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Kubota Tetsuya  窪田 哲也

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KUBOTA Tetsuya  窪田 哲也

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Researcher Number 60385698
Affiliation (Current) 2025: 公益財団法人朝日生命成人病研究所, その他部局等, 教授(移行)
2025: 東邦大学, 医学部, 研究員
Affiliation (based on the past Project Information) *help 2019 – 2025: 公益財団法人朝日生命成人病研究所, その他部局等, 教授(移行)
2018: 国立研究開発法人理化学研究所, 生命医科学研究センター, 上級研究員
2017: 国立研究開発法人理化学研究所, 統合生命医科学研究センター, 上級研究員
2015: 国立研究開発法人理化学研究所, 統合生命医科学研究センター, 上級研究員
2015: 理化学研究所, 統合生命医科学研究センター代謝恒常性研究チーム, 上級研究員 … More
2013 – 2014: 独立行政法人理化学研究所, 統合生命医科学研究センター, 上級研究員
2013: 独立行政法人国立健康・栄養研究所
2013: 独立行政法人理化学研究所, その他部局等, 研究員
2012: 独立行政法人国立健康・栄養研究所, その他部局等, 室長
2011: 独立行政法人国立健康・栄養研究所, その他部局等, 研究員
2011: 独立行政法人国立健康・栄養研究所, 臨床栄養研究部・栄養療法研究室, 室長
2011: 独立行政法人国立健康・栄養研究所, 臨床栄養研究部栄養療法研究室, 室長
2009 – 2010: National Institute of Health and Nutrition, 臨床栄養プログラム栄養療法プロジェクト, プロジェクトリーダー
2006: National Institute of Health and Nutrition, Clinical Nutrition Program, Postdoctoral Researcher, 臨床栄養プログラム, 任期付研究員 Less
Review Section/Research Field
Principal Investigator
Basic Section 54040:Metabolism and endocrinology-related / Metabolomics
Except Principal Investigator
Basic Section 54040:Metabolism and endocrinology-related / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Radiation science / Metabolomics / General internal medicine (including Psychosomatic medicine)
Keywords
Principal Investigator
インスリン抵抗性 / インスリンシグナル / 血管内皮細胞 / 動脈硬化 / 糖尿病 / 肥満 / bone marrow cells, macrophage / endothelial cell-specific IRS-2 knockout mice / insulin signaling / atherosclerosis … More / insulin resistance / 骨髄細胞・マクロファージ / 血管内皮細胞特異的IRS-2欠損マウス / インスリン受容体基質2 / 肝臓 / 遺伝子 / シグナル伝達 … More
Except Principal Investigator
マクロファージ / 肝臓 / インスリン抵抗性 / インスリン作用 / 糖尿病 / アディポネクチン / 分子イメージング / 核医学 / アイソトープ / イメージング / 心臓サルコイドーシス / 画像診断 / ソマトスタチン受容体 / 慢性炎症 / 心臓画像診断 / ソマトスタチンサブタイプ2受容体 / 炎症イメージング / 心臓イメージング / ソマトスタチン受容体イメージング / 心臓マクロファージ / 心臓炎症イメージング / 肝臓のインスリン抵抗性 / インスリン受容体基質-2 / 糖産生 / 摂食調節 / インスリン受容体基質2 / 心サルコイドーシス / マウスモデル / 常在菌 / アクネ菌 / 繊維化 / 心筋炎 / 心筋症 / サルコイドーシス Less
  • Research Projects

    (11 results)
  • Research Products

    (170 results)
  • Co-Researchers

    (18 People)
  •  選択的インスリン抵抗性と慢性炎症を介した動脈硬化発症メカニズムの解明Principal Investigator

    • Principal Investigator
      窪田 哲也
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      The Institute for Adult Diseases Asahi Life Foundation
  •  インスリンシグナルによるMrp4-cAMP-PPARγを介した新規脂肪肝発症の分子機構の解明

    • Principal Investigator
      窪田 直人
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      Kumamoto University
  •  The Mechanisms of Selective Insulin Resistance for the development of Anti-Atherosclerotic DrugsPrincipal Investigator

    • Principal Investigator
      窪田 哲也
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      The Institute for Adult Diseases Asahi Life Foundation
  •  Autonomic nerve-mediated regulation of adipose tissue metabolism: parasympathetic nervous system and adiponectin secretion

    • Principal Investigator
      Kubota Naoto
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
    • Research Institution
      The University of Tokyo
  •  Mechanisms of Atherosclerosis via Selective Insulin Resistance in Endothelial CellsPrincipal Investigator

    • Principal Investigator
      Kubota Tetsuya
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      The Institute for Adult Diseases Asahi Life Foundation
  •  Development of molecular imaging of sarcoidosis: From evaluation of the animal model to clinical use

    • Principal Investigator
      Moroi Masao
    • Project Period (FY)
      2017 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Toho University
  •  IRS-2 in the CNS regulates food intake and glucose homeostasis

    • Principal Investigator
      INOUE MARIKO
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Metabolomics
    • Research Institution
      National Institutes of Biomedical Innovation, Health and Nutrition
      National Institute of Health and Nutrition
  •  肝臓における選択的インスリン抵抗性の解明Principal Investigator

    • Principal Investigator
      窪田 哲也
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Institute of Physical and Chemical Research
  •  Mice model of cardiac sarcoidosis to understand the pathogenesis and develop clinical diagnostic and therapeutic strategies.

    • Principal Investigator
      MOROI Masao
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Research Institute, International Medical Center of Japan
  •  The physiological and pathophysiological role of IRS-1 and IRS-2 in the liverPrincipal Investigator

    • Principal Investigator
      KUBOTA Tetsuya
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      National Institute of Health and Nutrition
  •  Insulin signaling in endothelial cells (insulin receptor substrate) and atherosclerosisPrincipal Investigator

    • Principal Investigator
      KUBOTA Tetsuya, 岩部 美紀
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      National Institute of Health and Nutrition

All 2023 2022 2021 2020 2019 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book

  • [Book] Medical Practice2021

    • Author(s)
      林高則,窪田直人
    • Total Pages
      7
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-21K19496
  • [Book] 肥満に伴う高インスリン血症による M2a-subtype マクロファージ活性化機構の破綻2021

    • Author(s)
      窪田哲也, 井上真理子, 窪田直人, 門脇 孝
    • Total Pages
      4
    • Publisher
      日本肥満学会誌
    • Data Source
      KAKENHI-PROJECT-19K08991
  • [Book] 月刊糖尿病2021

    • Author(s)
      澤田実佳,窪田 直人
    • Total Pages
      7
    • Publisher
      医学出版
    • Data Source
      KAKENHI-PROJECT-21K19496
  • [Book] 医学のあゆみ2021

    • Author(s)
      窪田直人,窪田哲也,門脇孝
    • Total Pages
      7
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-21K19496
  • [Book] 月刊糖尿病ライフ2021

    • Author(s)
      窪田直人
    • Total Pages
      4
    • Publisher
      日本糖尿病協会
    • Data Source
      KAKENHI-PROJECT-21K19496
  • [Book] Diabetes Strategy2016

    • Author(s)
      井上真理子、窪田哲也、窪田直人
    • Publisher
      (株)先端医学社
    • Data Source
      KAKENHI-PROJECT-26860702
  • [Book] Progress in Medicine2015

    • Author(s)
      窪田直人、井上真理子、門脇 孝
    • Publisher
      ライフサイエンス社
    • Data Source
      KAKENHI-PROJECT-26860702
  • [Book] Diabetes Journal 糖尿病と代謝2015

    • Author(s)
      井上真理子、窪田哲也、窪田直人、門脇 孝
    • Publisher
      (株)協和企画
    • Data Source
      KAKENHI-PROJECT-26860702
  • [Book] 栄養・食生活、「健康食品」と生活習慣病-C.糖尿病,健康・栄養食品アドバイザリースタッフ・テキストブック2010

    • Author(s)
      窪田哲也
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Journal Article] NFIA in adipocytes reciprocally regulates mitochondrial and inflammatory gene program to improve glucose homeostasis2023

    • Author(s)
      Hiraike Yuta、Saito Kaede、Oguchi Misato、Wada Takahito、Toda Gotaro、Tsutsumi Shuichi、Bando Kana、Sagawa Junji、Nagano Gaku、Ohno Haruya、Kubota Naoto、Kubota Tetsuya、Aburatani Hiroyuki、Kadowaki Takashi、Waki Hironori、Yanagimoto Shintaro、Yamauchi Toshimasa
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 120 Issue: 31

    • DOI

      10.1073/pnas.2308750120

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K16415, KAKENHI-PROJECT-23K15387, KAKENHI-PROJECT-22K08640, KAKENHI-PROJECT-22K08672, KAKENHI-PLANNED-19H05744
  • [Journal Article] Evaluation of glycated albumin levels in tears and saliva as a marker in patients with diabetes mellitus2023

    • Author(s)
      Aihara Masakazu、Jinnouchi Hideaki、Yoshida Akira、Ijima Hiroko、Sakurai Yoshitaka、Hayashi Takanori、Koizumi Chie、Kubota Tetsuya、Usami Satoshi、Yamauchi Toshimasa、Sakata Toshiya、Kadowaki Takashi、Kubota Naoto
    • Journal Title

      Diabetes Research and Clinical Practice

      Volume: 199 Pages: 110637-110637

    • DOI

      10.1016/j.diabres.2023.110637

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K08620, KAKENHI-PROJECT-22K08640, KAKENHI-PROJECT-21K16347
  • [Journal Article] Bi-weekly Glycated Albumin Measurement was Useful to Encourage Behavioral Changes in People with Type 2 Diabetes Mellitus2023

    • Author(s)
      Aihara Masakazu、Hayashi Takanori、Koizumi Chie、Sakurai Yoshitaka、Sawada Mika、Kubota Tetsuya、Kadowaki Takashi、Yamauchi Toshimasa、Kubota Naoto
    • Journal Title

      Diabetes Therapy

      Volume: 14 Issue: 10 Pages: 1711-1721

    • DOI

      10.1007/s13300-023-01452-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08620, KAKENHI-PROJECT-22K08640, KAKENHI-PROJECT-21K16347
  • [Journal Article] Association of self‐stigma with glycated hemoglobin: A single‐center, cross‐sectional study of adults with type?1 diabetes in Japan2023

    • Author(s)
      Hamano Shoko、Onishi Yukiko、Yoshida Yoko、Takao Toshiko、Tahara Tazu、Kikuchi Takako、Kobori Toshiko、Kubota Tetsuya、Iwamoto Masahiko、Kasuga Masato
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 14 Issue: 3 Pages: 479-485

    • DOI

      10.1111/jdi.13963

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K08640
  • [Journal Article] Exploring body weight-influencing gut microbiota by elucidating the association with diet and host gene expression2023

    • Author(s)
      Nemoto Shino、Kubota Tetsuya、Ohno Hiroshi
    • Journal Title

      Scientific Reports

      Volume: 13 Issue: 1 Pages: 5593-5593

    • DOI

      10.1038/s41598-023-32411-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08640
  • [Journal Article] Associations of sleep quality with the skeletal muscle strength in patients with type 2 diabetes with poor glycemic control2023

    • Author(s)
      Hayashi Takanori、Wada Nobuhiro、Kubota Tetsuya、Koizumi Chie、Sakurai Yoshitaka、Aihara Masakazu、Usami Satoshi、Yamauchi Toshimasa、Kubota Naoto
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 14 Issue: 6 Pages: 801-810

    • DOI

      10.1111/jdi.14007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08620, KAKENHI-PROJECT-22K08640, KAKENHI-PROJECT-21K16347
  • [Journal Article] Association of <scp>glucagon‐like peptide</scp>‐1 receptor agonist treatment with gastric residue in an esophagogastroduodenoscopy2023

    • Author(s)
      Kobori Toshiko、Onishi Yukiko、Yoshida Yoko、Tahara Tazu、Kikuchi Takako、Kubota Tetsuya、Iwamoto Masahiko、Sawada Tomonobu、Kobayashi Reo、Fujiwara Hiroaki、Kasuga Masato
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 14 Issue: 6 Pages: 767-773

    • DOI

      10.1111/jdi.14005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K08640
  • [Journal Article] Hepatic FASN deficiency differentially affects nonalcoholic fatty liver disease and diabetes in mouse obesity models2023

    • Author(s)
      Matsukawa Toshiya、Yagi Takashi、Uchida Tohru、Sakai Mashito、Mitsushima Masaru、Naganuma Takao、Yano Hiroyuki、Inaba Yuka、Inoue Hiroshi、Yanagida Keisuke、Uematsu Masaaki、Nakao Kazuki、Nakao Harumi、Aiba Atsu、Nagashima Yoji、Kubota Tetsuya、Kubota Naoto
    • Journal Title

      JCI Insight

      Volume: 8 Issue: 17

    • DOI

      10.1172/jci.insight.161282

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08640, KAKENHI-PROJECT-22K08667, KAKENHI-PROJECT-21K08243, KAKENHI-PROJECT-21K08542, KAKENHI-PROJECT-21K08579, KAKENHI-PROJECT-22K19545, KAKENHI-PROJECT-22K17790, KAKENHI-PROJECT-23K24390, KAKENHI-PROJECT-23K24764, KAKENHI-PROJECT-23K27996
  • [Journal Article] Gut microbial carbohydrate metabolism contributes to insulin resistance2023

    • Author(s)
      Takeuchi Tadashi、Kubota Tetsuya、Nakanishi Yumiko、Tsugawa Hiroshi、Suda Wataru、Kwon Andrew Tae-Jun、Yazaki Junshi、Ikeda Kazutaka、Nemoto Shino、Mochizuki Yoshiki、Kitami Toshimori、Yugi Katsuyuki、Mizuno Yoshiko、Yamamichi Nobutake、Yamazaki Tsutomu、Takamoto Iseki、Kubota Naoto、Kadowaki Takashi、
    • Journal Title

      Nature

      Volume: 621 Issue: 7978 Pages: 389-395

    • DOI

      10.1038/s41586-023-06466-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08640, KAKENHI-PROJECT-21H03178, KAKENHI-PROJECT-22H00452
  • [Journal Article] Chronic nicotinamide mononucleotide supplementation elevates blood nicotinamide adenine dinucleotide levels and alters muscle function in healthy older men.2022

    • Author(s)
      Igarashi M, Nakagawa-Nagahama Y, Miura M, Kashiwabara K, Yaku K, Sawada M, Sekine R, Fukamizu Y, Sato T, Sakurai T, Sato J, Ino K, Kubota N, Nakagawa T, Kadowaki T & Yamauchi T.
    • Journal Title

      npj Aging

      Volume: 8 Pages: 5-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K19496
  • [Journal Article] Association of insulin treatment with gastric residue during an esophagogastroduodenoscopy.2022

    • Author(s)
      Kobori T, Onishi Y, Iwamoto M, Kubota T, Kikuchi T, Tahara T, Takao T, Fujiwara H, Yoshida Y, Kasuga M.
    • Journal Title

      J Diabetes Investig

      Volume: 13 Issue: 3 Pages: 501-504

    • DOI

      10.1111/jdi.13665

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K08640
  • [Journal Article] Substitution of telemedicine for clinic visit during the COVID-19 pandemic of 2020: Comparison of telemedicine and clinic visit.2022

    • Author(s)
      Onishi Y, Ichihashi R, Yoshida Y, Tahara T, Kikuchi T, Kobori T, Kubota T, Iwamoto M, Hamano S, Kasuga M
    • Journal Title

      J Diabetes Investig

      Volume: 13 Issue: 9 Pages: 1617-1625

    • DOI

      10.1111/jdi.13826

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K08640
  • [Journal Article] Metabolic differences and differentially expressed genes between C57BL/6J and C57BL/6N mice substrains2022

    • Author(s)
      Nemoto S, Kubota T, Ohno H
    • Journal Title

      PLoS One

      Volume: 17 Issue: 12 Pages: e0271651-e0271651

    • DOI

      10.1371/journal.pone.0271651

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K08640
  • [Journal Article] The sodium-glucose co-transporter 2 inhibitor tofogliflozin suppresses atherosclerosis through glucose lowering in ApoE-deficient mice with streptozotocin-induced diabetes.2022

    • Author(s)
      Iwamoto M, Kubota T, Sakurai Y, Wada N, Shioda S, Yamauchi T, Kadowaki T, Kubota N
    • Journal Title

      Pharmacol. Res. Perspect.

      Volume: 10

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K19496
  • [Journal Article] A Case of Chronic Intestinal Pseudo-obstruction with Mitochondrial Diseases.2022

    • Author(s)
      Jinnouchi T, Sakurai Y, Miyoshi K, Koizumi C, Waki H, Kubota N, Yamauchi T.
    • Journal Title

      Intern. Med.

      Volume: 61 Pages: 469-474

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K19496
  • [Journal Article] Dietary Vitamin B1 Intake Influences Gut Microbial Community and the Consequent Production of Short-Chain Fatty Acids2022

    • Author(s)
      Park J, Hosomi K, Kawashima H, Chen YA, Mohsen A, Ohno H, Konishi K, Tanisawa K, Kifushi M, Kogawa M, Takeyama H, Murakami H, Kubota T, Miyachi M, Kunisawa J, Mizuguchi K.
    • Journal Title

      Nutrients

      Volume: 14 Issue: 10 Pages: 2078-2078

    • DOI

      10.3390/nu14102078

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08640, KAKENHI-PROJECT-21K15267, KAKENHI-PROJECT-22K15004, KAKENHI-PROJECT-20H04117
  • [Journal Article] The sodium‐glucose co‐transporter 2 inhibitor tofogliflozin suppresses atherosclerosis through glucose lowering in ApoE‐deficient mice with streptozotocin‐induced diabetes2022

    • Author(s)
      Iwamoto Masahiko、Kubota Tetsuya、Sakurai Yoshitaka、Wada Nobuhiro、Shioda Seiji、Yamauchi Toshimasa、Kadowaki Takashi、Kubota Naoto
    • Journal Title

      Pharmacology Research & Perspectives

      Volume: 10 Issue: 4

    • DOI

      10.1002/prp2.971

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08620, KAKENHI-PROJECT-22K08640, KAKENHI-PROJECT-20K20392, KAKENHI-PROJECT-23K24437
  • [Journal Article] Lack of Brain Insulin Receptor Substrate-1 Causes Growth Retardation, With Decreased Expression of Growth Hormone?Releasing Hormone in the Hypothalamus2021

    • Author(s)
      Hayashi Takanori、Kubota Tetsuya、Mariko Inoue、Takamoto Iseki、Aihara Masakazu、Sakurai Yoshitaka、Wada Nobuhiro、Miki Takashi、Yamauchi Toshimasa、Kubota Naoto、Kadowaki Takashi
    • Journal Title

      Diabetes

      Volume: 70 Issue: 8 Pages: 1640-1653

    • DOI

      10.2337/db20-0482

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07281, KAKENHI-PROJECT-19K08991, KAKENHI-PROJECT-19K17977, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-21K19496
  • [Journal Article] Stool pattern is associated with not only the prevalence of tumorigenic bacteria isolated from fecal matter but also plasma and fecal fatty acids in healthy Japanese adults2021

    • Author(s)
      Watanabe Daiki、Murakami Haruka、Ohno Harumi、Tanisawa Kumpei、Konishi Kana、Todoroki-Mori Kikue、Tsunematsu Yuta、Sato Michio、Ogata Yuji、Miyoshi Noriyuki、Kubota Naoto、Kunisawa Jun、Wakabayashi Keiji、Kubota Tetsuya、Watanabe Kenji、Miyachi Motohiko
    • Journal Title

      BMC Microbiology

      Volume: 21 Issue: 1 Pages: 196-196

    • DOI

      10.1186/s12866-021-02255-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08991, KAKENHI-PROJECT-20H04117, KAKENHI-PROJECT-19H04065, KAKENHI-PROJECT-21K19496
  • [Journal Article] Diabetes management by either telemedicine or clinic visit improved glycemic control during the coronavirus disease 2019 pandemic state of emergency in Japan2021

    • Author(s)
      Onishi Yukiko、Yoshida Yoko、Takao Toshiko、Tahara Tazu、Kikuchi Takako、Kobori Toshiko、Kubota Tetsuya、Shimmei Asuka、Iwamoto Masahiko、Kasuga Masato
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 13 Issue: 2 Pages: 386-390

    • DOI

      10.1111/jdi.13546

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08991
  • [Journal Article] Protein intake after the initiation of chemotherapy is an independent prognostic factor for overall survival in patients with unresectable pancreatic cancer: A prospective cohort study2021

    • Author(s)
      Hasegawa Yoko、Ijichi Hideaki、Saito Kei、Ishigaki Kazunaga、Takami Maki、Sekine Rie、Usami Satoshi、Nakai Yousuke、Koike Kazuhiko、Kubota Naoto
    • Journal Title

      Clinical Nutrition

      Volume: 40 Issue: 7 Pages: 4792-4798

    • DOI

      10.1016/j.clnu.2021.06.011

    • Data Source
      KAKENHI-PROJECT-21K19496
  • [Journal Article] A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice2021

    • Author(s)
      Furuzono Shinji、Kubota Tetsuya、Taura Junki、Konishi Masahiro、Naito Asuka、Tsutsui Masato、Karasawa Hiroshi、Kubota Naoto、Kadowaki Takashi
    • Journal Title

      Communications Biology

      Volume: 4 Issue: 1 Pages: 994-994

    • DOI

      10.1038/s42003-021-02491-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08991, KAKENHI-PROJECT-21K19496
  • [Journal Article] Midlobular zone 2 hepatocytes: A gatekeeper of liver homeostasis2021

    • Author(s)
      Kubota Naoto、Kubota Tetsuya、Kadowaki Takashi
    • Journal Title

      Cell Metabolism

      Volume: 33 Issue: 5 Pages: 855-856

    • DOI

      10.1016/j.cmet.2021.04.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08991, KAKENHI-PROJECT-19H01052
  • [Journal Article] AST-120 Treatment Alters the Gut Microbiota Composition and Suppresses Hepatic Triglyceride Levels in Obese Mice2021

    • Author(s)
      Hiraga Yuki、Kubota Tetsuya、Katoh Makoto、Horai Yasushi、Suzuki Hiroyuki、Yamashita Yusuke、Hirata Rieko、Moroi Masao
    • Journal Title

      Endocrine Research

      Volume: 46 Issue: 4 Pages: 178-185

    • DOI

      10.1080/07435800.2021.1927074

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08991
  • [Journal Article] Association between tear and blood glucose concentrations: Random intercept model adjusted with confounders in tear samples negative for occult blood2020

    • Author(s)
      Aihara Masakazu、Kubota Naoto、Minami Takahiro、Shirakawa Rika、Sakurai Yoshitaka、Hayashi Takanori、Iwamoto Masahiko、Takamoto Iseki、Kubota Tetsuya、Suzuki Ryo、Usami Satoshi、Jinnouchi Hideaki、Aihara Makoto、Yamauchi Toshimasa、Sakata Toshiya、Kadowaki Takashi
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 12 Issue: 2 Pages: 266-276

    • DOI

      10.1111/jdi.13344

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08991, KAKENHI-PROJECT-19K17977, KAKENHI-PROJECT-18H02860
  • [Journal Article] LPIAT1/MBOAT7 depletion increases triglyceride synthesis fueled by high phosphatidylinositol turnover2020

    • Author(s)
      Tanaka Y, Shimanaka Y, Caddeo A, Kubo T, Mao Y, Kubota T, Kubota N, Yamauchi T, Mancina RM, Baselli G, Luukkonen P, Pihlajamaki J, Yki-Jarvinen H, Valenti L, Arai H, Romeo S, Kono N.
    • Journal Title

      Gut

      Volume: 70 Issue: 1 Pages: 180

    • DOI

      10.1136/gutjnl-2020-320646

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H05053, KAKENHI-PROJECT-19K08991, KAKENHI-PROJECT-20J14922, KAKENHI-PLANNED-17H06418, KAKENHI-PROJECT-17H06164, KAKENHI-PROJECT-20H03380
  • [Journal Article] Insulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation2020

    • Author(s)
      Toda G、Soeda K、Okazaki Y、Kobayashi N、Masuda Y、Arakawa N、Suwanai H、Masamoto Y、Izumida Y、Kamei N、Sasako T、Suzuki R、Kubota T、Kubota N、Kurokawa M、Tobe K、Noda T、Honda K、Accili D、Yamauchi T、Kadowaki T、Ueki K
    • Journal Title

      Molecular Cell

      Volume: 79 Issue: 1 Pages: 1-2

    • DOI

      10.1016/j.molcel.2020.04.033

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07898, KAKENHI-PROJECT-19K08991, KAKENHI-PROJECT-19K17954, KAKENHI-PROJECT-18H04052, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-17K00846, KAKENHI-PROJECT-18K15075
  • [Journal Article] Differential effects of diet- and genetically-induced brain insulin resistance on amyloid pathology in a mouse model of Alzheimer’s disease2019

    • Author(s)
      Tomoko Wakabayashi, Kazuki Yamaguchi, Kentaro Matsui, Toshiharu Sano, Tetsuya Kubota, Tadafumi Hashimoto, Ayako Mano, Kaoru Yamada, Yuko Matsuo, Naoto Kubota, Takashi Kadowaki, Takeshi Iwatsubo
    • Journal Title

      Molecular Neurodegeneration

      Volume: 14 Issue: 1 Pages: 15-15

    • DOI

      10.1186/s13024-019-0315-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07364, KAKENHI-PROJECT-19K08991, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-26000012, KAKENHI-PROJECT-17H04193, KAKENHI-PROJECT-18H02860
  • [Journal Article] Innate Lymphoid Cells in the Induction of Obesity2019

    • Author(s)
      Sasaki T, Moro K, Kubota T, Kubota N, Kato T, Ohno H, Nakae S, Saito H, Koyasu S.
    • Journal Title

      Cell Rep

      Volume: 28 Issue: 1 Pages: 202-217

    • DOI

      10.1016/j.celrep.2019.06.016

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08991, KAKENHI-PROJECT-18H05286, KAKENHI-PROJECT-18H02847
  • [Journal Article] ソマトスタチン受容体シンチグラフィーによる心臓サルコイドーシスの活動性炎症評価2019

    • Author(s)
      粟屋徹, 南本亮吾, 窪田和雄, 久保田修司, 岡崎徹, 岡崎修, 原久男, 廣井秀雄, 廣江道昭, 諸井雅男
    • Journal Title

      日本サルコイドーシス/肉牙腫性疾患学会雑誌

      Volume: 39 Pages: 55-64

    • NAID

      130007777438

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10454
  • [Journal Article] Insulin receptor substrate-2 (irs2) in endothelial cells plays a crucial role in insulin secretion2015

    • Author(s)
      Hashimoto, S. Kubota, N. Sato, H. Sasaki, M. Takamoto, I. Kubota, T. Nakaya, K. Noda, M. Ueki, K. Kadowaki, T.
    • Journal Title

      Diabetes

      Volume: 64 Issue: 3 Pages: 876-886

    • DOI

      10.2337/db14-0432

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249053, KAKENHI-PROJECT-24390232, KAKENHI-PROJECT-25461371, KAKENHI-PROJECT-26000012
  • [Journal Article] Long fasting is effective in inhibiting physiological myocardial 18F-FDG uptake and for evaluating active lesions of cardiac sarcoidosis2014

    • Author(s)
      Miyako Morooka, Masao Moroi, Kimiichi Uno, Kimiteru Ito, Jin Wu, Takashi Nakagawa, Kazuo Kubota, Ryogo Minamimoto, Yoko Miyata, Momoko Okasaki, Osamu Okazaki, Yoshihito Yamada, Tetsuo Yamaguchi, Michiaki Hiroe
    • Journal Title

      EJNMMI Research

      Volume: 4 Issue: 1 Pages: 1-1

    • DOI

      10.1186/2191-219x-4-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590907, KAKENHI-PROJECT-24406026, KAKENHI-PROJECT-24591807
  • [Journal Article] TCF7L2 in mouse pancreatic beta cells plays a crucial role in glucose homeostasis by regulating beta cell mass.2014

    • Author(s)
      Takamoto I, Kubota N, Nakaya K, Kumagai K, Hashimoto S, Kubota T, Inoue M, Kajiwara E, Katsuyama H, Obata A, Sakurai Y, Iwamoto M, Kitamura T, Ueki K, Kadowaki T
    • Journal Title

      Diabetologia

      Volume: 57 Issue: 3 Pages: 542-553

    • DOI

      10.1007/s00125-013-3131-6

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390232, KAKENHI-PROJECT-25221307, KAKENHI-PROJECT-25461371, KAKENHI-PROJECT-25860741
  • [Journal Article] Vagal hyperactivity due to ventromedial hypothalamic lesions increases adiponectin production and release.2014

    • Author(s)
      Suzuki Y, Shimizu H, Ishizuka N, Kubota N, Kubota T, Senoo A, Kageyama H, Osaka T, Hirako S, Kim HJ, Matsumoto A, Shioda S, Mori M, Kadowaki T, Inoue S.
    • Journal Title

      Diabetes.

      Volume: 63(5) Issue: 5 Pages: 1637-1648

    • DOI

      10.2337/db13-0636

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22126004, KAKENHI-PLANNED-22126010, KAKENHI-PROJECT-24390232, KAKENHI-PROJECT-24590241, KAKENHI-PROJECT-25221307, KAKENHI-PROJECT-25461371, KAKENHI-PROJECT-25670767, KAKENHI-PROJECT-25750053, KAKENHI-PROJECT-26000012
  • [Journal Article] Long fasting is effective in inhibiting physiological myocardial 18F-FDG uptake and for evaluating active lesions of cardiac sarcoidosis2014

    • Author(s)
      Morooka M, Moroi M, Uno K, Ito K, Wu J, Nakagawa T, Kubota K, Minamimoto R, Miyata Y, Okasaki M, Okazaki O, Yamada Y, Yamaguchi T, Hiroe M
    • Journal Title

      EJNMMI Res

      Volume: 2;4(1)(Epub ahead of print) Pages: 1-1

    • Data Source
      KAKENHI-PROJECT-23590907
  • [Journal Article] Dipeptidyl peptidase-4 inhibitor anagliptin ameliorates diabetes in mice with haploinsufficiency of glucokinase on a high-fat diet.2013

    • Author(s)
      Nakaya K, Kubota N, Takamoto I, Kubota T, Katsuyama H, Sato H, Tokuyama K, Hashimoto S, Goto M, Jomori T, Ueki K, Kadowaki T
    • Journal Title

      Metabolism

      Volume: 62 Issue: 7 Pages: 939-951

    • DOI

      10.1016/j.metabol.2013.01.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25221307, KAKENHI-PROJECT-25253068, KAKENHI-PROJECT-25461371
  • [Journal Article] Relationship of living circumstances with dietary patterns of Great East Japan Earthquake victims.2013

    • Author(s)
      Nishi N, Yoshimura E, Ishikawa-Takata K, Tsuboyama-Kasaoka N, Kubota T, Miyachi M, Tokudome S, Yokoyama Y, Sakata K, Kobayashi S, Ogawa A
    • Journal Title

      J Epidemiol

      Volume: 5 Pages: 376-381

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461371
  • [Journal Article] The role of endothelial insulin signaling in the regulation of glucose metabolism.2013

    • Author(s)
      Kubota T, Kubota N, Kadowaki T
    • Journal Title

      Rev. Endocr. Metab. Disord.

      Volume: 14 Issue: 2 Pages: 207-216

    • DOI

      10.1007/s11154-013-9242-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25221307, KAKENHI-PROJECT-25253068, KAKENHI-PROJECT-25461371
  • [Journal Article] 東日本大震災被災者健康調査の質問票における身体活動関連項目の妥当性および再現性の検討2013

    • Author(s)
      村上春香、吉村英一、高田和子、長谷川祐子、窪田哲也、笠岡信代、西信雄、横山由香里、八重樫由美、坂田清美、小林誠一郎、宮地元彦、徳留信寛
    • Journal Title

      日本公衆衛生雑誌

      Volume: 60 Pages: 222-230

    • NAID

      10031168563

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461371
  • [Journal Article] Combined treatment with low-dose pioglitazone and beraprost sodium improves glucose intolerance without causing body weight gain2013

    • Author(s)
      Kumagai H、Kubota N、Kubota T、Takahashi T、Inoue M、Kawai T、Iwayama K、Moroi M、Sugi K、Kadowaki T
    • Journal Title

      Diabetology International

      Volume: 4 Pages: 226-232

    • NAID

      40019935789

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461371
  • [Journal Article] Impaired insulin signaling in the endothelial cells reduces insulin-induced glucose uptake by the skeletal muscle2011

    • Author(s)
      Kubota T, Kubota N, et al
    • Journal Title

      Cell Metab

      Volume: 13 Pages: 294-307

    • URL

      http://dx.doi.org/10.1016/j.cmet.2011.01.018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Journal Article] Impaired insulin signaling in the endothelial cells reduces insulin-induced glucose uptake by the skeletal muscle2011

    • Author(s)
      Kubota T, Kubota N, Kumagai H, Yamaguchi S, Kozono H, Takahashi T, Inoue M, Itoh S, Takamoto I, Sasako T, Kumagai K, Kawai T, Hashimoto S, Kobayashi T, Sato M, Tokuyama K, Nishimura S, Tsunoda M, Ide T, Murakami K, Yamazaki T, Ezaki O, Kawamura K, Masuda H, Moroi M, Sugi K, Oike Y, Shimokawa H, Yanagihara N, Tsutsui M, Terauchi Y, Tobe K, Nagai R, Kamata K, Inoue K, Kodama T, Ueki K, Kadowaki T
    • Journal Title

      Cell Metabolism

      Volume: 13 Pages: 294-307

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Journal Article] A liver-derived secretory protein, selenoprotein p, causes insulin resistance.2010

    • Author(s)
      Misu H, Takamura T, Takayama H, Hayashi H, Matsuzawa-Nagata N, Kurita S, Ishikura K, Ando H, Takeshita Y, Ota T, Sakurai M, Yamashita T, Mizukoshi E, Yamashita T, Honda M, Miyamoto K, Kubota T, Kubota N, Kadowaki T, Kim HJ, Lee IK, Minokoshi Y, Saito Y, Takahashi K, Yamada Y, Takakura N, Kaneko S.
    • Journal Title

      Cell Metabolism

      Volume: 12 Pages: 483-495

    • NAID

      120002661942

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Journal Article] A liver-derived secretory protein, selenoprotein p, causes insulin resistance2010

    • Author(s)
      Misu H, Takamura T, Takayama H, Hayashi H, Matsuzawa-Nagata N, Kurita S, Ishikura K, Ando H, Takeshita Y, Ota T, Sakurai M, Yamashita T, Mizukoshi E, Yamashita T, Honda M, Miyamoto K, Kubota T, Kubota N, Kadowai T, et al
    • Journal Title

      Cell Metab

      Volume: 12 Pages: 483-495

    • NAID

      120002661942

    • URL

      http://dx.doi.org/10.1016/j.cmet.2010.09.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] In-111 pentetreotideの心筋炎症部位への集積機序の検討2023

    • Author(s)
      諸井雅男、今中恭子、窪田哲也、瀧淳一、廣江道昭
    • Organizer
      第42回日本画像医学会 学術集会
    • Data Source
      KAKENHI-PROJECT-17K10454
  • [Presentation] 肥満症の食事療法・栄養指導2022

    • Author(s)
      窪田直人
    • Organizer
      第43回日本肥満学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K19496
  • [Presentation] 2型糖尿病の病態と薬物治療2022

    • Author(s)
      窪田直人
    • Organizer
      第67回日本内科学会信越支部生涯教育講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K19496
  • [Presentation] 2型糖尿病への臨床栄養学の進歩 糖尿病の食事療法 最新の知見も含めて2022

    • Author(s)
      窪田直人
    • Organizer
      第44回日本臨床栄養学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K19496
  • [Presentation] 高インスリン血症によるM2マクロファージ活性化障害2021

    • Author(s)
      窪田 哲也, 窪田 直人, 門脇 孝
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K08991
  • [Presentation] 糖尿病の病態-immunometabolism(免疫代謝学)からのアプローチ高インスリン血症によるM2マクロファージ活性化障害2021

    • Author(s)
      窪田哲也
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K19496
  • [Presentation] ヒトの腸内細菌叢とインスリン抵抗性におけるMulti-Omics解析2021

    • Author(s)
      窪田 直人, 竹内 直志, 窪田 哲也, 水野 由子, 山道 信毅, 大野 博司, 門脇 孝
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K08991
  • [Presentation] 脂肪細胞+炎症:肥満におけるM2マクロファージ活性化障害機構2021

    • Author(s)
      窪田哲也
    • Organizer
      第41回日本肥満学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K19496
  • [Presentation] ヒトの腸内細菌叢とインスリン抵抗性におけるMulti-Omics解析2021

    • Author(s)
      窪田直人
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K19496
  • [Presentation] 肥満2型糖尿病における栄養療法を考える:肥満2型糖尿病における栄養療法の現状と課題2021

    • Author(s)
      窪田直人
    • Organizer
      第41回日本肥満学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K19496
  • [Presentation] 経口吸着炭薬は肥満2型糖尿病モデルマウスの脂肪肝 を抑制する2021

    • Author(s)
      窪田 哲也, 平賀 由起, 加藤 誠, 諸井 雅男
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-19K08991
  • [Presentation] 院における過去30年間の初診時糖尿病性網膜症の頻度や重症度の変遷2020

    • Author(s)
      窪田哲也、吉田洋子、高尾淑子、大西由希子、田原たづ、菊池貴子、震明あすか、岩本真彦、小堀勤子、春日雅人
    • Organizer
      第35回日本糖尿病合併症学会
    • Data Source
      KAKENHI-PROJECT-19K08991
  • [Presentation] 病態発症における臓器内・臓器間のインスリン作用失調メカニズム2020

    • Author(s)
      窪田哲也
    • Organizer
      インスリン分泌セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K08991
  • [Presentation] 当院における2型糖尿病患者の初診時臨床像の過去30年間の変遷2020

    • Author(s)
      小堀勤子, 大西 由希子, 吉田洋子, 高尾 淑子, 田原たづ, 菊池 貴子, 窪田 哲也, 岩本 真彦, 震明 あすか, 春日 雅人
    • Organizer
      第117回日本内科学会
    • Data Source
      KAKENHI-PROJECT-19K08991
  • [Presentation] 化合物Xは骨格筋特異的 にGLUT4の translocationを増強し糖取り込みを改善する2020

    • Author(s)
      窪田哲也、田浦順樹、古薗信二、唐澤博史、門脇孝、窪田直人:
    • Organizer
      第63回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-19K08991
  • [Presentation] 肥満におけるM2マクロファージ活性化障害機構2020

    • Author(s)
      窪田哲也、窪田直人、門脇孝
    • Organizer
      第41回日本肥満学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K08991
  • [Presentation] 血管内皮細胞のIrs2は動脈硬化に抑制的に働く2019

    • Author(s)
      窪田哲也、窪田直人、林 高則、相原允一、山内敏正、門脇 孝
    • Organizer
      第23回日本心血管内分泌学会
    • Data Source
      KAKENHI-PROJECT-19K08991
  • [Presentation] 血管内皮細胞のIRS-2は動脈硬化 抑制に働く2019

    • Author(s)
      窪田哲也、窪田直人、林高則、相原允一、山内敏正、門脇孝
    • Organizer
      第62回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-19K08991
  • [Presentation] チアゾリジン誘導体はアディポネクチン依存性・非依存性に動脈硬化を抑制する2015

    • Author(s)
      井上真理子、窪田直人、窪田哲也、林 高則、相原允一、山内敏正、植木浩二郎、門脇 孝
    • Organizer
      第58回日本糖尿病学会年次学術集会
    • Place of Presentation
      山口県下関市
    • Year and Date
      2015-05-23
    • Data Source
      KAKENHI-PROJECT-26860702
  • [Presentation] Insulin and leptin in the CNS regulate food intake and glucose homeostasis2015

    • Author(s)
      Mariko Inoue, Naoto Kubota, Tetsuya Kubota, Iseki Takamoto, Toshimasa Yamauchi, Kohjiro Ueki,Takashi Kadowaki
    • Organizer
      Keystone Symposia
    • Place of Presentation
      京都府京都市
    • Year and Date
      2015-10-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26860702
  • [Presentation] チアゾリジン誘導体の動脈硬化抑制におけるアディポネクチンの役割の解明2015

    • Author(s)
      窪田哲也、窪田直人、井上真理子、林 高則、相原允一、高本偉碩、山内敏正、植木浩二郎、門脇 孝
    • Organizer
      第29回日本糖尿病・肥満動物学会年次学術集会
    • Place of Presentation
      京都 京都大学
    • Year and Date
      2015-02-14
    • Data Source
      KAKENHI-PROJECT-25461371
  • [Presentation] 動脈硬化における血管内皮細胞のIRS-2の役割の解明2014

    • Author(s)
      窪田 哲也, 窪田 直人, 井上 真理子, 林 高則, 相原 允一, 高本 偉碵, 山内 敏正, 植木 浩二郎, 門脇 孝
    • Organizer
      第57回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪 国際会議場
    • Year and Date
      2014-05-24
    • Data Source
      KAKENHI-PROJECT-25461371
  • [Presentation] 中枢のIRS-2を介した糖代謝・摂食調節2014

    • Author(s)
      井上真理子、窪田直人、窪田哲也、林 高則、相原 允一、 山内 敏正、植木 浩二郎、門脇 孝
    • Organizer
      第57回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2014-05-23
    • Data Source
      KAKENHI-PROJECT-26860702
  • [Presentation] Pioglitazone Ameliorates Cuff Induced Neointimal Formation by both Adiponectin Dependent and Independent Pathways2014

    • Author(s)
      Kubota T, Kubota N, Inoue M, Takamoto I, Yamauchi T, Ueki K, Kadowaki T
    • Organizer
      9th Metabolic Syndrome, Type 2 Diabetes and Atherosclerosis Congress
    • Place of Presentation
      Kyoto Kyoto international conference center
    • Year and Date
      2014-09-13
    • Data Source
      KAKENHI-PROJECT-25461371
  • [Presentation] 中枢のIRS-2を介した糖代謝・摂食調節2014

    • Author(s)
      井上真理子、窪田直人、窪田哲也、林 高則、相原 允一、山内 敏正、植木 浩二郎、門脇 孝
    • Organizer
      第29回日本糖尿病合併症学会
    • Place of Presentation
      東京シェーンバッハ・サボー
    • Year and Date
      2014-10-04
    • Data Source
      KAKENHI-PROJECT-26860702
  • [Presentation] IRS-2 in the brain regulates hepatic glucose production and food intake2014

    • Author(s)
      井上真理子、窪田直人、窪田哲也、林 高則、相原 允一、 山内 敏正、植木 浩二郎、門脇 孝
    • Organizer
      第19回アディポサイエンス・シンポジウム
    • Place of Presentation
      大阪千里ライフサイエンスセンター
    • Year and Date
      2014-08-23
    • Data Source
      KAKENHI-PROJECT-26860702
  • [Presentation] 血管内皮細胞のIRS-2は動脈硬化を抑制する2014

    • Author(s)
      窪田 哲也, 窪田 直人, 井上 真理子, 林 高則, 相原 允一, 高本 偉碩, 山内 敏正, 植木 浩二郎, 門脇 孝
    • Organizer
      第35回日本肥満学会
    • Place of Presentation
      宮崎 フェニックス・シーガイヤ
    • Year and Date
      2014-10-25
    • Data Source
      KAKENHI-PROJECT-25461371
  • [Presentation] チアゾリジン誘導体はアディポネクチン依存性・非依存性にカフ障害性の内膜肥厚を抑制する2014

    • Author(s)
      窪田 哲也, 窪田 直人, 佐藤 寛之, 井上 真理子, 高本 偉碩, 山内 敏正, 植木 浩二郎, 門脇 孝
    • Organizer
      第87回内分泌学会学術総会
    • Place of Presentation
      福岡 サンパレスホテル
    • Year and Date
      2014-04-26
    • Data Source
      KAKENHI-PROJECT-25461371
  • [Presentation] チアゾリジン誘導体はアディポネクチン依存性・非依存性に動脈硬化を抑制する2012

    • Author(s)
      窪田哲也、窪田直人、佐藤寛之、岩村智勝、井上真理子、林高則、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第26回日本糖尿病・肥満動物学会年次学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2012-02-18
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] サルコイドーシス患者の心臓病変評価におけるFDG-PETとBMIPP-SPECTの有用性2012

    • Author(s)
      中川尭、廣江道昭、諸岡都、南本亮吾、伊藤公輝、窪田和雄、山田嘉仁、山口哲生、長田まこと、脇屋桃子、上村宗弘、池田長生、田守唯一、山本正也、伊藤信吾、岡崎修、原久男、諸井雅男
    • Organizer
      第22回日本心臓郭医学会総会・学術大会
    • Place of Presentation
      金沢
    • Year and Date
      2012-06-23
    • Data Source
      KAKENHI-PROJECT-23590907
  • [Presentation] 肝臓の糖・脂質代謝におけるIRS1、IRS2の役割2012

    • Author(s)
      岩村智勝,窪田直人,窪田哲也,井上真理子,佐藤寛之,林高則,高本偉碩,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第15回日本病態栄養学会年次学術集会
    • Place of Presentation
      京都
    • Year and Date
      2012-01-14
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 中枢のIRS-2は肝臓のインスリン感受性を調節する2012

    • Author(s)
      井上真理子、窪田直人、窪田哲也、熊谷洋紀、河合智子、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第26回日本糖尿病・肥満動物学会年次学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2012-02-17
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Significance of cardiac imaging with F-18-DG-PET and Iodine-123 BMIPP SPECT in patients with known or suspected cardiac sarcoidosis2012

    • Author(s)
      Nakagawa, T, Hiroe M, Morooka M, Minamimoto R, Ito K, Kubota K, Yamada Y, Yamaguchi T, Nagata M, Wakiya M, Kamimura M, Ikeda N, Tamori Y , Yamamoto M, Itoh S, Okazaki O, Hara H, Moroi M
    • Organizer
      The 76th Annual Scientific Meeting of the Japanese Circulation Society
    • Place of Presentation
      Fukuoka
    • Year and Date
      2012-03-17
    • Data Source
      KAKENHI-PROJECT-23590907
  • [Presentation] 血管内皮細胞インスリンシグナル障害はインスリン依存性の骨格筋の糖取り込み障害を惹起する2011

    • Author(s)
      窪田直人,窪田哲也,植木浩二郎,門脇孝
    • Organizer
      第61回日本体質医学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-10-08
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] DPP-4阻害薬の2型糖尿病モデル動物に対する抗糖尿病作用2011

    • Author(s)
      中屋恵三,窪田直人,高本偉碩,窪田哲也,佐藤寛之,勝山修行,橋本信嗣,後藤守兄,城森孝仁,植木浩二郎,門脇孝
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] インスリン感受性調節におけるインターロイキン33の役割について2011

    • Author(s)
      渡部拓,竹内倫徳,窪田直人,坂上慎二,後藤知紗,辻野一三,窪田哲也,三品昌美,門脇孝,西村正治
    • Organizer
      第32回日本肥満学会
    • Place of Presentation
      淡路
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] The Effects of SK-o4os, a highly selective DPP-4 inhibitor, on(s-cell mass and function in haploinsufficiency of) s-cellspecific glucokinase mice on a high-fat diet2011

    • Author(s)
      Keizo Nakaya, Naoto Kubota, Iseki Takamoto, Tetsuya Kubota, Hisayuki Katsuyama, Hiroyuki Sate, Shinji Hashimoto, Moritaka Goto, Takahito Jomori, Kohjiro Ueki, and Takashi Kadowaki
    • Organizer
      71th American Diabetes Association's Scientific Sessions
    • Place of Presentation
      San diego, USA
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 肝臓の糖・脂質代謝におけるIRS-1、IRS-2の役割2011

    • Author(s)
      窪田直人,窪田哲也,熊谷洋紀,井上真理子,渡部拓,西村正浩,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第84回日本内分泌学会学術総会
    • Place of Presentation
      神戸
    • Year and Date
      2011-04-22
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] チアゾリジン誘導体の抗動脈硬化作用におけるアディポネクチンの役割の解明2011

    • Author(s)
      窪田哲也、窪田直人、佐藤寛之、岩村智勝、井上真理子、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第32回日本肥満学会
    • Place of Presentation
      淡路
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 中枢のIRS-2の糖代謝調節における役割の解明脳特異的IRS-2欠損マウスを用いて2011

    • Author(s)
      井上真理子, 窪田直人, 窪田哲也, 熊谷洋紀, 河合智子, 山内敏正, 植木浩二郎, 門脇孝
    • Organizer
      第84回日本内分泌学会学術総会
    • Place of Presentation
      神戸
    • Year and Date
      2011-04-22
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 中枢のIRS-2の糖代謝調節における役割の解明-脳特異的IRS-2欠損マウスを用いて-2011

    • Author(s)
      井上真理子,窪田直人,窪田哲也,熊谷洋紀,河合智子,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第25回日本糖尿病・肥満動物学会年次学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-05
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 肥満・インスリン分泌不全を呈する2型糖尿病モデル動物に対するDPP-4阻害薬の長期投与効果2011

    • Author(s)
      中屋恵三,佐藤寛之,窪田直人,高本偉碩,窪田哲也,勝山修行,橋本信嗣,後藤守兄,城森孝仁,植木浩二郎,門脇孝
    • Organizer
      第25回日本糖尿病・肥満動物学会年次学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-05
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 血管内皮細胞インスリンシグナル障害はインスリン依存性の骨格筋の糖取り込み障害を惹起する2011

    • Author(s)
      窪田哲也、窪田直人、熊谷洋紀、井上真理子、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 肝臓の糖・脂質代謝におけるIRS1、IRS2の役割2011

    • Author(s)
      窪田直人,窪田哲也,熊谷洋紀,井上真理子,渡部拓,西村正治,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 骨格筋のインスリン感受性調節における血管内皮細胞のインスリンシグナルの役割の解明2011

    • Author(s)
      窪田哲也,窪田直人,熊谷洋紀,井上真理子,河合智子,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第25回日本糖尿病・肥満動物学会年次学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-05
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 膵β細胞のTcf712は膵β細胞量維持に重要な役割を果たしている2011

    • Author(s)
      高本偉碩,窪田直人,中屋恵三,熊谷勝義,小畑淳史,勝山修行,窪田哲也,植木浩二郎,門脇孝
    • Organizer
      第25回日本糖尿病・肥満動物学会年次学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-05
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Impaired insulin signaling in the endothelial cells reduces insulininduced glucose uptake by the skeletal muscle2011

    • Author(s)
      Naoto Kubota, Tetsuya Kubota, Hiroki Kumagai, Marika Inoue, Toshimasa Yamauchi, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      Scientific Sessions 71th American Diabetes Association
    • Place of Presentation
      San Diego
    • Year and Date
      2011-06-26
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] The Effects of SK-0403, a highly selective DPP-4 inhibitor, on β-cell mass and function in haploinsufficiency of β-cell-specific glucokinase mice on a high-fat diet2011

    • Author(s)
      Keizo Nakaya, Naoto Kubota, Iseki Takamoto, Tetsuya Kubota, Hisayuki Katsuyama, Hiroyuki Sato, Shinji Hashimoto, Moritaka Goto, Takahito Jomori, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      71th American Diabetes Association's Scientific Sessions
    • Place of Presentation
      San Diego
    • Year and Date
      2011-06-26
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Impaired Insulin Signaling in the Endothelial Cells Reduces Insulininduced Glucose Uptake by the Skeletal Muscle2011

    • Author(s)
      Tetsuya Kubota, Naoto Kubota, Tomokatsu Iwamura, Marika Inoue, Hiroyuki Sate, Takanori Hayashi, Iseki Takamoto, Toshimasa Yamauchi, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      The 16th Japan-Korea Symposium on Diabetes Mellitus
    • Place of Presentation
      Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 膵β細胞のTcf712は膵β細胞量維持に重要な役割を果たしている2011

    • Author(s)
      高本偉碩,窪田直人,小畑淳史,熊谷勝義,勝山修行,窪田哲也,北村忠弘,植木浩二郎,門脇孝
    • Organizer
      第61回日本体質医学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-10-08
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 中枢のIRS-2の糖代謝調節における役割の解明-脳特異的IRS-2欠損マウスを用いて-2011

    • Author(s)
      井上真理子、窪田直人、窪田哲也、熊谷洋紀、河合智子、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 膵β細胞のTcf712は膵β細胞量維持に重要な役割を果たしている2011

    • Author(s)
      高本偉碩,窪田直人,中屋恵三,熊谷勝義,小畑淳史,勝山修行,窪田哲也,北村忠弘,植木浩二郎,門脇孝
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Impaired Insulin Signaling in the Endothelial Cells Reduces Insulin-induced Glucose Uptake by the Skeletal Muscle2011

    • Author(s)
      Tetsuya Kubota, Naoto Kubota, Tomokatsu Iwamura, Mariko Inoue, Hiroyuki Sato, Takanori Hayashi, Iseki Takamoto, Toshimasa Yamauchi, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      The 16th Japan-Korea Symposium on Diabetes Mellitus
    • Place of Presentation
      Tokyo
    • Year and Date
      2011-10-22
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] PGI2アナログは血管内皮細胞のインスリンシグナルを介して肥満モデルマウスの骨格筋のインスリン依存性糖取り込みを改善する2011

    • Author(s)
      窪田哲也、窪田直人、岩村智勝、井上真理子、佐藤寛之、高本偉碩、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第29回肥満症治療学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2011-06-10
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 視床下部腹内側核(VMH)破壊肥満モデルではアディポネクチン(ADN)産生が亢進する2011

    • Author(s)
      鈴木洋子, 石塚典子, 清水弘行, 大坂寿雅, 窪田直人, 窪田哲也, 門脇孝, 井上修二
    • Organizer
      第32回日本肥満学会
    • Place of Presentation
      淡路
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] インスリン感受性調節におけるインターロイキン33の役割について2011

    • Author(s)
      渡部拓,竹内倫徳,窪田直人,坂上慎二,後藤知紗,窪田哲也,西村正治,三品昌美,門脇孝
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 中枢のIRS-2の糖代謝調節における役割の解明-脳特異的IRS-2欠損マウスを用いて-2011

    • Author(s)
      井上真理子,窪田直人,窪田哲也,岩村智勝,佐藤寛之,林高則,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第61回日本体質医学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-10-08
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] プロスタサイクリン誘導体、ベラプロストナトリウムと低用量ピオグリタゾンの併用による糖尿病改善作用の検討2011

    • Author(s)
      熊谷洋紀、高橋雄大、窪田直人、窪田哲也、井上真理子、河合智子、門脇孝
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 視床下部腹内側核(VMH)破壊肥満モデルではアディポネクチン(ADN)産生が充進する2011

    • Author(s)
      鈴木洋子,石塚典子,清水弘行,大坂寿雅,窪田直人,窪田哲也,門脇孝,井上修二
    • Organizer
      第32回日本肥満学会
    • Place of Presentation
      淡路
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Impaired insulin signaling in the endothelial cells reduces insulin-induced glucose uptake by the skeletal muscle2011

    • Author(s)
      Naoto Kubota, Tetsuya Kubota, Hiroki Kumagai, Mariko Inoue, Toshimasa Yamauchi, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      Scientific Sessions 71th American Diabetes Association
    • Place of Presentation
      San Diego
    • Year and Date
      2011-06-26
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 肝臓の糖・脂質代謝におけるIRS-l、IRS-2の役割2010

    • Author(s)
      窪田直人,窪田哲也,熊谷裕紀,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] アディポネクチンの摂食・エネルギー代謝調節メカニズム2010

    • Author(s)
      窪田直人, 窪田哲也, 山内敏正, 植木浩二郎, 箕越靖彦, 門脇孝
    • Organizer
      第31回日本肥満学会
    • Place of Presentation
      群馬
    • Year and Date
      2010-10-11
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] DPP-4阻害薬の2型糖尿病モデル動物に対する長期投与効果の検討2010

    • Author(s)
      中屋恵三, 窪田直人, 高本偉碩, 窪田哲也, 勝山修行, 橋本信嗣, 後藤守兄, 城森孝仁, 植木浩二郎, 門脇孝
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Endothelial insulin-induced eNOS activation regulates capillary ecruitment and glucos uptake in skeletal muscle2010

    • Author(s)
      Naoto Kubota, Tetsuya Kubota, Hiroki Kumagai, Toshimasa Yamauchi, Kohjiro Ueki and Takashi Kadowaki
    • Organizer
      8th International Diabetes Federation Western Pacific Region Congress
    • Place of Presentation
      Busan, Korea
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Endothelial insulin signaling regulates glucose uptake by skeletal muscle2010

    • Author(s)
      Tetsuya Kubota, 1 Naoto Kubota, 1 Hiroki Kumagai1 Mariko Inoue, 1 Iseki Takamoto, 1 Toshimasa Yamauchi, 1 Kohjiro Ueki, 1 and Takashi Kadowaki
    • Organizer
      The 14th international congress of endocrinology
    • Place of Presentation
      Kyoto
    • Year and Date
      2010-03-30
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 肥満・インスリン分泌不全を呈する2型糖尿病モデル動物に対するDPP-4阻害薬の長期投与効果2010

    • Author(s)
      中屋恵三, 窪田直人, 高本偉碩, 窪田哲也, 勝山修行, 橋本信嗣, 後藤守兄, 城森孝仁, 植木浩二郎, 門脇孝
    • Organizer
      第31回日本肥満学会
    • Place of Presentation
      群馬
    • Year and Date
      2010-10-01
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 中枢のIRS-2の糖代謝調節における役割の解明脳特異的IRS-2欠損マウスを用いて2010

    • Author(s)
      井上真理子,窪田直人,窪田哲也,熊谷洋紀,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第83回日本内分泌学会術総会
    • Place of Presentation
      京都
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 肥満・インスリン分泌不全を呈する2型糖尿病モデル動物に対するDPP-4阻害薬の長期投与効果2010

    • Author(s)
      中屋恵三, 窪田直人, 高本偉碩, 窪田哲也, 勝山修行, 橋本信嗣, 後藤守兄, 城森孝仁, 植木浩二郎, 門脇孝
    • Organizer
      第3回日本肥満症治療学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-10
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 肝臓の糖・脂質代謝におけるIRS-1、 IRS-2の役割2010

    • Author(s)
      窪田直人, 窪田哲也, 熊谷裕紀, 山内敏正, 植木浩二郎, 門脇孝
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 骨格筋のインスリン感受性調節における血管内皮細胞のインスリンシグナルの役割の解明2010

    • Author(s)
      窪田哲也,窪田直人,熊谷洋紀,井上真理子,河合智子,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 骨格筋のインスリン感受性調節における血管内皮細胞のインスリンシグナルの役割の解明2010

    • Author(s)
      窪田哲也,窪田直人,熊谷洋紀,井上真理子,河合智子,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第31回日本肥満学会
    • Place of Presentation
      群馬
    • Year and Date
      2010-10-01
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 糖と脂質代謝における肝IRS1とIRS2の生理学的・病態生理学的役割2010

    • Author(s)
      窪田直人, 窪田哲也, 熊谷裕紀, 井上真理子, 河合智子, 山内敏正, 植木浩二郎, 門脇孝
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2010-05-28
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Endothelial insulin signaling regulates capillary recruitment and glucose uptake in skeletal muscle2010

    • Author(s)
      Naoto Kubota, Tetsuya Kubota, Hiroki Kumagai, Mariko Inoue, Tomoko Kawai, Toshimasa Yamauchi, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      Scientific Sessions 70^<th> American Diabetes Association
    • Place of Presentation
      Orlando
    • Year and Date
      2010-06-26
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Endothelial insulin signaling regulates capillary recruitment and glucose uptae in skeleal muse Scientific Sessions2010

    • Author(s)
      Naoto Kubota, Tetsuya Kubota, Hiroki Kumagai, Mariko Inoue, Tomoko Kawai, Toshimasa Yamauchi, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      70th American Diabetes Association
    • Place of Presentation
      Orlando
    • Year and Date
      2010-06-26
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 肝臓の糖・脂質代謝におけるIRS-l、IRS-2の役割2010

    • Author(s)
      窪田直人,窪田哲也,渡部拓,西村正治,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第31回日本肥満学会
    • Place of Presentation
      群馬
    • Year and Date
      2010-10-01
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Endothelial insulin signaling regulates capillary recruitment and glucose uptake in skeletal muscle2010

    • Author(s)
      Tetsuya Kubota, Naoto Kubota, Hiroki Kumagai, Mariko Inoue, Tomoko Kawai, Toshimasa Yamauchi, Kohjiro Ueki 1and Takashi Kadowaki
    • Organizer
      The 2nd Scientific Meeting of the Asian Association for the Study of Diabetes
    • Place of Presentation
      Okayama
    • Year and Date
      2010-05-29
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 膵β細胞のTcf712は膵β細胞量維持に重要な役割を果たしている2010

    • Author(s)
      高本偉碩, 窪田直人, 中屋恵三, 熊谷勝義, 勝山修行, 窪田哲也, 植木浩二郎, 門脇孝
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 血管内皮細胞のインスリンシグナルの糖代謝調節における役割の解明2010

    • Author(s)
      窪田哲也、窪田直人、熊谷洋紀、井上真理子、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第83回日本内分泌学会学術総会
    • Place of Presentation
      京都
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Impaired insulin signaling in the endothelial cells reduces insulin-induced glucose uptake by the skeletal muscle2010

    • Author(s)
      窪田直人、窪田哲也、門脇孝
    • Organizer
      第18回日本血管生物医学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-22
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] チアゾリジン誘導体の抗動脈硬化作用におけるアディポネクチンの役割の解明2010

    • Author(s)
      河合智子,窪田直人,窪田哲也,熊谷洋紀,井上真理子,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Rimonabant Ameliorates Insulin Resistance via both Adiponectin-dependent and Adiponectin-independent Pathways2010

    • Author(s)
      Naoto Kubota, Taku Watanabe, Tetsuya Kubota, Iseki Takamoto, Kohjiro Ueki, and Takashi Kadowaki
    • Organizer
      FASEB Summer Research Conference
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 肝臓の糖・脂質代謝におけるIRS-1、 IRS-2の役割2010

    • Author(s)
      窪田直人, 窪田哲也, 渡部拓, 西村正治, 山内敏正, 植木浩二郎, 門脇孝
    • Organizer
      第31回日本肥満学会
    • Place of Presentation
      群馬
    • Year and Date
      2010-10-01
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 血管内皮細胞インスリンシグナルの糖代謝調節における役割の解明2010

    • Author(s)
      窪田直人,窪田哲也,門脇孝
    • Organizer
      第60回日本体質医学会総会
    • Place of Presentation
      熊本
    • Year and Date
      2010-10-16
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 中枢のIRS-2の糖代謝調節における役割の解明 脳特異的IRS-2欠損マウスを用いて2010

    • Author(s)
      井上真理子, 窪田直人, 窪田哲也, 熊谷洋紀, 河合智子, 山内敏正, 植木浩二郎, 門脇孝
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 中枢のIRS-2の糖代謝調節における役割の解明-脳特異的IRS-2欠損マウスを用いて-2010

    • Author(s)
      井上真理子、窪田直人、窪田哲也、熊谷洋紀、山口真一、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第83回日本内分泌学会学術総会
    • Place of Presentation
      京都
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 肝臓の糖・脂質代謝におけるIRS-1、IRS-2の機能的な役割分担2010

    • Author(s)
      窪田直人,窪田哲也,渡部拓,西村正治,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第83回日本内分泌学会学術総会
    • Place of Presentation
      京都
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 膵β細胞にdominant negative型Tcf7l2を過剰発現させたマウスは耐糖能異常を呈する2009

    • Author(s)
      高本偉碩、窪田直人、中屋恵三、熊谷勝義、勝山修行、渡部拓、窪田哲也、植木浩二郎、宮崎純一、門脇孝
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-22
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] インスリンシグナルの破綻と糖尿病 肝臓の糖・脂質代謝におけるIRS-1、IRS-2の役割2009

    • Author(s)
      窪田直人、窪田哲也、伊藤晋介、山内敏正、寺内康夫、戸辺一之、植木浩二郎、門脇孝
    • Organizer
      第82回日本内分泌学会学術総会
    • Place of Presentation
      前橋
    • Year and Date
      2009-04-23
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] The physiological and pathophysiological roles of Insulin Receptor substrate 1 and 2 in the regulation of glucose and lipid metabolism in the liver2009

    • Author(s)
      Naoto Kubota、Kubota T、Toshimasa Yamauchi、Kohjiro Ueki、Kadowaki T
    • Organizer
      The 15th Korea-Japan Symposium on Diabetes Mellitus
    • Place of Presentation
      Jeju Island
    • Year and Date
      2009-11-19
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 中枢のIRS-2の糖代謝調節における役割の解明-脳特異的IRS-2欠損マウスを用いて2009

    • Author(s)
      井上真理子、窪田直人、窪田哲也、山口真一、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第46回日本臨床分子医学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-04-12
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 血管内皮細胞インスリンシグナルの糖代謝調節における役割の解明2009

    • Author(s)
      窪田哲也、窪田直人、山口真一、井上真理子、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-22
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] IRS-2欠損膵β細胞株の樹立2009

    • Author(s)
      中屋恵三、高本偉碩、窪田直人、熊谷勝義、勝山修行、渡部拓、窪田哲也、植木浩二郎、宮崎純一、門脇孝
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-22
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 骨格筋のインスリン感受性調節における血管内皮細胞のインスリンシグナルの役割の解明2009

    • Author(s)
      窪田哲也
    • Organizer
      第14回アディポサイエンス研究会
    • Place of Presentation
      大阪
    • Year and Date
      2009-08-22
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 血管内皮特異的Akt/PKB欠損マウスの解析2009

    • Author(s)
      鈴木美穂、植木浩二郎、金子和真、窪田哲也、窪田直人、Morris Birnbaum、門脇孝
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-22
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 抗肥満薬リモナバンのインスリン抵抗性改善機構について2009

    • Author(s)
      渡部拓、窪田直人、大杉満、窪田哲也、高本偉碩、窪田哲也、山内敏正、寺内康夫、戸辺一之、植木浩二郎、門脇孝
    • Organizer
      第30回日本肥満学会
    • Place of Presentation
      浜松
    • Year and Date
      2009-10-09
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 肝臓の糖・脂質代謝におけるIRS-1, IRS-2の機能的な役割分担2009

    • Author(s)
      窪田直人,窪田哲也,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第30回日本肥満学会
    • Place of Presentation
      浜松
    • Year and Date
      2009-10-09
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 食事中の脂肪酸組成が肥満やインスリン感受性・耐糖能に与える影響について2009

    • Author(s)
      内山弓子、門脇弘子、加藤美智子、井上真理子、窪田哲也、窪田直人、門脇孝
    • Organizer
      第30回日本肥満学会
    • Place of Presentation
      浜松
    • Year and Date
      2009-10-09
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 肝臓の糖・脂質代謝におけるIRS-1,IRS-2の機能的な役割分担2009

    • Author(s)
      窪田直人、窪田哲也、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第30回日本肥満学会
    • Place of Presentation
      浜松
    • Year and Date
      2009-10-09
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 血管内皮細胞のインスリンシグナルの糖代謝調節における役割の解明2009

    • Author(s)
      窪田哲也、窪田直人、熊谷洋紀、井上真理子、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第59回日本体質医学会総会
    • Place of Presentation
      東京
    • Year and Date
      2009-07-26
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] The physiological and pathophysiological roles of Insulin Receptor substrate 1 and 2 in the regulation of glucose and lipid metabolism in the liver2009

    • Author(s)
      Naoto Kubota、Kubota T、Toshimasa Yamauchi、Kohjiro Ueki, Kadowaki T, The 15th Congress of the ASEAN Federation of Endocrine Societies
    • Organizer
      The 15th Congress of the ASEAN Federation of Endocrine Societies
    • Place of Presentation
      Bangkok
    • Year and Date
      2009-11-28
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] The role of adiponectin in the CNS in the regulation of energy homoeostasis2009

    • Author(s)
      Naoto Kubota, Tetsuya Kubota, Kohjiro Ueki, Toshimasa Yamauchi, Minokoshi Yasuhiko, Takashi Kadowaki
    • Organizer
      Satellite Symposium of the 9th International Symposium on VIP, PACAP and Related Peptides
    • Place of Presentation
      Yakushima
    • Year and Date
      2009-10-02
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] The physiological and pathophysiological roles of Insulin Receptor substrate 1and 2 in the regulation of glucose and lipid metabolism in the liver2009

    • Author(s)
      Naoto Kubota, Tetsuya Kubota, Toshimasa Yamauchi, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      The 15th Korea-Japan Symposium on Diabetes Mellitus
    • Place of Presentation
      Jeju Island
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Pioglitazone Ameliorates Cuff Induced Neointimal Formation by both Adiponectin Dependent and Independent Pathways.2009

    • Author(s)
      Tetsuya Kubota、Naoto Kubota、Iseki Takamoto, Masao Moroi, Kaoru Sugi, Toshimasa Yamauchi, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      第41回日本動脈硬化学会年次学術集会
    • Place of Presentation
      山口
    • Year and Date
      2009-07-18
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 骨格筋のインスリン感受性調節における血管内皮細胞のインスリンシグナルの役割の解明2009

    • Author(s)
      窪田哲也、窪田直人、熊谷洋紀、井上真理子、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第13回日本心血管内分泌学会
    • Place of Presentation
      大宮
    • Year and Date
      2009-10-23
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] The role of adiponectin in the CNS in the regulation of energy homoeostasisi2009

    • Author(s)
      Naoto Kubota, Tetsuya Kubota, Kohjiro Ueki, Toshimasa Yamauchi, Minokoshi Yasuhiko, Takashi Kadowaki
    • Organizer
      Satellite Symposium of the 9th International Symposium on VIP, PACAP and Related Peptides
    • Place of Presentation
      Yakushima
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Pioglitazone Ameliorates Cuff Induced Neointimal Formation by both Adiponectin Dependent and Independent Pathways2009

    • Author(s)
      Tetsuya Kubota, Naoto Kubota, Iseki Takamoto, Masao Moroi, Kaoru Sugi, Toshimasa Yamauchi, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      第41回日本動脈硬化学会年次学術集会
    • Place of Presentation
      山口
    • Year and Date
      2009-07-18
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 抗肥満薬リモナバンのインスリン抵抗性改善機構にはアディポネクチンに依存的なパスウェイと非依存的なパスウェイがある2009

    • Author(s)
      渡部拓、窪田直人、窪田哲也、大杉満、高本偉碩、山内敏正、寺内康夫、戸辺一之、植木浩二郎、門脇孝
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-22
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] The physiological and pathophysiological role ofInsulin Receptor substrate 1 and 2 in the regulation of glucose and lipid metabolism in the liver2009

    • Author(s)
      Naoto Kubota, Tetsuya Kubota, Toshimasa Yamauchi, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      The 15th Congress of the ASEAN Federation of Endocrine Societies
    • Place of Presentation
      Bangkok
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 膵β細胞にdominant negative型Tcf712を過剰発現させたマウスは耐糖能異常を呈する2009

    • Author(s)
      高本偉碩、窪田直人、中屋恵三、熊谷勝義、勝山修行、渡部拓、窪田哲也、植木浩二郎、宮崎純一、門脇孝
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-22
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 糖尿病体質とは 糖尿病の分子生物学の最前線 肝臓の糖・脂質代謝におけるIRS-1、IRS-2の機能的な役割分担2009

    • Author(s)
      窪田直人、窪田哲也、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第59回日本体質医学会
    • Place of Presentation
      東京
    • Year and Date
      2009-07-25
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] アディポネクチンの摂食・エネルギー調節における役割2009

    • Author(s)
      窪田直人、窪田哲也、山内敏正、植木浩二郎、箕越靖彦、門脇孝
    • Organizer
      第62回日本自律神経学会
    • Place of Presentation
      和歌山
    • Year and Date
      2009-11-06
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 中枢のIRS-2の糖代謝調節における役割の解明-脳特異的IRS-2欠損マウスを用いて2009

    • Author(s)
      井上真理子、窪田直人、窪田哲也、山口真一、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-22
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] サルコイドーシス患者の心臓病変評価におけるFDG-PETとBMIPP-SPECTの有用性

    • Author(s)
      中川 尭、廣江道昭、諸岡 都、南本亮吾、伊藤公輝、窪田和雄、山田嘉仁、山口哲生、長田まこと、脇屋桃子、上村宗弘、池田長生、田守唯一、山本正也、伊藤信吾、岡崎 修、原 久男、諸井雅男
    • Organizer
      第22回日本心臓核医学会総会・学術大会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23590907
  • [Presentation] チアゾリジン誘導体はアディポネクチン依存性・非依存性に動脈硬化を抑制する

    • Author(s)
      窪田哲也、窪田直人、井上真理子、林高則、高本偉碩、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第110回日本内科学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25461371
  • [Presentation] チアゾリジン誘導体はアディポネクチン依存性・非依存性に動脈硬化を抑制する

    • Author(s)
      窪田哲也、窪田直人、佐藤寛之、井上真理子、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第86回日本内分泌学会学術総会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-25461371
  • [Presentation] チアゾリジン誘導体はアディポネクチン依存性・非依存性にカフ誘導性の内膜肥厚を抑制する

    • Author(s)
      窪田哲也、窪田直人、佐藤寛之、井上真理子、林高則、相原允一、高本偉碩、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第34回日本肥満学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25461371
  • [Presentation] チアゾリジン誘導体はアディポネクチン依存性・非依存性にカフ誘導性の内膜肥厚を抑制する

    • Author(s)
      窪田哲也、窪田直人、佐藤寛之、井上真理子、林高則、相原允一、高本偉碩、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第56回日本糖尿病学会年次学術集会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-25461371
  • 1.  KUBOTA Naoto (50396719)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 111 results
  • 2.  KADOWAKI Takashi (30185889)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 85 results
  • 3.  MOROI Masao (30256721)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 4.  今中 恭子 (00242967)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 5.  滝 淳一 (10251927)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 6.  廣江 道昭 (80101872)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 7.  INOUE MARIKO (80511477)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 8.  岩部 美紀 (70392529)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  相原 允一 (60779362)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  KAGEYAMA Haruaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  SUZUKI Ryo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  橋本 唯史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  三木 隆司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  長野 学
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  桜井 賛孝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 16.  塩田 清二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  平子 哲史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  植木 浩二郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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