyromonas gingivalisは気道上皮細胞において肺炎球菌受容体PAFRの発現を増強する2017
- Author(s)
  神尾宜昌, 早田真由美, 渡辺典久, 田村宗明, 今井健一
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-15K11430
[Presentation] EBVによる歯周病の発症・進展機序の解明 - EBVのLMP1はNF-κBを活性化し歯肉上皮細胞からのIL-8産生を誘導する-2017
- Author(s)
  渡辺典久, 小池亮, 早田真由美, 金子忠良, 佐藤秀一, 今井健一
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11526
[Presentation] 口腔細菌による誤嚥性肺炎発症メカニズムの解明（１）P. gingivalisは肺炎球菌レセプターPAFRの発現を誘導する2017
- Author(s)
  早田真由美，神尾宜昌，田村宗明，渡辺典久，植田耕一郎，今井健一
- Organizer
  第23回日本摂食嚥下リハビリテーション学会学術大会
- Data Source
  KAKENHI-PROJECT-15K11430
[Presentation] 慢性歯周炎の発症と進行へのエプスタインバーウイルス(EBV)と　P. gingivalisの関与2016
- Author(s)
  加藤彩子　今井健一　神尾宜昌　岡林堅　小方頼昌
- Organizer
  第２３回　日本歯科医学会総会
- Place of Presentation
  福岡国際会議場(福岡県福岡市）
- Year and Date
  2016-10-21
- Data Source
  KAKENHI-PROJECT-16K11526
[Presentation] 口腔細菌のウィルス感染症促進作用ーEBVおよびインフルエンザ感染に及ぼす影響－2016
- Author(s)
  今井健一, 神尾宜昌
- Organizer
  第19回日本臨床腸内微生物学会総会学術大会
- Place of Presentation
  杏林大学（東京都三鷹市）
- Year and Date
  2016-08-27
- Invited
- Data Source
  KAKENHI-PROJECT-16K11526
[Presentation] Porphyromonas gingivalisがインフルエンザウイルス感染に及ぼす影響2016
- Author(s)
  神尾宜昌，今井健一
- Organizer
  第65回日本口腔衛生学会・総会
- Place of Presentation
  東京医科歯科大学（東京都・文京区）
- Year and Date
  2016-05-27
- Data Source
  KAKENHI-PROJECT-15K11430
[Presentation] ィンプラント周囲滲出液からのエプスタインバーウイルス(EBV)DNAの検出2016
- Author(s)
  小方頼昌　今井健一　神尾宜昌　高井英樹　加藤　彩子
- Organizer
  第２３回　日本歯科医学会総会
- Place of Presentation
  福岡国際会議場(福岡県福岡市）
- Year and Date
  2016-10-21
- Data Source
  KAKENHI-PROJECT-16K11526
[Presentation] Streptococcus pneumoniae 培養上清はインフルエンザウイルス感染拡大に働く2016
- Author(s)
  神尾宜昌, 落合邦康，今井健一
- Organizer
  第58回歯科基礎医学会学術大会
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌市）
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-15K11430
[Presentation] Quantitative Analysis of EBV DNA and P. gingivalis Associated with Peri-implantitis2016
- Author(s)
  Ａyako Kato, Kenichi Imai, Kuniyasu Ochiai, and Yorimasa Ogata
- Organizer
  IADR General Session
- Place of Presentation
  Seoul(Korea)
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11526
[Presentation] 肺炎球菌培養上清はインフルエンザウイルスの感染拡大に働く2016
- Author(s)
  神尾宜昌, 今井健一，落合邦康
- Organizer
  第89回日本細菌学会総会
- Place of Presentation
  大阪国際交流センター（大阪府・大阪市）
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-15K11430
[Presentation] ジンジパインがインフルエンザウイルス感染に及ぼす影響2015
- Author(s)
  神尾宜昌, 今井健一, 中山浩次，落合邦康
- Organizer
  第57回歯科基礎医学会学術大会
- Place of Presentation
  朱鷺メッセ（新潟県・新潟市）
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15K11430
[Presentation] 歯周病原細菌Porphyromonas gingivalis の産生するジンジパインがインフルエンザウイルス感染に及ぼす影響2015
- Author(s)
  Noriaki Kamio, Kenichi Imai, Kazufumi Shimizu, Kuniyasu Ochiai
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場（福岡県・福岡市）
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K11430
[Presentation] 日本人慢性歯周炎患者でのEBウイルスと歯周病原菌の検出.2014
- Author(s)
  加藤彩子, 今井健一, 落合邦康, 小方頼昌
- Organizer
  第57回秋季日本歯周病学会学術大会
- Place of Presentation
  神戸国際展示場(兵庫県神戸市）
- Year and Date
  2014-10-19
- Data Source
  KAKENHI-PROJECT-24592843
[Presentation] 口腔細菌はインフルエンザウィルス感染を促進する2014
- Author(s)
  神尾宜目、今井健一、田村宗明、Marni Cueno、粛藤夕子、落合邦康
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  タワーホール船堀、東京
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] 口腔細菌のウィルス感染症促進作用　－ＥＢＶおよびインフルエンザ感染に及ぼす影響－2014
- Author(s)
  今井健一、神尾宜昌、落合邦康
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  タワーホール船堀，東京
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] 口腔細菌のウイルス感染症促進作用ーEBVおよびインフルエンザ感染に及ぼす影響ー2014
- Author(s)
  今井健一、神尾宜目、落合邦康
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  タワーホール船堀、東京
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] 口腔細菌はインフルエンザウィルス感染を促進する2014
- Author(s)
  神尾宜昌、今井健一、田村宗明、Ｍａｒｎｉ　Ｃｕｅｎｏ、齋藤夕子、落合邦康
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  タワーホール船堀，東京
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] Ｓｔｒｕｃｔｕｒａｌ　ｓｉｇｎｉｆｉｃａｎｃｅ　ｏｆ　ｔｈｅ　ｂｅｔａ1ｋ396 residue found in the Porphyromonas gingivalis sialidase2014
- Author(s)
  齋藤夕子、Ｍａｒｎｉ　Ｃｕｅｎｏ、神尾宜昌、今井健一、田村宗明、落合邦康
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  タワーホール船堀，東京
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] P. gingivalis EBV相互作用による潜伏感染EBVの再活性化と病態への関与.2013
- Author(s)
  今井健一他
- Organizer
  第86回日本細菌学会総会
- Place of Presentation
  幕張メッセ (千葉)
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] 歯周病原細菌代謝産物・酪酸の歯周組織に及ぼす影響と潜伏感染ウイルスの再活性化2013
- Author(s)
  落合邦康、今井健一、落合智子
- Organizer
  第86回日本細菌学会総会
- Place of Presentation
  幕張メッセ国際会議場、千葉
- Year and Date
  2013-03-20
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] P.gingivalis-EBV相互作用による潜伏感染EBVの再活性化と病態への関与2013
- Author(s)
  今井健一他
- Organizer
  第86回日本細菌学会総会
- Place of Presentation
  幕張メッセ (千葉)
- Data Source
  KAKENHI-PROJECT-24592843
[Presentation] 歯周病原細菌による潜伏感染EBVの再活性化と病態への関与2012
- Author(s)
  今井健一
- Organizer
  第45回日本無菌生物ノートバイオロジー学会総会
- Place of Presentation
  グランデール岐山,岐阜
- Year and Date
  2012-01-13
- Data Source
  KAKENHI-PROJECT-22790437
[Presentation] HIV感染症における微生物間相互作用-酪酸産生常在菌による潜伏感染HIV-1の再活性化-2012
- Author(s)
  今井健一
- Organizer
  第85回日本細菌学会総
- Place of Presentation
  長崎ブリックホール,長崎
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-22790437
[Presentation] EBV-歯周病原細菌間相互作用による潜伏感染EBVの再活性化と病態への関与2012
- Author(s)
  今井健一、落合邦康
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪国際会議場、大阪
- Year and Date
  2012-11-14
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] Reactivation of latent HIV-1 infection by butyric acid-producing bacteria involves histone modification2012
- Author(s)
  今井健一
- Organizer
  International Union of Microbiological Societies 2011 & Congress concurrently held with the 15th International Congress of Virology held at Sapporo
- Place of Presentation
  Hokkaido, Japan
- Year and Date
  2012-09-14
- Data Source
  KAKENHI-PROJECT-22790437
[Presentation] HIV感染症における微生物間相互作用-酪酸産生常在菌による潜伏感染HIV-1の再活性化-2012
- Author(s)
  今井健一
- Organizer
  第85回細菌学会総会
- Place of Presentation
  長崎ブリックホール(長崎県)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21592664
[Presentation] Influenza A H1N1 Pathogenesis And Transmissibility Are Structurally Correlated To The Salt Bridge Between The HA1 110-helix And HA2 B-loop2012
- Author(s)
  Cueno,M.E. K. Imai,and K. 0chiai
- Organizer
  Second isirv AVG conference
- Place of Presentation
  Melia Hotel,Vietnam
- Year and Date
  2012-10-30
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] Candida albicansに対する抗菌ジェルの病原性抑制効果と臨床応用2012
- Author(s)
  田村宗明、齋藤秀雄、今井健一、落合邦康
- Organizer
  第85回細菌学会総会
- Place of Presentation
  長崎ブリックホール・長崎県
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-21592664
[Presentation] HIV感染症における微生物間相互作用-酪酸産生常在菌による潜伏感染HIV-1の再活性化-2012
- Author(s)
  今井健一, 他
- Organizer
  第85回日本細菌学会総会
- Place of Presentation
  長崎ブリックホール,(長崎県)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-22790437
[Presentation] 歯周病原細菌による潜伏感染EBVの再活性化と病態への関与2012
- Author(s)
  今井健一, 他
- Organizer
  第45回日本無菌生物ノートバイオロジー学会総会
- Place of Presentation
  グランデール岐山,(岐阜県)
- Year and Date
  2012-01-13
- Data Source
  KAKENHI-PROJECT-22790437
[Presentation] ウイルス感染症における口腔細菌学の影響.歯周病原菌による潜伏感染EBVの再活性化機構2011
- Author(s)
  今井健一
- Organizer
  第53回歯科基礎医学会学術大会ならびに総会
- Place of Presentation
  長良川国際会議場,岐阜
- Year and Date
  2011-09-30
- Data Source
  KAKENHI-PROJECT-22790437
[Presentation] ウイルス感染症における口腔細菌学の影響-歯周病原菌による潜伏感染EBVの再活性化機構-2011
- Author(s)
  今井健一, 他
- Organizer
  第53回歯科基礎医学会学術大会
- Place of Presentation
  長良川国際会議場,(岐阜県)(招待講演)
- Year and Date
  2011-09-30
- Data Source
  KAKENHI-PROJECT-22790437
[Presentation] Reactivation of latent HIV-1 infection by butyric acid-producing bacteria involves histone modification2011
- Author(s)
  今井健一, 他
- Organizer
  International Union of Microbiological Societies 2011 & Congress concurrently held with the 15th International Congress of Virology held at Sapporo
- Place of Presentation
  Hokkaido, Japan
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-22790437
[Presentation] Reactivation of latent HIV-1 infection by butyric acid-producing bacteria involves histone modification2011
- Author(s)
  Imai K
- Organizer
  IUMS 2011
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Year and Date
  2011-09-13
- Data Source
  KAKENHI-PROJECT-21592664
[Presentation] 感染症における微生物間相互作用-酪酸産生常在菌の潜伏感染HIV-1賦活化におよぼす影響-2011
- Author(s)
  今井健一, 田村宗明, ら
- Organizer
  第44回日本無菌生物ノートバイオロジー学会
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2011-01-14
- Data Source
  KAKENHI-PROJECT-21592664
[Presentation] Reactivation of latent HIV-1 infection by butyric acid-producing bacteria involves histone modification2011
- Author(s)
  K Imai,M Tamura,K Yamada,T 0kamoto,K 0chiai
- Organizer
  国際微生物学連合
- Place of Presentation
  札幌コンベンションセンター、北海道
- Year and Date
  2011-09-13
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] BIX01294はRAW264.7細胞のRANKL誘導破骨細胞分化を抑制する2011
- Author(s)
  津田啓方、今井健一、落合邦康、鈴木直人
- Organizer
  第53回歯科基礎医学会学術大会ならびに総会
- Place of Presentation
  長良川国際会議場、岐阜
- Year and Date
  2011-10-02
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] Reactivation of latent HIV-1 by a wide variety of butyric acid-producing bacteria2011
- Author(s)
  今井健一
- Organizer
  The joint meeting the 17th international symposium on gnotobiology and the 34th congress of the society for microbial Ecology and disease
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2011-11-22
- Data Source
  KAKENHI-PROJECT-22790437
[Presentation] Effects of butyric acid-producing bacteria on reactivation of latent HIV-12010
- Author(s)
  Imai K, Tamura M, et al
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  神戸ポートピアホテル(兵庫県)
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PROJECT-21592664
[Presentation] Reactivation of latent HIV-1 infection by butyric acid-producing bacteria involves hismodification2010
- Author(s)
  Imai, K, et al
- Organizer
  5th German-Japanese HIV-Symposium
- Place of Presentation
  Keio Univ., Tokyo
- Year and Date
  2010-05-10
- Data Source
  KAKENHI-PROJECT-22790437
[Presentation] 酪酸産生菌による潜伏感染HIV-1の再活性化2010
- Author(s)
  今井健一, 他
- Organizer
  第52回歯科基礎医学会学術大会ならびに総会
- Place of Presentation
  ワーホール船堀(東京)
- Year and Date
  2010-09-21
- Data Source
  KAKENHI-PROJECT-22790437
[Presentation] 酪酸産生菌による潜伏感染HIV-1の再活性化2010
- Author(s)
  今井健一, 田村宗明, ら
- Organizer
  第52回歯科基礎医学会学術大会ならびに総会
- Place of Presentation
  タワーホール船堀(東京都)
- Year and Date
  2010-09-21
- Data Source
  KAKENHI-PROJECT-21592664
[Presentation] Effects of butyric acid-producing bacteria on reactivation of latent HIV-12010
- Author(s)
  Imai, K, et al
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  神戸国際展示場
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PROJECT-22790437
[Presentation] 歯周病とHIV-歯周病原細菌によるエピジェネティック制御を介する潜伏HIVの賦活化-2010
- Author(s)
  今井健一, 田村宗明, ら
- Organizer
  平成22年度日本大学学部連携研究推進シンポジウム
- Place of Presentation
  日大会館(東京都)
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21592664
[Presentation] 感染症における微生物間相互作用-酪酸産生常在菌による潜伏感染HIV-1の再活性化-2010
- Author(s)
  今井健一, 他
- Organizer
  第93回日本細菌学会関東支部総会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2010-10-22
- Data Source
  KAKENHI-PROJECT-22790437
[Presentation] 腸内細菌代謝産物による潜伏感染HIV-1の再活性化2010
- Author(s)
  今井健一, 田村宗明, ら
- Organizer
  第14回腸内細菌学会
- Place of Presentation
  京都大学(京都府)
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-21592664
[Presentation] 感染症における微生物間相互作用-酪酸産生常在菌による潜伏感染HIV-1の再活性化-2010
- Author(s)
  今井健一, 田村宗明, ら
- Organizer
  第93回日本細菌学会関東支部総会
- Place of Presentation
  京王プラザホテル(東京都)
- Year and Date
  2010-10-21
- Data Source
  KAKENHI-PROJECT-21592664
[Presentation] HIV感染症における微生物間相互作用-酪酸産生常在菌による潜伏感染HIV-1の性化-2010
- Author(s)
  今井健一, 他
- Organizer
  第58回日本ウイルス学会学術集会・総会
- Place of Presentation
  徳島県郷土文化会館
- Year and Date
  2010-10-09
- Data Source
  KAKENHI-PROJECT-22790437
[Presentation] Microbe interactions leading to AIDS development : Interaction between HIV and Porphyromonas gingivalis, a causative agent of periodontitis2009
- Author(s)
  T. Okamoto and K. Imai
- Organizer
  4TH GERMAN-JAPANESE HIV-SYMPOSIUM
- Place of Presentation
  Horsaalzentrum, St. Josef Hospital, Bochum, Germany
- Data Source
  KAKENHI-PROJECT-19790345
[Presentation] Involvement of histone 3 lysine 9 (H3K9) dimethyl transferase G9a in the maintenance of HIV-1 latency and its reactivation by BIX012942009
- Author(s)
  Imai, K., Togami, H. and T. Okamoto
- Organizer
  4TH GERMAN-JAPANESE HIV-SYMPOSIUM
- Place of Presentation
  Horsaalzentrum, St. Josef Hospital, Bochum, Germany
- Data Source
  KAKENHI-PROJECT-19790345
[Presentation] Involvement of histone 3 lysine 9 (H3K9) dimethyl transferase G9a in the maintenance of HIV-1 latency and its reactivation by BIX012942009
- Author(s)
  Imai K, Togami H and Okamoto T
- Organizer
  4TH GERMAN-JAPANESE HIV-SYMPOSI UM
- Place of Presentation
  Horsaalzentrum, St. Josef Hospital, Bochum, Germany
- Data Source
  KAKENHI-PROJECT-19790345
[Presentation] Microbe interactions leading to AIDS development: Interaction between HIV and Porphyromonas gingivalis, a causative agent of periodontitis2009
- Author(s)
  Okamoto T and Imai K
- Organizer
  4TH GERMAN-JAPANESE HIV-SYMPOSIUM
- Place of Presentation
  Horsaalzentrum, St. Josef Hospital, Bochum, Germany
- Data Source
  KAKENHI-PROJECT-19790345
[Presentation] 歯周病によるAIDS進展の可能性(1)-P. gingivalisによるヒストン修飾を介する潜伏HIVの賦活化-2009
- Author(s)
  今井健一、落合邦康、岡本尚
- Organizer
  第82回日本細菌学会総会
- Place of Presentation
  名古屋国際会議場(名古屋市)
- Data Source
  KAKENHI-PROJECT-19790345
[Presentation] 歯周病によるAIDS進展の可能性(2)-各種歯周病原菌の潜伏感染HIV活性化に及ぼす影響-2009
- Author(s)
  落合邦康、今井健一、岡本尚
- Organizer
  第82回日本細菌学会総会
- Place of Presentation
  名古屋国際会議場(名古屋市)
- Data Source
  KAKENHI-PROJECT-19790345
[Presentation] Reactivation of latent HIV-1 infection by the periodontopatic bacterium Porphyromonas gingivalis involves histone modification2008
- Author(s)
  Okamoto T, Imai K, and Ochiai K
- Organizer
  The 21^<st> Meeting Japan-USA Cooperative Medical Program /AIDS Panel
- Place of Presentation
  兵庫県立淡路夢舞台国際会議場・国立感染症研究所
- Data Source
  KAKENHI-PROJECT-19790345
[Presentation] 歯周病とエイズの密接な関係-P. gingivalisの産生する酪酸がクロマチン修飾を介してHIV-1転写を活性化する2008
- Author(s)
  今井健一、落合邦康、岡本尚
- Organizer
  第51回日本歯周病学会秋季学術大会
- Place of Presentation
  四日市市文化会館(四日市市)
- Data Source
  KAKENHI-PROJECT-19790345
[Presentation] Reactivation of latent HIV-1 infection by the periodontopatic bacterium Porphyromonas gingivalis involves histone modification2008
- Author(s)
  T. Okamoto, K. Imai, K. Ochiai
- Organizer
  The 21st. Meeting Japan-USA Cooperative Medical Program /AIDS Panel
- Place of Presentation
  Awaji and Tokyo(兵庫県立淡路夢舞台国際会議場・国立感染症研究所), Japan
- Data Source
  KAKENHI-PROJECT-19790345
[Presentation] クロマチンリモデリングを介するグラム陰性嫌気性菌感染症による潜伏HIVの賦活化2008
- Author(s)
  今井健一、岡本尚
- Organizer
  第22回日本エイズ学会学術集会・総会
- Place of Presentation
  大阪国際交流センター(大阪市)
- Data Source
  KAKENHI-PROJECT-19790345
[Presentation] グラム陰性嫌気性菌感染症によるクロマチン修飾を介する潜伏HIVの賦活化2008
- Author(s)
  今井健一、岡本尚
- Organizer
  第22回日本エイズ学会学術集会・総会
- Place of Presentation
  大阪国際交流センター(大阪市)
- Data Source
  KAKENHI-PROJECT-19790345
[Presentation] クロマチンリモデリングを介するグラム陰性嫌気性菌感染症による潜伏HIVの賦活化2008
- Author(s)
  今井健一、岡本尚
- Organizer
  第31回日本分子生物学会、第81回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(神戸市)
- Data Source
  KAKENHI-PROJECT-19790345
[Presentation] グラム陰性嫌気性菌感染症によるHIVの転写レベルでの賦活化2008
- Author(s)
  今井健一、岡本尚
- Organizer
  第56回日本ウイルス学会学術集会・総会
- Place of Presentation
  岡山コンベンションセンター(岡山市)
- Data Source
  KAKENHI-PROJECT-19790345
[Presentation] 歯周病によるHIVの転写レベルでの賦活化-P. gingivalisの産生する酪酸がクロマチン修飾を介してHIV-1転写を活性化する-2008
- Author(s)
  今井健一、落合邦康、岡本尚
- Organizer
  第50回歯科基礎医学会学術大会
- Place of Presentation
  TOC有明コンベンションホール(東京)
- Data Source
  KAKENHI-PROJECT-19790345
[Presentation] 歯周病原細菌の潜伏感染HIV-1賦活化におよぼす影響2008
- Author(s)
  落合邦康、今井健一、岡本尚
- Organizer
  第51回日本歯周病学会秋季学術大会
- Place of Presentation
  四日市市文化会館(四日市市)
- Data Source
  KAKENHI-PROJECT-19790345
[Presentation] 歯周病とエイズの密接な関係-P. gingivalisの産生する酪酸がクロマチン修飾を介してHIV-1転写を活性化する2008
- Author(s)
  今井健一、落合邦康、岡本尚
- Organizer
  第51回秋季日本歯周病学会学術大会
- Place of Presentation
  四日市市文化会館(四日市市)
- Data Source
  KAKENHI-PROJECT-19790345
[Presentation] 潜伏感染HIV-1に対する種々の歯周病原細菌の賦活化作用2008
- Author(s)
  落合邦康、今井健一、岡本尚
- Organizer
  第50回歯科基礎医学会学術大会
- Place of Presentation
  TOC有明コンベンションホール(東京)
- Data Source
  KAKENHI-PROJECT-19790345
[Presentation] 歯周病による潜伏感染HIV-1賦活化の可能性2008
- Author(s)
  落合邦康、今井健一、岡本尚
- Organizer
  第91回日本細菌学会関東支部総会
- Place of Presentation
  生命の森リゾート(千葉)
- Data Source
  KAKENHI-PROJECT-19790345
[Presentation] Positive involvement of Cyclin T1 in the protein stability of Tat2007
- Author(s)
  今井健一、朝光かおり、岡本尚
- Organizer
  第21回日本エイズ学会学術集会・総会
- Place of Presentation
  広島国際会議場(広島市)
- Data Source
  KAKENHI-PROJECT-19790345
[Presentation] Cychn T1はHIV Tatの安定性に関与する2007
- Author(s)
  今井健一、朝光かおり、岡本尚
- Organizer
  第21回日本エイズ学会学術集会.総会
- Place of Presentation
  広島国際会議場
- Data Source
  KAKENHI-PROJECT-19790345
[Presentation] Butyric acid-induced HEME increase is correlated with SIRT1 decrease in gingival tissues．
- Author(s)
  Marni E. Cueno, Kenichi Imai, Noriko Matsukawa, Takamitsu Tsukahara and Kuniyasu Ochiai
- Organizer
  The 20th IAGG world congressof Gerontology and Geriatrics
- Place of Presentation
  Seoul Coex Convention Center（韓国）
- Data Source
  KAKENHI-PROJECT-24592843
[Presentation] H3K2メチル化酵素Suv39h1による潜伏感染EBVの維持とSuv39h1阻害剤カエトシンによるその破綻機構の解析
- Author(s)
  今井健一, 落合邦康
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市）
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24592843
[Presentation] EBV潜伏感染維持と破綻機構の解明と炎症性疾患への関与.
- Author(s)
  齋藤夕子, 今井健一, 落合邦康
- Organizer
  第56回歯科基礎医学会学術大会・総会
- Place of Presentation
  福岡国際会議場(福岡県福岡市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24592843
[Presentation] HIV 唾液検査の科学的検証とHIV 検査相談機会の拡大に関する取り組み.
- Author(s)
  今井健一, 落合邦康
- Organizer
  第55回歯科基礎医学会学術大会
- Place of Presentation
  岡山コンベンションセンター（岡山）
- Data Source
  KAKENHI-PROJECT-24592843
[Presentation] Microbial interaction of periodontopathic bacteria and Epstein Barr virus in periodontal diseases -Porphyromonas gingivalis induces the EBV lytic switch transactivator ZEBRA by histone modification-.
- Author(s)
  今井健一他
- Organizer
  First International Conference on Porphyromonas gingivalis and Related Bacterial Species.
- Place of Presentation
  長崎大学 (長崎)
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] EBV-歯周病原細菌間相互作用による潜伏感染EBVの再活性化と病態への関与.
- Author(s)
  今井健一他
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪国際会議場 (大阪)
- Data Source
  KAKENHI-PROJECT-24592843
[Presentation] 口腔細菌のウイルス感染症促進作用―EBVおよびインフルエンザ感染に及ぼす影響―
- Author(s)
  今井健一, 神尾宜昌, 落合邦康
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  タワーホール船堀（東京）
- Data Source
  KAKENHI-PROJECT-24592843
[Presentation] 歯周病原細菌による潜伏感感染EBVの再活性化と病態への関与.
- Author(s)
  今井健一他
- Organizer
  第55回日本歯周病学会秋季学術大会
- Place of Presentation
  つくば国際会議場 (茨城)
- Data Source
  KAKENHI-PROJECT-24592843
[Presentation] ウィルス感染症における口腔細菌学の影響　－歯周病原菌による潜伏感染ＥＢＶの再活性化機構－
- Author(s)
  今井健一
- Organizer
  第53回歯科基礎医学会学術大会・総会
- Place of Presentation
  長良川国際会議場（岐阜県）
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] Role of Sp1 in butyric acid-induced HIV-1 gene expression.
- Author(s)
  Imai K, Ochiai K
- Organizer
  FEBS EMBO 2014 Conference
- Place of Presentation
  Paris, France
- Year and Date
  2014-08-30 – 2014-09-04
- Data Source
  KAKENHI-PROJECT-24592843
[Presentation] Reactivation of latent HIV-1 infection by butyric acid-producing bacteria involves histone modification.
- Author(s)
  Imai K.
- Organizer
  国際微生物学連合
- Place of Presentation
  札幌コンベンションセンター（北海道）
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] 細菌-ウイルス間相互作用による歯周病発症メカニズムの可能性.
- Author(s)
  今井健一他
- Organizer
  第54回歯科基礎医学会学術大会ならびに総会
- Place of Presentation
  奥羽大学, (福島)
- Data Source
  KAKENHI-PROJECT-24592843
[Presentation] Microbial interaction of periodontopathic bacteria and Epstein–Barr virus in periodontal diseases -Porphyromonas gingivalis induces the EBV lytic switch transactivator ZEBRA by histone modification-.
- Author(s)
  今井健一他
- Organizer
  First International Conference on Porphyromonas gingivalis and Related Bacterial Species.
- Place of Presentation
  長崎大学 (長崎)
- Data Source
  KAKENHI-PROJECT-24592843
[Presentation] EBV-歯周病原細菌間相互作用による潜伏感染EBVの再活性化と病態への関与.
- Author(s)
  今井健一他
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪国際会議場 (大阪)
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] Butyric acid-retention in the rat gingival tissue induces whole blood oxidative stress and apoptosis: A possible link to systemic diseases.
- Author(s)
  Marni E. Cueno, Kenichi Imai, Muneaki Tamura, Kuniyasu Ochiai
- Organizer
  第13回日本ミトコンドリア学会
- Place of Presentation
  六本木アカデミーヒルズ（東京）
- Data Source
  KAKENHI-PROJECT-24592843
[Presentation] 酪酸産生菌による潜伏感染ウィルス再活性化．
- Author(s)
  今井健一, 落合邦康
- Organizer
  第17回日本腸内細菌学会
- Place of Presentation
  北里大学コンベンションホール（東京）
- Data Source
  KAKENHI-PROJECT-24592843
[Presentation] EBVの歯周病発症と進展への関与
- Author(s)
  今井健一, 小方頼昌, 加藤彩子, 落合邦康
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸国際会議場（兵庫）
- Data Source
  KAKENHI-PROJECT-24592843
[Presentation] 歯根肉芽腫におけるEpstein-Barr virusの検出.
- Author(s)
  牧野公亮, 武市　収, 羽鳥啓介, 勝呂尚, 平亜希子, 今井健一, 落合邦康, 小木曾文内
- Organizer
  日本歯科保存学会2014年度春季学術大会
- Place of Presentation
  滋賀県立芸術劇場（滋賀県大津市）
- Year and Date
  2014-06-19 – 2014-06-20
- Data Source
  KAKENHI-PROJECT-24592843

1. TAMURA Muneaki (30227293)

# of Collaborated Projects: 3 results

# of Collaborated Products: 22 results
2. OCHIAI Kuniyasu (50095444)

# of Collaborated Projects: 2 results

# of Collaborated Products: 21 results
3. KAMIO Noriaki (60546472)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
4. OKAMOTO Takashi (40146600)

# of Collaborated Projects: 1 results

# of Collaborated Products: 26 results
5. YAMADA Kiyoshi (30313076)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SENPUKU Hidenobu (20250186)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TSUDA Hiromasa (60325470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. SHIMIZU Kazufumi (50004677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. Hideo Yonezawa (60453528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 戸原玄 (00396954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 丸岡秀一郎 (80599358)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 岡崎章悟 (20784044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 蓮池聡 (60636413)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. UEDA Kouichirou

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. CUENO Marni

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. 小方頼昌

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 井上裕子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 斎藤一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 武市収

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 吉田彩佳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

IMAI Kenichi 今井 健一

Research Projects

Research Products

Co-Researchers

歯周病発症機序のパラダイムシフトへの挑戦 ーヒト化マウスでのウイルス関与の立証 ーPrincipal Investigator

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Strategic approach towards etiological elucidation and novel therapeutic and prophylactic development of lower respiratory diseases due to aspiration of periodontopathic bacteriaPrincipal Investigator

Principal Investigator

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Analysis of the possibility that colonization of bacteriocin-producing bacteria in the oral cavity may cause intestinal microbiota dysbiosis

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A strategic approach to elucidate the etiology of EBV-induced periodontitis and to develop novel therapiesPrincipal Investigator

Principal Investigator

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Review Section

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Strategic approach towards etiological elucidation and novel therapy development of periodontitis attributed to EBVPrincipal Investigator

Principal Investigator

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Study on the effects of oral bacteria in influenza virus infection

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Etiological elucidation of periodontal disease attributed to EBVPrincipal Investigator

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Effects of butyric acid producing bacteria on epigenetic gene regulation and systemic diseases

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Elucidation of molecular mechanisms HIV viral latency and its reactivation involving epigenetic regulationPrincipal Investigator

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Possibility of the oral microorganism control in the elderly by a gel-entrapped catechin

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Role of transcriptional factor AP-4 in the maintenance of HIV-1 latencyPrincipal Investigator

Principal Investigator

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転写因子AP-4によるHIV遺伝子発現抑制機構の解明Principal Investigator

Principal Investigator

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[Book] 口腔微生物学 感染と免疫2021

Author(s)

Total Pages

Publisher

IMAI Kenichi 今井健一

歯周病発症機序のパラダイムシフトへの挑戦ーヒト化マウスでのウイルス関与の立証ーPrincipal Investigator

[Book] 口腔微生物学　感染と免疫2021

[Book] 口腔微生物学－感染と免疫－　第6版2018

[Book] 化学療法の領域　「口腔内細菌とウイルス感染症　-歯周病原菌によるエピジェネティック制御を介する潜伏HIVの再活性化機構-」2011

[Journal Article] 口腔と全身疾患研究の最前線　はじめに2021